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This record is derived from a genomic sequence (NW_003614777.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509889" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQP1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQP1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100752545", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQP1", "locus": {} } ], "crossref": [ { "id": "A0A9J7FQP1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FQP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10288", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10288", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752545", "url": "https://www.ncbi.nlm.nih.gov/gene/100752545", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752545", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752545", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FQP1", "url": "https://www.orthodb.org/?gene=A0A9J7FQP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11417", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11417", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11417:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11417:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509889", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509889", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FQP1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FQP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLTLTLPRSAGMCMLLLVSTLLLWEHVASKPSGLMSIEALYNRVVEYSHITYVLAADIYREFDLNFFKRSWFTDRTLSLCHTASIYTPETRQEVHDTKTEDLLKAIVNITHSWEEPLKHLLSAVPTLQGASDNMLKSANAVKERNHILLEGIEAILNRTQVEIEDDAYPDWSGLSDLQSSDEETRLFEFFNLCRCLRRDTHKVDTFLKVLRCRFVYNNECMYYQ", "length": 225, "header": "tr|A0A9J7FQP1-1|A0A9J7FQP1_CRIGR Isoform 1 of Prolactin-3D1-like OS=Cricetulus griseus OX=10029 GN=LOC100752545 PE=3 SV=1 CANONICAL=A0A9J7FQP1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FQP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQP1/entry#A0A9J7FQP1-1", "sequence": { "sequence": "MQLTLTLPRSAGMCMLLLVSTLLLWEHVASKPSGLMSIEALYNRVVEYSHITYVLAADIYREFDLNFFKRSWFTDRTLSLCHTASIYTPETRQEVHDTKTEDLLKAIVNITHSWEEPLKHLLSAVPTLQGASDNMLKSANAVKERNHILLEGIEAILNRTQVEIEDDAYPDWSGLSDLQSSDEETRLFEFFNLCRCLRRDTHKVDTFLKVLRCRFVYNNECMYYQ", "length": 225, "header": "tr|A0A9J7FQP1-1|A0A9J7FQP1_CRIGR Isoform 1 of Prolactin-3D1-like OS=Cricetulus griseus OX=10029 GN=LOC100752545 PE=3 SV=1 CANONICAL=A0A9J7FQP1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQP1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQP1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752545", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752545", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "prolactin receptor binding", "id": "GO:0005148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005148", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQP1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQP1" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265895" } ] }, { "annotation": "Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. 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"MQELRGILLCLLLAAAVPTTPAPAPTATWTPVEPGPALSYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAARTSSEVNLSSLPANYHNETNTDARVGNNTVHMHQEIHKTTNNKTGQMVFSETVITSVGDEEGKRSHECIIDEDCGPTRYCQFSSFTYTCQPCRDQQMLCTRDSECCGDQLCVWGHCTKKASKGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTFLPVEGELCHDPASQLLELITWELEPEGALDRCPCASGLLCQPHSHSLAYVCKQAFVGSHDQNEESLLPRETPDEYEDGGFIGEVRQELEDLERSLAQDMAFGDSIPEESLGGGEI", "length": 348, "header": "tr|A0A9J7FQR4-1|A0A9J7FQR4_CRIGR Isoform 1 of Dickkopf-related protein 3 OS=Cricetulus griseus OX=10029 GN=Dkk3 PE=3 SV=1 CANONICAL=A0A9J7FQR4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FQR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQR4/entry#A0A9J7FQR4-1", "sequence": { "sequence": "MQELRGILLCLLLAAAVPTTPAPAPTATWTPVEPGPALSYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAARTSSEVNLSSLPANYHNETNTDARVGNNTVHMHQEIHKTTNNKTGQMVFSETVITSVGDEEGKRSHECIIDEDCGPTRYCQFSSFTYTCQPCRDQQMLCTRDSECCGDQLCVWGHCTKKASKGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTFLPVEGELCHDPASQLLELITWELEPEGALDRCPCASGLLCQPHSHSLAYVCKQAFVGSHDQNEESLLPRETPDEYEDGGFIGEVRQELEDLERSLAQDMAFGDSIPEESLGGGEI", "length": 348, "header": "tr|A0A9J7FQR4-1|A0A9J7FQR4_CRIGR Isoform 1 of Dickkopf-related protein 3 OS=Cricetulus griseus OX=10029 GN=Dkk3 PE=3 SV=1 CANONICAL=A0A9J7FQR4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ43-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQR4/entry#A0A9J7JJ43-1", "sequence": { "sequence": "MQELRGILLCLLLAAAVPTTPAPAPTATWTPVEPGPALSYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAARTSSEVNLSSLPANYHNETNTDARVGNNTVHMHQEIHKECIIDEDCGPTRYCQFSSFTYTCQPCRDQQMLCTRDSECCGDQLCVWGHCTKKASKGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTFLPVEGELCHDPASQLLELITWELEPEGALDRCPCASGLLCQPHSHSLAYVCKQAFVGSHDQNEESLLPRETPDEYEDGGFIGEVRQELEDLERSLAQDMAFGDSIPEESLGGGEI", "length": 320, "header": "tr|A0A9J7JJ43-1|A0A9J7JJ43_CRIGR Computationally mapped isoform of Dickkopf-related protein 3 OS=Cricetulus griseus OX=10029 GN=Dkk3 PE=3 SV=1 CANONICAL=A0A9J7FQR4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQR4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQR4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQR4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQR4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767109", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQR4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQR4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQR4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQR4" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQR4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQR4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "receptor antagonist activity", "id": "GO:0048019", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048019", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQR4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQR4" } ], "pmid": "" }, { "name": "co-receptor binding", "id": "GO:0039706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039706", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQR4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQR4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FQR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQR4" }, { "id": "PF04706", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04706" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dickkopf N-terminal cysteine-rich", "eco_id": "ECO_0000259", "start_pos": 146, "end_pos": 196, "start_aa": "Glu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 121, "end_pos": 123 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 86, "end_pos": 88 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] 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"https://www.ncbi.nlm.nih.gov/protein/XP_027263213" }, "gene_names": [ { "name": "LOC100751491", "type": "recommended", "evidence": [ { "id": "A0A9J7FQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV0" } ] }, { "name": "LOC100751491", "type": "synonym", "evidence": [ { "id": "XP_027263213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263213" } ] } ], "protein_names": [ { "name": "unspecific monooxygenase", "type": "recommended", "evidence": [ { "id": "A0A9J7FQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV0/entry#names_and_taxonomy" } ] }, { "name": "1.14.14.1", "type": "synonym", "evidence": [ { "id": "A0A9J7FQV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV0/entry#names_and_taxonomy" } ] }, { "name": "cytochrome P450 2C26 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027263213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263213" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263213" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQV0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100751491", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV0", "locus": {} } ], "crossref": [ { "id": "A0A9J7FQV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FQV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20665", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20665", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751491", "url": "https://www.ncbi.nlm.nih.gov/gene/100751491", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751491", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751491", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FQV0", "url": "https://www.orthodb.org/?gene=A0A9J7FQV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027263213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263213", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FQV0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FQV0-1", "url": 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OS=Cricetulus griseus OX=10029 GN=LOC100751491 PE=3 SV=1 CANONICAL=A0A9J7FQV0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FQV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV0/entry#A0A9J7FQV0-1", "sequence": { "sequence": "MDPAVVLVFILSCLVLLSLWRQRSERGKLPPGPTPLPLIGNFLQIDVKDISRSLTNLSKVYGPMFTLYMGMKPTVVLHGYEAVKEALIDHGEEFAGRGSFPMAERLNKGFGIIFSSGSRWKETRRFTLMTLRNLGMGKRSIEDCVQEEAQCLVEELRKTNGSPCDPTFILSCAPCNVICSIIFQKRFDYKDHHFLTLMEKVNENSRILSSPWLQVCNNFSSLIDYCPGSHHTITKNFNYIRSYLLEKIKEHQESLDDANPRDFIDCYLIKMKQANHNQQSEFSLENLAITLSDLFAAGTETTSTTLRYALLLLLKHPHVTAKVQEEIDQVVGRDRSPSMQDRSRMPYTDAMVHEVQRFIDLVPTNLPHAVTCDIKFRDFFIPKGTTIITSLSSVLHDSKEFPNPEVFDPGHFLDKNGNFKKSDYFMPFSTGKRICAGEGLARMELFLFLTTILQNFKLKSLVHTKDIDTNPVVNGLTSLPPPFQLCFIPV", "length": 490, "header": "tr|A0A9J7FQV0-1|A0A9J7FQV0_CRIGR Isoform 1 of unspecific monooxygenase OS=Cricetulus griseus OX=10029 GN=LOC100751491 PE=3 SV=1 CANONICAL=A0A9J7FQV0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GV00-1", "url": 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"id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FQV7-1", "uniprot_ac": "A0A9J7FQV7", "uniprot_id": "A0A9J7FQV7_CRIGR", "mass": { "chemical_mass": 65277.0, "monoisotopic_mass": 65277.0 }, "refseq": { "ac": "XP_007653431", "name": "acyl-coenzyme A synthetase ACSM4, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653431" }, "gene_names": [ { "name": "LOC100755056", "type": "recommended", "evidence": [ { "id": "A0A9J7FQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV7" } ] }, { "name": "LOC100755056", "type": "synonym", "evidence": [ { "id": "XP_007653431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653431" } ] } ], "protein_names": [ { "name": "medium-chain acyl-CoA ligase", "type": "recommended", "evidence": [ { "id": "A0A9J7FQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV7/entry#names_and_taxonomy" } ] }, { "name": "6.2.1.2", "type": "synonym", "evidence": [ { "id": "A0A9J7FQV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV7/entry#names_and_taxonomy" } ] }, { "name": "acyl-coenzyme A synthetase ACSM4, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_007653431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653431" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617609.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007653431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653431" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQV7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100755056", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV7", "locus": {} } ], "crossref": [ { "id": "A0A9J7FQV7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FQV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05928", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05928", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755056", "url": "https://www.ncbi.nlm.nih.gov/gene/100755056", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755056", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755056", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QLWTPLT", "url": "https://omabrowser.org/oma/group/QLWTPLT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FQV7", "url": "https://www.orthodb.org/?gene=A0A9J7FQV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43605", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43605", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43605:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43605:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007653431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653431", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "48340", "url": "https://www.rhea-db.org/rhea/48340", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FQV7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FQV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKILLHYQRFRFIWLAKPAGRHFHKHPQLQTPLTLADFEAINRCEKPLPKNFNFAADVLDQWSQKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACIRTGLVFMPGTTQLTRKDILYRLQASKAKCIVASEEVAPAVDSIVSECPNLKTKLLVSPDRWDGWLNFQELLPLASEEHSCVETGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTPSDIMWNMSDTGWIKAAIGSVFSTWLQGACVFVHRMAQFDTDTFLDTLTTYPITTLCSAPTVYRMLVQKDLKRYQFKRLRHCLTGGEPLNPEVLEQWKVQTGLELYEGYGQTEVGIICANCKGQEIKPGSMGKGVVPYDVQIIDESGNVLPPGKEGEIALRLESTRPFCFFSEYVDNPEKTAATIRRNFYVTGDRGVMDNDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPFKSSNREKLIAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWGRA", "length": 580, "header": "tr|A0A9J7FQV7-1|A0A9J7FQV7_CRIGR Isoform 1 of medium-chain acyl-CoA ligase OS=Cricetulus griseus OX=10029 GN=LOC100755056 PE=3 SV=1 CANONICAL=A0A9J7FQV7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FQV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV7/entry#A0A9J7FQV7-1", "sequence": { "sequence": "MKILLHYQRFRFIWLAKPAGRHFHKHPQLQTPLTLADFEAINRCEKPLPKNFNFAADVLDQWSQKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACIRTGLVFMPGTTQLTRKDILYRLQASKAKCIVASEEVAPAVDSIVSECPNLKTKLLVSPDRWDGWLNFQELLPLASEEHSCVETGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTPSDIMWNMSDTGWIKAAIGSVFSTWLQGACVFVHRMAQFDTDTFLDTLTTYPITTLCSAPTVYRMLVQKDLKRYQFKRLRHCLTGGEPLNPEVLEQWKVQTGLELYEGYGQTEVGIICANCKGQEIKPGSMGKGVVPYDVQIIDESGNVLPPGKEGEIALRLESTRPFCFFSEYVDNPEKTAATIRRNFYVTGDRGVMDNDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPFKSSNREKLIAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWGRA", "length": 580, "header": "tr|A0A9J7FQV7-1|A0A9J7FQV7_CRIGR Isoform 1 of medium-chain acyl-CoA ligase OS=Cricetulus griseus OX=10029 GN=LOC100755056 PE=3 SV=1 CANONICAL=A0A9J7FQV7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQV7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQV7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQV7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755056", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755056", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3N2S1-1", "protein_name": "medium-chain acyl-CoA ligase", "gene_name": "ACSM4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKIFFRYQTFRFIWLTKPIGRRFHKSHQLGAPLTLADFEAINRCERSLPKNFNFAGDVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFGELGSLSRKAANVLTKPCGLERGDRVAVILPRIPEWWLINVACMRTGLVFMPGTTQLTAKDILYRLHASKAKCIVASEEVIPAVESIVSECPDLKTKLLVSPHSQDGWLSFPELFQTASAEHSCVETGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYTLCGRYWLDLKSTDIIWNMSDTGWIKAAIGSVFSSWLQGACVFVHRMAQFDTDTFLDTLTTYPITTLCSAPTVYRMLVQKDLKRYKFKKLRHCLTGGEPLNPEVLEQWKVQTGLELYEGYGQTEVGIICANQKGQEIKPGSMGKGVLPYDVQIIDENGNILPPGKEGEIALRLTSTRPFCFFSEYVDNPEKTAATIRGNFYVTGDRGVMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPVRGEVVKAFVVLSAPFKSSNPEKLTLELQDHVKKSTAPYKYPRKVEFVKELPKTITGKIKRNVLRDHEWGRT", "length": 580 }, "evidence": [ { "id": "A0A9J7FQV7", "url": "https://omabrowser.org/oma/group/A0A9J7FQV7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LSY0-1", "protein_name": "medium-chain acyl-CoA ligase", "gene_name": "ACSM4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKIFSCYQTFRFIRLTKPPGRRFHKDYQLQVPLTLDDLEAIMLCERPLPKSFNFAADVLDQWSQKEKTGERPANPALWWVNSQGNEVKWSFRELGSLSRKAANVLTKSCGLERGDRVAMILPRIPEWWLLNVACMRTGLVFMPGTTQLTAKDLLYRLRASKAKCIVASDEVVPAVESAASECPDLKTKLLVSPHSRNGWLSFQELFQNASTEHSCVETGSQESMAIFFTSGTSGSPKMAQHSQSSLGIGSTHCGRHWFDLKSSDTMWNISDTGWIKASLGSLFSPWLMGSCVFVHRMAQFDTDTVLDVLATYPITTLCGPPTVYRMLVQKDLRRYKFKSLKHCLTGGEPLNPEVLEQWRAQTGLNLYEGYGQTEVGLICASYKGQEIKPGSMGIRAPPHDVQIIDENGDVLPPGKEGEISIRLTPTRHFSLFSKYVDNPEKTAATIRGGFYVTGDRGVMDSDGYFRFVGRADDVIISAGYRIGPFEVESALIEHPAVAESAVVSSPDPIRGEVVKAFVVLSAPFKSSNPEQLTLELQDHVKKSTAPYKYPRKVEFVQELPKTVTGKIKRNILRDREWGRA", "length": 580 }, "evidence": [ { "id": "A0A9J7FQV7", "url": "https://omabrowser.org/oma/group/A0A9J7FQV7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C7M7-1", "protein_name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "gene_name": "ACSM4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIFFRYQTFRFIWLTKPPGRRLHKDHQLWTPLTLADFEAINRCNRPLPKNFNFAADVLDQWSQKEKTGERPANPALWWVNGKGDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLVSPQSWNGWLSFQELFQFASEEHSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYWLDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTLCSPPTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTGLELYEGYGQTEVGMICANQKGQEIKPGSMGKGMLPYDVQIIDENGNVLPPGKEGEIALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYVTGDRGVMDSDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKSYNPEKLTLELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWRGR", "length": 580 }, "evidence": [ { "id": "A0A9J7FQV7", "url": "https://omabrowser.org/oma/group/A0A9J7FQV7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q42524-1", "protein_name": "4-coumarate--CoA ligase 1", "gene_name": "4CL1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPQEQAVSQVMEKQSNNNNSDVIFRSKLPDIYIPNHLSLHDYIFQNISEFATKPCLINGPTGHVYTYSDVHVISRQIAANFHKLGVNQNDVVMLLLPNCPEFVLSFLAASFRGATATAANPFFTPAEIAKQAKASNTKLIITEARYVDKIKPLQNDDGVVIVCIDDNESVPIPEGCLRFTELTQSTTEASEVIDSVEISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPMVPPIVLAIAKSSETEKYDLSSIRVVKSGAAPLGKELEDAVNAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSELSEDDVKQFVSKQVVFYKRINKVFFTESIPKAPSGKILRKDLRAKLANGL", "length": 561 }, "evidence": [ { "id": "A0A9J7FQV7", "url": "https://omabrowser.org/oma/group/A0A9J7FQV7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q7TN78-1", "protein_name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "gene_name": "Acsm4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKVLLRCQRLRFIWLAKPAGRHFHRDPQLWAPLTLDDFEAINRCEKPLPKNFNFAADVLDQWSLKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQLTRKDILYRLQASKAKCIVASEEVAPAVDSIASECPNLKTKLLVSPHRWDGWLSFQELLQSASEEHNCVQTGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFSTWLRGACVFVHRMAQFNTDTFLDTLTSYPITTLCSAPTVYRMLVQQDLKRYQFKRLRHCLTGGEPLNPEVLEQWKAQTGLELYEGYGQTEVGIICANRKGEEIKPGSMGKGVVPYDVQIIDEHGNILPSGKEGEIALRLGSDRPFCFFSEYVDNPEKTDATIRRNFYITGDRGVMDDDGYLWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPFKSSNREKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWGRA", "length": 580 }, "evidence": [ { "id": "A0A9J7FQV7", "url": "https://omabrowser.org/oma/group/A0A9J7FQV7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80W40-1", "protein_name": "Acyl-coenzyme A synthetase ACSM4, mitochondrial", "gene_name": "Acsm4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKVLLHCQRLRFIWLAKPAGRHFHRDSQLWAPLTLDDFEAINRCEKPLPKNFNFAADVLDQWSLKEKSGERPANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLINVACMRTGLVFMPGTIQLTRKDILYRLQASKAKCIVASEEVAPAVDSIVSECPSLKTKLLVSPHHWDGWLNFQELLQSASEEHNCVETGSQEPMAIYFTSGTTGSPKMAQHSQGSLGIGYTLCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFSTWLRGACVFVHRMAQFDTDIFLDTLTTYPITTLCSAPTVYRMLVQKDLKRYQFKRLRHCLTGGEPLNPEVLEQWKMQTGLELYEGYGQTEVGIICANRKGEAIKPGSMGKGVVPYDVQIIDENGNILPSGKEGEIALRLKSDRPFCFFSEYVDNPEKTDATIRRNFYVTGDRGVMDDDGYFWFVGRADDVIISSGYRIGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPYKCSNREKLTAELQDHVKNSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQEWGRA", "length": 580 }, "evidence": [ { "id": "A0A9J7FQV7", "url": "https://omabrowser.org/oma/group/A0A9J7FQV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": 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This record is derived from a genomic sequence (NW_003615473.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007651164.1. 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"A0A9J7FQY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQY2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQY2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ceramide biosynthetic process", "id": "GO:0046513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046513", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36547", "name": "", "equation": "sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "36547", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36547" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FQY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQY2" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 83, "end_pos": 127, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FQY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQY2" }, { "id": "PS50922", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50922" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TLC", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 331, "start_aa": "Lys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"A0A9J7FQZ5-1", "uniprot_ac": "A0A9J7FQZ5", "uniprot_id": "A0A9J7FQZ5_CRIGR", "mass": { "chemical_mass": 111271.0, "monoisotopic_mass": 111271.0 }, "refseq": { "ac": "XP_027265966", "name": "centriolar coiled-coil protein of 110 kDa isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265966" }, "gene_names": [ { "name": "Ccp110", "type": "recommended", "evidence": [ { "id": "A0A9J7FQZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5" } ] }, { "name": "Ccp110", "type": "synonym", "evidence": [ { "id": "XP_027265966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265966" } ] } ], "protein_names": [ { "name": "Centriolar coiled-coil protein of 110 kDa isoform X4", "type": "synonym", "evidence": [ { "id": "A0A9J7FQZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5/entry#names_and_taxonomy" } ] }, { "name": "centriolar coiled-coil protein of 110 kDa isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027265966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265966" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265966" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccp110", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5", "locus": {} } ], "crossref": [ { "id": "A0A9J7FQZ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FQZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100775002", "url": "https://www.ncbi.nlm.nih.gov/gene/100775002", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100775002", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775002", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FQZ5", "url": "https://www.orthodb.org/?gene=A0A9J7FQZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13594", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13594", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13594:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13594:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265966", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FQZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JET1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JET1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JET1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JET1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JL48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JL48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JL48-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JL48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLV6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEYEEFCEKALARVQEASISEESFLPAQAQSVSLIRFHGVAVLSPLLTIEKRKEIQQEKQKALDVQTRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETLYCNPEFRDLNAPATVPNNLLGPTEHCTPVKLEKITGLLPLGNKDQHSPNGLSLLRDSKGFGSPKRGASPDSRQTVNGAAPRLSAGSSQETQISDSPLLAKEEQDPSCLADITPDPYIMSLQNLMKKSKEYIEREQSRRSLRSSAKRSGSESHSDKENDAKASDCVKEKAPPTGRHCGSTIPDKPSLNKSNVLLQGASQASNMGTSVLATFSKVDLPVGTDSPAVPDAESAFKVFPTFITENKVIKTLTGPYAKLPSPEPSVSPTMHRRRSRPSSACQILINNPVNACELSPKGKEEAVDRVAPAVAETTNEFEIVPKSPADLTGVCSSKVSASKVMLDTTKDMVVGKPSQVHQALGNQLDNKVTVEHAAMEAPITPDEREIQKVDSTCMAVPKLQELHATSQCVASQAMEDVCGLKSASMLVKNSCNLQMELNKSYDVKSPSPLLMQTQNSRQQMDTSPVPCGNEQFLDNSFEKVKRRLDLDIDTLQKENCPYIVTAGVAEQEHLPERRYPKGSVCMNRNKMLETSPKEGQEVKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQREIEEQEKMLTEKAVTADVSDLNSALELEWRKRSGSALLETVLSQVDLLQASDNSGFTNSALQYSFGSASEAPFYLWGSLASGMTKLSVTRPFGRTQAKWSQVFSPEIQAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMKSPRVALSAATQKSLDRKKFMKVAEMGMPNKKFLLKQNPSETRVLQPNQGQNAPVHRLLCRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGVYAGKIQRKRPNVATI", "length": 1003, "header": "tr|A0A9J7FQZ5-1|A0A9J7FQZ5_CRIGR Isoform 1 of Centriolar coiled-coil protein of 110 kDa isoform X4 OS=Cricetulus griseus OX=10029 GN=Ccp110 PE=4 SV=1 CANONICAL=A0A9J7FQZ5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FQZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5/entry#A0A9J7FQZ5-1", "sequence": { "sequence": "MEEYEEFCEKALARVQEASISEESFLPAQAQSVSLIRFHGVAVLSPLLTIEKRKEIQQEKQKALDVQTRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETLYCNPEFRDLNAPATVPNNLLGPTEHCTPVKLEKITGLLPLGNKDQHSPNGLSLLRDSKGFGSPKRGASPDSRQTVNGAAPRLSAGSSQETQISDSPLLAKEEQDPSCLADITPDPYIMSLQNLMKKSKEYIEREQSRRSLRSSAKRSGSESHSDKENDAKASDCVKEKAPPTGRHCGSTIPDKPSLNKSNVLLQGASQASNMGTSVLATFSKVDLPVGTDSPAVPDAESAFKVFPTFITENKVIKTLTGPYAKLPSPEPSVSPTMHRRRSRPSSACQILINNPVNACELSPKGKEEAVDRVAPAVAETTNEFEIVPKSPADLTGVCSSKVSASKVMLDTTKDMVVGKPSQVHQALGNQLDNKVTVEHAAMEAPITPDEREIQKVDSTCMAVPKLQELHATSQCVASQAMEDVCGLKSASMLVKNSCNLQMELNKSYDVKSPSPLLMQTQNSRQQMDTSPVPCGNEQFLDNSFEKVKRRLDLDIDTLQKENCPYIVTAGVAEQEHLPERRYPKGSVCMNRNKMLETSPKEGQEVKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQREIEEQEKMLTEKAVTADVSDLNSALELEWRKRSGSALLETVLSQVDLLQASDNSGFTNSALQYSFGSASEAPFYLWGSLASGMTKLSVTRPFGRTQAKWSQVFSPEIQAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMKSPRVALSAATQKSLDRKKFMKVAEMGMPNKKFLLKQNPSETRVLQPNQGQNAPVHRLLCRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGVYAGKIQRKRPNVATI", "length": 1003, "header": "tr|A0A9J7FQZ5-1|A0A9J7FQZ5_CRIGR Isoform 1 of Centriolar coiled-coil protein of 110 kDa isoform X4 OS=Cricetulus griseus OX=10029 GN=Ccp110 PE=4 SV=1 CANONICAL=A0A9J7FQZ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JET1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5/entry#A0A9J7JET1-1", "sequence": { "sequence": "MEEYEEFCEKALARVQEASISEESFLPAQAQSVSLIRFHGVAVLSPLLTIEKRKEIQQEKQKALDVQTRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETLYCNPEFRDLNAPATVPNNLLGPTEHCTPVKLEKITGLLPLGNKDQHSPNGLSLLRDSKGFGSPKRGASPDSRQTVNGAAPRLSAGSSQETQISDSPLLAKEEQDPSCLADITPDPYIMSLQNLMKKSKEYIEREQSRRSLRSSAKRSGSESHSDKENDAKASDCVKEKAPPTGRHCGSTIPDKPSLNKSNVLLQGASQASNMGTSVLATFSKVDLPVGTDSPAVPDAESAFKVFPTFITENKVIKTLTGPYAKLPSPEPSVSPTMHRRRSRPSSACQILINNPVNACELSPKGKEEAVDRVAPAVAETTNEFEIVPKSPADLTGVCSSKVSASKVMLDTTKDMVVGKPSQVHQALGNQLDNKVTVEHAAMEAPITPDEREIQKVDSTCMAVPKLQELHATSQCVASQAMEDVCGLKSASMLVKNSCNLQMELNKSYDVKSPSPLLMQTQNSRQQMDTSPVPCGNEQFLDNSFEKVKRRLDLDIDTLQKENCPYIVTAGVAEQEHLPERRYPKGSVCMNRNKMLETSPKGQEVKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQREIEEQEKMLTEKAVTADVSDLNSALELEWRKRSGSALLETVLSQVDLLQASDNSGFTNSALQYSFGSASEAPFYLWGSLASGMTKLSVTRPFGRTQAKWSQVFSPEIQAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIRSFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMKSPRVALSAATQKSLDRKKFMKVAEMGMPNKKFLLKQNPSETRVLQPNQGQNAPVHRLLCRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGVYAGKIQRKRPNVATI", "length": 1002, "header": "tr|A0A9J7JET1-1|A0A9J7JET1_CRIGR Computationally mapped isoform of Centriolar coiled-coil protein of 110 kDa isoform X5 OS=Cricetulus griseus OX=10029 GN=Ccp110 PE=4 SV=1 CANONICAL=A0A9J7FQZ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JL48-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5/entry#A0A9J7JL48-1", "sequence": { "sequence": "MEEYEEFCEKALARVQEASISEESFLPAQAQSVSLIRFHGVAVLSPLLTIEKRKEIQQEKQKALDVQTRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETLYCNPEFRDLNAPATVPNNLLGPTEHCTPVKLEKITGLLPLGNKDQHSPNGLSLLRDSKGFGSPKRGASPDSRQTVNGAAPRLSAGSSQETQISDSPLLAKEEQDPSCLADITPDPYIMSLQNLMKKSKEYIEREQSRRSLRSSAKRSGSESHSDKENDAKASDCVKEKAPPTGRHCGSTIPDKPSLNKSNVLLQGASQASNMGTSVLATFSKVDLPVGTDSPAVPDAESAFKVFPTFITENKVIKTLTGPYAKLPSPEPSVSPTMHRRRSRPSSACQILINNPVNACELSPKGKEEAVDRVAPAVAETTNEFEIVPKSPADLTGVCSSKVSASKVMLDTTKDMVVGKPSQVHQALGNQLDNKVTVEHAAMEAPITPDEREIQKVDSTCMAVPKLQELHATSQCVASQAMEDVCGLKSASMLVKNSCNLQMELNKSYDVKSPSPLLMQTQNSRQQMDTSPVPCGNEQFLDNSFEKVKRRLDLDIDTLQKENCPYIVTAGVAEQEHLPERRYPKGSVCMNRNKMLETSPKEGQEVKSKMLAFEEMRKRLEEQHAQQLSLLIAEQEREQERLQREIEEQEKMLTEKAVTADVSDLNSALELEWRKRSGSALLETVLSQVDLLQASDNSGFTNSALQYSFGSASEAPFYLWGSLASGMTKLSVTRPFGRTQAKWSQVFSPEIQAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKLRAALYGIHDIFFVMDAAERMSILHHDREARKEKLLRQMDKMKSPRVALSAATQKSLDRKKFMKVAEMGMPNKKFLLKQNPSETRVLQPNQGQNAPVHRLLCRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGVYAGKIQRKRPNVATI", "length": 969, "header": "tr|A0A9J7JL48-1|A0A9J7JL48_CRIGR Computationally mapped isoform of Centriolar coiled-coil protein of 110 kDa isoform X7 OS=Cricetulus griseus OX=10029 GN=Ccp110 PE=4 SV=1 CANONICAL=A0A9J7FQZ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5/entry#A0A9J7JLV6-1", "sequence": { "sequence": 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"header": "tr|A0A9J7JLV6-1|A0A9J7JLV6_CRIGR Computationally mapped isoform of Centriolar coiled-coil protein of 110 kDa isoform X6 OS=Cricetulus griseus OX=10029 GN=Ccp110 PE=4 SV=1 CANONICAL=A0A9J7FQZ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:1903723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5" } ], "pmid": "" }, { "name": "ciliary basal body organization", "id": "GO:0032053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032053", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264382" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sipa1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQZ6", "locus": {} } ], "crossref": [ { "id": "cd06745", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06745", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762087", "url": "https://www.ncbi.nlm.nih.gov/gene/100762087", "database": "GeneID", "categories": [ "Genome 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15711:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15711:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027264382", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264382", "database": "RefSeq", "categories": [ 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"length": 1044, "header": "tr|A0A9J7FQZ6-1|A0A9J7FQZ6_CRIGR Isoform 1 of Signal-induced proliferation-associated protein 1 OS=Cricetulus griseus OX=10029 GN=Sipa1 PE=4 SV=1 CANONICAL=A0A9J7FQZ6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 64, "start_aa": "Thr", "end_pos": 64, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr64", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly 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This record is derived from a genomic sequence (NW_003613757.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016829868.1. 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{}, "start_pos": 497, "start_aa": "Thr", "end_pos": 497, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr497", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FR61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FR61" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266794" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRB9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cep162", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9", "locus": {} } ], "crossref": [ { "id": "100759950", "url": "https://www.ncbi.nlm.nih.gov/gene/100759950", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759950", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759950", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FRB9", "url": "https://www.orthodb.org/?gene=A0A9J7FRB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34031", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34031", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34031:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34031:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27821", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27821", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27882", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27882", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27944", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27944", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266794", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266794", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MVK6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MVK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRB9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JN90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JN90-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFHFSKEELDEEFEQFMKELSDDSFESSNKTSKQPKKEMKKKDTVPWWITEDDFDDDLFLELLRTNVSYLKTKKTSQPIMDTEEESAEKAQFLKSSGTSILSVDSLEANELVLSELHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDSDDSTQFRALHSYLANTEPAEDGHESESEHEGLPETYSDDFEDAEDVDAPLITEKEETHPAENSESGRAHVPAQEEEKTGMLANVVLLDSLDSVEDVNLADQSKATPEAKALPEVTGGELTGTGVSYGQSSGDTEALHQAYCHIAHSLGDTGKPRIEASTVANAKSSVKDHLQENEESSKNISTTESDLPTVEELMKPIRIDSYGVSGFDLPPISLKKAADSKEGESVSSLLHKMNTNTVSQDPTHVNQFPYKHDENVTLHKTEGEIMGGGCPAATAMEERLDKMYLEILKKKTTVNPSLLPQDDKTNQTSRTQLSAGEEGPVTGKQVPYKKARSAPPLLKRKPQSGLYMSARSSGYGKPTSSLQLFSALEKKTSKDNTKSKNVRSIPTSNQFRKKEILSGTKLIKPAALNRPSPQSEGSLTTPKQPEDPTADSSVQFQTEPPGNGEKELLMLKRAQEAEEKWRGAQALIEQIKVTFSEKERELENTLETLKRQQEGELFKLNQENYILQTKLSSFEETSRKQRWLQLGETSDPITGEKLKQIQKEIEEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQNLFSELASLKEQVHKNRFLSQAVENAEPTKNQSFTDLLAELRVVQKEKNHLMEDIKRLKQDKQALEVDLEKVKKERDQAKDQIAYATGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDKDAARLREANEEAEKLKLEIEKLKTESGSPTTQQRLRSKERALDAKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSADRNTVEFMERRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQLLAHRLKEAPQNQRNSSARLKALETELGEIKEAHEVTVRKLEAEISDLKHQNAALEHKKNDREDQDLQSLEFQVEQAHAKAKLARLNEELAAKGREIQDLSKTVERLQKERRMMLSRQGPRSREETSAKQVKKEVLHPSRGNANSFSGTLDAKLYHPHTFTDSHVSEVLQENYRLRKELEGLILERNKLKMDSEAAVYQFENSMKRVKDDTAAHIASLKASHQREMEKILCQNALENSSSKVAELNRKIITQEVLIKHFQGQVNELQGKQESLAVSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIKQMEMRHKQREQELQQIIQQTRQVVETEQNKEVEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPVALADEVNTAEF", "length": 1405, "header": "tr|A0A9J7FRB9-1|A0A9J7FRB9_CRIGR Isoform 1 of Centrosomal protein of 162 kDa OS=Cricetulus griseus OX=10029 GN=Cep162 PE=3 SV=1 CANONICAL=A0A9J7FRB9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MVK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9/entry#A0A8C2MVK6-1", "sequence": { "sequence": "MFHFSKEELDEEFEQFMKELSDDSFESSNKTSKQPKKEMKKKDTVPWWITEDDFDDELLRTNVSYLKTKKTSQPIMDTEEESAEKAQFLKSSGTSILSVDSLEANELVLSELHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDSDDSTQFRALHSYLANTEPAEDGHESESEHEGLPETYSDDFEDAEDVDAPLITEKEETHPAENSESGRAHVPAQEEEKTGMLANVVLLDSLDSVEDVNLADQSKATPEAKALPEVTGGELTGTGVSYGQSSGDTEALHQAYCHIAHSLGDTGKPRIEASTVANAKSSVKDHLQENEESSKNISTTESDLPTVEELMKPIRIDSYGVSGFDLPPISLKKAADSKEGESVSSLLHKMNTNTVSQDPTHVNQFPYKHDENVTLHKTEGEIMGGGCPAATAMEERLDKMYLEILKKKTTVNPSLLPQDDKTNQTSRTQLSAGEEGPVTGKQVPYKKARSAPPLLKRKPQSGLYMSARSSGYGKPTSSLQLFSALEKKTSKDNTKSKNVRSIPTSNQFRKKEILSGTKLIKPAALNRPSPQSEGSLTTPKQPEDPTADSSVQFQTEPPGNGEKELLMLKRAQEAEEKWRGAQALIEQIKVTFSEKERELENTLETLKRQQEGELFKLNQENYILQTKLSSFEETSRKQRWLQLGETSDPITGEKLKQIQKEIEEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQNLFSELASLKEQVHKNRFLSQAVENAEPTKNQSFTDLLAELRVVQKEKNHLMEDIKRLKQDKQALEVDLEKVKKERDQAKDQIAYATGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDKDAARLREANEEAEKLKLEIEKLKTESGSPTTQQRLRSKERALDAKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSADRNTVEFMERRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQLLAHRLKEAPQNQRNSSARLKALETELGEIKEAHEVTVRKLEAEISDLKHQNAALEHKKNDREDQDLQSLEFQVEQAHAKAKLARLNEELAAKGREIQDLSKTVERLQKERRMMLSRQGPRSREETSAKQVKKEVLHPSRGNANSFSGTLDAKLYHPHTFTDSHVSEVLQENYRLRKELEGLILERNKLKMDSEAAVYQFENSMKRVKDDTAAHIASLKASHQREMEKILCQNALENSSSKVAELNRKIITQEVLIKHFQGQVNELQGKQESLAVSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIKQMEMRHKQREQELQQIIQQTRQVVETEQNKEVEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPVALADEVNTAEF", "length": 1401, "header": "tr|A0A8C2MVK6-1|A0A8C2MVK6_CRIGR Computationally mapped isoform of Centrosomal protein of 162 kDa OS=Cricetulus griseus OX=10029 GN=Cep162 PE=3 SV=1 CANONICAL=A0A9J7FRB9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9/entry#A0A9J7FRB9-1", "sequence": { "sequence": "MFHFSKEELDEEFEQFMKELSDDSFESSNKTSKQPKKEMKKKDTVPWWITEDDFDDDLFLELLRTNVSYLKTKKTSQPIMDTEEESAEKAQFLKSSGTSILSVDSLEANELVLSELHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDSDDSTQFRALHSYLANTEPAEDGHESESEHEGLPETYSDDFEDAEDVDAPLITEKEETHPAENSESGRAHVPAQEEEKTGMLANVVLLDSLDSVEDVNLADQSKATPEAKALPEVTGGELTGTGVSYGQSSGDTEALHQAYCHIAHSLGDTGKPRIEASTVANAKSSVKDHLQENEESSKNISTTESDLPTVEELMKPIRIDSYGVSGFDLPPISLKKAADSKEGESVSSLLHKMNTNTVSQDPTHVNQFPYKHDENVTLHKTEGEIMGGGCPAATAMEERLDKMYLEILKKKTTVNPSLLPQDDKTNQTSRTQLSAGEEGPVTGKQVPYKKARSAPPLLKRKPQSGLYMSARSSGYGKPTSSLQLFSALEKKTSKDNTKSKNVRSIPTSNQFRKKEILSGTKLIKPAALNRPSPQSEGSLTTPKQPEDPTADSSVQFQTEPPGNGEKELLMLKRAQEAEEKWRGAQALIEQIKVTFSEKERELENTLETLKRQQEGELFKLNQENYILQTKLSSFEETSRKQRWLQLGETSDPITGEKLKQIQKEIEEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQNLFSELASLKEQVHKNRFLSQAVENAEPTKNQSFTDLLAELRVVQKEKNHLMEDIKRLKQDKQALEVDLEKVKKERDQAKDQIAYATGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDKDAARLREANEEAEKLKLEIEKLKTESGSPTTQQRLRSKERALDAKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSADRNTVEFMERRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQLLAHRLKEAPQNQRNSSARLKALETELGEIKEAHEVTVRKLEAEISDLKHQNAALEHKKNDREDQDLQSLEFQVEQAHAKAKLARLNEELAAKGREIQDLSKTVERLQKERRMMLSRQGPRSREETSAKQVKKEVLHPSRGNANSFSGTLDAKLYHPHTFTDSHVSEVLQENYRLRKELEGLILERNKLKMDSEAAVYQFENSMKRVKDDTAAHIASLKASHQREMEKILCQNALENSSSKVAELNRKIITQEVLIKHFQGQVNELQGKQESLAVSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIKQMEMRHKQREQELQQIIQQTRQVVETEQNKEVEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPVALADEVNTAEF", "length": 1405, "header": "tr|A0A9J7FRB9-1|A0A9J7FRB9_CRIGR Isoform 1 of Centrosomal protein of 162 kDa OS=Cricetulus griseus OX=10029 GN=Cep162 PE=3 SV=1 CANONICAL=A0A9J7FRB9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9/entry#A0A9J7GVM0-1", "sequence": { "sequence": "MDTEEESAEKAQFLKSSGTSILSVDSLEANELVLSELHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDSDDSTQFRALHSYLANTEPAEDGHESESEHEGLPETYSDDFEDAEDVDAPLITEKEETHPAENSESGRAHVPAQEEEKTGMLANVVLLDSLDSVEDVNLADQSKATPEAKALPEVTGGELTGTGVSYGQSSGDTEALHQAYCHIAHSLGDTGKPRIEASTVANAKSSVKDHLQENEESSKNISTTESDLPTVEELMKPIRIDSYGVSGFDLPPISLKKAADSKEGESVSSLLHKMNTNTVSQDPTHVNQFPYKHDENVTLHKTEGEIMGGGCPAATAMEERLDKMYLEILKKKTTVNPSLLPQDDKTNQTSRTQLSAGEEGPVTGKQVPYKKARSAPPLLKRKPQSGLYMSARSSGYGKPTSSLQLFSALEKKTSKDNTKSKNVRSIPTSNQFRKKEILSGTKLIKPAALNRPSPQSEGSLTTPKQPEDPTADSSVQFQTEPPGNGEKELLMLKRAQEAEEKWRGAQALIEQIKVTFSEKERELENTLETLKRQQEGELFKLNQENYILQTKLSSFEETSRKQRWLQLGETSDPITGEKLKQIQKEIEEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQNLFSELASLKEQVHKNRFLSQAVENAEPTKNQSFTDLLAELRVVQKEKNHLMEDIKRLKQDKQALEVDLEKVKKERDQAKDQIAYATGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDKDAARLREANEEAEKLKLEIEKLKTESGSPTTQQRLRSKERALDAKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSADRNTVEFMERRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQLLAHRLKEAPQNQRNSSARLKALETELGEIKEAHEVTVRKLEAEISDLKHQNAALEHKKNDREDQDLQSLEFQVEQAHAKAKLARLNEELAAKGREIQDLSKTVERLQKERRMMLSRQGPRSREETSAKQVKKEVLHPSRGNANSFSGTLDAKLYHPHTFTDSHVSEVLQENYRLRKELEGLILERNKLKMDSEAAVYQFENSMKRVKDDTAAHIASLKASHQREMEKILCQNALENSSSKVAELNRKIITQEVLIKHFQGQVNELQGKQESLAVSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIKQMEMRHKQREQELQQIIQQTRQVVETEQNKEVEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPVALADEVNTAEF", "length": 1326, "header": "tr|A0A9J7GVM0-1|A0A9J7GVM0_CRIGR Computationally mapped isoform of Centrosomal protein of 162 kDa OS=Cricetulus griseus OX=10029 GN=Cep162 PE=3 SV=1 CANONICAL=A0A9J7FRB9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JN90-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9/entry#A0A9J7JN90-1", "sequence": { "sequence": "MFHFSKEELDEEFEQFMKELSDDSFESSNKTSKQPKKEMKKKDTVPWWITEDDFDDDLFLELLRTNVSYLKTKKTSQPIMDTEEESAEKAQFLKSSGTSILSVDSLEANELVLSELHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDSDDSTQFRALHSYLANTEPAEDGHESESEHEGLPETYSDDFEDAEDVDAPLITEKEETHPAENSESGRAHVPAQEEEKTGMLANVVLLDSLDSVEDVNLADQSKATPEAKALPEVTGGELTGTGVSYGQSSGDTEALHQAYCHIAHSLGDTGKPRIEASTVANAKSSVKDHLQENEESSKNISTTESDLPTVEELMKPIRIDSYGVSGFDLPPISLKKAADSKEGESVSSLLHKMNTNTVSQDPTHVNQFPYKHDENVTLHKTEGEIMGGGCPAATAMEERLDKMYLEILKKKTTVNPSLLPQDDKTNQTSRTQLSAGEEGPVTGKQVPYKKARSAPPLLKRKPQSGLYMSARSSGYGKPTSSLQLFSALEKKTSKDNTKSKNVRSIPTSNQFRKKEILSGTKLIKPAALNRPSPQSEGSLTTPKQPEDPTADSSVQFQTEPPGNGEKELLMLKRAQEAEEKWRGAQALIEQIKVTFSEKERELENTLETLKRQQEGELFKLNQENYILQTKLSSFEETSRKQRWLQLGETSDPITGEKLKQIQKEIEEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQNLFSELASLKEQVHKNRFLSQAVENAEPTKNQSFTDLLAELRVVQKEKNHLMEDIKRLKQDKQALEVDLEKVKKERDQAKDQIAYATGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDKDAARLREANEEAEKLKLEIEKLKTESGSPTTQQRLRSKERALDAKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSADRNTVEFMERRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQLLAHRLKEAPQNQRNSSARLKALETELGEIKEAHEVTVRKLEAEISDLKHQNAALEHKKNDREDQDLQSLEFQVEQAHAKAKLARLNEELAAKGREIQDLSKTVERLQKERRMMLSRQGPRSREETSAKQVKKEVLHPSRGNANSFSGTLDAKLYHPHTFTDSHVSEVLQENYRLRKELEGLILERNKLKMDSEAAVYQFENSMKRYL", "length": 1214, "header": "tr|A0A9J7JN90-1|A0A9J7JN90_CRIGR Computationally mapped isoform of Centrosomal protein of 162 kDa OS=Cricetulus griseus OX=10029 GN=Cep162 PE=3 SV=1 CANONICAL=A0A9J7FRB9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 590, "start_aa": "Thr", "end_pos": 590, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr590", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRB9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRB9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759950", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759950", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRB9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRB9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRB9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRB9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRB9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1021, "end_pos": 1023, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1243, "end_pos": 1245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1306, "end_pos": 1308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 777, "end_pos": 779, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 590 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1021, "end_pos": 1023 }, { "start_pos": 1243, "end_pos": 1245 }, { "start_pos": 1306, "end_pos": 1308 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 467, "end_pos": 469 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 777, "end_pos": 779 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FRC5-1", "uniprot_ac": "A0A9J7FRC5", "uniprot_id": "A0A9J7FRC5_CRIGR", "mass": { "chemical_mass": 70916.0, "monoisotopic_mass": 70916.0 }, "refseq": { "ac": "XP_007649914", "name": "zinc finger protein 143 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649914" }, "gene_names": [ { "name": "Znf143", "type": "recommended", "evidence": [ { "id": "A0A9J7FRC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ] }, { "name": "Znf143", "type": "synonym", "evidence": [ { "id": "XP_007649914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649914" } ] } ], "protein_names": [ { "name": "Zinc finger protein 143", "type": "recommended", "evidence": [ { "id": "A0A9J7FRC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5/entry#names_and_taxonomy" } ] }, { "name": "Selenocysteine tRNA gene transcription-activating factor", "type": "synonym", "evidence": [ { "id": "A0A9J7FRC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 143 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007649914", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649914" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615051.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007649914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649914" } ] }, { "annotation": "Transcription factor that activates expression of genes transcribed by both RNA polymerases II and III, and which is required to safeguard mitochondrial activity. Specifically recognizes and binds the Staf-binding site (SBS), a consensus DNA-binding motif present in thousands of promoters. Activates the gene for selenocysteine tRNA (tRNAsec). Activates expression of small nuclear RNA (snRNA) transcribed by RNA polymerases II and III. Also activates expression of mRNAs and acts as a key regulator of cell proliferation and differentiation by specifically activating expression of a subset of nuclear-encoded mitochondrial genes, thereby controlling mitochondrial function. Involved in the maintenance of embryonic stem cells by promoting association of POU5F1/OCT4 to promoters, leading to NANOG expresion.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L662", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L662#function" }, { "database": "UniProtKB", "id": "ARBA00094347", "url": "https://www.uniprot.org/uniprotkb/ARBA00094347#function" }, { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5#function" }, { "database": "UniProtKB", "id": "A0A9J7FV79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV79#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf143", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5", "locus": {} } ], "crossref": [ { "id": "A0A9J7FRC5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FRC5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100752658", "url": "https://www.ncbi.nlm.nih.gov/gene/100752658", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752658", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752658", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FPALMHG", "url": "https://omabrowser.org/oma/group/FPALMHG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2L662", "url": "https://www.orthodb.org/?gene=A0A8C2L662", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FRC5", "url": "https://www.orthodb.org/?gene=A0A9J7FRC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FV79", "url": "https://www.orthodb.org/?gene=A0A9J7FV79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007649914", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649914", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2L662", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L662", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2L662-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L662-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVGRRNCWKIFSEKMLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSKDGRLIDGQVIQLEDGSAAYVQHVPIPKSTGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSSLQAVQLEDGTTAYIHHAVQVPQSDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSESVTSTGLIGENEQEKKMQIVLQGHATRVTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGDDVLKGSQITYVTGVEGEDIVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPTHDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHTASSEMGHQQHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "length": 653, "header": "tr|A0A9J7FRC5-1|A0A9J7FRC5_CRIGR Isoform 1 of Zinc finger protein 143 OS=Cricetulus griseus OX=10029 GN=Znf143 PE=3 SV=1 CANONICAL=A0A9J7FRC5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2L662-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5/entry#A0A8C2L662-1", "sequence": { "sequence": "MLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSKDGRLIDGQVIQLEDGSAAYVQHVPIPKSTGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSSLQAVQLEDGTTAYIHHAVQVPQSDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSESVTSTGLIGENEQEKKMQIVLQGHATRVTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGDDVLKGSQITYVTGVEGEDIVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPTHDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHTASSEMGHQQHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "length": 638, "header": "tr|A0A8C2L662-1|A0A8C2L662_CRIGR Computationally mapped isoform of Zinc finger protein 143 OS=Cricetulus griseus OX=10029 GN=Znf143 PE=3 SV=1 CANONICAL=A0A9J7FRC5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5/entry#A0A9J7FRC5-1", "sequence": { "sequence": "MVVGRRNCWKIFSEKMLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSKDGRLIDGQVIQLEDGSAAYVQHVPIPKSTGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSSLQAVQLEDGTTAYIHHAVQVPQSDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSESVTSTGLIGENEQEKKMQIVLQGHATRVTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGDDVLKGSQITYVTGVEGEDIVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPTHDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHTASSEMGHQQHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "length": 653, "header": "tr|A0A9J7FRC5-1|A0A9J7FRC5_CRIGR Isoform 1 of Zinc finger protein 143 OS=Cricetulus griseus OX=10029 GN=Znf143 PE=3 SV=1 CANONICAL=A0A9J7FRC5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FV79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5/entry#A0A9J7FV79-1", "sequence": { "sequence": "MVVGRRNCWKIFSEKMLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSKDGRLIDGQVIQLEDGSAAYVQHVPIPKSRDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSSLQAVQLEDGTTAYIHHAVQVPQSDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSESVTSTGLIGENEQEKKMQIVLQGHATRVTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGDDVLKGSQITYVTGVEGEDIVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPTHDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHTASSEMGHQQHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "length": 652, "header": "tr|A0A9J7FV79-1|A0A9J7FV79_CRIGR Computationally mapped isoform of Zinc finger protein 143 OS=Cricetulus griseus OX=10029 GN=Znf143 PE=3 SV=1 CANONICAL=A0A9J7FRC5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752658", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752658", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QTH5-1", "protein_name": "Zinc finger protein 143", "gene_name": "ZNF143", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLLAQINRDSQGMTEFPGGGMETQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHSSKDGKLIDGQVIQLEDGSAAYVQHVPIPKSTGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSALQAVQLEDGTTAYIHHAVQVPQSDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSESVTGSGMIGENEQEKKMQIVLQGHATRVTAKSQQSGEKAFRCGYDGCGKLYTTGHHLKVHERSHTGDRPYQCEHAGCGKAFATGYGLKSHVRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCHFEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQSEDVLKGSQITYVTGVEGDDVVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPAQDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHAASSEMGHQQHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "length": 638 }, "evidence": [ { "id": "A0A9J7FRC5", "url": "https://omabrowser.org/oma/group/A0A9J7FRC5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1C5B8-1", "protein_name": "Zinc finger protein 143", "gene_name": "ZNF143", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLLAQINRDSQGMTEFSGGGMEAQHVTLCLTEAVAVQDGDNLENMEGVSLQAVTLADGSTAYIQHNSKDGKLMDGQVIQLEDGSAAYVQHVPMTKSRDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSALQAVQLEDGTTAYIHHAVQMPQSDTILAIQADGTVAGLHTGDAAIDPDTITALEQYAAKVSIDGNDSVSSTGMIGENEQEKKMQIVLQGHGTRVAAKSQQSGEKAFRCDYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHPGCGKAFATGYGLKSHIRTHTGEKPYRCTEENCTKSFKTSGDLQKHIRTHTGERPFKCPFEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGEDVLKGSQIAYVTGVEGEDVISAQVATVTQSGLGQQVALISQDGTQHVNISQADMQAIGNTITMVTQDGTTITVPAHDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHSTSPEIGHQQHGHHLVTTEARPVTLLATSNGTQIAVQLGEQQSLEEAIRIASRIQQGETPGIDD", "length": 637 }, "evidence": [ { "id": "A0A9J7FRC5", "url": "https://omabrowser.org/oma/group/A0A9J7FRC5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O70230-1", "protein_name": "Zinc finger protein 143", "gene_name": "Znf143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSKDGRLIDGQVIQLEDGSAAYVQHVPIPKSTGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSSLQAVQLEDGTTAYIHHAVQVPQSDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSDGVTSTGMIGENEQEKKMQIVLQGHATRVTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGDDVLKGSQITYVTGVDGEDIVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPTHDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHTASSEMGHQQHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "length": 638 }, "evidence": [ { "id": "A0A9J7FRC5", "url": "https://omabrowser.org/oma/group/A0A9J7FRC5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P52747-1", "protein_name": "Zinc finger protein 143", "gene_name": "ZNF143", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSKDAKLIDGQVIQLEDGSAAYVQHVPIPKSTGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSALQAVQLEDGTTAYIHHAVQVPQSDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSESVAGTGMIGENEQEKKMQIVLQGHATRVTAKSQQSGEKAFRCEYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHAGCGKAFATGYGLKSHVRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPFEGCGRSFTTSNIRKVHVRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGEDVLKGSQITYVTGVEGDDVVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPAHDAVISSAGTHSVAMVTAEGTEGEQVAIVAQDLAAFHTASSEMGHQQHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "length": 638 }, "evidence": [ { "id": "A0A9J7FRC5", "url": "https://omabrowser.org/oma/group/A0A9J7FRC5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYE3-1", "protein_name": "Zinc finger protein 143B", "gene_name": "znf143b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLAQVNRDTQGMEFQSVDGDPQQVTLCLTEAVTVADDNIDGMDTVSLQAVTLVDGSTAYIQHSPKVSLTENKIMEGQVIQLEDGSAAYVQHLPMSKTGGEGLRLEDGQAVQLEDGTTAYIHAPKETYDQGGLQAVQLEDGTTAYIQHMPQSNTILAIQADGTVADLQTEGTIDAETISVLEQYSTKMEATECGTGLIGRGDSDGVHMQIVLQGQDCRSPRIQHVGEKAFRCEHEGCGKLYTTAHHLKVHERSHTGDKPYICDHLGCGKKFATGYGLKSHVRTHTGEKPYRCQELNCLKSFKTSGDLQKHTRTHTGEKPFKCPFEGCGRSFTTSNIRKVHIRTHTGERPYYCAEPNCGRAFASATNYKNHMRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTPCKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEGYFEPPAEAIDDPGLMYTPSVVDDDSGSEQVSGSEIMGQHHVALISQDGTQQVLSQADMQAMGGTITMVTQEGTTITIPAHEAMLSSGGAHSVTMVSADGTEGQVAIVTPDLAAYQTEEGELIQDQEQHEVSTSPHPVTLLATSNGTHIAVQLSDHPSLEEAIRIASRIQQGETPGMDD", "length": 623 }, "evidence": [ { "id": "A0A9J7FRC5", "url": "https://omabrowser.org/oma/group/A0A9J7FRC5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5XIU2-1", "protein_name": "Zinc finger protein 143", "gene_name": "Znf143", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLAQINRDSQGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEGVSLQAVTLADGSTAYIQHNSKDGRLIDGQVIQLEDGSAAYVQHVPIPKSTGDSLRLEDGQAVQLEDGTTAFIHHTSKDSYDQSSLQAVQLEDGTTAYIHHAVQVPQPDTILAIQADGTVAGLHTGDATIDPDTISALEQYAAKVSIDGSEGVTSTGLIGENEQEKKMQIVLQGHATRVTPKSQQSGEKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYRCSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPGCGRAFASATNYKNHVRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTHSKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEAFFEPPPGQGDDVLKGSQITYVTGVEGEDIVSTQVATVTQSGLSQQVTLISQDGTQHVNISQADMQAIGNTITMVTQDGTPITVPTHDAVISSAGTHSVAMVTAEGTEGQQVAIVAQDLAAFHAASSEMGHQPHSHHLVTTETRPLTLVATSNGTQIAVQLGEQPSLEEAIRIASRIQQGETPGLDD", "length": 638 }, "evidence": [ { "id": "A0A9J7FRC5", "url": "https://omabrowser.org/oma/group/A0A9J7FRC5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" }, { "name": "core promoter sequence-specific DNA binding", "id": "GO:0001046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001046", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" }, { "name": "transcription regulator activator activity", "id": "GO:0140537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140537", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FRC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 252, "end_pos": 281, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 318, "end_pos": 320 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 525, "end_pos": 527 }, { "start_pos": 619, "end_pos": 621 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FRC8-1", "uniprot_ac": "A0A9J7FRC8", "uniprot_id": "A0A9J7FRC8_CRIGR", "mass": { "chemical_mass": 75860.0, "monoisotopic_mass": 75860.0 }, "refseq": { "ac": "XP_027263563", "name": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263563" }, "gene_names": [ { "name": "Rnf169", "type": "recommended", "evidence": [ { "id": "A0A9J7FRC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC8" } ] }, { "name": "Rnf169", "type": "synonym", "evidence": [ { "id": "XP_027263563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263563" } ] } ], "protein_names": [ { "name": "RING-type E3 ubiquitin transferase", "type": "recommended", "evidence": [ { "id": "A0A9J7FRC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC8/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A9J7FRC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC8/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027263563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263563" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263563" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rnf169", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC8", "locus": {} } ], "crossref": [ { "id": "cd16551", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16551", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756964", "url": "https://www.ncbi.nlm.nih.gov/gene/100756964", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756964", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756964", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FRC8", "url": "https://www.orthodb.org/?gene=A0A9J7FRC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23328:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23328:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_027263563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FRC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"MALRTRIHDLPFYTRAVAILLETKADSRAHHSGTEGELCISFQDLADELALIDADADKLKGETMDLLHGSLFFNTPKIVSGKDYNVSANSKLVIITAGARQKVGETRLDLVQRNVVIMKSIIPGIVQNSPDCKILIVSNPVDILTYVAWKISGLPATRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWILGEHGDSSVPLWSGVNVAGVLLKSLNPALGTDSDQEHWKKIHNQVVESGYEVLRLKGYTSWAIGLSVTDLAGSMLKNLRRVHPVSTLVKGLYGIQEEIFLSVPCILGRNGVTDIVKVNLNPEEEGLLKKSAETLWNVQKDLKL", "length": 333, "header": "tr|A0A9J7FRD1-1|A0A9J7FRD1_CRIGR Isoform 1 of L-lactate dehydrogenase OS=Cricetulus griseus OX=10029 GN=LOC100751672 PE=3 SV=1 CANONICAL=A0A9J7FRD1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1/entry#A0A9J7FRD1-1", "sequence": { "sequence": "MALRTRIHDLPFYTRAVAILLETKADSRAHHSGTEGELCISFQDLADELALIDADADKLKGETMDLLHGSLFFNTPKIVSGKDYNVSANSKLVIITAGARQKVGETRLDLVQRNVVIMKSIIPGIVQNSPDCKILIVSNPVDILTYVAWKISGLPATRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWILGEHGDSSVPLWSGVNVAGVLLKSLNPALGTDSDQEHWKKIHNQVVESGYEVLRLKGYTSWAIGLSVTDLAGSMLKNLRRVHPVSTLVKGLYGIQEEIFLSVPCILGRNGVTDIVKVNLNPEEEGLLKKSAETLWNVQKDLKL", "length": 333, "header": "tr|A0A9J7FRD1-1|A0A9J7FRD1_CRIGR Isoform 1 of L-lactate dehydrogenase OS=Cricetulus griseus OX=10029 GN=LOC100751672 PE=3 SV=1 CANONICAL=A0A9J7FRD1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JEZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1/entry#A0A9J7JEZ0-1", "sequence": { "sequence": "MALRTRIHDLPFYTRAVAILLETKADSRAHHSGTEGELCISFQDLADELALIDADADKLKGETMDLLHGSLFFNTPKIVSGKVDILTYVAWKISGLPATRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWILGEHGDSSVPLWSGVNVAGVLLKSLNPALGTDSDQEHWKKIHNQVVESGYEVLRLKGYTSWAIGLSVTDLAGSMLKNLRRVHPVSTLVKGLYGIQEEIFLSVPCILGRNGVTDIVKVNLNPEEEGLLKKSAETLWNVQKDLKL", "length": 275, "header": "tr|A0A9J7JEZ0-1|A0A9J7JEZ0_CRIGR Computationally mapped isoform of L-lactate dehydrogenase OS=Cricetulus griseus OX=10029 GN=LOC100751672 PE=3 SV=1 CANONICAL=A0A9J7FRD1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K720-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1/entry#A0A9J7K720-1", "sequence": { "sequence": "MDLLHGSLFFNTPKIVSGKDYNVSANSKLVIITAGARQKVGETRLDLVQRNVVIMKSIIPGIVQNSPDCKILIVSNPVDILTYVAWKISGLPATRVIGSGCNLDSARFRYLIGEKLGVHPTSCHGWILGEHGDSSVPLWSGVNVAGVLLKSLNPALGTDSDQEHWKKIHNQVVESGYEVLRLKGYTSWAIGLSVTDLAGSMLKNLRRVHPVSTLVKGLYGIQEEIFLSVPCILGRNGVTDIVKVNLNPEEEGLLKKSAETLWNVQKDLKL", "length": 270, "header": "tr|A0A9J7K720-1|A0A9J7K720_CRIGR Computationally mapped isoform of L-lactate dehydrogenase OS=Cricetulus griseus OX=10029 GN=LOC100751672 PE=3 SV=1 CANONICAL=A0A9J7FRD1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751672", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751672", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "L-lactate dehydrogenase (NAD+) activity", "id": "GO:0004459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004459", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lactate metabolic process", "id": "GO:0006089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006089", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRD1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23444", "name": "", "equation": "(S)-lactate + NAD(+) = pyruvate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3HH14-1", "G3HFW4-1", "A0A9J7FRD1-1" ], "evidence": [ { "id": "23444", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23444" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7FRD1", "gene_name": "LOC100751672", "activity": [ { "ec_number": "1.1.1.27", "activity": "(S)-lactate + NAD(+) = pyruvate + NADH + H(+).", "evidence": [ { "id": "A0A9J7FRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1" } ] }, { "ec_number": "1.1.1.27", "activity": "", "evidence": [ { "id": "A0A9J7FRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1" } ] } ] }, { "uniprot_ac": "G3HFW4", "gene_name": "LOC100770821", "activity": [ { "ec_number": "1.1.1.27", "activity": "(S)-lactate + NAD(+) = pyruvate + NADH + H(+).", "evidence": [ { "id": "G3HFW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HFW4" } ] }, { "ec_number": "1.1.1.27", "activity": "", "evidence": [ { "id": "G3HFW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HFW4" } ] } ] }, { "uniprot_ac": "G3HH14", "gene_name": "Ldhb", "activity": [ { "ec_number": "1.1.1.27", "activity": "(S)-lactate + NAD(+) = pyruvate + NADH + H(+).", "evidence": [ { "id": "G3HH14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HH14" } ] }, { "ec_number": "1.1.1.27", "activity": "", "evidence": [ { "id": "G3HH14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HH14" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1" }, { "id": "PF02866", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02866" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lactate/malate dehydrogenase C-terminal", "eco_id": "ECO_0000259", "start_pos": 165, "end_pos": 327, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRD1" }, { "id": "PF00056", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lactate/malate dehydrogenase N-terminal", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 161, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.27", "ec_name": "(S)-lactate + NAD(+) = pyruvate + NADH + H(+).", "evidence": [ { "id": "1.1.1.27", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.27" }, { "id": "1.1.1.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FRE7-1", "uniprot_ac": "A0A9J7FRE7", "uniprot_id": "A0A9J7FRE7_CRIGR", "mass": { "chemical_mass": 45639.0, "monoisotopic_mass": 45639.0 }, "refseq": { "ac": "XP_027264403", "name": "LOW QUALITY PROTEIN: sorting nexin-32 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264403" }, "gene_names": [ { "name": "Snx32", "type": "recommended", "evidence": [ { "id": "A0A9J7FRE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7" } ] }, { "name": "Snx32", "type": "synonym", "evidence": [ { "id": "XP_027264403", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264403" } ] } ], "protein_names": [ { "name": "Sorting nexin", "type": "recommended", "evidence": [ { "id": "A0A9J7FRE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: sorting nexin-32 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027264403", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264403" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases frameshifts :: corrected 3 indels internal stop codons :: corrected 6 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264403" } ] }, { "annotation": "Involved in several stages of intracellular trafficking.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7#function" }, { "database": "UniProtKB", "id": "PIRNR036924", "url": "https://www.uniprot.org/uniprotkb/PIRNR036924#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Snx32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7", "locus": {} } ], "crossref": [ { "id": "cd06892", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06892", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107977948", "url": "https://www.ncbi.nlm.nih.gov/gene/107977948", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:107977948", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107977948", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FRE7", "url": "https://www.orthodb.org/?gene=A0A9J7FRE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45850", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45850", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45850:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45850:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027264403", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264403", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FRE7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLDLQGDSSLQVEISDAVSEWDKVKFTVQTKSGLPHFAHLEFSVVRQHKEFIWLHDTYVGNEEYAGLILRRDSPTPPRPDFEASRAKLQKLGEDNSSTTQEEFAKMKQELEAXYLAIFKKTVAMHEVFLQHLAAHPVLHQDHFFVFLEFSQSQALSVXEKNRKEVLGGFLRSIVKSANEVLITGITGLKVTFCLGQGKPLDHHTRIXGTCQRANRVMHSRKCLADELCTAALSSLGTREVSQLKRSFLNLAELFKXLRKLEGRVISDEHLKLSACXDTTMQDSQAARMRGPAVQVLQTLADSENANKALDKACKRSRXVQPAESHQKLCCQRFEHLSDFAKQELMDXRSNRVSSFSFEWAELELKQAKVSTHCPFLHVLSCCSHLLXPIKGGGRGDGEAAVYSQA", "length": 406, "header": "tr|A0A9J7FRE7-1|A0A9J7FRE7_CRIGR Isoform 1 of Sorting nexin OS=Cricetulus griseus OX=10029 GN=Snx32 PE=3 SV=1 CANONICAL=A0A9J7FRE7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7/entry#A0A9J7FRE7-1", "sequence": { "sequence": "MLLDLQGDSSLQVEISDAVSEWDKVKFTVQTKSGLPHFAHLEFSVVRQHKEFIWLHDTYVGNEEYAGLILRRDSPTPPRPDFEASRAKLQKLGEDNSSTTQEEFAKMKQELEAXYLAIFKKTVAMHEVFLQHLAAHPVLHQDHFFVFLEFSQSQALSVXEKNRKEVLGGFLRSIVKSANEVLITGITGLKVTFCLGQGKPLDHHTRIXGTCQRANRVMHSRKCLADELCTAALSSLGTREVSQLKRSFLNLAELFKXLRKLEGRVISDEHLKLSACXDTTMQDSQAARMRGPAVQVLQTLADSENANKALDKACKRSRXVQPAESHQKLCCQRFEHLSDFAKQELMDXRSNRVSSFSFEWAELELKQAKVSTHCPFLHVLSCCSHLLXPIKGGGRGDGEAAVYSQA", "length": 406, "header": "tr|A0A9J7FRE7-1|A0A9J7FRE7_CRIGR Isoform 1 of Sorting nexin OS=Cricetulus griseus OX=10029 GN=Snx32 PE=3 SV=1 CANONICAL=A0A9J7FRE7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 76, "start_aa": "Thr", "end_pos": 76, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr76", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:107977948", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107977948", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FRE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE7" }, { "id": "PF00787", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 150, "start_aa": "His", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 76 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FRH4-1", "uniprot_ac": "A0A9J7FRH4", "uniprot_id": "A0A9J7FRH4_CRIGR", "mass": { "chemical_mass": 62384.0, "monoisotopic_mass": 62384.0 }, "refseq": { "ac": "XP_027266913", "name": "leucine-rich repeat-containing protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266913" }, "gene_names": [ { "name": "Lrrc1", "type": "recommended", "evidence": [ { "id": "A0A9J7FRH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ] }, { "name": "Lrrc1", "type": "synonym", "evidence": [ { "id": "XP_027266913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266913" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7FRH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027266913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266913" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266913" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrrc1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4", "locus": {} } ], "crossref": [ { "id": "A0A9J7FRH4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FRH4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751156", "url": "https://www.ncbi.nlm.nih.gov/gene/100751156", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751156", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751156", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FRH4", "url": "https://www.orthodb.org/?gene=A0A9J7FRH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23119:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23119:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LKE7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LKE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFHCIPLWRCNRHVEVIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNGKKTSHLECPLDSLDAGGMINKKRVYKDIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKSLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCNLTVFCVRNNRLTRIPSEVSQAMELHVLDVAGNRLRHLPLSLTTLKLKALWLSDNQSQPLLTFQTDTDHTTGEKILTCVLLPQMPSEPICQESLSRCGALESLVSDISEDAWNDRTVHRVSAIRFLEDEKDEEENETRTLQRRATPHPGELKNMKKSVENLRNDMNAAKGLDSNKNEVNHTPDRVTTSV", "length": 551, "header": "tr|A0A9J7FRH4-1|A0A9J7FRH4_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Lrrc1 PE=4 SV=1 CANONICAL=A0A9J7FRH4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LKE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4/entry#A0A8C2LKE7-1", "sequence": { "sequence": "MFHCIPLWRCNRHVEVIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNDIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKSLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCNLTVFCVRNNRLTRIPSEVSQAMELHVLDVAGNRLRHLPLSLTTLKLKALWLSDNQSQPLLTFQTDTDHTTGEKILTCVLLPQMPSEPICQESLSRCGALESLVSDISEDAWNDRTVHRVSAIRFLEDEKDEEENETRTLQRRATPHPGELKNMKKSVENLRNDMNAAKGLDSNKNEVNHTPDRVTTSV", "length": 524, "header": "tr|A0A8C2LKE7-1|A0A8C2LKE7_CRIGR Computationally mapped isoform of Leucine-rich repeat-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Lrrc1 PE=4 SV=1 CANONICAL=A0A9J7FRH4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4/entry#A0A9J7FRH4-1", "sequence": { "sequence": "MFHCIPLWRCNRHVEVIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNGKKTSHLECPLDSLDAGGMINKKRVYKDIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKSLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCNLTVFCVRNNRLTRIPSEVSQAMELHVLDVAGNRLRHLPLSLTTLKLKALWLSDNQSQPLLTFQTDTDHTTGEKILTCVLLPQMPSEPICQESLSRCGALESLVSDISEDAWNDRTVHRVSAIRFLEDEKDEEENETRTLQRRATPHPGELKNMKKSVENLRNDMNAAKGLDSNKNEVNHTPDRVTTSV", "length": 551, "header": "tr|A0A9J7FRH4-1|A0A9J7FRH4_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Lrrc1 PE=4 SV=1 CANONICAL=A0A9J7FRH4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4/entry#A0A9J7FVW9-1", "sequence": { "sequence": "MFHCIPLWRCNRHVEVIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNGKKTSHLECPLDSLDAGGMINKKRVYKDIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKSLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCNLTVFCVRNNRLTRIPSEVSQAMELHVLDVAGNRLRHLPLSLTTLKLKALWLSDNQSQPLLTFQTDTDHTTGEKILTCVLLPQMPSEPICQESLSRCGALESLVSDISEDAWNDRTVHRVSAIRFLEDEKDEEENETERLGWNGSGGKSSFKTLILKGNAWRRRSC", "length": 528, "header": "tr|A0A9J7FVW9-1|A0A9J7FVW9_CRIGR Computationally mapped isoform of Leucine-rich repeat-containing protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Lrrc1 PE=4 SV=1 CANONICAL=A0A9J7FRH4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751156", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751156", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "neurotransmitter receptor transport, endosome to postsynaptic membrane", "id": "GO:0098887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" }, { "name": "receptor clustering", "id": "GO:0043113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043113", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" }, { "name": "neurotransmitter receptor transport postsynaptic membrane to endosome", "id": "GO:0098968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098968", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" }, { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FRH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRH4" }, { "id": "PF23598", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Disease resistance R13L4/SHOC-2-like LRR", "eco_id": "ECO_0000259", "start_pos": 218, "end_pos": 300, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 541, "end_pos": 543 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"XP_027266624", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266624" } ] } ], "protein_names": [ { "name": "Piwi-like protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7FRJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5/entry#names_and_taxonomy" } ] }, { "name": "piwi-like protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027266624", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266624" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266624", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266624" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Piwil4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5", "locus": {} } ], "crossref": [ { "id": "A0A9J7FRJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FRJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02845", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02845", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04658", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04658", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754528", "url": "https://www.ncbi.nlm.nih.gov/gene/100754528", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014811", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014811", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754528", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754528", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FRJ5", "url": "https://www.orthodb.org/?gene=A0A9J7FRJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22891", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22891", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23278", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23278", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266624", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266624", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY85", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY85-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H135", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H135", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H135-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H135-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGRARVRARGIIPGHGAREVGCAPGDLTASSIASPGDSQALSSGTSSISQPPNTGISNDDGGRTFTERGKVRRDVIDLSVCTREKLAHVKDCKAGSSGIPLQLVTNLFSLDLPQDWQLYQYHVTYSPDLASRRLRIALLYSHSKLLDKAKAFDGTILFLSEKLDLKVTELTSETQRGETVTITLTLTTQLSSSSPVCIQFFSVIFRKIFKKLKMYQIGRNFYKPSEPVEIPQYKLSLWPGFAVSVSRFESRLLLNADVSYKVLRNETVLEFMTDLCLRTGMSHFTETCQKQLVGLIVLTRYNNKTYRIDDIDWSVKPTHAFQKRDGSEITYMDYYKQQYNITLSDLNQPVLVSLLKRKRKDSSEPQMVHLVPELCFLTGLSSQATSDFHLMKAVAEETRLSPVGRQQQLARLVDDIQRNQVARLELETWGLHFGSQISLTGRVVPSEKILLQDHTCQPATAADWSKDMRTCKILSSQPLSRWLIVCCNRAENLIEGLMSCLRRVGGPMGFNVGYPKIIKVDEKPAAFLRAIQLHVNPDVQLVMCILPSNPKNYYDSIKKYLSSDCPVPSQCVLTRTLTKQGMMMSVATKIAMQMTCKLGGELWAVEIPLKSLMVAGIDICRDALNKDVVVVGFVASINSRITRWFSRCVLQRTAADIADCLKVCLTGALNKWYKHNHDLPSRIIIYRDGVGDGQLKTVLDYEVPQLLSSVTECSSGASSSRLSVVVVRKRCLLRFFTETGHTVQNPPLGTVVDSEATRAEWYDFYLVSQTANRGTVSPTYYNIIYDDNGLKPDHMQRLTFKLCHLYYNWQGLISVPAPCQYAHKLTFLVAQSIHKEPSLELSDNLFYL", "length": 849, "header": "tr|A0A9J7FRJ5-1|A0A9J7FRJ5_CRIGR Isoform 1 of Piwi-like protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Piwil4 PE=3 SV=1 CANONICAL=A0A9J7FRJ5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5/entry#A0A9J7FRJ5-1", "sequence": { "sequence": "MSGRARVRARGIIPGHGAREVGCAPGDLTASSIASPGDSQALSSGTSSISQPPNTGISNDDGGRTFTERGKVRRDVIDLSVCTREKLAHVKDCKAGSSGIPLQLVTNLFSLDLPQDWQLYQYHVTYSPDLASRRLRIALLYSHSKLLDKAKAFDGTILFLSEKLDLKVTELTSETQRGETVTITLTLTTQLSSSSPVCIQFFSVIFRKIFKKLKMYQIGRNFYKPSEPVEIPQYKLSLWPGFAVSVSRFESRLLLNADVSYKVLRNETVLEFMTDLCLRTGMSHFTETCQKQLVGLIVLTRYNNKTYRIDDIDWSVKPTHAFQKRDGSEITYMDYYKQQYNITLSDLNQPVLVSLLKRKRKDSSEPQMVHLVPELCFLTGLSSQATSDFHLMKAVAEETRLSPVGRQQQLARLVDDIQRNQVARLELETWGLHFGSQISLTGRVVPSEKILLQDHTCQPATAADWSKDMRTCKILSSQPLSRWLIVCCNRAENLIEGLMSCLRRVGGPMGFNVGYPKIIKVDEKPAAFLRAIQLHVNPDVQLVMCILPSNPKNYYDSIKKYLSSDCPVPSQCVLTRTLTKQGMMMSVATKIAMQMTCKLGGELWAVEIPLKSLMVAGIDICRDALNKDVVVVGFVASINSRITRWFSRCVLQRTAADIADCLKVCLTGALNKWYKHNHDLPSRIIIYRDGVGDGQLKTVLDYEVPQLLSSVTECSSGASSSRLSVVVVRKRCLLRFFTETGHTVQNPPLGTVVDSEATRAEWYDFYLVSQTANRGTVSPTYYNIIYDDNGLKPDHMQRLTFKLCHLYYNWQGLISVPAPCQYAHKLTFLVAQSIHKEPSLELSDNLFYL", "length": 849, "header": "tr|A0A9J7FRJ5-1|A0A9J7FRJ5_CRIGR Isoform 1 of Piwi-like protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Piwil4 PE=3 SV=1 CANONICAL=A0A9J7FRJ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GY85-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5/entry#A0A9J7GY85-1", "sequence": { "sequence": "MSGRARVRARGIIPGHGAREVGCAPGDLTVSVSPSNTGISNDDGGRTFTERGKVRRDVIDLSVCTREKLAHVKDCKAGSSGIPLQLVTNLFSLDLPQDWQLYQYHVTYSPDLASRRLRIALLYSHSKLLDKAKAFDGTILFLSEKLDLKVTELTSETQRGETVTITLTLTTQLSSSSPVCIQFFSVIFRKIFKKLKMYQIGRNFYKPSEPVEIPQYKLSLWPGFAVSVSRFESRLLLNADVSYKVLRNETVLEFMTDLCLRTGMSHFTETCQKQLVGLIVLTRYNNKTYRIDDIDWSVKPTHAFQKRDGSEITYMDYYKQQYNITLSDLNQPVLVSLLKRKRKDSSEPQMVHLVPELCFLTGLSSQATSDFHLMKAVAEETRLSPVGRQQQLARLVDDIQRNQVARLELETWGLHFGSQISLTGRVVPSEKILLQDHTCQPATAADWSKDMRTCKILSSQPLSRWLIVCCNRAENLIEGLMSCLRRVGGPMGFNVGYPKIIKVDEKPAAFLRAIQLHVNPDVQLVMCILPSNPKNYYDSIKKYLSSDCPVPSQCVLTRTLTKQGMMMSVATKIAMQMTCKLGGELWAVEIPLKSLMVAGIDICRDALNKDVVVVGFVASINSRITRWFSRCVLQRTAADIADCLKVCLTGALNKWYKHNHDLPSRIIIYRDGVGDGQLKTVLDYEVPQLLSSVTECSSGASSSRLSVVVVRKRCLLRFFTETGHTVQNPPLGTVVDSEATRAEWYDFYLVSQTANRGTVSPTYYNIIYDDNGLKPDHMQRLTFKLCHLYYNWQGLISVPAPCQYAHKLTFLVAQSIHKEPSLELSDNLFYL", "length": 831, "header": "tr|A0A9J7GY85-1|A0A9J7GY85_CRIGR Computationally mapped isoform of Piwi-like protein 4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Piwil4 PE=3 SV=1 CANONICAL=A0A9J7FRJ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H135-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5/entry#A0A9J7H135-1", "sequence": { "sequence": "MSGRARVRARGIIPGHGAREVGCAPGDLTASSIASPGDSQALSSGTSSISQPPNTGISNDDGGRTFTERGKVRRDVIDLSVCTREKLAHVKDCKAGSSGIPLQLVTNLFSLDLPQDWQLYQYHVTYSPDLASRRLRIALLYSHSKLLDKAKAFDGTILFLSEKLDLKVTELTSETQRGETVTITLTLTTQLSSSSPVCIQFFSVIFRKIFKKLKMYQIGRNFYKPSEPVEIPQYKLSLWPGFAVSVSRFESRLLLNADVSYKVLRNETVLEFMTDLCLRTGMSHFTETCQKQLVGLIVLTRYNNKTYRIDDIDWSVKPTHAFQKRDGSEITYMDYYKQQYNITLSDLNQPVLVSLLKRKRKDSSEPQMVHLVPELCFLTGLSSQATSDFHLMKAVAEETRLSPVGRQQQLARLVDDIQRNQVARLELETWGLHFGSQISLTGRVVPSEKILLQDHTCQPATAADWSKDMRTCKILSSQPLSRWLIVCCNRAENLIEGLMSCLRRVGGPMGFNVGYPKIIKVDEKPAAFLRAIQLHVNPDVQLVMCILPSNPKNYYDSIKKYLSSDCPVPSQCVLTRTLTKQGMMMSVATKIAMQMTCKLGGELWAVEIPLKSLMVAGIDICRDALNKDVVVVGFVASINSRITRWFSRCVLQRTAADIADCLKVCLTGALNKWYKHNHDLPSRIIIYRDGVGDGQLKTVLDYEVPQLLSSVTECSSGASSSRLSVVVVRKRCLLRFFTETGHTVQNPPLGTVVDSEATRAEYDFYLVSQTANRGTVSPTYYNIIYDDNGLKPDHMQRLTFKLCHLYYNWQGLISVPAPCQYAHKLTFLVAQSIHKEPSLELSDNLFYL", "length": 848, "header": "tr|A0A9J7H135-1|A0A9J7H135_CRIGR Computationally mapped isoform of Piwi-like protein 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Piwil4 PE=3 SV=1 CANONICAL=A0A9J7FRJ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754528", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754528", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" } ], "pmid": "" }, { "name": "regulatory ncRNA-mediated gene silencing", "id": "GO:0031047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031047", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FRJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" }, { "id": "PS50821", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50821" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PAZ", "eco_id": "ECO_0000259", "start_pos": 268, "end_pos": 380, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FRJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRJ5" }, { "id": "PS50822", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50822" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Piwi", "eco_id": "ECO_0000259", "start_pos": 542, "end_pos": 835, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 341, "end_pos": 343 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FRK3-1", "uniprot_ac": "A0A9J7FRK3", "uniprot_id": "A0A9J7FRK3_CRIGR", "mass": { "chemical_mass": 40139.0, "monoisotopic_mass": 40139.0 }, "refseq": { "ac": "XP_027263301", "name": "olfactory receptor 52B4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263301" }, "gene_names": [ { "name": "LOC100754870", "type": "recommended", "evidence": [ { "id": "A0A9J7FRK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK3" } ] }, { "name": "LOC100754870", "type": "synonym", "evidence": [ { "id": "XP_027263301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263301" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7FRK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 52B4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027263301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263301" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 13% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. 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"UniProtKB", "id": "A0A9J7FRK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FRK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FRK9-1", "uniprot_ac": "A0A9J7FRK9", "uniprot_id": "A0A9J7FRK9_CRIGR", "mass": { "chemical_mass": 36425.0, "monoisotopic_mass": 36425.0 }, "refseq": { "ac": "XP_027263318", "name": "olfactory receptor 51M1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263318" }, "gene_names": [ { "name": "LOC100773549", "type": "recommended", "evidence": [ { "id": "A0A9J7FRK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK9" } ] }, { "name": "LOC100773549", "type": "synonym", "evidence": [ { "id": "XP_027263318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263318" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7FRK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 51M1", "type": "synonym", "evidence": [ { "id": "XP_027263318", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263318" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263318", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263318" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773549", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK9", "locus": {} } ], "crossref": [ { "id": "A0A9J7FRK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FRK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15222", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15222", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773549", "url": "https://www.ncbi.nlm.nih.gov/gene/100773549", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773549", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773549", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FRK9", "url": "https://www.orthodb.org/?gene=A0A9J7FRK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027263318", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263318", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FRK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLSNITHFSPMFYLSSFPGLEAFKHWIFIPFFLMYLVAISGNCLILMIIKTSPRLHTPMYYLLSLLALTDLGLSMSTLPTTVGIFWFNYHSIYFGACQIQMFCIHSFSFMESAVLLVMSFDRYVAICHPLRYSVIITGERVIRIGLCVILRGPVALIPIVLLLKAFPYCGPLVLSHSFCLHQEVIHLACVDTTFNNLYGLSLVVYTVMLDLVLIALSYGFILYTVAGLASQEEQIRAFQTCTSHLCAVLVFFVPMTGLSLVHRFGKNAPPAVHLLMANIYLFVPPMLNPVIYSIKTKEIRRAISKLLGFGKDNSESWGEMHH", "length": 323, "header": "tr|A0A9J7FRK9-1|A0A9J7FRK9_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100773549 PE=3 SV=1 CANONICAL=A0A9J7FRK9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK9/entry#A0A9J7FRK9-1", "sequence": { "sequence": "MVLSNITHFSPMFYLSSFPGLEAFKHWIFIPFFLMYLVAISGNCLILMIIKTSPRLHTPMYYLLSLLALTDLGLSMSTLPTTVGIFWFNYHSIYFGACQIQMFCIHSFSFMESAVLLVMSFDRYVAICHPLRYSVIITGERVIRIGLCVILRGPVALIPIVLLLKAFPYCGPLVLSHSFCLHQEVIHLACVDTTFNNLYGLSLVVYTVMLDLVLIALSYGFILYTVAGLASQEEQIRAFQTCTSHLCAVLVFFVPMTGLSLVHRFGKNAPPAVHLLMANIYLFVPPMLNPVIYSIKTKEIRRAISKLLGFGKDNSESWGEMHH", "length": 323, "header": "tr|A0A9J7FRK9-1|A0A9J7FRK9_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100773549 PE=3 SV=1 CANONICAL=A0A9J7FRK9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRK9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267094" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Herc1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62", "locus": {} } ], "crossref": [ { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12881", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12881", "database": "CDD", 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"https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772726", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772726", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FU62", "url": "https://www.orthodb.org/?gene=A0A9J7FU62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22872:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22872:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FRR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUZ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW57-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATMVPPVKLKWLEHLNSSWITEDSESIATREGVTVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMPVSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADTLGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVHTMEKNKLLSSQEGMISFDCFMAILMQMRRSLGSSADRSQWREPTRTSEGLCSLYEAALCLFEEVCRMASDYSRTCASPDSIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHNFLKLCLKLLSNHLALALAGGVATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVASLLGYSSPSDAADLSTVCMGYGNLSDQPYGPQTCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKYLFGTSPSENSQPAHLHELLCSLQKQLLAFCHINNITENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARPLLSYLLDLLPPLDCLNRLLPAAALLEDQELQWPLHGGPEVIDPAGVPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTAYWMKTPLFSDGVEMDTPQLDKCMSCLLDVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLLDTVSRFVLAALLKHTNLLSQACGESRYQPGKSLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWISDNQDSADIDPQEHSFTRTIDEEAEMEEQAERDREDGHPEPDDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMSSGAGSGVRADDPPPQSQQERRVSTDLPEGQDVYTAACNSVIHRCALLILGVSPVIDELQKRREEGQLQQPSVSASEGSGLMTRSESLTAESRLVHASPSYRLIKSRSESDLSQPESDEEGYALSGRRNVDLDLASSHRKRGPMHSQLESLSDSWTRLKHTRDWFYNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKEPEESMSTSPQASIIAMEQQQLRAELRLEALHQILTLLSGMEEKGSILLTGSRSSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTGTKGESGRLHHYQDGIRAAKRNIQIEIQVAVHKIYQQLSATLERALQANKHHIEAQQRLLLVTVFALSVHYQPVDVSLAISTGLLNVLSQLCGTDTMLGQPLQLLPKTGVSQLSTALKVASTRLLQILAITTGTYADKLSPKVVQSLLDLLCSQLKNLLSQTGVLFMASFGEGEEVEEEEKKVDSSGETEKKDFRAALRKQHAAELHLGDFLVFLRRVVSSKAIQSKMASPKWTEVLLNIASQKCSSGIPLVGNLRTRLLALHVLEAVLPACESGVEDDQMAQVVERLFSLLSDCMWETPIAQAKHAIQIKEKEQEIKLQKQGELEEEDENLPIQEVSFDPEKAQCCIVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPICSPVAAVLAEATIQLIRILHRTDRWTYCINKKMMERLHKIKICIKESGQKLKKSRSVQSREENEVREEKENKEEEKGKHNRHGLADLSEPQLRTLCIEVWPVLAVIGGVDAGLRVGGRCVHKQTGRHATLLGVVKEGSTSAKVQWDEAEITISFPTFWSPSDTPLYNLEPCEPLLFDVARFRGLTASVLLDLTYLTGIHEDVGKQSVKRHEKKHRHESEEKVDSEQKPESESMLDVRTGLMSDDAKSQGATSSKSENEIASFSLEPTLPGVESQHQVTEGKRKNHEHTSKTHDIAQSEIRAVQLSYLYLGAMKSLSALLGCSKYAELLLIPKVLAENGHNSDCASSPVVHEDVEMRAALQFLMRHMVKRAVMRSPIKRALGLADLERAQAMIYKLVVHGLLEDQFGGKIKQEIDQPAEESDHAQQAQTPVTTSPSASSTTSFMSSSLEDTTTATTPVTDTETVPASESPGVMPLSLLRQMFSSYPTTTVLPTRRAQTPPISSLPTSPSDEVGRRQSLTSPDSQSTRPANRTALSDPSSRLSTSPPPPAIAVPLLEMGFSLRQIAKAMEATGARGEADAQNITVLAMWMIEHPGHEDEEEPQPSSTADSRHGTTVLGSGGKSNDPCYLQSPGDIPSADAAEMEEGFSESPDNLDHTENAASGSGPPARGRSTVTRRHKFDLAARTLLARAAGLYRSVQAHRNQSRREGISLQQDPGALYDFNLDEELEIDLDDEAMEAMFGQDLTSDNDILGMWIPEVLDWPTWHVCESEDREEVVVCELCECNVVSFNQHMKRNHPGCGRSANRQGYRSNGSYVDGWFGGECGSGNPYYLLCGSCREKYLALKTKTKTTNSERYKGQAPDLIGKQDSVYEEDWDMLDIDEDEKLTGEEEFELLAGPLGLNDRRIVPEPVQFPDSDPLGASVAMVTATNSMEETLMQIGCHGSVEKSSSGRVTLGEQAAALANPHDRVVALRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRLMCLAAAGRAGLSTSPSAMASTSERSRGGHSKASKPISCLAYLSTAVGCLASNTPSAAKLLVQLCTQNLISAATGVNLTTVDDPIQRKFLPSFLRGIAEENKLVTSPNFVVTQALVALLADKGAKLRPNYDKSEVEKKGFIAQLYAHPSYDPSAVGPLELANALAACCLSSRLSSQHRQWAAQQLVRTLAAHDRDNQTAPQTLADMGGDLRKCSFIKLEAHQNRVMTCVWCNKKGLLATSGNDGTIRVWNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEKMVNIWQVNGGKGLVDIQPHWVSALAWPEEGPATAWSGESPELLLVGRMDGSLGLIEVVDVSTMHRRELEHCYRKDVSVTCIAWFSEDRPFAVGYFDGKLLMGTKEPLEKGGIVLIDAHKETLVSMKWDPTGHILMTCAKEENVKLWGPVSGCWRCLHSLCHPSTVNGIAWCSLPGKGSKLQLLMATGCQNGLVCVWRIPQDTTQTSMTCSEGWWDQESNCQDGCRKSAGAKCVYQLRGHITPVRTVAFSSDGLALVSGGLGGLMNIWSLRDGSVLQTVVIGSGAIQTTVWIPEVGVAACSNRSKDVLVVNCTAEWASANHVLATCRTALKQQGILGLNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCSPPVPPHHQSCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDLEPVPEDELVLLMDNSKWINGMDEQIMSWATSRPEDWHLGGKCDVYLWGAGRHGQLAEAGRNVMVPATAPSFSQAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGAVREVSIHTVRARLRLLYHFSDLMYSSWRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRISTRGRKCKPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEICVEVLKKVVRYREVDEQHQLVQWLWRTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNYMLSRNVDNAEGSDTDY", "length": 4876, "header": "tr|A0A9J7FU62-1|A0A9J7FU62_CRIGR Isoform 1 of HECT-type E3 ubiquitin transferase OS=Cricetulus griseus OX=10029 GN=Herc1 PE=4 SV=1 CANONICAL=A0A9J7FU62-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62/entry#A0A9J7FRR2-1", "sequence": { "sequence": "MATMVPPVKLKWLEHLNSSWITEDSESIATREGVTVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMPVSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADTLGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVHTMEKNKLLSSQEGMISFDCFMAILMQMRRSLGSSADRSQWREPTRTSEGLCSLYEAALCLFEEVCRMASDYSRTCASPDSIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHNFLKLCLKLLSNHLALALAGGVATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVASLLGYSSPSDAADLSTVCMGYGNLSDQPYGPQTCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKYLFGTSPSENSQPAHLHELLCSLQKQLLAFCHINNITENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARPLLSYLLDLLPPLDCLNRLLPAAALLEDQELQWPLHGGPEVIDPAGVPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTAYWMKTPLFSDGVEMDTPQLDKCMSCLLDVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLLDTVSRFVLAALLKHTNLLSQACGESRYQPGKSLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWISDNQDSADIDPQEHSFTRTIDEEAEMEEQAERDREDGHPEPDDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMSSGAGSGVRADDPPPQSQQERRVSTDLPEGQDVYTAACNSVIHRCALLILGVSPVIDELQKRREEGQLQQPSVSASEGSGLMTRSESLTAESRLVHASPSYRLIKSRSESDLSQPESDEEGYALSGRRNVDLDLASSHRKRGPMHSQLESLSDSWTRLKHTRDWFYNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKEPEESMSTSPQASIIAMEQQQLRAELRLEALHQILTLLSGMEEKGSILLTGSRSSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTGTKGESGRLHHYQDGIRAAKRNIQIEIQVAVHKIYQQLSATLERALQANKHHIEAQQRLLLVTVFALSVHYQPVDVSLAISTGLLNVLSQLCGTDTMLGQPLQLLPKTGVSQLSTALKVASTRLLQILAITTGTYADKLSPKVVQSLLDLLCSQLKNLLSQTGVLFMASFGEGEEVEEEEKKVDSSGETEKKDFRAALRKQHAAELHLGDFLVFLRRVVSSKAIQSKMASPKWTEVLLNIASQKCSSGIPLVGNLRTRLLALHVLEAVLPACESGVEDDQMAQVVERLFSLLSDCMWETPIAQAKHAIQIKEKEQEIKLQQGELEEEDENLPIQEVSFDPEKAQCCIVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPICSPVAAVLAEATIQLIRILHRTDRWTYCINKKMMERLHKIKICIKESGQKLKKSRSVQSREENEVREEKENKEEEKGKHNRHGLADLSEPQLRTLCIEVWPVLAVIGGVDAGLRVGGRCVHKQTGRHATLLGVVKEGSTSAKVQWDEAEITISFPTFWSPSDTPLYNLEPCEPLLFDVARFRGLTASVLLDLTYLTGIHEDVGKQSVKRHEKKHRHESEEKVDSEQKPESESMLDVRTGLMSDDAKSQGATSSKSENEIASFSLEPTLPGVESQHQVTEGKRKNHEHTSKTHDIAQSEIRAVQLSYLYLGAMKSLSALLGCSKYAELLLIPKVLAENGHNSDCASSPVVHEDVEMRAALQFLMRHMVKRAVMRSPIKRALGLADLERAQAMIYKLVVHGLLEDQFGGKIKQEIDQPAEESDHAQQAQTPVTTSPSASSTTSFMSSSLEDTTTATTPVTDTETVPASESPGVMPLSLLRQMFSSYPTTTVLPTRRAQTPPISSLPTSPSDEVGRRQSLTSPDSQSTRPANRTALSDPSSRLSTSPPPPAIAVPLLEMGFSLRQIAKAMEATGARGEADAQNITVLAMWMIEHPGHEDEEEPQPSSTADSRHGTTVLGSGGKSNDPCYLQSPGDIPSADAAEMEEGFSESPDNLDHTENAASGSGPPARGRSTVTRRHKFDLAARTLLARAAGLYRSVQAHRNQSRREGISLQQDPGALYDFNLDEELEIDLDDEAMEAMFGQDLTSDNDILGMWIPEVLDWPTWHVCESEDREEVVVCELCECNVVSFNQHMKRNHPGCGRSANRQGYRSNGSYVDGWFGGECGSGNPYYLLCGSCREKYLALKTKTKTTNSERYKGQAPDLIGKQDSVYEEDWDMLDIDEDEKLTGEEEFELLAGPLGLNDRRIVPEPVQFPDSDPLGASVAMVTATNSMEETLMQIGCHGSVEKSSSGRVTLGEQAAALANPHDRVVALRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRLMCLAAAGRAGLSTSPSAMASTSERSRGGHSKASKPISCLAYLSTAVGCLASNTPSAAKLLVQLCTQNLISAATGVNLTTVDDPIQRKFLPSFLRGIAEENKLVTSPNFVVTQALVALLADKGAKLRPNYDKSEVEKKGFIAQLYAHPSYDPSAVGPLELANALAACCLSSRLSSQHRQWAAQQLVRTLAAHDRDNQTAPQTLADMGGDLRKCSFIKLEAHQNRVMTCVWCNKKGLLATSGNDGTIRVWNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEKMVNIWQVNGGKGLVDIQPHWVSALAWPEEGPATAWSGESPELLLVGRMDGSLGLIEVVDVSTMHRRELEHCYRKDVSVTCIAWFSEDRPFAVGYFDGKLLMGTKEPLEKGGIVLIDAHKETLVSMKWDPTGHILMTCAKEENVKLWGPVSGCWRCLHSLCHPSTVNGIAWCSLPGKGSKLQLLMATGCQNGLVCVWRIPQDTTQTSMTCSEGWWDQESNCQDGCRKSAGAKCVYQLRGHITPVRTVAFSSDGLALVSGGLGGLMNIWSLRDGSVLQTVVIGSGAIQTTVWIPEVGVAACSNRSKDVLVVNCTAEWASANHVLATCRTALKQQGILGLNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCSPPVPPHHQSCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDLEPVPEDELVLLMDNSKWINGMDEQIMSWATSRPEDWHLGGKCDVYLWGAGRHGQLAEAGRNVMVPATAPSFSQAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGAVREVSIHTVRARLRLLYHFSDLMYSSWRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRISTRGRKCKPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEICVEVLKKVVRYREVDEQHQLVQWLWRTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNYMLSRNVDNAEGSDTDY", "length": 4875, "header": "tr|A0A9J7FRR2-1|A0A9J7FU62_CRIGR Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Cricetulus griseus OX=10029 GN=Herc1 PE=4 SV=1 CANONICAL=A0A9J7FU62-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FU62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62/entry#A0A9J7FU62-1", "sequence": { "sequence": "MATMVPPVKLKWLEHLNSSWITEDSESIATREGVTVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMPVSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADTLGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVHTMEKNKLLSSQEGMISFDCFMAILMQMRRSLGSSADRSQWREPTRTSEGLCSLYEAALCLFEEVCRMASDYSRTCASPDSIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHNFLKLCLKLLSNHLALALAGGVATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVASLLGYSSPSDAADLSTVCMGYGNLSDQPYGPQTCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKYLFGTSPSENSQPAHLHELLCSLQKQLLAFCHINNITENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARPLLSYLLDLLPPLDCLNRLLPAAALLEDQELQWPLHGGPEVIDPAGVPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTAYWMKTPLFSDGVEMDTPQLDKCMSCLLDVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLLDTVSRFVLAALLKHTNLLSQACGESRYQPGKSLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWISDNQDSADIDPQEHSFTRTIDEEAEMEEQAERDREDGHPEPDDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMSSGAGSGVRADDPPPQSQQERRVSTDLPEGQDVYTAACNSVIHRCALLILGVSPVIDELQKRREEGQLQQPSVSASEGSGLMTRSESLTAESRLVHASPSYRLIKSRSESDLSQPESDEEGYALSGRRNVDLDLASSHRKRGPMHSQLESLSDSWTRLKHTRDWFYNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKEPEESMSTSPQASIIAMEQQQLRAELRLEALHQILTLLSGMEEKGSILLTGSRSSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTGTKGESGRLHHYQDGIRAAKRNIQIEIQVAVHKIYQQLSATLERALQANKHHIEAQQRLLLVTVFALSVHYQPVDVSLAISTGLLNVLSQLCGTDTMLGQPLQLLPKTGVSQLSTALKVASTRLLQILAITTGTYADKLSPKVVQSLLDLLCSQLKNLLSQTGVLFMASFGEGEEVEEEEKKVDSSGETEKKDFRAALRKQHAAELHLGDFLVFLRRVVSSKAIQSKMASPKWTEVLLNIASQKCSSGIPLVGNLRTRLLALHVLEAVLPACESGVEDDQMAQVVERLFSLLSDCMWETPIAQAKHAIQIKEKEQEIKLQKQGELEEEDENLPIQEVSFDPEKAQCCIVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPICSPVAAVLAEATIQLIRILHRTDRWTYCINKKMMERLHKIKICIKESGQKLKKSRSVQSREENEVREEKENKEEEKGKHNRHGLADLSEPQLRTLCIEVWPVLAVIGGVDAGLRVGGRCVHKQTGRHATLLGVVKEGSTSAKVQWDEAEITISFPTFWSPSDTPLYNLEPCEPLLFDVARFRGLTASVLLDLTYLTGIHEDVGKQSVKRHEKKHRHESEEKVDSEQKPESESMLDVRTGLMSDDAKSQGATSSKSENEIASFSLEPTLPGVESQHQVTEGKRKNHEHTSKTHDIAQSEIRAVQLSYLYLGAMKSLSALLGCSKYAELLLIPKVLAENGHNSDCASSPVVHEDVEMRAALQFLMRHMVKRAVMRSPIKRALGLADLERAQAMIYKLVVHGLLEDQFGGKIKQEIDQPAEESDHAQQAQTPVTTSPSASSTTSFMSSSLEDTTTATTPVTDTETVPASESPGVMPLSLLRQMFSSYPTTTVLPTRRAQTPPISSLPTSPSDEVGRRQSLTSPDSQSTRPANRTALSDPSSRLSTSPPPPAIAVPLLEMGFSLRQIAKAMEATGARGEADAQNITVLAMWMIEHPGHEDEEEPQPSSTADSRHGTTVLGSGGKSNDPCYLQSPGDIPSADAAEMEEGFSESPDNLDHTENAASGSGPPARGRSTVTRRHKFDLAARTLLARAAGLYRSVQAHRNQSRREGISLQQDPGALYDFNLDEELEIDLDDEAMEAMFGQDLTSDNDILGMWIPEVLDWPTWHVCESEDREEVVVCELCECNVVSFNQHMKRNHPGCGRSANRQGYRSNGSYVDGWFGGECGSGNPYYLLCGSCREKYLALKTKTKTTNSERYKGQAPDLIGKQDSVYEEDWDMLDIDEDEKLTGEEEFELLAGPLGLNDRRIVPEPVQFPDSDPLGASVAMVTATNSMEETLMQIGCHGSVEKSSSGRVTLGEQAAALANPHDRVVALRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRLMCLAAAGRAGLSTSPSAMASTSERSRGGHSKASKPISCLAYLSTAVGCLASNTPSAAKLLVQLCTQNLISAATGVNLTTVDDPIQRKFLPSFLRGIAEENKLVTSPNFVVTQALVALLADKGAKLRPNYDKSEVEKKGFIAQLYAHPSYDPSAVGPLELANALAACCLSSRLSSQHRQWAAQQLVRTLAAHDRDNQTAPQTLADMGGDLRKCSFIKLEAHQNRVMTCVWCNKKGLLATSGNDGTIRVWNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEKMVNIWQVNGGKGLVDIQPHWVSALAWPEEGPATAWSGESPELLLVGRMDGSLGLIEVVDVSTMHRRELEHCYRKDVSVTCIAWFSEDRPFAVGYFDGKLLMGTKEPLEKGGIVLIDAHKETLVSMKWDPTGHILMTCAKEENVKLWGPVSGCWRCLHSLCHPSTVNGIAWCSLPGKGSKLQLLMATGCQNGLVCVWRIPQDTTQTSMTCSEGWWDQESNCQDGCRKSAGAKCVYQLRGHITPVRTVAFSSDGLALVSGGLGGLMNIWSLRDGSVLQTVVIGSGAIQTTVWIPEVGVAACSNRSKDVLVVNCTAEWASANHVLATCRTALKQQGILGLNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCSPPVPPHHQSCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDLEPVPEDELVLLMDNSKWINGMDEQIMSWATSRPEDWHLGGKCDVYLWGAGRHGQLAEAGRNVMVPATAPSFSQAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGAVREVSIHTVRARLRLLYHFSDLMYSSWRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRISTRGRKCKPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEICVEVLKKVVRYREVDEQHQLVQWLWRTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNYMLSRNVDNAEGSDTDY", "length": 4876, "header": "tr|A0A9J7FU62-1|A0A9J7FU62_CRIGR Isoform 1 of HECT-type E3 ubiquitin transferase OS=Cricetulus griseus OX=10029 GN=Herc1 PE=4 SV=1 CANONICAL=A0A9J7FU62-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FUS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62/entry#A0A9J7FUS1-1", "sequence": { "sequence": "MATMVPPVKLKWLEHLNSSWITEDSESIATREGVTVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMPVSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADTLGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVHTMEKNKLLSSQEGMISFDCFMAILMQMRRSLGSSADRSQWREPTRTSEGLCSLYEAALCLFEEVCRMASDYSRTCASPDSIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHNFLKLCLKLLSNHLALALAGGVATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVASLLGYSSPSDAADLSTVCMGYGNLSDQPYGPQTCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKYLFGTSPSENSQPAHLHELLCSLQKQLLAFCHINNITENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARPLLSYLLDLLPPLDCLNRLLPAAALLEDQELQWPLHGGPEVIDPAGVPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTAYWMKTPLFSDGVEMDTPQLDKCMSCLLDVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLLDTVSRFVLAALLKHTNLLSQACGESRYQPGKSLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWISDNQDSADIDPQEHSFTRTIDEEAEMEEQAERDREDGHPEPDDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMSSGAGSGVRADDPPPQSQQERRVSTDLPEGQDVYTAACNSVIHRCALLILGVSPVIDELQKRREEGQLQQPSVSASEGSGLMTRSESLTAESRLVHASPSYRLIKSRSESDLSQPESDEEGYALSGRRNVDLDLASSHRKRGPMHSQLESLSDSWTRLKHTRDWFYNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKEPEESMSTSPQASIIAMEQQQLRAELRLEALHQILTLLSGMEEKGSILLTGSRSSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTGTKGESGRLHHYQDGIRAAKRNIQIEIQVAVHKIYQQLSATLERALQANKHHIEAQQRLLLVTVFALSVHYQPVDVSLAISTGLLNVLSQLCGTDTMLGQPLQLLPKTGVSQLSTALKVASTRLLQILAITTGTYADKLSPKVVQSLLDLLCSQLKNLLSQTGVLFMASFGEGEEVEEEEKKVDSSGETEKKDFRAALRKQHAAELHLGDFLVFLRRVVSSKAIQSKMASPKWTEVLLNIASQKCSSGIPLVGNLRTRLLALHVLEAVLPACESGVEDDQMAQVVERLFSLLSDCMWETPIAQAKHAIQIKEKEQEIKLQKQGELEEEDENLPIQEVSFDPEKAQCCIVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPICSPVAAVLAEATIQLIRILHRTDRWTYCINKKMMERLHKIKICIKESGQKLKKSRSVQSREENEVREEKENKEEEKGKHNRHGLADLSEPQLRTLCIEVWPVLAVIGGVDAGLRVGGRCVHKQTGRHATLLGVVKEGSTSAKVQWDEAEITISDTPLYNLEPCEPLLFDVARFRGLTASVLLDLTYLTGIHEDVGKQSVKRHEKKHRHESEEKVDSEQKPESESMLDVRTGLMSDDAKSQGATSSKSENEIASFSLEPTLPGVESQHQVTEGKRKNHEHTSKTHDIAQSEIRAVQLSYLYLGAMKSLSALLGCSKYAELLLIPKVLAENGHNSDCASSPVVHEDVEMRAALQFLMRHMVKRAVMRSPIKRALGLADLERAQAMIYKLVVHGLLEDQFGGKIKQEIDQPAEESDHAQQAQTPVTTSPSASSTTSFMSSSLEDTTTATTPVTDTETVPASESPGVMPLSLLRQMFSSYPTTTVLPTRRAQTPPISSLPTSPSDEVGRRQSLTSPDSQSTRPANRTALSDPSSRLSTSPPPPAIAVPLLEMGFSLRQIAKAMEATGARGEADAQNITVLAMWMIEHPGHEDEEEPQPSSTADSRHGTTVLGSGGKSNDPCYLQSPGDIPSADAAEMEEGFSESPDNLDHTENAASGSGPPARGRSTVTRRHKFDLAARTLLARAAGLYRSVQAHRNQSRREGISLQQDPGALYDFNLDEELEIDLDDEAMEAMFGQDLTSDNDILGMWIPEVLDWPTWHVCESEDREEVVVCELCECNVVSFNQHMKRNHPGCGRSANRQGYRSNGSYVDGWFGGECGSGNPYYLLCGSCREKYLALKTKTKTTNSERYKGQAPDLIGKQDSVYEEDWDMLDIDEDEKLTGEEEFELLAGPLGLNDRRIVPEPVQFPDSDPLGASVAMVTATNSMEETLMQIGCHGSVEKSSSGRVTLGEQAAALANPHDRVVALRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRLMCLAAAGRAGLSTSPSAMASTSERSRGGHSKASKPISCLAYLSTAVGCLASNTPSAAKLLVQLCTQNLISAATGVNLTTVDDPIQRKFLPSFLRGIAEENKLVTSPNFVVTQALVALLADKGAKLRPNYDKSEVEKKGFIAQLYAHPSYDPSAVGPLELANALAACCLSSRLSSQHRQWAAQQLVRTLAAHDRDNQTAPQTLADMGGDLRKCSFIKLEAHQNRVMTCVWCNKKGLLATSGNDGTIRVWNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEKMVNIWQVNGGKGLVDIQPHWVSALAWPEEGPATAWSGESPELLLVGRMDGSLGLIEVVDVSTMHRRELEHCYRKDVSVTCIAWFSEDRPFAVGYFDGKLLMGTKEPLEKGGIVLIDAHKETLVSMKWDPTGHILMTCAKEENVKLWGPVSGCWRCLHSLCHPSTVNGIAWCSLPGKGSKLQLLMATGCQNGLVCVWRIPQDTTQTSMTCSEGWWDQESNCQDGCRKSAGAKCVYQLRGHITPVRTVAFSSDGLALVSGGLGGLMNIWSLRDGSVLQTVVIGSGAIQTTVWIPEVGVAACSNRSKDVLVVNCTAEWASANHVLATCRTALKQQGILGLNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCSPPVPPHHQSCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDLEPVPEDELVLLMDNSKWINGMDEQIMSWATSRPEDWHLGGKCDVYLWGAGRHGQLAEAGRNVMVPATAPSFSQAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGAVREVSIHTVRARLRLLYHFSDLMYSSWRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRISTRGRKCKPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEICVEVLKKVVRYREVDEQHQLVQWLWRTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNYMLSRNVDNAEGSDTDY", "length": 4868, "header": "tr|A0A9J7FUS1-1|A0A9J7FUS1_CRIGR Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Cricetulus griseus OX=10029 GN=Herc1 PE=4 SV=1 CANONICAL=A0A9J7FU62-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FUZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62/entry#A0A9J7FUZ1-1", "sequence": { "sequence": "MATMVPPVKLKWLEHLNSSWITEDSESIATREGVTVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMPVSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADTLGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVHTMEKNKLLSSQEGMISFDCFMAILMQMRRSLGSSADRSQWREPTRTSEGLCSLYEAALCLFEEVCRMASDYSRTCASPDSIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHNFLKLCLKLLSNHLALALAGGVATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVASLLGYSSPSDAADLSTVCMGYGNLSDQPYGPQTCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKYLFGTSPSENSQPAHLHELLCSLQKQLLAFCHINNITENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARPLLSYLLDLLPPLDCLNRLLPAAALLEDQELQWPLHGGPEVIDPAGVPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTAYWMKTPLFSDGVEMDTPQLDKCMSCLLDVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLLDTVSRFVLAALLKHTNLLSQACGESRYQPGKSLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWISDNQDSADIDPQEHSFTRTIDEEAEMEEQAERDREDGHPEPDDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMSSGAGSGVRADDPPPQSQQERRVSTDLPEGQDVYTAACNSVIHRCALLILGVSPVIDELQKRREEGQLQQPSVSASEGSGLMTRSESLTAESRLVHASPSYRLIKSRSESDLSQPESDEEGYALSGRRNVDLDLASSHRKRGPMHSQLESLSDSWTRLKHTRDWFYNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKEPEESMSTSPQASIIAMEQQQLRAELRLEALHQILTLLSGMEEKGSILLTGSRSSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTGTKGESGRLHHYQDGIRAAKRNIQIEIQVAVHKIYQQLSATLERALQANKHHIEAQQRLLLVTVFALSVHYQPVDVSLAISTGLLNVLSQLCGTDTMLGQPLQLLPKTGVSQLSTALKVASTRLLQILAITTGTYADKLSPKVVQSLLDLLCSQLKNLLSQTGVLFMASFGEGEEVEEEEKKVDSSGETEKKDFRAALRKQHAAELHLGDFLVFLRRVVSSKAIQSKMASPKWTEVLLNIASQKCSSGIPLVGNLRTRLLALHVLEAVLPACESGVEDDQMAQVVERLFSLLSDCMWETPIAQAKHAIQIKEKEQEIKLQKQGELEEEDENLPIQEVSFDPEKAQCCIVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPICSPVAAVLAEATIQLIRILHRTDRWTYCINKKMMERLHKIKICIKESGQKLKKSRSVQSREENEVREEKENKEEEKGKHNRHGLADLSEPQLRTLCIEVWPVLAVIGGVDAGLRVGGRCVHKQTGRHATLLGVVKEGSTSAKVQWDEAEITISFPTFWSPSDTPLYNLEPCEPLLFDVARFRGLTASVLLDLTYLTGIHEDVGKQSVKRHEKKHRHESEEKVDSEQKPESESMLDVRTGLMSDDAKSQGATSSKSENEIASFSLEPTLPGVESQHQVTEGKRKNHEHTSKTHDIAQSEIRAVQLSYLYLGAMKSLSALLGCSKYAELLLIPKVLAENGHNSDCASSPVVHEDVEMRAALQFLMRHMVKRAVMRSPIKRALGLADLERAQAMIYKLVVHGLLEDQFGGKIKQEIDQPAEESDHAQQAQTPVTTSPSASSTTSFMSSSLEDTTTATTPVTDTETVPASESPGVMPLSLLRQMFSSYPTTTVLPTRRAQTPPISSLPTSPSDEVGRRQSLTSPDSQSTRPANRTALSDPSSRLSTSPPPPAIAVPLLEMGFSLRQIAKAMEATGARGEADAQNITVLAMWMIEHPGHEDEEEPQPSSTADSRHGTTVLGSGGKSNDPCYLQSPGDIPSADAAEMEEGFSESPDNLDHTENAASGSGPPARGRSTVTRRHKFDLAARTLLARAAGLYRSVQAHRNQSRREGISLQQDPGALYDFNLDEELEIDLDDEAMEAMFGQDLTSDNDILGMWIPEVLDWPTWHVCESEDREEVVVCELCECNVVSFNQHMKRNHPGCGRSANRQGYRSNGSYVDGWFGGECGSGNPYYLLCGSCREKYLALKTKTKTTNSERYKGQAPDLIGKQDSVYEEDWDMLDIDEDEKLTGEEEFELLAGPLGLNDRRIVPEPVQFPDSDPLGASVAMVTATNSMEETLMQIGCHGSVEKSSSGRVTLGEQAAALANPHDRVVALRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRLMCLAAAGRAGLSTSPSAMASTSERSRGGHSKASKPISCLAYLSTAVGCLASNTPSAAKLLVQLCTQNLISAATGVNLTTVDDPIQRKFLPSFLRGIAEENKLVTSPNFVVTQALVALLADKGAKLRPNYDKSEVEKKGPLELANALAACCLSSRLSSQHRQWAAQQLVRTLAAHDRDNQTAPQTLADMGGDLRKCSFIKLEAHQNRVMTCVWCNKKGLLATSGNDGTIRVWNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEKMVNIWQVNGGKGLVDIQPHWVSALAWPEEGPATAWSGESPELLLVGRMDGSLGLIEVVDVSTMHRRELEHCYRKDVSVTCIAWFSEDRPFAVGYFDGKLLMGTKEPLEKGGIVLIDAHKETLVSMKWDPTGHILMTCAKEENVKLWGPVSGCWRCLHSLCHPSTVNGIAWCSLPGKGSKLQLLMATGCQNGLVCVWRIPQDTTQTSMTCSEGWWDQESNCQDGCRKSAGAKCVYQLRGHITPVRTVAFSSDGLALVSGGLGGLMNIWSLRDGSVLQTVVIGSGAIQTTVWIPEVGVAACSNRSKDVLVVNCTAEWASANHVLATCRTALKQQGILGLNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCSPPVPPHHQSCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDLEPVPEDELVLLMDNSKWINGMDEQIMSWATSRPEDWHLGGKCDVYLWGAGRHGQLAEAGRNVMVPATAPSFSQAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGAVREVSIHTVRARLRLLYHFSDLMYSSWRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRISTRGRKCKPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEICVEVLKKVVRYREVDEQHQLVQWLWRTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNYMLSRNVDNAEGSDTDY", "length": 4859, "header": "tr|A0A9J7FUZ1-1|A0A9J7FUZ1_CRIGR Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Cricetulus griseus OX=10029 GN=Herc1 PE=4 SV=1 CANONICAL=A0A9J7FU62-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FW57-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62/entry#A0A9J7FW57-1", "sequence": { "sequence": "MATMVPPVKLKWLEHLNSSWITEDSESIATREGVTVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMPVSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADTLGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVHTMEKNKLLSSQEGMISFDCFMAILMQMRRSLGSSADRSQWREPTRTSEGLCSLYEAALCLFEEVCRMASDYSRTCASPDSIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHNFLKLCLKLLSNHLALALAGGVATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVASLLGYSSPSDAADLSTVCMGYGNLSDQPYGPQTCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKYLFGTSPSENSQPAHLHELLCSLQKQLLAFCHINNITENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARPLLSYLLDLLPPLDCLNRLLPAAALLEDQELQWPLHGGPEVIDPAGVPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTAYWMKTPLFSDGVEMDTPQLDKCMSCLLDVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLLDTVSRFVLAALLKHTNLLSQACGESRYQPGKSLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWISDNQDSADIDPQEHSFTRTIDEEAEMEEQAERDREDGHPEPDDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMSSGAGSGVRADDPPPQSQQERRVSTDLPEGQDVYTAACNSVIHRCALLILGVSPVIDELQKRREEGQLQQPSVSASEGSGLMTRSESLTAESRLVHASPSYRLIKSRSESDLSQPESDEEGYALSGRRNVDLDLASSHRKRGPMHSQLESLSDSWTRLKHTRDWFYNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKEPEESMSTSPQASIIAMEQQQLRAELRLEALHQILTLLSGMEEKGSILLTGSRSSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTGTKGESGRLHHYQDGIRAAKRNIQIEIQVAVHKIYQQLSATLERALQANKHHIEAQQRLLLVTVFALSVHYQPVDVSLAISTGLLNVLSQLCGTDTMLGQPLQLLPKTGVSQLSTALKVASTRLLQILAITTGTYADKLSPKVVQSLLDLLCSQLKNLLSQTGVLFMASFGEGEEVEEEEKKVDSSGETEKKDFRAALRKQHAAELHLGDFLVFLRRVVSSKAIQSKMASPKWTEVLLNIASQKCSSGIPLVGNLRTRLLALHVLEAVLPACESGVEDDQMAQVVERLFSLLSDCMWETPIAQAKHAIQIKEKEQEIKLQKQGELEEEDENLPIQEVSFDPEKAQCCIVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPICSPVAAVLAEATIQLIRILHRTDRWTYCINKKMMERLHKIKICIKESGQKLKKSRSVQSREENEVREEKENKEEEKGKHNRHGLADLSEPQLRTLCIEVWPVLAVIGGVDAGLRVGGRCVHKQTGRHATLLGVVKEGSTSAKVQWDEAEITISFPTFWSPSDTPLYNLEPCEPLLFDVARFRGLTASVLLDLTYLTGIHEDVGKQSVKRHEKKHRHESEEKVDSEQKPESESMLDVRTGLMSDDAKSQGATSSKSENEIASFSLEPTLPGVESQHQVTEGKRKNHEHTSKTHDIAQSEIRAVQLSYLYLGAMKSLSALLGCSKYAELLLIPKVLAENGHNSDCASSPVVHEDVEMRAALQFLMRHMVKRAVMRSPIKRALGLADLERAQAMIYKLVVHGLLEDQFGGKIKQEIDQPAEESDHAQQAQTPVTTSPSASSTTSFMSSSLEDTTTATTPVTDTETVPASESPGVMPLSLLRQMFSSYPTTTVLPTRRAQTPPISSLPTSPSDEVGRRQSLTSPDSQSTRPANRTALSDPSSRLSTSPPPPAIAVPLLEMGFSLRQIAKAMEATGARGEADAQNITVLAMWMIEHPGHEDEEEPQPSSTADSRHGTTVLGSGGKSNDPCYLQSPGDIPSADAAEMEEGFSESPDNLDHTENAASGSGPPARGRSTVTRRHKFDLAARTLLARAAGLYRSVQAHRNQSRREGISLQQDPGALYDFNLDEELEIDLDDEAMEAMFGQDLTSDNDILGMWIPEVLDWPTWHVCESEDREEVVVCELCECNVVSFNQHMKRNHPGCGRSANRQGYRSNGSYVDGWFGGECGSGNPYYLLCGSCREKYLALKTKTKTTNSERYKGQAPDLIGKQDSVYEDWDMLDIDEDEKLTGEEEFELLAGPLGLNDRRIVPEPVQFPDSDPLGASVAMVTATNSMEETLMQIGCHGSVEKSSSGRVTLGEQAAALANPHDRVVALRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRLMCLAAAGRAGLSTSPSAMASTSERSRGGHSKASKPISCLAYLSTAVGCLASNTPSAAKLLVQLCTQNLISAATGVNLTTVDDPIQRKFLPSFLRGIAEENKLVTSPNFVVTQALVALLADKGAKLRPNYDKSEVEKKGFIAQLYAHPSYDPSAVGPLELANALAACCLSSRLSSQHRQWAAQQLVRTLAAHDRDNQTAPQTLADMGGDLRKCSFIKLEAHQNRVMTCVWCNKKGLLATSGNDGTIRVWNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEKMVNIWQVNGGKGLVDIQPHWVSALAWPEEGPATAWSGESPELLLVGRMDGSLGLIEVVDVSTMHRRELEHCYRKDVSVTCIAWFSEDRPFAVGYFDGKLLMGTKEPLEKGGIVLIDAHKETLVSMKWDPTGHILMTCAKEENVKLWGPVSGCWRCLHSLCHPSTVNGIAWCSLPGKGSKLQLLMATGCQNGLVCVWRIPQDTTQTSMTCSEGWWDQESNCQDGCRKSAGAKCVYQLRGHITPVRTVAFSSDGLALVSGGLGGLMNIWSLRDGSVLQTVVIGSGAIQTTVWIPEVGVAACSNRSKDVLVVNCTAEWASANHVLATCRTALKQQGILGLNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCSPPVPPHHQSCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDLEPVPEDELVLLMDNSKWINGMDEQIMSWATSRPEDWHLGGKCDVYLWGAGRHGQLAEAGRNVMVPATAPSFSQAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGAVREVSIHTVRARLRLLYHFSDLMYSSWRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRISTRGRKCKPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEICVEVLKKVVRYREVDEQHQLVQWLWRTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNYMLSRNVDNAEGSDTDY", "length": 4875, "header": "tr|A0A9J7FW57-1|A0A9J7FW57_CRIGR Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Cricetulus griseus OX=10029 GN=Herc1 PE=4 SV=1 CANONICAL=A0A9J7FU62-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62/entry#A0A9J7JNF8-1", "sequence": { "sequence": "MATMVPPVKLKWLEHLNSSWITEDSESIATREGVTVLYSKLVSNKEVVPLPQQVLCLKGPQLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNKYHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMPVSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGADTLGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVHTMEKNKLLSSQEGMISFDCFMAILMQMRRSLGSSADRSQWREPTRTSEGLCSLYEAALCLFEEVCRMASDYSRTCASPDSIQTGDAPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLSLSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLPFPSSREHHNFLKLCLKLLSNHLALALAGGVATSILGRQAGPLRNLLFRLMDSTVPDEIQEVVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVASLLGYSSPSDAADLSTVCMGYGNLSDQPYGPQTCHPDTHLAEILMKTLLRNLGFYTDQAFGELEKNSDKYLFGTSPSENSQPAHLHELLCSLQKQLLAFCHINNITENSSSVALLHKHLQLLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARPLLSYLLDLLPPLDCLNRLLPAAALLEDQELQWPLHGGPEVIDPAGVPLPQPAQSWVWLVDLERTIALLIGRCLGGMLQGSPVSPEEQDTAYWMKTPLFSDGVEMDTPQLDKCMSCLLDVALSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLLDTVSRFVLAALLKHTNLLSQACGESRYQPGKSLSEVYRCVYKVRSRLLACKNLELIQTRSSSRDRWISDNQDSADIDPQEHSFTRTIDEEAEMEEQAERDREDGHPEPDDEEEEREHEVMTAGKIFQCFLSAREVARSRDRDRMSSGAGSGVRADDPPPQSQQERRVSTDLPEGQDVYTAACNSVIHRCALLILGVSPVIDELQKRREEGQLQQPSVSASEGSGLMTRSESLTAESRLVHASPSYRLIKSRSESDLSQPESDEEGYALSGRRNVDLDLASSHRKRGPMHSQLESLSDSWTRLKHTRDWFYNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKEPEESMSTSPQASIIAMEQQQLRAELRLEALHQILTLLSGMEEKGSILLTGSRSSSGFQSSTLLTSVRLQFLAGCFGLGTVGHTGTKGESGRLHHYQDGIRAAKRNIQIEIQVAVHKIYQQLSATLERALQANKHHIEAQQRLLLVTVFALSVHYQPVDVSLAISTGLLNVLSQLCGTDTMLGQPLQLLPKTGVSQLSTALKVASTRLLQILAITTGTYADKLSPKVVQSLLDLLCSQLKNLLSQTGVLFMASFGEGEEVEEEEKKVDSSGETEKKDFRAALRKQHAAELHLGDFLVFLRRVVSSKAIQSKMASPKWTEVLLNIASQKCSSGIPLVGNLRTRLLALHVLEAVLPACESGVEDDQMAQVVERLFSLLSDCMWETPIAQAKHAIQIKEKEQEIKLQKQGELEEEDENLPIQEVSFDPEKAQCCIVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVGVSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFGKNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPICSPVAAVLAEATIQLIRILHRTDRWTYCINKKMMERLHKIKICIKESGQKLKKSRSVQSREENEVREEKENKEEEKGKHNRHGLADLSEPQLRTLCIEVWPVLAVIGGVDAGLRVGGRCVHKQTGRHATLLGVVKEGSTSAKVQWDEAEITISFPTFWSPSDTPLYNLEPCEPLLFDVARFRGLTASVLLDLTYLTGIHEDVGKQSVKRHEKKHRHESEEKVDSEQKPESESMLDVRTGLMSDDAKSQGATSSKSENEIASFSLEPTLPGVESQHQVTEGKRKNHEHTSKTHDIAQSEIRAVQLSYLYLGAMKSLSALLGCSKYAELLLIPKVLAENGHNSDCASSPVVHEDVEMRAALQFLMRHMVKRAVMRSPIKRALGLADLERAQAMIYKLVVHGLLEDQFGGKIKQEIDQPAEESDHAQQAQTPVTTSPSASSTTSFMSSSLEDTTTATTPVTDTETVPASESPGVMPLSLLRQMFSSYPTTTVLPTRRAQTPPISSLPTSPSDEVGRRQSLTSPDSQSTRPANRTALSDPSSRLSTSPPPPAIAVPLLEMGFSLRQIAKAMEATGARGEADAQNITVLAMWMIEHPGHEDEEEPQPSSTADSRHGTTVLGSGGKSNDPCYLQSPGDIPSADAAEMEEGFSESPDNLDHTENAASGSGPPARGRSTVTRRHKFDLAARTLLARAAGLYRSVQAHRNQSRREGISLQQDPGALYDFNLDEELEIDLDDEAMEAMFGQDLTSDNDILGMWIPEHVCESEDREEVVVCELCECNVVSFNQHMKRNHPGCGRSANRQGYRSNGSYVDGWFGGECGSGNPYYLLCGSCREKYLALKTKTKTTNSERYKGQAPDLIGKQDSVYEEDWDMLDIDEDEKLTGEEEFELLAGPLGLNDRRIVPEPVQFPDSDPLGASVAMVTATNSMEETLMQIGCHGSVEKSSSGRVTLGEQAAALANPHDRVVALRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRLMCLAAAGRAGLSTSPSAMASTSERSRGGHSKASKPISCLAYLSTAVGCLASNTPSAAKLLVQLCTQNLISAATGVNLTTVDDPIQRKFLPSFLRGIAEENKLVTSPNFVVTQALVALLADKGAKLRPNYDKSEVEKKGFIAQLYAHPSYDPSAVGPLELANALAACCLSSRLSSQHRQWAAQQLVRTLAAHDRDNQTAPQTLADMGGDLRKCSFIKLEAHQNRVMTCVWCNKKGLLATSGNDGTIRVWNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEKMVNIWQVNGGKGLVDIQPHWVSALAWPEEGPATAWSGESPELLLVGRMDGSLGLIEVVDVSTMHRRELEHCYRKDVSVTCIAWFSEDRPFAVGYFDGKLLMGTKEPLEKGGIVLIDAHKETLVSMKWDPTGHILMTCAKEENVKLWGPVSGCWRCLHSLCHPSTVNGIAWCSLPGKGSKLQLLMATGCQNGLVCVWRIPQDTTQTSMTCSEGWWDQESNCQDGCRKSAGAKCVYQLRGHITPVRTVAFSSDGLALVSGGLGGLMNIWSLRDGSVLQTVVIGSGAIQTTVWIPEVGVAACSNRSKDVLVVNCTAEWASANHVLATCRTALKQQGILGLNMAPCMRAFLERLPMMLQEQYAYEKPHVVCGDQLVHSPYMQCLASLAVGLHLDQLLCSPPVPPHHQSCLPDPASWNPNEWAWLECFSTTIKAAEALTNGAQFPESFTVPDLEPVPEDELVLLMDNSKWINGMDEQIMSWATSRPEDWHLGGKCDVYLWGAGRHGQLAEAGRNVMVPATAPSFSQAQQVICGQNCTFVIQANGTVLACGEGSYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIEDVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNIRQISAGRCHSAAWTAPPVPPRAPGVSVPLQLGLPDTVPPQYGAVREVSIHTVRARLRLLYHFSDLMYSSWRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQITVKRISTRGRKCKPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKKPLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSFVGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEICVEVLKKVVRYREVDEQHQLVQWLWRTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNYMLSRNVDNAEGSDTDY", "length": 4869, "header": "tr|A0A9J7JNF8-1|A0A9J7JNF8_CRIGR Computationally mapped isoform of HECT-type E3 ubiquitin transferase OS=Cricetulus griseus OX=10029 GN=Herc1 PE=4 SV=1 CANONICAL=A0A9J7FU62-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRR2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRR2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772726", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772726", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1004, "end_pos": 1006, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1008, "end_pos": 1010, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1043, "end_pos": 1045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1256, "end_pos": 1258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1571, "end_pos": 1573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2731, "end_pos": 2733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2782, "end_pos": 2784, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2903, "end_pos": 2905, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3012, "end_pos": 3014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3298, "end_pos": 3300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3417, "end_pos": 3419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3471, "end_pos": 3473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3823, "end_pos": 3825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3832, "end_pos": 3834, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4052, "end_pos": 4054, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4060, "end_pos": 4062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4185, "end_pos": 4187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4211, "end_pos": 4213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4238, "end_pos": 4240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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{ "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 2000, "end_pos": 2191, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FU62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU62" }, { "id": "PS50237", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50237" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HECT", "eco_id": "ECO_0000259", "start_pos": 4516, "end_pos": 4863, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.26", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", 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"https://www.uniprot.org/uniprotkb/A0A9J7GTD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDWLMGSQNEGADLVAFQKCQFKIHISGRALVAHTFNPSIREAEAGGSLKSKAKPNGKKTASEEKKVYLEPEHTKSRITDFEFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVKKICKYLFHVLGHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAVMDDLTEVLCSSPGSSGATGDGASSGASGAQNHVKER", "length": 278, "header": "tr|A0A9J7FRS7-1|A0A9J7FRS7_CRIGR Isoform 1 of MOB kinase activator 2 OS=Cricetulus griseus OX=10029 GN=Mob2 PE=3 SV=1 CANONICAL=A0A9J7FRS7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M7E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7/entry#A0A8C2M7E4-1", "sequence": { "sequence": "MDWLMGKSKAKPNGKKTASEEKKVYLEPEHTKSRITDFEFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVKKICKYLFHVLGHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAVMDDLTEVLCSSPGSSGATGDGASSGASGAQNHVKER", "length": 235, "header": "tr|A0A8C2M7E4-1|A0A8C2M7E4_CRIGR Computationally mapped isoform of MOB kinase activator 2 OS=Cricetulus griseus OX=10029 GN=Mob2 PE=3 SV=1 CANONICAL=A0A9J7FRS7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7/entry#A0A9J7FRS7-1", "sequence": { "sequence": "MDWLMGSQNEGADLVAFQKCQFKIHISGRALVAHTFNPSIREAEAGGSLKSKAKPNGKKTASEEKKVYLEPEHTKSRITDFEFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVKKICKYLFHVLGHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAVMDDLTEVLCSSPGSSGATGDGASSGASGAQNHVKER", "length": 278, "header": "tr|A0A9J7FRS7-1|A0A9J7FRS7_CRIGR Isoform 1 of MOB kinase activator 2 OS=Cricetulus griseus OX=10029 GN=Mob2 PE=3 SV=1 CANONICAL=A0A9J7FRS7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7/entry#A0A9J7FRU8-1", "sequence": { "sequence": "MYVSLGFAQAPCCCLQSTKWSQQPCFSAAGYRKSKAKPNGKKTASEEKKVYLEPEHTKSRITDFEFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVKKICKYLFHVLGHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAVMDDLTEVLCSSPGSSGATGDGASSGASGAQNHVKER", "length": 261, "header": "tr|A0A9J7FRU8-1|A0A9J7FRU8_CRIGR Computationally mapped isoform of MOB kinase activator 2 OS=Cricetulus griseus OX=10029 GN=Mob2 PE=3 SV=1 CANONICAL=A0A9J7FRS7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7/entry#A0A9J7FTN1-1", "sequence": { "sequence": "MDWLMGSQNEGADLVAFQKCQFKIHISGRALVAHTFNPSIREAEAGGSLKSKAKPNGKKTASEEKKVYLEPEHTKSRITDFEFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYENSPARSSPW", "length": 185, "header": "tr|A0A9J7FTN1-1|A0A9J7FTN1_CRIGR Computationally mapped isoform of MOB kinase activator 2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Mob2 PE=4 SV=1 CANONICAL=A0A9J7FRS7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GTD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7/entry#A0A9J7GTD3-1", "sequence": { "sequence": "MAVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVKKICKYLFHVLGHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAVMDDLTEVLCSSPGSSGATGDGASSGASGAQNHVKER", "length": 150, "header": "tr|A0A9J7GTD3-1|A0A9J7GTD3_CRIGR Computationally mapped isoform of MOB kinase activator 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mob2 PE=4 SV=1 CANONICAL=A0A9J7FRS7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767788", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767788", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A9J7FRU8", "database": 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"https://www.uniprot.org/uniprotkb/A0A8C2M7E4" }, { "id": "PIRSR605301-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR605301-1" } ], "binding_site_uniprot": 83, "amino_acid": "Phe", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 83, "end_pos": 83, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 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"A0A9J7FRT4", "uniprot_id": "A0A9J7FRT4_CRIGR", "mass": { "chemical_mass": 150213.0, "monoisotopic_mass": 150213.0 }, "refseq": { "ac": "XP_027266825", "name": "inhibitor of Bruton tyrosine kinase isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266825" }, "gene_names": [ { "name": "LOC100751546", "type": "recommended", "evidence": [ { "id": "A0A9J7FRT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ] }, { "name": "LOC100751546", "type": "synonym", "evidence": [ { "id": "XP_027266825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266825" } ] } ], "protein_names": [ { "name": "Inhibitor of Bruton tyrosine kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7FRT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4/entry#names_and_taxonomy" } ] }, { "name": "inhibitor of Bruton tyrosine kinase isoform X6", "type": "synonym", "evidence": [ { "id": "XP_027266825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266825" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266825" } ] }, { "annotation": "Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4#function" }, { "database": "UniProtKB", "id": "ARBA00054263", "url": "https://www.uniprot.org/uniprotkb/ARBA00054263#function" }, { "database": "UniProtKB", "id": "A0A9J7FTU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTU7#function" }, { "database": "UniProtKB", "id": "A0A9J7FVS8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS8#function" }, { "database": "UniProtKB", "id": "A0A8C2LM49", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM49#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100751546", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4", "locus": {} } ], "crossref": [ { "id": "cd18301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18302", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18302", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18500", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18500", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751546", "url": "https://www.ncbi.nlm.nih.gov/gene/100751546", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751546", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751546", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FRT4", "url": "https://www.orthodb.org/?gene=A0A9J7FRT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22872:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22872:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266825", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LM49", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LM49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVS8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMDSATPDCTSKCRSLKHALDVLSVVTKGSENQIKAFLSSHCHNAATVKDAFGRNALHLVSSCGKKGVLDWLIEKGVDLLVKDKESGWTALHRSIFYGHIDCTWSLLKHGVSLYVQDKEGLSPLDLLMKDRPNHVVFKNTDPTEVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLIGHNCSQVAAAKDHTVVLTEDGCVFTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGKTVIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDISVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKVDPEHLTENGGQKICILAMDGAGRVFCWRSLSSSLKQCRWAYPRQVSISDIALNRNEILFVTQDGEGFKGKWFEDKRKTSEKKADILPNLHHSSSDVSCVSDTNSVYERIRLEKLPFAHRAVSVSTDASGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDNIHDVTFQVGNRLFPAHKYVLAVRSDFFQKLFLSDGTPSELTDVYRKDEDAAGCHLFVVEKVHPDLFEYLLQFMYTDTCDFLTHGFKPRILMNKKPEDCKGSSDSHMNKMNCHMDDNQKAAFEVYKSNQAHTISERQKSKHKSSKKGKGVGEDDPVRMLQNVAKKFGLSNLSSRLDGVRFENEKINVIAKKTGNKLKLSQKKCSFLYDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSSSWIEASSCAALEMPIESEILKVVLDYLYTDEALVIKESQNVDFICSVLVVADQLLITRLKEVCEGALTEKLTLKNAAMLLEFAAMYNAQQLKLSCLQFIGLNMAALLEARSLDVLSEDVLKDLSIFYRKMIPAMERRVITPYQDGPDISYMQVDDGDVFFKEEINMEPNYSETMFKKAKTRAKKKPRKRSDSSGGYNLSDIIQSPPSAGLLKSGKTNSVESLPELLTSDSEGSYAGVGSPRDLQSPDFTAGFHLDKVEVGLGKAKPYVNGTPPPCAREDFKPWEKSPTSKSAPQFIPRDRVDTAGSSSWVTGSFSPTSPPVVDFRTIMETEESRQKYGAVPKLNLGKIISHGVKLSQRQRKMIALTTKENNSGTNSMEPILTAPSKSLKPANAWASLHSPSSKSFRDFLLGEKKPVTGHGSVDHVKKVGFKGIENSQALNVVRCSTHGSPGLESNHVSDFPLLESPNPWLSSSLAASTAVAPVTFASIVEEERQQEAALIRSREKPLALIQVEEHAIQDLLVFYEAFGNPDEFVVVERTAQGPLAAPMWNKHGC", "length": 1356, "header": "tr|A0A9J7FRT4-1|A0A9J7FRT4_CRIGR Isoform 1 of Inhibitor of Bruton tyrosine kinase OS=Cricetulus griseus OX=10029 GN=LOC100751546 PE=4 SV=1 CANONICAL=A0A9J7FRT4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LM49-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4/entry#A0A8C2LM49-1", "sequence": { "sequence": "MMDSATPDCTSKCRSLKHALDVLSVVTKGSENQIKAFLSSHCHNAATVKDAFGRNALHLVSSCGKKGVLDWLIEKGVDLLVKDKESGWTALHRSIFYGHIDCTWSLLKHGVSLYVQDKEGLSPLDLLMKDRPNHVVFKNTDPTEVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLIGHNCSQVAAAKDHTVVLTEDGCVFTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGKTVIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDISVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKVDPEHLTENGGQKICILAMDGAGRVFCWRSLSSSLKQCRWAYPRQVSISDIALNRNEILFVTQDGEGFKGKWFEDKRKTSEKKADILPNLHHSSSDVSCVSDTNSVYERIRLEKLPFAHRAVSVSTDASGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDNIHDVTFQVGNRLFPAHKYVLAVRSDFFQKLFLSDGTPSELTDVYRKDEDAAGCHLFVVEKVHPDLFEYLLQFMYTDTCDFLTHGFKPRILMNKKPEDCKGSSDSHMNKMNCHMDDNQKAAFEVYKSNQAHTISERQKSKHKSSKKGKGVGEDDPVRMLQNVAKKFGLSNLSSRLDGVRFENEKINVIAKKTGNKLKLSQKKCSFLYDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSSSWIEASSCAALEMPIESEILKVVLDYLYTDEALVIKESQNVDFICSVLVVADQLLITRLKEVCEGALTEKLTLKNAAMLLEFAAMYNAQQLKLSCLQFIGLNMAALLEARSLDVLSEDVLKDLSIFYRKMIPAMERRVITPYQDGPDISYMQVDDGDVFFKEEINMEPNYSETMFKKAKTRAKKKPRKRSDSSGGYNLSDIIQSPPSAGLLKSGKTNSVESLPELLTSDSEGSYAGVGSPRDLQSPDFTAGFHLDKVEGKAKPYVNGTPPPCAREDFKPWEKSPTSKSAPQFIPRDRVDTAGSSSWVTGSFSPTSPPVVDFRTIMETEESRQKYGAVPKLNLGKIISHGVKLSQRQRKMIALTTKENNSGTNSMEPILTAPSKSLKPANAWASLHSPSSKSFRDFLLGEKKPVTGHGSVDHVKKVGFKGIENSQALNVVRCSTHGSPGLESNHVSDFPLLESPNPWLSSSLAASTAVAPVTFASIVEEERQQEAALIRSREKPLALIQVEEHAIQDLLVFYEAFGNPDEFVVVERTAQGPLAAPMWNKHGC", "length": 1353, "header": "tr|A0A8C2LM49-1|A0A8C2LM49_CRIGR Computationally mapped isoform of Inhibitor of Bruton tyrosine kinase OS=Cricetulus griseus OX=10029 GN=LOC100751546 PE=4 SV=1 CANONICAL=A0A9J7FRT4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4/entry#A0A9J7FRT4-1", "sequence": { "sequence": "MMDSATPDCTSKCRSLKHALDVLSVVTKGSENQIKAFLSSHCHNAATVKDAFGRNALHLVSSCGKKGVLDWLIEKGVDLLVKDKESGWTALHRSIFYGHIDCTWSLLKHGVSLYVQDKEGLSPLDLLMKDRPNHVVFKNTDPTEVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLIGHNCSQVAAAKDHTVVLTEDGCVFTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGKTVIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDISVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKVDPEHLTENGGQKICILAMDGAGRVFCWRSLSSSLKQCRWAYPRQVSISDIALNRNEILFVTQDGEGFKGKWFEDKRKTSEKKADILPNLHHSSSDVSCVSDTNSVYERIRLEKLPFAHRAVSVSTDASGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDNIHDVTFQVGNRLFPAHKYVLAVRSDFFQKLFLSDGTPSELTDVYRKDEDAAGCHLFVVEKVHPDLFEYLLQFMYTDTCDFLTHGFKPRILMNKKPEDCKGSSDSHMNKMNCHMDDNQKAAFEVYKSNQAHTISERQKSKHKSSKKGKGVGEDDPVRMLQNVAKKFGLSNLSSRLDGVRFENEKINVIAKKTGNKLKLSQKKCSFLYDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSSSWIEASSCAALEMPIESEILKVVLDYLYTDEALVIKESQNVDFICSVLVVADQLLITRLKEVCEGALTEKLTLKNAAMLLEFAAMYNAQQLKLSCLQFIGLNMAALLEARSLDVLSEDVLKDLSIFYRKMIPAMERRVITPYQDGPDISYMQVDDGDVFFKEEINMEPNYSETMFKKAKTRAKKKPRKRSDSSGGYNLSDIIQSPPSAGLLKSGKTNSVESLPELLTSDSEGSYAGVGSPRDLQSPDFTAGFHLDKVEVGLGKAKPYVNGTPPPCAREDFKPWEKSPTSKSAPQFIPRDRVDTAGSSSWVTGSFSPTSPPVVDFRTIMETEESRQKYGAVPKLNLGKIISHGVKLSQRQRKMIALTTKENNSGTNSMEPILTAPSKSLKPANAWASLHSPSSKSFRDFLLGEKKPVTGHGSVDHVKKVGFKGIENSQALNVVRCSTHGSPGLESNHVSDFPLLESPNPWLSSSLAASTAVAPVTFASIVEEERQQEAALIRSREKPLALIQVEEHAIQDLLVFYEAFGNPDEFVVVERTAQGPLAAPMWNKHGC", "length": 1356, "header": "tr|A0A9J7FRT4-1|A0A9J7FRT4_CRIGR Isoform 1 of Inhibitor of Bruton tyrosine kinase OS=Cricetulus griseus OX=10029 GN=LOC100751546 PE=4 SV=1 CANONICAL=A0A9J7FRT4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4/entry#A0A9J7FTU7-1", "sequence": { "sequence": "MMDSATPDCTSKCRSLKHALDVLSVVTKGSENQIKAFLSSHCHNAATVKDAFGRNALHLVSSCGKKGVLDWLIEKGVDLLVKDKESGWTALHRSIFYGHIDCTWSLLKHGVSLYVQDKEGLSPLDLLMKDRPNHVVFKNTDPTEVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLIGHNCSQVAAAKDHTVVLTEDGCVFTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGKTVIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDISVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKVDPEHLTENGGQKICILAMDGAGRVFCWRSLSSSLKQCRWAYPRQVSISDIALNRNEILFVTQDGEGFKGKWFEDKRKTSEKKDILPNLHHSSSDVSCVSDTNSVYERIRLEKLPFAHRAVSVSTDASGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDNIHDVTFQVGNRLFPAHKYVLAVRSDFFQKLFLSDGTPSELTDVYRKDEDAAGCHLFVVEKVHPDLFEYLLQFMYTDTCDFLTHGFKPRILMNKKPEDCKGSSDSHMNKMNCHMDDNQKAAFEVYKSNQAHTISERQKSKHKSSKKGKGVGEDDPVRMLQNVAKKFGLSNLSSRLDGVRFENEKINVIAKKTGNKLKLSQKKCSFLYDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSSSWIEASSCAALEMPIESEILKVVLDYLYTDEALVIKESQNVDFICSVLVVADQLLITRLKEVCEGALTEKLTLKNAAMLLEFAAMYNAQQLKLSCLQFIGLNMAALLEARSLDVLSEDVLKDLSIFYRKMIPAMERRVITPYQDGPDISYMQVDDGDVFFKEEINMEPNYSETMFKKAKTRAKKKPRKRSDSSGGYNLSDIIQSPPSAGLLKSGKTNSVESLPELLTSDSEGSYAGVGSPRDLQSPDFTAGFHLDKVEVGLGKAKPYVNGTPPPCAREDFKPWEKSPTSKSAPQFIPRDRVDTAGSSSWVTGSFSPTSPPVVDFRTIMETEESRQKYGAVPKLNLGKIISHGVKLSQRQRKMIALTTKENNSGTNSMEPILTAPSKSLKPANAWASLHSPSSKSFRDFLLGEKKPVTGHGSVDHVKKVGFKGIENSQALNVVRCSTHGSPGLESNHVSDFPLLESPNPWLSSSLAASTAVAPVTFASIVEEERQQEAALIRSREKPLALIQVEEHAIQDLLVFYEAFGNPDEFVVVERTAQGPLAAPMWNKHGC", "length": 1355, "header": "tr|A0A9J7FTU7-1|A0A9J7FTU7_CRIGR Computationally mapped isoform of Inhibitor of Bruton tyrosine kinase OS=Cricetulus griseus OX=10029 GN=LOC100751546 PE=4 SV=1 CANONICAL=A0A9J7FRT4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4/entry#A0A9J7FVS8-1", "sequence": { "sequence": "MMDSATPDCTSKCRSLKHALDVLSVVTKGSENQIKAFLSSHCHNAATVKDAFGRNALHLVSSCGKKGVLDWLIEKGVDLLVKDKESGWTALHRSIFYGHIDCTWSLLKHGVSLYVQDKEGLSPLDLLMKDRPNHVVFKNTDPTEVYTWGDNTNFTLGHGSQNSKHHPELVDLFSRSGVYVKQVVLCKFHSVFLSQKGQVYTCGHGRGGRLGHGDEQTCLVPRLVEGLIGHNCSQVAAAKDHTVVLTEDGCVFTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKGKTVIGVAAGRFHTVLWTREAVYTLGLNGGQLGHLLDPNGEKCVTTPRQVSALHHKDISVSLVAASDGATVCVTTRGDIYLLADYQCKKMATKQLNLKKVLVSGGCMEYKVDPEHLTENGGQKICILAMDGAGRVFCWRSLSSSLKQCRWAYPRQVSISDIALNRNEILFVTQDGEGFKGKWFEDKRKTSEKKDILPNLHHSSSDVSCVSDTNSVYERIRLEKLPFAHRAVSVSTDASGCNFAILQSDPKTSLYEIPVVSSSSFFEEFGKLLRETDEMDNIHDVTFQVGNRLFPAHKYVLAVRSDFFQKLFLSDGTPSELTDVYRKDEDAAGCHLFVVEKVHPDLFEYLLQFMYTDTCDFLTHGFKPRILMNKKPEDCKGSSDSHMNKMNCHMDDNQKAAFEVYKSNQAHTISERQKSKHKSSKKGKGVGEDDPVRMLQNVAKKFGLSNLSSRLDGVRFENEKINVIAKKTGNKLKLSQKKCSFLYDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSSSWIEASSCAALEMPIESEILKVVLDYLYTDEALVIKESQNVDFICSVLVVADQLLITRLKEVCEGALTEKLTLKNAAMLLEFAAMYNAQQLKLSCLQFIGLNMAALLEARSLDVLSEDVLKDLSIFYRKMIPAMERRVITPYQDGPDISYMQVDDGDVFFKEEINMEPNYSETMFKKAKTRAKKKPRKRSDSSGGYNLSDIIQSPPSAGLLKSGKTNSVESLPELLTSDSEGSYAGVGSPRDLQSPDFTAGFHLDKVEGKAKPYVNGTPPPCAREDFKPWEKSPTSKSAPQFIPRDRVDTAGSSSWVTGSFSPTSPPVVDFRTIMETEESRQKYGAVPKLNLGKIISHGVKLSQRQRKMIALTTKENNSGTNSMEPILTAPSKSLKPANAWASLHSPSSKSFRDFLLGEKKPVTGHGSVDHVKKVGFKGIENSQALNVVRCSTHGSPGLESNHVSDFPLLESPNPWLSSSLAASTAVAPVTFASIVEEERQQEAALIRSREKPLALIQVEEHAIQDLLVFYEAFGNPDEFVVVERTAQGPLAAPMWNKHGC", "length": 1352, "header": "tr|A0A9J7FVS8-1|A0A9J7FVS8_CRIGR Computationally mapped isoform of Inhibitor of Bruton tyrosine kinase OS=Cricetulus griseus OX=10029 GN=LOC100751546 PE=4 SV=1 CANONICAL=A0A9J7FRT4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751546", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751546", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ], "pmid": "" }, { "name": "protein tyrosine kinase inhibitor activity", "id": "GO:0030292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030292", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1071, "end_pos": 1073, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1172, "end_pos": 1174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 733, "end_pos": 735, "annotation": "n_glycosylation_sequon" }, { "start_pos": 971, "end_pos": 973, "annotation": "n_glycosylation_sequon" }, { "start_pos": 999, "end_pos": 1001, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FRT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT4" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 566, "end_pos": 646, "start_aa": "His", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1071, "end_pos": 1073 }, { "start_pos": 1172, "end_pos": 1174 }, { "start_pos": 153, "end_pos": 155 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 733, "end_pos": 735 }, { "start_pos": 971, "end_pos": 973 }, { "start_pos": 999, "end_pos": 1001 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FRT7-1", "uniprot_ac": "A0A9J7FRT7", "uniprot_id": "A0A9J7FRT7_CRIGR", "mass": { "chemical_mass": 42275.0, "monoisotopic_mass": 42275.0 }, "refseq": { "ac": "XP_027265083", "name": "serpin B9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265083" }, "gene_names": [ { "name": "LOC100757562", "type": "recommended", "evidence": [ { "id": "A0A9J7FRT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7" } ] }, { "name": "LOC100757562", "type": "synonym", "evidence": [ { "id": "XP_027265083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265083" } ] } ], "protein_names": [ { "name": "Leukocyte elastase inhibitor", "type": "recommended", "evidence": [ { "id": "A0A9J7FRT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7/entry#names_and_taxonomy" } ] }, { "name": "Serpin B1", "type": "synonym", "evidence": [ { "id": "A0A9J7FRT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7/entry#names_and_taxonomy" } ] }, { "name": "serpin B9", "type": "synonym", "evidence": [ { "id": "XP_027265083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265083" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265083" } ] }, { "annotation": "Regulates the activity of the neutrophil proteases.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7#function" }, { "database": "UniProtKB", "id": "ARBA00059846", "url": "https://www.uniprot.org/uniprotkb/ARBA00059846#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100757562", "url": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FRT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTLCEANGSFAIRLLKTLCQNNPSENVCYSPVSISSALAMVLLGAKGDTAVQITQALGLNTEEDIHQGFQGLLSNLNKPNRKYSLRVANRLFAENTCELIPAFKESCLQFYDSGMEQLSFVKAPEESRKHINTWVSKQTEGKIPELLSGCSVDSETRLVFVNALYFKGRWHQQFHKDCTMEMPFKINKKEKRPVQMMCREDTFHLAYVNEVQAQVLVMPYEGMELSMVVLLPDDGVDLSKLENSLTFEKLTAWTRPDFMKSTDVEVFLPKFKLQEDYDMESVFQQLGMVDVFHRDKADLSGMSPERDLCVSKFVHKSVVEVNEEGTEAAAASAVIEFCCASVVPTFCADHPFLFFIRHNKTNSLLFCGRFSSP", "length": 374, "header": "tr|A0A9J7FRT7-1|A0A9J7FRT7_CRIGR Isoform 1 of Leukocyte elastase inhibitor OS=Cricetulus griseus OX=10029 GN=LOC100757562 PE=3 SV=1 CANONICAL=A0A9J7FRT7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7/entry#A0A9J7FRT7-1", "sequence": { "sequence": "MNTLCEANGSFAIRLLKTLCQNNPSENVCYSPVSISSALAMVLLGAKGDTAVQITQALGLNTEEDIHQGFQGLLSNLNKPNRKYSLRVANRLFAENTCELIPAFKESCLQFYDSGMEQLSFVKAPEESRKHINTWVSKQTEGKIPELLSGCSVDSETRLVFVNALYFKGRWHQQFHKDCTMEMPFKINKKEKRPVQMMCREDTFHLAYVNEVQAQVLVMPYEGMELSMVVLLPDDGVDLSKLENSLTFEKLTAWTRPDFMKSTDVEVFLPKFKLQEDYDMESVFQQLGMVDVFHRDKADLSGMSPERDLCVSKFVHKSVVEVNEEGTEAAAASAVIEFCCASVVPTFCADHPFLFFIRHNKTNSLLFCGRFSSP", "length": 374, "header": "tr|A0A9J7FRT7-1|A0A9J7FRT7_CRIGR Isoform 1 of Leukocyte elastase inhibitor OS=Cricetulus griseus OX=10029 GN=LOC100757562 PE=3 SV=1 CANONICAL=A0A9J7FRT7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FRT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRT7" }, { "id": "SM00093", "database": "SMART", "url": 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"summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267227" }, "gene_names": [ { "name": "LOC100774856", "type": "recommended", "evidence": [ { "id": "A0A9J7FRX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ] }, { "name": "LOC100774856", "type": "synonym", "evidence": [ { "id": "XP_027267227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267227" } ] } ], "protein_names": [ { "name": "Zinc finger protein 26 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7FRX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 26 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027267227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267227" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267227" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7FWB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWB4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100774856", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7", "locus": {} } ], "crossref": [ { "id": "A0A9J7FRX7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FRX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774856", "url": "https://www.ncbi.nlm.nih.gov/gene/100774856", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774856", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774856", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FRX7", "url": "https://www.orthodb.org/?gene=A0A9J7FRX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267227", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSVTFEDVAVYFTKEEWTLLDGFQRSLYREVMLENYQNLASAEVKMDLETKETELQLDSYWSDISNETQLARLTKVGSHNGGELCDSNNIGKFFSEYPCLQTYMNIHNTKKISEYNWYRKDLLPSFKKTSTEEKLSVLIQCEEAFALIRSIPYQRACIQDSSFECSSFGKAFDNRLQLKAHNKDHSKENFYEWEQSKKAFTESTNCCALEKCYEGKECGKAVTAQAGLTTHVRSHKKQKSYECTECGKVFGKCSGLIEHVRSHTGEKPFKCNHCEKAFASSSYLTAHLRTHTGEKPFECTVCGKAFTRSSYLRIHMRTHTGEKPYNCKECGKTFAVRSCLNTHSRTHTGEKPYDCKECEKAFTSFYQLTEHMKIHTGEKPFECQVCTKSFRNSSCLKKHFQIHTGIKPFQCKDCGKAFSGRTSFTTHVLTHTGEKPYECKECGKAFRTSSGLIEHIRSHTGEKPFECYQCGKAFASSSYLTAHLRTHTGEKPFECTVCGKAFTRSSYLCRHMKTHSGEKPYVCKDCGNAVNGCSCFNRHIKTHNGENPYLY", "length": 552, "header": "tr|A0A9J7FRX7-1|A0A9J7FRX7_CRIGR Isoform 1 of Zinc finger protein 26 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100774856 PE=3 SV=1 CANONICAL=A0A9J7FRX7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7/entry#A0A9J7FRX7-1", "sequence": { "sequence": "MDSVTFEDVAVYFTKEEWTLLDGFQRSLYREVMLENYQNLASAEVKMDLETKETELQLDSYWSDISNETQLARLTKVGSHNGGELCDSNNIGKFFSEYPCLQTYMNIHNTKKISEYNWYRKDLLPSFKKTSTEEKLSVLIQCEEAFALIRSIPYQRACIQDSSFECSSFGKAFDNRLQLKAHNKDHSKENFYEWEQSKKAFTESTNCCALEKCYEGKECGKAVTAQAGLTTHVRSHKKQKSYECTECGKVFGKCSGLIEHVRSHTGEKPFKCNHCEKAFASSSYLTAHLRTHTGEKPFECTVCGKAFTRSSYLRIHMRTHTGEKPYNCKECGKTFAVRSCLNTHSRTHTGEKPYDCKECEKAFTSFYQLTEHMKIHTGEKPFECQVCTKSFRNSSCLKKHFQIHTGIKPFQCKDCGKAFSGRTSFTTHVLTHTGEKPYECKECGKAFRTSSGLIEHIRSHTGEKPFECYQCGKAFASSSYLTAHLRTHTGEKPFECTVCGKAFTRSSYLCRHMKTHSGEKPYVCKDCGNAVNGCSCFNRHIKTHNGENPYLY", "length": 552, "header": "tr|A0A9J7FRX7-1|A0A9J7FRX7_CRIGR Isoform 1 of Zinc finger protein 26 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100774856 PE=3 SV=1 CANONICAL=A0A9J7FRX7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7/entry#A0A9J7FWB4-1", "sequence": { "sequence": "MDSVTFEDVAVYFTKEEWTLLDGFQRSLYREVMLENYQNLASAEVKMDLETKETELQLDSYWSDISNETQLARLTKVGSHNGGELCDSNNIGKFFSEYPCLQTYMNIHNTKKISEYNWYRKDLLPSFKKTSTEEKLSVLIQCEEAFALIRSIPYQRACIQDSSFECSSFGKAFDNRLQLKAHNKDHSKENFYEWEQSKKAFTESTNCCALEKCYEAHLRTHTGEKPFECTVCGKAFTRSSYLRIHMRTHTGEKPYNCKECGKTFAVRSCLNTHSRTHTGEKPYDCKECEKAFTSFYQLTEHMKIHTGEKPFECQVCTKSFRNSSCLKKHFQIHTGIKPFQCKDCGKAFSGRTSFTTHVLTHTGEKPYECKECGKAFRTSSGLIEHIRSHTGEKPFECYQCGKAFASSSYLTAHLRTHTGEKPFECTVCGKAFTRSSYLCRHMKTHSGEKPYVCKDCGNAVNGCSCFNRHIKTHNGENPYLY", "length": 481, "header": "tr|A0A9J7FWB4-1|A0A9J7FWB4_CRIGR Computationally mapped isoform of Zinc finger protein 121 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100774856 PE=3 SV=1 CANONICAL=A0A9J7FRX7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774856", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774856", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 393, "end_pos": 395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FRX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 164, "end_pos": 191, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FRX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRX7" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 77, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 393, "end_pos": 395 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FRY8-1", "uniprot_ac": "A0A9J7FRY8", "uniprot_id": "A0A9J7FRY8_CRIGR", "mass": { "chemical_mass": 66274.0, "monoisotopic_mass": 66274.0 }, "refseq": { "ac": "XP_007638706", "name": "zinc finger protein 121-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638706" }, "gene_names": [ { "name": "LOC103161690", "type": "recommended", "evidence": [ { "id": "A0A9J7FRY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRY8" } ] }, { "name": "LOC103161690", "type": "synonym", "evidence": [ { "id": "XP_007638706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638706" } ] } ], "protein_names": [ { "name": "Zinc finger protein 121-like", "type": "synonym", "evidence": [ { "id": "A0A9J7FRY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRY8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 121-like", "type": "synonym", "evidence": [ { "id": "XP_007638706", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638706" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613752.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007638706.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007638706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638706" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRY8#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRY8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103161690", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRY8", "locus": {} } ], "crossref": [ { "id": "A0A9J7FRY8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FRY8", "database": "AlphaFoldDB", "categories": [] }, { "id": "103161690", "url": "https://www.ncbi.nlm.nih.gov/gene/103161690", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103161690", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103161690", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FRY8", "url": "https://www.orthodb.org/?gene=A0A9J7FRY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF75", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF75", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007638706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638706", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FRY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQHKNIFREHSYFKRHMKTENSNACDSSQYGKHFLTLHKKTSMRQELSVLSQYAGDFVTPNVTRQRTDLQDKPVECTDFLNQSYFKVHMRMYNGEKFCELTRFAGDFTCSTSGALPIQKYTIKAYECKICGKVFGCSSNLNNHMRTHTGEKPYECKVCGKIFGYSSNLNSHIQTHTREKLYECKICKKPFTTSSSLTEHFRINTGEKPYKCIECGKAFTKHSGLSTHIQKHVGQKPYVCKLCGRSFTISSNLTEHLRSHTGEKPYECKECGKAFQASSYLHKHLRTHTGEKPYKCAKCGKAFPTSSYLRKHVRTHSAEKPYKCRECGKSYKRCYLLNEHLKTCMVDKPFDCKVCGKSFRSFACRNKHIRLHTGIRPYKCKYCGKDFTVSSSLTEHIRTHTGERPYECKECGKAFTTSSCLIIHKRTHTGEKPYECKQCGKAYKRCYLLTEHVKTHTGEKSFECKVCGKLFGNSSCLNKHIRIHTGIKPNKCKYCGKEFTVSSSLAERVRTHMGEKPYKCKECGKAFITSSNLYHHAQICDREVSSKYQECGKNYSKFYQLTEHLINKPEQKSFE", "length": 574, "header": "tr|A0A9J7FRY8-1|A0A9J7FRY8_CRIGR Isoform 1 of Zinc finger protein 121-like OS=Cricetulus griseus OX=10029 GN=LOC103161690 PE=3 SV=1 CANONICAL=A0A9J7FRY8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRY8/entry#A0A9J7FRY8-1", "sequence": { "sequence": "MQHKNIFREHSYFKRHMKTENSNACDSSQYGKHFLTLHKKTSMRQELSVLSQYAGDFVTPNVTRQRTDLQDKPVECTDFLNQSYFKVHMRMYNGEKFCELTRFAGDFTCSTSGALPIQKYTIKAYECKICGKVFGCSSNLNNHMRTHTGEKPYECKVCGKIFGYSSNLNSHIQTHTREKLYECKICKKPFTTSSSLTEHFRINTGEKPYKCIECGKAFTKHSGLSTHIQKHVGQKPYVCKLCGRSFTISSNLTEHLRSHTGEKPYECKECGKAFQASSYLHKHLRTHTGEKPYKCAKCGKAFPTSSYLRKHVRTHSAEKPYKCRECGKSYKRCYLLNEHLKTCMVDKPFDCKVCGKSFRSFACRNKHIRLHTGIRPYKCKYCGKDFTVSSSLTEHIRTHTGERPYECKECGKAFTTSSCLIIHKRTHTGEKPYECKQCGKAYKRCYLLTEHVKTHTGEKSFECKVCGKLFGNSSCLNKHIRIHTGIKPNKCKYCGKEFTVSSSLAERVRTHMGEKPYKCKECGKAFITSSNLYHHAQICDREVSSKYQECGKNYSKFYQLTEHLINKPEQKSFE", "length": 574, "header": "tr|A0A9J7FRY8-1|A0A9J7FRY8_CRIGR Isoform 1 of Zinc finger protein 121-like OS=Cricetulus griseus OX=10029 GN=LOC103161690 PE=3 SV=1 CANONICAL=A0A9J7FRY8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003613752.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007638691", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638691" } ] }, { "annotation": "Electron donor, of the core iron-sulfur cluster (ISC) assembly complex, that acts to reduce the persulfide into sulfide during [2Fe-2S] clusters assembly on the scaffolding protein ISCU. The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner. Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly. Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5. 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CANONICAL=A0A9J7FUD2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FUD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUD2/entry#A0A9J7FUD2-1", "sequence": { "sequence": "MHTSRTHTIRLKAWGGCVQPQFQAGSQAGSWYITSDLILRSNTAITVAAYALSMLGLPVTWPVMAASMARGVSARVLLRAAGGSWGTWAGHVAVTSRTLGTTGTQARVGVRLAARPHPLTRSCFPGQRRAGEDEADGPELPRDAVNVVFVDRSGRRIPVRGRVGDNVLHLAQRHGVDLEGACEASLACSTCHVYVSEAHLDLLPPPEEREDDMLDMAPLLQENSRLGCQIVLTPELEGVEFALPKVTRNFYVDGHIPKPH", "length": 260, "header": "tr|A0A9J7FUD2-1|A0A9J7FUD2_CRIGR Isoform 1 of Ferredoxin-2, mitochondrial OS=Cricetulus griseus OX=10029 GN=Fdx2 PE=3 SV=1 CANONICAL=A0A9J7FUD2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MPKGGCSKTPQQEDFSLSNDMVEKQTGKKDKDKVSLTKTPKLDRSDGGKEVRERATKRKLPFTVGANGEQKDSDTEKQGPERKRIKKEPVARKSGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQKTVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYSKNNALAPKKAAHRILSDTSDEEDVSVAMGAGEKLRLSAHTMLPSSKARESSSSRQQKEKNKLKKKRKKETKGKEVRFGKRNDKFCSSGSESESSESDEDDGDSVGSSSCLKGSPLVLKDPSLFSSLSASSTSSHGSASAQKHSSGHSDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESDCSSEGSSVESLKPTRRKQEHRKRGGLQSMPPEKRSTFHPCTDGAVSKLDKEGKVVKKHKTKHKHKNKEKGQSSVSQELKLKSFTYEYEDSKQKSDKAILLDNDISTENKLKVLKHDRDHFKKEDKLGKIKSEDKEWLFKDEKALKRIKDMSKEINRSFREEKDRPSKVEREKSTKEKSPKEEKLRLYKEERKKRSKDRPSKLEKKNDMKELSKEKDKSFKEDKEKLKKEKLYREDATFDEYCNKSQFLEHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDSPVTDYRDIKSDSVAKLILETVKDDSKEKKRDNRTREKRDFRDSFFRKKDRDYLDKNSEKRRDQTEKHKSIPSYLSEKDKKRRESADVVRDRRDTLEGSRERRDGRIRSEEVHREDLKECGCESTFKDKSDCDFTKNLEPWERPHAAREKERKDVLEKERKEKGRAEKYKDKSSERDRSEKSILEKCQKDKEFEKCFKEKKDGKEKHKDIHSKDRKASLDQMREKKEKMFPSIISEDFSEKKDDKKGKEKSWYIADIFTDESEDEKDDYVTSSFKVGEASDTQRVDSLQDKEDGREHPSDRHRKSSSDRQHTEKPRDKEPKEKKKDRGVAEGGKDKKEKIFEKHKEKKEKECAEKYKDRKDRASIDSAQEKKNKQKVPEKVEKKHFAEDKAKSKHKEKPEKEHSRERKSSRGPEVEKSLLEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVSFSEPPPEDKTRENTCLSEKLREKERHRHSSSSSKKSHERERAKKEKAEKKEKSEDYKDNSSGIRKDSSQYEKDFLDTEAYGVSYTTKADIEEELDKAIELFSSEKKDRNDSEREPAKKIEKELKPYGSSTISILKEKKKREKHREKWRDEKEKHRDKHVDGFLRHHKDEPKPTAKDKDNPPNSFKEKSRDESLKLSETKLKEKFKENTEREKGDLVKMSNGNDKLLPSRDSSKKDIRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEKKPTDDGRKKSLDLPSKKALGLDPPFKDKKLKESATTLPTGESKPHTGPGTESKDWLAGQPLKEVLSASPRTEQGRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTTSTSACSPPFFDRFSVASSVVSENPGQTPTRPVSTNLYRSISVDIRRTPEEEFSVGDKLFRQQSVPAASFDSPVQHLLEEKTPLPPVPAEKFACLSPGYYSPDYGIPSPKVDTLHCPPTAVVNATPPPDSVFSSLPAKSSPSPRGELVTPAIEGTLPPDLGLPLDATEDQQATAAILPPEPSYLEPLDEGPFNTVITEEPVEWAHTTAEQALSSTLIASASENPVSWPVGSELLLKSPQRFAESPKHFCPGESLHSTTPGPFSAAEPTYPVSPVSYPLPAPESGLEEVKDGGTGAIPVAISAAEGAAPYAAPTRLESYFNNCKSIPDAPLDTAPETTCVTTVAQVEALGPLESSFLDSNHSMSALSQVEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDASDVEAEAVEGSPVPPVESSPGPTGVLSSGEVTASATEEQPAPPPEEASPQCSTEPEPSEEPKLDVVLEATVETEVPADDSAPEASVSNLVSAPSPPEQHPLGGGDDETEVEDPSAAPCCASDGPTTDGLTQAHNNAEATCVVAAAEGPPGNIQPEATDTESKPSAEVPKAPKVEEVPQRMTRNRAQMLASQSKQNITPTEKDPMPAPTSRAKGRASEEEDAQAQHPRKRRFQRSSQQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2648, "header": "tr|A0A9J7FS28-1|A0A9J7FS28_CRIGR Isoform 1 of Ankyrin repeat domain-containing protein 11 OS=Cricetulus griseus OX=10029 GN=Ankrd11 PE=4 SV=1 CANONICAL=A0A9J7FS28-1" }, "isoforms": [ { "isoform_ac": "A0A061IFR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS28/entry#A0A061IFR6-1", "sequence": { "sequence": "MESRKTRTQMPPAQSMLWYCKAGTVLEAPWHEMEVPRSKKKEKQGPERKRIKKEPVARKSGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQKTVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYSKNNALAPKKAAHRILSDTSDEEDVSVAMGAGEKLRLSAHTMLPSSKARESSSSRQQKEKNKLKKKRKKETKGKEVRFGKRNDKFCSSGSESESSESDEDDGDSVGSSSCLKGSPLVLKDPSLFSSLSASSTSSHGSASAQKHSSGHSDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESDCSSEGSSVESLKPTRRKQEHRKRGGLQSMPPEKRSTFHPCTDGAVSKLDKEGKVVKKHKTKHKHKNKEKGQSSVSQELKLKSFTYEYEDSKQKSDKAILLDNDISTENKLKVLKHDRDHFKKEDKLGKIKSEDKEWLFKDEKALKRIKDMSKEINRSFREEKDRPSKVEREKSTKEKSPKEEKLRLYKEERKKRSKDRPSKLEKKNDMKELSKEKDKSFKEDKEKLKKEKLYREDATFDEYCNKSQFLEHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDSPVTDYRDIKSDSVAKLILETVKDDSKEKKRDNRTREKRDFRDSFFRKKDRDYLDKNSEKRRDQTEKHKSIPSYLSEKDKKRRESADVVRDRRDTLEGSRERRDGRIRSEEVHREDLKECGCESTFKDKSDCDFTKNLEPWERPHAAREKERKDVLEKERKEKGRAEKYKDKSSERDRSEKSILEKCQKDKEFEKCFKEKKDGKEKHKDIHSKDRKASLDQMREKKEKMFPSIISEDFSEKKDDKKGKEKSWYIADIFTDESEDEKDDYVTSSFKVGEASDTQRVDSLQDKEDGREHPSDRHRKSSSDRQHTEKPRDKEPKEKKKDRGVAEGGKDKKEKIFEKHKEKKEKECAEKYKDRKDRASIDSAQEKKNKQKVPEKVEKKHFAEDKAKSKHKEKPEKEHSRERKSSRGPEVEKSLLEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVSFSEPPPEDKTRENTCLSEKLREKERHRHSSSSSKKSHERERAKKEKAEKKEKSEDYKDNSSGIRKDSSQYEKDFLDTEAYGVSYTTKADIEEELDKAIELFSSEKKDRNDSEREPAKKIEKELKPYGSSTISILKEKKKREKHREKWRDEKEKHRDKHVDGFLRHHKDEPKPTAKDKDNPPNSFKEKSRDESLKLSETKLKEKFKENTEREKGDLVKMSNGNDKLLPSRDSSKKDIRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEKKPTDDGRKKSLDLPSKKALGLDPPFKDKKLKESATTLPTGESKPHTGPGTESKDWLAGQPLKEVLSASPRTEQGRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTTSTSACSPPFFDRFSVASSVVSENPGQTPTRPVSTNLYRSISVDIRRTPEEEFSVGDKLFRQQSVPAASFDSPVQHLLEEKTPLPPVPAEKFACLSPGYYSPDYGIPSPKVDTLHCPPTAVVNATPPPDSVFSSLPAKSSPSPRGELVTPAIEGTLPPDLGLPLDATEDQQATAAILPPEPSYLEPLDEGPFNTVITEEPVEWAHTTAEQALSSTLIASASENPVSWPVGSELLLKSPQRFAESPKHFCPGESLHSTTPGPFSAAEPTYPVSPVSYPLPAPESGLEEVKDGGTGAIPVAISAAEGAAPYAAPTRLESYFNNCKSIPDAPLDTAPETTCVTTVAQVEALGPLESSFLDSNHSMSALSQVEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDASDVEAEAVEGSPVPPVESSPGPTGVLSSGEVTASATEEQPAPPPEEASPQCSTEPEPSEEPKLDVVLEATVETEVPADDSAPEASVSNLVSAPSPPEQHPLGGGDDETEVEDPSAAPCCASDGPTTDGLTQAHNNAEATCVVAAAEGPPGNIQPEATDTESKPSAEVPKAPKVEEVPQRMTRNRAQMLASQSKQNITPTEKDPMPAPTSRAKGRASEEEDAQAQHPRKRRFQRSSQQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2615, "header": "tr|A0A061IFR6-1|A0A061IFR6_CRIGR Computationally mapped isoform of Ankyrin repeat domain-containing protein 11 OS=Cricetulus griseus OX=10029 GN=Ankrd11 PE=4 SV=1 CANONICAL=A0A9J7FS28-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FS28-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS28/entry#A0A9J7FS28-1", "sequence": { "sequence": "MPKGGCSKTPQQEDFSLSNDMVEKQTGKKDKDKVSLTKTPKLDRSDGGKEVRERATKRKLPFTVGANGEQKDSDTEKQGPERKRIKKEPVARKSGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKLKAKNPEPQKTVTPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYSKNNALAPKKAAHRILSDTSDEEDVSVAMGAGEKLRLSAHTMLPSSKARESSSSRQQKEKNKLKKKRKKETKGKEVRFGKRNDKFCSSGSESESSESDEDDGDSVGSSSCLKGSPLVLKDPSLFSSLSASSTSSHGSASAQKHSSGHSDQHTKHWRTDNWKAISSPAWSEVSSLSDSSRTGLTSESDCSSEGSSVESLKPTRRKQEHRKRGGLQSMPPEKRSTFHPCTDGAVSKLDKEGKVVKKHKTKHKHKNKEKGQSSVSQELKLKSFTYEYEDSKQKSDKAILLDNDISTENKLKVLKHDRDHFKKEDKLGKIKSEDKEWLFKDEKALKRIKDMSKEINRSFREEKDRPSKVEREKSTKEKSPKEEKLRLYKEERKKRSKDRPSKLEKKNDMKELSKEKDKSFKEDKEKLKKEKLYREDATFDEYCNKSQFLEHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDSPVTDYRDIKSDSVAKLILETVKDDSKEKKRDNRTREKRDFRDSFFRKKDRDYLDKNSEKRRDQTEKHKSIPSYLSEKDKKRRESADVVRDRRDTLEGSRERRDGRIRSEEVHREDLKECGCESTFKDKSDCDFTKNLEPWERPHAAREKERKDVLEKERKEKGRAEKYKDKSSERDRSEKSILEKCQKDKEFEKCFKEKKDGKEKHKDIHSKDRKASLDQMREKKEKMFPSIISEDFSEKKDDKKGKEKSWYIADIFTDESEDEKDDYVTSSFKVGEASDTQRVDSLQDKEDGREHPSDRHRKSSSDRQHTEKPRDKEPKEKKKDRGVAEGGKDKKEKIFEKHKEKKEKECAEKYKDRKDRASIDSAQEKKNKQKVPEKVEKKHFAEDKAKSKHKEKPEKEHSRERKSSRGPEVEKSLLEKLEEEALHDYREDSNDKISEVSSDSFADHGQEPSLSTLLEVSFSEPPPEDKTRENTCLSEKLREKERHRHSSSSSKKSHERERAKKEKAEKKEKSEDYKDNSSGIRKDSSQYEKDFLDTEAYGVSYTTKADIEEELDKAIELFSSEKKDRNDSEREPAKKIEKELKPYGSSTISILKEKKKREKHREKWRDEKEKHRDKHVDGFLRHHKDEPKPTAKDKDNPPNSFKEKSRDESLKLSETKLKEKFKENTEREKGDLVKMSNGNDKLLPSRDSSKKDIRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKMRHRSGDPKLKEKKPTDDGRKKSLDLPSKKALGLDPPFKDKKLKESATTLPTGESKPHTGPGTESKDWLAGQPLKEVLSASPRTEQGRPTGVPTPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTTSTSACSPPFFDRFSVASSVVSENPGQTPTRPVSTNLYRSISVDIRRTPEEEFSVGDKLFRQQSVPAASFDSPVQHLLEEKTPLPPVPAEKFACLSPGYYSPDYGIPSPKVDTLHCPPTAVVNATPPPDSVFSSLPAKSSPSPRGELVTPAIEGTLPPDLGLPLDATEDQQATAAILPPEPSYLEPLDEGPFNTVITEEPVEWAHTTAEQALSSTLIASASENPVSWPVGSELLLKSPQRFAESPKHFCPGESLHSTTPGPFSAAEPTYPVSPVSYPLPAPESGLEEVKDGGTGAIPVAISAAEGAAPYAAPTRLESYFNNCKSIPDAPLDTAPETTCVTTVAQVEALGPLESSFLDSNHSMSALSQVEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDASDVEAEAVEGSPVPPVESSPGPTGVLSSGEVTASATEEQPAPPPEEASPQCSTEPEPSEEPKLDVVLEATVETEVPADDSAPEASVSNLVSAPSPPEQHPLGGGDDETEVEDPSAAPCCASDGPTTDGLTQAHNNAEATCVVAAAEGPPGNIQPEATDTESKPSAEVPKAPKVEEVPQRMTRNRAQMLASQSKQNITPTEKDPMPAPTSRAKGRASEEEDAQAQHPRKRRFQRSSQQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRSNPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFKQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKAQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA", "length": 2648, "header": "tr|A0A9J7FS28-1|A0A9J7FS28_CRIGR Isoform 1 of Ankyrin repeat domain-containing protein 11 OS=Cricetulus griseus OX=10029 GN=Ankrd11 PE=4 SV=1 CANONICAL=A0A9J7FS28-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2166, "start_aa": "Thr", "end_pos": 2166, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2166", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS28" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS28" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "head morphogenesis", "id": "GO:0060323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060323", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS28" } ], "pmid": "" }, { "name": "face development", "id": "GO:0060324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060324", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS28" } ], "pmid": "" }, { "name": "skeletal system morphogenesis", "id": "GO:0048705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048705", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS28" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS28" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1382, "end_pos": 1384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1432, "end_pos": 1434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1865, "end_pos": 1867, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2101, "end_pos": 2103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2338, "end_pos": 2340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2386, "end_pos": 2388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2560, "end_pos": 2562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" }, { "start_pos": 893, "end_pos": 895, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 2166 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1382, "end_pos": 1384 }, { "start_pos": 1432, "end_pos": 1434 }, { "start_pos": 1865, "end_pos": 1867 }, { "start_pos": 2101, "end_pos": 2103 }, { "start_pos": 2338, "end_pos": 2340 }, { "start_pos": 2386, "end_pos": 2388 }, { "start_pos": 2560, "end_pos": 2562 }, { "start_pos": 316, "end_pos": 318 }, { "start_pos": 732, "end_pos": 734 }, { "start_pos": 820, "end_pos": 822 }, { "start_pos": 893, "end_pos": 895 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FS37-1", "uniprot_ac": "A0A9J7FS37", "uniprot_id": "A0A9J7FS37_CRIGR", "mass": { "chemical_mass": 277761.0, "monoisotopic_mass": 277761.0 }, "refseq": { "ac": "XP_007641028", "name": "protein dopey-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641028" }, "gene_names": [ { "name": "Dop1a", "type": "recommended", "evidence": [ { "id": "A0A9J7FS37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" } ] }, { "name": "Dop1a", "type": "synonym", "evidence": [ { "id": "XP_007641028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641028" } ] } ], "protein_names": [ { "name": "Protein dopey-1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7FS37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37/entry#names_and_taxonomy" } ] }, { "name": "protein dopey-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007641028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641028" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007641028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641028" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dop1a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37", "locus": {} } ], "crossref": [ { "id": "100763056", "url": "https://www.ncbi.nlm.nih.gov/gene/100763056", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763056", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763056", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N8A3", "url": "https://www.orthodb.org/?gene=A0A8C2N8A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FS37", "url": "https://www.orthodb.org/?gene=A0A9J7FS37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14042", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14042", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14042:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14042:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04118", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04118", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24601", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24601", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26706", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007641028", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641028", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N8A3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N8A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N8A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N8A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FS37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FS37-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPALLSLYEIYYLPLGKTLKPGLQGLLTGILPGLEEGSEYYERTNTLLEKVAAAVEQSAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMVRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAIIGPRSTRHSNPEEHATYYFTTFSKELLVQAMVGILQVNGFGEESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCRRTLHARLQVGPGDSSDSSELQLTNFCLLVDFLLDIVSLETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQPPLLSAGTGGSVQFPSGHNSTVKEWEDKKVSSVSMENPTEVFEDGENPPSSRSSESGFTEFIQYQADRTDDLDRELNGQGTATIPIGSTSSETETASTVGSEETVIHAPSTFTQSAAARSGKAAQKTAMQCCLEYVQQFLSRLINLYIIHRDSLSQPLAADHQGDLRRLQRETSKWDRDSQGDAKERNIHTPKNSKEYISAFLAACQLFLECSSFPVYIAEGNHTSELHSEKLDTDCEHAHPPQWLQTLMSACSQASDFSVQSVAVSLVMDLVGLTQSVAMVTGENINSMESAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQMGDGTPQHHQKSVELFYQLHNLVPSSSICEDVISQQLTHKDKKIRMEAHAKFAVLWHLTRDLHINKSSFARSFDRSLFIMLDSLNSLDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEESDKHFMQNFTCNNVSQAHLIASKGNGEKPLTMDEIENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQSSDSGCSQSSAGDNFSYEVDPENVTAHEDSLMAKASSPDDDVQQVVFDLICKVVSGLEAESASVTSELEIESLPPKSSDLDPSLEAMKSEDQAPQHSQHALLGEDSQRFLSVSAEEGCECLANGISRNSSSPCISGTAQTFNDSSVSTETKSRQRSHSSIQFSFKEKLSEKISEKETIVKESGKQPGAKPKVKLARKKDEDKKKVASEKLKQTNVFFSDGLDLENWYSCGEGEISEIESDMGSPGSRKSPHFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKTNPVAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHNFRSSMYIEILISLCLYYMRSHYPTHVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSVQKWHSEKIAGKNMVAVEEGFSEDSLINFSEDEFDNGSTLQSQLLRVLQRLIVLEHRVMTIPEENEAGFDFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGKVLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWIASVIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLFEARGGILSILHMIMSSVTLLWSILHQADASEKMVVAASASVTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNERRQNKNPSRTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDKKHLSLEVCMLQFFYAYIQRIPVPNLVDSWTSLLVLLKDSIQLSLPAPGQFLILGVLNEFIMKNPSLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVNHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLRLPQVPTLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQRWLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRTKDEEDFKILEGMEMAKHQKNPEEDSSGRTLGWEPGHLLLTLCTMRSMEQLLPFFNILSQVFNSKVTSRCGGHSGSPVLYSNSFPNKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT", "length": 2469, "header": "tr|A0A9J7FS37-1|A0A9J7FS37_CRIGR Isoform 1 of Protein dopey-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Dop1a PE=3 SV=1 CANONICAL=A0A9J7FS37-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N8A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37/entry#A0A8C2N8A3-1", "sequence": { "sequence": "MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPALLSLYEIYYLPLGKTLKPGLQGLLTGILPGLEEGSEYYERTNTLLEKVAAAVEQSAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMVRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAIIGPRSTRHSNPEEHATYYFTTFSKELLVQAMVGILQVNGFGEESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCRRTLHARLQVGPGDSSDSSELQLTNFCLLVDFLLDIVSLETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQPPLLSAGTGGSVQFPSGHNSTVKEWEDKKVSSVSMENPTEVFEDGENPPSSRSSESGFTEFIQYQADRTDDLDRELNGQGTATIPIGSTSSETETASTVGSEETVIHAPSTFTQSAAARSGKAAQKTAMQCCLEYVQQFLSRLINLYIIHRDSLSQPLAADHQGDLRRLQRETSKWDRDSQGDAKERNIHTPKNSKEYISAFLAACQLFLECSSFPVYIAEGNHTSELHSEKLDTDCEHAHPPQWLQTLMSACSQASDFSVQSVAVSLVMDLVGLTQSVAMVTGENINSMESAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQMGDGTPQHHQKSVELFYQLHNLVPSSSICEDVISQQLTHKDKKIRMEAHAKFAVLWHLTRDLHINKSSFARSFDRSLFIMLDSLNSLDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEESDKHFMQNFTCNNVSQAHLIASKGNGEKPLTMDEIENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQSSDSGCSQSSAGDNFSYEVDPENVTAHEDSLMAKASSPDDDVQQVVFDLICKVVSGLEAESASVTSELEIESLPPKSSDLDPSLEAMKSEDQAPQHSQHALLGEDSQRFLSVSAEEGCECLANGISRNSSSPCISGTAQTFNDSSVSTETKSRQRSHSSIQFSFKEKLSEKISEKETIVKESGKQPGAKPKVKLARKKDEDKKKVASEKLKQTNVFFSDGLDLENWYSCGEGEISEIESDMGSPGSRKSPHFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKTNPVAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHNFRSSMYIEILISLCLYYMRSHYPTHVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSVQKWHSEKIAGKNMVAVEEGFSEDSLINFSEDEFDNGSTLQSQLLRVLQRLIVLEHRVMTIPEENEAGFDFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGKVLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWIASVIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLFEARGGILSILHMIMSSVTLLWSILHQADASEKMVVAASASVTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNERRQNKNPSRTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDKKHLSLEVCMLQFFYAYIQRIPVPNLVDSWTSLLVLLKDSIQLSLPAPGQFLILGVLNEFIMKNPSLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVNHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLRLPQVPTLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQRWLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRTKKNPEEDSSGRTLGWEPGHLLLTLCTMRSMEQLLPFFNILSQVFNSKVTSRCGGHSGSPVLYSNSFPNKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT", "length": 2452, "header": "tr|A0A8C2N8A3-1|A0A8C2N8A3_CRIGR Computationally mapped isoform of Protein dopey-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dop1a PE=3 SV=1 CANONICAL=A0A9J7FS37-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FS37-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37/entry#A0A9J7FS37-1", "sequence": { "sequence": "MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPALLSLYEIYYLPLGKTLKPGLQGLLTGILPGLEEGSEYYERTNTLLEKVAAAVEQSAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMVRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAIIGPRSTRHSNPEEHATYYFTTFSKELLVQAMVGILQVNGFGEESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCRRTLHARLQVGPGDSSDSSELQLTNFCLLVDFLLDIVSLETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQPPLLSAGTGGSVQFPSGHNSTVKEWEDKKVSSVSMENPTEVFEDGENPPSSRSSESGFTEFIQYQADRTDDLDRELNGQGTATIPIGSTSSETETASTVGSEETVIHAPSTFTQSAAARSGKAAQKTAMQCCLEYVQQFLSRLINLYIIHRDSLSQPLAADHQGDLRRLQRETSKWDRDSQGDAKERNIHTPKNSKEYISAFLAACQLFLECSSFPVYIAEGNHTSELHSEKLDTDCEHAHPPQWLQTLMSACSQASDFSVQSVAVSLVMDLVGLTQSVAMVTGENINSMESAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQMGDGTPQHHQKSVELFYQLHNLVPSSSICEDVISQQLTHKDKKIRMEAHAKFAVLWHLTRDLHINKSSFARSFDRSLFIMLDSLNSLDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEESDKHFMQNFTCNNVSQAHLIASKGNGEKPLTMDEIENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQSSDSGCSQSSAGDNFSYEVDPENVTAHEDSLMAKASSPDDDVQQVVFDLICKVVSGLEAESASVTSELEIESLPPKSSDLDPSLEAMKSEDQAPQHSQHALLGEDSQRFLSVSAEEGCECLANGISRNSSSPCISGTAQTFNDSSVSTETKSRQRSHSSIQFSFKEKLSEKISEKETIVKESGKQPGAKPKVKLARKKDEDKKKVASEKLKQTNVFFSDGLDLENWYSCGEGEISEIESDMGSPGSRKSPHFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKTNPVAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHNFRSSMYIEILISLCLYYMRSHYPTHVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSVQKWHSEKIAGKNMVAVEEGFSEDSLINFSEDEFDNGSTLQSQLLRVLQRLIVLEHRVMTIPEENEAGFDFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGKVLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWIASVIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLFEARGGILSILHMIMSSVTLLWSILHQADASEKMVVAASASVTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNERRQNKNPSRTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDKKHLSLEVCMLQFFYAYIQRIPVPNLVDSWTSLLVLLKDSIQLSLPAPGQFLILGVLNEFIMKNPSLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVNHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLRLPQVPTLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQRWLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRTKDEEDFKILEGMEMAKHQKNPEEDSSGRTLGWEPGHLLLTLCTMRSMEQLLPFFNILSQVFNSKVTSRCGGHSGSPVLYSNSFPNKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT", "length": 2469, "header": "tr|A0A9J7FS37-1|A0A9J7FS37_CRIGR Isoform 1 of Protein dopey-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Dop1a PE=3 SV=1 CANONICAL=A0A9J7FS37-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37/entry#A0A9J7GVK0-1", "sequence": { "sequence": "MSVKPALLSLYEIYYLPLGKTLKPGLQGLLTGILPGLEEGSEYYERTNTLLEKVAAAVEQSAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMVRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAIIGPRSTRHSNPEEHATYYFTTFSKELLVQAMVGILQVNGFGEESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCRRTLHARLQVGPGDSSDSSELQLTNFCLLVDFLLDIVSLETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQPPLLSAGTGGSVQFPSGHNSTVKEWEDKKVSSVSMENPTEVFEDGENPPSSRSSESGFTEFIQYQADRTDDLDRELNGQGTATIPIGSTSSETETASTVGSEETVIHAPSTFTQSAAARSGKAAQKTAMQCCLEYVQQFLSRLINLYIIHRDSLSQPLAADHQGDLRRLQRETSKWDRDSQGDAKERNIHTPKNSKEYISAFLAACQLFLECSSFPVYIAEGNHTSELHSEKLDTDCEHAHPPQWLQTLMSACSQASDFSVQSVAVSLVMDLVGLTQSVAMVTGENINSMESAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQMGDGTPQHHQKSVELFYQLHNLVPSSSICEDVISQQLTHKDKKIRMEAHAKFAVLWHLTRDLHINKSSFARSFDRSLFIMLDSLNSLDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEESDKHFMQNFTCNNVSQAHLIASKGNGEKPLTMDEIENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQSSDSGCSQSSAGDNFSYEVDPENVTAHEDSLMAKASSPDDDVQQVVFDLICKVVSGLEAESASVTSELEIESLPPKSSDLDPSLEAMKSEDQAPQHSQHALLGEDSQRFLSVSAEEGCECLANGISRNSSSPCISGTAQTFNDSSVSTETKSRQRSHSSIQFSFKEKLSEKISEKETIVKESGKQPGAKPKVKLARKKDEDKKKVASEKLKQTNVFFSDGLDLENWYSCGEGEISEIESDMGSPGSRKSPHFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKTNPVAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHNFRSSMYIEILISLCLYYMRSHYPTHVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSVQKWHSEKIAGKNMVAVEEGFSEDSLINFSEDEFDNGSTLQSQLLRVLQRLIVLEHRVMTIPEENEAGFDFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGKVLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWIASVIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLFEARGGILSILHMIMSSVTLLWSILHQADASEKMVVAASASVTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNERRQNKNPSRTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDKKHLSLEVCMLQFFYAYIQRIPVPNLVDSWTSLLVLLKDSIQLSLPAPGQFLILGVLNEFIMKNPSLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVNHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLRLPQVPTLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQRWLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRTKDEEDFKILEGMEMAKHQKNPEEDSSGRTLGWEPGHLLLTLCTMRSMEQLLPFFNILSQVFNSKVTSRCGGHSGSPVLYSNSFPNKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT", "length": 2351, "header": "tr|A0A9J7GVK0-1|A0A9J7GVK0_CRIGR Computationally mapped isoform of Protein dopey-1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Dop1a PE=3 SV=1 CANONICAL=A0A9J7FS37-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763056", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763056", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FS37", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1026, "end_pos": 1028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1031, "end_pos": 1033, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1055, "end_pos": 1057, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1109, "end_pos": 1111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1118, "end_pos": 1120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1223, "end_pos": 1225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1553, "end_pos": 1555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1561, "end_pos": 1563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2014, "end_pos": 2016, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2065, "end_pos": 2067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 757, "end_pos": 759, "annotation": "n_glycosylation_sequon" }, { "start_pos": 935, "end_pos": 937, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FS37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" }, { "id": "PF04118", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 295, "start_aa": "Asp", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FS37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" }, { "id": "PF24598", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24598" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 1891, "end_pos": 2408, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FS37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" }, { "id": "PF24601", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24601" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1-like TPR", "eco_id": "ECO_0000259", "start_pos": 1350, "end_pos": 1724, "start_aa": "His", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FS37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS37" }, { "id": "PF24597", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24597" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1-like middle TPR", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 535, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1026, "end_pos": 1028 }, { "start_pos": 1031, "end_pos": 1033 }, { "start_pos": 1055, "end_pos": 1057 }, { "start_pos": 1109, "end_pos": 1111 }, { "start_pos": 1118, "end_pos": 1120 }, { "start_pos": 1223, "end_pos": 1225 }, { "start_pos": 1237, "end_pos": 1239 }, { "start_pos": 1553, "end_pos": 1555 }, { "start_pos": 1561, "end_pos": 1563 }, { "start_pos": 2014, "end_pos": 2016 }, { "start_pos": 2065, "end_pos": 2067 }, { "start_pos": 553, "end_pos": 555 }, { 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267060" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSG3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tln2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSG3", "locus": {} } ], "crossref": [ { "id": "cd10569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12150", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12150", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17172", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17172", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17174", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17174", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770331", "url": "https://www.ncbi.nlm.nih.gov/gene/100770331", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770331", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770331", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FSG3", "url": "https://www.orthodb.org/?gene=A0A9J7FSG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19981:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19981:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08913", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08913", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09379", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09379", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16511", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16511", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21692", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21692", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21865", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21865", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21896", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21896", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267060", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FSG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLW1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDPLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGENETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATGDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPSAQQQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGVAASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAPNAKNLLAAAARAVTESINQLIMLCTQQAPGQKECDNALRELETVKGMLENPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVKYSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLALQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAENGETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDPETQVVLINAIKDVAKALSDLIGATKGAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTVFQSKDIPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTACKQASFYPDVSEEVRTRALRYGTECTLGYLDLLEHVLVILQKPTPELKHQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLPTELREDEG", "length": 2544, "header": "tr|A0A9J7FSG3-1|A0A9J7FSG3_CRIGR Isoform 1 of Talin-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tln2 PE=4 SV=1 CANONICAL=A0A9J7FSG3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FSG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSG3/entry#A0A9J7FSG3-1", "sequence": { "sequence": "MKMVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDPLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGENETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATGDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPSAQQQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGVAASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAPNAKNLLAAAARAVTESINQLIMLCTQQAPGQKECDNALRELETVKGMLENPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVKYSKAIAVTAQEMMTKSVTNPEELGGLASQMTSDYGHLALQGQMAAATAEPEEIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAENGETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDPETQVVLINAIKDVAKALSDLIGATKGAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTVFQSKDIPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTACKQASFYPDVSEEVRTRALRYGTECTLGYLDLLEHVLVILQKPTPELKHQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLPTELREDEG", "length": 2544, "header": "tr|A0A9J7FSG3-1|A0A9J7FSG3_CRIGR Isoform 1 of Talin-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tln2 PE=4 SV=1 CANONICAL=A0A9J7FSG3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSG3/entry#A0A9J7JLW1-1", "sequence": { "sequence": "MKMVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRKGIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSRIGITNYEEYSLIQETIEEKKEEGTGTLKKDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFLPKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQAQDDLSELDPLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTASVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMDDDVGSGEDLLRAARTLAGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQIGENETDERFQDVLMSLAKAVANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQEQLIEAGKLVDRSVENCVRACQAATGDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEPIGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDAEAEIDMENSKKLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVATNAAAQNAIKKKIVNRLEVAAKQAAAAATQTIAASQNAAVSNKNPSAQQQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVPTVSDQAAAMQLSQCAKNLATSLAELRTASQKAHEACGPMEIDSALNTVQTLKNELQDAKMAAAESQLKPLPGETLEKCAQDLGSTSKGVGSSMAQLLTCAAQGNEHYTGVAARETAQALKTLAQAARGVAASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQALIAPGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGESSKKLLVDSLPPSTKPFQEAQSELNQAAADLNQSAGEVVHATRGQSGELAAASGKFSDDFDEFLDAGIEMAGQAQTKEDQMQVIGNLKNISMASSKLLLAAKSLSVDPGAPNAKNLLAAAARAVTESINQLIMLCTQQAPGQKECDNALRELETVKGMLENPNEPVSDLSYFDCIESVMENSKVLGESMAGISQNAKTGDLPAFGECVGIASKALCGLTEAAAQAAYLVGISDPNSQAGHQGLVDPIQFARANQAIQMACQNLVDPGSSPSQVLSAATIVAKHTSALCNACRIASSKTANPVAKRHFVQSAKEVANSTANLVKTIKALDGDFSEDNRNKCRIATTPLIEAVENLTAFASNPEFVSIPAQISSEGSQAQEPILVSAKTMLESSSYLIRTARSLAINPKDPPTWSVLAGHSHTVSDSIKSLITSIRDKAPGQRECDYSIDGINRCIRDIEQASLAAVSQSLATRDDISVEALQEQLTSVVQEIGHLIDPIATAARGEAAQLGHKVTQLASYFEPLILAAVGVASKMLDHQQQMTVLDQTKTLAESALQMLYAAKEGGGNPKAQHTHDAITEAAQLMKEAVDDIMVTLNEAASEVGLVGGMVDAIAEAMSKLDEGTPPEPKGTFVDYQTTVVKYSKAIAVTAQEMIGFQIRTRVQDLGHGCIFLVQKAGALQVCPTDSYTKRELIECARSVTEKVSLVLSALQAGNKGTQACITAATAVSGIIADLDTTIMFATAGTLNAENGETFADHRENILKTAKALVEDTKLLVSGAASTPDKLAQAAQSSAATITQLAEVVKLGAASLGSNDPETQVVLINAIKDVAKALSDLIGATKGAASKPADDPSMYQLKGAAKVMVTNVTSLLKTVKAVEDEATRGTRALEATIEYIKQELTVFQSKDIPEKTSSPEESIRMTKGITMATAKAVAAGNSCRQEDVIATANLSRKAVSDMLTACKQASFYPDVSEEVRTRALRYGTECTLGYLDLLEHVLVILQKPTPELKHQLAAFSKRVAGAVTELIQAAEAMKGTEWVDPEDPTVIAETELLGAAASIEAAAKKLEQLKPRAKPKQADETLDFEEQILEAAKSIAAATSALVKSASAAQRELVAQGKVGSIPANAADDGQWSQGLISAARMVAAATSSLCEAANASVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRLQAAGNAVKRASDNLVRAAQKAAFGKADDDDVVVKTKFVGGIAQIIAAQEEMLKKERELEEARKKLAQIRQQQYKFLPTELREDEG", "length": 2504, "header": "tr|A0A9J7JLW1-1|A0A9J7JLW1_CRIGR Computationally mapped isoform of Talin-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tln2 PE=4 SV=1 CANONICAL=A0A9J7FSG3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1945, "start_aa": "Thr", "end_pos": 1945, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1945", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSJ8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSJ8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751376", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751376", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSJ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "methionyl-tRNA formyltransferase activity", "id": "GO:0004479", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004479", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24380", "name": "", "equation": "L-methionyl-tRNA(fMet) + (6R)-10-formyltetrahydrofolate = N-formyl-L-methionyl-tRNA(fMet) + (6S)-5,6,7,8-tetrahydrofolate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7FSJ8-1" ], "evidence": [ { "id": "24380", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24380" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7FSJ8", "gene_name": "Mtfmt", "activity": [ { "ec_number": "2.1.2.9", "activity": "L-methionyl-tRNA(fMet) + (6R)-10-formyltetrahydrofolate = N-formyl-L-methionyl-tRNA(fMet) + (6S)-5,6,7,8-tetrahydrofolate + H(+).", "evidence": [ { "id": "A0A9J7FSJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSJ8" } ] }, { "ec_number": "2.1.2.9", "activity": "", "evidence": [ { "id": "A0A9J7FSJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSJ8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FSJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSJ8" }, { "id": "PF02911", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02911" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Formyl transferase C-terminal", "eco_id": "ECO_0000259", "start_pos": 253, "end_pos": 358, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FSJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSJ8" }, { "id": "PF00551", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00551" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Formyl transferase N-terminal", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 229, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.2.9", "ec_name": "L-methionyl-tRNA(fMet) + (6R)-10-formyltetrahydrofolate = N-formyl-L-methionyl-tRNA(fMet) + (6S)-5,6,7,8-tetrahydrofolate + H(+).", "evidence": [ { "id": "2.1.2.9", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.2.9" }, { "id": "2.1.2.9", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.2.9" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 244 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 301, "end_pos": 303 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FSK6-1", "uniprot_ac": "A0A9J7FSK6", "uniprot_id": "A0A9J7FSK6_CRIGR", "mass": { "chemical_mass": 117708.0, "monoisotopic_mass": 117708.0 }, "refseq": { "ac": "XP_027266784", "name": "sorting nexin-14 isoform X5", "summary": "", "url": 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Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266784" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Snx14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6", "locus": {} } ], "crossref": [ { "id": "A0A9J7FSK6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FSK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06877", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06877", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08722", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08722", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767333", "url": "https://www.ncbi.nlm.nih.gov/gene/100767333", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767333", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767333", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FSK6", "url": "https://www.orthodb.org/?gene=A0A9J7FSK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22775", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22775", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22775:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22775:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266784", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266784", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M3T9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M3T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M641", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M641", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M641-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M641-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWIRRRAVGVSSAAASEGGTSSAAWTEMGSWMRTFGGKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYLHVLMIFWSFVAGVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLENYQPWLDLKVPSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEYLQQAALEEYGPELHVALRSRRDELQYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKFNRGSLSLDDFRSTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGLAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGAHGDQKRPLDPLELELKTAVNCSSWIETKLRSSEEQQVLLTWKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSRPELTILSPTSENNKKLFNDLYKNNANRAETTERKQNQNYFMEVMTVDGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEATSMTSWM", "length": 1015, "header": "tr|A0A9J7FSK6-1|A0A9J7FSK6_CRIGR Isoform 1 of Sorting nexin-14 OS=Cricetulus griseus OX=10029 GN=Snx14 PE=3 SV=1 CANONICAL=A0A9J7FSK6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M3T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6/entry#A0A8C2M3T9-1", "sequence": { "sequence": "MWIRRRAVGVSSAAASEGGTSSAAWTEMGSWMRTFGGKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYLHVLMIFWSFVAGVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLENYQPWLDLKVPSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEYLQQAALEEYGPELHVALRSRRDELQYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKFNRGSLSLDDFRSTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGLAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSRPELTILSPTSENNKKLFNDLYKNNANRAETTERKQNQNYFMEVMTVDGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEATSMTSWM", "length": 973, "header": "tr|A0A8C2M3T9-1|A0A8C2M3T9_CRIGR Computationally mapped isoform of Sorting nexin-14 OS=Cricetulus griseus OX=10029 GN=Snx14 PE=3 SV=1 CANONICAL=A0A9J7FSK6-1" }, "locus": {} }, { "isoform_ac": "A0A8C2M641-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6/entry#A0A8C2M641-1", "sequence": { "sequence": "MWIRRRAVGVSSAAASEGGTSSAAWTEMGSWMRTFGGKLKQRLRLDVGREICRQYPLFCFLLLCLSAASLLLNRYLHVLMIFWSFVAGVVTFYCSLGPDSLLPNIFFTIKYKPKQLGLQELFPQGHSCAVCGKVKCKRHRPSLLLENYQPWLDLKVPSKVDASLSEVLELVLENFVYPWYRDVTDDESFVDELRITLRFFASVLVRRIHKVDIPSIITKKLLKAAMKHIEVIVKARQKVKNTEYLQQAALEEYGPELHVALRSRRDELQYLRKLTELLFPYILPPKATDCRSLTLLIREILSGSVFLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELKQIREQQDLLFRFMNFLKQEGAVHVLQFCLTVEEFNDRILRPELSNDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVLSLLENVFTPMFCHSDEYFRQLLRGAESPTRNSKFNRSTQKRGESFGISRIGSKIKGVFKSTTMEGAMLPNYGLAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAAWKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTEFHGTFPDAQLPSKRIIGPKNYEFLKSKREEFQEYLQKLLQHPELSNSQLLADFLSPNGGETQFLDKILPDVNLGKIIKSVPGKLMKEKGQHLEPFIMSFINSCESPKPKPSRPELTILSPTSENNKKLFNDLYKNNANRAETTERKQNQNYFMEVMTVDGVYDYLMYVGRVVFQVPDWLHHLLMGTRILFKNTLEMYTDYYLQCKLEQLFQEHRLVSLITLLRDAIFCENTEPRSLQDKQKGAKQTFEEMMNYIPDLIVKCIGEETKYESIRLLFDGLQQPVLNKQLTYVLLDIVIQELFPELNKVQKEATSMTSWM", "length": 964, "header": "tr|A0A8C2M641-1|A0A8C2M641_CRIGR Computationally mapped isoform of Sorting nexin-14 OS=Cricetulus griseus OX=10029 GN=Snx14 PE=3 SV=1 CANONICAL=A0A9J7FSK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FSK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6/entry#A0A9J7FSK6-1", "sequence": { "sequence": 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"A0A9J7FSK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6" } ], "pmid": "" }, { "name": "postsynaptic modulation of chemical synaptic transmission", "id": "GO:0099170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099170", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK6" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834901" }, "gene_names": [ { "name": "LOC100751386", "type": "recommended", "evidence": [ { "id": "A0A9J7FSK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ] }, { "name": "LOC100751386", "type": "synonym", "evidence": [ { "id": "XP_016834901", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834901" } ] } ], "protein_names": [ { "name": "Prolactin-3B1-like", "type": "synonym", "evidence": [ { "id": "A0A9J7FSK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9/entry#names_and_taxonomy" } ] }, { "name": "prolactin-3B1-like", "type": "synonym", "evidence": [ { "id": "XP_016834901", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834901" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614777.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016834901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834901" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100751386", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9", "locus": {} } ], "crossref": [ { "id": "A0A9J7FSK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FSK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10288", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10288", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751386", "url": "https://www.ncbi.nlm.nih.gov/gene/100751386", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751386", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751386", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FSK9", "url": "https://www.orthodb.org/?gene=A0A9J7FSK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11417", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11417", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11417:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11417:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016834901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834901", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLWNTPYVGSINLFFWQHVTSPPNPQMPTGSLYQPVVELSHYTHDLASKVFIEFNMKFGRRQNLMLSTCHTASIFTPENNEQVHQTKSEDLLKMTISVLQAWEVPPKHMVAAVAVLPDASDVIQSRTKELEERVLGLLEGLKTILNRVHPGAVENDYTFWSGWSDLQSSDGATRYFALSNLYHCFHKDSHKVDNYLKVLKC", "length": 202, "header": "tr|A0A9J7FSK9-1|A0A9J7FSK9_CRIGR Isoform 1 of Prolactin-3B1-like OS=Cricetulus griseus OX=10029 GN=LOC100751386 PE=3 SV=1 CANONICAL=A0A9J7FSK9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FSK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9/entry#A0A9J7FSK9-1", "sequence": { "sequence": "MLLWNTPYVGSINLFFWQHVTSPPNPQMPTGSLYQPVVELSHYTHDLASKVFIEFNMKFGRRQNLMLSTCHTASIFTPENNEQVHQTKSEDLLKMTISVLQAWEVPPKHMVAAVAVLPDASDVIQSRTKELEERVLGLLEGLKTILNRVHPGAVENDYTFWSGWSDLQSSDGATRYFALSNLYHCFHKDSHKVDNYLKVLKC", "length": 202, "header": "tr|A0A9J7FSK9-1|A0A9J7FSK9_CRIGR Isoform 1 of Prolactin-3B1-like OS=Cricetulus griseus OX=10029 GN=LOC100751386 PE=3 SV=1 CANONICAL=A0A9J7FSK9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751386", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751386", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "prolactin receptor binding", "id": "GO:0005148", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005148", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "pmid": "" }, { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "positive regulation of cell population proliferation", "id": "GO:0008284", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "pmid": "" }, { "name": "response to nutrient levels", "id": "GO:0031667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "pmid": "" }, { "name": "female pregnancy", "id": "GO:0007565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "pmid": "" }, { "name": "positive regulation of receptor signaling pathway via JAK-STAT", "id": "GO:0046427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046427", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "pmid": "" }, { "name": "mammary gland development", "id": "GO:0030879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030879", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "pmid": "" }, { "name": "positive regulation of lactation", "id": "GO:1903489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903489", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A9J7FSK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9#function" }, { "id": "A0A9J7FSK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSK9" }, { "id": "PIRSR601400-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601400-1" } ], "binding_site_uniprot": 194, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", 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"phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FSL4-1", "uniprot_ac": "A0A9J7FSL4", "uniprot_id": "A0A9J7FSL4_CRIGR", "mass": { "chemical_mass": 65693.0, "monoisotopic_mass": 65693.0 }, "refseq": { "ac": "XP_027267698", "name": "tripartite motif-containing protein 29 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267698" }, "gene_names": [ { "name": "Trim29", "type": "recommended", "evidence": [ { "id": "A0A9J7FSL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4" } ] }, { "name": "Trim29", "type": "synonym", "evidence": [ { "id": "XP_027267698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267698" } ] } ], "protein_names": [ { "name": "Tripartite motif-containing protein 29", "type": "recommended", "evidence": [ { "id": "A0A9J7FSL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4/entry#names_and_taxonomy" } ] }, { "name": "tripartite motif-containing protein 29 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027267698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267698" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267698" } ] }, { "annotation": "Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSL4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4#function" }, { "database": "UniProtKB", "id": "ARBA00056595", "url": "https://www.uniprot.org/uniprotkb/ARBA00056595#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSL4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Trim29", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4", "locus": {} } ], "crossref": [ { "id": "A0A9J7FSL4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FSL4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19840", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19840", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759376", "url": "https://www.ncbi.nlm.nih.gov/gene/100759376", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759376", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759376", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FSL4", "url": "https://www.orthodb.org/?gene=A0A9J7FSL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FSL4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGADASRSNGASPEARDTRSPSGPNGSLENGTKADSKDTKTTNGHSGEVTEGKTLGSALKSGEGKSALFSSNEWRRPIIQFVESVDDKGSNYFSMDSAEGRRSPYAGLQLGASKKPPVTFAEKGELRKSIFSEPRKPTVTIVEPGDIRRNSYPRADSGLLLRSKSGSEEVLCDSCIGNKQKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPLHGKTMELFCQTDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIVDALDERAKVLHEDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCKADLSRNFIERNHMENGGDHRYMNSYTSSYGNEWSTPDTMKRYSMYLTPKGGARTYQPSSPSRLSKETNQKNFSNLYGTKGNYTSRVWEYSSTVQNSEDLPTVPGNSSFSLKGYPSILRSQASKAQPQTWKSGKQTLLSHYRPFYVNKGSGIGSNEAP", "length": 586, "header": "tr|A0A9J7FSL4-1|A0A9J7FSL4_CRIGR Isoform 1 of Tripartite motif-containing protein 29 OS=Cricetulus griseus OX=10029 GN=Trim29 PE=4 SV=1 CANONICAL=A0A9J7FSL4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FSL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4/entry#A0A9J7FSL4-1", "sequence": { "sequence": "MEGADASRSNGASPEARDTRSPSGPNGSLENGTKADSKDTKTTNGHSGEVTEGKTLGSALKSGEGKSALFSSNEWRRPIIQFVESVDDKGSNYFSMDSAEGRRSPYAGLQLGASKKPPVTFAEKGELRKSIFSEPRKPTVTIVEPGDIRRNSYPRADSGLLLRSKSGSEEVLCDSCIGNKQKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKCPLHGKTMELFCQTDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEIEDEAEKWQKEKDRIKSFTTNEKAILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQVKVIVDALDERAKVLHEDKQTREQLHSISDSVLFLQEFGALMSNYSLPPPLPTYHVLLEGEGLGQSLGNFKDDLLNVCMRHVEKMCKADLSRNFIERNHMENGGDHRYMNSYTSSYGNEWSTPDTMKRYSMYLTPKGGARTYQPSSPSRLSKETNQKNFSNLYGTKGNYTSRVWEYSSTVQNSEDLPTVPGNSSFSLKGYPSILRSQASKAQPQTWKSGKQTLLSHYRPFYVNKGSGIGSNEAP", "length": 586, "header": "tr|A0A9J7FSL4-1|A0A9J7FSL4_CRIGR Isoform 1 of Tripartite motif-containing protein 29 OS=Cricetulus griseus OX=10029 GN=Trim29 PE=4 SV=1 CANONICAL=A0A9J7FSL4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSL4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSL4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FSL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL4" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 220, "end_pos": 260, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 254, "end_pos": 256 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 534, "end_pos": 536 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FSL7-1", "uniprot_ac": "A0A9J7FSL7", "uniprot_id": "A0A9J7FSL7_CRIGR", "mass": { "chemical_mass": 63978.0, "monoisotopic_mass": 63978.0 }, "refseq": { "ac": "XP_027266808", "name": "NADP-dependent malic enzyme isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266808" }, "gene_names": [ { "name": "Me1", "type": "recommended", "evidence": [ { "id": "A0A9J7FSL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL7" } ] }, { "name": "Me1", "type": "synonym", "evidence": [ { "id": "XP_027266808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266808" } ] } ], "protein_names": [ { "name": "Malic enzyme", "type": "recommended", "evidence": [ { "id": "A0A9J7FSL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL7/entry#names_and_taxonomy" } ] }, { "name": "NADP-dependent malic enzyme isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027266808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266808" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266808", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266808" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Me1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL7", "locus": {} } ], "crossref": [ { "id": "A0A9J7FSL7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FSL7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05312", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767908", "url": "https://www.ncbi.nlm.nih.gov/gene/100767908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767908", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767908", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FSL7", "url": "https://www.orthodb.org/?gene=A0A9J7FSL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23406", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23406", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23406:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23406:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03949", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03949", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266808", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266808", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FSL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPRAPRRRHTHQRGYLLTRDPHLNKDLAFTLEERQQLNIHGLLPPSFISQEIQVLRVVKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSNIEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAVVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPVILDVGTENEELLQDPLYIGLRQRRVRGPEYDKFLDEFMEAVSSKYGMNCLIQFEDFANRNAFRLLDKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIVMAMEKEGLSKENAIKKIWLVDSKGLIVKGRASLTEEKEVFAQEHEEMKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKVTKGRAIFASGSPFDPVTLPDGQTLYPGQGNNSYVFPGVALGVVACGLRHITDKVFLTTAEVISQQVSDKHLEEGRLYPPLNTIRDVSLKIAVQIVTDAYREKMATVYPEPPNKEEFVCSQMYSTNYDQILPDCYSWPEEAQKVQTKVSQ", "length": 572, "header": "tr|A0A9J7FSL7-1|A0A9J7FSL7_CRIGR Isoform 1 of Malic enzyme OS=Cricetulus griseus OX=10029 GN=Me1 PE=3 SV=1 CANONICAL=A0A9J7FSL7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FSL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL7/entry#A0A9J7FSL7-1", "sequence": { "sequence": "MEPRAPRRRHTHQRGYLLTRDPHLNKDLAFTLEERQQLNIHGLLPPSFISQEIQVLRVVKNFERLNSDFDRYLLLMDLQDRNEKLFYSVLMSNIEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDKGHIASVLNAWPEDVVKAVVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGVNPQQCLPVILDVGTENEELLQDPLYIGLRQRRVRGPEYDKFLDEFMEAVSSKYGMNCLIQFEDFANRNAFRLLDKYRNKYCTFNDDIQGTASVAVAGLLAALRITKNKLSDQTVLFQGAGEAALGIAHLIVMAMEKEGLSKENAIKKIWLVDSKGLIVKGRASLTEEKEVFAQEHEEMKNLEAIVQKIKPTALIGVAAIGGAFTEQILKDMAAFNERPIIFALSNPTSKAECSAEQCYKVTKGRAIFASGSPFDPVTLPDGQTLYPGQGNNSYVFPGVALGVVACGLRHITDKVFLTTAEVISQQVSDKHLEEGRLYPPLNTIRDVSLKIAVQIVTDAYREKMATVYPEPPNKEEFVCSQMYSTNYDQILPDCYSWPEEAQKVQTKVSQ", "length": 572, "header": "tr|A0A9J7FSL7-1|A0A9J7FSL7_CRIGR Isoform 1 of Malic enzyme OS=Cricetulus griseus OX=10029 GN=Me1 PE=3 SV=1 CANONICAL=A0A9J7FSL7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSL7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"A0A9J7FSM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8/entry#names_and_taxonomy" } ] }, { "name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027266831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266831" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266831", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266831" } ] }, { "annotation": "Together with BCKDHA forms the heterotetrameric E1 subunit of the mitochondrial branched-chain alpha-ketoacid dehydrogenase (BCKD) complex. The BCKD complex catalyzes the multi-step oxidative decarboxylation of alpha-ketoacids derived from the branched-chain amino-acids valine, leucine and isoleucine producing CO2 and acyl-CoA which is subsequently utilized to produce energy. The E1 subunit catalyzes the first step with the decarboxylation of the alpha-ketoacid forming an enzyme-product intermediate. A reductive acylation mediated by the lipoylamide cofactor of E2 extracts the acyl group from the E1 active site for the next step of the reaction.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MN96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MN96#function" }, { "database": "UniProtKB", "id": "ARBA00057409", "url": "https://www.uniprot.org/uniprotkb/ARBA00057409#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSM8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bckdhb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8", "locus": {} } ], "crossref": [ { "id": "cd07036", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07036", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774277", "url": "https://www.ncbi.nlm.nih.gov/gene/100774277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774277", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774277", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEAYYMA", "url": "https://omabrowser.org/oma/group/SEAYYMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MN96", "url": "https://www.orthodb.org/?gene=A0A8C2MN96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FSM8", "url": "https://www.orthodb.org/?gene=A0A9J7FSM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42980", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42980", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42980:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42980:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266831", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266831", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13457", "url": "https://www.rhea-db.org/rhea/13457", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "84639", "url": "https://www.rhea-db.org/rhea/84639", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "84643", "url": "https://www.rhea-db.org/rhea/84643", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MN96", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MN96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MN96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MN96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSM8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVASRAAGILRLRAAGAERRWCGPRCAGLVQGFLQPGGEDAAQKRRVAHFTFQPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEIIDLRTIVPWDMDTVCKSVVKTGRLLISHEAPLTGGFASEISSTVQCKHVIDDFLEKAKLTFLSQEQCCLTTIKFAVEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 421, "header": "tr|A0A9J7FSM8-1|A0A9J7FSM8_CRIGR Isoform 1 of 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) OS=Cricetulus griseus OX=10029 GN=Bckdhb PE=4 SV=1 CANONICAL=A0A9J7FSM8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MN96-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8/entry#A0A8C2MN96-1", "sequence": { "sequence": "MAAVASRAAGILRLRAAGAERRWCGPRCAGLVQGFLQPGGEDAAQKRRVAHFTFQPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEIIDLRTIVPWDMDTVCKSVVKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 390, "header": "tr|A0A8C2MN96-1|A0A8C2MN96_CRIGR Computationally mapped isoform of 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Cricetulus griseus OX=10029 GN=Bckdhb PE=4 SV=1 CANONICAL=A0A9J7FSM8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FSM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8/entry#A0A9J7FSM8-1", "sequence": { "sequence": "MAAVASRAAGILRLRAAGAERRWCGPRCAGLVQGFLQPGGEDAAQKRRVAHFTFQPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEIIDLRTIVPWDMDTVCKSVVKTGRLLISHEAPLTGGFASEISSTVQCKHVIDDFLEKAKLTFLSQEQCCLTTIKFAVEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 421, "header": "tr|A0A9J7FSM8-1|A0A9J7FSM8_CRIGR Isoform 1 of 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) OS=Cricetulus griseus OX=10029 GN=Bckdhb PE=4 SV=1 CANONICAL=A0A9J7FSM8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8/entry#A0A9J7GXI5-1", "sequence": { "sequence": "MAAVASRAAGILRLRAAGAERRWCGPRCAGLVQGFLQPGGEDAAQKRRVAHFTFQPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEIIDLRTIVPWDMDTVCKSVVKTGRLLISHEAPLTGGFASEISSTVQCKHVIDDFLEKAKLTFLSQEQCCLTTIKFAVVGIPNGVRKNVS", "length": 387, "header": "tr|A0A9J7GXI5-1|A0A9J7GXI5_CRIGR Computationally mapped isoform of 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) OS=Cricetulus griseus OX=10029 GN=Bckdhb PE=4 SV=1 CANONICAL=A0A9J7FSM8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8/entry#A0A9J7JJS1-1", "sequence": { "sequence": "MLPPGTFKIGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEIIDLRTIVPWDMDTVCKSVVKTGRLLISHEAPLTGGFASEISSTVQCKHVIDDFLEKAKLTFLSQEQCCLTTIKFAVEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 367, "header": "tr|A0A9J7JJS1-1|A0A9J7JJS1_CRIGR Computationally mapped isoform of 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) OS=Cricetulus griseus OX=10029 GN=Bckdhb PE=4 SV=1 CANONICAL=A0A9J7FSM8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSM8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSM8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774277", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774277", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RQL3-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "BCKDHB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAVAAAAAVAVGRLLRLRVARVEGHWHPLSGGGLLRGFLQPASADGDAAQKRQVAHFTFQPDPETVEYGQTQKMNLFQAVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVVPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPIEPYTIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAREKLGVSCEVIDLRTIIPWDVDTVCKSVIKTGRLLVSHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 396 }, "evidence": [ { "id": "A0A9J7FSM8", "url": "https://omabrowser.org/oma/group/A0A9J7FSM8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P21839-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "BCKDHB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAVAAFAGWLLRLRAAGADGPWRRLCGAGLSRGFLQSASAYGAAAQRRQVAHFTFQPDPEPVEYGQTQKMNLFQAVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVVPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVAAMAQEKLGVSCEVIDLRTILPWDVDTVCKSVIKTGRLLVSHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 392 }, "evidence": [ { "id": "A0A9J7FSM8", "url": "https://omabrowser.org/oma/group/A0A9J7FSM8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P21953-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "BCKDHB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 392 }, "evidence": [ { "id": "A0A9J7FSM8", "url": "https://omabrowser.org/oma/group/A0A9J7FSM8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35738-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "Bckdhb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVAARAGGLLRLGAAGAERRRRGLRCAALVQGFLQPAVDDASQKRRVAHFTFQPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 390 }, "evidence": [ { "id": "A0A9J7FSM8", "url": "https://omabrowser.org/oma/group/A0A9J7FSM8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q55FN7-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "bkdB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLRGNNIKKVNSLLVRSFHSTVGNRSGGPSTPINYPSLEIENAGEKQKMNLFQAINNGMDIAMQKDSKAVVFGEDVGFGGVFRCTVGLRDKYGASRVFNTPLCEQGIAGFAIGLAAQGATPIAEIQFADYIFPAFDQIVNEAAKYRYRSGGQFDCGSLTIRSPYGAVGHGGHYHSQSPESYFGHTPGLKVVIPSTPIEAKGLLLASIREKDPVIFFEPKLMYRSAVEEVPIGDYEIPLGKARIVKEGKDITIIGWGAQMRVLLQAVNMAEEKLGISCELIDLRTIQPWDVETVVESVKKTGRVVISHEAPKTGGWAAEISATIQERCFLHLEAPIQRVCGYDTPFPLIFEKFYVPDHLKNFESIKKTMVY", "length": 370 }, "evidence": [ { "id": "A0A9J7FSM8", "url": "https://omabrowser.org/oma/group/A0A9J7FSM8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6P3A8-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "Bckdhb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVAARAGGLLWLRAAGAERRRCGLRCAALVQGFLQPGGEDTAQKRRVAHFTFHPDPESLQYGQTQKMNLFQSITSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRAPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAAVEQVPVEPYKIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAQEKLGVSCEVIDLRTIVPWDVDTVCKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRVCGYDTPFPHIFEPFYIPDKWKCYDALRKMINY", "length": 390 }, "evidence": [ { "id": "A0A9J7FSM8", "url": "https://omabrowser.org/oma/group/A0A9J7FSM8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7PLE6-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "gene_name": "Bckdhb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNIVSTQLGNSLYNCVRSNLRWPLWTRSHFTYYPTRMGTGKRMNMFNAINNAMDLALDENKSALLFGEDVGFGGVFRCSVNLRDKYGSQRVFNTPLCEQGIAGFAIGVANTGATAIAEIQFADYIFPSFDQIVNEAAKYRYRSGGLFDCGSLTFRVPCGAVGHGALYHSQSPEAYFAHTPGLRVVVPRGPIKAKGLILACIRDPNPCIVFEPKTLYRAAVEEVPAEYYTSQLGKADILRHGKDVTLIGWGTQVHVLLEVAEIAKSTLNIDCEVIDLVSILPWDAITICTSAKKTGRVIIAHEAPLTQGFGSELASYIQEKCFLHLEAPVKRVAGWDTPFPHVFEPFYMPDKHRCLSAINDIVNF", "length": 364 }, "evidence": [ { "id": "A0A9J7FSM8", "url": "https://omabrowser.org/oma/group/A0A9J7FSM8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9SAV3-1", "protein_name": "2-oxoisovalerate dehydrogenase subunit beta 1, mitochondrial", "gene_name": "BCDH BETA1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAALLGRSCRKLSFPSLSHGARRVSTETGKPLNLYSAINQALHIALDTDPRSYVFGEDVGFGGVFRCTTGLAERFGKNRVFNTPLCEQGIVGFGIGLAAMGNRAIVEIQFADYIYPAFDQIVNEAAKFRYRSGNQFNCGGLTIRAPYGAVGHGGHYHSQSPEAFFCHVPGIKVVIPRSPREAKGLLLSCIRDPNPVVFFEPKWLYRQAVEEVPEHDYMIPLSEAEVIREGNDITLVGWGAQLTVMEQACLDAEKEGISCELIDLKTLLPWDKETVEASVKKTGRLLISHEAPVTGGFGAEISATILERCFLKLEAPVSRVCGLDTPFPLVFEPFYMPTKNKILDAIKSTVNY", "length": 352 }, "evidence": [ { "id": "A0A9J7FSM8", "url": "https://omabrowser.org/oma/group/A0A9J7FSM8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "response to nutrient", "id": "GO:0007584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007584", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSM8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSM8" } ], "pmid": "" }, { "name": "branched-chain amino acid catabolic process", "id": "GO:0009083", "url": 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Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265354", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265354" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100771017", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ0", "locus": {} } ], "crossref": [ { "id": "A0A9J7FSQ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FSQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771017", "url": "https://www.ncbi.nlm.nih.gov/gene/100771017", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771017", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771017", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FSQ0", "url": "https://www.orthodb.org/?gene=A0A9J7FSQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265354", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265354", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAREPGASTALNVQSAEEGTGLLVVKVEQEEAFPLPEEASWMGSPGHDRSRQRFRAFRYPEEAGPRQALSRLRELCRQWLRPDMHSKEQILELLVLEQFLTILPGELQAWVREQHPDSGEEVVALLEYLERQLDETPPQVPTGEWSRELLCCKVALLMPSQNSQSSHSQPMKCLLKHESQESLECSPLQARGLEMKPETRDLHPAEEYTEHKPEQPRSLLAEDTVGIPAGAETSEQEGKLQTTQKNATRNKRHYCPECGKTFAQSSGLTKHRRIHTGEKPYECEDCGKAFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYKCDNCGKTFTQSCSLLEHHKIHTGEKPFQCNLCGKAFRRSSHLLRHQRIHSDKTAHTPLHREAWEGQSRVESQWDDTETPMTYQCNECERSFTQNRSLIEHKKIHTGEKPYQCGACGKGFTRTSYLVQHQRSHVGKKIVSQ", "length": 478, "header": "tr|A0A9J7FSQ0-1|A0A9J7FSQ0_CRIGR Isoform 1 of Zinc finger protein 307 OS=Cricetulus griseus OX=10029 GN=LOC100771017 PE=3 SV=1 CANONICAL=A0A9J7FSQ0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FSQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ0/entry#A0A9J7FSQ0-1", "sequence": { "sequence": "MAREPGASTALNVQSAEEGTGLLVVKVEQEEAFPLPEEASWMGSPGHDRSRQRFRAFRYPEEAGPRQALSRLRELCRQWLRPDMHSKEQILELLVLEQFLTILPGELQAWVREQHPDSGEEVVALLEYLERQLDETPPQVPTGEWSRELLCCKVALLMPSQNSQSSHSQPMKCLLKHESQESLECSPLQARGLEMKPETRDLHPAEEYTEHKPEQPRSLLAEDTVGIPAGAETSEQEGKLQTTQKNATRNKRHYCPECGKTFAQSSGLTKHRRIHTGEKPYECEDCGKAFIGSSALVIHQRVHTGEKPYECEECGKVFSHSSNLIKHQRTHTGEKPYKCDNCGKTFTQSCSLLEHHKIHTGEKPFQCNLCGKAFRRSSHLLRHQRIHSDKTAHTPLHREAWEGQSRVESQWDDTETPMTYQCNECERSFTQNRSLIEHKKIHTGEKPYQCGACGKGFTRTSYLVQHQRSHVGKKIVSQ", "length": 478, "header": "tr|A0A9J7FSQ0-1|A0A9J7FSQ0_CRIGR Isoform 1 of Zinc finger protein 307 OS=Cricetulus griseus OX=10029 GN=LOC100771017 PE=3 SV=1 CANONICAL=A0A9J7FSQ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ0" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSQ0", "url": 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predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265863" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Scube2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ3", "locus": {} } ], "crossref": [ { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", 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"length": 1020, "header": "tr|A0A9J7FSQ3-1|A0A9J7FSQ3_CRIGR Isoform 1 of Signal peptide, CUB and EGF-like domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Scube2 PE=4 SV=1 CANONICAL=A0A9J7FSQ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSQ3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264659" } ] }, { "annotation": "Protein associated with the U5 snRNP, during its maturation and its post-splicing recycling and which is required for spliceosomal tri-snRNP complex assembly in the nucleus. Has a molecular sequestering activity and transiently hinders SNRNP200 binding sites for constitutive splicing factors that intervene later during the assembly of the spliceosome and splicing. Together with its molecular sequestering activity, may also function as a molecular adapter and placeholder, coordinating the assembly of the U5 snRNP and its association with the U4/U6 di-snRNP.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6#function" }, { "database": "UniProtKB", "id": "ARBA00045970", "url": "https://www.uniprot.org/uniprotkb/ARBA00045970#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tssc4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6", "locus": {} } ], "crossref": [ { "id": "100759348", "url": "https://www.ncbi.nlm.nih.gov/gene/100759348", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759348", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759348", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FSW6", "url": "https://www.orthodb.org/?gene=A0A9J7FSW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13445", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13445", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13445:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13445:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15264", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15264", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027264659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264659", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FSW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAETGLEAEEPTEDDTLPSDTVSLSDSDSDLSLPSGAEVQVLSPERISGEAQEDSGPDEPPSPPTGVPTTAVQPFHLRGMSSTFSQRSHSIFDCLESAVRQAPPSAPQTSVTENGNFKRPVAPPSQTPAGNLSRVHGSTGPTRVPPVPDYVSHPERWTKYSLEDATEVSEQSNRAAALAFLGSRSLASPTDYVPSFNQDPSSCGEGRVVFTKPIRGSETRAERKRVLKKGDVSNAVSEASVELAHLAGPELEEWSGHQGLQEAVIPSGADHPGSSSDPTGMEAVGFHGSKKRSREHFRNRDSNPEGPGSERGPSV", "length": 317, "header": "tr|A0A9J7FSW6-1|A0A9J7FSW6_CRIGR Isoform 1 of U5 small nuclear ribonucleoprotein TSSC4 OS=Cricetulus griseus OX=10029 GN=Tssc4 PE=3 SV=1 CANONICAL=A0A9J7FSW6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FSW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6/entry#A0A9J7FSW6-1", "sequence": { "sequence": "MAEAETGLEAEEPTEDDTLPSDTVSLSDSDSDLSLPSGAEVQVLSPERISGEAQEDSGPDEPPSPPTGVPTTAVQPFHLRGMSSTFSQRSHSIFDCLESAVRQAPPSAPQTSVTENGNFKRPVAPPSQTPAGNLSRVHGSTGPTRVPPVPDYVSHPERWTKYSLEDATEVSEQSNRAAALAFLGSRSLASPTDYVPSFNQDPSSCGEGRVVFTKPIRGSETRAERKRVLKKGDVSNAVSEASVELAHLAGPELEEWSGHQGLQEAVIPSGADHPGSSSDPTGMEAVGFHGSKKRSREHFRNRDSNPEGPGSERGPSV", "length": 317, "header": "tr|A0A9J7FSW6-1|A0A9J7FSW6_CRIGR Isoform 1 of U5 small nuclear ribonucleoprotein TSSC4 OS=Cricetulus griseus OX=10029 GN=Tssc4 PE=3 SV=1 CANONICAL=A0A9J7FSW6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759348", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759348", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FSX9-1", "uniprot_ac": "A0A9J7FSX9", "uniprot_id": "A0A9J7FSX9_CRIGR", "mass": { "chemical_mass": 17516.0, "monoisotopic_mass": 17516.0 }, "refseq": { "ac": "XP_027266060", "name": "acyl carrier protein, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266060" }, "gene_names": [ { "name": "Ndufab1", "type": "recommended", "evidence": [ { "id": "A0A9J7FSX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9" } ] }, { "name": "Ndufab1", "type": "synonym", "evidence": [ { "id": "XP_027266060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266060" } ] } ], "protein_names": [ { "name": "Acyl carrier protein", "type": "recommended", "evidence": [ { "id": "A0A9J7FSX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9/entry#names_and_taxonomy" } ] }, { "name": "acyl carrier protein, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_027266060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266060" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266060" } ] }, { "annotation": "Carrier of the growing fatty acid chain in fatty acid biosynthesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9#function" }, { "database": "UniProtKB", "id": "RU000722", "url": "https://www.uniprot.org/uniprotkb/RU000722#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ndufab1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9", "locus": {} } ], "crossref": [ { "id": "A0A9J7FSX9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FSX9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100765100", "url": "https://www.ncbi.nlm.nih.gov/gene/100765100", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765100", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765100", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FSX9", "url": "https://www.orthodb.org/?gene=A0A9J7FSX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20863", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20863", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20863:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20863:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00550", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00550", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266060", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FSX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARVLSACVRRLPVAFAPLLRLPTLALARPLSTTLCSEGTRRKLGTLQPVLALTQVPGRVTHLCRQYSDAPPLTLEGIKDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE", "length": 156, "header": "tr|A0A9J7FSX9-1|A0A9J7FSX9_CRIGR Isoform 1 of Acyl carrier protein OS=Cricetulus griseus OX=10029 GN=Ndufab1 PE=3 SV=1 CANONICAL=A0A9J7FSX9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FSX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9/entry#A0A9J7FSX9-1", "sequence": { "sequence": "MAARVLSACVRRLPVAFAPLLRLPTLALARPLSTTLCSEGTRRKLGTLQPVLALTQVPGRVTHLCRQYSDAPPLTLEGIKDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIMAMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE", "length": 156, "header": "tr|A0A9J7FSX9-1|A0A9J7FSX9_CRIGR Isoform 1 of Acyl carrier protein OS=Cricetulus griseus OX=10029 GN=Ndufab1 PE=3 SV=1 CANONICAL=A0A9J7FSX9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765100", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765100", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9" } ], "pmid": "" }, { "name": "respiratory chain complex I", "id": "GO:0045271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045271", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "acyl binding", "id": "GO:0000035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000035", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9" } ], "pmid": "" }, { "name": "acyl carrier activity", "id": "GO:0000036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000036", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "respiratory electron transport chain", "id": "GO:0022904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022904", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266114" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT05" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dennd5a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT05", "locus": {} } ], "crossref": [ { "id": "cd01757", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01757", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17690", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17690", "database": "CDD", 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"length": 1437, "header": "tr|A0A9J7FT05-1|A0A9J7FT05_CRIGR Isoform 1 of DENN domain-containing protein 5A isoform X3 OS=Cricetulus griseus OX=10029 GN=Dennd5a PE=3 SV=1 CANONICAL=A0A9J7FT05-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT05" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767226", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767226", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT05" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT05", "url": 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264317" } ] }, { "annotation": "Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. 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Required for normal progress through the cell cycle.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT18#function" }, { "database": "UniProtKB", "id": "ARBA00058269", "url": "https://www.uniprot.org/uniprotkb/ARBA00058269#function" }, { "database": "UniProtKB", "id": "A0A8C2LKK0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKK0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT18" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arl2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT18", "locus": {} } ], "crossref": [ { "id": "A0A9J7FT18", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FT18", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04154", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04154", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760039", "url": "https://www.ncbi.nlm.nih.gov/gene/100760039", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045873", "url": 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"https://www.uniprot.org/uniprotkb/A0A9J7FT18" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT18" } ], "pmid": "" }, { "name": "GDP binding", "id": "GO:0019003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019003", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT18" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT18" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT18", 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FT76-1", "uniprot_ac": "A0A9J7FT76", "uniprot_id": "A0A9J7FT76_CRIGR", "mass": { "chemical_mass": 132715.0, "monoisotopic_mass": 132715.0 }, "refseq": { "ac": "XP_007642727", "name": "PR domain zinc finger protein 10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642727" }, "gene_names": [ { "name": "Prdm10", "type": "recommended", "evidence": [ { "id": "A0A9J7FT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76" } ] }, { "name": "Prdm10", "type": "synonym", "evidence": [ { "id": "XP_007642727", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642727" } ] } ], "protein_names": [ { "name": "PR domain zinc finger protein 10", "type": "recommended", "evidence": [ { "id": "A0A9J7FT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76/entry#names_and_taxonomy" } ] }, { "name": "PR domain zinc finger protein 10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007642727", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642727" } ] }, { "name": "PR domain-containing protein 10", "type": "synonym", "evidence": [ { "id": "A0A9J7FT76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007642727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642727" } ] }, { "annotation": "Transcriptional activator, essential for early embryonic development and survival of embryonic stem cells (ESCs). Supports cell growth and survival during early development by transcriptionally activating the expression of the translation initiation factor EIF3B, to sustain global translation. Activates the transcription of FLNC.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76#function" }, { "database": "UniProtKB", "id": "ARBA00093328", "url": "https://www.uniprot.org/uniprotkb/ARBA00093328#function" }, { "database": "UniProtKB", "id": "A0A9J7FT77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT77#function" }, { "database": "UniProtKB", "id": "A0A8C2MSK1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prdm10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76", "locus": {} } ], "crossref": [ { "id": "cd19194", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19194", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756394", "url": "https://www.ncbi.nlm.nih.gov/gene/100756394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756394", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756394", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MSK1", "url": "https://www.orthodb.org/?gene=A0A8C2MSK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FT76", "url": "https://www.orthodb.org/?gene=A0A9J7FT76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FT77", "url": "https://www.orthodb.org/?gene=A0A9J7FT77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21549", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21549", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007642727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642727", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MSK1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FT76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FT76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FT77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FT77-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT77-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYKTHECSLSCPAAVGGSDLELSNKDKMDSKDESSHVWPTSADHEQNTAQVHFVPDAGTVAQIVYTDDQVRPPQQVVYTADGASYTSVDGPEHTLVYIHPVEAAQTLFTDPAQVAYVQQDATAQQVLPSIEGVDGSDPLATLQNPIARLDAKEEEEEEEEDEDEDTEEEEEEDAEDTDVDDWQPDPPRPFDPHDLWCEECNNAHSSVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKDRDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFTRTRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPAALNGLDQPEQASIPIPQLPQETPSSLEQEPETHTLHLQPQQEETVVPAQTTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSASLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLPNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQQPQHIQLQVVQVAPATSPHQSQQSTVDVGQLHDPQTYTQHAIQVQHIQVTEPTAAAPSSSQVAGQPLSPSTQQAQQGLSPSHIQGSSSTQGQTLQQQQNSSVQHTYLPNAWNSFRGYSSEIQMMTLPPGQFVITDSSVATPVTSGQVKAVTPGHYVLSESQPELEEKQASTLSGAVQVQPSAHSDSLDSTSPSQQQTTQYIITTTTNGNGSSEVHITKP", "length": 1174, "header": "tr|A0A9J7FT76-1|A0A9J7FT76_CRIGR Isoform 1 of PR domain zinc finger protein 10 OS=Cricetulus griseus OX=10029 GN=Prdm10 PE=4 SV=1 CANONICAL=A0A9J7FT76-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MSK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76/entry#A0A8C2MSK1-1", "sequence": { "sequence": "MYKTHECSLSCPAAVGGSDLELSNKDKMDSKDESSHVWPTSADHEQNTAQVHFVPDAGTVAQIVYTDDQVRPPQQVVYTADGASYTSVDGPEHTLVYIHPVEAAQTLFTDPAQVAYVQQDATAQQVLPSIEGVDGSDPLATLQNPIARLDAKEEEEEEEEDEDEDTEEEEEEDAEDTDVDDWQPDPPRPFDPHDLWCEECNNAHSSVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKDRDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFTRTRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQEQFDEAEPAALNGLDQPEQASIPIPQLPQETPSSLEQEPETHTLHLQPQQEETVVPAQTTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSASLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLPNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQQPQHIQLQVVQVAPATSPHQSQQSTVDVGQLHDPQTYTQHAIQVQHIQVTEPTAAAPSSSQVAGQPLSPSTQQAQQGLSPSHIQGSSSTQGQTLQQQQNSSVQHTYLPNAWNSFRGYSSEIQMMTLPPGQFVITDSSVATPVTSGQVKAVTPGHYVLSESQPELEEKQASTLSGAVQVQPSAHSDSLDSTSPSQQQTTQYIITTTTNGNGSSEVHITKP", "length": 1166, "header": "tr|A0A8C2MSK1-1|A0A8C2MSK1_CRIGR Computationally mapped isoform of PR domain zinc finger protein 10 OS=Cricetulus griseus OX=10029 GN=Prdm10 PE=4 SV=1 CANONICAL=A0A9J7FT76-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FT76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76/entry#A0A9J7FT76-1", "sequence": { "sequence": "MYKTHECSLSCPAAVGGSDLELSNKDKMDSKDESSHVWPTSADHEQNTAQVHFVPDAGTVAQIVYTDDQVRPPQQVVYTADGASYTSVDGPEHTLVYIHPVEAAQTLFTDPAQVAYVQQDATAQQVLPSIEGVDGSDPLATLQNPIARLDAKEEEEEEEEDEDEDTEEEEEEDAEDTDVDDWQPDPPRPFDPHDLWCEECNNAHSSVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKDRDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFTRTRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPAALNGLDQPEQASIPIPQLPQETPSSLEQEPETHTLHLQPQQEETVVPAQTTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSASLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLPNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQQPQHIQLQVVQVAPATSPHQSQQSTVDVGQLHDPQTYTQHAIQVQHIQVTEPTAAAPSSSQVAGQPLSPSTQQAQQGLSPSHIQGSSSTQGQTLQQQQNSSVQHTYLPNAWNSFRGYSSEIQMMTLPPGQFVITDSSVATPVTSGQVKAVTPGHYVLSESQPELEEKQASTLSGAVQVQPSAHSDSLDSTSPSQQQTTQYIITTTTNGNGSSEVHITKP", "length": 1174, "header": "tr|A0A9J7FT76-1|A0A9J7FT76_CRIGR Isoform 1 of PR domain zinc finger protein 10 OS=Cricetulus griseus OX=10029 GN=Prdm10 PE=4 SV=1 CANONICAL=A0A9J7FT76-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FT77-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76/entry#A0A9J7FT77-1", "sequence": { "sequence": "MYKTHECSLSCPAAVGGSDLELSNKDKMDSKDESSHVWPTSADHEQNTAQVHFVPDAGTVAQIVYTDDQVRPPQQVVYTADGASYTSVDGPEHTLVYIHPVEAAQTLFTDPAQVAYVQQDATAQQVLPSIEGVDGSDPLATLQNPIARLDAKEEEEEEEEDEDEDTEEEEEEDAEDTDVDDWQPDPPRPFDPHDLWCEECNNAHSSVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKDRDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFTRTRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQFDEAEPAALNGLDQPEQASIPIPQLPQETPSSLEQEPETHTLHLQPQQEETVVPAQTTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSASLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLPNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQQPQHIQLQVVQVAPATSPHQSQQSTVDVGQLHDPQTYTQHAIQVQHIQVTEPTAAAPSSSQVAGQPLSPSTQQAQQGLSPSHIQGSSSTQGQTLQQQQNSSVQHTYLPNAWNSFRGYSSEIQMMTLPPGQFVITDSSVATPVTSGQVKAVTPGHYVLSESQPELEEKQASTLSGAVQVQPSAHSDSLDSTSPSQQQTTQYIITTTTNGNGSSEVHITKP", "length": 1164, "header": "tr|A0A9J7FT77-1|A0A9J7FT77_CRIGR Computationally mapped isoform of PR domain zinc finger protein 10 OS=Cricetulus griseus OX=10029 GN=Prdm10 PE=4 SV=1 CANONICAL=A0A9J7FT76-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1106, "start_aa": "Thr", "end_pos": 1106, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1106", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT76" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FTT0-1", "uniprot_ac": "A0A9J7FTT0", "uniprot_id": "A0A9J7FTT0_CRIGR", "mass": { "chemical_mass": 176772.0, "monoisotopic_mass": 176772.0 }, "refseq": { "ac": "XP_027268216", "name": "roundabout homolog 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268216" }, "gene_names": [ { "name": "Robo1", "type": "recommended", "evidence": [ { "id": "A0A9J7FTT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ] }, { "name": "Robo1", "type": "synonym", "evidence": [ { "id": "XP_027268216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268216" } ] } ], "protein_names": [ { "name": "Roundabout homolog 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7FTT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0/entry#names_and_taxonomy" } ] }, { "name": "roundabout homolog 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027268216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268216" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268216", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268216" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Robo1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0", "locus": {} } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05724", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05724", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05725", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05725", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05726", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05726", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07693", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07693", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20952", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20952", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771010", "url": "https://www.ncbi.nlm.nih.gov/gene/100771010", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771010", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771010", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FTT0", "url": "https://www.orthodb.org/?gene=A0A9J7FTT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231:SF243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231:SF243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268216", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268216", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FTB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVF6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIAEPAHFYLFGLLCLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSALDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVMAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTVVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLETGVLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSVEVHWTVDQQSQYIQGYKILYRPSGAGHSESEWLVFEVRTPTKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPRSVTVSKNDGNGTAILVTWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHGNPVSPEDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIRKVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTASNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQANLSNNMNNGGGDSSEKHWKPPGQQKQEVAPIQYNIMEQNKLNKDYRANDTIPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKAPKQGGMNWADLLPPPPAHPPPHSNSEDYSLSVDESYDQEMPCPVPPARMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDVGHMAHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDASGRRHFHASQCPRPTSPVSTDSNMSAAVIQKTRPTKKQKHQPGHLRREAYTDDLPPPPVPPPAIKSPTVQSKAQLEVRPVMVPKLASIEARTDRSSDRKGGSYKGREALDGRQVPDLRTNPSDPREAQDQQNDGKGRGNKAAKRDLPPAKTHLVQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGYERGDDNNEELEETES", "length": 1615, "header": "tr|A0A9J7FTT0-1|A0A9J7FTT0_CRIGR Isoform 1 of Roundabout homolog 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Robo1 PE=3 SV=1 CANONICAL=A0A9J7FTT0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FTB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0/entry#A0A9J7FTB2-1", "sequence": { "sequence": "MIAEPAHFYLFGLLCLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSALDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVMAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTVVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLETGVLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSVEVHWTVDQQSQYIQGYKILYRPSGAGHSESEWLVFEVRTPTKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPRSVTVSKNDGNGTAILVTWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHGNPVSPEDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIRKVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTASNGNSDSNLTTYSRPGQPTPYATTQLIQANLSNNMNNGGGDSSEKHWKPPGQQKQEVAPIQYNIMEQNKLNKDYRANDTIPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKAPKQGGMNWADLLPPPPAHPPPHSNSEDYSLSVDESYDQEMPCPVPPARMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDVGHMAHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDASGRRHFHASQCPRPTSPVSTDSNMSAAVIQKTRPTKKQKHQPGHLRREAYTDDLPPPPVPPPAIKSPTVQSKAQLEVRPVMVPKLASIEARTDRSSDRKGGSYKGREALDGRQVPDLRTNPSDPREAQDQQNDGKGRGNKAAKRDLPPAKTHLVQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGYERGDDNNEELEETES", "length": 1560, "header": "tr|A0A9J7FTB2-1|A0A9J7FTT0_CRIGR Computationally mapped isoform of Roundabout homolog 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Robo1 PE=3 SV=1 CANONICAL=A0A9J7FTT0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0/entry#A0A9J7FTT0-1", "sequence": { "sequence": "MIAEPAHFYLFGLLCLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSALDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVMAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTVVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLETGVLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSVEVHWTVDQQSQYIQGYKILYRPSGAGHSESEWLVFEVRTPTKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPRSVTVSKNDGNGTAILVTWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHGNPVSPEDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIRKVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTASNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQANLSNNMNNGGGDSSEKHWKPPGQQKQEVAPIQYNIMEQNKLNKDYRANDTIPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKAPKQGGMNWADLLPPPPAHPPPHSNSEDYSLSVDESYDQEMPCPVPPARMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDVGHMAHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDASGRRHFHASQCPRPTSPVSTDSNMSAAVIQKTRPTKKQKHQPGHLRREAYTDDLPPPPVPPPAIKSPTVQSKAQLEVRPVMVPKLASIEARTDRSSDRKGGSYKGREALDGRQVPDLRTNPSDPREAQDQQNDGKGRGNKAAKRDLPPAKTHLVQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGYERGDDNNEELEETES", "length": 1615, "header": "tr|A0A9J7FTT0-1|A0A9J7FTT0_CRIGR Isoform 1 of Roundabout homolog 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Robo1 PE=3 SV=1 CANONICAL=A0A9J7FTT0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0/entry#A0A9J7FVF6-1", "sequence": { "sequence": 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"length": 1606, "header": "tr|A0A9J7FVF6-1|A0A9J7FVF6_CRIGR Computationally mapped isoform of Roundabout homolog 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Robo1 PE=3 SV=1 CANONICAL=A0A9J7FTT0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0/entry#A0A9J7FXM2-1", "sequence": { "sequence": "MIAEPAHFYLFGLLCLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYICVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSALDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVMAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTVVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLETGVLQIRYAKLGDTGRYTCTASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSKNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETFAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVPPTSQGVDHKQVQRELGNVVLHLHNPTILSSSSVEVHWTVDQQSQYIQGYKILYRPSGAGHSESEWLVFEVRTPTKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPRSVTVSKNDGNGTAILVTWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPSLVPGIRYSVEVAASTGAGPGVKSEPQFIQLDSHGNPVSPEDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIRKVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTASNGNSDSNLTTYSRPGQPTPYATTQLIQANLSNNMNNGGGDSSEKHWKPPGQQKQEVAPIQYNIMEQNKLNKDYRANDTIPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKAPKQGGMNWADLLPPPPAHPPPHSNSEDYSLSVDESYDQEMPCPVPPARMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDVGHMAHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDASGRRHFHASQCPRPTSPVSTDSNMSAAVIQKTRPTKKQKHQPGHLRREAYTDDLPPPPVPPPAIKSPTVQSKAQLEVRPVMVPKLASIEARTDRSSDRKGGSYKGREALDGRQVPDLRTNPSDPREAQDQQNDGKGRGNKAAKRDLPPAKTHLVQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGYERGDDNNEELEETES", "length": 1551, "header": "tr|A0A9J7FXM2-1|A0A9J7FXM2_CRIGR Computationally mapped isoform of Roundabout homolog 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Robo1 PE=3 SV=1 CANONICAL=A0A9J7FTT0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1204, "start_aa": "Thr", "end_pos": 1204, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1204", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 519, "start_aa": "Thr", "end_pos": 519, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr519", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTB2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTB2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771010", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771010", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "chemotaxis", "id": "GO:0006935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006935", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ], "pmid": "" }, { "name": "axon midline choice point recognition", "id": "GO:0016199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016199", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ], "pmid": "" }, { "name": "Roundabout signaling pathway", "id": "GO:0035385", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035385", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ], "pmid": "" }, { "name": "regulation of multicellular organismal process", "id": "GO:0051239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051239", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ], "pmid": "" }, { "name": "regulation of anatomical structure morphogenesis", "id": "GO:0022603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022603", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "axon guidance receptor activity", "id": "GO:0008046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008046", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1046, "end_pos": 1048, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1093, "end_pos": 1095, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1103, "end_pos": 1105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1115, "end_pos": 1117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1346, "end_pos": 1348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1413, "end_pos": 1415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" }, { "start_pos": 784, "end_pos": 786, "annotation": "n_glycosylation_sequon" }, { "start_pos": 791, "end_pos": 793, "annotation": "n_glycosylation_sequon" }, { "start_pos": 930, "end_pos": 932, "annotation": "n_glycosylation_sequon" }, { "start_pos": 969, "end_pos": 971, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FTT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 527, "end_pos": 621, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FTT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": 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"end_pos": 971 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"header": "tr|A0A9J7FTC2-1|A0A9J7FTC2_CRIGR Isoform 1 of Vitamin K-dependent protein S OS=Cricetulus griseus OX=10029 GN=Pros1 PE=4 SV=1 CANONICAL=A0A9J7FTC2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265011" } ] }, { "annotation": "Possible taste receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTC8#function" }, { "database": "UniProtKB", "id": "ARBA00053672", "url": "https://www.uniprot.org/uniprotkb/ARBA00053672#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTC8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772515", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTC8", "locus": {} } ], "crossref": [ { "id": "A0A9J7FTC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FTC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15232", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15232", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772515", "url": "https://www.ncbi.nlm.nih.gov/gene/100772515", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772515", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772515", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FTC8", "url": "https://www.orthodb.org/?gene=A0A9J7FTC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265011", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265011", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FTC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTC8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSPNQTMVTEFVLEGFSEHPTLQFLLIGCFLTLYTVALIGNTVIIALVTSSTGLHSPMYFFLCNLATMDIVCTSSVLPKALLGLVSEENTISFKGCMAQLFFLLWSLSSELLLLTVMAYDRYVAICHPLHYTSRMSPHLCGALALGVWSICALNASVHTGLMTRLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLMADAFYGGINFFLTLLSYGCIIASVLRMRSAEGKKKAFSTCSSHLIVVCVYYSSVFCAYISPASSYSPERSKVTSVLYSVLSPTLNPLIYTLRNKDVKLALGRLLSSFSH", "length": 310, "header": "tr|A0A9J7FTC8-1|A0A9J7FTC8_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100772515 PE=3 SV=1 CANONICAL=A0A9J7FTC8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FTC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTC8/entry#A0A9J7FTC8-1", "sequence": { "sequence": "MLSPNQTMVTEFVLEGFSEHPTLQFLLIGCFLTLYTVALIGNTVIIALVTSSTGLHSPMYFFLCNLATMDIVCTSSVLPKALLGLVSEENTISFKGCMAQLFFLLWSLSSELLLLTVMAYDRYVAICHPLHYTSRMSPHLCGALALGVWSICALNASVHTGLMTRLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLMADAFYGGINFFLTLLSYGCIIASVLRMRSAEGKKKAFSTCSSHLIVVCVYYSSVFCAYISPASSYSPERSKVTSVLYSVLSPTLNPLIYTLRNKDVKLALGRLLSSFSH", "length": 310, "header": "tr|A0A9J7FTC8-1|A0A9J7FTC8_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100772515 PE=3 SV=1 CANONICAL=A0A9J7FTC8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"UniProtKB", "id": "A0A9J7FTC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FTC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTC8" }, { "id": "PS50262", "database": "PROSITE", "url": 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509888" }, "gene_names": [ { "name": "LOC100752249", "type": "recommended", "evidence": [ { "id": "A0A9J7FTE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTE9" } ] }, { "name": "LOC100752249", "type": "synonym", "evidence": [ { "id": "XP_003509888", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509888" } ] } ], "protein_names": [ { "name": "Prolactin-3D4-like", "type": "synonym", "evidence": [ { "id": "A0A9J7FTE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTE9/entry#names_and_taxonomy" } ] }, { "name": "prolactin-3D4-like", "type": "synonym", "evidence": [ { "id": "XP_003509888", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509888" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614777.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003509888.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509888", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509888" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTE9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100752249", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTE9", "locus": {} } ], "crossref": [ { "id": "A0A9J7FTE9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FTE9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10288", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10288", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752249", "url": "https://www.ncbi.nlm.nih.gov/gene/100752249", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752249", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752249", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FTE9", "url": "https://www.orthodb.org/?gene=A0A9J7FTE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11417", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11417", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11417:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11417:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509888", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509888", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FTE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLAFTLPRSAGMYMLLLVSTLLLWEHVASKPSGLVSIEALYNRVVEHSHTSYVLAADIYREFDLNFFKRSWFTDRTLSLCHTASIYTPETRQEVHDTKTEDLLKAIVNITHSWEEPLKHLLSAVPTLPGASDNMLKSANAVKEKNHILLEGIEAILNKTQVEVEDDTYPDWSGLSDLQSSDEETRLFEFFNLCRCLRRDTHKVDTFLKVLRCRVVYNNECMYYQ", "length": 225, "header": "tr|A0A9J7FTE9-1|A0A9J7FTE9_CRIGR Isoform 1 of Prolactin-3D4-like OS=Cricetulus griseus OX=10029 GN=LOC100752249 PE=3 SV=1 CANONICAL=A0A9J7FTE9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FTE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTE9/entry#A0A9J7FTE9-1", "sequence": { "sequence": "MKLAFTLPRSAGMYMLLLVSTLLLWEHVASKPSGLVSIEALYNRVVEHSHTSYVLAADIYREFDLNFFKRSWFTDRTLSLCHTASIYTPETRQEVHDTKTEDLLKAIVNITHSWEEPLKHLLSAVPTLPGASDNMLKSANAVKEKNHILLEGIEAILNKTQVEVEDDTYPDWSGLSDLQSSDEETRLFEFFNLCRCLRRDTHKVDTFLKVLRCRVVYNNECMYYQ", "length": 225, "header": "tr|A0A9J7FTE9-1|A0A9J7FTE9_CRIGR Isoform 1 of Prolactin-3D4-like OS=Cricetulus griseus OX=10029 GN=LOC100752249 PE=3 SV=1 CANONICAL=A0A9J7FTE9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"ac": "XP_027267511", "name": "beta-galactosidase-1-like protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267511" }, "gene_names": [ { "name": "LOC100757754", "type": "recommended", "evidence": [ { "id": "A0A9J7FTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK0" } ] }, { "name": "LOC100757754", "type": "synonym", "evidence": [ { "id": "XP_027267511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267511" } ] } ], "protein_names": [ { "name": "Beta-galactosidase", "type": "recommended", "evidence": [ { "id": "A0A9J7FTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK0/entry#names_and_taxonomy" } ] }, { "name": "3.2.1.23", "type": "synonym", "evidence": [ { "id": "A0A9J7FTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK0/entry#names_and_taxonomy" } ] }, { "name": "beta-galactosidase-1-like protein 2 isoform X1", "type": 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267511" } ] }, { "annotation": "Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK0#function" }, { "database": "UniProtKB", "id": "ARBA00002691", "url": "https://www.uniprot.org/uniprotkb/ARBA00002691#function" }, { "database": "UniProtKB", "id": "A0A9J7GX10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX10#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK0" } ], "common_name": "Chinese 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"tr|A0A9J7FTK0-1|A0A9J7FTK0_CRIGR Isoform 1 of Beta-galactosidase OS=Cricetulus griseus OX=10029 GN=LOC100757754 PE=3 SV=1 CANONICAL=A0A9J7FTK0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FTK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK0/entry#A0A9J7FTK0-1", "sequence": { "sequence": "MWTFLGRPECVLYLSSALSVMALPNHNQFPRLNQTHLTPLLLLTRGEGLKVEGSQFTLEGSPFRILSGIIDYFRIPKQQWRISLRKMRACGFNTLTTHVPWNLHEPAVGQFYFTDNLDLIAFITMASEEGLWVILCPGPYIGSDLDLGGLPSWLLRDPKMKLRTTYSGFTKAMNRYFDGLVPRIAQFQYKKGGPIIAVQIENEYGSYYMDKKYMAYVQKALVSRGISELLMTADDGLNVRKGHLKNVLATVHMKNIKKQTYEDLKSIQGKSPILMMVYTTKTFDTWGALRNFGDPQMLMKDVREMFLLGFSFNFYMFHGGTNFGFIGGAQSSHGYQPVVTSYDYCALLTEAGQYTPEYRVFQEFFHSITEASTFIQPQLALGTAYSSLTVIYFMTLWEVLPLLDRPTKSAKPISMEQLPVNQRNGQSFGYTLYETTIFSGGRLFSRGHIQDRGQVFLDNNYIGVLDHYHNELLIVKNASKKTQSLSILVENQGRLTYGKDINKERKGLTGDIYLKKTPLRKFTIHSLEMKNTLIQTKLPKFPESWKSVAGQVEGPAFFLSHLRVGDPPQDTYVKVKDWGKGVIFINGQILGRYWSIGPQKALYIPSSWLHPGINEIVMFEELNGGQKIQFTSEPDLGH", "length": 638, "header": "tr|A0A9J7FTK0-1|A0A9J7FTK0_CRIGR Isoform 1 of Beta-galactosidase OS=Cricetulus griseus OX=10029 GN=LOC100757754 PE=3 SV=1 CANONICAL=A0A9J7FTK0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GX10-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK0/entry#A0A9J7GX10-1", "sequence": { "sequence": "MASEEGLWVILCPGPYIGSDLDLGGLPSWLLRDPKMKLRTTYSGFTKAMNRYFDGLVPRIAQFQYKKGGPIIAVQIENEYGSYYMDKKYMAYVQKALVSRGISELLMTADDGLNVRKGHLKNVLATVHMKNIKKQTYEDLKSIQGKSPILMMVYTTKTFDTWGALRNFGDPQMLMKDVREMFLLGFSFNFYMFHGGTNFGFIGGAQSSHGYQPVVTSYDYCALLTEAGQYTPEYRVFQEFFHSITEASTFIQPQLALGTAYSSLTVIYFMTLWEVLPLLDRPTKSAKPISMEQLPVNQRNGQSFGYTLYETTIFSGGRLFSRGHIQDRGQVFLDNNYIGVLDHYHNELLIVKNASKKTQSLSILVENQGRLTYGKDINKERKGLTGDIYLKKTPLRKFTIHSLEMKNTLIQTKLPKFPESWKSVAGQVEGPAFFLSHLRVGDPPQDTYVKVKDWGKGVIFINGQILGRYWSIGPQKALYIPSSWLHPGINEIVMFEELNGGQKIQFTSEPDLGH", "length": 514, "header": "tr|A0A9J7GX10-1|A0A9J7GX10_CRIGR Computationally mapped isoform of beta-galactosidase OS=Cricetulus griseus OX=10029 GN=LOC100757754 PE=3 SV=1 CANONICAL=A0A9J7FTK0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757754", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757754", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "beta-galactosidase activity", "id": "GO:0004565", "url": 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615869.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016818588.1. 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"id": "XP_003504872", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504872" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614091.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504872" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTU4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTU4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100760404", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTU4", "locus": {} } ], "crossref": [ { "id": "A0A9J7FTU4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FTU4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10288", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10288", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760404", "url": "https://www.ncbi.nlm.nih.gov/gene/100760404", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760404", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760404", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FTU4", "url": "https://www.orthodb.org/?gene=A0A9J7FTU4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11417", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11417", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11417:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11417:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504872", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504872", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FTU4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTU4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELPLSKLHISGTFLLLVLNLLLWEKAASIPECHTEEGGCWNPLVETFNSAINRAKNIRDLAEQMHQEFFHNEFSSKAFANLLTKMNRRDQAVLRARLYCHANSTNPPDHGTEHVNIKNKKYLKMLINYVGAWTSPLYHLTLELSAMPDAPETIISKANEIEENNKELLNDLRWILAKAYPTAHMKEKFPSWEHLPYIKSNNKANKFLAMFNLSYCLRLNIFFTVYHLRTLKCRIAGKDC", "length": 240, "header": "tr|A0A9J7FTU4-1|A0A9J7FTU4_CRIGR Isoform 1 of Prolactin-8A9-like OS=Cricetulus griseus OX=10029 GN=LOC100760404 PE=3 SV=1 CANONICAL=A0A9J7FTU4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FTU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTU4/entry#A0A9J7FTU4-1", "sequence": { "sequence": "MELPLSKLHISGTFLLLVLNLLLWEKAASIPECHTEEGGCWNPLVETFNSAINRAKNIRDLAEQMHQEFFHNEFSSKAFANLLTKMNRRDQAVLRARLYCHANSTNPPDHGTEHVNIKNKKYLKMLINYVGAWTSPLYHLTLELSAMPDAPETIISKANEIEENNKELLNDLRWILAKAYPTAHMKEKFPSWEHLPYIKSNNKANKFLAMFNLSYCLRLNIFFTVYHLRTLKCRIAGKDC", "length": 240, "header": "tr|A0A9J7FTU4-1|A0A9J7FTU4_CRIGR Isoform 1 of Prolactin-8A9-like OS=Cricetulus griseus OX=10029 GN=LOC100760404 PE=3 SV=1 CANONICAL=A0A9J7FTU4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265413", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265413" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cntnap3c", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW4", "locus": {} } ], "crossref": [ { "id": "A0A9J7FTW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FTW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] 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"length": 1199, "header": "tr|A0A9J7FTW4-1|A0A9J7FTW4_CRIGR Isoform 1 of Contactin-associated protein-like 3 isoform X3 OS=Cricetulus griseus OX=10029 GN=Cntnap3c PE=3 SV=1 CANONICAL=A0A9J7FTW4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 818, "start_aa": "Thr", "end_pos": 818, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr818", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid 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"database": "UniProtKB", "id": "A0A9J7FTW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW4" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1034, "end_pos": 1036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1189, "end_pos": 1191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, 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"https://www.ncbi.nlm.nih.gov/protein/XP_003510565" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614897.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003510565.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510565" } ] }, { "annotation": "Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6#function" }, { "database": "UniProtKB", "id": "ARBA00057606", "url": "https://www.uniprot.org/uniprotkb/ARBA00057606#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Treh", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6", "locus": {} } ], "crossref": [ { "id": "A0A9J7FTW6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FTW6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100759542", "url": "https://www.ncbi.nlm.nih.gov/gene/100759542", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008928", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008928", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759542", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759542", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYWDASD", "url": "https://omabrowser.org/oma/group/RYWDASD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FTW6", "url": "https://www.orthodb.org/?gene=A0A9J7FTW6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23403", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23403", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23403:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23403:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "32675", "url": "https://www.rhea-db.org/rhea/32675", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FTW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXF2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKVSWELHLLLLLGLGLRSQEALPPPCESQIYCHGELLHQIQMAKLYQDDKQFVDMSIATSPDEVLQSFSELAVAYNHSIPRGQLQEFVQRHFQPVGQELEPWVPEDWKDSPQFLQKISDAKLRAWAEQLHQIWKRLGKKMKPEILSYPERFSLIYSEHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVETYGHIPNGGRVYYLQRSQPPLLTLMMDLYVTHTKDVSFLQENIGTVASELDFWTVNRTITVNSGGRSYNLNRYYVPYGGPRPESYSKDADLANTVPEGDREALWTELKAGAESGWDFSSRWLVGGPNPDSLSSIRTSKMVPVDLNAFLCQAEGLMSNFYSRLGNDTEATKYRNLRSQRLAAMEALLWDEQKGAWFDYDLEKGKKNLEFYPSNLTPLWTGCFSDPSVIDKALKYLEDNQILTYQYGIPTSLRNTGQQWDLPNAWAPLQDLVIRGLAKSDSPRTREVAFQLAQNWIRTNFKVYSQTSAMYEKYDISNGGHPGGGGEYEVQEGFGWTNGLALVLLDHYGDQLTSGTQLASLGPHCLVAALLISLLLQ", "length": 579, "header": "tr|A0A9J7FTW6-1|A0A9J7FTW6_CRIGR Isoform 1 of Trehalase OS=Cricetulus griseus OX=10029 GN=Treh PE=3 SV=1 CANONICAL=A0A9J7FTW6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FTW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6/entry#A0A9J7FTW6-1", "sequence": { "sequence": "MLKVSWELHLLLLLGLGLRSQEALPPPCESQIYCHGELLHQIQMAKLYQDDKQFVDMSIATSPDEVLQSFSELAVAYNHSIPRGQLQEFVQRHFQPVGQELEPWVPEDWKDSPQFLQKISDAKLRAWAEQLHQIWKRLGKKMKPEILSYPERFSLIYSEHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVETYGHIPNGGRVYYLQRSQPPLLTLMMDLYVTHTKDVSFLQENIGTVASELDFWTVNRTITVNSGGRSYNLNRYYVPYGGPRPESYSKDADLANTVPEGDREALWTELKAGAESGWDFSSRWLVGGPNPDSLSSIRTSKMVPVDLNAFLCQAEGLMSNFYSRLGNDTEATKYRNLRSQRLAAMEALLWDEQKGAWFDYDLEKGKKNLEFYPSNLTPLWTGCFSDPSVIDKALKYLEDNQILTYQYGIPTSLRNTGQQWDLPNAWAPLQDLVIRGLAKSDSPRTREVAFQLAQNWIRTNFKVYSQTSAMYEKYDISNGGHPGGGGEYEVQEGFGWTNGLALVLLDHYGDQLTSGTQLASLGPHCLVAALLISLLLQ", "length": 579, "header": "tr|A0A9J7FTW6-1|A0A9J7FTW6_CRIGR Isoform 1 of Trehalase OS=Cricetulus griseus OX=10029 GN=Treh PE=3 SV=1 CANONICAL=A0A9J7FTW6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6/entry#A0A9J7JXF2-1", "sequence": { "sequence": "MLKVSWELHLLLLLGLGLRSQEALPPPCESQIYCHGELLHQIQMAKLYQDDKQFVDMSIATSPDEVLQSFSELAVAYNHSIPRGQLQEFVQRHFQPVGQELEPWVPEDWKDSPQFLQKISDAKLRAWAEQLHQIWKRLGKKMKPEILSYPERFSLIYSEHPFIVPGGRFVEFYYCYGHIPNGGRVYYLQRSQPPLLTLMMDLYVTHTKDVSFLQENIGTVASELDFWTVNRTITVNSGGRSYNLNRYYVPYGGPRPESYSKDADLANTVPEGDREALWTELKAGAESGWDFSSRWLVGGPNPDSLSSIRTSKMVPVDLNAFLCQAEGLMSNFYSRLGNDTEATKYRNLRSQRLAAMEALLWDEQKGAWFDYDLEKGKKNLEFYPSNLTPLWTGCFSDPSVIDKALKYLEDNQILTYQYGIPTSLRNTGQQWDLPNAWAPLQDLVIRGLAKSDSPRTREVAFQLAQNWIRTNFKVYSQTSAMYEKYDISNGGHPGGGGEYEVQEGFGWTNGLALVLLDHYGDQLTSGTQLASLGPHCLVAALLISLLLQ", "length": 548, "header": "tr|A0A9J7JXF2-1|A0A9J7JXF2_CRIGR Computationally mapped isoform of Trehalase OS=Cricetulus griseus OX=10029 GN=Treh PE=3 SV=1 CANONICAL=A0A9J7FTW6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759542", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759542", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1B8N4-1", "protein_name": "Trehalase", "gene_name": "TREH", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQGRTWGLRLLLLLGLRLGSQEALPPPCGSQIYCHGELLRQVQMAKLYQDDKQFVDMPLSSAPDQVLRHFRELAQTHNLSIPRQELQMFVQEHFRAVGQELQPWTPEDWRDSPQFLQKILDPRLRAWAGQLHQLWKKLGKKVKPEVLSHPEQFSLIYSRHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMPETVKGMLQNFLDLVQTYGHVPNGARVYYLQRSQPPLLTLMMDRYVAHTNDTTFLRDHIETLASELDFWTKNRSISVSSGGKSYILNHYEVPYGGPRPESYSKDAELAATLLEGNRDTLLAELKASAESGWDFSSRWLVGGPNPSSLSSIRTSKLVPVDLNAFLCQAEGLMSNFYSRLGNDSEAAKYRNLRAERMAALKDVLWDEDKGVWFDYDLENEKKNLEFYPSNFAPLWAGCFSDPDDVDKALKYLEDSRILTYQYGIPTSLQKTGQQWDFPNAWAPLQDLVIRGLAKSPSAKAQEVAFQLAQNWIRTNFDVYSKKSAMYEKYDISNGGQPGGGGEYEVQEGFGWTNGVALMLLDRYGDRLSSGAQTALLAPHCLAAALLLSLLPQ", "length": 579 }, "evidence": [ { "id": "A0A9J7FTW6", "url": "https://omabrowser.org/oma/group/A0A9J7FTW6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3V7Q9-1", "protein_name": "Trehalase", "gene_name": "Treh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTWELHLLLLLGLGLSSQEALPPPCESQIYCHGELLHQVQMAQLYQDDKQFVDMSLATSPDEVLQKFSELAVAHNHSIPREELQNFVQSYFQPVGQELQPWTPEDWKDSPQFLQKISDSRLRVWAEELHKIWKKLGKKMKAEVLSHPERSSLIYSEHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVKTYGHIPNGGRVYYLQRSHPPLLTLMMERYVAHTNDVAFLRENIGTLALELEFWTVNRTVSVGSGGQSYILNRYYVPYGGPRPESYSKDEELAKTVPEGDRETLWAELKAGAESGWDFSSRWLVGGPDPDLLSSIRTSKMVPADLNAFLCQAEELMSNFYSRLGNDTEAKRYRNLRAQRLAAMEAILWDEQKGAWFDYDLEKGKKNLEFYPSNLTPLWAGCFSDPSVADRALKYLEDNKILTYQYGIPTSLRNTGQQWDFPNAWAPLQDLVIRGLAKSASPRTQEVAFQLAQNWIKTNFKVYSQKSAMYEKYDISNGGHPGGGGEYEVQEGFGWTNGLALMLLDRYGDQLTSGTQLASLGPHCLVTALLLSLLLQ", "length": 576 }, "evidence": [ { "id": "A0A9J7FTW6", "url": "https://omabrowser.org/oma/group/A0A9J7FTW6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LIR5-1", "protein_name": "Trehalase", "gene_name": "TREH", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQRRTWGLHLLLLLGLGLGSWEALPPPCESQIYCHGELLRQVQMARLYQDDKQFVDMPLSVAPDQVLQRFSELAQAHNFSIPQQELQDFIREHFQAVGQELQPWTPEDWKDSPQFLQKILDPKLRAWAGQLHQLWKKLGKKVKPEVLSHPERFSLIYSGHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMPGTVKGMLQNFLDLVQTYGHVPNGARVYYLQRSQPPLLSLMMERYVTQANDTAFLRDNLETLALELDFWTKNRSISVSSGGKSYVLNRYHVPYGGPRPESYSKDAELAATLSEGDHEALWAELKAGAESGWDFSSRWFVGGPNPDSLSSIRTSKLVPVDLNAFLCQAEELMSNFYSRLGNDSQAEKYRNLRAQRMAAMKDILWDEEKGAWFDYDLENGKKNLEFYPSNLAPLWAGCFSDPGDVDKALKYLEDSQILTYHYGIPTSLRKTGQQWDFPNAWAPLQDLVIRGLAKSPSARAQEVAFQLAQNWIRTNFDVYSRRSAMYEKYDISNGGQPGGGGEYEVQEGFGWTNGVVLMLLDRYGDRLSSGTQTVFLEPHCLTAALLLGLMLSLLPQ", "length": 583 }, "evidence": [ { "id": "A0A9J7FTW6", "url": "https://omabrowser.org/oma/group/A0A9J7FTW6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O43280-1", "protein_name": "Trehalase", "gene_name": "TREH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGRTWELCLLLLLGLGLGSQEALPPPCESEIYCHGELLNQVQMAKLYQDDKQFVDMPLSIAPEQVLQTFTELSRDHNHSIPREQLQAFVHEHFQAKGQELQPWTPADWKDSPQFLQKISDAKLRAWAGQLHQLWKKLGKKMKPEVLSHPERFSLIYSEHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMAETVKGMLQNFLDLVKTYGHVPNGGRVYYLQRSQPPLLTLMMDCYLTHTNDTAFLQENIETLALELDFWTKNRTVSVSLEGKNYLLNRYYVPYGGPRPESYSKDVELADTLPEGDREALWAELKAGAESGWDFSSRWLIGGPNPNSLSGIRTSKLVPVDLNAFLCQAEELMSNFYSRLGNDSQATKYRILRSQRLAALNTVLWDEQTGAWFDYDLEKKKKNREFYPSNLTPLWAGCFSDPGVADKALKYLEDNRILTYQYGIPTSLQKTGQQWDFPNAWAPLQDLVIRGLAKAPLRRAQEVAFQLAQNWIRTNFDVYSQKSAMYEKYDVSNGGQPGGGGEYEVQEGFGWTNGVVLMLLDRYGDRLTSGAKLAFLEPHCLAATLLPSLLLSLLPW", "length": 583 }, "evidence": [ { "id": "A0A9J7FTW6", "url": "https://omabrowser.org/oma/group/A0A9J7FTW6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54QZ5-1", "protein_name": "Trehalase", "gene_name": "treh", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFLNKKIQKILFICILSFLIVNLTKSEISEVKDVSKFLSVGGGGTGGCQHPIYCNGTLLKTIQLTQVFNDSKTFVDMPMRTSIENVNELFNQLLLNTSKNGGPNKEELAAFLSENFYPAGYEVEPVTPVDWVPNPSFLDEITDPNLVDFARSIHGKWLELTRVFNTSGLCDGCYSSIPVNNPFVIAGSRFREFYYWDSYWIIQGLLVSDMTTTAKGMLRNFGDMITEFGFIPNGGRIYYLNRSQPPLFTQMVNKYFEATNGSDIEFLQEILPILDQEYQWWMTHRTTELTNGETGESVILNLYNVSNNSPRPESYYEDFTDAQSFSSVEEKDYFYSSIASGAESGWDFSSRWMSPSDNTNLTTIQTVDVVPVDLNSILYLNEKILSSFHRTLGNNSMAVYYQAQSESRVDAMQQVFFNEDTYQWNDYNLKTSTNNEAWYTSNILPLFADIQSSIDMDNQEIDLIFKSLANVLIAYPGGVPTSLISAQSLQWDGLNVWPPLQYWIIESIMTPNTTFSNMIGKNLIDRWITTNFCGWNSTLESEGGMMFEKYNANYIGVPGGGGEYVVQNGFGWTNGVDLYLLKKYGKSITLNSC", "length": 594 }, "evidence": [ { "id": "A0A9J7FTW6", "url": "https://omabrowser.org/oma/group/A0A9J7FTW6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9JLT2-1", "protein_name": "Trehalase", "gene_name": "Treh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTWELHLLLLLGLGLRSQEALPPPCESQIYCHGELLHQVQMAQLYQDDKQFVDMSLATSPDEVLQKFSELATVHNHSIPKEQLQEFVQSHFQPVGQELQSWTPEDWKDSPQFLQKISDANLRVWAEELHKIWKKLGKKMKAEVLSYPERSSLIYSKHPFIVPGGRFVEFYYWDSYWVMEGLLLSEMASTVKGMLQNFLDLVKTYGHIPNGGRIYYLQRSQPPLLTLMMDRYVAHTKDVAFLQENIGTLASELDFWTVNRTVSVVSGGQSYVLNRYYVPYGGPRPESYRKDAELANSVPEGDRETLWAELKAGAESGWDFSSRWLVGGPDPDLLSSIRTSKMVPADLNAFLCQAEELMSNFYSRLGNDTEATKYRNLRAQRLAAMEAVLWDEQKGAWFDYDLEKGKKNLEFYPSNLSPLWAGCFSDPSVADKALKYLEDSKILTYQYGIPTSLRNTGQQWDFPNAWAPLQDLVIRGLAKSASPRTQEVAFQLAQNWIKTNFKVYSQKSAMFEKYDISNGGHPGGGGEYEVQEGFGWTNGLALMLLDRYGDQLTSGTQLASLGPHCLVAALLLSLLLQ", "length": 576 }, "evidence": [ { "id": "A0A9J7FTW6", "url": "https://omabrowser.org/oma/group/A0A9J7FTW6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SU50-1", "protein_name": "Trehalase", "gene_name": "TRE1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKSYKLNNPNLLISTHTHNKLFLSSSPFNLLFSFPSFIYLKQQRSLFFFFFFFLCFSFTTSMLDSDTDTDSGPVVATTKLVTFLQRVQHTALRSYPKKQTPDPKSYIDLSLKRPYSLSTIESAFDDLTSESHDQPVPVETLEKFVKEYFDGAGEDLLHHEPVDFVSDPSGFLSNVENEEVREWAREVHGLWRNLSCRVSDSVRESADRHTLLPLPEPVIIPGSRFREVYYWDSYWVIKGLMTSQMFTTAKGLVTNLMSLVETYGYALNGARAYYTNRSQPPLLSSMVYEIYNVTKDEELVRKAIPLLLKEYEFWNSGKHKVVIRDANGYDHVLSRYYAMWNKPRPESSVFDEESASGFSTMLEKQRFHRDIATAAESGCDFSTRWMRDPPNFTTMATTSVVPVDLNVFLLKMELDIAFMMKVSGDQNGSDRFVKASKAREKAFQTVFWNEKAGQWLDYWLSSSGEESETWKAENQNTNVFASNFAPIWINSINSDENLVKKVVTALKNSGLIAPAGILTSLTNSGQQWDSPNGWAPQQEMIVTGLGRSSVKEAKEMAEDIARRWIKSNYLVYKKSGTIHEKLKVTELGEYGGGGEYMPQTGFGWSNGVILAFLEEYGWPSHLSIEA", "length": 626 }, "evidence": [ { "id": "A0A9J7FTW6", "url": "https://omabrowser.org/oma/group/A0A9J7FTW6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9W2M2-1", "protein_name": "Trehalase", "gene_name": "Treh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKLPTISLLLVSWSCLVALSQAKTYSLPDLTTDYNNAIPVDEEEAQDPFASCKIYCEGNLLHTIQTAVPKLFADSKTFVDMKLNNSPDKTLEDFNAMMEAKNQTPSSEDLKQFVDKYFSAPGTELEKWTPTDWKENPSFLDLISDPDLKQWGVELNSIWKDLGRKMKDEVSKNPEYYSIIPVPNPVIVPGGRFIEFYYWDSYWIIRGLLYSQMFDTARGMIENFFSIVNRFGFIPNGGRVYYHGRSQPPLLTGMVKSYVDFTNDDKFAIDALDTLEHEFEFFVNNHNVTVKNHSLCVYRDSSSGPRPESYREDVETGEEFPTDEAKELHYSELKAGAESGMDFSSRWFISPTGTNDGNRSALSTTSIVPVDLNAYLYWNAKLIAEFHSKAGNTKKVTEYETKAEKLLLGIQEVLWNEEAGVWLDYDMINQKPRDYYTPTNLSPLWVKAFNISESEKISASVMAYIERNKLDSFPGGVPNTLSYTGEQWDAPNVWAPMQYILVEGLNNLNTPEAKNMSLKWATRWVKTNFAAFSKDRHMYEKYNADEFGVGGGGGEYEVQTGFGWSNGVIIEWLSKHGRDISIGSGCGCLAGEKRQ", "length": 596 }, "evidence": [ { "id": "A0A9J7FTW6", "url": "https://omabrowser.org/oma/group/A0A9J7FTW6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "alpha,alpha-trehalase activity", "id": "GO:0004555", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004555", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "trehalose catabolic process", "id": "GO:0005993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005993", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTW6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "32675", "name": "", "equation": "alpha,alpha-trehalose + H2O = 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"A0A9J7FTY2", "uniprot_id": "A0A9J7FTY2_CRIGR", "mass": { "chemical_mass": 80285.0, "monoisotopic_mass": 80285.0 }, "refseq": { "ac": "XP_027268316", "name": "NF-kappa-B inhibitor zeta isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268316" }, "gene_names": [ { "name": "Nfkbiz", "type": "recommended", "evidence": [ { "id": "A0A9J7FTY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2" } ] }, { "name": "Nfkbiz", "type": "synonym", "evidence": [ { "id": "XP_027268316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268316" } ] } ], "protein_names": [ { "name": "NF-kappa-B inhibitor zeta", "type": "recommended", "evidence": [ { "id": "A0A9J7FTY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2/entry#names_and_taxonomy" } ] }, { "name": "I-kappa-B-zeta", "type": "synonym", "evidence": [ { "id": "A0A9J7FTY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2/entry#names_and_taxonomy" } ] }, { "name": "IL-1 inducible nuclear ankyrin-repeat protein", "type": "synonym", "evidence": [ { "id": "A0A9J7FTY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2/entry#names_and_taxonomy" } ] }, { "name": "Molecule possessing ankyrin repeats induced by lipopolysaccharide", "type": "synonym", "evidence": [ { "id": "A0A9J7FTY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2/entry#names_and_taxonomy" } ] }, { "name": "NF-kappa-B inhibitor zeta isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027268316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268316" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268316" } ] }, { "annotation": "Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Also seems to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR).", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9B0", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B0#function" }, { "database": "UniProtKB", "id": "ARBA00094480", "url": "https://www.uniprot.org/uniprotkb/ARBA00094480#function" }, { "database": "UniProtKB", "id": "A0A9J7FTY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2#function" }, { "database": "UniProtKB", "id": "A0A9J7FVJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVJ8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nfkbiz", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2", "locus": {} } ], "crossref": [ { "id": "A0A9J7FTY2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FTY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100759240", "url": "https://www.ncbi.nlm.nih.gov/gene/100759240", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759240", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759240", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FTY2", "url": "https://www.orthodb.org/?gene=A0A9J7FTY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24124", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24124", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24124:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24124:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268316", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I9B0", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I9B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVJ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIVDKLLDDSRGGEGLLDAAGDCGLMTSPLNLAYFYGASPPSAPGAGDAGYLSAVPSAPGSPGSDSSDFSSTSSVSSCGAVESRPRGGARAERPQVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKTSSLSVDEFKAQSVNIEQLTEVKSTVSAVGKRKGTDPLSDGPVCKRPALLSTHFVTSPQTPTSGESMEDVRPNESKLDSSADLLQNIINIKNECSSVSLNTVQVSWMSPAVPQNSPRDQCQDFHGGQVFSPPQKYQPFQVSGSPQMMDQASMYQYLPQTQSMQQQPQPQQQQQQQQQQQQQQQQQNYPHNPALQFSSCSRTSQSPKYESNLFDSQDPQFCTSQSFVSLLSGHGESENIAVPLQPSSSIPQQNETHLQSFSLMPNNACEAGRVHDAGSPSLGTSLSLQNIMGSPMNTTQLGKSFFQWQVEQEESKLANISQDQFLYKDSDGDTFLHIAVAQGRRALSYVLARKMNAFHMLDVKEHNGQSAFQVAVAANQHLIVQDLVNLGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVRSNQFVDLEATNYDGLTPLHCAVLAHNAVVHELQRNQQPHSPEVQDLLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRVTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY", "length": 736, "header": "tr|A0A9J7FTY2-1|A0A9J7FTY2_CRIGR Isoform 1 of NF-kappa-B inhibitor zeta OS=Cricetulus griseus OX=10029 GN=Nfkbiz PE=4 SV=1 CANONICAL=A0A9J7FTY2-1" }, "isoforms": [ { "isoform_ac": "A0A061I9B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2/entry#A0A061I9B0-1", "sequence": { "sequence": "MGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKTSSLSVDEFKAQSVNIEQLTEVKSTVSAVGKRKGTDPLSDGPVCKRPALLSTHFVTSPQTPTSGESMEDVRPNESKLDSSADLLQNIINIKNECSSVSLNTVQVSWMSPAVPQNSPRDQCQDFHGGQVFSPPQKYQPFQVSGSPQMMDQASMYQYLPQTQSMQQQPQPQQQQQQQQQQQQQQQQQNYPHNPALQFSSCSRTSQSPKYESNLFDSQDPQFCTSQSFVSLLSGHGESENIAVPLQPSSSIPQQNETHLQSFSLMPNNACEAGRVHDAGSPSLGTSLSLQNIMGSPMNTTQLGKSFFQWQVEQEESKLANISQDQFLYKDSDGDTFLHIAVAQGRRALSYVLARKMNAFHMLDVKEHNGQSAFQVAVAANQHLIVQDLVNLGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVRSNQFVDLEATNYDGLTPLHCAVLAHNAVVHELQRNQQPHSPEVQDLLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRVTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY", "length": 637, "header": "tr|A0A061I9B0-1|A0A061I9B0_CRIGR Computationally mapped isoform of NF-kappa-B inhibitor zeta OS=Cricetulus griseus OX=10029 GN=Nfkbiz PE=4 SV=1 CANONICAL=A0A9J7FTY2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2/entry#A0A9J7FTY2-1", "sequence": { "sequence": "MIVDKLLDDSRGGEGLLDAAGDCGLMTSPLNLAYFYGASPPSAPGAGDAGYLSAVPSAPGSPGSDSSDFSSTSSVSSCGAVESRPRGGARAERPQVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKTSSLSVDEFKAQSVNIEQLTEVKSTVSAVGKRKGTDPLSDGPVCKRPALLSTHFVTSPQTPTSGESMEDVRPNESKLDSSADLLQNIINIKNECSSVSLNTVQVSWMSPAVPQNSPRDQCQDFHGGQVFSPPQKYQPFQVSGSPQMMDQASMYQYLPQTQSMQQQPQPQQQQQQQQQQQQQQQQQNYPHNPALQFSSCSRTSQSPKYESNLFDSQDPQFCTSQSFVSLLSGHGESENIAVPLQPSSSIPQQNETHLQSFSLMPNNACEAGRVHDAGSPSLGTSLSLQNIMGSPMNTTQLGKSFFQWQVEQEESKLANISQDQFLYKDSDGDTFLHIAVAQGRRALSYVLARKMNAFHMLDVKEHNGQSAFQVAVAANQHLIVQDLVNLGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVRSNQFVDLEATNYDGLTPLHCAVLAHNAVVHELQRNQQPHSPEVQDLLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRVTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY", "length": 736, "header": "tr|A0A9J7FTY2-1|A0A9J7FTY2_CRIGR Isoform 1 of NF-kappa-B inhibitor zeta OS=Cricetulus griseus OX=10029 GN=Nfkbiz PE=4 SV=1 CANONICAL=A0A9J7FTY2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2/entry#A0A9J7FVJ8-1", "sequence": { "sequence": "MIVDKLLDDSRGGEGLLDAAGDCGLMTSPLNLAYFYGASPPSAPGAGDAGYLSAVPSAPGSPGSDSSDFSSTSSVSSCGAVESRPRGGARAERPQVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKTSSLSVDEFKAQSVNIEQLTVKSTVSAVGKRKGTDPLSDGPVCKRPALLSTHFVTSPQTPTSGESMEDVRPNESKLDSSADLLQNIINIKNECSSVSLNTVQVSWMSPAVPQNSPRDQCQDFHGGQVFSPPQKYQPFQVSGSPQMMDQASMYQYLPQTQSMQQQPQPQQQQQQQQQQQQQQQQQNYPHNPALQFSSCSRTSQSPKYESNLFDSQDPQFCTSQSFVSLLSGHGESENIAVPLQPSSSIPQQNETHLQSFSLMPNNACEAGRVHDAGSPSLGTSLSLQNIMGSPMNTTQLGKSFFQWQVEQEESKLANISQDQFLYKDSDGDTFLHIAVAQGRRALSYVLARKMNAFHMLDVKEHNGQSAFQVAVAANQHLIVQDLVNLGAQVNTTDCWGRTPLHVCAEKGHSQVLQAIQKGAVRSNQFVDLEATNYDGLTPLHCAVLAHNAVVHELQRNQQPHSPEVQDLLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLSFVNAKAYNGNTALHVAASLQYRVTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGEQIRRILKGKSIQQRAPPY", "length": 735, "header": "tr|A0A9J7FVJ8-1|A0A9J7FVJ8_CRIGR Computationally mapped isoform of NF-kappa-B inhibitor zeta OS=Cricetulus griseus OX=10029 GN=Nfkbiz PE=4 SV=1 CANONICAL=A0A9J7FTY2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759240", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759240", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTY2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTY2" } ], "pmid": "" }, { "name": "POU domain binding", "id": "GO:0070974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070974", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTY2", "url": 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266475", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266475" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Il17c", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ0", "locus": {} } ], "crossref": [ { "id": "A0A9J7FTZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FTZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100767127", "url": "https://www.ncbi.nlm.nih.gov/gene/100767127", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767127", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767127", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FTZ0", "url": "https://www.orthodb.org/?gene=A0A9J7FTZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF06083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266475", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266475", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FTZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSHVPGQHVGLLPPETLDSTQSHQFNALLSSEFICTSKAEVETGAARVNQTPSKLITSWLKPSSANPFVVQPGINCCYPGPQFSCLGSGCLLLLAWLPTGMTHQDLQFQGKARSHGTLRCYSAEELSHGQAPPHLLTRSARWEQALPVALVSTLEATGHRRQHERPQAGTQCPVLRPEEVLEADTHQRSISPWKYRIDTDKNRYPQKLAVAECLCRGCINAKTGRETAALNSVQLLQSLLVLRRQPCSQDGTANPTPGSFTFHTEFIRVPVGCTCVLPRSAQ", "length": 283, "header": "tr|A0A9J7FTZ0-1|A0A9J7FTZ0_CRIGR Isoform 1 of Interleukin-17C OS=Cricetulus griseus OX=10029 GN=Il17c PE=3 SV=1 CANONICAL=A0A9J7FTZ0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FTZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ0/entry#A0A9J7FTZ0-1", "sequence": { "sequence": "MKSHVPGQHVGLLPPETLDSTQSHQFNALLSSEFICTSKAEVETGAARVNQTPSKLITSWLKPSSANPFVVQPGINCCYPGPQFSCLGSGCLLLLAWLPTGMTHQDLQFQGKARSHGTLRCYSAEELSHGQAPPHLLTRSARWEQALPVALVSTLEATGHRRQHERPQAGTQCPVLRPEEVLEADTHQRSISPWKYRIDTDKNRYPQKLAVAECLCRGCINAKTGRETAALNSVQLLQSLLVLRRQPCSQDGTANPTPGSFTFHTEFIRVPVGCTCVLPRSAQ", "length": 283, "header": "tr|A0A9J7FTZ0-1|A0A9J7FTZ0_CRIGR Isoform 1 of Interleukin-17C OS=Cricetulus griseus OX=10029 GN=Il17c PE=3 SV=1 CANONICAL=A0A9J7FTZ0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 257, "start_aa": "Thr", "end_pos": 257, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr257", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767127", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767127", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 257 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FTZ9-1", "uniprot_ac": "A0A9J7FTZ9", "uniprot_id": "A0A9J7FTZ9_CRIGR", "mass": { "chemical_mass": 69160.0, "monoisotopic_mass": 69160.0 }, "refseq": { "ac": "XP_007645010", "name": "GPI 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"https://www.ncbi.nlm.nih.gov/protein/XP_007645010" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613582.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645010" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pigb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9", "locus": {} } ], "crossref": [ { "id": "100768002", "url": "https://www.ncbi.nlm.nih.gov/gene/100768002", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768002", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768002", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHMVFNN", "url": "https://omabrowser.org/oma/group/HHMVFNN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FTZ9", "url": "https://www.orthodb.org/?gene=A0A9J7FTZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GYF2", "url": "https://www.orthodb.org/?gene=A0A9J7GYF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22760:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22760:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645010", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "61000", "url": "https://www.rhea-db.org/rhea/61000", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "61004", "url": "https://www.rhea-db.org/rhea/61004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MLW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MLW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MLW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MLW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GW35", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GW35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GW35-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GW35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYF2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPEAGDHGPALCSLHSRSGEMKLRKRKSTLYVNTQEKRSRRRDLLGENIYLVLFTIALRIFNCFLVQTSFVPDEYWQSLEVAHHMVFRYGYLTWEWTERLRGYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQVGNQQVARWVFFCQLCSWFTWYCCTRTLTNTMETALTAIALFYYPLEGSRSMNSVKYSLLVALACIVRPTALIPWVPLLFRHFYREQRKLCLVLHHLLPVGFITFSLSLIIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPVVLGTHLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGPGNRSKVGLWSYAYENYTILRATKKTYVWWDLTGYNQTCGAAPYKKIMDLSPGYSLAHLKAWRKAAVSFLLLSNVLLALYTGLVHQRGTLDVMNHIQQACPRGPDPASVSVLIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEADMFYLNPLSWLQQEFRSNASLPTYLVTFSVLEKEIYAFLTSGSYERTAIFFHTHWPEGRIGSHVHVYERRLTSRVNTGGN", "length": 595, "header": "tr|A0A9J7FTZ9-1|A0A9J7FTZ9_CRIGR Isoform 1 of Mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Pigb PE=3 SV=1 CANONICAL=A0A9J7FTZ9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MLW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9/entry#A0A8C2MLW5-1", "sequence": { "sequence": "MEPEAGDHGPALCSLHSRSGEMKLRKRKSTLYVNTQEKRSRRRDLLGENIYLVLFTIALRIFNCFLVQTSFVPDEYWQSLEVAHHMVFRYGYLTWEWTERLRGYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQVGNQQVARWVFFCQLCSWFTWYCCTRTLTNTMETALTAIALFYYPLEGSRSMNSVKYSLLVALACIVRPTALIPWVPLLFRHFYREQRKLCLVLHHLLPVGFITFSLSLIIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPVVLGTHLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSLAHLKAWRKAAVSFLLLSNVLLALYTGLVHQRGTLDVMNHIQQACPRGPDPASVSVLIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEADMFYLNPLSWLQQEFRSNASLPTYLVTFSVLEKEIYAFLTSGSYERTAIFFHTHWPEGRIGSHVHVYERRLTSRVNTGGN", "length": 542, "header": "tr|A0A8C2MLW5-1|A0A8C2MLW5_CRIGR Computationally mapped isoform of Mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Pigb PE=3 SV=1 CANONICAL=A0A9J7FTZ9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9/entry#A0A9J7FTZ9-1", "sequence": { "sequence": "MEPEAGDHGPALCSLHSRSGEMKLRKRKSTLYVNTQEKRSRRRDLLGENIYLVLFTIALRIFNCFLVQTSFVPDEYWQSLEVAHHMVFRYGYLTWEWTERLRGYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQVGNQQVARWVFFCQLCSWFTWYCCTRTLTNTMETALTAIALFYYPLEGSRSMNSVKYSLLVALACIVRPTALIPWVPLLFRHFYREQRKLCLVLHHLLPVGFITFSLSLIIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPVVLGTHLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGPGNRSKVGLWSYAYENYTILRATKKTYVWWDLTGYNQTCGAAPYKKIMDLSPGYSLAHLKAWRKAAVSFLLLSNVLLALYTGLVHQRGTLDVMNHIQQACPRGPDPASVSVLIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEADMFYLNPLSWLQQEFRSNASLPTYLVTFSVLEKEIYAFLTSGSYERTAIFFHTHWPEGRIGSHVHVYERRLTSRVNTGGN", "length": 595, "header": "tr|A0A9J7FTZ9-1|A0A9J7FTZ9_CRIGR Isoform 1 of Mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Pigb PE=3 SV=1 CANONICAL=A0A9J7FTZ9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GW35-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9/entry#A0A9J7GW35-1", "sequence": { "sequence": "MKQVGNQQVARWVFFCQLCSWFTWYCCTRTLTNTMETALTAIALFYYPLEGSRSMNSVKYSLLVALACIVRPTALIPWVPLLFRHFYREQRKLCLVLHHLLPVGFITFSLSLIIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPVVLGTHLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGPGNRSKVGLWSYAYENYTILRATKKTYVWWDLTGYNQTCGAAPYKKIMDLSPGYSLAHLKAWRKAAVSFLLLSNVLLALYTGLVHQRGTLDVMNHIQQACPRGPDPASVSVLIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEADMFYLNPLSWLQQEFRSNASLPTYLVTFSVLEKEIYAFLTSGSYERTAIFFHTHWPEGRIGSHVHVYERRLTSRVNTGGN", "length": 445, "header": "tr|A0A9J7GW35-1|A0A9J7GW35_CRIGR Computationally mapped isoform of Mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Pigb PE=3 SV=1 CANONICAL=A0A9J7FTZ9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9/entry#A0A9J7GYF2-1", "sequence": { "sequence": "MVFRYGYLTWEWTERLRGYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQVGNQQVARWVFFCQLCSWFTWYCCTRTLTNTMETALTAIALFYYPLEGSRSMNSVKYSLLVALACIVRPTALIPWVPLLFRHFYREQRKLCLVLHHLLPVGFITFSLSLIIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPVVLGTHLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGPGNRSKVGLWSYAYENYTILRATKKTYVWWDLTGYNQTCGAAPYKKIMDLSPGYSLAHLKAWRKAAVSFLLLSNVLLALYTGLVHQRGTLDVMNHIQQACPRGPDPASVSVLIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEADMFYLNPLSWLQQEFRSNASLPTYLVTFSVLEKEIYAFLTSGSYERTAIFFHTHWPEGRIGSHVHVYERRLTSRVNTGGN", "length": 510, "header": "tr|A0A9J7GYF2-1|A0A9J7GYF2_CRIGR Computationally mapped isoform of Mannosyltransferase OS=Cricetulus griseus OX=10029 GN=Pigb PE=3 SV=1 CANONICAL=A0A9J7FTZ9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768002", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768002", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZQB9-1", "protein_name": "Mannosyltransferase", "gene_name": "PIGB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEREGGLFFRGFQNRSHGKIKLRKRKSTLYLSPQERTGSCRDLLGENIYLVLFTIALRICNCFLVQTSFVPDEYWQSLEVAHHMVFNYGYLTWEWTERLRGYTYPLIFASIYKILHLLGKDSVQLLIWIPRLSQALLSAIADLRLYSLMKQLENQQVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAVIIRPTAVIPWIPLLFRHFWQEQKKLDLILHKFLPVGFVTLSLSLIIDRIFFGQWTLVQYNFLKFNVLQNLGSFYGSHPWHWYFSQGFPAVLGTHLPFFIHGCFLTPKRYRIFLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLNSLKTWKKAALSFLFLSNTLLALYTGLVHQRGTLDVMTNIQELCYNNPNISKASVFMMMPCHSTPYYSHVHYPLPMRFLQCPPDLTGKSDYLVEADIFYLNPLKWLYREFHNDSTLPTHLIIFNVLEKEISPFLISHNYERTAVFFHTHFPEHWTGNHIYVYERKLKGKLNQR", "length": 538 }, "evidence": [ { "id": "A0A9J7FTZ9", "url": "https://omabrowser.org/oma/group/A0A9J7FTZ9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZYY8-1", "protein_name": "Mannosyltransferase", "gene_name": "Pigb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPETRDHSTAFRNLHSSSGEMKLRKRKSTQYVIAQEKRSRRRDLLGENTYLVLFTIALRIFNCFLVQTSFVPDEYWQSLEVAHHMVFGYGYLTWEWTERLRGYTYPLIFASIYKILHLLGKDSVQLLIWIPRLGQALLSAVADLRLYSLTKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETALTAVALFYYPLEGSRSKNSVKYSLLVALACVVRPTALIPWVPLLFRHLYQEQRKLHLTLHHFLPVGFITFSLSLIIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPVVLGTHLPFFIHGCFLAPRRLNILLLAVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSLAHLKAWRKAALSFLLLSNVLLALYTGLVHQRGTLDVMSHIQKVCPRGPDPAPASVFIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEADTFYLNPLGWLQQEFHSNVSLPTHLVTFNVLEKEIHAFLTSGNYERTATFFHTHWPERRTGSHIHVYERRLTSRVSTGGN", "length": 542 }, "evidence": [ { "id": "A0A9J7FTZ9", "url": "https://omabrowser.org/oma/group/A0A9J7FTZ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LZA0-1", "protein_name": "GPI alpha-1,2-mannosyltransferase 3", "gene_name": "PIGB", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MERDDGGGGGLFFRGLQNRSHEKTKLRTRKSTLYLSPQKSTGRCGDLGENIYLVLFIIALRICNCFLVQTSFVPDEYWQSLEVAHRMVFNYGYLTWEWTERLRGYTYPLIFASIYKILHLLGKDSVHLLIWIPRLAQALLSAIADLRLYSLMKQLENQQVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVIPWIPLLFRHFWQEQRKLDLILHQFLPVGFVTLSLSLIIDRIFFGQWTLVQYNFLKFNVLQDLGSFYGSHPWHWYFSQGFPAVLGTHLPFFIHGCFLAPKRYRIFLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLNNLKTWKKPALSFLFLSNMLLALYTGLVHQRGTLDVMTNIQELSYNNTNVSSASVLMMMPCHSTPYYSHVHYPLPMRFLQCPPDLTGKTDYLVEADMFYLNPLKWLYMEFQNDSQLPTHLIMFSVLEEEISPFLISNNYERTAVFFHTHFPESRTGSHIYVYERKLKGKLNQR", "length": 541 }, "evidence": [ { "id": "A0A9J7FTZ9", "url": "https://omabrowser.org/oma/group/A0A9J7FTZ9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54PM5-1", "protein_name": "Mannosyltransferase", "gene_name": "pigB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIIKLFNYITSNQKILFLSLVLYRCINSLLINTFFDPDEYWQSLEVAHKLVFGYGYLTWEWSEGLRSFIHPLIFVYLFKFLKFLNLDSTFFIIIGPKLLSGFLAAIGDLYLYKLTLSIFKSKESAKWALICQLISWYMFVCIVRTYSNSIETILFIISLYYFPINNDENTINSKPKISIALTTFAFLIRPTTAIMWLYILPLHIFINLKSIKKIFNFLIFDCLFIGLLCLFIGCFIDYIYYERFVFLPYNFLYFNVLKNISSFYGTHPFHWYWSQGLPAIGFTILPLFLLSIRSLWIKKSDRFKLHLAWCALFTVGFYSLLAHKEFRFILPILPIIMMYSGYYISTFTQLKTTTTTKESKESKESYDPKSKPNISTTLISPPKLIILLLLLNIPMSVFFSNFHQRSPIDIMHYINSDIVPKIKDNGTISVDLLMSCHATPFQSYIHNENLILTLLECPPPLNENSPIDEKSLFYKDPLNFMNTQYKHIESNNSNKNSKNLKALPNYFIVEDELLDRLEPWLLKNSYRKEYHLKKPLDITSSTVFIRV", "length": 547 }, "evidence": [ { "id": "A0A9J7FTZ9", "url": "https://omabrowser.org/oma/group/A0A9J7FTZ9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q92521-1", "protein_name": "GPI alpha-1,2-mannosyltransferase 3", "gene_name": "PIGB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRPLSKCGMEPGGGDASLTLHGLQNRSHGKIKLRKRKSTLYFNTQEKSARRRGDLLGENIYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVFYLNPLNWLHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHTHLPEGRIGSHIYVYERKLKGKFNMKMKF", "length": 554 }, "evidence": [ { "id": "A0A9J7FTZ9", "url": "https://omabrowser.org/oma/group/A0A9J7FTZ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q94A15-1", "protein_name": "Mannosyltransferase APTG1", "gene_name": "APTG1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVVYVVNHAFP", "length": 548 }, "evidence": [ { "id": "A0A9J7FTZ9", "url": "https://omabrowser.org/oma/group/A0A9J7FTZ9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JJQ0-1", "protein_name": "GPI alpha-1,2-mannosyltransferase 3", "gene_name": "Pigb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESQAADYNPASRNLHGSSGEMKLRRRKSRQYVSAQEKRSPRRGLLGENTYLVLFTIALRILNCFLVQTSFVPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTYPLIFASIYKVLHLLGKDSVQFLIWIPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTALALFYYPLEGSRSVNSVKYSLLVALACVVRPTALIPWVPLLFRHFYQEQRKLHLTLHHFLPVGFITFSLSLIIDRIFFGQWTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSLAHLKTWRKAALSFLLLSNVPLAFYTGLVHQRGTLDVMNHIQKVCPRGPDPASASVFIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEADMFYLNPLRWLQQEFHSNASLPTHLVTFNVLEKEINTFLTSGNYERAATFFHTHWPERRTGSHIHVYERRLPGRVNTGGN", "length": 542 }, "evidence": [ { "id": "A0A9J7FTZ9", "url": "https://omabrowser.org/oma/group/A0A9J7FTZ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZM5-1", "protein_name": "GPI mannosyltransferase 3", "gene_name": "PIG-B", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIAGLYKILALLQLDSAHLLVVLPRIVQALLSAYSDYRFFVWTGKRKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENISVFLRNYRLLHRIEHAEVTRLEGSQALVDQWSEALGAQSPNLASLLQNRQSRTGRSILVYQRLKKGEENAFNRGPDSGQHEPDVHDHPPLEDLVLANENENLFN", "length": 561 }, "evidence": [ { "id": "A0A9J7FTZ9", "url": "https://omabrowser.org/oma/group/A0A9J7FTZ9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "alpha-1,2-mannosyltransferase activity", "id": "GO:0000026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000026", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9" } ], "pmid": "" }, { "name": "dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity", "id": "GO:0120564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120564", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GPI anchor biosynthetic process", "id": "GO:0006506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006506", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "61000", "name": "", "equation": "a 2-acyl-6-[alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = a 2-acyl-6-(alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7FTZ9-1" ], "evidence": [ { "id": "61000", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61000" } ] }, { "id": "61004", "name": "", "equation": "a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol + a di-trans,poly-cis-dolichyl phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7FTZ9-1" ], "evidence": [ { "id": "61004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7FTZ9", "gene_name": "Pigb", "activity": [ { "ec_number": "2.4.1.-", "activity": "", "evidence": [ { "id": "A0A9J7FTZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTZ9" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 367, "end_pos": 369 }, { "start_pos": 380, "end_pos": 382 }, { "start_pos": 400, "end_pos": 402 }, { "start_pos": 533, "end_pos": 535 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268209" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Robo2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28", "locus": {} } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05726", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05726", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07693", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07693", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20952", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20952", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750990", "url": "https://www.ncbi.nlm.nih.gov/gene/100750990", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750990", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750990", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FU28", "url": "https://www.orthodb.org/?gene=A0A9J7FU28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231:SF242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231:SF242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268209", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FU28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU28-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU44", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU44-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JG53", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JG53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JG53-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JG53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKQ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMN3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPPMFTLLLLFGFLCILIDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKAMSTDEGTYMCIAENRVGKVEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPSSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGDPLPVISWLKEGFTFLGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKSYDINDLPGPPSKPQVTDVTKNSVTLSWQPGTPGVLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVIVRLHTPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQASTAWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIVGGRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNANDPNYPWLADSWPATSLPVNNSNSGPNEIANFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTTYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKSSSKTQKNNGSTWANVPLPPPPVQPLPGTELGHYAAEQQENGYDSDSWCPPLPVQTYLHQGMEDELEEDDDRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPVPPLGYVSGALISDLETDVPDEDADDEEEALEIARPLRALDQTPGSSMDNLDSSVTGSMVNGWGSASDEDRNFSSHRSSVGSSSDGSIFASGSFAQALVAAADKAGFRLDGTSLTRTGKAFTSSQRPRPTSPFSTDSNTSAALNQSQRPRPTKKHKGGRMDTQPVLPHRREGMPDDLPPPPDPPPSQGLRQQIGLTQHSGNVENSTERKGSSLERQQAANLEDTKSSLDCPAKTALEWQRPTQDWINSTERQEDTRKGQHKQGVGSEESLVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRGGHQRNASDLLDIGYVGSNSQGQFTGEL", "length": 1534, "header": "tr|A0A9J7FU28-1|A0A9J7FU28_CRIGR Isoform 1 of Roundabout homolog 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Robo2 PE=3 SV=1 CANONICAL=A0A9J7FU28-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FU28-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28/entry#A0A9J7FU28-1", "sequence": { "sequence": "MSPPMFTLLLLFGFLCILIDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKAMSTDEGTYMCIAENRVGKVEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPSSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGDPLPVISWLKEGFTFLGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKSYDINDLPGPPSKPQVTDVTKNSVTLSWQPGTPGVLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVIVRLHTPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQASTAWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIVGGRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNANDPNYPWLADSWPATSLPVNNSNSGPNEIANFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTTYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKSSSKTQKNNGSTWANVPLPPPPVQPLPGTELGHYAAEQQENGYDSDSWCPPLPVQTYLHQGMEDELEEDDDRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPVPPLGYVSGALISDLETDVPDEDADDEEEALEIARPLRALDQTPGSSMDNLDSSVTGSMVNGWGSASDEDRNFSSHRSSVGSSSDGSIFASGSFAQALVAAADKAGFRLDGTSLTRTGKAFTSSQRPRPTSPFSTDSNTSAALNQSQRPRPTKKHKGGRMDTQPVLPHRREGMPDDLPPPPDPPPSQGLRQQIGLTQHSGNVENSTERKGSSLERQQAANLEDTKSSLDCPAKTALEWQRPTQDWINSTERQEDTRKGQHKQGVGSEESLVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRGGHQRNASDLLDIGYVGSNSQGQFTGEL", "length": 1534, "header": "tr|A0A9J7FU28-1|A0A9J7FU28_CRIGR Isoform 1 of Roundabout homolog 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Robo2 PE=3 SV=1 CANONICAL=A0A9J7FU28-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FU44-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28/entry#A0A9J7FU44-1", "sequence": { "sequence": "MSPPMFTLLLLFGFLCILIDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKAMSTDEGTYMCIAENRVGKVEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPSSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGDPLPVISWLKEGFTFLGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKSYDINDLPGPPSKPQVTDVTKNSVTLSWQPGTPGVLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVIVRLHTPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQASTAWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIVGGRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNANDPNYPWLADSWPATSLPVNNSNSGPNEIANFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTTYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKSSSKTQKNNGSTWANVPLPPPPVQPLPGTELGHYAAEQQENGYDSDSWCPPLPVQTYLHQGMEDELEEDDDRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPVPPLGYVSGALISDLETDVPDEDADDEEEALEIARPLRALDQTPGSSMDNLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALNQSQRPRPTKKHKGGRMDTQPVLPHRREGMPDDLPPPPDPPPSQGLRQQIGLTQHSGNVENSTERKGSSLERQQAANLEDTKSSLDCPAKTALEWQRPTQDWINSTERQEDTRKGQHKQGVGSEESLVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRGGHQRNASDLLDIGYVGSNSQGQFTGEL", "length": 1473, "header": "tr|A0A9J7FU44-1|A0A9J7FU44_CRIGR Computationally mapped isoform of Roundabout homolog 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Robo2 PE=3 SV=1 CANONICAL=A0A9J7FU28-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JG53-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28/entry#A0A9J7JG53-1", "sequence": { "sequence": "MLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKAMSTDEGTYMCIAENRVGKVEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPSSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGDPLPVISWLKEGFTFLGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKSYDINDLPGPPSKPQVTDVTKNSVTLSWQPGTPGVLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVIVRLHTPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQASTAWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIVGGRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNANDPNYPWLADSWPATSLPVNNSNSGPNEIANFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTTYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKSSSKTQKNNGSTWANVPLPPPPVQPLPGTELGHYAAEQQENGYDSDSWCPPLPVQTYLHQGMEDELEEDDDRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPVPPLGYVSGALISDLETDVPDEDADDEEEALEIARPLRALDQTPGSSMDNLDSSVTGSMVNGWGSASDEDRNFSSHRSSVGSSSDGSIFASGSFAQALVAAADKAGFRLDGTSLTRTGKAFTSSQRPRPTSPFSTDSNTSAALNQSQRPRPTKKHKGGRMDTQPVLPHRREGMPDDLPPPPDPPPSQGLRQQIGLTQHSGNVENSTERKGSSLERQQAANLEDTKSSLDCPAKTALEWQRPTQDWINSTERQEDTRKGQHKQGVGSEESLVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRGGHQRNASDLLDIGYVGSNSQGQFTGEL", "length": 1452, "header": "tr|A0A9J7JG53-1|A0A9J7JG53_CRIGR Computationally mapped isoform of Roundabout homolog 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Robo2 PE=4 SV=1 CANONICAL=A0A9J7FU28-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28/entry#A0A9J7JKQ6-1", "sequence": { "sequence": "MSPPMFTLLLLFGFLCILIDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKAMSTDEGTYMCIAENRVGKVEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPSSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGDPLPVISWLKEGFTFLGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKSYDINDLPGPPSKPQVTDVTKNSVTLSWQPGTPGVLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVIVRLHTPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQASTAWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIVGGRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNANDPNYPWLADSWPATSLPVNNSNSGPNEIANFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTTYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKSSSKTQKNNGSTWANVPLPPPPVQPLPGTELGHYAAEQQENGYDSDSWCPPLPVQTYLHQGMEDELEEDDDRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPVPPLGYVSGALISDLETDVPDEDADDEEEALEIARPLRALDQTPGSSMDNLDSSVTGSMVNGWGSASDEDRNFSSHRSSVGSSSDGSIFASGSFAQALVAAADKAGFRLDGTSLTRTGKAFTSSQRPRPTSPFSTDSNTSAALNQSQRPRPTKKHKGGRMDTQPVLPHRREGMPDDLPPPPDPPPSQGLRQQIGLTQHSGNVENSTERKGSSLERQQAANLEDTKSSLDCPAKTALEWQRPTQDWINSTERQEDTRKGQHKQGVGSEESLVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRGGHQRNASDLLDIGYVGSNSQGQFTE", "length": 1532, "header": "tr|A0A9J7JKQ6-1|A0A9J7JKQ6_CRIGR Computationally mapped isoform of Roundabout homolog 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Robo2 PE=3 SV=1 CANONICAL=A0A9J7FU28-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JMN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28/entry#A0A9J7JMN3-1", "sequence": { "sequence": 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"length": 1382, "header": "tr|A0A9J7JMN3-1|A0A9J7JMN3_CRIGR Computationally mapped isoform of Roundabout homolog 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Robo2 PE=3 SV=1 CANONICAL=A0A9J7FU28-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28/entry#A0A9J7JNH0-1", "sequence": { "sequence": "MSPPMFTLLLLFGFLCILIDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYTLRIKKAMSTDEGTYMCIAENRVGKVEASATLTVRVRPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPSSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPINQTLAVDGTALLKCKATGDPLPVISWLKEGFTFLGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKSYDINDLPGPPSKPQVTDVTKNSVTLSWQPGTPGVLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVIVRLHTPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQASTAWQNLDAKVPTERSAVLVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSHNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHINKTVDAAIRSVVIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIVGGRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIWLYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNANDPNYPWLADSWPATSLPVNNSNSGPNEIANFGRGDVLPPVPGQGDKTATMLSDGAIYSSIDFTTKTTYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKSSSKTQKNNGSTWANVPLPPPPVQPLPGTELGHYAAEQQENGYDSDSWCPPLPVQTYLHQGMEDELEEDDDRVPTPPVRGVASSPAISFGQQSTATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNTPPPQPPVPPLGYVSGALISDLETDVPDEDADDEEEALEIARPLRALDQTPGSSMDNLDSSVTGSMVNGWGSASDEDRNFSSHRSSVGSSSDGSIFASGSFAQALVAAADKAGFRLDGTSLTRTGKAFTSSQRPRPTSPFSTDSNTSAALNQSQRPRPTKKHKGGRMDTQPVLPHRREGMPDEESLVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRGGHQRNASDLLDIGYVGSNSQGQFTGEL", "length": 1443, "header": "tr|A0A9J7JNH0-1|A0A9J7JNH0_CRIGR Computationally mapped isoform of Roundabout homolog 2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Robo2 PE=3 SV=1 CANONICAL=A0A9J7FU28-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 550, "start_aa": "Thr", "end_pos": 550, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr550", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750990", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750990", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "chemotaxis", "id": "GO:0006935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006935", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28" } ], "pmid": "" }, { "name": "axon midline choice point recognition", "id": "GO:0016199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016199", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28" } ], "pmid": "" }, { "name": "regulation of multicellular organismal process", "id": "GO:0051239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051239", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28" } ], "pmid": "" }, { "name": "regulation of anatomical structure morphogenesis", "id": "GO:0022603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022603", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU28" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": 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"olfactory receptor 13A1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265016" }, "gene_names": [ { "name": "LOC100761217", "type": "recommended", "evidence": [ { "id": "A0A9J7FU32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32" } ] }, { "name": "LOC100761217", "type": "synonym", "evidence": [ { "id": "XP_027265016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265016" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7FU32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 13A1-like", "type": "synonym", "evidence": [ { "id": "XP_027265016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265016" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265016" } ] }, { "annotation": "Possible taste receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32#function" }, { "database": "UniProtKB", "id": "ARBA00053672", "url": "https://www.uniprot.org/uniprotkb/ARBA00053672#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100761217", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32", "locus": {} } ], "crossref": [ { "id": "A0A9J7FU32", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FU32", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15232", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15232", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761217", "url": "https://www.ncbi.nlm.nih.gov/gene/100761217", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761217", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761217", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FU32", "url": "https://www.orthodb.org/?gene=A0A9J7FU32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265016", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FU32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU32-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPILSIMMLTPNQTRVTEFVLEGFSEHPTLRFLLIGCFLTLYTMALIGNTVIIALVTSSNGLHSPMYFFLCNLATMDIVCTSSVLPKALLGLVSEENTISFKGCMAQLFFLVWSLSSELLLLTVMAYDRYVAICHPLHYSSRMSPHLCGALALGVWSICALNASINTGLMTRLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLMADAFYGGINFFLTLLSYGCIIASVLRMRSAEGKKKAFSTCSSHLIVVCVYYSSVFCAYISPASSYSPERSKVTSVLYSVLSPTLNPLIYTLRNKDVKLALGRLLSSFSH", "length": 318, "header": "tr|A0A9J7FU32-1|A0A9J7FU32_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100761217 PE=3 SV=1 CANONICAL=A0A9J7FU32-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FU32-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32/entry#A0A9J7FU32-1", "sequence": { "sequence": "MDPILSIMMLTPNQTRVTEFVLEGFSEHPTLRFLLIGCFLTLYTMALIGNTVIIALVTSSNGLHSPMYFFLCNLATMDIVCTSSVLPKALLGLVSEENTISFKGCMAQLFFLVWSLSSELLLLTVMAYDRYVAICHPLHYSSRMSPHLCGALALGVWSICALNASINTGLMTRLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLMADAFYGGINFFLTLLSYGCIIASVLRMRSAEGKKKAFSTCSSHLIVVCVYYSSVFCAYISPASSYSPERSKVTSVLYSVLSPTLNPLIYTLRNKDVKLALGRLLSSFSH", "length": 318, "header": "tr|A0A9J7FU32-1|A0A9J7FU32_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100761217 PE=3 SV=1 CANONICAL=A0A9J7FU32-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761217", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761217", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU32", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FU32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU32" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 298, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 }, { "start_pos": 163, "end_pos": 165 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FU38-1", "uniprot_ac": "A0A9J7FU38", "uniprot_id": "A0A9J7FU38_CRIGR", "mass": { "chemical_mass": 76248.0, "monoisotopic_mass": 76248.0 }, "refseq": { "ac": "XP_027268445", "name": "protein Aster-C isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268445" }, "gene_names": [ { "name": "Gramd1c", "type": "recommended", "evidence": [ { "id": "A0A9J7FU38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU38" } ] }, { "name": "Gramd1c", "type": "synonym", "evidence": [ { "id": "XP_027268445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268445" } ] } ], "protein_names": [ { "name": "Protein Aster-C isoform X4", "type": "synonym", "evidence": [ { "id": "A0A9J7FU38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU38/entry#names_and_taxonomy" } ] }, { "name": "protein Aster-C isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027268445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268445" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268445" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU38", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU38" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gramd1c", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU38", "locus": {} } ], "crossref": [ { "id": "A0A9J7FU38", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FU38", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13220", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13220", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773582", "url": "https://www.ncbi.nlm.nih.gov/gene/100773582", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773582", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773582", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FU38", "url": "https://www.orthodb.org/?gene=A0A9J7FU38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23319", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23319", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23319:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23319:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FU38", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU38-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMU0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGALRARQAVNEGDSSVATELQEEAEENPSPVVDENNIVSAKKQGPSTHNWSGDWSFWISSSTYKDRNEEYKQQFTHLPDSEKLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEENVQPRSPERNSVDDSGERDEKFSKAISFTQESISRVSETESLDGNSPKRGLGKEESQSEKHLKKSLSLVSEKRLSRTPSKSLDLNKNEYLSLDKSSTSDSVDEENIPEKDLQGRLHINRVFHISAERMFELLFTSSHFMQRFTNSRNIIDVVSTPWSVESGGDQLRTMTYTIVLSNPLTGKCTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCIVRSAKQRCRLRVSTDLKYRKQPWGIIKSLIEKNSWSSLENYFKQLESDLLMEESVLNQSIEDPGKLSSLRRRRRTLNRTAETAPKPSSQRSPIDVGFEAKGDITGKRKTVDSCDAVLIMVMSVFLLLLVVLNVTLFLKLSKIEHAAQSFYQLHLQEEKSFSLASDRFSSTENIQKNKDQAHHLKGVLQDSIVMLEQLKNSLIMLQKTFDLLSKNRTGVAVES", "length": 664, "header": "tr|A0A9J7FU38-1|A0A9J7FU38_CRIGR Isoform 1 of Protein Aster-C isoform X4 OS=Cricetulus griseus OX=10029 GN=Gramd1c PE=4 SV=1 CANONICAL=A0A9J7FU38-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FU38-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU38/entry#A0A9J7FU38-1", "sequence": { "sequence": "MEGALRARQAVNEGDSSVATELQEEAEENPSPVVDENNIVSAKKQGPSTHNWSGDWSFWISSSTYKDRNEEYKQQFTHLPDSEKLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEENVQPRSPERNSVDDSGERDEKFSKAISFTQESISRVSETESLDGNSPKRGLGKEESQSEKHLKKSLSLVSEKRLSRTPSKSLDLNKNEYLSLDKSSTSDSVDEENIPEKDLQGRLHINRVFHISAERMFELLFTSSHFMQRFTNSRNIIDVVSTPWSVESGGDQLRTMTYTIVLSNPLTGKCTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCIVRSAKQRCRLRVSTDLKYRKQPWGIIKSLIEKNSWSSLENYFKQLESDLLMEESVLNQSIEDPGKLSSLRRRRRTLNRTAETAPKPSSQRSPIDVGFEAKGDITGKRKTVDSCDAVLIMVMSVFLLLLVVLNVTLFLKLSKIEHAAQSFYQLHLQEEKSFSLASDRFSSTENIQKNKDQAHHLKGVLQDSIVMLEQLKNSLIMLQKTFDLLSKNRTGVAVES", "length": 664, "header": "tr|A0A9J7FU38-1|A0A9J7FU38_CRIGR Isoform 1 of Protein Aster-C isoform X4 OS=Cricetulus griseus OX=10029 GN=Gramd1c PE=4 SV=1 CANONICAL=A0A9J7FU38-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JMU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU38/entry#A0A9J7JMU0-1", "sequence": { "sequence": "MEGALRARQAVNEGDSSVATELQEEAEENPSPVVDENNIVSAKKQGPSTHNWSGDWSFWISSSTYKDRNEEYKQQFTHLPDSEKLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEENVQPRSPERNSVDDSGERDEKFSKAISFTQESISRVSETESLDGNSPKRGLGKEESQSEKHLKKSLSLVSEKRLSRTPSKSLDLNKNEYLSLDKSSTSDSVDEENIPEKDLQGRLHINRVFHISAERMFELLFTSSHFMQRFTNSRNIIDVVSTPWSVESGGDQLRTMTYTIVLSNPLTGKCTAATEKQTLYKESREAQFYLVDSEVLTHDVPYHDYFYTLNRYCIVRSAKQRCRLRVSTDLKYRKQPWGIIKSLIEKNSWSSLENYFKQLESDLLMEESVLNQSIEDPGKLSSLRRRRRTLNRTAETAPKPSSQRSPIDVGFEAKGDITGKRKTVDSCDAVLIMVMSVFLLLLVVLNVTLFLKLSKIEHAAQSFYQLHLQEEKSFS", "length": 603, "header": "tr|A0A9J7JMU0-1|A0A9J7JMU0_CRIGR Computationally mapped isoform of Protein Aster-C isoform X5 OS=Cricetulus griseus OX=10029 GN=Gramd1c PE=4 SV=1 CANONICAL=A0A9J7FU38-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU38/entry#A0A9J7JNP0-1", "sequence": { "sequence": 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##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614171.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505669" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU51", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU51" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100770448", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU51", "locus": {} } ], "crossref": [ { "id": "A0A9J7FU51", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FU51", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15947", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15947", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770448", "url": "https://www.ncbi.nlm.nih.gov/gene/100770448", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770448", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770448", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FU51", "url": "https://www.orthodb.org/?gene=A0A9J7FU51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003505669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505669", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FU51", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU51-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWANESIIEEFVLLGFSDQPWLEFPLFVVFLTSYIVTIFGNFNIILVSRLDPKLHTPMYFFLTNLSVIDLCYITCTVPQLLVNLRSMRKVISYGGCVVQLYMFLSLGATECILLPVMSLDRFVAICRPLHYSVIMHQRFCLQLAAVSWIIGFGNSVWPSILTLQLPRCGHYVIDHFLCELPVMIKLSCVDTTVNETELFFGSVFFHLVPLTLILISYAFIAQAIFKIQSAEGRQKAFGTCGSHLIVVSVFYGTAISMYLLPPSPQSQNRRKTASLFYGIISPMLNPLIYTLRNKEVKEAFKRLVKRVFLTKKYLIWDP", "length": 319, "header": "tr|A0A9J7FU51-1|A0A9J7FU51_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100770448 PE=3 SV=1 CANONICAL=A0A9J7FU51-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FU51-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU51/entry#A0A9J7FU51-1", "sequence": { "sequence": "MSWANESIIEEFVLLGFSDQPWLEFPLFVVFLTSYIVTIFGNFNIILVSRLDPKLHTPMYFFLTNLSVIDLCYITCTVPQLLVNLRSMRKVISYGGCVVQLYMFLSLGATECILLPVMSLDRFVAICRPLHYSVIMHQRFCLQLAAVSWIIGFGNSVWPSILTLQLPRCGHYVIDHFLCELPVMIKLSCVDTTVNETELFFGSVFFHLVPLTLILISYAFIAQAIFKIQSAEGRQKAFGTCGSHLIVVSVFYGTAISMYLLPPSPQSQNRRKTASLFYGIISPMLNPLIYTLRNKEVKEAFKRLVKRVFLTKKYLIWDP", "length": 319, "header": "tr|A0A9J7FU51-1|A0A9J7FU51_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100770448 PE=3 SV=1 CANONICAL=A0A9J7FU51-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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{ "id": "100759272", "url": "https://www.ncbi.nlm.nih.gov/gene/100759272", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039398", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039398", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759272", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759272", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FU95", "url": "https://www.orthodb.org/?gene=A0A9J7FU95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12622", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12622", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23222", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23222", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268562", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FU95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU95-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVV3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSNCPSSPLLVRLPKSIPWAHRKLEKYFQSRASGGGECTVQPVGPNAPDTFEVKFLERAAKEGVLKKREHKMLIDDKPVTIFLETIKKPVEDLRPRSPSLTQSPDETPSSRPLSLTQSPDETPSSRPLSLTQSTSETPSSRPPSLTQSTSETPSSRPPSLTQSLDEPLSDKESASNSVDSVVQKVFLAVTAELNCELLSKEQRARIATVYPGVRSVEGKDGIAKVCGNFKDIEKIHHFLSGQLLESEQKQKYPPQNYPTSDVEREPPKDSGRGFSSSEPKARLQDAFEVPVLFLEYFRHACPGRIESIEKKFGVNIQVGDSTPNMVSVVFTTSQSGNIEAARESFVRDFQECTQSLKQDCVSIEDPQIAKELRRELNRCFPKLLIKGQERTLTLLGSQADISAATEKVSQTSIKTPVKIMASGYKAGIDVDSTHFNLLKPELLQEISEIESKYNTSGKVQEKSQKTCIQFDPKDKEIDLSVHSYASFTDAFQHATCQLRTEVLSLKHLGKGKAHLHKTKFVDDLKKKHPNVHFVISRESMTLIGLPNQLAQAKHYVFKRMGLSPSSGEKLNVDDETPMDIDENDSNAAVPPLRGSADSSGALKANETEDYCVICMDTIRNKRVLSKCKHEFCTSCITKAMSLKPVCPVCQTSYGIQRGNQPDGGTMTSDTLRQSLPGYEDCGTIVIRYDIKSGIQTNEHPNPGKPYPGTHRSAYLPDNKEGREVLDLLREAFRKKLIFTIGNSRVTGASDVITWNDIHHKTSTFGGPENFGYPDPDYLKRVKEELKAKGIE", "length": 793, "header": "tr|A0A9J7FU95-1|A0A9J7FU95_CRIGR Isoform 1 of E3 ubiquitin-protein ligase OS=Cricetulus griseus OX=10029 GN=Dtx3l PE=3 SV=1 CANONICAL=A0A9J7FU95-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FU95-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95/entry#A0A9J7FU95-1", "sequence": { "sequence": "MASSNCPSSPLLVRLPKSIPWAHRKLEKYFQSRASGGGECTVQPVGPNAPDTFEVKFLERAAKEGVLKKREHKMLIDDKPVTIFLETIKKPVEDLRPRSPSLTQSPDETPSSRPLSLTQSPDETPSSRPLSLTQSTSETPSSRPPSLTQSTSETPSSRPPSLTQSLDEPLSDKESASNSVDSVVQKVFLAVTAELNCELLSKEQRARIATVYPGVRSVEGKDGIAKVCGNFKDIEKIHHFLSGQLLESEQKQKYPPQNYPTSDVEREPPKDSGRGFSSSEPKARLQDAFEVPVLFLEYFRHACPGRIESIEKKFGVNIQVGDSTPNMVSVVFTTSQSGNIEAARESFVRDFQECTQSLKQDCVSIEDPQIAKELRRELNRCFPKLLIKGQERTLTLLGSQADISAATEKVSQTSIKTPVKIMASGYKAGIDVDSTHFNLLKPELLQEISEIESKYNTSGKVQEKSQKTCIQFDPKDKEIDLSVHSYASFTDAFQHATCQLRTEVLSLKHLGKGKAHLHKTKFVDDLKKKHPNVHFVISRESMTLIGLPNQLAQAKHYVFKRMGLSPSSGEKLNVDDETPMDIDENDSNAAVPPLRGSADSSGALKANETEDYCVICMDTIRNKRVLSKCKHEFCTSCITKAMSLKPVCPVCQTSYGIQRGNQPDGGTMTSDTLRQSLPGYEDCGTIVIRYDIKSGIQTNEHPNPGKPYPGTHRSAYLPDNKEGREVLDLLREAFRKKLIFTIGNSRVTGASDVITWNDIHHKTSTFGGPENFGYPDPDYLKRVKEELKAKGIE", "length": 793, "header": "tr|A0A9J7FU95-1|A0A9J7FU95_CRIGR Isoform 1 of E3 ubiquitin-protein ligase OS=Cricetulus griseus OX=10029 GN=Dtx3l PE=3 SV=1 CANONICAL=A0A9J7FU95-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95/entry#A0A9J7FVV3-1", "sequence": { "sequence": "MASSNCPSSPLLVRLPKSIPWAHRKLEKYFQSRASGGGECTVQPVGPNAPDTFEVKFLERAAKEGVLKKREHKMLIDDKPVTIFLETIKKPVEDLRPRSPSLTQSPDETPSSRPLSLTQSTSETPSSRPPSLTQSTSETPSSRPPSLTQSLDEPLSDKESASNSVDSVVQKVFLAVTAELNCELLSKEQRARIATVYPGVRSVEGKDGIAKVCGNFKDIEKIHHFLSGQLLESEQKQKYPPQNYPTSDVEREPPKDSGRGFSSSEPKARLQDAFEVPVLFLEYFRHACPGRIESIEKKFGVNIQVGDSTPNMVSVVFTTSQSGNIEAARESFVRDFQECTQSLKQDCVSIEDPQIAKELRRELNRCFPKLLIKGQERTLTLLGSQADISAATEKVSQTSIKTPVKIMASGYKAGIDVDSTHFNLLKPELLQEISEIESKYNTSGKVQEKSQKTCIQFDPKDKEIDLSVHSYASFTDAFQHATCQLRTEVLSLKHLGKGKAHLHKTKFVDDLKKKHPNVHFVISRESMTLIGLPNQLAQAKHYVFKRMGLSPSSGEKLNVDDETPMDIDENDSNAAVPPLRGSADSSGALKANETEDYCVICMDTIRNKRVLSKCKHEFCTSCITKAMSLKPVCPVCQTSYGIQRGNQPDGGTMTSDTLRQSLPGYEDCGTIVIRYDIKSGIQTNEHPNPGKPYPGTHRSAYLPDNKEGREVLDLLREAFRKKLIFTIGNSRVTGASDVITWNDIHHKTSTFGGPENFGYPDPDYLKRVKEELKAKGIE", "length": 778, "header": "tr|A0A9J7FVV3-1|A0A9J7FVV3_CRIGR Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Cricetulus griseus OX=10029 GN=Dtx3l PE=3 SV=1 CANONICAL=A0A9J7FU95-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759272", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759272", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FU95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU95" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 613, "end_pos": 652, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 456, "end_pos": 458 }, { "start_pos": 585, "end_pos": 587 }, { "start_pos": 607, "end_pos": 609 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FUA0-1", "uniprot_ac": "A0A9J7FUA0", "uniprot_id": "A0A9J7FUA0_CRIGR", "mass": { "chemical_mass": 34884.0, "monoisotopic_mass": 34884.0 }, "refseq": { "ac": "XP_027268059", "name": "olfactory receptor 145-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268059" }, "gene_names": [ { "name": "LOC100754776", "type": "recommended", "evidence": [ { "id": "A0A9J7FUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0" } ] }, { "name": "LOC100754776", "type": "synonym", "evidence": [ { "id": "XP_027268059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268059" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7FUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 145-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027268059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268059" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268059" } ] }, { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100754776", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0", "locus": {} } ], "crossref": [ { "id": "A0A9J7FUA0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FUA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100754776", "url": "https://www.ncbi.nlm.nih.gov/gene/100754776", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754776", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754776", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FUA0", "url": "https://www.orthodb.org/?gene=A0A9J7FUA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268059", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FUA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVANDSMVTEFILLGLTGQPNLQIPLFLLFLVMYMITALGNLVLIILIVLNSHLHTPMYFFLSNLSFVDFCYSSVITPKMLMNFILKENIISYVGCMTQFYLFCFCVISECYVLTSMAYDRYVAICNPLLYNVAMSHKVCSYLMLGSYFMGFSSAMIHTGYVLRLTFCDGKTIDHYFCDALPLLQLSCTNTYVNKIEIFIVAGKDIIVPTFIIFISYGFVLSSIFQMRSTEGRSKAFSTCSSHIIAVSLFFGSGAFMYLKPNSAGPRNNGKASSIIYTTVIPMLNPLVYSLRNKDVKAALRNTLSKKIF", "length": 310, "header": "tr|A0A9J7FUA0-1|A0A9J7FUA0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100754776 PE=3 SV=1 CANONICAL=A0A9J7FUA0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FUA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0/entry#A0A9J7FUA0-1", "sequence": { "sequence": "MTVANDSMVTEFILLGLTGQPNLQIPLFLLFLVMYMITALGNLVLIILIVLNSHLHTPMYFFLSNLSFVDFCYSSVITPKMLMNFILKENIISYVGCMTQFYLFCFCVISECYVLTSMAYDRYVAICNPLLYNVAMSHKVCSYLMLGSYFMGFSSAMIHTGYVLRLTFCDGKTIDHYFCDALPLLQLSCTNTYVNKIEIFIVAGKDIIVPTFIIFISYGFVLSSIFQMRSTEGRSKAFSTCSSHIIAVSLFFGSGAFMYLKPNSAGPRNNGKASSIIYTTVIPMLNPLVYSLRNKDVKAALRNTLSKKIF", "length": 310, "header": "tr|A0A9J7FUA0-1|A0A9J7FUA0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100754776 PE=3 SV=1 CANONICAL=A0A9J7FUA0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"UniProtKB", "id": "A0A9J7FUA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FUA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUA0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027268388.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268388", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268388" } ] }, { "annotation": "Serine protease which preferentially hydrolyzes peptides with Arg at the P1 position.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3#function" }, { "database": "UniProtKB", "id": "ARBA00057398", "url": "https://www.uniprot.org/uniprotkb/ARBA00057398#function" }, { "database": "UniProtKB", "id": "A0A9J7GYR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYR3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmprss7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3", "locus": {} } ], "crossref": [ { "id": "A0A9J7FUC3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FUC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764328", "url": "https://www.ncbi.nlm.nih.gov/gene/100764328", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000082", "database": "InterPro", "categories": [ "Protein 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CANONICAL=A0A9J7FUC3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FUC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3/entry#A0A9J7FUC3-1", "sequence": { "sequence": 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CANONICAL=A0A9J7FUC3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3/entry#A0A9J7GYR3-1", "sequence": { "sequence": "MFCITNIEFLPEYRQKESREFLSMAKTVQQVVNLVYTTSAFSKFYKQSVVTDVSNNKGGLLVHFWIVFVMPHAKGHIFCEECVAAILKDSIQTSIINRTSVGNLQGLAVDMDSVVLNDKGCSKYFYADHPTLRYPLEISATSGQLMCHFKLVAIVGYLIRLSIESIQLEADNCITDSLTVYDSLLPIRSATLYRICEPTRTLMSFVSTNNLMLVTLKSPYVRRLSGIRAYFEVIPEQKCENTILVKDINSFEGKISSPYYPSYYPPKCKCTWKFQTPLTTLGIALKFYNYSITKKSIKGCEHGWWEINEHMYCGSYMDHETIFRVPSPLVHIQLQCSSRLSDKPLLVEYGSYNISQPCPAGSFRCSSGLCIPEAQRCDGVNDCFDESDELFCVTAKPACNASIFRQRGPLVCDGFWDCEDGQDEQNCTRSIPCTKRTFKCGNDICFQKQNAQCDGVVDCPDGSDEEGCGCSRSSSSLHRIVGGYDSQEGTWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPAGQKVRGGEKCWVTGWGRRHETDKKGSSVLQQAEVELIDQTICVSTYGIITSRMLCAGVMSGKSDACKGDSGGPLSCRRKSDGRWILTGIVSWGHGCGRPNFPGVYTRVSNFVPWIHKYVPSLL", "length": 717, "header": "tr|A0A9J7GYR3-1|A0A9J7GYR3_CRIGR Computationally mapped isoform of Transmembrane protease serine 7 OS=Cricetulus griseus OX=10029 GN=Tmprss7 PE=4 SV=1 CANONICAL=A0A9J7FUC3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764328", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764328", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FUC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 223, "end_pos": 346, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FUC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 592, "end_pos": 826, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FUC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC3" }, { "id": "PS50024", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50024" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEA", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 220, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 465, "end_pos": 467 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 538, "end_pos": 540 } ] }, "class_list": [], "section_stats": [ { 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FUE2-1", "uniprot_ac": "A0A9J7FUE2", "uniprot_id": "A0A9J7FUE2_CRIGR", "mass": { "chemical_mass": 33850.0, "monoisotopic_mass": 33850.0 }, "refseq": { "ac": "XP_003497897", "name": "OX-2 membrane glycoprotein-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497897" }, "gene_names": [ { "name": "LOC100764624", "type": "recommended", "evidence": [ { "id": "A0A9J7FUE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUE2" } ] }, { "name": "LOC100764624", "type": "synonym", "evidence": [ { "id": "XP_003497897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497897" } ] } ], "protein_names": [ { "name": "OX-2 membrane glycoprotein-like", "type": "synonym", "evidence": [ { "id": "XP_003497897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497897" }, { "id": "A0A9J7FUE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUE2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613667.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003497897.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497897" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUE2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764624", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUE2", "locus": {} } ], "crossref": [ { "id": "A0A9J7FUE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FUE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05846", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05846", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764624", "url": "https://www.ncbi.nlm.nih.gov/gene/100764624", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764624", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764624", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWQKIQN", "url": "https://omabrowser.org/oma/group/TWQKIQN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FUE2", "url": "https://www.orthodb.org/?gene=A0A9J7FUE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46841", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46841", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46841:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46841:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497897", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FUE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHICTQESESSQKIKHNNYETAVLGRNVTIFCNLTSLANVLQVTWQKIQGSLHENIGTYSHKYGENILPPYVNRLQCNILEPNASFITIQELTFEDEACYKCLFNTFPDGSYGEQTCLNILTVSQLITELHSVPGSEDLLNLHCSAVGKPAPGISIYPSQDLVYSQEELFTKNPNTTVTITKIYNISLKTVRSLGLHDVVVCMTHPLRYEEKIVPLPINQEGTKNHPLEWQNTAVVFIILFFISCIIIATVLYFKVKKKRSENTPEPSSAQMPNPLSTLVPTPSSTETENLVNQHHQTKT", "length": 301, "header": "tr|A0A9J7FUE2-1|A0A9J7FUE2_CRIGR Isoform 1 of OX-2 membrane glycoprotein-like OS=Cricetulus griseus OX=10029 GN=LOC100764624 PE=4 SV=1 CANONICAL=A0A9J7FUE2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FUE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUE2/entry#A0A9J7FUE2-1", "sequence": { "sequence": "MLHICTQESESSQKIKHNNYETAVLGRNVTIFCNLTSLANVLQVTWQKIQGSLHENIGTYSHKYGENILPPYVNRLQCNILEPNASFITIQELTFEDEACYKCLFNTFPDGSYGEQTCLNILTVSQLITELHSVPGSEDLLNLHCSAVGKPAPGISIYPSQDLVYSQEELFTKNPNTTVTITKIYNISLKTVRSLGLHDVVVCMTHPLRYEEKIVPLPINQEGTKNHPLEWQNTAVVFIILFFISCIIIATVLYFKVKKKRSENTPEPSSAQMPNPLSTLVPTPSSTETENLVNQHHQTKT", "length": 301, "header": "tr|A0A9J7FUE2-1|A0A9J7FUE2_CRIGR Isoform 1 of OX-2 membrane glycoprotein-like OS=Cricetulus griseus OX=10029 GN=LOC100764624 PE=4 SV=1 CANONICAL=A0A9J7FUE2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": 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REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265280", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265280" } ] }, { "annotation": "Protease that may play a role in T-cell development.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUF0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUF0#function" }, { "database": "UniProtKB", "id": "ARBA00058062", "url": "https://www.uniprot.org/uniprotkb/ARBA00058062#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUF0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUF0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prss16", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUF0", "locus": {} } ], "crossref": [ { "id": "A0A9J7FUF0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FUF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100770760", "url": "https://www.ncbi.nlm.nih.gov/gene/100770760", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770760", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770760", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FUF0", "url": "https://www.orthodb.org/?gene=A0A9J7FUF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11010", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11010", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11010:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11010:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265280", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265280", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FUF0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVKAPWLGFLLLVSLWGLSDPALLLRRLREHIQKFQESSSMNPGFGLSQGLVAVPKQGWLEQPLDPFNTSDRRTFLQRYWVNDRHRAGQDAPVFLHIGGEGSLGPGSVMAGHPVALAPAWGALVISLEHRFYGLSMPSGGLDMAQLRYLSSRHALADVASARQALSRLLNVSSSSPWICFGGSYAGSLATWTRLKFPHLVFAAVASSAPLSAVLDFYAYNEVVARSLSQVAIGGSQECLAAASAAFAEVERLLRAGPAAQAVLREELSACGSLDLTEDQGELLGALQALVGGTVQYDGQAGAPLSVRQLCGLLLGDSGNRTHSTPYLGLRRAVQIVLRTMGQRCLSFSRAETVAQLRSTEPQVSGVGDRQWLYQTCTEFGYYVTCEGPQCPFSQLPALPSHLDLCEQVFGLSAASVAQAVAQTNSYYGGQTPGATQVLYVNGDTDPWHVLSVTQDLGPSEPAILIPSASHCFDMAPMRPSDSPSLRLGRQRIFQQLQVWLKDLKKNLD", "length": 509, "header": "tr|A0A9J7FUF0-1|A0A9J7FUF0_CRIGR Isoform 1 of Thymus-specific serine protease OS=Cricetulus griseus OX=10029 GN=Prss16 PE=3 SV=1 CANONICAL=A0A9J7FUF0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FUF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUF0/entry#A0A9J7FUF0-1", "sequence": { "sequence": "MAVKAPWLGFLLLVSLWGLSDPALLLRRLREHIQKFQESSSMNPGFGLSQGLVAVPKQGWLEQPLDPFNTSDRRTFLQRYWVNDRHRAGQDAPVFLHIGGEGSLGPGSVMAGHPVALAPAWGALVISLEHRFYGLSMPSGGLDMAQLRYLSSRHALADVASARQALSRLLNVSSSSPWICFGGSYAGSLATWTRLKFPHLVFAAVASSAPLSAVLDFYAYNEVVARSLSQVAIGGSQECLAAASAAFAEVERLLRAGPAAQAVLREELSACGSLDLTEDQGELLGALQALVGGTVQYDGQAGAPLSVRQLCGLLLGDSGNRTHSTPYLGLRRAVQIVLRTMGQRCLSFSRAETVAQLRSTEPQVSGVGDRQWLYQTCTEFGYYVTCEGPQCPFSQLPALPSHLDLCEQVFGLSAASVAQAVAQTNSYYGGQTPGATQVLYVNGDTDPWHVLSVTQDLGPSEPAILIPSASHCFDMAPMRPSDSPSLRLGRQRIFQQLQVWLKDLKKNLD", "length": 509, "header": "tr|A0A9J7FUF0-1|A0A9J7FUF0_CRIGR Isoform 1 of Thymus-specific serine protease OS=Cricetulus griseus OX=10029 GN=Prss16 PE=3 SV=1 CANONICAL=A0A9J7FUF0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003614599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016834395", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834395" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arl6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4", "locus": {} } ], "crossref": [ { "id": "A0A9J7FUJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FUJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04157", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04157", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773053", "url": "https://www.ncbi.nlm.nih.gov/gene/100773053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773053", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773053", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NKPWHIC", "url": "https://omabrowser.org/oma/group/NKPWHIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MTK0", "url": "https://www.orthodb.org/?gene=A0A8C2MTK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FUJ4", "url": "https://www.orthodb.org/?gene=A0A9J7FUJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016834395", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834395", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MTK0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MTK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLLDKLSGLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQCQDIVPTIGFTIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDAVTSVKVSQLLCLESIKDKPWHICASDAIKGEGLQEGVDWLQGTSHTTVHL", "length": 187, "header": "tr|A0A9J7FUJ4-1|A0A9J7FUJ4_CRIGR Isoform 1 of ADP-ribosylation factor-like protein 6 OS=Cricetulus griseus OX=10029 GN=Arl6 PE=3 SV=1 CANONICAL=A0A9J7FUJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MTK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4/entry#A0A8C2MTK0-1", "sequence": 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"glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773053", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773053", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1ULC5-1", "protein_name": "ADP-ribosylation factor-like protein 6", "gene_name": "ARL6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLLDRLSGLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSSDRLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDAVTSVKVSQLLCLENIKDKPWHICASDAIKGEGLQEGVDWLQDQIQAVKT", "length": 186 }, "evidence": [ { "id": "A0A9J7FUJ4", "url": "https://omabrowser.org/oma/group/A0A9J7FUJ4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XWU7-1", "protein_name": "ADP ribosylation factor like GTPase 6", "gene_name": "CRYBG3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGLFDKLAGWLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQTQDIVPTIGFSIEKFKTSSLSFTVFDMSGQGRYRNLWEHYYNSENKGSEAINLKSNQKESTTLPALLKVYPNEEKNHSTEELSKSDIQEELKKANSLPSLTPGNKAADKDKQPREGFFQFLGSLFNLATKSSLVDSKPPACQDEPNRCEKDLQSTNTLTEGTQPQHPKTEEPVCSTAGIKEDSLNKDDMIMNNVGKDSSQDQQGGQKRSADVKKQIQRKPQAPAVTYATYRGSARIRQLLKSQSEMTEKGEENTENKNASVIKENGEIQTVVSPKSEHLTKENGEDENKDHEDDVIVNSSTVKMELKKSGETQHYLGSNKHEIMPNASASSTGSSSGVDLEHTPALEANKVKRTYSQDSLLSSSRNSEIPTSSTHQITSALSAVDSLFGKELGEAEAPFQMDKKATSNCEKETHCSDQSYQESTEKMQDGCLQSLRSNDTVNKEPQLSKGEYCCSHQMNNHSELTSNVQMHHSNTTFQQQADEHKGSANKDSDPRKSDAQKIVAAAEKEQNPQNFLATVLSPFKKQTCTSLSVESRGEECIATGNLTASKLAVKNDNDTVVDQVTCNEELNELGKPMHIQNEHQLNLVENSKDTATPQPGLSCLEKMKVLSEVAVESFADVSRTRECDNVKSNLDELTATLSVSFESSFETGDCYSASLHPDCKSVSKTIVKRGVGSKDKRDAVSTPDLEYEKSKSFETVDMSLSENSIPTHGTVSHKTVQDIPKKTLVTLAEDNTSKSSPFPLDSTERTDDPTPAASKISEAGMNEMALTPFESKNCISELSPHISKSQEKNLEVSYSALRCEGKPLTDHFSTICEKDIDVDIISASPPSCESRHINISSKVESNNKHGISSTVLYSSSDNQGKVPSLATNSENGQVARWSAASKQDSCVFLTADSNRIIPEDRMTETPRCSEDLRASCPPISLEPEFTPAELHHFTSEVDVQDFCSARPPSPTQESKEGSNLSISALETSGTAQENCSSSGHRVGVEAEELSSAQQAGDSVLAEAMPSPVCPWKRASNSECTEVCKNAVQQVNLCNETAGMSEALSEKGEQTAAAATESNDLYFEKIWKSTNGVGQDCTDLQDTSLLFKKAEEIVDSVLHLAIEEIIAKQAVGVCQVCGRKDSLVNKDILNDQKTLQLEAEEIQSAVHSLKHFNESSRGGSFSFTGNEMCGTNNQDETIPSYIPAKTDLHSVLALKAREIIDEVINSAKQKLTSNQWQGRESEKHSEKIERKPMAENPEILNLDGNLSSETQELIREPAGKAETQNISINCEKAVCSGPPLLPNSMDNSIDWLQRDEDVPNNAIACQTNGFLSTGSSVRPESTPMILAKEECDKKVCEHLAAAETCGKAGLSATSRKSDVSLHLINRDAAVTEEISLPLQLNDSCSNTDTPELMLLPSVNVNLSSFMPDEESISTLSEYKVKRSPRGSAESSAEGNLDEHSGREAAETLSQVIAALEDSKVGESKEEVAKRTSETALVNIELNTQFIDSELPVTEEHSEGKNYFNSVYAQNKENLKEVEMKDSDLQRYNHLEENGLDCTNDMKESADLLGFSPLIEQRENSSFTIVYEGALQTENKSVSTGDDSSSDLPLDSVGFLMCERPKNKNDPTCFYGKNNNLNKATEGNSSESFLCVEAKRYRVYPLSLSPIYEDDSSHEDLLSADMSPEGHPNGVSKDNFDHTSVLSLLQSVSERLQLTTQFSKEENEEGMEDEDEEESSYEGKVLDVERGEEECLSSHWTRNLTAAALSNDQNIYPLPEQSPFLSKEQLGSKEQTGQFQDETSLGQTYCNTVLQKADTTLKYPPTSAYYQYLRSANNYSSEKGTRFGNILQDILQPKIRWSQDHVMPKLGELPVNLVDRASLTYNPRPGKIIIYDIHGDKSKQEIHSDVLDATSWIFPIGALLRIIRGCWIFYEKPKFHGQKYVLEEGETVLDHLWDLPGVKHHRRSLTVGSIKHVTKDCSVPEIEFSVGANTEGLPICIQSAVANLEELDVEKNPYIHVKSGIWLAYSDLNYKGEMKILEECSELSEIPSADVRSVRPLKMGGLKVQMPMNVKIIIYEKTHFGGWSKEFSENISSVLALFGNEEDFQEIGSIRVIGGVWVAYDKERYKGRQYLLEEGDYEDMHTWGGTGSVLLSFRFLQADFIESSVALFQSDDEDGKALDIVNEEIPDLEQTGFGPETKSILVKSGVWVAYQQKHFCGEQYVLEKGKYKCFFDWGGSSKIIMSIRPIKLEPLGTNEPPHLLKAFSNTHFQGACIDFTAEVSDFTSFIPCSFKVLRGCWLLYYQGETDDDHCVLEEGLYIDLPSCGCPTAAIKSLKPIEYVFAEPSLSLFALESCKGRELHFSEPVNSVLNEDLHFYAQSVWVRSGLWIAYEGCNFLGKQILLEPGEISNWNEYSGWKVIGSLRPVKQPAVYLRIRNRAQGKYLTVAGSLADVRATSVCVSPYSGRDTQIWHYCRGLFKSKVNDACLDVIGGRDVPGAKVALWAEHGKERQKWRLNEDGTISSYLSDQLVLDIKGGNYYDKNHIVMNEPEEDKRSQKWDIEIL", "length": 2586 }, "evidence": [ { "id": "A0A9J7FUJ4", "url": "https://omabrowser.org/oma/group/A0A9J7FUJ4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A1ZBK9-1", "protein_name": "ADP-ribosylation factor-like protein 6", "gene_name": "Arl6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGMLHNLADLIKIKKDKMTILVLGLNNSGKSSIINHFKKSSEQTSIVVPTVGFMVEQFYIGMSGVSIKAIDMSGATRYRNLWEHQFKNCHGIIYVIDSSDRMRFVVVKDELDLVLQHPDLCNRIVPILFYGNKMDMEDSLSSVKIAAALRLENIKDKPWHICSSSAISGEGLGEGVQWLIQQMRFAMLNNKNAAKSRSKHSK", "length": 202 }, "evidence": [ { "id": "A0A9J7FUJ4", "url": "https://omabrowser.org/oma/group/A0A9J7FUJ4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O88848-1", "protein_name": "ADP-ribosylation factor-like protein 6", "gene_name": "Arl6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLDRLSGLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKDGQAIIFVIDSSDKLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDSVTSVKVSQLLCLESIKDKPWHICASDAIKGEGLQEGVDWLQDQIQAVKT", "length": 186 }, "evidence": [ { "id": "A0A9J7FUJ4", "url": "https://omabrowser.org/oma/group/A0A9J7FUJ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0IIM2-1", "protein_name": "ADP-ribosylation factor-like protein 6", "gene_name": "ARL6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGLLDRLSGLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQDIVPTIGFSIQKFKSSSLSFTVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSSDKLRMVVAKEELRTLLNHPDIKHRRIPILFFANKMDLRDALTSVKVSQLLCLEDIKDKPWHICASDAIKGEGLQEGVDWLQDQIQSVKT", "length": 186 }, "evidence": [ { "id": "A0A9J7FUJ4", "url": "https://omabrowser.org/oma/group/A0A9J7FUJ4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5M9P8-1", "protein_name": "ADP-ribosylation factor-like protein 6", "gene_name": "arl6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGLFDKLAGWLGLKKKEVNVLCLGLDNSGKTTIINQLKPSNAQAQDIVPTIGFSIEKFKTSSLSFTVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSGDKLRMVVAKEELDTLLNHPDIKHRRIPLLFFANKMDLRDALSAVKVSQLLCLENIKDKPWHICASDAVKGEGLLEGVDWLQDQIRAMKT", "length": 186 }, "evidence": [ { "id": "A0A9J7FUJ4", "url": "https://omabrowser.org/oma/group/A0A9J7FUJ4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9H0F7-1", "protein_name": "ADP-ribosylation factor-like protein 6", "gene_name": "ARL6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLDRLSVLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQNILPTIGFSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSSDRLRMVVAKEELDTLLNHPDIKHRRIPILFFANKMDLRDAVTSVKVSQLLCLENIKDKPWHICASDAIKGEGLQEGVDWLQDQIQTVKT", "length": 186 }, "evidence": [ { "id": "A0A9J7FUJ4", "url": "https://omabrowser.org/oma/group/A0A9J7FUJ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "pmid": "" }, { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "pmid": "" }, { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A8C2MTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTK0#function" }, { "id": "A0A8C2MTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTK0" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" }, { "id": "A0A9J7FUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4#function" }, { "id": "A0A9J7FUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "binding_site_uniprot": 31, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 31, "end_pos": 31, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTK0#function" }, { "id": "A0A8C2MTK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTK0" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" }, { "id": "A0A9J7FUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4#function" }, { "id": "A0A9J7FUJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ4" } ], "binding_site_uniprot": 50, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 50, "end_pos": 50, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FUJ5-1", "uniprot_ac": "A0A9J7FUJ5", "uniprot_id": "A0A9J7FUJ5_CRIGR", "mass": { "chemical_mass": 25429.0, "monoisotopic_mass": 25429.0 }, "refseq": { "ac": "XP_003495674", "name": "LOW QUALITY PROTEIN: bcl-2-related protein A1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495674" }, "gene_names": [ { "name": "Bcl2a1", "type": "recommended", "evidence": [ { "id": "A0A9J7FUJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ5" } ] }, { "name": "Bcl2a1", "type": "synonym", "evidence": [ { "id": "XP_003495674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495674" } ] } ], "protein_names": [ { "name": "Bcl-2-related protein A1", "type": "recommended", "evidence": [ { "id": "A0A9J7FUJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ5/entry#names_and_taxonomy" } ] }, { "name": "Hemopoietic-specific early response protein", "type": "synonym", "evidence": [ { "id": "A0A9J7FUJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ5/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: bcl-2-related protein A1", "type": "synonym", "evidence": [ { "id": "XP_003495674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495674" } ] }, { "name": "Protein BFL-1", "type": "synonym", "evidence": [ { "id": "A0A9J7FUJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUJ5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003495674.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495674" } ] }, { "annotation": "Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268307" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUM0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7FYN5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUM0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": 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Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758669", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758669", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FUM0", "url": "https://www.orthodb.org/?gene=A0A9J7FUM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF41", "url": 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"length": 1078, "header": "tr|A0A9J7FUM0-1|A0A9J7FUM0_CRIGR Isoform 1 of Zinc finger and BTB domain-containing protein 11 OS=Cricetulus griseus OX=10029 GN=Zbtb11 PE=4 SV=1 CANONICAL=A0A9J7FUM0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUM0/entry#A0A9J7FYN5-1", "sequence": { "sequence": 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"length": 1052, "header": "tr|A0A9J7FYN5-1|A0A9J7FYN5_CRIGR Computationally mapped isoform of Zinc finger and BTB domain-containing protein 11 OS=Cricetulus griseus OX=10029 GN=Zbtb11 PE=4 SV=1 CANONICAL=A0A9J7FUM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUM0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUM0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758669", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758669", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUM0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUM0", "url": 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Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613618.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007646933.1. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUY6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUY6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766765", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUY6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUY6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUY6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUY6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUY6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUY6", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FYV1-1", "uniprot_ac": "A0A9J7FYV1", "uniprot_id": "A0A9J7FYV1_CRIGR", "mass": { "chemical_mass": 111700.0, "monoisotopic_mass": 111700.0 }, "refseq": { "ac": "XP_027271761", "name": "squamous cell carcinoma antigen recognized by T-cells 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271761" }, "gene_names": [ { "name": "LOC100762447", "type": "recommended", "evidence": [ { "id": "A0A9J7FYV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ] }, { "name": "LOC100762447", "type": "synonym", "evidence": [ { "id": "XP_027271761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271761" } ] } ], "protein_names": [ { "name": "Spliceosome associated factor 3, U4/U6 recycling protein", "type": "recommended", "evidence": [ { "id": "A0A9J7FYV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1/entry#names_and_taxonomy" } ] }, { "name": "Squamous cell carcinoma antigen recognized by T-cells 3", "type": "synonym", "evidence": [ { "id": "A0A9J7FYV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1/entry#names_and_taxonomy" } ] }, { "name": "squamous cell carcinoma antigen recognized by T-cells 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027271761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271761" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271761", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271761" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100762447", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12391", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12391", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12392", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12392", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762447", "url": "https://www.ncbi.nlm.nih.gov/gene/100762447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034218", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034218", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762447", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762447", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FYV1", "url": "https://www.orthodb.org/?gene=A0A9J7FYV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15481", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15481", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15481:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15481:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17204", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17204", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17204:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17204:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271761", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271761", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MNR3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MNR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ16", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ16-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAAAASASEPEVEPQAGPEAEGGEDEAKAASADRNVQSRAVASDAAKTKGPGWDLQREGVSESDGDEEDAMASSAESSPGEDEWEYDEEEEKNQLEIERLEEQLSINGYDYNCHVELIRLLRLEGELNKVRMARQKMSELFPLTEELWLEWLHDEISMAMDGLDREHVYELFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARPIAAFLSPSDREQTFDSQLEKVHSLFRRQLAIPLYDMEATLAEYEEWSEDPIPESVLQSYQKALEQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSRYLDRQLKVKDLVLSVHSRAVRNCPWTVGLWSRYLLAMERHGVDHQMISATFENALSAGFIQATDYVEIWQVYLDYLRRRVDFRQDSSKELEELRSMFTRALEYLQQEVEERFSESGDPSCVIMQSWARVEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDVAIQKTETRLARVNEQRMKAAEKEAALVQQEEERAEQRKKVRAEKKALKKKKKTHGADKRKADEEDEREWGEEEEEQPSKRRRVENSLASGVASAMQEETELSGKCVTIDVASPSKQKEKAASLKLDMPKVAHDSSKDSVTVFVSNLPYSMDEPEAKLRPLFEACGEVVQIRPVFSNRGDFRGYCYVEFKEEKSAQQALELDRKNVEGRPMFVSPCVDKSKNPDFKVFRYSTTLEKHKLFISGLPFSCTKEELEDICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIKENVIKVAISNPPQRKVPEKPEVRTAPGAPMVPRQMYGARGKGRTQLALLPRALQRHSAAPQAENGPAVGPAVTTSMATEAPKMSNADFAKLLLRK", "length": 980, "header": "tr|A0A9J7FYV1-1|A0A9J7FYV1_CRIGR Isoform 1 of Spliceosome associated factor 3, U4/U6 recycling protein OS=Cricetulus griseus OX=10029 GN=LOC100762447 PE=4 SV=1 CANONICAL=A0A9J7FYV1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MNR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1/entry#A0A8C2MNR3-1", "sequence": { "sequence": "MATAAAASASEPEVEPQAGPEAEGGEDEAKAASADRNVQSRAVASDAAKTKGPGWDLQREGVSESDGDEEDAMASSAESSPGEDEWEYDEEEEKNQLEIERLEEQLSINGYDYNCHVELIRLLRLEGELNKVRMARQKMSELFPLTEELWLEWLHDEISMAMDGLDREHVYELFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARLEKVHSLFRRQLAIPLYDMEATLAEYEEWSEDPIPESVLQSYQKALEQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSRYLDRQLKVKDLVLSVHSRAVRNCPWTVGLWSRYLLAMERHGVDHQMISATFENALSAGFIQATDYVEIWQVYLDYLRRRVDFRQDSSKELEELRSMFTRALEYLQQEVEERFSESGDPSCVIMQSWARVEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDVAIQKTETRLARVNEQRMKAAEKEAALVQQEEERAEQRKKVRAEKKALKKKKKTHGADKRKADEEDEREWGEEEEEQPSKRRRVENSLASGVASAMQEETELSGKCVTIDVASPSKQKEKAASLKLDMPKVAHDSSKDSVTVFVSNLPYSMDEPEAKLRPLFEACGEVVQIRPVFSNRGDFRGYCYVEFKEEKSAQQALELDRKNVEGRPMFVSPCVDKSKNPDFKVFRYSTTLEKHKLFISGLPFSCTKEELEDICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIKENVIKVAISNPPQRKVPEKPEVRTAPGAPMVPRQMYGARGKGRTQLALLPRALQRHSAAPQAENGPAVGPAVTTSMATEAPKMSNADFAKLLLRK", "length": 962, "header": "tr|A0A8C2MNR3-1|A0A9J7FYV1_CRIGR Computationally mapped isoform of Spliceosome associated factor 3, U4/U6 recycling protein OS=Cricetulus griseus OX=10029 GN=LOC100762447 PE=4 SV=1 CANONICAL=A0A9J7FYV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1/entry#A0A9J7FYV1-1", "sequence": { "sequence": "MATAAAASASEPEVEPQAGPEAEGGEDEAKAASADRNVQSRAVASDAAKTKGPGWDLQREGVSESDGDEEDAMASSAESSPGEDEWEYDEEEEKNQLEIERLEEQLSINGYDYNCHVELIRLLRLEGELNKVRMARQKMSELFPLTEELWLEWLHDEISMAMDGLDREHVYELFERAVKDYICPNIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLAIWEAYREFESAIVEAARPIAAFLSPSDREQTFDSQLEKVHSLFRRQLAIPLYDMEATLAEYEEWSEDPIPESVLQSYQKALEQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSRYLDRQLKVKDLVLSVHSRAVRNCPWTVGLWSRYLLAMERHGVDHQMISATFENALSAGFIQATDYVEIWQVYLDYLRRRVDFRQDSSKELEELRSMFTRALEYLQQEVEERFSESGDPSCVIMQSWARVEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDVAIQKTETRLARVNEQRMKAAEKEAALVQQEEERAEQRKKVRAEKKALKKKKKTHGADKRKADEEDEREWGEEEEEQPSKRRRVENSLASGVASAMQEETELSGKCVTIDVASPSKQKEKAASLKLDMPKVAHDSSKDSVTVFVSNLPYSMDEPEAKLRPLFEACGEVVQIRPVFSNRGDFRGYCYVEFKEEKSAQQALELDRKNVEGRPMFVSPCVDKSKNPDFKVFRYSTTLEKHKLFISGLPFSCTKEELEDICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIKENVIKVAISNPPQRKVPEKPEVRTAPGAPMVPRQMYGARGKGRTQLALLPRALQRHSAAPQAENGPAVGPAVTTSMATEAPKMSNADFAKLLLRK", "length": 980, "header": "tr|A0A9J7FYV1-1|A0A9J7FYV1_CRIGR Isoform 1 of Spliceosome associated factor 3, U4/U6 recycling protein OS=Cricetulus griseus OX=10029 GN=LOC100762447 PE=4 SV=1 CANONICAL=A0A9J7FYV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZ16-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1/entry#A0A9J7FZ16-1", "sequence": { "sequence": "MDPLQSDRQLKVKDLVLSVHSRAVRNCPWTVGLWSRYLLAMERHGVDHQMISATFENALSAGFIQATDYVEIWQVYLDYLRRRVDFRQDSSKELEELRSMFTRALEYLQQEVEERFSESGDPSCVIMQSWARVEARLCNNMQKARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHVCEVLLTMERTEGTLEDWDVAIQKTETRLARVNEQRMKAAEKEAALVQQEEERAEQRKKVRAEKKALKKKKKTHGADKRKADEEDEREWGEEEEEQPSKRRRVENSLASGVASAMQEETELSGKCVTIDVASPSKQKEKAASLKLDMPKVAHDSSKDSVTVFVSNLPYSMDEPEAKLRPLFEACGEVVQIRPVFSNRGDFRGYCYVEFKEEKSAQQALELDRKNVEGRPMFVSPCVDKSKNPDFKVFRYSTTLEKHKLFISGLPFSCTKEELEDICKAHGTVKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIKENVIKVAISNPPQRKVPEKPEVRTAPGAPMVPRQMYGARGKGRTQLALLPRALQRHSAAPQAENGPAVGPAVTTSMATEAPKMSNADFAKLLLRK", "length": 613, "header": "tr|A0A9J7FZ16-1|A0A9J7FZ16_CRIGR Computationally mapped isoform of Squamous cell carcinoma antigen recognized by T-cells 3 isoform X5 OS=Cricetulus griseus OX=10029 GN=LOC100762447 PE=4 SV=1 CANONICAL=A0A9J7FYV1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MNR3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNR3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MNR3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNR3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762447", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762447", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "regulation of RNA metabolic process", "id": "GO:0051252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051252", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ], "pmid": "" }, { "name": "spliceosomal tri-snRNP complex assembly", "id": "GO:0000244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000244", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ], "pmid": "" }, { "name": "transcription elongation-coupled chromatin remodeling", "id": "GO:0140673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140673", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ], "pmid": "" }, { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "U6atac snRNA binding", "id": "GO:0030624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030624", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ], "pmid": "" }, { "name": "U4 snRNA binding", "id": "GO:0030621", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030621", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV1" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": 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This record is derived from a genomic sequence (NW_003614144.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016832589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832589" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYH6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYH6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zdhhc3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYH6", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYH6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYH6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100760307", "url": "https://www.ncbi.nlm.nih.gov/gene/100760307", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760307", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760307", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VCVVMTW", "url": "https://omabrowser.org/oma/group/VCVVMTW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MNS2", "url": "https://www.orthodb.org/?gene=A0A8C2MNS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FYH6", "url": "https://www.orthodb.org/?gene=A0A9J7FYH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016832589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832589", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MNS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYH6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY11-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY11-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLTPTRHSRDIERKPEYLQPEKCAPPPFPGPAGTMWFIRDGCGIACAIVTWFLVLYAEFVVLFVMLIPSRDYVYSVINGIVFNLLAFLALASHCRAMLTDPGAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLILLCFEALLFLIFTSVMFGTQVHSICTDETGIERLQRKKQPRERTGSCKSVQEAFGGDFSLNWFNPFTRPCQPEIPIDKGLVRQASSLSDMDNMETTESQLETKDRDSVEVLDE", "length": 331, "header": "tr|A0A9J7FYH6-1|A0A9J7FYH6_CRIGR Isoform 1 of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc3 PE=3 SV=1 CANONICAL=A0A9J7FYH6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MNS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYH6/entry#A0A8C2MNS2-1", "sequence": { "sequence": 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"header": "tr|A0A9J7FYH6-1|A0A9J7FYH6_CRIGR Isoform 1 of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc3 PE=3 SV=1 CANONICAL=A0A9J7FYH6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GY11-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYH6/entry#A0A9J7GY11-1", "sequence": { "sequence": "MDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLHCFEEDWTKCSSFSPPTTVILLILLCFEALLFLIFTSVMFGTQVHSICTDETGIERLQRKKQPRERTGSCKSVQEAFGGDFSLNWFNPFTRPCQPEIPIDKGLVRQASSLSDMDNMETTESQLETKDRDSVEVLDE", "length": 179, "header": "tr|A0A9J7GY11-1|A0A9J7GY11_CRIGR Computationally mapped isoform of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc3 PE=3 SV=1 CANONICAL=A0A9J7FYH6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNS2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MNS2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNS2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760307", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760307", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PVV6-1", "protein_name": "Palmitoyltransferase", "gene_name": "ZDHHC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMISSVHRFRDIERTPEYLQPEKCVPPPSHASLGTMWFIRDGCGIACAVVTWMLVFYADFVVLLVMLVPSRDYVYSVINGTLFNTLAFLALASHFRAMLTDPGAVPKGNATKEFIESLQLKPGQVVYKCPKCCSIKPDRAHHCSVCKRCIRKMDHHCPWVNNCVGENNQKYFVLFTMYIALISLHALIMVGFHFLYCFEEDWTKCSSFSPPTTVILLILLCFEALLFLIFTSVMFGTQVHSICTDETGIEQLKKEERRWAKKTKWMNMKAVFGHPFSIAWLSPFATPDQGKADPYQYVV", "length": 299 }, "evidence": 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"MLSSRAQAARTAADKALQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEVTPRHVTCHTRGALLPGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGALTGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKASENLESALELQDTQSAQKPGLSQPGAPKTQIFMNGACSTSLLPTLSSPMAFSLPVAPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRAEE", "length": 522, "header": "tr|A0A9J7G3D9-1|A0A9J7G3D9_CRIGR Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Cricetulus griseus OX=10029 GN=Usp30 PE=3 SV=1 CANONICAL=A0A9J7G3D9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9/entry#A0A8C2MYU8-1", "sequence": { "sequence": "MLSSRAQAARTAADKALQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEVTPRHVTCHTRGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGALTGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKASENLESALELQDTQSAQKPGLSQPGAPKTQIFMNGACSTSLLPTLSSPMAFSLPVAPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRAEE", "length": 517, "header": "tr|A0A8C2MYU8-1|A0A9J7G3D9_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Cricetulus griseus OX=10029 GN=Usp30 PE=3 SV=1 CANONICAL=A0A9J7G3D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9/entry#A0A9J7FYW1-1", "sequence": { "sequence": "MLSSRAQAARTAADKALQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQSEVTPRHVTCHTRGALLPGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGALTGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKASENLESALELQDTQSAQKPGLSQPGAPKTQIFMNGACSTSLLPTLSSPMAFSLPVAPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRAEE", "length": 521, "header": "tr|A0A9J7FYW1-1|A0A9J7FYW1_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Cricetulus griseus OX=10029 GN=Usp30 PE=3 SV=1 CANONICAL=A0A9J7G3D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9/entry#A0A9J7G3D9-1", "sequence": { "sequence": "MLSSRAQAARTAADKALQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEVTPRHVTCHTRGALLPGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGALTGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKASENLESALELQDTQSAQKPGLSQPGAPKTQIFMNGACSTSLLPTLSSPMAFSLPVAPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRAEE", "length": 522, "header": "tr|A0A9J7G3D9-1|A0A9J7G3D9_CRIGR Isoform 1 of Ubiquitin carboxyl-terminal hydrolase OS=Cricetulus griseus OX=10029 GN=Usp30 PE=3 SV=1 CANONICAL=A0A9J7G3D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JI91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9/entry#A0A9J7JI91-1", "sequence": { "sequence": "MLSSRAQAARTAADKALQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQSEVTPRHVTCHTRGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGALTGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKASENLESALELQDTQSAQKPGLSQPGAPKTQIFMNGACSTSLLPTLSSPMAFSLPVAPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRAEE", "length": 516, "header": "tr|A0A9J7JI91-1|A0A9J7JI91_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Cricetulus griseus OX=10029 GN=Usp30 PE=3 SV=1 CANONICAL=A0A9J7G3D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JN53-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9/entry#A0A9J7JN53-1", "sequence": { "sequence": "MISCDAGECWLLPDDCCVVTSDPSQYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEVTPRHVTCHTRGALLPGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGALTGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKASENLESALELQDTQSAQKPGLSQPGAPKTQIFMNGACSTSLLPTLSSPMAFSLPVAPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRAEE", "length": 519, "header": "tr|A0A9J7JN53-1|A0A9J7JN53_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Cricetulus griseus OX=10029 GN=Usp30 PE=3 SV=1 CANONICAL=A0A9J7G3D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JR35-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9/entry#A0A9J7JR35-1", "sequence": { "sequence": "MKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLNLLKALSCQEVTEDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEVTPRHVTCHTRGALLPGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGALTGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKASENLESALELQDTQSAQKPGLSQPGAPKTQIFMNGACSTSLLPTLSSPMAFSLPVAPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRAEE", "length": 491, "header": "tr|A0A9J7JR35-1|A0A9J7JR35_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase OS=Cricetulus griseus OX=10029 GN=Usp30 PE=3 SV=1 CANONICAL=A0A9J7G3D9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYU8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYU8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MYU8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYU8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772643", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772643", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" }, { "name": "mitochondrial fusion", "id": "GO:0008053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008053", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" }, { "name": "autophagy of mitochondrion", "id": "GO:0000422", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000422", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" }, { "name": "protein K6-linked deubiquitination", "id": "GO:0044313", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044313", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" }, { "name": "protein K11-linked deubiquitination", "id": "GO:0035871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035871", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cysteine-type endopeptidase activity", "id": "GO:0004197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004197", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G3D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D9" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 507, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 291, "end_pos": 293 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FXY0-1", "uniprot_ac": "A0A9J7FXY0", "uniprot_id": "A0A9J7FXY0_CRIGR", "mass": { "chemical_mass": 58045.0, "monoisotopic_mass": 58045.0 }, "refseq": { "ac": "XP_027269317", "name": "protein tweety homolog 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269317" }, "gene_names": [ { "name": "Ttyh3", "type": "recommended", "evidence": [ { "id": "A0A9J7FXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0" } ] }, { "name": "Ttyh3", "type": "synonym", "evidence": [ { "id": "XP_027269317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269317" } ] } ], "protein_names": [ { "name": "Protein tweety homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7FXY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0/entry#names_and_taxonomy" } ] }, { "name": "protein tweety homolog 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027269317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269317" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269317" } ] }, { "annotation": "Probable chloride channel.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QPD2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPD2#function" }, { "database": "UniProtKB", "id": "RU361114", "url": "https://www.uniprot.org/uniprotkb/RU361114#function" }, { "database": "UniProtKB", "id": "A0A9J7FVM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVM2#function" }, { "database": "UniProtKB", "id": "A0A9J7FXY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0#function" }, { "database": "UniProtKB", "id": "A0A9J7H0M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0M5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ttyh3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0", "locus": {} } ], "crossref": [ { "id": "cd07912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07912", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762098", "url": "https://www.ncbi.nlm.nih.gov/gene/100762098", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762098", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762098", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FXY0", "url": "https://www.orthodb.org/?gene=A0A9J7FXY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12424:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12424:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269317", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "66336", "url": "https://www.rhea-db.org/rhea/66336", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QPD2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QPD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0M5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGVSYAAPWWVSLLHRLPHFDLRWEATSSQFRPEDADYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKTDEHLEADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGVHRATYSLRHANRTVAGVQDRVWDTAAALNRTAEPNLQSLERQLVGRQEPLRAVQRLQSLLGTLLGYTAAIPFWRNPGVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDTFVTKMVEEYSVLSGDILQYYLACSPRATNPFQQKLSGSHKALVEMQDVVAELLRTVPREHPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFITALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSEASIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSRYLAALDSGSHAGWQFKPMDSARTLW", "length": 526, "header": "tr|A0A9J7FXY0-1|A0A9J7FXY0_CRIGR Isoform 1 of Protein tweety homolog OS=Cricetulus griseus OX=10029 GN=Ttyh3 PE=3 SV=1 CANONICAL=A0A9J7FXY0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QPD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0/entry#A0A8C2QPD2-1", "sequence": { "sequence": "MAGVSYAAPWWVSLLHRLPHFDLRWEATSSQFRPEDADYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKTDEHLEADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGVHRATYSLRHANRTVAGVQDRVWDTAAALNRTAEPNLQSLERQLVGRQEPLRAVQRLQSLLGTLLGYTAAIPFWRNPGVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDTFVTKMVEEYSVLSGDILQYYLACSPRATNPFQQKLSGSHKALVEMQDVVAELLRTVPREHPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFITALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSEASIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSYTSSMRAKYLATSQPRPDSSGSGH", "length": 524, "header": "tr|A0A8C2QPD2-1|A0A9J7FXY0_CRIGR Computationally mapped isoform of Protein tweety homolog OS=Cricetulus griseus OX=10029 GN=Ttyh3 PE=3 SV=1 CANONICAL=A0A9J7FXY0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0/entry#A0A9J7FVM2-1", "sequence": { "sequence": "MAGVSYAAPWWVSLLHRLPHFDLRWEATSSQFRPEDADYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKTDEHLEADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGVHRATYSLRHANRTVAGVQDRVWDTAAALNRTAEPNLQSLERQLVGRQEPLRAVQRLQSLLGTLLGYTAAIPFWRNPGVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDTFVTKMVEEYSVLSGDILQYYLACSPRATNPFQQKLSGSHKALVEMQDVVAELLRTVPREHPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFITALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSEASIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSVALHAVPHTLGARFPQAAPNLS", "length": 522, "header": "tr|A0A9J7FVM2-1|A0A9J7FVM2_CRIGR Computationally mapped isoform of Protein tweety homolog OS=Cricetulus griseus OX=10029 GN=Ttyh3 PE=3 SV=1 CANONICAL=A0A9J7FXY0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0/entry#A0A9J7FXY0-1", "sequence": { "sequence": "MAGVSYAAPWWVSLLHRLPHFDLRWEATSSQFRPEDADYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKTDEHLEADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGVHRATYSLRHANRTVAGVQDRVWDTAAALNRTAEPNLQSLERQLVGRQEPLRAVQRLQSLLGTLLGYTAAIPFWRNPGVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDTFVTKMVEEYSVLSGDILQYYLACSPRATNPFQQKLSGSHKALVEMQDVVAELLRTVPREHPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFITALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSEASIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSRYLAALDSGSHAGWQFKPMDSARTLW", "length": 526, "header": "tr|A0A9J7FXY0-1|A0A9J7FXY0_CRIGR Isoform 1 of Protein tweety homolog OS=Cricetulus griseus OX=10029 GN=Ttyh3 PE=3 SV=1 CANONICAL=A0A9J7FXY0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H0M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0/entry#A0A9J7H0M5-1", "sequence": { "sequence": "MAGVSYAAPWWVSLLHRLPHFDLRWEATSSQFRPEDADYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKTDEHLEADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGVHRATYSLRHANRTVAGVQDRVWDTAAALNRTAEPNLQSLERQLVGRQEPLRAVQRLQSLLGTLLGYTAAIPFWRNPGVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDTFVTKMVEEYSVLSGDILQYYLACSPRATNPFQQKLSGSHKALVEMQDVVAELLRTVPREHPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFITALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSEASIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSLLP", "length": 503, "header": "tr|A0A9J7H0M5-1|A0A9J7H0M5_CRIGR Computationally mapped isoform of Protein tweety homolog OS=Cricetulus griseus OX=10029 GN=Ttyh3 PE=3 SV=1 CANONICAL=A0A9J7FXY0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QPD2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPD2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QPD2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPD2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762098", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762098", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "volume-sensitive chloride channel activity", "id": "GO:0072320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072320", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0" } ], "pmid": "" }, { "name": "intracellularly calcium-gated chloride channel activity", "id": "GO:0005229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005229", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-glutamate transmembrane transport", "id": "GO:0015813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "66336", "name": "", "equation": "L-glutamate(out) = L-glutamate(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "66336", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/66336" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 144, "end_pos": 146 }, { "start_pos": 351, "end_pos": 353 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FYT8-1", "uniprot_ac": "A0A9J7FYT8", "uniprot_id": "A0A9J7FYT8_CRIGR", "mass": { "chemical_mass": 134103.0, "monoisotopic_mass": 134103.0 }, "refseq": { "ac": "XP_016831190", "name": "PR domain zinc finger protein 15 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831190" }, "gene_names": [ { "name": "Prdm15", "type": "recommended", "evidence": [ { "id": "A0A9J7FYT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" } ] }, { "name": "Prdm15", "type": "synonym", "evidence": [ { "id": "XP_016831190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831190" } ] } ], "protein_names": [ { "name": "PR domain zinc finger protein 15", "type": "recommended", "evidence": [ { "id": "A0A9J7FYT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8/entry#names_and_taxonomy" } ] }, { "name": "PR domain zinc finger protein 15 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016831190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831190" } ] }, { "name": "PR domain-containing protein 15", "type": "synonym", "evidence": [ { "id": "A0A9J7FYT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613905.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016831190.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016831190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831190" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prdm15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYT8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19199", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19199", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763200", "url": "https://www.ncbi.nlm.nih.gov/gene/100763200", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763200", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763200", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERGPWAC", "url": "https://omabrowser.org/oma/group/ERGPWAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FYT8", "url": "https://www.orthodb.org/?gene=A0A9J7FYT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HFC9", "url": "https://www.orthodb.org/?gene=G3HFC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF193", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF193", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21549", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21549", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23573", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23573", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016831190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831190", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FYK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G323", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G323", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G323-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G323-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HFC9", "url": "https://www.uniprot.org/uniprotkb/G3HFC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HFC9-1", "url": "https://www.uniprot.org/uniprotkb/G3HFC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRHRPPGFRCCAVSGADRNPESGSDPALHIPQVPTMAEDGNEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSRDIPAGTELRVWYAAFYAKKMDKPMLKQACSSIQAAGTPEPSVPTEPERGQWVCKVCSSAFLELQLLNEHLLGHLEQAKSLPAGGQQHEAASEKEPDTPRRESPTTAESKSIQSVVATKEPKKKPRRGRKPKASKVEQPLVIIKEKEPAEHVAEIITEVPPDEPVSATPDERIMELVLGKLATPTNEVSSVPKFTHHQSSTIALKRGLVLSSRHGVRRKLVRQLGEHKRIHQCGTCSKVFQNSSNLSRHVRSHGECAHGDKLFKCEECSKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKATKRSHKRKQKPEEEAGAPVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSSVGLTNITVTPITTTAGTQFTNLQPVAVGHLTNPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAVPQTDVLQPPQAPAAPQQAVQPQVQNEQQQMYSY", "length": 1184, "header": "tr|A0A9J7FYT8-1|A0A9J7FYT8_CRIGR Isoform 1 of PR domain zinc finger protein 15 OS=Cricetulus griseus OX=10029 GN=Prdm15 PE=4 SV=1 CANONICAL=A0A9J7FYT8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8/entry#A0A9J7FYK3-1", "sequence": { "sequence": "MPRHRPPGFRCCAVSGADRNPESGSDPALHIPQVPTMAEDGNEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSRDIPAGTELRVWYAAFYAKKMDKPMLKQACSSIQAAGTPEPSVPTEPERGQWVCKVCSSAFLELQLLNEHLLGHLEQAKSLPAGGQQHEAASEKEPDTPRRESPTTAESKSIQSVVATKEPKKKPRRGRKPKASKVEQPLVIIKEKEPAEHVAEIITEVPPDEPVSATPDERIMELVLGKLATPTNEVSSVPKFTHHQSSTIALKRGLVLSSRHGVRRKLVRQLGDKLFKCEECSKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKATKRSHKRKQKPEEEAGAPVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSSVGLTNITVTPITTTAGTQFTNLQPVAVGHLTNPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAVPQTDVLQPPQAPAAPQQAVQPQVQNEQQQMYSY", "length": 1150, "header": "tr|A0A9J7FYK3-1|A0A9J7FYK3_CRIGR Computationally mapped isoform of PR domain zinc finger protein 15 OS=Cricetulus griseus OX=10029 GN=Prdm15 PE=4 SV=1 CANONICAL=A0A9J7FYT8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8/entry#A0A9J7FYT8-1", "sequence": { "sequence": "MPRHRPPGFRCCAVSGADRNPESGSDPALHIPQVPTMAEDGNEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSRDIPAGTELRVWYAAFYAKKMDKPMLKQACSSIQAAGTPEPSVPTEPERGQWVCKVCSSAFLELQLLNEHLLGHLEQAKSLPAGGQQHEAASEKEPDTPRRESPTTAESKSIQSVVATKEPKKKPRRGRKPKASKVEQPLVIIKEKEPAEHVAEIITEVPPDEPVSATPDERIMELVLGKLATPTNEVSSVPKFTHHQSSTIALKRGLVLSSRHGVRRKLVRQLGEHKRIHQCGTCSKVFQNSSNLSRHVRSHGECAHGDKLFKCEECSKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKATKRSHKRKQKPEEEAGAPVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSSVGLTNITVTPITTTAGTQFTNLQPVAVGHLTNPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAVPQTDVLQPPQAPAAPQQAVQPQVQNEQQQMYSY", "length": 1184, "header": "tr|A0A9J7FYT8-1|A0A9J7FYT8_CRIGR Isoform 1 of PR domain zinc finger protein 15 OS=Cricetulus griseus OX=10029 GN=Prdm15 PE=4 SV=1 CANONICAL=A0A9J7FYT8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G323-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8/entry#A0A9J7G323-1", "sequence": { "sequence": "MPRHRPPGFRCCAVSGADRNPESGSDPALHIPQVPTMAEDGNEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSRDIPAGTELRVWYAAFYAKKMDKPMLKQACSSIQAAGTPEPSVPTEPERGQWVCKVCSSAFLELQLLNEHLLGHLEQAKSLPAGGQQHEAASEKEPDTPRRESPTTAESKSIQSVVATKEPKKKPRRGRKPKASKVEQPLVIIKEKEPAEHVAEIITEVPPDEPVSATPDERIMELVLGKLATPTNEVSSVPKFTHHQSSTIALKRGLVLSSRHGVRRKLVRQLGEHKRIHQCGTCSKVFQNSSNLSRHVRSHGDKLFKCEECSKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKATKRSHKRKQKPEEEAGAPVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSSVGLTNITVTPITTTAGTQFTNLQPVAVGHLTNPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAVPQTDVLQPPQAPAAPQQAVQPQVQNEQQQMYSY", "length": 1179, "header": "tr|A0A9J7G323-1|A0A9J7G323_CRIGR Computationally mapped isoform of PR domain zinc finger protein 15 OS=Cricetulus griseus OX=10029 GN=Prdm15 PE=4 SV=1 CANONICAL=A0A9J7FYT8-1" }, "locus": {} }, { "isoform_ac": "G3HFC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8/entry#G3HFC9-1", "sequence": { "sequence": "MAEDGNEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSRDIPAGTELRVWYAAFYAKKMDKPMLKQACSSIQAAGTPEPSVPTEPERGQWVCKVCSSAFLELQLLNEHLLGHLEQAKSLPAGGQQHEAASEKEPDTPRRESPTTAESKSIQSVVATKEPKKKPRRGRKPKASKVEQPLVIIKEKEPAEHVAEIITEVPPDEPVSATPDERIMELVLGKLATPTNEVSSVPKFTHHQSSTIALKRGLVLSSRHGVRRKLVRQLGEHKRIHQCGTCSKVFQNSSNLSRHVRSHGECAHGDKLFKCEECSKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKATKRSHKRKQKPEEEAGAPVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSSVGLTNITVTPITTTAGTQFTNLQPVAVGHLTNPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAVPQTDVLQPPQAPAAPQQAVQPQVQNEQQQMYSY", "length": 1148, "header": "tr|G3HFC9-1|A0A9J7FYT8_CRIGR Computationally mapped isoform of PR domain zinc finger protein 15 OS=Cricetulus griseus OX=10029 GN=Prdm15 PE=4 SV=1 CANONICAL=A0A9J7FYT8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 349, "start_aa": "Thr", "end_pos": 349, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr349", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HFC9", "url": "https://www.uniprot.org/uniprotkb/G3HFC9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HFC9", "url": "https://www.uniprot.org/uniprotkb/G3HFC9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763200", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763200", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y7A8-1", "protein_name": "PR domain zinc finger protein 15", "gene_name": "PRDM15", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEDGSDETMFVWCEDCGQYHDSECPELGPVVTVKDSFVLSRARSSLPSNLEIRQLEDGTEGVFALTQLVKRTQFGPFESKRVAKLEKETVFPLKVFQKDGPLLYFDTSNEDDCNWMMMVRPATEHEHQNLTAFQHDNDIYFTTSRDIPPGTELRVWYAAFYAKKMEKPVLKQVTSISNDMCLVVMECDKEGNKVSSKPSTVVFPHKKTKKSSISVADPTVSTPEGGGAAETEPSQWTCKVCSSAFQEPQLLTEHLMSHLEQAKCAPQTGQNEAAAEKVTEAPPADPPVVCDAASASTDSRRKARRGRKIKTAKAETEAPLVAAEEKDPAVERVADTAAEVPPEEVALPSAAEERIMELVLGKMPSTTNSISSVTNRFAHHQNSMSLKRSLILSSRHGIRRKLIKQLGEHKRVYQCSICSKIFQNSSNLSRHIRSHGDKLFKCEECAKLFSRKESLKQHVSYKHSRNEVDSEYRYKCTTCEKAFRIESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEICNKMFYRKDVMLDHQRRHLEGVRRVKREDFEHSTENMVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMDVHKEKGYGCSICNRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTDYMLQKHIQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEILSVKIDDLEQLPETTTIDASSIGIVQPELALEQGELPEGKQHMKAPKRGQKRKQKSGEEEETQVPEDSAFSEYTEKEAEFTGNVGDETNSAVQSIQQVVVTLGDPNVTAPSSSVGLTNITVTPITTAAGTQFTNLQPVAVGHLTAPERQLQLDNSILTVTFDTVSGSAMLHNRQNDIQIQPQPEAANPHSVAHFINLTTLVNSIAPLGNQITEQHPLTWRSVPQTDVLQPPAQPAQQQSGQQQVQAEQQQQMYSY", "length": 1182 }, "evidence": [ { "id": "A0A9J7FYT8", "url": "https://omabrowser.org/oma/group/A0A9J7FYT8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZQ99-1", "protein_name": "PR domain zinc finger protein 15", "gene_name": "Prdm15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRHRPPASGAAQFPERIATRSPDPTPLCTFHRQVSAMAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSKDIPAGTELRVWYAAFYAKKMDKPMLKQACSSVQAAGTPEPSVTVEPERAQWVCKVCSNTFLELQLLNEHLLGHLEQSKSLPAGGQQQEAASEKEPDAPRMEPPTAVESKSMQSATVTKEPKKKPRRGRKPKASKVEQPLVIIKDKEPAEHVAEIITEVPPDEPVNATPDERIMELVLGKLATPTSEASSVPKFLHHPSSTIALKRGLVLSSRHGVRRKLVRQLGEHKRIHQCGTCSKVFQNSSNLSRHVRSHGECAHGDKLFKCEECSKLFSRKESLKQHVSYKHSRNEQVDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKAAKRSHKRKQKPEEEAGAAVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTAPSSSVGLTNITVTPITTAAGTQFTNLQPVAVGHLTNPERQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEATNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAVPQTDVLQPPQAPAAPQQAVQPQVQNEQQQMYSY", "length": 1186 }, "evidence": [ { "id": "A0A9J7FYT8", "url": "https://omabrowser.org/oma/group/A0A9J7FYT8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q8T2-1", "protein_name": "PR domain zinc finger protein 15", "gene_name": "Prdm15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCPPTIWEKGGQVGARWSLRAPEVSAMAEDGSEEIMFIWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPSNLEIRRLDDGAEGVFAVTQLVKRTQFGPFESRRVAKWEKESAFPLKVFQKDGHPVCFDTSNEDDCNWMMLVRPALEPGHQNLTAYQHGSDVYFTTSKDIPAGTELRVWYAAFYAKKMDKPMLKQACSSVQAAGTPEPSVSVEPERGQWVCKVCSNTFLELQLLNEHLLGHLEQAKSLPAGGQQHEAASEKEPDAPRMEPPTAAESKSIQSVMVTKEPKKKPRRGRKPKASKVEQPLVIIKDKEPSEHVAEIITEIPPDEPVSATPDERIMELVLGKLAAPTNEASSVPKFPHHPSSTIALKRGLVLSSRHGVRRKLVRQLGEHKRIHQCGTCSKVFQNSSNLSRHVRSHGECAHGDKLFKCEECSKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGSCGKTFRMESALEFHNCRTDDKTFQCEMCFRFFSTNSNLSKHKKKHGDKKFACEVCSKMFYRKDVMLDHQRRHLDGVRRVKREDLEASGESLVRYKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKKYTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGHGCSICHRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNIREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRKFAQKVNMLKHYKRHTGIKDFMCELCGKTFSERNTMETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRRKHPEVLAVRIDDLDHLPETTTIDASSIGIVQPALGLEQEELAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDTTFSEYPEKEPEFTGSVGDETNSAVQSIQQVVVTLGDPNVTAPSSSVGLTNITVTPITTAAGTQFTNLQPVAVGHLTNPDRQLQLDNSILTVTFDTVSGSAMLHNRQNDVQIHPQPEATNPQSVAHFINLTTLVNSITPLGNQLSEQHPLTWRAVPQTDVLQPPQAPAAPQQAVQPQVQNEQQQMYSY", "length": 1174 }, "evidence": [ { "id": "A0A9J7FYT8", "url": "https://omabrowser.org/oma/group/A0A9J7FYT8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1035, "end_pos": 1037, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1047, "end_pos": 1049, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1125, "end_pos": 1127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FYT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 412, "end_pos": 434, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FYT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYT8" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 195, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 349 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1035, "end_pos": 1037 }, { "start_pos": 1047, "end_pos": 1049 }, { "start_pos": 1125, "end_pos": 1127 }, { "start_pos": 166, "end_pos": 168 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 519, "end_pos": 521 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FZM6-1", "uniprot_ac": "A0A9J7FZM6", "uniprot_id": "A0A9J7FZM6_CRIGR", "mass": { "chemical_mass": 28476.0, "monoisotopic_mass": 28476.0 }, "refseq": { "ac": "XP_007642312", "name": "protein CUSTOS isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642312" }, "gene_names": [ { "name": "CUNH12orf43", "type": "recommended", "evidence": [ { "id": "A0A9J7FZM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6" } ] }, { "name": "CUNH12orf43", "type": "synonym", "evidence": [ { "id": "XP_007642312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642312" } ] } ], "protein_names": [ { "name": "Protein CUSTOS", "type": "recommended", "evidence": [ { "id": "A0A9J7FZM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6/entry#names_and_taxonomy" } ] }, { "name": "protein CUSTOS isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007642312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642312" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613978.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007642312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642312" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH12orf43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6", "locus": {} } ], "crossref": [ { "id": "A0A9J7FZM6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FZM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756058", "url": "https://www.ncbi.nlm.nih.gov/gene/100756058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756058", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756058", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDCTALA", "url": "https://omabrowser.org/oma/group/WDCTALA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FZM6", "url": "https://www.orthodb.org/?gene=A0A9J7FZM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HI65", "url": "https://www.orthodb.org/?gene=G3HI65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14482", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14482", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14482:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14482:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23999", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23999", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007642312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FZM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HI65", "url": "https://www.uniprot.org/uniprotkb/G3HI65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HI65-1", "url": "https://www.uniprot.org/uniprotkb/G3HI65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAPSGTMSDSESSSSSNSDAEELARCREAAMPAWGLEQCPQGAEKPRSDAAGKQVPASSQRSLRREVNQHDEDGNELQTTPEFRAYVAKKLGAMLDSSIAISEVWKKPRKAEVRQVAEEEDGFRLFFTSIPGGHEKEASPKPCRKRQPPSSSSSEDSDEEWQRCREAAVSASDVLQESAIHRPAEVQKEAEKKLKKKAKKEADINLAGATGLKQVKEADTINGDPPSLGIKKKKRKKKAKKAREASPCPPAGRVSVAGPEN", "length": 262, "header": "tr|A0A9J7FZM6-1|A0A9J7FZM6_CRIGR Isoform 1 of Protein CUSTOS OS=Cricetulus griseus OX=10029 GN=CUNH12orf43 PE=3 SV=1 CANONICAL=A0A9J7FZM6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6/entry#A0A9J7FZM6-1", "sequence": { "sequence": "MVAPSGTMSDSESSSSSNSDAEELARCREAAMPAWGLEQCPQGAEKPRSDAAGKQVPASSQRSLRREVNQHDEDGNELQTTPEFRAYVAKKLGAMLDSSIAISEVWKKPRKAEVRQVAEEEDGFRLFFTSIPGGHEKEASPKPCRKRQPPSSSSSEDSDEEWQRCREAAVSASDVLQESAIHRPAEVQKEAEKKLKKKAKKEADINLAGATGLKQVKEADTINGDPPSLGIKKKKRKKKAKKAREASPCPPAGRVSVAGPEN", "length": 262, "header": "tr|A0A9J7FZM6-1|A0A9J7FZM6_CRIGR Isoform 1 of Protein CUSTOS OS=Cricetulus griseus OX=10029 GN=CUNH12orf43 PE=3 SV=1 CANONICAL=A0A9J7FZM6-1" }, "locus": {} }, { "isoform_ac": "G3HI65-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6/entry#G3HI65-1", "sequence": { "sequence": "MVAPSGTMSDSESSSSSNSDAEELARCREAAMPAWGLEQCPQGAEKPRSDAAGKQVPASSQRSLRREVNQHDEDGNELQTTPEFRAYVAKKLGAMLDSSIAISEVWKKPRKAEVRQVAEEEDGFRLFFTSIPGGHEKEASPKPCRKRQPPSSSSEDSDEEWQRCREAAVSASDVLQESAIHRPAEVQKEAEKKLKKKAKKEADINLAGATGLKQVKEADTINGDPPSLGIKKKKRKKKAKKAREASPCPPAGRVSVAGPEN", "length": 261, "header": "tr|G3HI65-1|A0A9J7FZM6_CRIGR Computationally mapped isoform of Protein CUSTOS OS=Cricetulus griseus OX=10029 GN=CUNH12orf43 PE=3 SV=1 CANONICAL=A0A9J7FZM6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HI65", "url": "https://www.uniprot.org/uniprotkb/G3HI65" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HI65", "url": "https://www.uniprot.org/uniprotkb/G3HI65" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756058", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756058", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZRG2-1", "protein_name": "Protein CUSTOS", "gene_name": "C12orf43", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPCGRRRDYSARHAPRRRGFKMAARRDSCGTDSSSDSESSGGAAARFREAAWDCAKQAAVRTEPRGGGFTKDQRQAARPSLRREVNDHDEDGNELQTTPEFRAHVAKKLGAMLDSFITVLKDSSGPSPACVQQSDCGDDGFRLFSSSVPGDCGQSEQSPAPRRRRPPSSSDSDSDQEWQKYQEAAVSAADILKQSAFPELSQDSSQNMCQGYVEHRQKKKKKKKIKGENKTEEKIIDPAERDQVSKDLPWLVSANGQHKREDSNHTDNTVSPGAVMKKKKKKKKERE", "length": 287 }, "evidence": [ { "id": "A0A9J7FZM6", "url": "https://omabrowser.org/oma/group/A0A9J7FZM6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9TXA0-1", "protein_name": "Protein CUSTOS", "gene_name": "C17H12orf43", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSDLESSSSSSSDEEELERCREAALPAWGLEQRPRGPEKPGVDATNAKLPANQPSLRHKVDEHEQDGNELQTTPEFRAHVAKKLGALLDRSSLLCSGSLVVASGGSSLLSSITISEIVKEPRKSEVQQGALEDDGFRLFFTSIPGGPEKEAAPQPCRKRLPSSSSSDDGDEELRRCREAAVSASDILQESAIHGHVSVEKKKKRKLKKKAKKEDSADVAAAATSKAAVGRQEKESAQLNGDQAPPGTKKKKRKKKTKKASEASPSPPTKSAAAVPSN", "length": 277 }, "evidence": [ { "id": "A0A9J7FZM6", "url": "https://omabrowser.org/oma/group/A0A9J7FZM6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RJG8-1", "protein_name": "Protein CUSTOS", "gene_name": "C12orf43", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSYLESSSSSSSDAEELERCREAAMPAWGLEQRPRGLEKPKAGAANTQLPTTQPSLRHKVDEHEQDGNELQTTPEFRAHVAKKLGALLDSSITISEVVKEPRKAEVRRGTPEDDGFRLFFTSIPGASEKEAAPQPRRKRLPSSSSSEDGDEELQRCREAAVSASDILQESAIHGPVSVEEKAKKKKRKLKKKAKKEASASVAAAATVTTTGKAAVGKQSKESAELNGAQVPLGTKKKKRKKKAKRAGEAAPSPPAKSAAATPVHRVLPVGTGPN", "length": 274 }, "evidence": [ { "id": "A0A9J7FZM6", "url": "https://omabrowser.org/oma/group/A0A9J7FZM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3UY34-1", "protein_name": "Protein CUSTOS", "gene_name": "Custos", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVAPSGAMSDSENSSSSSSDAEELARCREAATPAWGLEQRPGAAERPEAGAADKQAPTPQPSRRHEVNQHEEDGNDLRTTPEFRAHVAKKLGALLDSSIAIAEVWKKSQKAKMQQVAKEEDGFRLFFTSIPGGHKKEASPRPCRKRQPPSSSEDSDEELQRCREAAVSASDILQESAIHCPAKAEEKKKLKKKAKKKVDNADLAAAPGLEQVKEAGVVNGDPVSLGIQKKRKKKAKKSREAPLCPPAECAAAKPEN", "length": 256 }, "evidence": [ { "id": "A0A9J7FZM6", "url": "https://omabrowser.org/oma/group/A0A9J7FZM6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5I034-1", "protein_name": "Protein CUSTOS", "gene_name": "Custos", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVAPSGAMSDSESSSSDSSDAEELARCREAATPAWGLEQRPREAERPAAGTADTQAPAPQPSRRREVNQHDEDGNELQTTPEFRAYVAKKLGALLDSSIAIAEVWKKTQQARLQQEAKEQQEAKEQQAAKEEQAAKKEEDGFRLFFTSVPGGHEKEASPRPCRKRQPPSSSEDSDEELQRCREAAVSASDILQESAIHCPAKVEKEAEKKKLKKKAKKKADADLAAATGLEQVKEAGSVNGDPVLSGTKKKKKKKAKKAREASLCPPAECAAAEPKN", "length": 277 }, "evidence": [ { "id": "A0A9J7FZM6", "url": "https://omabrowser.org/oma/group/A0A9J7FZM6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96C57-1", "protein_name": "Protein CUSTOS", "gene_name": "CUSTOS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPSGTVSDSESSNSSSDAEELERCREAAMPAWGLEQRPHVAGKPRAGAANSQLSTSQPSLRHKVNEHEQDGNELQTTPEFRAHVAKKLGALLDSFITISEAAKEPAKAKVQKVALEDDGFRLFFTSVPGGREKEESPQPRRKRQPSSSSEDSDEEWRRCREAAVSASDILQESAIHSPGTVEKEAKKKRKLKKKAKKVASVDSAVAATTPTSMATVQKQKSGELNGDQVSLGTKKKKKAKKASETSPFPPAKSATAIPAN", "length": 262 }, "evidence": [ { "id": "A0A9J7FZM6", "url": "https://omabrowser.org/oma/group/A0A9J7FZM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear envelope", "id": "GO:0005635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005635", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6" } ], "pmid": "" }, { "name": "Spemann organizer formation", "id": "GO:0060061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060061", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FZ58-1", "uniprot_ac": "A0A9J7FZ58", "uniprot_id": "A0A9J7FZ58_CRIGR", "mass": { "chemical_mass": 27853.0, "monoisotopic_mass": 27853.0 }, "refseq": { "ac": "XP_007642316", "name": "corrinoid adenosyltransferase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642316" }, "gene_names": [ { "name": "Mmab", "type": "recommended", "evidence": [ { "id": "A0A9J7FZ58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58" } ] }, { "name": "Mmab", "type": "synonym", "evidence": [ { "id": "XP_007642316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642316" } ] } ], "protein_names": [ { "name": "Corrinoid adenosyltransferase MMAB", "type": "recommended", "evidence": [ { "id": "A0A9J7FZ58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58/entry#names_and_taxonomy" } ] }, { "name": "ATP:co(I)rrinoid adenosyltransferase MMAB", "type": "synonym", "evidence": [ { "id": "A0A9J7FZ58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58/entry#names_and_taxonomy" } ] }, { "name": "corrinoid adenosyltransferase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007642316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642316" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613978.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007642316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642316" } ] }, { "annotation": "Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion. Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP-binding to MMAB and gated by MMAA.", "evidence": [ { "database": "UniProtKB", "id": "G3HI80", "url": "https://www.uniprot.org/uniprotkb/G3HI80#function" }, { "database": "UniProtKB", "id": "ARBA00056747", "url": "https://www.uniprot.org/uniprotkb/ARBA00056747#function" }, { "database": "UniProtKB", "id": "A0A9J7FZ58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mmab", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58", "locus": {} } ], "crossref": [ { "id": "A0A9J7FZ58", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FZ58", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751940", "url": "https://www.ncbi.nlm.nih.gov/gene/100751940", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751940", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751940", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HQACTVV", "url": "https://omabrowser.org/oma/group/HQACTVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FZ58", "url": "https://www.orthodb.org/?gene=A0A9J7FZ58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HI80", "url": "https://www.orthodb.org/?gene=G3HI80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12213:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12213:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007642316", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642316", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "56796", "url": "https://www.rhea-db.org/rhea/56796", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FZ58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ58-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HI80", "url": "https://www.uniprot.org/uniprotkb/G3HI80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HI80-1", "url": "https://www.uniprot.org/uniprotkb/G3HI80-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVWVFGGRLGLRRHLDVCRLLCPRFQSRGPQSEEDGNRPKSSSKAHKIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFAMELITEKGHTFAKELQKIQCTLQDVGSALATPRSSAREAHLKYTTFKEGPIVELEQWIDKYSSQLPPLTAFILPSGGKSSSALHFCRAVCRRAERRLEADSPAHEGTKTTLVGTKASLPSAYLLCLLLHWPGHVMSVQVWCLLSKWEKRMQMWPSF", "length": 249, "header": "tr|A0A9J7FZ58-1|A0A9J7FZ58_CRIGR Isoform 1 of Corrinoid adenosyltransferase MMAB OS=Cricetulus griseus OX=10029 GN=Mmab PE=3 SV=1 CANONICAL=A0A9J7FZ58-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZ58-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58/entry#A0A9J7FZ58-1", "sequence": { "sequence": "MAVWVFGGRLGLRRHLDVCRLLCPRFQSRGPQSEEDGNRPKSSSKAHKIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFAMELITEKGHTFAKELQKIQCTLQDVGSALATPRSSAREAHLKYTTFKEGPIVELEQWIDKYSSQLPPLTAFILPSGGKSSSALHFCRAVCRRAERRLEADSPAHEGTKTTLVGTKASLPSAYLLCLLLHWPGHVMSVQVWCLLSKWEKRMQMWPSF", "length": 249, "header": "tr|A0A9J7FZ58-1|A0A9J7FZ58_CRIGR Isoform 1 of Corrinoid adenosyltransferase MMAB OS=Cricetulus griseus OX=10029 GN=Mmab PE=3 SV=1 CANONICAL=A0A9J7FZ58-1" }, "locus": {} }, { "isoform_ac": "G3HI80-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58/entry#G3HI80-1", "sequence": { "sequence": "MAVWVFGGRLGLRRHLDVCRLLCPRFQSRGPQSEEDGNRPKSSSKAHKIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFAMELITEKGHTFAKELQKIQCTLQDVGSALATPRSSAREAHLKYTTFKEGPIVELEQWIDKYSSQLPPLTAFILPSGGKSSSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTIARYAAMKEGSQEKIYKKSDE", "length": 237, "header": "tr|G3HI80-1|A0A9J7FZ58_CRIGR Computationally mapped isoform of Corrinoid adenosyltransferase MMAB OS=Cricetulus griseus OX=10029 GN=Mmab PE=3 SV=1 CANONICAL=A0A9J7FZ58-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HI80", "url": "https://www.uniprot.org/uniprotkb/G3HI80" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HI80", "url": "https://www.uniprot.org/uniprotkb/G3HI80" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751940", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751940", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZLS8-1", "protein_name": "Metabolism of cobalamin associated B", "gene_name": "MMAB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLRRAAAAAAGSGLGRPLWVVAGRGQSGEAGSPEGGPPSARSPRIYTRTGDEGFSSTFTGERRPKGDRIFEALGTTDELSSAIGLASELSSEKGHAFVEQLHKVQCMLQDVGSNIATPLSSAREAHLKRTSFSEEPILELEKWIDRYSEQLPPLRAFILPCGSLSTSRGGRSKRGQIFKQTERLPLRFGTLCCNEGREGRENIYKAKTITGSWDVYAVDLGKLNPAERFSRHGWQREQAQIGNVSCQRLPVNMMGTLFINAVRNTAVLSTRPCSDTVVLVSELLFALDQS", "length": 290 }, "evidence": [ { "id": "A0A9J7FZ58", "url": "https://omabrowser.org/oma/group/A0A9J7FZ58/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0L5G5-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "Mmab", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVWTFGGRLGLRGRLGGCRLLCPRFQSFGPQGGEDGDRPQPSSKAAKVLKIYTKTGDKGLSSTFTGERRPKDDQVFEALGTTDELSSAIGFAMELITEKGHTFAEELRKIQCTLQDVGSALATPRSSAREAHLKHTAFQEEPILELEQWIDKYSSQLPPLTAFILPSGGKSSSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNSSGRAEPGAGATCRLLGWRSSPGLSDYLFTVARYAAMKEGSQEKIYKKRDV", "length": 259 }, "evidence": [ { "id": "A0A9J7FZ58", "url": "https://omabrowser.org/oma/group/A0A9J7FZ58/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2BGN0-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "mmab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSLVTRSTSLHRVLRLGTCMNIKQMRVCGDRGRYASSTSEENRRIPKIYTKTGDKGFSSTFTGERRPKEDHIFDALGTTDELSSAIGLAREFCIDSGHSFTDQLEKVQCVLQDVGSNIATPRSSARESHITKTKFSSQSVSELEKWIDSFTEELPPLTSFILPSGGKSSAALHVARAVCRRAERCVAPVVRSGETDPEVAKYLNRLSDYLFTVARYAAMKDGNAETIYKRQE", "length": 233 }, "evidence": [ { "id": "A0A9J7FZ58", "url": "https://omabrowser.org/oma/group/A0A9J7FZ58/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54W51-1", "protein_name": "Cobalamin adenosyltransferase-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIKISNFRNNNNNNILIINRFFSSKIYTKTGDKGTSALFNGERRKKDDQIFQALGSVDELSSQLGLSKEHLIVLRKEINNEKKELANRVIDEIEQIQCLLLDIGSHIATPSYSEEQFQKRSQFNDFHTTQLENWVDHYTNNHLAPLKNFILPGGGLTSASLHVCRSVCRRSERELITMTNLENEYENNNNNNNNNNNNNNNNNNNEISSPVLRFINRLSDYLFTIARISNKIEGGEESIYRRPSESLSSNNKNNNNSNSSNNNNNNNNNNNDNNKYQRILEKHSTIQD", "length": 291 }, "evidence": [ { "id": "A0A9J7FZ58", "url": "https://omabrowser.org/oma/group/A0A9J7FZ58/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q96EY8-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "MMAB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVCGLGSRLGLGSRLGLRGCFGAARLLYPRFQSRGPQGVEDGDRPQPSSKTPRIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMKNDPSAESEGL", "length": 250 }, "evidence": [ { "id": "A0A9J7FZ58", "url": "https://omabrowser.org/oma/group/A0A9J7FZ58/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D273-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "Mmab", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVWLFGGRLGLRGRLSACRLLCPRFQSRGPQGGEDGDRLQPSSTAAKIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFAMELVTEKGHMFAEELQKIQCMLQDVGSALATPRSSAREAHLKHTAFQEGPVLELERWIDKYSSQLPPLKAFILPSGGKSSSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTVARYAAMKEGSQEKIYKKHDV", "length": 237 }, "evidence": [ { "id": "A0A9J7FZ58", "url": "https://omabrowser.org/oma/group/A0A9J7FZ58/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58" } ], "pmid": "" }, { "name": "cobalamin binding", "id": "GO:0031419", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031419", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58" } ], "pmid": "" }, { "name": "corrinoid adenosyltransferase activity", "id": "GO:0008817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008817", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cobalamin metabolic process", "id": "GO:0009235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009235", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "56796", "name": "", "equation": "cob(I)alamin-[corrinoid adenosyltransferase] + ATP = apo-[corrinoid adenosyltransferase] + adenosylcob(III)alamin + triphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "56796", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56796" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FZ58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ58" }, { "id": "PF01923", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cobalamin adenosyltransferase-like", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 191, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G0D9-1", "uniprot_ac": "A0A9J7G0D9", "uniprot_id": "A0A9J7G0D9_CRIGR", "mass": { "chemical_mass": 31165.0, "monoisotopic_mass": 31165.0 }, "refseq": { "ac": "XP_027272789", "name": "B-cell receptor-associated protein 29 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272789" }, "gene_names": [ { "name": "Bcap29", "type": "recommended", "evidence": [ { "id": "A0A9J7G0D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9" } ] }, { "name": "Bcap29", "type": "synonym", "evidence": [ { "id": "XP_027272789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272789" } ] } ], "protein_names": [ { "name": "B-cell receptor-associated protein", "type": "recommended", "evidence": [ { "id": "A0A9J7G0D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9/entry#names_and_taxonomy" } ] }, { "name": "B-cell receptor-associated protein 29 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027272789", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272789" } ] }, { "name": "BCR-associated protein", "type": "synonym", "evidence": [ { "id": "A0A9J7G0D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272789", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272789" } ] }, { "annotation": "Plays a role in the export of secreted proteins in the ER.", "evidence": [ { "database": "UniProtKB", "id": "G3I7S8", "url": "https://www.uniprot.org/uniprotkb/G3I7S8#function" }, { "database": "UniProtKB", "id": "RU367026", "url": "https://www.uniprot.org/uniprotkb/RU367026#function" }, { "database": "UniProtKB", "id": "A0A9J7G0D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9#function" }, { "database": "UniProtKB", "id": "A0A9J7GY77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY77#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bcap29", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9", "locus": {} } ], "crossref": [ { "id": "100754548", "url": "https://www.ncbi.nlm.nih.gov/gene/100754548", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754548", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754548", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FMARFWN", "url": "https://omabrowser.org/oma/group/FMARFWN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G0D9", "url": "https://www.orthodb.org/?gene=A0A9J7G0D9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3I7S8", "url": "https://www.orthodb.org/?gene=G3I7S8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12701", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12701", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12701:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12701:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272789", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272789", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G0D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY77-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I7S8", "url": "https://www.uniprot.org/uniprotkb/G3I7S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I7S8-1", "url": "https://www.uniprot.org/uniprotkb/G3I7S8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTIQWAAVASFLYAEIGLILIFCLPFIPPQRWQKIFSFSVWSKIASFWNKAFLTIIILLIVLFLDAVREVRKYSSTQVTEKSSAGRPSAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVSLITQLAKEISNKAVLKIQAENTNKAAKKFMEENEKLKWVLKNNGKDEEQILETENKKLVEDQEKLKTELKKASDVGGVVWEGITGMASLSLWPQCALCLLFGLNVSVKMFLPPCLCFAIMDSNPQKRPFKGTKRCGNYEDAVRETFKRI", "length": 271, "header": "tr|A0A9J7G0D9-1|A0A9J7G0D9_CRIGR Isoform 1 of B-cell receptor-associated protein OS=Cricetulus griseus OX=10029 GN=Bcap29 PE=3 SV=1 CANONICAL=A0A9J7G0D9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G0D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9/entry#A0A9J7G0D9-1", "sequence": { "sequence": "MTIQWAAVASFLYAEIGLILIFCLPFIPPQRWQKIFSFSVWSKIASFWNKAFLTIIILLIVLFLDAVREVRKYSSTQVTEKSSAGRPSAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVSLITQLAKEISNKAVLKIQAENTNKAAKKFMEENEKLKWVLKNNGKDEEQILETENKKLVEDQEKLKTELKKASDVGGVVWEGITGMASLSLWPQCALCLLFGLNVSVKMFLPPCLCFAIMDSNPQKRPFKGTKRCGNYEDAVRETFKRI", "length": 271, "header": "tr|A0A9J7G0D9-1|A0A9J7G0D9_CRIGR Isoform 1 of B-cell receptor-associated protein OS=Cricetulus griseus OX=10029 GN=Bcap29 PE=3 SV=1 CANONICAL=A0A9J7G0D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GY77-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9/entry#A0A9J7GY77-1", "sequence": { "sequence": "MTIQWAAVASFLYAEIGLILIFCLPFIPPQRWQKIFSFSVWSKIASFWNKAFLTIIILLIVLFLDAVREVRKYSSTQVTEKSSAGRPSAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVSLITQLAKEISNKAVLKIQAENTNKAAKKFMEENEKLKWVLKNNGKDEEQILETENKKLVEDQEKLKTELKKASDALLKAQNDVVTMKMQSERLSKEYDRLLKEHSELQVTELERASKEPFGKRQKESPVN", "length": 252, "header": "tr|A0A9J7GY77-1|A0A9J7GY77_CRIGR Computationally mapped isoform of B-cell receptor-associated protein OS=Cricetulus griseus OX=10029 GN=Bcap29 PE=3 SV=1 CANONICAL=A0A9J7G0D9-1" }, "locus": {} }, { "isoform_ac": "G3I7S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9/entry#G3I7S8-1", "sequence": { "sequence": "MTIQWAAVASFLYAEIGLILIFCLPFIPPQRWQKIFSFSVWSKIASFWNKAFLTIIILLIVLFLDAVREVRKYSSTQVTEKSSAGRPSAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVSLITQLAKEISNKAVLKIQAENTNKAAKKFMEENEKLKWVLKNNGKDEEQILETENKKLVEDQEKLKTELKKASDALLKAQNDVVTMKMQSERLSKEYDRLLKEHSELQNRLEKDKKKVL", "length": 241, "header": "tr|G3I7S8-1|A0A9J7G0D9_CRIGR Computationally mapped isoform of B-cell receptor-associated protein OS=Cricetulus griseus OX=10029 GN=Bcap29 PE=3 SV=1 CANONICAL=A0A9J7G0D9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I7S8", "url": "https://www.uniprot.org/uniprotkb/G3I7S8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I7S8", "url": "https://www.uniprot.org/uniprotkb/G3I7S8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754548", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754548", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1V4F7-1", "protein_name": "B-cell receptor-associated protein", "gene_name": "BCAP29", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTLQWAAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFSVWGKIATFWNKAFLTIIVLLIVLFLDAVREVRKYSSAHAIERSSASRPAAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKELSNKGVLKSQAESTNKAAKKFMEENERLKRLLKNYGKEEDHILEEENKKLVEDKEKLQTELKKVSDALSKAQNDVMTMKVQSERLSKEYDLLLKEHSELQDHARKGSKKGL", "length": 241 }, "evidence": [ { "id": "A0A9J7G0D9", "url": "https://omabrowser.org/oma/group/A0A9J7G0D9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1C310-1", "protein_name": "Endoplasmic reticulum transmembrane protein", "gene_name": "BCAP29", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTVQWTAVAAFLYGEVGVLLVLCLPFISPLRWQKIFMIPLWSKMAVFWNKMFLTIIVLLIILFLDAVREVKKYSAIQLNEKVANVNANAIDHIQMKLFRSQRNLYISGFSLFLWLVLRRTVTLLTQLAKGMASHAALETQVNDATEAAKKYMAENERLQEALNEKGSGENKEMAETTNGMLRKEIGQLKAELQKTSNALHKANNEVAAVKKQSEGLRREYDHLMKEYERLQNASSEAEDKKDL", "length": 243 }, "evidence": [ { "id": "A0A9J7G0D9", "url": "https://omabrowser.org/oma/group/A0A9J7G0D9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F7F288-1", "protein_name": "B-cell receptor-associated protein", "gene_name": "Bcap29", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTIQWAAVASFLYAEIGLILIFCLPFISPQRWHKIFSFSVWTKIASFWNKAFLTIIILLVVLFLDAVREVKKYSSINVVEKNSASRPAAYEQAQMRLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKEITNKGVLKIQAENTNKAAKKFMEENERLKLVLKNNDNTEEHVLETENKKLVEDKERLKTELKKASDALFKAQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKENKKGL", "length": 241 }, "evidence": [ { "id": "A0A9J7G0D9", "url": "https://omabrowser.org/oma/group/A0A9J7G0D9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61334-1", "protein_name": "B-cell receptor-associated protein 29", "gene_name": "Bcap29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTIQWAAVASFLYAEIGLILLFCLPFIPPQRWQKIFSFSVWGKIASFWNKAFLTIIILLIILFLDAVREVRKYSSTNVVEKNSAIRPSAFEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKEIANKGVLKIQAENTNKAAKKFMEENEKLKLGLRNDNAEEHLLEAENKKLIESKENLKTELKKASDALLKAQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLEKEKKKGL", "length": 240 }, "evidence": [ { "id": "A0A9J7G0D9", "url": "https://omabrowser.org/oma/group/A0A9J7G0D9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9" } ], "pmid": "" }, { "name": "endoplasmic reticulum to Golgi vesicle-mediated transport", "id": "GO:0006888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006888", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D9" } ], "pmid": "" }, { "name": "protein localization to endoplasmic reticulum exit site", "id": "GO:0070973", 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"monoisotopic_mass": 131025.0 }, "refseq": { "ac": "XP_027240346", "name": "tectonin beta-propeller repeat-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240346" }, "gene_names": [ { "name": "Tecpr1", "type": "recommended", "evidence": [ { "id": "A0A9J7FWV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9" } ] }, { "name": "Tecpr1", "type": "synonym", "evidence": [ { "id": "XP_027240346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240346" } ] } ], "protein_names": [ { "name": "Tectonin beta-propeller repeat-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7FWV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9/entry#names_and_taxonomy" } ] }, { "name": "tectonin beta-propeller repeat-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027240346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240346" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615470.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027240346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240346" } ] }, { "annotation": "Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation.", "evidence": [ { "database": "UniProtKB", "id": "G3IC78", "url": "https://www.uniprot.org/uniprotkb/G3IC78#function" }, { "database": "UniProtKB", "id": "ARBA00059274", "url": "https://www.uniprot.org/uniprotkb/ARBA00059274#function" }, { "database": "UniProtKB", "id": "A0A9J7FWV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9#function" }, { "database": "UniProtKB", "id": "A0A9J7FZ38", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ38#function" }, { "database": "UniProtKB", "id": "A0A9J7JX20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JX20#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tecpr1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9", "locus": {} } ], "crossref": [ { "id": "A0A9J7FWV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FWV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13300", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13300", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769434", "url": "https://www.ncbi.nlm.nih.gov/gene/100769434", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006624", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006624", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769434", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769434", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPMQISR", "url": "https://omabrowser.org/oma/group/CPMQISR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FWV9", "url": "https://www.orthodb.org/?gene=A0A9J7FWV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3IC78", "url": "https://www.orthodb.org/?gene=G3IC78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23250:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23250:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06398", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06398", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027240346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240346", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FWV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ38", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ38-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JX20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JX20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JX20-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JX20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3IC78", "url": "https://www.uniprot.org/uniprotkb/G3IC78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3IC78-1", "url": "https://www.uniprot.org/uniprotkb/G3IC78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTSVLWAVDLFGRVYTLSTAGQYWELCKDVQMEFKRVSAATQCCWGIACDNQVYLYVCSSDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWSWSDVSGLQHRPLDGVALPSPHWEWESDWYVDENFGGEPTEKGGWTYAMDFPATYTREKKWNSCVRRRKWIRYRRYKSRDTWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHPNPEGSSWSLVDTPGEVVQISCGPHDLIWATLWEGQALVREGICRNNPKGSSWSIVEPPGSENGIMHVSVGVSVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQGVTPTELSGKTWKAIIVGRESDRSHSGSSSSLLSAGCFFGDEVRGSGTESAPSDTDASSEVERQGPEQLLPRESVDHSRNLKGNLSKGPETSGSTEQTMESACPDDSKGKAPEASGIDECHGPASTPAELPWTNIDLKEPKRVSSQPSTGFPETTGLSSLGLFPLGMEEPYGADDHPLWAWVSGGGCSVEACSVLKWFTVQSGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYMIHEEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVHGRPSPQAIWSVTCKGDIFVSEPSPDLEAREHLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRYMWSDATGLQECTKAGTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYASDFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPIALSDVSIIPEGADVDGRGHHIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGDFSITGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSSWEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQSWDYGIGGGWDHISVRANATMVPRNMSREQEAHVQGPVYC", "length": 1172, "header": "tr|A0A9J7FWV9-1|A0A9J7FWV9_CRIGR Isoform 1 of Tectonin beta-propeller repeat-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Tecpr1 PE=3 SV=1 CANONICAL=A0A9J7FWV9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FWV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9/entry#A0A9J7FWV9-1", "sequence": { "sequence": "MPTSVLWAVDLFGRVYTLSTAGQYWELCKDVQMEFKRVSAATQCCWGIACDNQVYLYVCSSDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWSWSDVSGLQHRPLDGVALPSPHWEWESDWYVDENFGGEPTEKGGWTYAMDFPATYTREKKWNSCVRRRKWIRYRRYKSRDTWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHPNPEGSSWSLVDTPGEVVQISCGPHDLIWATLWEGQALVREGICRNNPKGSSWSIVEPPGSENGIMHVSVGVSVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQGVTPTELSGKTWKAIIVGRESDRSHSGSSSSLLSAGCFFGDEVRGSGTESAPSDTDASSEVERQGPEQLLPRESVDHSRNLKGNLSKGPETSGSTEQTMESACPDDSKGKAPEASGIDECHGPASTPAELPWTNIDLKEPKRVSSQPSTGFPETTGLSSLGLFPLGMEEPYGADDHPLWAWVSGGGCSVEACSVLKWFTVQSGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYMIHEEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVHGRPSPQAIWSVTCKGDIFVSEPSPDLEAREHLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRYMWSDATGLQECTKAGTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYASDFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPIALSDVSIIPEGADVDGRGHHIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGDFSITGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSSWEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQSWDYGIGGGWDHISVRANATMVPRNMSREQEAHVQGPVYC", "length": 1172, "header": "tr|A0A9J7FWV9-1|A0A9J7FWV9_CRIGR Isoform 1 of Tectonin beta-propeller repeat-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Tecpr1 PE=3 SV=1 CANONICAL=A0A9J7FWV9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZ38-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9/entry#A0A9J7FZ38-1", "sequence": { "sequence": "MPTSVLWAVDLFGRVYTLSTAGQYWELCKDVQMEFKRVSAATQCCWGIACDNQVYLYVCSSDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWSWSDVSGLQHRPLDGVALPSPHWEWESDWYVDENFGGEPTEKGGWTYAMDFPATYTREKKWNSCVRRRKWIRYRRYKSRDTWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHPNPEGSSWSLVDTPGEVVQISCGPHDLIWATLWEGQALVREGICRNNPKGSSWSIVEPPGSENGIMHVSVGVSVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQGVTPTELSGKTWKAIIVGRESDRSHSGSSSSLLSAGCFFGDEVRGSGTESAPSDTDASSEVERQGPEQLLPRESVDHSRNLKGNLSKGPETSGSTEQTMESACPDDSKGKAPEASGIDECHGPASTPAELPWTNIDLKEPKRVSSQPSTGFPETTGLSSLGLFPLGMEEPYGADDHPLWAWVSGGGCSVEACSVLKWFTVQSGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYMIHEEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVHGRPSPQAIWSVTCKGDIFVSEPSPDLEAREHLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRYMWSDATGLQECTKAGTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYASDFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPIALSDVSIIPEGADVDGRGHHIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGE", "length": 1028, "header": "tr|A0A9J7FZ38-1|A0A9J7FZ38_CRIGR Computationally mapped isoform of Tectonin beta-propeller repeat-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Tecpr1 PE=3 SV=1 CANONICAL=A0A9J7FWV9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JX20-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9/entry#A0A9J7JX20-1", "sequence": { "sequence": "MRILEGSPPRKGGGHTLWTSQPPTLERRSGIHAFGGGSGSGIGDTNPGTPGPRFPQRMTPRNSLTLSMTCLWEGGRSQRNLWAACQCGLCPCRERCGTERMSATPTQKAPPGLLWIPQGRWFKSAVDPMTLYGPPSGRGKPWSEKESAGTTQKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQGVTPTELSGKTWKAIIVGRESDRSHSGSSSSLLSAGCFFGDEVRGSGTESAPSDTDASSEVERQGPEQLLPRESVDHSRNLKGNLSKGPETSGSTEQTMESACPDDSKGKAPEASGIDECHGPASTPAELPWTNIDLKEPKRVSSQPSTGFPETTGLSSLGLFPLGMEEPYGADDHPLWAWVSGGGCSVEACSVLKWFTVQSGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYMIHEEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVHGRPSPQAIWSVTCKGDIFVSEPSPDLEAREHLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRYMWSDATGLQECTKAGTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYASDFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPIALSDVSIIPEGADVDGRGHHIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGDFSITGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSSWEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQSWDYGIGGGWDHISVRANATMVPRNMSREQEAHVQGPVYC", "length": 1014, "header": "tr|A0A9J7JX20-1|A0A9J7JX20_CRIGR Computationally mapped isoform of Tectonin beta-propeller repeat-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Tecpr1 PE=3 SV=1 CANONICAL=A0A9J7FWV9-1" }, "locus": {} }, { "isoform_ac": "G3IC78-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9/entry#G3IC78-1", "sequence": { "sequence": "MPTSVLWAVDLFGRVYTLSTAGQYWELCKDVQMEFKRVSAATQCCWGIACDNQVYLYVCSSDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWSWSDVSGLQHRPLDGVALPSPHWEWESDWYVDENFGGEPTEKGGWTYAMDFPATYTREKKWNSCVRRRKWIRYRRYKSRDTWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHPNPEGSSWSLVDTPGEVVQISCGPHDLIWATLWEGQALVREGICRNNPKGSSWSIVEPPGSENGIMHVSVGVSVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQGVTPTELSGKTWKAIIVGRESDRSHSGSSSSLLSAGCFFGDEVRGSGTESAPSDTDASSEVERQGPEQLLPRESVDHSRNLKGNLSKGPETSGSTEQTMESACPDDSKGKAPEASGIDECHGPASTPAELPWTNIDLKEPKRVSSQPSTGFPETTGLSSLGLFPLGMEEPYGADDHPLWAWVSGGGCSVEACSVLKWFTVQSGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYMIHEEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVHGRPSPQAIWSVTCKGDIFVSEPSPDLEAREHLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRYMWSDATGLQECTKAGTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYASDFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPIALSDVSIIPEGADVDGRGHHIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSSWEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQSWDYGIGGGWDHISVRANATMVPRNMSREQEAHVQGPVYC", "length": 1166, "header": "tr|G3IC78-1|A0A9J7FWV9_CRIGR Computationally mapped isoform of Tectonin beta-propeller repeat-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Tecpr1 PE=3 SV=1 CANONICAL=A0A9J7FWV9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 363, "start_aa": "Thr", "end_pos": 363, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr363", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 486, "start_aa": "Thr", "end_pos": 486, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr486", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3IC78", "url": "https://www.uniprot.org/uniprotkb/G3IC78" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3IC78", "url": "https://www.uniprot.org/uniprotkb/G3IC78" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769434", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769434", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3ZBA0-1", "protein_name": "Tectonin beta-propeller repeat-containing protein 1", "gene_name": "Tecpr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTSMLWAVDLFGRVYTLSTAGQYWELCKDVQLEFKRVSAATQCCWGIACDNQVYLYVCSSDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWSWSDVSGLQHRPLDGVALPSPYWEWESDWYVDENFGGEPTEKGGWTYAMDFPATYTRDKKWNSCVRRRKWIRYRRYKSRDTWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYRENVSHPNPEGSSWSLVDTPGEVVQISCGPHDLIWATLWEGQALVREGICRNNPKGNSWSIVEPPGSENGIMHVSAGVSVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQGVTPSELSGKTWKAIVVGRESDRSHSGSSSSLLSAGCFFGEEVRGSGTESAPSDTDASSEVERQGPERSLPKESLDNSRNLKGSSSKGHESTRNTEDPMENACLAEGQAKAPKTSGPDECHGPAPTPAELPWTNIDLKEPKKASNQPAAGFPETSGLSSLGLFPMGMEEPYGADDHPLWAWVSGGGCAVEAGSALKWFTVQSGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYVVHEEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAATTEQDMNDWLTLLSLSCCESRKVHGRPSLQAIWSVTCKGDIFVSEPSPDLEAHEHLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRYMWSDVTGLQECTKAGTKPPSLQWTWVSDWYVDFSVLGGTDQEGWQYASDFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPIALSDVSIIPESADANGRGHNIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSSWEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQGWDYGIGGGWDHISVRANATRAPRNMSRDQEAHGPGPVCC", "length": 1166 }, "evidence": [ { "id": "A0A9J7FWV9", "url": "https://omabrowser.org/oma/group/A0A9J7FWV9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z6L1-1", "protein_name": "Tectonin beta-propeller repeat-containing protein 1", "gene_name": "TECPR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1165 }, "evidence": [ { "id": "A0A9J7FWV9", "url": "https://omabrowser.org/oma/group/A0A9J7FWV9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80VP0-1", "protein_name": "Tectonin beta-propeller repeat-containing protein 1", "gene_name": "Tecpr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1166 }, "evidence": [ { "id": "A0A9J7FWV9", "url": "https://omabrowser.org/oma/group/A0A9J7FWV9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VWB0-1", "protein_name": "Tectonin beta-propeller repeat-containing protein", "gene_name": "Pex23", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPSFYLFAASSEGRVYTLSTNSGAWRELPYLGLEFKKICAVPNFLWAIGGDRQVYVHVHGLDVPIRIREESYENERWLPIEGFSKTLLPTDRYRYSSADGSVERGVDKIRLPSMAWQWDGDWHLDLELDGQPLTEDGWMYALDFPATYSAKKSWNSYVRRRKWVRYRRYAALNSWCAVAPLHKDPTQEPFIDVAIGGTCVPNAPAGTLCVWAITAHGRAMFRTGVSKTAPEGLRWTAVPTPTGSELAQISVGPTGLVWAVLHNGRVIVRTGVTRDNLVGDSWLDVKTPVAASSLRIVHVSVGTDAVWCVTNDHHAWFRRGVKGEAAGISEDSAIGKGWVEMVGNISMVSVAANDQVFAIGAADRCLYHRSGVTSADPTGKKWRLIQCPMQISRTSSSLSIVSRKSGGSSSTPGSKHQSFSNLYSKEKEKGVVETCAVIETVLNSSTGSCSSNGGPPGLLKNERWKLSADSPPTIGSLNLNDRHKQRTAALRETSHASSAPAADVVEVVTGKFETQLRNPRAWSPVRSVGSVVGTEAHPESDSTVFESDSTHHGSDVFLGEDDDHTGSQFWTECGILWSCVASGAVTVDASNMPNWFNEQTSDSKVDVNANWRKDIVNKLQRRQEKLAKLQTVAKFEKAVELSSWVKSADARYQRPGGEFEDCIIELEWVSSGSGTDTNSSENSRSGDSGTFTVLSPDGAATKIQFPLSDITCVQCCSEAGAPRIAIHAPHLPVNCSPVKLQFSSDSEMEDWLSHLSSVCSQINTMVGKPAGNAIWITSELGDVFVFDPANMKAHQTSEPSEGYVEKMDVSTCETPYYNTLYNGMPCGTELEISGCVYDDADQIRFDLQSHSAVKVQPHRVEKHRVIALHLNPRFNERTTVLNSMKESEWLDEIRNDKMAFAPGATFSLKIRALQDHYLIIVNNAVYTDYKYRIDPESVTRLYVSGRIKLFNVLYRCPSLIVSMERMHWRQMGGHIKRIFNSGVDVVWGISCDNTGWVYNGGWGGMFLKGLEGSGKINPMIDTHTYYVYENQRWNPISGFTAKSLPTDRHMWSDATGRQKRSKEHTKLLSTHCEWISDWAIDYNIPGGADKEGWQYAIDFPANYHAHKKLTDCVRRRRWMKRCRLSSSGPWQELSQSKILDAALQVLDEDVDHSCSGERNTAVAAWAIASNGDVLIRHGVCSLNPRGDAWEHITSDQPLVGISVGPTGQVWTVARNGMVFFRYGISRQNPCGDAWQQVEAPAGVTFKAISVGRAGIWALDNQQRLAVRKEISRTFPEGSHWQFLPNAANVPPHTDQHCGFRSVSVGSEVWAISLNGIICRRCGITEENPAGVGWNLGIAGQWQNVSVEGYM", "length": 1350 }, "evidence": [ { "id": "A0A9J7FWV9", "url": "https://omabrowser.org/oma/group/A0A9J7FWV9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9" } ], "pmid": "" }, { "name": "regulation of autophagosome maturation", "id": "GO:1901096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-3-phosphate binding", "id": "GO:0032266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032266", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1150, "end_pos": 1152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1157, "end_pos": 1159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FWV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV9" }, { "id": "SM00693", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00693" }, { "id": "SM00694", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00694" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peroxin/Ferlin", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 125, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 363, 486 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1150, "end_pos": 1152 }, { "start_pos": 1157, "end_pos": 1159 }, { "start_pos": 444, "end_pos": 446 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": 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"site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FW69-1", "uniprot_ac": "A0A9J7FW69", "uniprot_id": "A0A9J7FW69_CRIGR", "mass": { "chemical_mass": 36645.0, "monoisotopic_mass": 36645.0 }, "refseq": { "ac": "XP_007653255", "name": "palmitoyltransferase ZDHHC7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653255" }, "gene_names": [ { "name": "Zdhhc7", "type": "recommended", "evidence": [ { "id": "A0A9J7FW69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ] }, { "name": "Zdhhc7", "type": "synonym", "evidence": [ { "id": "XP_007653255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653255" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7FW69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "A0A9J7FW69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69/entry#names_and_taxonomy" } ] }, { "name": "palmitoyltransferase ZDHHC7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007653255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653255" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613583.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007653255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653255" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zdhhc7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69", "locus": {} } ], "crossref": [ { "id": "100771824", "url": "https://www.ncbi.nlm.nih.gov/gene/100771824", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771824", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771824", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WYSMING", "url": "https://omabrowser.org/oma/group/WYSMING/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FRR0", "url": "https://www.orthodb.org/?gene=A0A9J7FRR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FW69", "url": "https://www.orthodb.org/?gene=A0A9J7FW69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3GRX0", "url": "https://www.orthodb.org/?gene=G3GRX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007653255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653255", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FRR0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW69-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3GRX0", "url": "https://www.uniprot.org/uniprotkb/G3GRX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3GRX0-1", "url": "https://www.uniprot.org/uniprotkb/G3GRX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPSGHRLRDIEHHPLLTDNDNYDSASSSSSEADMVDRVWFIRDGCGMVCAVMTWLLVIYADFVVTFVMLLPSKDFWYSVVNGVIFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCRKQGPEWCALLCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALSSVHALILCGLQFISCVRGQWTECSDFSPPITVILLVFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRFRRLQMRARKGSPEFSV", "length": 320, "header": "tr|A0A9J7FW69-1|A0A9J7FW69_CRIGR Isoform 1 of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc7 PE=3 SV=1 CANONICAL=A0A9J7FW69-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69/entry#A0A9J7FRR0-1", "sequence": { "sequence": "MLLPSKDFWYSVVNGVIFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCRKQGPEWCALLCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALSSVHALILCGLQFISCVRGQWTECSDFSPPITVILLVFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRFRRLQMRARKGSPEFSV", "length": 252, "header": "tr|A0A9J7FRR0-1|A0A9J7FW69_CRIGR Computationally mapped isoform of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc7 PE=3 SV=1 CANONICAL=A0A9J7FW69-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FW69-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69/entry#A0A9J7FW69-1", "sequence": { "sequence": "MQPSGHRLRDIEHHPLLTDNDNYDSASSSSSEADMVDRVWFIRDGCGMVCAVMTWLLVIYADFVVTFVMLLPSKDFWYSVVNGVIFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCRKQGPEWCALLCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALSSVHALILCGLQFISCVRGQWTECSDFSPPITVILLVFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRFRRLQMRARKGSPEFSV", "length": 320, "header": "tr|A0A9J7FW69-1|A0A9J7FW69_CRIGR Isoform 1 of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc7 PE=3 SV=1 CANONICAL=A0A9J7FW69-1" }, "locus": {} }, { "isoform_ac": "G3GRX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69/entry#G3GRX0-1", "sequence": { "sequence": "MQPSGHRLRDIEHHPLLTDNDNYDSASSSSSEADMVDRVWFIRDGCGMVCAVMTWLLVIYADFVVTFVMLLPSKDFWYSVVNGVIFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALSSVHALILCGLQFISCVRGQWTECSDFSPPITVILLVFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRFRRLQMRARKGSPEFSV", "length": 308, "header": "tr|G3GRX0-1|A0A9J7FW69_CRIGR Computationally mapped isoform of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc7 PE=3 SV=1 CANONICAL=A0A9J7FW69-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GRX0", "url": "https://www.uniprot.org/uniprotkb/G3GRX0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GRX0", "url": "https://www.uniprot.org/uniprotkb/G3GRX0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771824", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771824", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NVK1-1", "protein_name": "Palmitoyltransferase", "gene_name": "ZDHHC7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSSGHRFRDVEHHPLLAENDSYDSSSSEADMAERVWFIRDGCGMVCAIMTWLLVVYADFVVTFVMLLPSKDFWYSVINGVLFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMDNLQLKPGEVIYKCPKCCSIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALISAHALILCGFQFFSCVRGQWTECSDFSPPVTVILMIFLCLEGFLFLTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGQPSLLWINPFAGFRIRQILLRSKKGGPEFSV", "length": 305 }, "evidence": [ { "id": "A0A9J7FW69", "url": "https://omabrowser.org/oma/group/A0A9J7FW69/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A4X1T3L7-1", "protein_name": "Palmitoyltransferase", "gene_name": "ZDHHC7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPSPGHRLRDVEHHPLLSESDAYDSAPSSSSEADGADRVWFIRDGCGVVCAVLTWLLVVYADFVVTFVMLLPSKDFWYAVLNGVSFNCLAVLALSSHLRTMLTDPGAVPKGNATKEFMESLQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALASVHALVLCGLQFISCVRGQWTECSGFSPPVTVILLIFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRLRRLQTRPRKGGPEFSV", "length": 308 }, "evidence": [ { "id": "A0A9J7FW69", "url": "https://omabrowser.org/oma/group/A0A9J7FW69/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6DHI1-1", "protein_name": "Palmitoyltransferase ZDHHC7", "gene_name": "zdhhc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQSSGQRLRDVEQHQPLLSGGEEEVTAGRVWFIQDSCGMVCAFMTWSLVMYAEFVVNFVMLLPSKNFWYTLINGVAFNFLAVLALTSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCSIKPERAHHCSICKRCIRKMDHHCPWVNNCVGENNQRFFVLFTMYIASISLHALCLSGFHFFTCVKVQWNECSDFSPPVAVMLLIFLCLEALLFLTFTAVMFGTQIHSICNDETEIERLKNEKPTWERRVRWDGMKAVFGGPPSLLWFNPFAGLRLRMLMVRARRSGAEFSV", "length": 299 }, "evidence": [ { "id": "A0A9J7FW69", "url": "https://omabrowser.org/oma/group/A0A9J7FW69/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q91WU6-1", "protein_name": "Palmitoyltransferase ZDHHC7", "gene_name": "Zdhhc7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPSGHRLRDIEHHPLLTDNDNYDSASSSSSETDMADRVWFIRDGCGMVCAVMTWLLVVYADFVVTFVMLLPSKDFWYSVVNGVLFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALSSVHALILCGLQFISCVRGQWTECSDFSPPITVILLVFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRLRRLQMRTRKGGPEFSV", "length": 308 }, "evidence": [ { "id": "A0A9J7FW69", "url": "https://omabrowser.org/oma/group/A0A9J7FW69/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923G5-1", "protein_name": "Palmitoyltransferase ZDHHC7", "gene_name": "Zdhhc7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPSGHRLRDIEHHPLLTDNDNYDSASSSSSEADMADRVWFIRDGCGMVCAVMTWLLVVYADFVVTFVMLLPSKDFWYSVVNGVLFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALSSIHALILCGLQFISCVRGQWTECSDFSPPITVILLVFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRFRRLQMRTRKGGPEFSV", "length": 308 }, "evidence": [ { "id": "A0A9J7FW69", "url": "https://omabrowser.org/oma/group/A0A9J7FW69/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NXF8-1", "protein_name": "Palmitoyltransferase ZDHHC7", "gene_name": "ZDHHC7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPSGHRLRDVEHHPLLAENDNYDSSSSSSSEADVADRVWFIRDGCGMICAVMTWLLVAYADFVVTFVMLLPSKDFWYSVVNGVIFNCLAVLALSSHLRTMLTDPGAVPKGNATKEYMESLQLKPGEVIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMYIALSSVHALILCGFQFISCVRGQWTECSDFSPPITVILLIFLCLEGLLFFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSVFGGPPSLLWMNPFVGFRFRRLPTRPRKGGPEFSV", "length": 308 }, "evidence": [ { "id": "A0A9J7FW69", "url": "https://omabrowser.org/oma/group/A0A9J7FW69/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "androgen receptor signaling pathway", "id": "GO:0030521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030521", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "regulation of protein localization to plasma membrane", "id": "GO:1903076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903076", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "glucose import in response to insulin stimulus", "id": "GO:0044381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044381", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "regulation of Fas signaling pathway", "id": "GO:1902044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902044", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "polarized epithelial cell differentiation", "id": "GO:0030859", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030859", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "positive regulation of D-glucose transmembrane transport", "id": "GO:0010828", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010828", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "regulation of G protein-coupled receptor signaling pathway", "id": "GO:0008277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008277", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "progesterone receptor signaling pathway", "id": "GO:0050847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050847", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "negative regulation of catabolic process", "id": "GO:0009895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009895", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" }, { "name": "regulation of protein localization to cell-cell junction", "id": "GO:0150106", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150106", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019706", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "36683", "name": "", "equation": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7FW69-1", "A0A9J7K4V8-1", "A0A061IAW6-1", "G3IC21-1", "G3HT13-1", "G3HRH7-1", "A0A9J7JWN6-1", "A0A9J7FYH6-1", "A0A9J7F608-1", "A0A9J7JS16-1", "A0A9J7FKQ2-1", "A0A8C2M959-1", "A0A9J7FES5-1", "A0A9J7FGJ2-1", "A0A8C2M019-1", "A0A8C2N4B4-1", "A0A061HVX4-1", "A0A061IE10-1", "A0A3L7HQY8-1", "A0A8C2LCM5-1", "A0A9J7JJ84-1", "A0A9J7H2R9-1", "A0A9J7GKL6-1", "A0A9J7GX65-1", "A0A9J7H176-1", "A0A9J7KAZ1-1", "A0A9J7JED5-1", "P04773-1" ], "evidence": [ { "id": "36683", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/36683" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HVX4", "gene_name": "Zdhhc15", "activity": [ { "ec_number": "2.3.1.225", "activity": "L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA.", "evidence": [ { "id": "A0A061HVX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVX4" } ] }, { "ec_number": "2.3.1.225", "activity": "", "evidence": [ { "id": "A0A061HVX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVX4" } ] } ] }, { "uniprot_ac": "A0A061IAW6", 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"monoisotopic_mass": 52239.0 }, "refseq": { "ac": "XP_027272532", "name": "BAG family molecular chaperone regulator 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272532" }, "gene_names": [ { "name": "Bag5", "type": "recommended", "evidence": [ { "id": "A0A9J7G020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ] }, { "name": "Bag5", "type": "synonym", "evidence": [ { "id": "XP_027272532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272532" } ] } ], "protein_names": [ { "name": "BAG family molecular chaperone regulator 5", "type": "recommended", "evidence": [ { "id": "A0A9J7G020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020/entry#names_and_taxonomy" } ] }, { "name": "BAG family molecular chaperone regulator 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027272532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272532" } ] }, { "name": "Bcl-2-associated athanogene 5", "type": "synonym", "evidence": [ { "id": "A0A9J7G020", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272532" } ] }, { "annotation": "Co-chaperone for HSP/HSP70 proteins. It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding. Has an essential role in maintaining proteostasis at junctional membrane complexes (JMC), where it may function as a scaffold between the HSPA8 chaperone and JMC proteins enabling correct, HSPA8-dependent JMC protein folding. Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN.", "evidence": [ { "database": "UniProtKB", "id": "G3H379", "url": "https://www.uniprot.org/uniprotkb/G3H379#function" }, { "database": "UniProtKB", "id": "ARBA00057090", "url": "https://www.uniprot.org/uniprotkb/ARBA00057090#function" }, { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bag5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020", "locus": {} } ], "crossref": [ { "id": "A0A9J7G020", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G020", "database": "AlphaFoldDB", "categories": [] }, { "id": "100757492", "url": "https://www.ncbi.nlm.nih.gov/gene/100757492", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757492", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757492", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGNQHPA", "url": "https://omabrowser.org/oma/group/MGNQHPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G020", "url": "https://www.orthodb.org/?gene=A0A9J7G020", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12329:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12329:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G020-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H379", "url": "https://www.uniprot.org/uniprotkb/G3H379", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H379-1", "url": "https://www.uniprot.org/uniprotkb/G3H379-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTGSACETEHRSMDMGNQHPSISRLQEIQREVKSIEPQVVGFSGLADDKNYKRLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETEGLLKELEQNANHPHRIEIQNIFKEAQALVKEKIVPFYSGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCMKKQPSLPLSEDVHPSVAKINLVMCEVNKARGTLIALLMGVDSTETCRHLSCVLSGLMADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADSTHAFDLGQNHSILKIEKVLKRMREIKNELLQAQSPPELYLSSKTELQGLIGQLDEVSVEKNPCIREARRRAVIEVQTLITYLDLKEALEKRKLFPSEENPPHKAVWDVLGNLSEIQGEVLSFGGNRTDKNYIRLEELLTKQLLTLDAVDPQGEEKCKSARKQAVKLAQNILSYLDLKSDEWEY", "length": 460, "header": "tr|A0A9J7G020-1|A0A9J7G020_CRIGR Isoform 1 of BAG family molecular chaperone regulator 5 OS=Cricetulus griseus OX=10029 GN=Bag5 PE=4 SV=1 CANONICAL=A0A9J7G020-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G020-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020/entry#A0A9J7G020-1", "sequence": { "sequence": "MLTGSACETEHRSMDMGNQHPSISRLQEIQREVKSIEPQVVGFSGLADDKNYKRLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETEGLLKELEQNANHPHRIEIQNIFKEAQALVKEKIVPFYSGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCMKKQPSLPLSEDVHPSVAKINLVMCEVNKARGTLIALLMGVDSTETCRHLSCVLSGLMADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADSTHAFDLGQNHSILKIEKVLKRMREIKNELLQAQSPPELYLSSKTELQGLIGQLDEVSVEKNPCIREARRRAVIEVQTLITYLDLKEALEKRKLFPSEENPPHKAVWDVLGNLSEIQGEVLSFGGNRTDKNYIRLEELLTKQLLTLDAVDPQGEEKCKSARKQAVKLAQNILSYLDLKSDEWEY", "length": 460, "header": "tr|A0A9J7G020-1|A0A9J7G020_CRIGR Isoform 1 of BAG family molecular chaperone regulator 5 OS=Cricetulus griseus OX=10029 GN=Bag5 PE=4 SV=1 CANONICAL=A0A9J7G020-1" }, "locus": {} }, { "isoform_ac": "G3H379-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020/entry#G3H379-1", "sequence": { "sequence": "MDMGNQHPSISRLQEIQREVKSIEPQVVGFSGLADDKNYKRLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETEGLLKELEQNANHPHRIEIQNIFKEAQALVKEKIVPFYSGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCMKKQPSLPLSEDVHPSVAKINLVMCEVNKARGTLIALLMGVDSTETCRHLSCVLSGLMADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADSTHAFDLGQNHSILKIEKVLKRMREIKNELLQAQSPPELYLSSKTELQGLIGQLDEVSVEKNPCIREARRRAVIEVQTLITYLDLKEALEKRKLFPSEENPPHKAVWDVLGNLSEIQGEVLSFGGNRTDKNYIRLEELLTKQLLTLDAVDPQGEEKCKSARKQAVKLAQNILSYLDLKSDEWEY", "length": 447, "header": "tr|G3H379-1|A0A9J7G020_CRIGR Computationally mapped isoform of BAG family molecular chaperone regulator 5 OS=Cricetulus griseus OX=10029 GN=Bag5 PE=4 SV=1 CANONICAL=A0A9J7G020-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H379", "url": "https://www.uniprot.org/uniprotkb/G3H379" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H379", "url": "https://www.uniprot.org/uniprotkb/G3H379" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757492", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757492", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PX02-1", "protein_name": "BAG family molecular chaperone regulator 5", "gene_name": "BAG5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDMGNQHPSIKRLHEIQKEVKEIEQQVAVFSGLSTDRDYKKLERSLTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNANHPRRLEIEAIFKEAQALVEREITPFYQGGNCVNEEFEEGIQDVVLRLTQVKTGGKVSLRKARYRTLTKVCAVQEIIESCAKRQLSLPLSNDAHPSVSKINSVMCEVNKARGTLIALLMGVSSNDTCRHLACVLTGLVADLDALDVCGRTEIRNYRKEVVEEINKLQKYLDLDEEANSTHAYDLAQNQSILKIEEIRKKLKEVNSLLLKTENASDLYLGSKAELQGLIAQLDEVSPGKNPCIREARRRAVIEVQTLITYIDLKEALGKRQMYAEQTAAEHQSHKAVWTVLGNLSQIQQEVISFDGNRTDKNYMRLEELLTKQLLALDAVDPQGDERCKAARKQAVKLAQNILYYLDMKTDEWEY", "length": 450 }, "evidence": [ { "id": "A0A9J7G020", "url": "https://omabrowser.org/oma/group/A0A9J7G020/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q5QJC9-1", "protein_name": "BAG family molecular chaperone regulator 5", "gene_name": "Bag5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDMGNQHPSISRLQEIQREVKSIEQQVVGFSGLSDDKNYKRLERILTKQLFEIDSVDTEGKGDIQQARKRAAQDTERLLKELEQNANHPHRIEIKNIFQEAQALVKEKTVPFYSGSNCVTSEFEEAIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCVRKQPSLPLSEDVHPSVAKINSVMCEVNKARGTLIALLMGVDSSETCRHLSCVLSGLMADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADNTHAFDLGQNHSIIKIENVLKRMREMKNELLQAQSPPELYLRSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYLDLKEALEKRKLFPCEETPPHKAVWNVLGNLSEIQGEVLSFGGNRTDKNYIRLEELLTKQLLTLDAVDPLGEEKCKAARKQAVKLAQNILSYLDMKSDEWEY", "length": 447 }, "evidence": [ { "id": "A0A9J7G020", "url": "https://omabrowser.org/oma/group/A0A9J7G020/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CI32-1", "protein_name": "BAG family molecular chaperone regulator 5", "gene_name": "Bag5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDMGNQHPSISRLQEIQREVKAIEPQVVGFSGLSDDKNYKRLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNIFKEAQALVKDKIVPFYSGGNCVTDEFEEGIQDIILRLTHVKTGGKVSLRKARYRTLTKICAVQEVIEDCMKKQPSLPLSEDVHPSVAKINSVMCEVNKARGTLIALLMGVDSSETCRHLSCVLSGLIADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADSTHAFDLGQNHSIIKIENVLKRMREIKNELLQAQSPPELYLRAKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQILITYLDLKEALEKRKLFPCEEHPPHKAVWEILGNLSEILGEVLSFGGNRTDKNYIRLEELLTKQLLALDAVDPQGEEKCKAARKQAVKLAQNILSYLDMKSDEWEY", "length": 447 }, "evidence": [ { "id": "A0A9J7G020", "url": "https://omabrowser.org/oma/group/A0A9J7G020/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UL15-1", "protein_name": "BAG family molecular chaperone regulator 5", "gene_name": "BAG5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDMGNQHPSISRLQEIQKEVKSVEQQVIGFSGLSDDKNYKKLERILTKQLFEIDSVDTEGKGDIQQARKRAAQETERLLKELEQNANHPHRIEIQNIFEEAQSLVREKIVPFYNGGNCVTDEFEEGIQDIILRLTHVKTGGKISLRKARYHTLTKICAVQEIIEDCMKKQPSLPLSEDAHPSVAKINFVMCEVNKARGVLIALLMGVNNNETCRHLSCVLSGLIADLDALDVCGRTEIRNYRREVVEDINKLLKYLDLEEEADTTKAFDLRQNHSILKIEKVLKRMREIKNELLQAQNPSELYLSSKTELQGLIGQLDEVSLEKNPCIREARRRAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRTDKNYIRLEELLTKQLLALDAVDPQGEEKCKAARKQAVRLAQNILSYLDLKSDEWEY", "length": 447 }, "evidence": [ { "id": "A0A9J7G020", "url": "https://omabrowser.org/oma/group/A0A9J7G020/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "inclusion body", "id": "GO:0016234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016234", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "junctional membrane complex", "id": "GO:0030314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030314", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "adenyl-nucleotide exchange factor activity", "id": "GO:0000774", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000774", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "negative regulation of neuron projection development", "id": "GO:0010977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010977", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "negative regulation of protein ubiquitination", "id": "GO:0031397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway", "id": "GO:1902176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902176", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G020", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" } ], "pmid": "" }, { "name": "negative regulation of proteasomal ubiquitin-dependent protein 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G020" }, { "id": "PS51035", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51035" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAG", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 99, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 286, "end_pos": 288 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 402, "end_pos": 404 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"uniprot_canonical_ac": "A0A9J7FV24-1", "uniprot_ac": "A0A9J7FV24", "uniprot_id": "A0A9J7FV24_CRIGR", "mass": { "chemical_mass": 98610.0, "monoisotopic_mass": 98610.0 }, "refseq": { "ac": "XP_016829798", "name": "interleukin enhancer-binding factor 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829798" }, "gene_names": [ { "name": "Ilf3", "type": "recommended", "evidence": [ { "id": "A0A9J7FV24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24" } ] }, { "name": "Ilf3", "type": "synonym", "evidence": [ { "id": "XP_016829798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829798" } ] } ], "protein_names": [ { "name": "Interleukin enhancer-binding factor 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7FV24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#names_and_taxonomy" } ] }, { "name": "interleukin enhancer-binding factor 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016829798", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829798" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613752.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016829798", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829798" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ilf3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24", "locus": {} } ], "crossref": [ { "id": "cd19910", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19910", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19912", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19912", "database": "CDD", 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}, { "id": "PTHR45762:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45762:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07528", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07528", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20965", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20965", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016829798", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829798", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FS33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FS33-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FSV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUF6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV97", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV97-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JFN3", "url": 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"UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALYHHHFITRRRRFSHFQRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEGVKQQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSQFYSNGGHSGNAGGGGSGGGGGSSNYSSYYQGDSYNSPVPPKHAGKKPLHGGQQKSSYSSGYQSHQGQQQPYNQSQYSSYSTPQGKQKGYSHGQGSYSYSNSYNSPGGGGGSDYSYDSKFNYSGSGGRSGGNSYGSSGSSYNTGSHGGYGGGSGGSSSYQGKQGGYSSQSNYSSPGSSQSYSGPSSSYQSSQGGYSRNTEHSMNYQYR", "length": 918, "header": "tr|A0A9J7FV24-1|A0A9J7FV24_CRIGR Isoform 1 of Interleukin enhancer-binding factor 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FS33-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7FS33-1", "sequence": { "sequence": "MALYHHHFITRRRRFSHFQRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEGVKQQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSDFFTDCYGYHDFGAS", "length": 725, "header": "tr|A0A9J7FS33-1|A0A9J7FV24_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FSJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7FSJ2-1", "sequence": { "sequence": "MALYHHHFITRRRRFSHFQRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEGVKQQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSQFYSNGGHSGNAGGGGSGGGGGSSNYSSYYQGDSYNSPVPPKHAGKKPLHGGQQKSSYSSGYQSHQGQQQPYNQSQYSSYSTPQGKQKGYSHGQGSYSYSNSYNSPGGGGGSDYSYDSKFRGYSSQSNYSSPGSSQSYSGPSSSYQSSQGGYSRNTEHSMNYQYR", "length": 875, "header": "tr|A0A9J7FSJ2-1|A0A9J7FV24_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FSV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7FSV8-1", "sequence": { "sequence": "MFSHFQRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEGVKQQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSQFYSNGGHSGNAGGGGSGGGGGSSNYSSYYQGDSYNSPVPPKHAGKKPLHGGQQKSSYSSGYQSHQGQQQPYNQSQYSSYSTPQGKQKGYSHGQGSYSYSNSYNSPGGGGGSDYSYDSKFNYSGSGGRSGGNSYGSSGSSYNTGSHGGYGGGSGGSSSYQGKQGGYSSQSNYSSPGSSQSYSGPSSSYQSSQGGYSRNTEHSMNYQYR", "length": 905, "header": "tr|A0A9J7FSV8-1|A0A9J7FV24_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7FTA6-1", "sequence": { "sequence": "MALYHHHFITRRRRRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEGVKQQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSQFYSNGGHSGNAGGGGSGGGGGSSNYSSYYQGDSYNSPVPPKHAGKKPLHGGQQKSSYSSGYQSHQGQQQPYNQSQYSSYSTPQGKQKGYSHGQGSYSYSNSYNSPGGGGGSDYSYDSKFNYSGSGGRSGGNSYGSSGSSYNTGSHGGYGGGSGGSSSYQGKQGGYSSQSNYSSPGSSQSYSGPSSSYQSSQGGYSRNTEHSMNYQYR", "length": 913, "header": "tr|A0A9J7FTA6-1|A0A9J7FV24_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FUF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7FUF6-1", "sequence": { "sequence": "MALYHHHFITRRRRFSHFQRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEGVKQQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYRGYSSQSNYSSPGSSQSYSGPSSSYQSSQGGYSRNTEHSMNYQYR", "length": 754, "header": "tr|A0A9J7FUF6-1|A0A9J7FV24_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FV24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7FV24-1", "sequence": { "sequence": "MALYHHHFITRRRRFSHFQRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEGVKQQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSQFYSNGGHSGNAGGGGSGGGGGSSNYSSYYQGDSYNSPVPPKHAGKKPLHGGQQKSSYSSGYQSHQGQQQPYNQSQYSSYSTPQGKQKGYSHGQGSYSYSNSYNSPGGGGGSDYSYDSKFNYSGSGGRSGGNSYGSSGSSYNTGSHGGYGGGSGGSSSYQGKQGGYSSQSNYSSPGSSQSYSGPSSSYQSSQGGYSRNTEHSMNYQYR", "length": 918, "header": "tr|A0A9J7FV24-1|A0A9J7FV24_CRIGR Isoform 1 of Interleukin enhancer-binding factor 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FV97-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7FV97-1", "sequence": { "sequence": "MALYHHHFITRRRRFSHFQRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSQFYSNGGHSGNAGGGGSGGGGGSSNYSSYYQGDSYNSPVPPKHAGKKPLHGGQQKSSYSSGYQSHQGQQQPYNQSQYSSYSTPQGKQKGYSHGQGSYSYSNSYNSPGGGGGSDYSYDSKFNYSGSGGRSGGNSYGSSGSSYNTGSHGGYGGGSGGSSSYQGKQGGYSSQSNYSSPGSSQSYSGPSSSYQSSQGGYSRNTEHSMNYQYR", "length": 914, "header": "tr|A0A9J7FV97-1|A0A9J7FV97_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7FWG3-1", "sequence": { "sequence": "MALYHHHFITRRRRFSHFQRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSDFFTDCYGYHDFGAS", "length": 721, "header": "tr|A0A9J7FWG3-1|A0A9J7FWG3_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JFN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7JFN3-1", "sequence": { "sequence": "MRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEGVKQQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSQFYSNGGHSGNAGGGGSGGGGGSSNYSSYYQGDSYNSPVPPKHAGKKPLHGGQQKSSYSSGYQSHQGQQQPYNQSQYSSYSTPQGKQKGYSHGQGSYSYSNSYNSPGGGGGSDYSYDSKFNYSGSGGRSGGNSYGSSGSSYNTGSHGGYGGGSGGSSSYQGKQGGYSSQSNYSSPGSSQSYSGPSSSYQSSQGGYSRNTEHSMNYQYR", "length": 900, "header": "tr|A0A9J7JFN3-1|A0A9J7JFN3_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X6 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JM24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7JM24-1", "sequence": { "sequence": "MRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEGVKQQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSQFYSNGGHSGNAGGGGSGGGGGSSNYSSYYQGDSYNSPVPPKHAGKKPLHGGQQKSSYSSGYQSHQGQQQPYNQSQYSSYSTPQGKQKGYSHGQGSYSYSNSYNSPGGGGGSDYSYDSKFNYSGSGGRSGGNSYGSSGSSYNTGSHGGYGGGSGGSSSYQGKQGGYSSQSNYSSPGSSQSYSGPSSSYQSSQGGYSRNTEHSMNYQYR", "length": 897, "header": "tr|A0A9J7JM24-1|A0A9J7JM24_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X7 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#A0A9J7JNM0-1", "sequence": { "sequence": "MALYHHHFITRRRRRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSDFFTDCYGYHDFGAS", "length": 716, "header": "tr|A0A9J7JNM0-1|A0A9J7JNM0_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X12 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} }, { "isoform_ac": "G3H6B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV24/entry#G3H6B5-1", "sequence": { "sequence": "MALYHHHFITRRRRRPMRIFVNDDRHVMAKHSSVYPTQEELEAVQNMVSHTERALKAVSDWIDEQEKGSSELAEAENMDTPPDDESKEGAGEQKAEHMTRTLRGVMRVGLVAKGLLLKGDLDLELVLLCKEKPTTTLLDKVADNLAIQLTTVTEDKYEILQSVDDAAIVIKNTKEPPLSLTIHLTSPVVREEMEKVLAGETLSVNDPPDVLDRQKCLAALASLRHAKWFQARANGLKSCVIVIRVLRDLCTRVPSWGPLRGWPLELLCEKSIGTANRPMGAGEALRRVLECLASGIVMPDGSGIYDPCEKEATDAIGHLDRQQREDITQSAQHALRLAAFGQLHKVLGMDPLPSKMPKKPKNENPVDYTVQIPPSTTYAITPMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLISQTGPVHAPIFTMAVEVDGSTFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEESDGKPAVVAPPPVVEAVSNPSSVFPSDATTEQGPILTKHGKNPVMELNEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDAPLALEANKKKRAPVPVRGGPKFAAKPHNPGFGMGGPMHNEVPPPPNLRGRGRGGNIRGRGRGRGFGGTNHGGGYMNAGAGYGSYGYGSNSATAGYSQFYSNGGHSGNAGGGGSGGGGGSSNYSSYYQGDSYNSPVPPKHAGKKPLHGGQQKSSYSSGYQSHQGQQQPYNQSQYSSYSTPQGKQKGYSHGQGSYSYSNSYNSPGGGGGSDYSYDSKFNYSGSGGRSGGNSYGSSGSSYNTGSHGGYGGGSGGSSSYQGKQGGYSSQSNYSSPGSSQSYSGPSSSYQSSQGGYSRNTEHSMNYQYR", "length": 909, "header": "tr|G3H6B5-1|A0A9J7FV24_CRIGR Computationally mapped isoform of Interleukin enhancer-binding factor 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ilf3 PE=4 SV=1 CANONICAL=A0A9J7FV24-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273508", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273508" } ] }, { "annotation": "Immune regulatory cytokine.", "evidence": [ { "database": "UniProtKB", "id": "G3HB01", "url": "https://www.uniprot.org/uniprotkb/G3HB01#function" }, { "database": "UniProtKB", "id": "RU368043", "url": "https://www.uniprot.org/uniprotkb/RU368043#function" }, { "database": "UniProtKB", "id": "A0A9J7G1C0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1C0#function" }, { "database": "UniProtKB", "id": "A0A9J7G3A0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3A0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Il10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A0", "locus": {} } ], "crossref": [ { "id": "A0A9J7G3A0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G3A0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100759320", "url": "https://www.ncbi.nlm.nih.gov/gene/100759320", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759320", "url": 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"https://www.ncbi.nlm.nih.gov/protein/XP_003505969" }, "gene_names": [ { "name": "Xylb", "type": "recommended", "evidence": [ { "id": "A0A9J7FYD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2" } ] }, { "name": "Xylb", "type": "synonym", "evidence": [ { "id": "XP_003505969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505969" } ] } ], "protein_names": [ { "name": "Xylulose kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7FYD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2/entry#names_and_taxonomy" } ] }, { "name": "2.7.1.17", "type": "synonym", "evidence": [ { "id": "A0A9J7FYD2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2/entry#names_and_taxonomy" } ] }, { "name": "xylulose kinase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003505969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505969" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614199.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505969" } ] }, { "annotation": "Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.", "evidence": [ { "database": "UniProtKB", "id": "G3HQV5", "url": "https://www.uniprot.org/uniprotkb/G3HQV5#function" }, { "database": "UniProtKB", "id": "ARBA00003260", "url": "https://www.uniprot.org/uniprotkb/ARBA00003260#function" }, { "database": "UniProtKB", "id": "RU367058", "url": "https://www.uniprot.org/uniprotkb/RU367058#function" }, { "database": "UniProtKB", "id": "A0A9J7FY49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY49#function" }, { "database": "UniProtKB", "id": "A0A9J7FYA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA3#function" }, { "database": "UniProtKB", "id": "A0A9J7FYD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2#function" }, { "database": "UniProtKB", "id": "A0A9J7G2L2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2L2#function" }, { "database": "UniProtKB", "id": "A0A9J7JHY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHY8#function" }, { "database": "UniProtKB", "id": "A0A9J7GXN0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXN0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Xylb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYD2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYD2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07776", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07776", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750577", "url": "https://www.ncbi.nlm.nih.gov/gene/100750577", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750577", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750577", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FY49", "url": "https://www.orthodb.org/?gene=A0A9J7FY49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FYA3", "url": "https://www.orthodb.org/?gene=A0A9J7FYA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FYD2", "url": "https://www.orthodb.org/?gene=A0A9J7FYD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G2L2", "url": "https://www.orthodb.org/?gene=A0A9J7G2L2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10196:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10196:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003505969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505969", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10964", "url": "https://www.rhea-db.org/rhea/10964", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FY49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY49-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2L2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2L2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXN0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HQV5", "url": "https://www.uniprot.org/uniprotkb/G3HQV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HQV5-1", "url": "https://www.uniprot.org/uniprotkb/G3HQV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAERAGRRCCLGWDFSTQQVKIVAVDAELNVFYEDSVHFDTDLPEFGTQGGVHVHKDRLTVTSPVLMWVQALDLILEKMKASGFDFSQVLALSGAGQQHGSVYWKTGASLVLSSLSPALPLCQQLQACFSISDCPIWMDSSTTAQCRQLEAAVGGARALSCLTGSRAYERFTGNQIAKLFQQNPEAYSNSERISLVSSFAASLFLGGYSPIDYSDGSGMNLLQIQEKVWSQACLGACAPDLEEKLGSPVPSCSVVGAISSYYVQRYGFLPTCQVVAFTGDNPASLAGMRLEEGDFAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDVQYYMALLCFKNGSLIREKIRDESASGSWNKFSKALQSTEMGNNGNLGFYFDVMEITPEIIGRHRFNAENIEVSAFPGDVEIRALIEGQFMAKRIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVMDTSSSACVGSAYRAFHGLAGGAGVAFSEVAKSAPRPSLAATPSPGASQVYEALLPRYAELEQRILSQARRPLE", "length": 536, "header": "tr|A0A9J7FYD2-1|A0A9J7FYD2_CRIGR Isoform 1 of Xylulose kinase OS=Cricetulus griseus OX=10029 GN=Xylb PE=3 SV=1 CANONICAL=A0A9J7FYD2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FY49-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2/entry#A0A9J7FY49-1", "sequence": { "sequence": "MAERAGRRCCLGWDFSTQQVKIVAVDAELNVFYEDSVHFDTDLPEFGTQGGVHVHKDRLTVTSPVLMWVQALDLILEKMKASGFDFSQVLALSGAGQQHGSVYWKTGASLVLSSLSPALPLCQQLQACFSISDCPIWMDSSTTAQCRQLEAAVGGARALSCLTGSRAYERFTGNQIAKLFQQNPEAYSNSERISLVSSFAASLFLGGYSPIDYSDGSGMNLLQIQEKVWSQACLGACAPDLEEKLGSPVPSCSVVGAISSYYVQRYGFLPTCQVVAFTGDNPASLAGMRLEEGDFAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDVQYYMALLCFKNGSLIREKIRDESASGSWNKFSKALQSTEMGNNGNLVPKTKILATGGASHNKDILQVLADVFGAPVYVMDTSSSACVGSAYRAFHGLAGGAGVAFSEVAKSAPRPSLAATPSPGASQVYEALLPRYAELEQRILSQARRPLE", "length": 479, "header": "tr|A0A9J7FY49-1|A0A9J7FY49_CRIGR Computationally mapped isoform of Xylulose kinase OS=Cricetulus griseus OX=10029 GN=Xylb PE=3 SV=1 CANONICAL=A0A9J7FYD2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2/entry#A0A9J7FYA3-1", "sequence": { "sequence": "MFSRDHPTPGFLACFSISDCPIWMDSSTTAQCRQLEAAVGGARALSCLTGSRAYERFTGNQIAKLFQQNPEAYSNSERISLVSSFAASLFLGGYSPIDYSDGSGMNLLQIQEKVWSQACLGACAPDLEEKLGSPVPSCSVVGAISSYYVQRYGFLPTCQVVAFTGDNPASLAGMRLEEGDFAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDVQYYMALLCFKNGSLIREKIRDESASGSWNKFSKALQSTEMGNNGNLGFYFDVMEITPEIIGRHRFNAENIEVSAFPGDVEIRALIEGQFMAKRIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVMDTSSSACVGSAYRAFHGLAGGAGVAFSEVAKSAPRPSLAATPSPGASQVYEALLPRYAELEQRILSQARRPLE", "length": 422, "header": "tr|A0A9J7FYA3-1|A0A9J7FYA3_CRIGR Computationally mapped isoform of Xylulose kinase OS=Cricetulus griseus OX=10029 GN=Xylb PE=3 SV=1 CANONICAL=A0A9J7FYD2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2/entry#A0A9J7FYD2-1", "sequence": { "sequence": "MAERAGRRCCLGWDFSTQQVKIVAVDAELNVFYEDSVHFDTDLPEFGTQGGVHVHKDRLTVTSPVLMWVQALDLILEKMKASGFDFSQVLALSGAGQQHGSVYWKTGASLVLSSLSPALPLCQQLQACFSISDCPIWMDSSTTAQCRQLEAAVGGARALSCLTGSRAYERFTGNQIAKLFQQNPEAYSNSERISLVSSFAASLFLGGYSPIDYSDGSGMNLLQIQEKVWSQACLGACAPDLEEKLGSPVPSCSVVGAISSYYVQRYGFLPTCQVVAFTGDNPASLAGMRLEEGDFAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDVQYYMALLCFKNGSLIREKIRDESASGSWNKFSKALQSTEMGNNGNLGFYFDVMEITPEIIGRHRFNAENIEVSAFPGDVEIRALIEGQFMAKRIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVMDTSSSACVGSAYRAFHGLAGGAGVAFSEVAKSAPRPSLAATPSPGASQVYEALLPRYAELEQRILSQARRPLE", "length": 536, "header": "tr|A0A9J7FYD2-1|A0A9J7FYD2_CRIGR Isoform 1 of Xylulose kinase OS=Cricetulus griseus OX=10029 GN=Xylb PE=3 SV=1 CANONICAL=A0A9J7FYD2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2/entry#A0A9J7G2L2-1", "sequence": { "sequence": "MAERAGRRCCLGWDFSTQQVKIVAVDAELNVFYEDSVHFDTDLPEFGTQGGVHVHKDRLTVTSPVLMWVQQHGSVYWKTGASLVLSSLSPALPLCQQLQACFSISDCPIWMDSSTTAQCRQLEAAVGGARALSCLTGSRAYERFTGNQIAKLFQQNPEAYSNSERISLVSSFAASLFLGGYSPIDYSDGSGMNLLQIQEKVWSQACLGACAPDLEEKLGSPVPSCSVVGAISSYYVQRYGFLPTCQVVAFTGDNPASLAGMRLEEGDFAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDVQYYMALLCFKNGSLIREKIRDESASGSWNKFSKALQSTEMGNNGNLGFYFDVMEITPEIIGRHRFNAENIEVSAFPGDVEIRALIEGQFMAKRIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVMDTSSSACVGSAYRAFHGLAGGAGVAFSEVAKSAPRPSLAATPSPGASQVYEALLPRYAELEQRILSQARRPLE", "length": 509, "header": "tr|A0A9J7G2L2-1|A0A9J7G2L2_CRIGR Computationally mapped isoform of Xylulose kinase OS=Cricetulus griseus OX=10029 GN=Xylb PE=3 SV=1 CANONICAL=A0A9J7FYD2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2/entry#A0A9J7GXN0-1", "sequence": { "sequence": "MDSSTTAQCRQLEAAVGGARALSCLTGSRAYERFTGNQIAKLFQQNPEAYSNSERISLVSSFAASLFLGGYSPIDYSDGSGMNLLQIQEKVWSQACLGACAPDLEEKLGSPVPSCSVVGAISSYYVQRYGFLPTCQVVAFTGDNPASLAGMRLEEGDFAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDVQYYMALLCFKNGSLIREKIRDESASGSWNKFSKALQSTEMGNNGNLGFYFDVMEITPEIIGRHRFNAENIEVSAFPGDVEIRALIEGQFMAKRIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVMDTSSSACVGSAYRAFHGLAGGAGVAFSEVAKSAPRPSLAATPSPGASQVYEALLPRYAELEQRILSQARRPLE", "length": 399, "header": "tr|A0A9J7GXN0-1|A0A9J7GXN0_CRIGR Computationally mapped isoform of Xylulose kinase OS=Cricetulus griseus OX=10029 GN=Xylb PE=3 SV=1 CANONICAL=A0A9J7FYD2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2/entry#A0A9J7JHY8-1", "sequence": { "sequence": "MNLLQIQEKVWSQACLGACAPDLEEKLGSPVPSCSVVGAISSYYVQRYGFLPTCQVVAFTGDNPASLAGMRLEEGDFAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDVQYYMALLCFKNGSLIREKIRDESASGSWNKFSKALQSTEMGNNGNLGFYFDVMEITPEIIGRHRFNAENIEVSAFPGDVEIRALIEGQFMAKRIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVMDTSSSACVGSAYRAFHGLAGGAGVAFSEVAKSAPRPSLAATPSPGASQVYEALLPRYAELEQRILSQARRPLE", "length": 318, "header": "tr|A0A9J7JHY8-1|A0A9J7JHY8_CRIGR Computationally mapped isoform of Xylulose kinase OS=Cricetulus griseus OX=10029 GN=Xylb PE=3 SV=1 CANONICAL=A0A9J7FYD2-1" }, "locus": {} }, { "isoform_ac": "G3HQV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYD2/entry#G3HQV5-1", "sequence": { "sequence": "MKASGFDFSQVLALSGAGQQHGSVYWKTGASLVLSSLSPALPLCQQLQACFSISDCPIWMDSSTTAQCRQLEAAVGGARALSCLTGSRAYERFTGNQIAKLFQQNPEAYSNSERISLVSSFAASLFLGGYSPIDYSDGSGMNLLQIQEKVWSQACLGACAPDLEEKLGSPVPSCSVVGAISSYYVQRYGFLPTCQVVAFTGDNPASLAGMRLEEGDFAVSLGTSDTLFLWLQEPMPALEGHIFCNPVDVQYYMALLCFKNGSLIREKIRDESASGSWNKFSKALQSTEMGNNGNLGFYFDVMEITPEIIGRHRFNAENIEVSAFPGDVEIRALIEGQFMAKRIHAEGLGYRVMPKTKILATGGASHNKDILQVLADVFGAPVYVMDTSSSACVGSAYRAFHGLAGGAGVAFSEVAKSAPRPSLAATPSPGASQVYEALLPRYAELEQRILSQARRPLE", "length": 458, "header": "tr|G3HQV5-1|A0A9J7FYD2_CRIGR Computationally mapped isoform of Xylulose kinase OS=Cricetulus griseus OX=10029 GN=Xylb PE=3 SV=1 CANONICAL=A0A9J7FYD2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 504, "start_aa": "Thr", "end_pos": 504, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr504", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HQV5", "url": "https://www.uniprot.org/uniprotkb/G3HQV5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HU78", "url": "https://www.uniprot.org/uniprotkb/G3HU78" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764676", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764676", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LVY3-1", "protein_name": "ubiquitinyl hydrolase 1", "gene_name": "Otub2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HSASETSFNLISEKCDILSILRDHPENRIYQRKIQELSKRFTSIRKTKGDGNCFYRALGYSYLESLLGKGREILKFKERVLQTPNDLLAAGFEEHKFRNFFNAFYSVVELVEKDSSVSSLLKVFNDQSSSDRIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMAMECDHVQITALSQALNIALQVEYVDEMDTALNHHVFPEAATPSVYLLYKTSHYNILYAAEKH", "length": 236 }, "evidence": [ { "id": "A0A9J7G354", "url": 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"MSETPFNLISEKCDILSILRDHPENRIYQRKIQELSKRFTAIRKTKGDGNCFYRALGYSYLESLLGKSREILKFKERVLQTPNDLLAAGFEEHKFQNFFNAFYSVVELVEKDGSVSSLLKVFNDQSSSDRIVQFLRLLTSAFIRNRADFFRHFIDEEMDIRDFCTHEVEPMAMECDHIQITALSQALNIALQVEYVDEMDTALNHHVFPEAAIPSVYLLYKTSHYNILYAADKR", "length": 234 }, "evidence": [ { "id": "A0A9J7G354", "url": "https://omabrowser.org/oma/group/A0A9J7G354/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q96DC9-1", "protein_name": "Ubiquitin thioesterase OTUB2", "gene_name": "OTUB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSETSFNLISEKCDILSILRDHPENRIYRRKIEELSKRFTAIRKTKGDGNCFYRALGYSYLESLLGKSREIFKFKERVLQTPNDLLAAGFEEHKFRNFFNAFYSVVELVEKDGSVSSLLKVFNDQSASDHIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMATECDHIQITALSQALSIALQVEYVDEMDTALNHHVFPEAATPSVYLLYKTSHYNILYAADKH", "length": 234 }, "evidence": [ { "id": "A0A9J7G354", "url": "https://omabrowser.org/oma/group/A0A9J7G354/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQX0-1", "protein_name": "Ubiquitin thioesterase OTUB2", "gene_name": "Otub2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSETSFNLISEKCDILSILRDHPENRIYQRKIQELSKRFTSIRKTKGDGNCFYRALGYSYLESLLGKSREILKFKERVLQTPNDLLAAGFEEHKFRNFFNAFYSVVELVEKDSSVSSLLKVFNDQSSSDRIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMAMECDHVQITALSQALNIALQVEYVDEMDTALNHHVFPEAAIPSVYLLYKTSHYNILYAAEKH", "length": 234 }, "evidence": [ { "id": "A0A9J7G354", "url": "https://omabrowser.org/oma/group/A0A9J7G354/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of double-strand break repair", "id": "GO:2000780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000780", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G354", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G354" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G354", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G354" } ], "pmid": "" }, { "name": "protein K63-linked deubiquitination", "id": "GO:0070536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070536", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G354", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G354" } ], "pmid": "" }, { "name": "protein K48-linked deubiquitination", "id": "GO:0071108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071108", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G354", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G354" } ], "pmid": "" }, { "name": "protein K11-linked deubiquitination", "id": "GO:0035871", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035871", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G354", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G354" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G354", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G354" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G354", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G354" } ], "pmid": "" }, { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G354", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G354" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G354", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G354" }, { "id": "PS50802", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50802" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OTU", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 262, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 244 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"A0A9J7G0Y5", "uniprot_id": "A0A9J7G0Y5_CRIGR", "mass": { "chemical_mass": 95067.0, "monoisotopic_mass": 95067.0 }, "refseq": { "ac": "XP_003508836", "name": "cullin-5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508836" }, "gene_names": [ { "name": "Cul5", "type": "recommended", "evidence": [ { "id": "A0A9J7G0Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y5" } ] }, { "name": "Cul5", "type": "synonym", "evidence": [ { "id": "XP_003508836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508836" } ] } ], "protein_names": [ { "name": "Cullin-5", "type": "recommended", "evidence": [ { "id": "A0A9J7G0Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y5/entry#names_and_taxonomy" } ] }, { "name": "cullin-5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003508836", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508836" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614584.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508836" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cul5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y5", "locus": {} } ], "crossref": [ { "id": "A0A9J7G0Y5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G0Y5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100770463", "url": "https://www.ncbi.nlm.nih.gov/gene/100770463", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770463", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770463", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0Y5", "url": "https://www.orthodb.org/?gene=A0A9J7G0Y5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3I0C6", "url": "https://www.orthodb.org/?gene=G3I0C6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G0Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZX8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I0C6", "url": "https://www.uniprot.org/uniprotkb/G3I0C6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I0C6-1", "url": "https://www.uniprot.org/uniprotkb/G3I0C6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATSNLLKENEGIQLRKLKTTGQMRHLREKDKSSRENVPRKRNKGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGSSKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEVTLLGKQSSNKKSNMEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNSEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDEADINTFIYMA", "length": 814, "header": "tr|A0A9J7G0Y5-1|A0A9J7G0Y5_CRIGR Isoform 1 of Cullin-5 OS=Cricetulus griseus OX=10029 GN=Cul5 PE=3 SV=1 CANONICAL=A0A9J7G0Y5-1" }, "isoforms": [ { 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"tr|A0A9J7G0Y5-1|A0A9J7G0Y5_CRIGR Isoform 1 of Cullin-5 OS=Cricetulus griseus OX=10029 GN=Cul5 PE=3 SV=1 CANONICAL=A0A9J7G0Y5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y5/entry#A0A9J7GZX8-1", "sequence": { "sequence": 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"id": "XP_027274955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274955" } ] }, { "name": "NADH-ubiquinone oxidoreductase MNLL subunit", "type": "synonym", "evidence": [ { "id": "A0A9J7G2U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2U0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274955" } ] }, { "annotation": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. 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This record is derived from a genomic sequence (NW_003613630.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007650369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650369" } ] }, { "annotation": "IF-3 binds to the 28S ribosomal subunit and shifts the equilibrium between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.", "evidence": [ { "database": "UniProtKB", "id": "G3GWI6", "url": "https://www.uniprot.org/uniprotkb/G3GWI6#function" }, { "database": "UniProtKB", "id": "ARBA00059316", "url": "https://www.uniprot.org/uniprotkb/ARBA00059316#function" }, { "database": "UniProtKB", "id": "A0A9J7FZ76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ76#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ76" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mtif3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ76", "locus": {} } ], "crossref": [ { "id": "A0A9J7FZ76", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FZ76", "database": "AlphaFoldDB", "categories": [] }, { "id": "100763635", "url": "https://www.ncbi.nlm.nih.gov/gene/100763635", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036788", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036788", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763635", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763635", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SAGCVRW", "url": "https://omabrowser.org/oma/group/SAGCVRW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FZ76", "url": "https://www.orthodb.org/?gene=A0A9J7FZ76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3GWI6", "url": "https://www.orthodb.org/?gene=G3GWI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10938", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10938", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10938:SF0", "url": 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"MKKPKTVWTIKMLQFIFCHSLGYELRMAVLLKRLTLQTSIGTCFSKHIVKPDPAQLSLTASTPKLLYLILAKGFSTDGNTPGEKKQKRKDAFTNTGRKISERIIRVLDEKGTDLGMMHRADVIRLMDKLDLRLVQRNASSEPPEYQLMTGEQIHQERLRIREQEKTNPKTGPAATKELIFSSNIGQHDLDTKSKQIHQWIEKKYLVQVTIKKAKNAEQPRNEMDEIFNQILQTMTAIATFSSRPKAIRGGTASMCVFRPLSKKEMKAYRHTQETEGTDTLNKDDRNKESDVLCQGL", "length": 296, "header": "tr|A0A9J7FZ76-1|A0A9J7FZ76_CRIGR Isoform 1 of Translation initiation factor IF-3, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mtif3 PE=3 SV=1 CANONICAL=A0A9J7FZ76-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZ76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ76/entry#A0A9J7FZ76-1", "sequence": { "sequence": "MKKPKTVWTIKMLQFIFCHSLGYELRMAVLLKRLTLQTSIGTCFSKHIVKPDPAQLSLTASTPKLLYLILAKGFSTDGNTPGEKKQKRKDAFTNTGRKISERIIRVLDEKGTDLGMMHRADVIRLMDKLDLRLVQRNASSEPPEYQLMTGEQIHQERLRIREQEKTNPKTGPAATKELIFSSNIGQHDLDTKSKQIHQWIEKKYLVQVTIKKAKNAEQPRNEMDEIFNQILQTMTAIATFSSRPKAIRGGTASMCVFRPLSKKEMKAYRHTQETEGTDTLNKDDRNKESDVLCQGL", "length": 296, "header": "tr|A0A9J7FZ76-1|A0A9J7FZ76_CRIGR Isoform 1 of Translation initiation factor IF-3, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mtif3 PE=3 SV=1 CANONICAL=A0A9J7FZ76-1" }, "locus": {} }, { "isoform_ac": "G3GWI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ76/entry#G3GWI6-1", "sequence": { "sequence": "MAVLLKRLTLQTSIGTCFSKHIVKPDPAQLSLTASTPKLLYLILAKGFSTDGNTPGEKKQKRKDAFTNTGRKISERIIRVLDEKGTDLGMMHRADVIRLMDKLDLRLVQRNASSEPPEYQLMTGEQIHQERLRIREQEKTNPKTGPAATKELIFSSNIGQHDLDTKSKQIHQWIEKKYLVQVTIKKAKNAEQPRNEMDEIFNQILQTMTAIATFSSRPKAIRGGTASMCVFRPLSKKEMKAYRHTQETEGTDTLNKDDRNKESDVLCQGL", "length": 270, "header": "tr|G3GWI6-1|A0A9J7FZ76_CRIGR Computationally mapped isoform of Translation initiation factor IF-3, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mtif3 PE=3 SV=1 CANONICAL=A0A9J7FZ76-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GWI6", "url": "https://www.uniprot.org/uniprotkb/G3GWI6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GWI6", "url": "https://www.uniprot.org/uniprotkb/G3GWI6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763635", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763635", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZWK9-1", "protein_name": "Translation initiation factor IF-3, mitochondrial", "gene_name": "Mtif3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVLLKRLMPQAMKTDSSLLRRCFRRHTVKPDLARPSLTASTPKLLHLISAKGFSTVGDTEGERRQKRRDAFSNTGRKISERVIRVLDEKGVDLGTMHRADVIRLMDKQDLRLVQRNTTSEPPEYQLMTGAQIHQERLRIREQEKAKPKTGPTVTKELIFSSNIGQHDLDTKSKQIQQWIEKKYHVQVTIKKRKDAEQPGSEMDEIFNQILQTMPGIATFLSRPKAVRGGTASMCVFRHVSKKEEKAYRESQESQKGDTLSKDDRSSNKSDVLCQ", "length": 275 }, "evidence": 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"sequence": { "sequence": "MAALFLKKLTLQTVKTENYCIRRCLGKYILQGPAPTQQPPRPSCLIHAKAFSTEDTQDEMTKKKKNETAFSSVGRKINERIIHVLDEQGNDLGHMHRANVIRLMAERDLRLVKRDASAEPPQYQLLTGAQIHQERLRLREAERAAPKPGPTLTKELTFSSNIGQHDLDTKSKQIQQWIEKKYKVQITVKKGKSADEPEDKMEEMCNRIVQTMSGIATFSSRPQPIRGGKAVMCVLRPLSKKEEAAWKAAPDTPRRDALNGGDGKDGASGVLPQ", "length": 273 }, "evidence": [ { "id": "A0A9J7FZ76", "url": "https://omabrowser.org/oma/group/A0A9J7FZ76/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9CZD5-1", "protein_name": "Translation initiation factor IF-3, mitochondrial", "gene_name": "Mtif3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVLLMRLMLQTTKLDHNLIGRCLQRHAVKPDPAQLSLSASTPKLLYLTSAKGFSTAGDPQGERKQKRRDAFSNTGRKISERIIRVLDEKGMDLGMMHRADVIRLMNKQDLRLVQRNTSSEPPEYQLMTGEQIHQERLKLREQEKAKPKTGPTMTKELVFSSNIGQHDLDTKSKQIQQWIEKKYHVQVTIKRRKDAEQSEEETEEIFNQILQTMPDIATFSSRPKAIRGGTASMCVFRHLSKKEEKAYRESQESQRRDTLSKDDDGNSKESDVVCQ", "length": 276 }, "evidence": [ { "id": "A0A9J7FZ76", "url": "https://omabrowser.org/oma/group/A0A9J7FZ76/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2K0-1", "protein_name": "Translation initiation factor IF-3, mitochondrial", "gene_name": "MTIF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAALFLKRLTLQTVKSENSCIRCFGKHILQKTAPAQLSPIASAPRLSFLIHAKAFSTAEDTQNEGKKTKKNKTAFSNVGRKISQRVIHLFDEKGNDLGNMHRANVIRLMDERDLRLVQRNTSTEPAEYQLMTGLQILQERQRLREMEKANPKTGPTLRKELILSSNIGQHDLDTKTKQIQQWIKKKHLVQITIKKGKNVDVSENEMEEIFHQILQTMPGIATFSSRPQAVQGGKALMCVLRAFSKNEEKAYKETQETQERDTLNKDHGNDKESNVLHQ", "length": 278 }, "evidence": [ { "id": "A0A9J7FZ76", "url": "https://omabrowser.org/oma/group/A0A9J7FZ76/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ribosome disassembly", "id": "GO:0032790", "url": 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"https://www.uniprot.org/uniprotkb/A0A9J7FZ76" } ], "pmid": "" }, { "name": "translation factor activity, RNA binding", "id": "GO:0008135", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008135", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ76" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ76" } ], "pmid": "" }, { "name": "ribosome binding", "id": "GO:0043022", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043022", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": 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"end_pos": 139 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G145-1", "uniprot_ac": "A0A9J7G145", "uniprot_id": "A0A9J7G145_CRIGR", "mass": { "chemical_mass": 30978.0, "monoisotopic_mass": 30978.0 }, "refseq": { "ac": "XP_027274212", "name": "serine/arginine-rich splicing factor 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274212" }, "gene_names": [ { "name": "Srsf5", "type": "recommended", "evidence": [ { "id": "A0A9J7G145", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145" } ] }, { "name": "Srsf5", "type": "synonym", "evidence": [ { "id": "XP_027274212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274212" } ] } ], "protein_names": [ { "name": "Serine/arginine-rich splicing factor 5", "type": "recommended", "evidence": [ { "id": "A0A9J7G145", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145/entry#names_and_taxonomy" } ] }, { "name": "Delayed-early protein HRS", "type": "synonym", "evidence": [ { "id": "A0A9J7G145", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145/entry#names_and_taxonomy" } ] }, { "name": "Pre-mRNA-splicing factor SRP40", "type": "synonym", "evidence": [ { "id": "A0A9J7G145", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145/entry#names_and_taxonomy" } ] }, { "name": "Splicing factor, arginine/serine-rich 5", "type": "synonym", "evidence": [ { "id": "A0A9J7G145", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145/entry#names_and_taxonomy" } ] }, { "name": "serine/arginine-rich splicing factor 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027274212", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274212" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274212", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274212" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G145", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Srsf5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145", "locus": {} } ], "crossref": [ { "id": "A0A9J7G145", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G145", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12595", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12595", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757287", "url": "https://www.ncbi.nlm.nih.gov/gene/100757287", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757287", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757287", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRPKVNE", "url": "https://omabrowser.org/oma/group/HRPKVNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G145", "url": "https://www.orthodb.org/?gene=A0A9J7G145", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027274212", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274212", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G145", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G145-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H1N7", "url": "https://www.uniprot.org/uniprotkb/G3H1N7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H1N7-1", "url": "https://www.uniprot.org/uniprotkb/G3H1N7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRRSKSYSRSRSRSRSRSKSRSGSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN", "length": 270, "header": "tr|A0A9J7G145-1|A0A9J7G145_CRIGR Isoform 1 of Serine/arginine-rich splicing factor 5 OS=Cricetulus griseus OX=10029 GN=Srsf5 PE=3 SV=1 CANONICAL=A0A9J7G145-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G145-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145/entry#A0A9J7G145-1", "sequence": { "sequence": "MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRRSKSYSRSRSRSRSRSKSRSGSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN", "length": 270, "header": "tr|A0A9J7G145-1|A0A9J7G145_CRIGR Isoform 1 of Serine/arginine-rich splicing factor 5 OS=Cricetulus griseus OX=10029 GN=Srsf5 PE=3 SV=1 CANONICAL=A0A9J7G145-1" }, "locus": {} }, { "isoform_ac": "G3H1N7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145/entry#G3H1N7-1", "sequence": { "sequence": "MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHRSRSRSRSRTRSSSRSRSRSRSRRSKSYSRSRSRSRSRSKSRSGSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN", "length": 269, "header": "tr|G3H1N7-1|A0A9J7G145_CRIGR Computationally mapped isoform of Serine/arginine-rich splicing factor 5 OS=Cricetulus griseus OX=10029 GN=Srsf5 PE=3 SV=1 CANONICAL=A0A9J7G145-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H1N7", "url": "https://www.uniprot.org/uniprotkb/G3H1N7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"A0A9J7G145", "url": "https://omabrowser.org/oma/group/A0A9J7G145/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZK82-1", "protein_name": "Serine/arginine-rich splicing factor 5", "gene_name": "SRSF5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGRGRGRYSDRFSSRRPRSDRRSAPPLRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYSDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRSRSSSRSRSRSRSRSRKSYSRSRSRSRSKSRSVSRSPMPEKSQKRGSSSRSKSPSSVDRQRSRSRSRSVDSGN", "length": 265 }, "evidence": [ { "id": "A0A9J7G145", "url": "https://omabrowser.org/oma/group/A0A9J7G145/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O35326-1", "protein_name": "Serine/arginine-rich splicing factor 5", "gene_name": "Srsf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHRSRSRSRSRTRSSSRSRSRSRSRRSKSYSRSRSRSRSRSKSRSGSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN", "length": 269 }, "evidence": [ { "id": "A0A9J7G145", "url": "https://omabrowser.org/oma/group/A0A9J7G145/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q09167-1", "protein_name": "Serine/arginine-rich splicing factor 5", "gene_name": "Srsf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHRSRSRSRSRTRSSSRSRSRSRSRRSKSYSRSRSRSRSRSKSRSGSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN", "length": 269 }, "evidence": [ { "id": "A0A9J7G145", "url": 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"id": "A0A9J7G145", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G145", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G145", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G145", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G145" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613757.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016829864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829864" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Smco4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK8", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVK8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100753911", "url": "https://www.ncbi.nlm.nih.gov/gene/100753911", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753911", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753911", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FFIYANT", "url": "https://omabrowser.org/oma/group/FFIYANT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FVK8", "url": "https://www.orthodb.org/?gene=A0A9J7FVK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JN61", "url": "https://www.orthodb.org/?gene=A0A9J7JN61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34644", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34644", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34644:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34644:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016829864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829864", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FU85", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU85-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JN61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JN61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H6P4", "url": "https://www.uniprot.org/uniprotkb/G3H6P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H6P4-1", "url": "https://www.uniprot.org/uniprotkb/G3H6P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIAEESQEQTQRCAGSASRRCSNLDCLSGLGQLTVRSSPGSWRRITQITLTGSRLTDITEFEVKRPPAWTEDCGPSSKTSLGTSSHHHLAKMRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPTVTE", "length": 150, "header": "tr|A0A9J7FVK8-1|A0A9J7FVK8_CRIGR Isoform 1 of Single-pass membrane and coiled-coil domain-containing protein 4 OS=Cricetulus griseus OX=10029 GN=Smco4 PE=3 SV=1 CANONICAL=A0A9J7FVK8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FU85-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK8/entry#A0A9J7FU85-1", "sequence": { "sequence": "MTLGITQITLTGSRLTDITEFEVKRPPAWTEDCGPSSKTSLGTSSHHHLAKMRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPTVTE", "length": 110, "header": "tr|A0A9J7FU85-1|A0A9J7FVK8_CRIGR Computationally mapped isoform of Single-pass membrane and coiled-coil domain-containing protein 4 OS=Cricetulus griseus OX=10029 GN=Smco4 PE=3 SV=1 CANONICAL=A0A9J7FVK8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK8/entry#A0A9J7FVK8-1", "sequence": { "sequence": "MIAEESQEQTQRCAGSASRRCSNLDCLSGLGQLTVRSSPGSWRRITQITLTGSRLTDITEFEVKRPPAWTEDCGPSSKTSLGTSSHHHLAKMRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPTVTE", "length": 150, "header": "tr|A0A9J7FVK8-1|A0A9J7FVK8_CRIGR Isoform 1 of Single-pass membrane and coiled-coil domain-containing protein 4 OS=Cricetulus griseus OX=10029 GN=Smco4 PE=3 SV=1 CANONICAL=A0A9J7FVK8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JN61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK8/entry#A0A9J7JN61-1", "sequence": { "sequence": "MGCHLGITQITLTGSRLTDITEFEVKRPPAWTEDCGPSSKTSLGTSSHHHLAKMRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPTVTE", "length": 112, "header": "tr|A0A9J7JN61-1|A0A9J7JN61_CRIGR Computationally mapped isoform of Single-pass membrane and coiled-coil domain-containing protein 4 OS=Cricetulus griseus OX=10029 GN=Smco4 PE=3 SV=1 CANONICAL=A0A9J7FVK8-1" }, "locus": {} }, { "isoform_ac": "G3H6P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK8/entry#G3H6P4-1", "sequence": { "sequence": "MRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPTVTE", "length": 59, "header": "tr|G3H6P4-1|A0A9J7FVK8_CRIGR Computationally mapped isoform of Single-pass membrane and coiled-coil domain-containing protein 4 OS=Cricetulus griseus OX=10029 GN=Smco4 PE=3 SV=1 CANONICAL=A0A9J7FVK8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H6P4", "url": "https://www.uniprot.org/uniprotkb/G3H6P4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H6P4", "url": "https://www.uniprot.org/uniprotkb/G3H6P4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753911", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753911", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FNY6-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4", "gene_name": "SMCO4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVVLIVVFVYVATRPTITE", "length": 59 }, "evidence": [ { "id": "A0A9J7FVK8", "url": "https://omabrowser.org/oma/group/A0A9J7FVK8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q32PD9-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4", "gene_name": "SMCO4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRQLKGKPKKETSRDKKERKQAMQEARRQITTVVLPTLAVVVLLIVVFVYVATRPASTE", "length": 59 }, "evidence": [ { "id": "A0A9J7FVK8", "url": "https://omabrowser.org/oma/group/A0A9J7FVK8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8SY72-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRQLKGKVKETRKQKKERKLDNLETQAKIRTVVLPALGVLAVFLVLFVYLKTRPAVLA", "length": 58 }, "evidence": [ { "id": "A0A9J7FVK8", "url": "https://omabrowser.org/oma/group/A0A9J7FVK8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9JIS3-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4", "gene_name": "Smco4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPAVTE", "length": 59 }, "evidence": [ { "id": "A0A9J7FVK8", "url": "https://omabrowser.org/oma/group/A0A9J7FVK8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRQ5-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4", "gene_name": "SMCO4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRQLKGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPTITE", "length": 59 }, "evidence": [ { "id": "A0A9J7FVK8", "url": "https://omabrowser.org/oma/group/A0A9J7FVK8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GG67-1", "protein_name": "Single-pass membrane and coiled-coil domain-containing protein 4", "gene_name": "SMCO4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRQLRGKPKKETSKDKKERKQAMQEARQQITTVVLPTLAVVVLLIVVFVYVATRPNTTE", "length": 59 }, "evidence": [ { "id": "A0A9J7FVK8", "url": "https://omabrowser.org/oma/group/A0A9J7FVK8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FXZ8-1", "uniprot_ac": "A0A9J7FXZ8", "uniprot_id": "A0A9J7FXZ8_CRIGR", "mass": { "chemical_mass": 53250.0, "monoisotopic_mass": 53250.0 }, "refseq": { "ac": "XP_027270966", "name": "transcriptional coactivator YAP1 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270966" }, "gene_names": [ { "name": "Yap1", "type": "recommended", "evidence": [ { "id": "A0A9J7FXZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8" } ] }, { "name": "Yap1", "type": "synonym", "evidence": [ { "id": "XP_027270966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270966" } ] } ], "protein_names": [ { "name": "Transcriptional coactivator YAP1", "type": "recommended", "evidence": [ { "id": "A0A9J7FXZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8/entry#names_and_taxonomy" } ] }, { "name": "Protein yorkie homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7FXZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8/entry#names_and_taxonomy" } ] }, { "name": "Yes-associated protein YAP65 homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7FXZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8/entry#names_and_taxonomy" } ] }, { "name": "transcriptional coactivator YAP1 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_027270966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270966" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270966" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Yap1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8", "locus": {} } ], "crossref": [ { "id": "A0A9J7FXZ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FXZ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761993", "url": "https://www.ncbi.nlm.nih.gov/gene/100761993", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761993", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761993", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FXZ8", "url": "https://www.orthodb.org/?gene=A0A9J7FXZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17616", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17616", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17616:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17616:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270966", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LVL1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LYN3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LYN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQI1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPAQQPPPQPAPQGPVPPSAPAPPSGTPAAPPAPPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTVVSGPAATPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQLNVPTPASTAVPQTLMNSASGPLPDGWEQAMTQDGDVYYINHKNKTTSWLDPRLDPRFAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGNSSQQQQMQLQQLQMEKERLRLKQQELLRQVRPQAIRNINPSTANAPKCQELALRSQLPTLEQDGGTQNAVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQSRFPDYLEAIPGTNVDLGTLEGDAMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL", "length": 494, "header": "tr|A0A9J7FXZ8-1|A0A9J7FXZ8_CRIGR Isoform 1 of Transcriptional coactivator YAP1 OS=Cricetulus griseus OX=10029 GN=Yap1 PE=3 SV=1 CANONICAL=A0A9J7FXZ8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LVL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8/entry#A0A8C2LVL1-1", "sequence": { "sequence": "MEPAQQPPPQPAPQGPVPPSAPAPPSGTPAAPPAPPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTVVSGPAATPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQLNVPTPASTAVPQTLMNSASGPLPDGWEQAMTQDGDVYYINHKNKTTSWLDPRLDPRFAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGNSSQQQQMQLQQLQMEKERLRLKQQELLRQELALRSQLPTLEQDGGTQNAVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQSRFPDYLEAIPGTNVDLGTLEGDAMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL", "length": 474, "header": "tr|A0A8C2LVL1-1|A0A8C2LVL1_CRIGR Computationally mapped isoform of Transcriptional coactivator YAP1 OS=Cricetulus griseus OX=10029 GN=Yap1 PE=3 SV=1 CANONICAL=A0A9J7FXZ8-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LYN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8/entry#A0A8C2LYN3-1", "sequence": { "sequence": "MEPAQQPPPQPAPQGPVPPSAPAPPSGTPAAPPAPPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTVVSGPAATPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQLNVPTPASTAVPQTLMNSASGPLPDGWEQAMTQDGDVYYINHKNKTTSWLDPRLDPRFAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGNSSQQQQMQLQQLQMEKERLRLKQQELLRQAIRNINPSTANAPKCQELALRSQLPTLEQDGGTQNAVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQSRFPDYLEAIPGTNVDLGTLEGDAMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL", "length": 490, "header": "tr|A0A8C2LYN3-1|A0A9J7FXZ8_CRIGR Computationally mapped isoform of Transcriptional coactivator YAP1 OS=Cricetulus griseus OX=10029 GN=Yap1 PE=3 SV=1 CANONICAL=A0A9J7FXZ8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8/entry#A0A9J7FXZ8-1", "sequence": { "sequence": "MEPAQQPPPQPAPQGPVPPSAPAPPSGTPAAPPAPPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTVVSGPAATPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQLNVPTPASTAVPQTLMNSASGPLPDGWEQAMTQDGDVYYINHKNKTTSWLDPRLDPRFAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGNSSQQQQMQLQQLQMEKERLRLKQQELLRQVRPQAIRNINPSTANAPKCQELALRSQLPTLEQDGGTQNAVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQSRFPDYLEAIPGTNVDLGTLEGDAMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL", "length": 494, "header": "tr|A0A9J7FXZ8-1|A0A9J7FXZ8_CRIGR Isoform 1 of Transcriptional coactivator YAP1 OS=Cricetulus griseus OX=10029 GN=Yap1 PE=3 SV=1 CANONICAL=A0A9J7FXZ8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXZ8/entry#A0A9J7JQI1-1", "sequence": { "sequence": "MEPAQQPPPQPAPQGPVPPSAPAPPSGTPAAPPAPPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTVVSGPAATPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQLNVPTPASTAVPQTLMNSASGPLPDGWEQAMTQDGDVYYINHKNKTTSWLDPRLDPRFAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGNSSQQQQMQLQQLQMEKERLRLKQQELLRQVRPQELALRSQLPTLEQDGGTQNAVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQSRFPDYLEAIPGTNVDLGTLEGDAMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL", "length": 478, "header": "tr|A0A9J7JQI1-1|A0A9J7JQI1_CRIGR Computationally mapped isoform of Transcriptional coactivator YAP1 OS=Cricetulus griseus OX=10029 GN=Yap1 PE=3 SV=1 CANONICAL=A0A9J7FXZ8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 140, "start_aa": "Thr", "end_pos": 140, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr140", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 28, "start_aa": "Thr", "end_pos": 28, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr28", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273716" } ] }, { "annotation": "Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G153", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G153#function" }, { "database": "UniProtKB", "id": "ARBA00058654", "url": "https://www.uniprot.org/uniprotkb/ARBA00058654#function" }, { "database": "UniProtKB", "id": "A0A9J7G1D6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D6#function" }, { "database": "UniProtKB", "id": "A0A9J7JPE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mta3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6", "locus": {} } ], "crossref": [ { "id": "A0A9J7G1J6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G1J6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00202", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00202", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04709", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04709", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765306", "url": "https://www.ncbi.nlm.nih.gov/gene/100765306", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765306", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765306", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G1J6", "url": "https://www.orthodb.org/?gene=A0A9J7G1J6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10865", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10865", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10865:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10865:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01448", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01448", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G153", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G153", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G153-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G153-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1D6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5W3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H103", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H103", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H103-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H103-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JR77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JR77-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSF2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K997", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K997", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K997-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K997-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRKGLKKKKRSQHPPCLSASIPALFLTFPDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDASKIRMVNSLIFGRGGHELRSLQLETVKEIAFVASVGQRAESPSPRASSTSE", "length": 657, "header": "tr|A0A9J7G1J6-1|A0A9J7G1J6_CRIGR Isoform 1 of Metastasis-associated protein MTA3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G153-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7G153-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAECKTLFNS", "length": 513, "header": "tr|A0A9J7G153-1|A0A9J7G1J6_CRIGR Computationally mapped isoform of Metastasis-associated protein MTA3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1D6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7G1D6-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDASKIRMVNSLIFGRGGHELRSLQLETVKEIAFVASVGQRAESPSPRASSTSE", "length": 637, "header": "tr|A0A9J7G1D6-1|A0A9J7G1J6_CRIGR Computationally mapped isoform of Metastasis-associated protein MTA3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7G1J6-1", "sequence": { "sequence": "MRKGLKKKKRSQHPPCLSASIPALFLTFPDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDASKIRMVNSLIFGRGGHELRSLQLETVKEIAFVASVGQRAESPSPRASSTSE", "length": 657, "header": "tr|A0A9J7G1J6-1|A0A9J7G1J6_CRIGR Isoform 1 of Metastasis-associated protein MTA3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7G1N8-1", "sequence": { "sequence": "MRKGLKKKKRSQHPPCLSASIPALFLTFPDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDGRIISALPSSCDHVGLGFCP", "length": 625, "header": "tr|A0A9J7G1N8-1|A0A9J7G1N8_CRIGR Computationally mapped isoform of Metastasis-associated protein MTA3 isoform X8 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G5W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7G5W3-1", "sequence": { "sequence": "MRKGLKKKKRSQHPPCLSASIPALFLTFPDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDASKIRMVNSLIFGRGGHELRSLQLETVKEIAFVASVGQRAESPSPRASSTSE", "length": 656, "header": "tr|A0A9J7G5W3-1|A0A9J7G5W3_CRIGR Computationally mapped isoform of Metastasis-associated protein MTA3 isoform X3 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H103-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7H103-1", "sequence": { "sequence": "MGLCNVQPCFSKMTTFSAEKKLFVAFKPGGLNLTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDASKIRMVNSLIFGRGGHELRSLQLETVKEIAFVASVGQRAESPSPRASSTSE", "length": 638, "header": "tr|A0A9J7H103-1|A0A9J7H103_CRIGR Computationally mapped isoform of Metastasis-associated protein MTA3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7JJC3-1", "sequence": { "sequence": "MRKGLKKKKRSQHPPCLSASIPALFLTFPDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDGPERWLSR", "length": 613, "header": "tr|A0A9J7JJC3-1|A0A9J7JJC3_CRIGR Computationally mapped isoform of Metastasis-associated protein MTA3 isoform X9 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7JPE8-1", "sequence": { "sequence": "MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDASKIRMVNSLIFGRGGHELRSLQLETVKEIAFVASVGQRAESPSPRASSTSE", "length": 636, "header": "tr|A0A9J7JPE8-1|A0A9J7JPE8_CRIGR Computationally mapped isoform of Metastasis-associated protein MTA3 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JR77-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7JR77-1", "sequence": { "sequence": "MLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDASKIRMVNSLIFGRGGHELRSLQLETVKEIAFVASVGQRAESPSPRASSTSE", "length": 581, "header": "tr|A0A9J7JR77-1|A0A9J7JR77_CRIGR Computationally mapped isoform of Metastasis-associated protein MTA3 isoform X11 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7JSF2-1", "sequence": { "sequence": "MRKGLKKKKRSQHPPCLSASIPALFLTFPDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDELTCCVSD", "length": 613, "header": "tr|A0A9J7JSF2-1|A0A9J7JSF2_CRIGR Computationally mapped isoform of Metastasis-associated protein MTA3 isoform X10 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K997-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6/entry#A0A9J7K997-1", "sequence": { "sequence": "MRKGLKKKKRSQHPPCLSASIPALFLTFPDYVYFENSSSNPYLIRRIEELNKTASGNVEAKVVCFYRRRDISNTLIMLADKHAKETEEETEMTVEADLTEKQKHQLKHRELFLSRQYESLPATHIRGKCSVALLNETESVLSYLDKEDAFFYSLVYDPSVKTLLADKGEIRVGPKYQADIPDMLPEGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCRDEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPTYSKPNPNQISTSNGKSGTVNGAVGTTFQPQNTLLGRACESCYATQSHQWYSWGPPNMQCRLCATCWLYWKKYGGLKMPTQSEEQKSPSPSAEDPRVRSHLSRQAMQGMPVRNTGSPKSAVKTRQAFFLHTTYFTKIARQVCKNTLRLRQAARRPFVAINYAAIRAEYADRHAELAGSPLKSKSTRKPLSCIIGYLEIHPAKKPNVIRSPPSLQTPTTKRMLTAPNHTSLSILGKRNYSHHNGLDGLGEPCLPPAGKTPVKKQRAWDHPAPSFRSVTPAQDLNSGQKTGTAS", "length": 652, "header": "tr|A0A9J7K997-1|A0A9J7K997_CRIGR Computationally mapped isoform of Metastasis-associated protein MTA3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Mta3 PE=3 SV=1 CANONICAL=A0A9J7G1J6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G153", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G153" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G153", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G153" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765306", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765306", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" } ], "pmid": "" }, { "name": "NuRD complex", "id": "GO:0016581", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016581", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G1J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" }, { "id": "PS51038", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51038" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAH", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 167, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G1J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" }, { "id": "PS51156", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELM2", "eco_id": "ECO_0000259", "start_pos": 168, "end_pos": 279, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G1J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1J6" }, { "id": "PS51293", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SANT", "eco_id": "ECO_0000259", "start_pos": 286, "end_pos": 338, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 597, "end_pos": 599 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FWV4-1", "uniprot_ac": "A0A9J7FWV4", "uniprot_id": "A0A9J7FWV4_CRIGR", "mass": { "chemical_mass": 65405.0, "monoisotopic_mass": 65405.0 }, "refseq": { "ac": "XP_027270018", "name": "paxillin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270018" }, "gene_names": [ { "name": "Pxn", "type": "recommended", "evidence": [ { "id": "A0A9J7FWV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" } ] }, { "name": "Pxn", "type": "synonym", "evidence": [ { "id": "XP_027270018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270018" } ] } ], "protein_names": [ { "name": "Paxillin", "type": "recommended", "evidence": [ { "id": "A0A9J7FWV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4/entry#names_and_taxonomy" } ] }, { "name": "paxillin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027270018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270018" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270018" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pxn", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4", "locus": {} } ], "crossref": [ { "id": "A0A9J7FWV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FWV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09336", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09336", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09338", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09338", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09411", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09411", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760740", "url": "https://www.ncbi.nlm.nih.gov/gene/100760740", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760740", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760740", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MTGPHYV", "url": "https://omabrowser.org/oma/group/MTGPHYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FWK2", "url": "https://www.orthodb.org/?gene=A0A9J7FWK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FWV4", "url": "https://www.orthodb.org/?gene=A0A9J7FWV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24216:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24216:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03535", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03535", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270018", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QFD1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QFD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QFD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QFD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWKLQVSSPIEAADALLADLESTTSHISKRPVFLSEEPPYSYPTGNHTYQETAVPPPVPPPPSSEALNGTILDPLDQWQPSGSRYTHQQPPSPSPVYSSSAKTSGASNPQDSALCSRAGEEEHVYSFPNKHKSAEPSPTMMSSSLGNNLSELDRLLLELNAVQHNPSGFPADEANSSPPLPGALSPLYGVPESNSTLGGKTGPLMKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSSQQQTRISASSATRELDELMASLSDFKMHGLEQRVDGERQWAAGWPPSSRQSSPEGQDEGGFMAQGKTGSSPPPGGLSKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHSLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQSCFLKLFC", "length": 598, "header": "tr|A0A9J7FWV4-1|A0A9J7FWV4_CRIGR Isoform 1 of Paxillin OS=Cricetulus griseus OX=10029 GN=Pxn PE=3 SV=1 CANONICAL=A0A9J7FWV4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QFD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4/entry#A0A8C2QFD1-1", "sequence": { "sequence": "MDDLDALLADLESTTSHISKRPVFLSEEPPYSYPTGNHTYQETAVPPPVPPPPSSEALNGTILDPLDQWQPSGSRYTHQQPPSPSPVYSSSAKTSGASNPQDSALCSRAGEEEHVYSFPNKHKSAEPSPTMMSSSLGNNLSELDRLLLELNAVQHNPSGFPADEANSSPPLPGALSPLYGVPESNSTLGGKTGPLMKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSSQQQTRISASSATRELDELMASLSDFKMHGLEQRVDGERQWAAGWPPSSRQSSPEGQDEGGFMAQGKTGSSPPPGGLSKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHSLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQSCFLKLFC", "length": 589, "header": "tr|A0A8C2QFD1-1|A0A9J7FWV4_CRIGR Computationally mapped isoform of Paxillin OS=Cricetulus griseus OX=10029 GN=Pxn PE=3 SV=1 CANONICAL=A0A9J7FWV4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4/entry#A0A9J7FWK2-1", "sequence": { "sequence": "MWKLQVSSPIEAADALLADLESTTSHISKRPVFLSEEPPYSYPTGNHTYQETAVPPPVPPPPSSEALNGTILDPLDQWQPSGSRYTHQQPPSPSPVYSSSAKTSGASNPQDSALCSRAGEEEHVYSFPNKHKSAEPSPTMMSSSLGNNLSELDRLLLELNAVQHNPSGFPADEANSSPPLPGALSPLYGVPESNSTLGGKTGPLMKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSSQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSPPPGGLSKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHSLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQSCFLKLFC", "length": 564, "header": "tr|A0A9J7FWK2-1|A0A9J7FWK2_CRIGR Computationally mapped isoform of Paxillin OS=Cricetulus griseus OX=10029 GN=Pxn PE=3 SV=1 CANONICAL=A0A9J7FWV4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4/entry#A0A9J7FWV4-1", "sequence": { "sequence": "MWKLQVSSPIEAADALLADLESTTSHISKRPVFLSEEPPYSYPTGNHTYQETAVPPPVPPPPSSEALNGTILDPLDQWQPSGSRYTHQQPPSPSPVYSSSAKTSGASNPQDSALCSRAGEEEHVYSFPNKHKSAEPSPTMMSSSLGNNLSELDRLLLELNAVQHNPSGFPADEANSSPPLPGALSPLYGVPESNSTLGGKTGPLMKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSSQQQTRISASSATRELDELMASLSDFKMHGLEQRVDGERQWAAGWPPSSRQSSPEGQDEGGFMAQGKTGSSPPPGGLSKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHSLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQSCFLKLFC", "length": 598, "header": "tr|A0A9J7FWV4-1|A0A9J7FWV4_CRIGR Isoform 1 of Paxillin OS=Cricetulus griseus OX=10029 GN=Pxn PE=3 SV=1 CANONICAL=A0A9J7FWV4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QFD1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QFD1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QFD1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QFD1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760740", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760740", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SQ71-1", "protein_name": "Paxillin", "gene_name": "PXN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPVPPPPSSEALNGSVLDPLDPWPPSTSRFTHQQPQSSSPVYGSSAKTSSASNPQDGGGPPCPRAGEEDHVYSFPNKQKSAEPSPTVMSSSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGPLSTHYGVPENNSLLGGKAGALTKEKPKRNGGRGLEDLRPSVENLLDELESSVPSPVPTITVNQGEMSSPQRVTSSQQQTRISASSATRELDELMASLSDFKTSSSSAVALSSSGLPPGSAPSSHHSLSPPPPAGSSGGLPPPRKPSPQGHSHTLGVLCAGQVAPGQLDLAGFGVMPDTPNSRFPSTEGWPGLLSVESQAHVWRDPPDLVEELCRVPPGHILPYPGGTGPQDPGAPQAPLANALHPEEAVAATWQGPWALGVLKPEPPQGAAPNFQEVTEPAVVAVDRQAVFPDTWSLTEERGCQERARPEPGAPESGRHTPVEDEQLGGETPLAGGLVRPARGPETPRRPEGTTEVTTEARMDRPELPRAVAVDMPSTTERISTSSQIRSVIRRSRETGHAHPMSREPSPRRRLDPATLSRTPSQERLITELQGRLGIRPEAEEATGAAGASTEDWLTEGVVITVQPRGRRAGGQLVEKVVFPPGSPIPLRRTFSVLPSPLPPPSPLLQHRKDASSASSSPPLPSPPTPCGPSGVQSTGTGPQGVGVQGPAPCVAAPRSVRSIGCQTDEDPLFPPMQIQDLEQRADGELCWAAGWPLNGRQSGPEGQDMGGFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVHGSFFEHEGQPYCEAHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC", "length": 1066 }, "evidence": [ { "id": "A0A9J7FWV4", "url": "https://omabrowser.org/oma/group/A0A9J7FWV4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "transforming growth factor beta receptor signaling pathway", "id": "GO:0007179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007179", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" } ], "pmid": "" }, { "name": "substrate adhesion-dependent cell spreading", "id": "GO:0034446", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034446", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" } ], "pmid": "" }, { "name": "endothelial cell migration", "id": "GO:0043542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043542", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FWV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWV4" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 363, "end_pos": 422, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 175, "end_pos": 177 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G0F6-1", "uniprot_ac": "A0A9J7G0F6", "uniprot_id": "A0A9J7G0F6_CRIGR", "mass": { "chemical_mass": 59305.0, "monoisotopic_mass": 59305.0 }, "refseq": { "ac": "XP_007650330", "name": "HMG box-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650330" }, "gene_names": [ { "name": "Hbp1", "type": "recommended", "evidence": [ { "id": "A0A9J7G0F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6" } ] }, { "name": "Hbp1", "type": "synonym", "evidence": [ { "id": "XP_007650330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650330" } ] } ], "protein_names": [ { "name": "HMG box-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7G0F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6/entry#names_and_taxonomy" } ] }, { "name": "HMG box transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0A9J7G0F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6/entry#names_and_taxonomy" } ] }, { "name": "HMG box-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007650330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650330" } ] }, { "name": "High mobility group box transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0A9J7G0F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615165.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_007650330.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007650330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650330" } ] }, { "annotation": "Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QI27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI27#function" }, { "database": "UniProtKB", "id": "ARBA00025095", "url": "https://www.uniprot.org/uniprotkb/ARBA00025095#function" }, { "database": "UniProtKB", "id": "A0A9J7G0F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6#function" }, { "database": "UniProtKB", "id": "A0A9J7JRS0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRS0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hbp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6", "locus": {} } ], "crossref": [ { "id": "A0A9J7G0F6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G0F6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21988", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21988", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766157", "url": "https://www.ncbi.nlm.nih.gov/gene/100766157", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766157", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766157", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDDSTVF", "url": "https://omabrowser.org/oma/group/CDDSTVF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QI27", "url": "https://www.orthodb.org/?gene=A0A8C2QI27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G0F6", "url": "https://www.orthodb.org/?gene=A0A9J7G0F6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15499:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15499:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007650330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650330", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QI27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QI27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRS0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRS0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSYHIPAMLSEHHNMVWEVKTNQMPNAVQKLLLVMDKRASGMNDSLELLQCNENLPSSPGYNSCDEHMELDDLPELQAVQSDPTQSAIYQLSSDVSHQDYPRPSWSQDTSDITENTHREDEVDWLTELANIATSPQSPLMQCSFYGRSPPVHIIATSKSLHSYARPPPVSSSSKSGPAFPHDHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTIWHCFLKGTRLCFHKESNKEWQDVEDFARTEGCDNEEEIQMGTHKGYGSDGLKLLSHEESISFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDICLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGPGSAQECASSECSKSCGSPGSSQLSSDSLYAKAVKSHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "length": 530, "header": "tr|A0A9J7G0F6-1|A0A9J7G0F6_CRIGR Isoform 1 of HMG box-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Hbp1 PE=4 SV=1 CANONICAL=A0A9J7G0F6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QI27-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6/entry#A0A8C2QI27-1", "sequence": { "sequence": "MATGLSEHHNMVWEVKTNQMPNAVQKLLLVMDKRASGMNDSLELLQCNENLPSSPGYNSCDEHMELDDLPELQAVQSDPTQSAIYQLSSDVSHQDYPRPSWSQDTSDITENTHREDEVDWLTELANIATSPQSPLMQCSFYGRSPPVHIIATSKSLHSYARPPPVSSSSKSGPAFPHDHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTIWHCFLKGTRLCFHKESNKEWQDVEDFARTEGCDNEEEIQMGTHKGYGSDGLKLLSHEESISFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDICLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGPGSAQECASSECSKSCGSPGSSQLSSDSLYAKAVKSHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "length": 525, "header": "tr|A0A8C2QI27-1|A0A9J7G0F6_CRIGR Computationally mapped isoform of HMG box-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Hbp1 PE=4 SV=1 CANONICAL=A0A9J7G0F6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G0F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6/entry#A0A9J7G0F6-1", "sequence": { "sequence": "MGSYHIPAMLSEHHNMVWEVKTNQMPNAVQKLLLVMDKRASGMNDSLELLQCNENLPSSPGYNSCDEHMELDDLPELQAVQSDPTQSAIYQLSSDVSHQDYPRPSWSQDTSDITENTHREDEVDWLTELANIATSPQSPLMQCSFYGRSPPVHIIATSKSLHSYARPPPVSSSSKSGPAFPHDHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTIWHCFLKGTRLCFHKESNKEWQDVEDFARTEGCDNEEEIQMGTHKGYGSDGLKLLSHEESISFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDICLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGPGSAQECASSECSKSCGSPGSSQLSSDSLYAKAVKSHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "length": 530, "header": "tr|A0A9J7G0F6-1|A0A9J7G0F6_CRIGR Isoform 1 of HMG box-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Hbp1 PE=4 SV=1 CANONICAL=A0A9J7G0F6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6/entry#A0A9J7JRS0-1", "sequence": { "sequence": "MVWEVKTNQMPNAVQKLLLVMDKRASGMNDSLELLQCNENLPSSPGYNSCDEHMELDDLPELQAVQSDPTQSAIYQLSSDVSHQDYPRPSWSQDTSDITENTHREDEVDWLTELANIATSPQSPLMQCSFYGRSPPVHIIATSKSLHSYARPPPVSSSSKSGPAFPHDHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTIWHCFLKGTRLCFHKESNKEWQDVEDFARTEGCDNEEEIQMGTHKGYGSDGLKLLSHEESISFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDICLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGPGSAQECASSECSKSCGSPGSSQLSSDSLYAKAVKSHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "length": 515, "header": "tr|A0A9J7JRS0-1|A0A9J7JRS0_CRIGR Computationally mapped isoform of HMG box-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Hbp1 PE=4 SV=1 CANONICAL=A0A9J7G0F6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QI27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI27" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QI27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI27" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766157", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766157", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y8L1-1", "protein_name": "HMG box-containing protein 1", "gene_name": "HBP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATGSSDTLEHPNMVWEVKTNQMPNAVQKLLLVVDKRTSGMNESLELLKCNENLPSSPGYASCDEHMELDDLPELQAVQTDSAPSALFQLGTDVSHQERSRPSWNQHTSNSDSESAHSCENGVNWLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPGSSKNDPNFSKSDLDETPVRHERTNSESESGIFCMSSLSDDDDLGWCHSWPSTVWHCFLKGSRLCFHKGRNKEWQDIEDFARSEGCGKEDNLSVSAYKGYGSDGLKLISHEESISFGESVLKLTFDPGTVEDGLLTVECRLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEMHLGDLCLPPGHPDAINFDDSGVFDTFKSYDFTPLDSSAVYVLSSMARQRRASLSCGGSNNQDAERSECSTKNCAATAASHLSSTSLYSKAGKSHGSGTASTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "length": 530 }, "evidence": [ { "id": "A0A9J7G0F6", "url": "https://omabrowser.org/oma/group/A0A9J7G0F6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9TTW0-1", "protein_name": "HMG box-containing protein 1", "gene_name": "HBP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTAGAVNRPIPACGEPTGLALPASSPGLRVGTSERHNMVWEVKSNQMPDAVQKLLLVMDKRAPGVSDSLQLLQCKETLPSSPGYNSCDEHMELDDLPELQAVQSDPTPSAIYQLSSDVSHQEYPRPSWNQNTSEISENTYRENEVDWLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVASSKGEPAFPHHWKEQTPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTAWHCFLKGTRLCFHKGSNKEWQNVEDFARTEGCDNEEDLQMGTHKDYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDVCLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGPGGQDFERSGFSKNCGSPGSSQLSSSSLYAKAVKTHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "length": 549 }, "evidence": [ { "id": "A0A9J7G0F6", "url": "https://omabrowser.org/oma/group/A0A9J7G0F6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O60381-1", "protein_name": "HMG box-containing protein 1", "gene_name": "HBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVWEVKTNQMPNAVQKLLLVMDKRASGMNDSLELLQCNENLPSSPGYNSCDEHMELDDLPELQAVQSDPTQSGMYQLSSDVSHQEYPRSSWNQNTSDIPETTYRENEVDWLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVSSSSKSEPAFPHHHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTVWHCFLKGTRLCFHKGSNKEWQDVEDFARAEGCDNEEDLQMGIHKGYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEVHIGDVCLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGPGGQDFARSGFSKNCGSPGSSQLSSNSLYAKAVKNHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "length": 514 }, "evidence": [ { "id": "A0A9J7G0F6", "url": "https://omabrowser.org/oma/group/A0A9J7G0F6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62661-1", "protein_name": "HMG box-containing protein 1", "gene_name": "Hbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVWEVKTNQRPHAVQRLLLVMDERATGVSDSLELLQCNENVPSSPGYNSCDEHMELDDLPELQAVQSDPTQSAIYQLSSDVSHQEYPRPSWSQNTSDIPENTHREDEVDWLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVSSAKSGPAFPHDHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTVWHCFLKGTRLCFHKESKKEWQDVEDFARAASCDEEEIQMGTHKGYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDVCLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGPGTGQEFAGSEFSKSCGSPGSSQLSSSSLYTKAVKSHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "length": 513 }, "evidence": [ { "id": "A0A9J7G0F6", "url": "https://omabrowser.org/oma/group/A0A9J7G0F6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R316-1", "protein_name": "HMG box-containing protein 1", "gene_name": "Hbp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVWEVKTNQMPNAVQKLLLVMDKRAPGMSDSLELLQCNENLPSSPGYNSCDEHMELDDLPELQAVQSDPTQSAIYQLSSDVSHQEYPRSSWSQNTSDIPENTHREDEVDWLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVSSSSKSGPAFPHDHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTIWHCFLKGTRLCFHKESNKEWQDVEDFARAASCDNEEEIQMGTHKGYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDVCLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGGPGTGQEFSGSEFSKSCGSPGSSQLSSSSLYAKAVKSHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH", "length": 516 }, "evidence": [ { "id": "A0A9J7G0F6", "url": "https://omabrowser.org/oma/group/A0A9J7G0F6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G0F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0F6" }, { "id": "PS51148", "database": "PROSITE", "url": 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sorting-associated protein 29", "type": "recommended", "evidence": [ { "id": "A0A9J7FZP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4/entry#names_and_taxonomy" } ] }, { "name": "Vesicle protein sorting 29", "type": "synonym", "evidence": [ { "id": "A0A9J7FZP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4/entry#names_and_taxonomy" } ] }, { "name": "vacuolar protein sorting-associated protein 29 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027269850", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269850" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269850", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269850" } ] }, { "annotation": "Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the Csubcomplex and the retriever subcomplex. Component of the retriever complex, which is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos. Component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. In the endosomes, retriever complex drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to snx17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling. The recruitment of the retriever complex to the endosomal membrane involves Cand WASH complexes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QJK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJK3#function" }, { "database": "UniProtKB", "id": "RU362040", "url": "https://www.uniprot.org/uniprotkb/RU362040#function" }, { "database": "UniProtKB", "id": "A0A9J7FZP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4#function" }, { "database": "UniProtKB", "id": "A0A9J7JQC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQC6#function" }, { "database": "UniProtKB", "id": "A0A8C2MKC8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKC8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4" } ], "common_name": "Chinese hamster", 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"length": 201, "header": "tr|A0A9J7FZP4-1|A0A9J7FZP4_CRIGR Isoform 1 of Vacuolar protein sorting-associated protein 29 OS=Cricetulus griseus OX=10029 GN=Vps29 PE=3 SV=1 CANONICAL=A0A9J7FZP4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4/entry#A0A9J7JQC6-1", "sequence": { "sequence": "MVSTAAAAAAAAAATRLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS", "length": 197, "header": "tr|A0A9J7JQC6-1|A0A9J7JQC6_CRIGR Computationally mapped isoform of Vacuolar protein sorting-associated protein 29 OS=Cricetulus griseus OX=10029 GN=Vps29 PE=3 SV=1 CANONICAL=A0A9J7FZP4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A9J7FZP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4" } ], "pmid": "" }, { "name": "retromer complex", "id": "GO:0030904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030904", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FZP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZP4" }, { "id": "PF12850", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calcineurin-like phosphoesterase", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 175, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVV8-1", "uniprot_ac": "A0A9J7FVV8", "uniprot_id": "A0A9J7FVV8_CRIGR", "mass": { "chemical_mass": 34463.0, "monoisotopic_mass": 34463.0 }, "refseq": { "ac": "XP_007646595", "name": "general transcription factor IIH subunit 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646595" }, "gene_names": [ { "name": "Gtf2h3", "type": "recommended", "evidence": [ { "id": "A0A9J7FVV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ] }, { "name": "Gtf2h3", "type": "synonym", "evidence": [ { "id": "XP_007646595", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646595" } ] } ], "protein_names": [ { "name": "General transcription factor IIH subunit 3", "type": "recommended", "evidence": [ { "id": "A0A9J7FVV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8/entry#names_and_taxonomy" } ] }, { "name": "General transcription factor IIH polypeptide 3", "type": "synonym", "evidence": [ { "id": "A0A9J7FVV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8/entry#names_and_taxonomy" } ] }, { "name": "general transcription factor IIH subunit 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007646595", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646595" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614436.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007646595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646595" } ] }, { "annotation": "Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QJU0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJU0#function" }, { "database": "UniProtKB", "id": "RU368090", "url": "https://www.uniprot.org/uniprotkb/RU368090#function" }, { "database": "UniProtKB", "id": "ARBA00057028", "url": "https://www.uniprot.org/uniprotkb/ARBA00057028#function" }, { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gtf2h3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVV8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVV8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768069", "url": "https://www.ncbi.nlm.nih.gov/gene/100768069", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768069", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768069", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QGCDITS", "url": "https://omabrowser.org/oma/group/QGCDITS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QJU0", "url": "https://www.orthodb.org/?gene=A0A8C2QJU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FVV8", "url": "https://www.orthodb.org/?gene=A0A9J7FVV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12831", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12831", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12831:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12831:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03850", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03850", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007646595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646595", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QJU0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QJU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAADAEDELNLLVIIVDTNPIWWGKQALKGSQFTLSKCMDAVMVLANSHLFMHRSNQLAVIASHIQESRFLYPGKNGRLGDFFGDPGNPFPDCNPSGSKDGKYELLTAANDVIAEEIKDLMTKSDIKGQHTETLLAGSLAKALCYIHRMNKAVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACILDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPIHVDYRAACFCHRSLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKQKVSL", "length": 310, "header": "tr|A0A9J7FVV8-1|A0A9J7FVV8_CRIGR Isoform 1 of General transcription factor IIH subunit 3 OS=Cricetulus griseus OX=10029 GN=Gtf2h3 PE=3 SV=1 CANONICAL=A0A9J7FVV8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QJU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8/entry#A0A8C2QJU0-1", "sequence": { "sequence": "MAADEDELNLLVIIVDTNPIWWGKQALKGSQFTLSKCMDAVMVLANSHLFMHRSNQLAVIASHIQESRFLYPGKNGRLGDFFGDPGNPFPDCNPSGSKDGKYELLTAANDVIAEEIKDLMTKSDIKGQHTETLLAGSLAKALCYIHRMNKAVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACILDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPIHVDYRAACFCHRSLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKQKVSL", "length": 309, "header": "tr|A0A8C2QJU0-1|A0A9J7FVV8_CRIGR Computationally mapped isoform of General transcription factor IIH subunit 3 OS=Cricetulus griseus OX=10029 GN=Gtf2h3 PE=3 SV=1 CANONICAL=A0A9J7FVV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8/entry#A0A9J7FVV8-1", "sequence": { "sequence": "MAADAEDELNLLVIIVDTNPIWWGKQALKGSQFTLSKCMDAVMVLANSHLFMHRSNQLAVIASHIQESRFLYPGKNGRLGDFFGDPGNPFPDCNPSGSKDGKYELLTAANDVIAEEIKDLMTKSDIKGQHTETLLAGSLAKALCYIHRMNKAVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACILDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPIHVDYRAACFCHRSLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKQKVSL", "length": 310, "header": "tr|A0A9J7FVV8-1|A0A9J7FVV8_CRIGR Isoform 1 of General transcription factor IIH subunit 3 OS=Cricetulus griseus OX=10029 GN=Gtf2h3 PE=3 SV=1 CANONICAL=A0A9J7FVV8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QJU0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJU0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QJU0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJU0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768069", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768069", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AH26-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "GTF2H3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVSDEDELNLLVIIVDTNPIWWGKQALKESQGSNLRFFCVCANTRCPVSLFYLLPFTLSKCIDAVMVLGNSHLFMNRSNKLAVIASHIQESRFLYPGKNGRLGDFFGDPGNPSSEFNPSGSKDGKYELLTAANDVIAEEIKDLMTKSDIEGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPIHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKLKMSS", "length": 333 }, "evidence": [ { "id": "A0A9J7FVV8", "url": "https://omabrowser.org/oma/group/A0A9J7FVV8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5WWE3-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "gtf2h3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASDDDINILVIVLDVNPVWWGQQAQREPKFTLSACLDSLMVLANAHLVMSRTNKLAVITSLYHESHFLYPSKQWRSGEEISANPDGKYELLSVTNDLFAEEIRNLMERAEVSGSQTETLLAVSLARALCYINRISKDVQAGQEVKSRILVIKAAEDSTSQYMNFMNVIFAAQKKNILIDACVLDSDSGLLQQACDITGGLYLRVPQKVALTQYLLWVFLPDAEQRSQLLLPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKMPLPQMAKTKKKKLKTAN", "length": 296 }, "evidence": [ { "id": "A0A9J7FVV8", "url": "https://omabrowser.org/oma/group/A0A9J7FVV8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q05B56-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "GTF2H3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVSDEDELNLLVIIVDTNPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVIASHIQESRFLYPGKNGRLGDFFGDPGNPSSEFTPSGSKDGKYELLTAANEVIAEEIKDLMTKSDIEGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKLKMSS", "length": 309 }, "evidence": [ { "id": "A0A9J7FVV8", "url": "https://omabrowser.org/oma/group/A0A9J7FVV8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q12004-1", "protein_name": "General transcription and DNA repair factor IIH subunit TFB4", "gene_name": "TFB4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDAISDPTFKHARSRKQVTEESPSLLTVIIEIAPKLWTTFDEEGNEKGSIIKVLEALIVFLNAHLAFNSANKVAVIAAYSQGIKYLYPESTSALKASESENKTRSDLKIINSDMYRRFRNVDETLVEEIYKLFELEKKQIEQNSQRSTLAGAMSAGLTYVNRISKESVTTSLKSRLLVLTCGSGSSKDEIFQYIPIMNCIFSATKMKCPIDVVKIGGSKESTFLQQTTDATNGVYLHVESTEGLIQYLATAMFIDPSLRPIIVKPNHGSVDFRTSCYLTGRVVAVGFICSVCLCVLSIIPPGNKCPACDSQFDEHVIAKLKRKPVVPRLKAKKKVTKP", "length": 338 }, "evidence": [ { "id": "A0A9J7FVV8", "url": "https://omabrowser.org/oma/group/A0A9J7FVV8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q13889-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "GTF2H3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSDEDELNLLVIVVDANPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVIASHIQESRFLYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMTKSDIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKLKVSA", "length": 308 }, "evidence": [ { "id": "A0A9J7FVV8", "url": "https://omabrowser.org/oma/group/A0A9J7FVV8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q561R7-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "Gtf2h3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAADEDELNLLVIIVDTNPIWWGKQALKESQFTLSKCMDAVMVLANAHLFMNRSNQLAVIASHIQESRFLYPGKNGRLGDFFGDPGNALPDCNPSGSKDGKYELLTAANEVIAEEIKDLMTKSDIKGQHTETLLAGSLAKALCYIHRASKAVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPIHVDYRAACFCHRSLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKQKVSL", "length": 309 }, "evidence": [ { "id": "A0A9J7FVV8", "url": "https://omabrowser.org/oma/group/A0A9J7FVV8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86IB5-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "gtf2h3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNEGSAVINEDDDTSLLVVILDCNVYSWGNREKSLQDAISGMNDDNDSSSRYNGSTTIGNNNNNNNNNNSNNNNNVNKRLINTSKNNYIGFNKFLEHFMVFINAYLMLNQENQLAIICSKIGESSFVFPQSNIDQYQQEQQELEQRQLNENGELLPTPNKTIQGQILAKLQKLDLEIKHDQTDILSSSFSASMSIALCYINRIKRETPTIKPRILVFNISPDVSSQYISVMNCIFSSQKQSIPVDSCILSQSDSTFLQQASHLTSGIYLKPQKQELLSQYLLTTFLLDTLSRKSLAYPTLKSVDYRASCFCHKRIVDIGYVCSVCLSIFCGHSSSCSTCGTKFSLKIDLRKQLNNNPTTTTSATSTVNNKS", "length": 372 }, "evidence": [ { "id": "A0A9J7FVV8", "url": "https://omabrowser.org/oma/group/A0A9J7FVV8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8LF41-1", "protein_name": "General transcription and DNA repair factor IIH subunit TFB4", "gene_name": "TFB4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MPAIASKQYSDDVSLLVLLLDTNPLFWSTTSITFSQFLSHVLAFLNAVLGLNQLNQVVVIATGYSSCDYIYDSSLTSNHGNFESNGTGMPAIFGSLLKKLEEFVTKDEELSKEEVSEDRIPSCLLSGSLSMALCYIQRVFRSGHLHPQPRILCLQGSPDGPEQYVAVMNSIFSAQRLMVPIDSCYIGVQNSAFLQQASYITGGVHHTPKQLDGLFQYLTTIFATDLHSRGFVQLPKPIGVDFRASCFCHKKTIDMGYICSVCLSIFCEHHKKCSTCGSVFGQSKLDDASSASDKKRKAPST", "length": 301 }, "evidence": [ { "id": "A0A9J7FVV8", "url": "https://omabrowser.org/oma/group/A0A9J7FVV8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VD76-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "Gtf2h3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADEDELNLLVIIVDTNPIWWGKQALKESQFTLSKCMDAVMVLANSHLFMNRSNQLAVIASHIQESRLLYPGKNGGLGDFFGDPGNALPDCNPSGSKDGKYELLTVANEVIAEEIKDLMTKSDIKGQHTETLLAGSLAKALCYIHRVNKAVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPIHVDYRAACFCHRSLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKQKVSL", "length": 309 }, "evidence": [ { "id": "A0A9J7FVV8", "url": "https://omabrowser.org/oma/group/A0A9J7FVV8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VPX4-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "Tfb4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEADQAASKEAESCIDLLVIVLDTNPSQHFVRQNPQNLTQILEAVIAFGNAHLMQKAQNKLAVVSCSHHATNFLYPLPRRQVELRQVDGQYEAFNLVEKTVKQQLGSILMNAPRLSAPCESLLAGSMSMALCYISRLQRNLAPGVKMHSRILVVTGSNECASQYMTFMNVFFTAQKLGITIDTCALDKTLSLLQQGCDITSGQFLKVTQLDGLLQYLLWVFLPAPQIRHKLVLPPPPKVDYRASCFCHRELIDIGYVCSVCLSVFCKYSPICTTCHTIFKNPGPLPIKGKKKKKTDKQM", "length": 299 }, "evidence": [ { "id": "A0A9J7FVV8", "url": "https://omabrowser.org/oma/group/A0A9J7FVV8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "transcription preinitiation complex", "id": "GO:0097550", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097550", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "pmid": "" }, { "name": "transcription factor TFIID complex", "id": "GO:0005669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005669", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "pmid": "" }, { "name": "core TFIIH complex portion of holo TFIIH complex", "id": "GO:0000438", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000438", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "pmid": "" }, { "name": "transcription factor TFIIH holo complex", "id": "GO:0005675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005675", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "pmid": "" }, { "name": "transcription factor TFIIH core complex", "id": "GO:0000439", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000439", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "pmid": "" }, { "name": "RNA polymerase II general transcription initiation factor activity", "id": "GO:0016251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 279, "end_pos": 281 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"mass": { "chemical_mass": 52706.0, "monoisotopic_mass": 52706.0 }, "refseq": { "ac": "XP_003501434", "name": "forkhead box protein N3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501434" }, "gene_names": [ { "name": "Foxn3", "type": "recommended", "evidence": [ { "id": "A0A9J7G2R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2" } ] }, { "name": "Foxn3", "type": "synonym", "evidence": [ { "id": "XP_003501434", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501434" } ] } ], "protein_names": [ { "name": "Forkhead box protein N3", "type": "recommended", "evidence": [ { "id": "A0A9J7G2R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2/entry#names_and_taxonomy" } ] }, { "name": "Checkpoint suppressor 1", "type": "synonym", "evidence": [ { "id": "A0A9J7G2R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2/entry#names_and_taxonomy" } ] }, { "name": "forkhead box protein N3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003501434", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501434" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613847.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501434" } ] }, { "annotation": "Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QLY9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLY9#function" }, { "database": "UniProtKB", "id": "ARBA00034657", "url": "https://www.uniprot.org/uniprotkb/ARBA00034657#function" }, { "database": "UniProtKB", "id": "A0A9J7G2R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2#function" }, { "database": "UniProtKB", "id": "A0A9J7G5T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5T0#function" }, { "database": "UniProtKB", "id": "A0A9J7K9U8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9U8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Foxn3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2", "locus": {} } ], "crossref": [ { "id": "cd20059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768709", "url": "https://www.ncbi.nlm.nih.gov/gene/100768709", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768709", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768709", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XSIGKGS", "url": "https://omabrowser.org/oma/group/XSIGKGS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G2R2", "url": "https://www.orthodb.org/?gene=A0A9J7G2R2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13962", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13962", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13962:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13962:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501434", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QLY9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QLY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5T0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9U8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9U8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPVMPASKKPESSGISVSSGLSHCYPGSGFSKALQEDDDLDFPLPDIRLEEGTMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPPPTPQAYQSTSGPPIWPGSTFFKRNGALLQDPDIDAASAMMLLNSPPEIQAGFSPGVIQNGARVLSRGLFPGVRPLPITPIGMTAAIRNSISSCRMRTESEPPCGSPVVSGDPKEDHNYSSAKSSNARSTSPASDSISSSSSSSADDHYEFATKGSQEGSEGSFQSHESHSETEEDDRKPSQKEAKDALGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETTKN", "length": 480, "header": "tr|A0A9J7G2R2-1|A0A9J7G2R2_CRIGR Isoform 1 of Forkhead box protein N3 OS=Cricetulus griseus OX=10029 GN=Foxn3 PE=4 SV=1 CANONICAL=A0A9J7G2R2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QLY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2/entry#A0A8C2QLY9-1", "sequence": { "sequence": "MGPVMPASKKPESSGISVSSGLSHCYPGSGFSKALQEDDDLDFPLPDIRLEEGTMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPPPTPQAYQSTSGPPIWPGSTFFKRNGALLQVSPGVIQNGARVLSRGLFPGVRPLPITPIGMTAAIRNSISSCRMRTESEPPCGSPVVSGDPKEDHNYSSAKSSNARSTSPASDSISSSSSSSADDHYEFATKGSQEGSEGSFQSHESHSETEEDDRKPSQKEAKDALGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETTKN", "length": 458, "header": "tr|A0A8C2QLY9-1|A0A9J7G2R2_CRIGR Computationally mapped isoform of Forkhead box protein N3 OS=Cricetulus griseus OX=10029 GN=Foxn3 PE=4 SV=1 CANONICAL=A0A9J7G2R2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2/entry#A0A9J7G2R2-1", "sequence": { "sequence": "MGPVMPASKKPESSGISVSSGLSHCYPGSGFSKALQEDDDLDFPLPDIRLEEGTMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPPPTPQAYQSTSGPPIWPGSTFFKRNGALLQDPDIDAASAMMLLNSPPEIQAGFSPGVIQNGARVLSRGLFPGVRPLPITPIGMTAAIRNSISSCRMRTESEPPCGSPVVSGDPKEDHNYSSAKSSNARSTSPASDSISSSSSSSADDHYEFATKGSQEGSEGSFQSHESHSETEEDDRKPSQKEAKDALGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETTKN", "length": 480, "header": "tr|A0A9J7G2R2-1|A0A9J7G2R2_CRIGR Isoform 1 of Forkhead box protein N3 OS=Cricetulus griseus OX=10029 GN=Foxn3 PE=4 SV=1 CANONICAL=A0A9J7G2R2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G5T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2/entry#A0A9J7G5T0-1", "sequence": { "sequence": "MGPVMPASKKPESSGISVSSGLSHCYPGSGFSKALQEDDDLDFPLPDIRLEEGTMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPPPTPQAYQSTSGPPIWPGSTFFKRNGALLQDPDIDAASAMMLLNSPPEIQAVSPGVIQNGARVLSRGLFPGVRPLPITPIGMTAAIRNSISSCRMRTESEPPCGSPVVSGDPKEDHNYSSAKSSNARSTSPASDSISSSSSSSADDHYEFATKGSQEGSEGSFQSHESHSETEEDDRKPSQKEAKDALGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETTKN", "length": 479, "header": "tr|A0A9J7G5T0-1|A0A9J7G5T0_CRIGR Computationally mapped isoform of Forkhead box protein N3 OS=Cricetulus griseus OX=10029 GN=Foxn3 PE=4 SV=1 CANONICAL=A0A9J7G2R2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2/entry#A0A9J7K9U8-1", "sequence": { "sequence": "MGPVMPASKKPESSGISVSSGLSHCYPGSGFSKALQEDDDLDFPLPDIRLEEGTMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPPPTPQAYQSTSGPPIWPGSTFFKRNGALLQGIASAVAGCGLRVSRRVAPQWSVVTPRRIITTVVPSPPMLEAPLPPATPSLPPPPPQLTTTTSLPPRGARRAVREASRAMRATVRPRRMTGNPARRRPRMPWGTADTHPSTRSDSTSPRQGRSPATHCPSKRDAQKNPLRATMRR", "length": 385, "header": "tr|A0A9J7K9U8-1|A0A9J7K9U8_CRIGR Computationally mapped isoform of Forkhead box protein N3 OS=Cricetulus griseus OX=10029 GN=Foxn3 PE=4 SV=1 CANONICAL=A0A9J7G2R2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 213, "start_aa": "Thr", "end_pos": 213, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 289, "start_aa": "Thr", "end_pos": 289, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr289", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QLY9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLY9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QLY9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLY9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768709", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768709", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYT8-1", "protein_name": "Forkhead box protein N3", "gene_name": "Foxn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPVMPASKKPESSGISVSSGLSQRYRGSGFSKALQEDDDLDFPLPDIRLEEGTMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPPPTPQAYQSTSGPPIWPGSTFFKRNGALLQDPDIDAASAMMLLNSPPEIQAGFSPGVIQNGARVLSRGLFPGARPLPITPIGMTAAIRNSITSCRVRTESEPPCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYEFATKGSQEGSEGSFQSHESHSEPEEDDRKPSQKEGKDALGDSGYASQHRKRQHLAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETAKN", "length": 479 }, "evidence": [ { "id": "A0A9J7G2R2", "url": "https://omabrowser.org/oma/group/A0A9J7G2R2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1LX68-1", "protein_name": "Forkhead box protein N3", "gene_name": "FOXN3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPVMPPSKKPESSGISVSSGLSQCYRGSGFSKALQEDDDLDFPLPDIRLEEGAMEDEELTNLNWLHESKNLLKSFGDSVLRSVSPVQDPDDDPPPSPAHSDVPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHSNVFNTPPASPQAYQSTSGPPLWPGSTFFKRNGALLQDPDIDAATAMMLLNTPPEIHAGFPPGVIQNGTRVLSRGLFPGVRPLPVTPIGMTAAVRNGLPGCRLRTESEPACGSPVVSGDPKEDHTYSSAKAAAARSASPASDCASSSSADEPDEVAAKGGPEGSEGSCPSRESHSEPEEDGRPRGPREAPGDGGPAHKKRPPAAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETAKN", "length": 480 }, "evidence": [ { "id": "A0A9J7G2R2", "url": "https://omabrowser.org/oma/group/A0A9J7G2R2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8D0JTS1-1", "protein_name": "Forkhead box protein N3", "gene_name": "FOXN3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGPVMPPSKKPESSGISVSSGLSQCYRGSSFSKALQEDDDLDFSLPDIRLEEGAMEDEELTNLNWLHESKNLLKSFGDSVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHSHSNVFNTPPASPQAYQSTSGPPIWPGSTFFKRNGALLQDPDIDAASAMMLLNTPPEIQAGFPPGVIQNGARVLSRGLFPGVRPLPITPIGMTAAVRNGLTSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSHARSTSPASDCVSSSSADDHYEFATKGSQEGSEGSFQSHESHSETEEDDRKCSPKEAKDALGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETTKN", "length": 485 }, "evidence": [ { "id": "A0A9J7G2R2", "url": "https://omabrowser.org/oma/group/A0A9J7G2R2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M9PED3-1", "protein_name": "Forkhead box protein N3", "gene_name": "foxn3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGPVMPPSKKPESSGVSVASGLSQFYQASSITRALQEAEEMDLALPTIKLEKGSVEDEELTNLNWLHESKNLLNSFGDPVLRSVSPVQDLDDDTPPSPAHSDLPYDAKQNPNCKPPYSFSCLIFMAIEDAPSKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKDRSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPYSQVFTTPPTSPQAYQSMSSPPIWPGSPFYRKNKGVLLQVPQGVIQNGARMMSQGLFPGIRPLPINPIVSRTAAVRSVLGYRITSDTEPTQNSPLATSDPKEDHTYSFAKSSGSDAEEEAQCDGSELNFHTNETGSDAEDDDKSKIKKEPKEWSVDALALAQHKKRQLLTKVKQRVASDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGVRACLNNITNRTAKGQKEQK", "length": 441 }, "evidence": [ { "id": "A0A9J7G2R2", "url": "https://omabrowser.org/oma/group/A0A9J7G2R2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O00409-1", "protein_name": "Forkhead box protein N3", "gene_name": "FOXN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPVMPPSKKPESSGISVSSGLSQCYGGSGFSKALQEDDDLDFSLPDIRLEEGAMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPHPHVFNTPPTCPQAYQSTSGPPIWPGSTFFKRNGALLQDPDIDAASAMMLLNTPPEIQAGFPPGVIQNGARVLSRGLFPGVRPLPITPIGVTAAMRNGITSCRMRTESEPSCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSADDHYEFATKGSQEGSEGSEGSFRSHESPSDTEEDDRKHSQKEPKDSLGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETTKN", "length": 490 }, "evidence": [ { "id": "A0A9J7G2R2", "url": "https://omabrowser.org/oma/group/A0A9J7G2R2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q499D0-1", "protein_name": "Forkhead box protein N3", "gene_name": "Foxn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPVMPASKKAESSGISVSSGLSQRYRGSGFSKALQEDDDLDFPLPDIRLEEGAMEDEELTNLNWLHESKNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPEYRQNLIQALKKTPYHPPPTPQAYQSTSGPPIWPGSTFFKRNGALLQVSPGVIQNGARVLSRGLFPGVRPLPITPIGMTAAIRNSITSCRMRTESEPPCGSPVVSGDPKEDHNYSSAKSSTARSTSPTSDSISSSSSSADDHYEFATKGSQEGSEGSFQSHESHSEPEEEDRKPSPKEGKDALGDSGYASQHKKRQHFAKARKVPSDTLPLKKRRTEKPPESDDEEMKEAAGSLLHLAGIRSCLNNITNRTAKGQKEQKETAKN", "length": 457 }, "evidence": [ { "id": "A0A9J7G2R2", "url": "https://omabrowser.org/oma/group/A0A9J7G2R2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2" } ], "pmid": "" }, { "name": "cis-regulatory region sequence-specific DNA binding", "id": "GO:0000987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000987", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2" } ], "pmid": "" }, { "name": "mitotic G2 DNA damage checkpoint signaling", "id": "GO:0007095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007095", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2R2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G2R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2R2" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 201, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 213, 289 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 465, "end_pos": 467 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G1D9-1", "uniprot_ac": "A0A9J7G1D9", "uniprot_id": "A0A9J7G1D9_CRIGR", "mass": { "chemical_mass": 141920.0, "monoisotopic_mass": 141920.0 }, "refseq": { "ac": "XP_027271213", "name": "serine/threonine-protein kinase ULK4 isoform X9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271213" }, "gene_names": [ { "name": "Ulk4", "type": "recommended", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "name": "Ulk4", "type": "synonym", "evidence": [ { "id": "XP_027271213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271213" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase ULK4 isoform X9", "type": "synonym", "evidence": [ { "id": "XP_027271213", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271213" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271213" } ] }, { "annotation": "May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF6#function" }, { "database": "UniProtKB", "id": "ARBA00054867", "url": "https://www.uniprot.org/uniprotkb/ARBA00054867#function" }, { "database": "UniProtKB", "id": "A0A9J7G2N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2N5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ulk4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9", "locus": {} } ], "crossref": [ { "id": "A0A9J7G1D9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G1D9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14010", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14010", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773013", "url": "https://www.ncbi.nlm.nih.gov/gene/100773013", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773013", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773013", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G1D9", "url": "https://www.orthodb.org/?gene=A0A9J7G1D9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46240:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46240:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271213", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QMQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QMQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYF6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0C0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0C2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2N5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXN9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K518", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K518", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K518-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K518-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTEKCKRPEITNWVRLTHDIKHKNIVAFHEWYETSNHLWMVVELCTGGSLETVIAQDQNLPEDVVREFGVDLVTGLHHLHRLGILFCDLTPGKILLEGPGTLKFSNFCLAKVEGESLEEFFALVAAEEGSGDSGENTLKKNMKNRVRGSLIYSAPEIVKGTDFSVTSDLWSLGCLLYEMFSGKAPFFSETVSELVEKILYEDPLPPVPKDSAFPKASSDFIDLLHGLLQKDPQKRLSWDGVLQHSFWKDSLRREDLDLASEDCSFSSRNVMECSGPNDSREFLQSPQNGQGKGQKGAHRLSQSFRLDTPTELRPKSTKGGQLNESIFLLSSRPTPRTSAMVGLSPGEGEDTSSPQTSPLSKMTCGRLSRGTLESQMRVLIYTDSDLVITPIIDNPKIIKQPTIKFDPKILHLPAYSVDKLQVLKDQDWNDFLQQVCSQIDSIEKSAGTLRAKLNLLCYLCVVATHREVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVIGLLALHTAELQENVPVIEAITLLTELIRENFRSSKLKQCLLPTLGQLIYLVATQEEKKQHSRDYWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFITGEVGPVLWHLFRHSTVDSLRITAMSALCRITRQSPAAFQSVIEKVGLNAVISSLASSICKVQQYMLTLFAAMLSCGVHLQRLIQEKDFVSTIIRLLDSPSTAIRAKAFLVLLYTLIYNRDMLLLSCQARLVMYIERDSRKTSPGKELQAGSEYLARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPLVVTEDFLFSYGTILSHIKSVDLGETNIDGAIGMAASEEFIKITLSAFEAVIQYPVLLADYRSTVIDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQELEDGDEEASCDSDSSLLALLRDELLPQYEHILMEPDPVPACALKLLVAMTEHNPTFARLVEESKLVPLVFEVILEHQENILGNTMQSVIALLNNLVAYKDSNMKLLYEQGLVGHVCHMFIETATLCLDGDNKNSTEPAAALLVSLLDILLGMLTHTSNVVRQALQAQKSGSRGDTQAAEDLLLLSKPLTDLISLLIPLLPNEDPEISEVSSKCLSILVQLYGGENPDSLSPENLETFADLLVTKEDPKDQKLLLRILRRMVTSNGKHLESLKSTGSLLQVLERLAPAHSSPIDTVVASLALELLQAVGH", "length": 1275, "header": "tr|A0A9J7G1D9-1|A0A9J7G1D9_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Ulk4 PE=4 SV=1 CANONICAL=A0A9J7G1D9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QMQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9/entry#A0A8C2QMQ9-1", "sequence": { "sequence": "MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTEKCKRPEITNWVRLTHDIKHKNIVAFHEWYETSNHLWMVVELCTGGSLETVIAQDQNLPEDVVREFGVDLVTGLHHLHRLGILFCDLTPGKILLEGPGTLKFSNFCLAKVEGESLEEFFALVAAEEGSGDSGENTLKKNMKNRVRGSLIYSAPEIVKGTDFSVTSDLWSLGCLLYEMFSGKAPFFSETVSELVEKILYEDPLPPVPKDSAFPKASSDFIDLLHGLLQKDPQKRLSWDGVLQHSFWKDSLRREDLDLASEDCSFSRNVMECSGPNDSREFLQSPQNGQGKGQKGAHRLSQSFRLDTPTELRPKSTKGGQLNESIFLLSSRPTPRTSAMVGLSPGEGEDTSSPQTSPLSKMTCGRLSRGTLESQMRVLIYTDSDLVITPIIDNPKIIKQPTIKFDPKILHLPAYSVDKLQVLKDQDWNDFLQQVCSQIDSIEKSAGTLRAKLNLLCYLCVVATHREVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVIGLLALHTAELQENVPVIEAITLLTELIRENFRSSKLKQCLLPTLGQLIYLVATQEEKKQHSRDYWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFITGEVGPVLWHLFRHSTVDSLRITAMSALCRITRQSPAAFQSVIEKVGLNAVISSLASSICKVQQYMLTLFAAMLSCGVHLQRLIQEKDFVSTIIRLLDSPSTAIRAKAFLVLLYTLIYNRDMLLLSCQARLVMYIERDSRKTSPGKELQAGSEYLARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPLVVTEDFLFSYGTILSHIKSVDLGETNIDGAIGMAASEEFIKITLSAFEAVIQYPVLLADYRSTVIDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQELEDGDEEASCDSDSSLLALLRDELLPQYEHILMEPDPVPACALKLLVAMTEHNPTFARLVEESKLVPLVFEVILEHQENILGNTMQSVIALLNNLVAYKDSNMKLLYEQGLVGHVCHMFIETATLCLDGDNKNSTEPAAALLVSLLDILLGMLTHTSNVVRQALQAQKSGSRGDTQAAEDLLLLSKPLTDLISLLIPLLPNEDPEISEVSSKCLSILVQLYGGENPDSLSPENLETFADLLVTKEDPKDQKLLLRILRRMVTSNGKHLESLKSTGSLLQVLERLAPAHSSPIDTVVASLALELLQAVGH", "length": 1274, "header": "tr|A0A8C2QMQ9-1|A0A9J7G1D9_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Ulk4 PE=4 SV=1 CANONICAL=A0A9J7G1D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9/entry#A0A9J7FYF6-1", "sequence": { "sequence": "MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTEKCKRPEITNWVRLTHDIKHKNIVAFHEWYETSNHLWMVVELCTGGSLETVIAQDQNLPEDVVREFGVDLVTGLHHLHRLGILFCDLTPGKILLEGPGTLKFSNFCLAKVEGESLEEFFALVAAEEGSGDSGENTLKKNMKNRVRGSLIYSAPEIVKGTDFSVTSDLWSLGCLLYEMFSGKAPFFSETVSELVEKILYEDPLPPVPKDSAFPKASSDFIDLLHGLLQKDPQKRLSWDGVLQHSFWKDSLRREDLDLASEDCSFSSRNVMECSGPNDSREFLQSPQNGQGKGQKGAHRLSQSFRLDTPTELRPKSTKGGQLNESIFLLSSRPTPRTSAMVGLSPGEGEDTSSPQTSPLSKMTCGRLSRGTLESQMRVLIYTDSDLVITPIIDNPKIIKQPTIKFDPKILHLPAYSVDKLQVLKDQDWNDFLQQVCSQIDSIEKSAGTLRAKLNLLCYLCVVATHREVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVIGLLALHTAELQENVPVIEAITLLTELIRENFRSSKLKQCLLPTLGQLIYLVATQEEKKQHSRDYWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFITGEVGPVLWHLFRHSTVDSLRITAMSALCRITRQSPAAFQSVIEKVGLNAVISSLASSICKVQQYMLTLFAAMLSCGVHLQRLIQEKDFVSTIIRLLDSPSTAIRAKAFLVLLYTLIYNRDMLLLSCQARLVMYIERDSRKTSPGKELQAGSEYLARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPLVVTEDFLFSYGTILSHIKSVDLGETNIDGAIGMAASEEFIKITLSAFEAVIQYPVLLADYRSTVIDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQELEDGDEEASCDSDSSLLALLRDELLPQYEHILMEPDPVPACALKLLVAMTEHNPTFASHGVEWRFKPGVATLRTFKVSFICRHALTLESPGKGDPQMSTGLHHMSCRCSCRAFPDC", "length": 1082, "header": "tr|A0A9J7FYF6-1|A0A9J7FYF6_CRIGR Computationally mapped isoform of Serine/threonine-protein kinase ULK4 OS=Cricetulus griseus OX=10029 GN=Ulk4 PE=4 SV=1 CANONICAL=A0A9J7G1D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G0C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9/entry#A0A9J7G0C0-1", "sequence": { "sequence": "MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTEKCKRPEITNWVRLTHDIKHKNIVAFHEWYETSNHLWMVVELCTGGSLETVIAQDQNLPEDVVREFGVDLVTGLHHLHRLGILFCDLTPGKILLEGPGTLKFSNFCLAKVEGESLEEFFALVAAEEGSGDSGENTLKKNMKNRVRGSLIYSAPEIVKGTDFSVTSDLWSLGCLLYEMFSGKAPFFSETVSELVEKILYEDPLPPVPKDSAFPKASSDFIDLLHGLLQKDPQKRLSWDGVLQHSFWKDSLRREDLDLASEDCSFSSRNVMECSGPNDSREFLQSPQNGQGKGQKGAHRLSQSFRLDTPTELRPKSTKGGQLNESIFLLSSRPTPRTSAMVGLSPGEGEDTSSPQTSPLSKMTCGRLSRGTLESQMRVLIYTDSDLVITPIIDNPKIIKQPTIKFDPKILHLPAYSVDKLQVLKDQDWNDFLQQVCSQIDSIEKSAGTLRAKLNLLCYLCVVATHREVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVIGLLALHTAELQENVPVIEEEKKQHSRDYWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFITGEVGPVLWHLFRHSTVDSLRITAMSALCRITRQSPAAFQSVIEKVGLNAVISSLASSICKVQQYMLTLFAAMLSCGVHLQRLIQEKDFVSTIIRLLDSPSTAIRAKAFLVLLYTLIYNRDMLLLSCQARLVMYIERDSRKTSPGKELQAGSEYLARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPLVVTEDFLFSYGTILSHIKSVDLGETNIDGAIGMAASEEFIKITLSAFEAVIQYPVLLADYRSTVIDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQELEDGDEEASCDSDSSLLALLRDELLPQYEHILMEPDPVPACALKLLVAMTEHNPTFARLVEESKLVPLVFEVILEHQENILGNTMQSVIALLNNLVAYKDSNMKLLYEQGLVGHVCHMFIETATLCLDGDNKNSTEPAAALLVSLLDILLGMLTHTSNVVRQALQAQKSGSRGDTQAAEDLLLLSKPLTDLISLLIPLLPNEDPEISEVSSKCLSILVQLYGGENPDSLSPENLETFADLLVTKEDPKDQKLLLRILRRMVTSNGKHLESLKSTGSLLQVLERLAPAHSSPIDTVVASLALELLQAVGH", "length": 1239, "header": "tr|A0A9J7G0C0-1|A0A9J7G0C0_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Ulk4 PE=4 SV=1 CANONICAL=A0A9J7G1D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G0C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9/entry#A0A9J7G0C2-1", "sequence": { "sequence": "MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTEKCKRPEITNWVRLTHDIKHKNIVAFHEWYETSNHLWMVVELCTGGSLETVIAQDQNLPEDVVREFGVDLVTGLHHLHRLGILFCDLTPGKILLEGPGTLKFSNFCLAKVEGESLEEFFALVAAEEGSGDSGENTLKKNMKNRVRGSLIYSAPEIVKGTDFSVTSDLWSLGCLLYEMFSGKAPFFSETVSELVEKILYEDPLPPVPKDSAFPKASSDFIDLLHGLLQKDPQKRLSWDGVLQHSFWKDSLRREDLDLASEDCSFSSRNVMECSGPNDSREFLQSPQNGQGKGQKGAHRLSQSFRLDTPTELRPKSTKGGQLNESIFLLSSRPTPRTSAMVGLSPGEGEDTSSPQTSPLSKMTCGRLSRGTLESQMRVLIYTDSDLVITPIIDNPKIIKQPTIKFDPKILHLPAYSVDKLQVLKDQDWNDFLQQVCSQIDSIEKSAGTLRAKLNLLCYLCVVATHREVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVIGLLALHTAELQENVPVIEAITLLTELIRENFRSSKLKQCLLPTLGQLIYLVATQEEKKQHSRDYWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFITGEVGPVLWHLFRHSTVDSLRITAMSALCRITRQSPAAFQSVIEKVGLNAVISSLASSICKVQQYMLTLFAAMLSCGVHLQRLIQEKDFVSTIIRLLDSPSTAIRAKAFLVLLYTLIYNRDMLLLSCQARLVMYIERDSRKTSPGKELQAGSEYLARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPLVVTEDFLFSYGTILSHIKSVDLGETNIDGAIGMAASEEFIKITLSAFEAVIQYPVLLADYRSTVIDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQELEDGDEEASCDSDSSLLALLRDELLPQYEHILMEPDPVPACALKLLVAMTEHNPTFARLVEESKLVPLVFEVILEHQENILGNTMQSVIALLNNLVAYKDSNMKLLYEQGLVGHVCHMFIETATLCLDGDNKNSTEPAAALLVSLLDILLGMLTHTSNVVRQALQAQKSGSRGDTQAAEDLLLLSKPLTDLISLLIPLLPNEDPEISEVSSKCLSILVQLYGGENPDSLSPENLETFADLLVTKEDPKDQKLLLRILRRMSERAIGAFPSLVLPHAGPPHVDLRALQSVRMLLQEGMSKLRPGGRV", "length": 1272, "header": "tr|A0A9J7G0C2-1|A0A9J7G0C2_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Ulk4 PE=4 SV=1 CANONICAL=A0A9J7G1D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9/entry#A0A9J7G1D9-1", "sequence": { "sequence": "MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTEKCKRPEITNWVRLTHDIKHKNIVAFHEWYETSNHLWMVVELCTGGSLETVIAQDQNLPEDVVREFGVDLVTGLHHLHRLGILFCDLTPGKILLEGPGTLKFSNFCLAKVEGESLEEFFALVAAEEGSGDSGENTLKKNMKNRVRGSLIYSAPEIVKGTDFSVTSDLWSLGCLLYEMFSGKAPFFSETVSELVEKILYEDPLPPVPKDSAFPKASSDFIDLLHGLLQKDPQKRLSWDGVLQHSFWKDSLRREDLDLASEDCSFSSRNVMECSGPNDSREFLQSPQNGQGKGQKGAHRLSQSFRLDTPTELRPKSTKGGQLNESIFLLSSRPTPRTSAMVGLSPGEGEDTSSPQTSPLSKMTCGRLSRGTLESQMRVLIYTDSDLVITPIIDNPKIIKQPTIKFDPKILHLPAYSVDKLQVLKDQDWNDFLQQVCSQIDSIEKSAGTLRAKLNLLCYLCVVATHREVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVIGLLALHTAELQENVPVIEAITLLTELIRENFRSSKLKQCLLPTLGQLIYLVATQEEKKQHSRDYWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFITGEVGPVLWHLFRHSTVDSLRITAMSALCRITRQSPAAFQSVIEKVGLNAVISSLASSICKVQQYMLTLFAAMLSCGVHLQRLIQEKDFVSTIIRLLDSPSTAIRAKAFLVLLYTLIYNRDMLLLSCQARLVMYIERDSRKTSPGKELQAGSEYLARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPLVVTEDFLFSYGTILSHIKSVDLGETNIDGAIGMAASEEFIKITLSAFEAVIQYPVLLADYRSTVIDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQELEDGDEEASCDSDSSLLALLRDELLPQYEHILMEPDPVPACALKLLVAMTEHNPTFARLVEESKLVPLVFEVILEHQENILGNTMQSVIALLNNLVAYKDSNMKLLYEQGLVGHVCHMFIETATLCLDGDNKNSTEPAAALLVSLLDILLGMLTHTSNVVRQALQAQKSGSRGDTQAAEDLLLLSKPLTDLISLLIPLLPNEDPEISEVSSKCLSILVQLYGGENPDSLSPENLETFADLLVTKEDPKDQKLLLRILRRMVTSNGKHLESLKSTGSLLQVLERLAPAHSSPIDTVVASLALELLQAVGH", "length": 1275, "header": "tr|A0A9J7G1D9-1|A0A9J7G1D9_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Ulk4 PE=4 SV=1 CANONICAL=A0A9J7G1D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9/entry#A0A9J7G2N5-1", "sequence": { "sequence": "MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTEKCKRPEITNWVRLTHDIKHKNIVAFHEWYETSNHLWMVVELCTGGSLETVIAQDQNLPEDVVREFGVDLVTGLHHLHRLGILFCDLTPGKILLEGPGTLKFSNFCLAKVEGESLEEFFALVAAEEGSGDSGENTLKKNMKNRVRGSLIYSAPEIVKGTDFSVTSDLWSLGCLLYEMFSGKAPFFSETVSELVEKILYEDPLPPVPKDSAFPKASSDFIDLLHGLLQKDPQKRLSWDGVLQHSFWKDSLRREDLDLASEDCSFSSRNVMECSGPNDSREFLQSPQNGQGKGQKGAHRLSQSFRLDTPTELRPKSTKGGQLNESIFLLSSRPTPRTSAMVGLSPGEGEDTSSPQTSPLSKMTCGRLSRGTLESQMRVLIYTDSDLVITPIIDNPKIIKQPTIKFDPKILHLPAYSVDKLQVLKDQDWNDFLQQVCSQIDSIEKSAGTLRAKLNLLCYLCVVATHREVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVIGLLALHTAELQENVPVIEAITLLTELIRENFRSSKLKQCLLPTLGQLIYLVATQEEKKQHSRDYWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFITGEVGPVLWHLFRHSTVDSLRITAMSALCRITRQSPAAFQSVIEKVGLNAVISSLASSICKVQQYMLTLFAAMLSCGVHLQRLIQEKDFVSTIIRLLDSPSTAIRAKAFLVLLYTLIYNRDMLLLSCQARLVMYIERDSRKTSPGKELQAGSEYLARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPLVVTEDFLFSYGTILSHIKSVDLGETNIDGAIGMAASEEFIKITLSAFEAVIQYPVLLADYRSTVIDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQELEDGDEEASCDSDSSLLALLRDELLPQYEHILMEPDPVPACALKLLVAMTEHNPTFASLEDGRGTTSSGLG", "length": 1037, "header": "tr|A0A9J7G2N5-1|A0A9J7G2N5_CRIGR Computationally mapped isoform of Serine/threonine-protein kinase ULK4 OS=Cricetulus griseus OX=10029 GN=Ulk4 PE=4 SV=1 CANONICAL=A0A9J7G1D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9/entry#A0A9J7GXN9-1", "sequence": { "sequence": "MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTEKCKRPEITNWVRLTHDIKHKNIVAFHEWYETSNHLWMVVELCTGGSLETVIAQDQNLPEDVVREFGVDLVTGLHHLHRLGILFCDLTPGKILLEGPGTLKFSNFCLAKVEGESLEEFFALVAAEEGSGDSGENTLKKNMKNRVRGSLIYSAPEIVKGTDFSVTSDLWSLGCLLYEMFSGKAPFFSETVSELVEKILYEDPLPPVPKDSAFPKASSDFIDLLHGLLQKDPQKRLSWDGVLQHSFWKDSLRREDLDLASEDCSFSSRNVMECSGPNDSREFLQSPQNGQGKGQKGAHRLSQSFRLDTPTELRPKSTKGGQLNESIFLLSSRPTPRTSAMVGLSPGEGEDTSSPQTSPLSKMTCGRLSRGTLESQMRVLIYTDSDLVITPIIDNPKIIKQPTIKFDPKILHLPAYSVDKLQVLKDQDWNDFLQQVCSQIDSIEKSAGTLRAKLNLLCYLCVVATHREVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVIGLLALHTAELQENVPVIEAITLLTELIRENFRSSKLKQCLLPTLGQLIYLVATQEEKKQHSRDYWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFITGEVGPVLWHLFRHSTVDSLRITAMSALCRITRQSPAAFQSVIEKVGLNAVISSLASSICKVQQYMLTLFAAMLSCGVHLQRLIQEKDFVSTIIRLLDSPSTAIRAKAFLVLLYTLIYNRDMLLLSCQARLVMYIERDSRKTSPGKELQAGSEYLARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPLVVTEDFLFSYGTILSHIKSVDLGETNIDGAIGMAASEEFIKITLSAFEAVIQYPVLLADYRSTVIDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQELEDGDEEASCDSDSSLLALLRDELLPQYEHILMEPDPVPACALKLLVAMTEHNPTFARLVEESKLVPLVFEVILEHQENILGNTMQSVIALLNNLVAYKDSNMKLLYEQGLVGHVCHMFIETATLCLDGDNKNSTEPAAALLVSLLDILLGMLTHTSNVVRQALQAQKSGSRGDTQAAEDLLLLSKPLTDLISLLIPLLPNEDPEISEVSSKCLSILVQLYGGENPDSLSPENLETFADLLVTKEDPKDQKLLLRILRRMPGQLLTL", "length": 1233, "header": "tr|A0A9J7GXN9-1|A0A9J7GXN9_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Ulk4 PE=4 SV=1 CANONICAL=A0A9J7G1D9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K518-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9/entry#A0A9J7K518-1", "sequence": { "sequence": "MRCSQVKPRSSPKPCQNWLRRFYMKTRCRRSRRVDSAFPKASSDFIDLLHGLLQKDPQKRLSWDGVLQHSFWKDSLRREDLDLASEDCSFSSRNVMECSGPNDSREFLQSPQNGQGKGQKGAHRLSQSFRLDTPTELRPKSTKGGQLNESIFLLSSRPTPRTSAMVGLSPGEGEDTSSPQTSPLSKMTCGRLSRGTLESQMRVLIYTDSDLVITPIIDNPKIIKQPTIKFDPKILHLPAYSVDKLQVLKDQDWNDFLQQVCSQIDSIEKSAGTLRAKLNLLCYLCVVATHREVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVIGLLALHTAELQENVPVIEAITLLTELIRENFRSSKLKQCLLPTLGQLIYLVATQEEKKQHSRDYWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFITGEVGPVLWHLFRHSTVDSLRITAMSALCRITRQSPAAFQSVIEKVGLNAVISSLASSICKVQQYMLTLFAAMLSCGVHLQRLIQEKDFVSTIIRLLDSPSTAIRAKAFLVLLYTLIYNRDMLLLSCQARLVMYIERDSRKTSPGKELQAGSEYLARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPLVVTEDFLFSYGTILSHIKSVDLGETNIDGAIGMAASEEFIKITLSAFEAVIQYPVLLADYRSTVIDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQELEDGDEEASCDSDSSLLALLRDELLPQYEHILMEPDPVPACALKLLVAMTEHNPTFARLVEESKLVPLVFEVILEHQENILGNTMQSVIALLNNLVAYKDSNMKLLYEQGLVGHVCHMFIETATLCLDGDNKNSTEPAAALLVSLLDILLGMLTHTSNVVRQALQAQKSGSRGDTQAAEDLLLLSKPLTDLISLLIPLLPNEDPEISEVSSKCLSILVQLYGGENPDSLSPENLETFADLLVTKEDPKDQKLLLRILRRMVTSNGKHLESLKSTGSLLQVLERLAPAHSSPIDTVVASLALELLQAVGH", "length": 1067, "header": "tr|A0A9J7K518-1|A0A9J7K518_CRIGR Computationally mapped isoform of Serine/threonine-protein kinase ULK4 isoform X15 OS=Cricetulus griseus OX=10029 GN=Ulk4 PE=4 SV=1 CANONICAL=A0A9J7G1D9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QMQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMQ9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QMQ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMQ9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773013", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773013", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1099, "end_pos": 1101, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", 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"A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] } ] }, { "uniprot_ac": "A0A9J7G969", "gene_name": "LOC100754771", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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"https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] } ] }, { "uniprot_ac": "A0A9J7GRB5", "gene_name": "LOC113838167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] } ] }, { "uniprot_ac": "A0A9J7GRC1", "gene_name": "LOC100764806", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] } ] }, { "uniprot_ac": "A0A9J7GT89", "gene_name": "LOC100774420", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] } ] }, { "uniprot_ac": "A0A9J7GY39", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] } ] }, { "uniprot_ac": "A0A9J7GZH5", "gene_name": "Ripk4", "activity": [ { "ec_number": "2.7.11.1", "activity": 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"ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "A0A9J7H3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E2" } ] } ] }, { "uniprot_ac": "A0A9J7H3L8", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] } ] }, { "uniprot_ac": "G3IN30", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] } ] }, { "uniprot_ac": "O55076", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] } ] }, { "uniprot_ac": "P25321", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P25321", "database": "UniProtKB", 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVA2-1", "uniprot_ac": "A0A9J7FVA2", "uniprot_id": "A0A9J7FVA2_CRIGR", "mass": { "chemical_mass": 72684.0, "monoisotopic_mass": 72684.0 }, "refseq": { "ac": "XP_027265920", "name": "aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265920" }, "gene_names": [ { "name": "Arntl", "type": "recommended", "evidence": [ { "id": "A0A9J7FVA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2" } ] }, { "name": "Arntl", "type": "synonym", "evidence": [ { "id": "XP_027265920", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265920" } ] } ], "protein_names": [ { "name": "Basic helix-loop-helix ARNT-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7FVA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2/entry#names_and_taxonomy" } ] }, { "name": "Aryl hydrocarbon receptor nuclear translocator-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7FVA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2/entry#names_and_taxonomy" } ] }, { "name": "Brain and muscle ARNT-like 1", "type": "synonym", "evidence": [ { "id": "A0A9J7FVA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2/entry#names_and_taxonomy" } ] }, { "name": "aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_027265920", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265920" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027265920.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265920" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arntl", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11438", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11438", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755141", "url": "https://www.ncbi.nlm.nih.gov/gene/100755141", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001610", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001610", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FVA2", "url": "https://www.orthodb.org/?gene=A0A9J7FVA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23042", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23042", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265920", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FRE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GS41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GS41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GS41-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GS41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXH2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHDSAVPSFQWRTREWTSPQQSVTSCPQAPPTCSPVPWAPVVWTAIARGKAVPPTTSKAFGTVSSCQGMSTEHLSTAAVVPSGRESMDTDKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSTGLLSGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 664, "header": "tr|A0A9J7FVA2-1|A0A9J7FVA2_CRIGR Isoform 1 of Basic helix-loop-helix ARNT-like protein 1 OS=Cricetulus griseus OX=10029 GN=Arntl PE=4 SV=1 CANONICAL=A0A9J7FVA2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2/entry#A0A9J7FRE2-1", "sequence": { "sequence": "MADQRMDISSTISDFMSPGPTDLLSSSLGTSGVDCNRKRKGSATDYQESMDTDKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSTGLLSGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 625, "header": "tr|A0A9J7FRE2-1|A0A9J7FVA2_CRIGR Computationally mapped isoform of Basic helix-loop-helix ARNT-like protein 1 OS=Cricetulus griseus OX=10029 GN=Arntl PE=4 SV=1 CANONICAL=A0A9J7FVA2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2/entry#A0A9J7FVA2-1", "sequence": { "sequence": "MLHDSAVPSFQWRTREWTSPQQSVTSCPQAPPTCSPVPWAPVVWTAIARGKAVPPTTSKAFGTVSSCQGMSTEHLSTAAVVPSGRESMDTDKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSTGLLSGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 664, "header": "tr|A0A9J7FVA2-1|A0A9J7FVA2_CRIGR Isoform 1 of Basic helix-loop-helix ARNT-like protein 1 OS=Cricetulus griseus OX=10029 GN=Arntl PE=4 SV=1 CANONICAL=A0A9J7FVA2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GS41-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2/entry#A0A9J7GS41-1", "sequence": { "sequence": "MLHDSAVPSFQWRTREWTSPQQSVTSCPQAPPTCSPVPWAPVVWTAIARGKAVPPTTSKAFGTVSSCQGMSTEHLSTAAVVPSGRESMDTDKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSTGLLSGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 663, "header": "tr|A0A9J7GS41-1|A0A9J7GS41_CRIGR Computationally mapped isoform of Basic helix-loop-helix ARNT-like protein 1 OS=Cricetulus griseus OX=10029 GN=Arntl PE=4 SV=1 CANONICAL=A0A9J7FVA2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2/entry#A0A9J7GVX2-1", "sequence": { "sequence": "MKCNRPSVKVEDKDFASTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSTGLLSGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 376, "header": "tr|A0A9J7GVX2-1|A0A9J7GVX2_CRIGR Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X11 OS=Cricetulus griseus OX=10029 GN=Arntl PE=4 SV=1 CANONICAL=A0A9J7FVA2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2/entry#A0A9J7GXH2-1", "sequence": { "sequence": "MLHDSAVPSFQWRTREWTSPQQSVTSCPQAPPTCSPVPWAPVVWTAIARGKAVPPTTSKAFGTVSSCQGMSTEHLSTAAVVPSGRESMDTDKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSTGLLSGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL", "length": 633, "header": "tr|A0A9J7GXH2-1|A0A9J7GXH2_CRIGR Computationally mapped isoform of Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X8 OS=Cricetulus griseus OX=10029 GN=Arntl PE=4 SV=1 CANONICAL=A0A9J7FVA2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 56, "start_aa": "Thr", "end_pos": 56, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr56", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRE2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2" } ], "pmid": "" }, { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVA2" } ], "pmid": "" }, { 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}, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": 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"Ncapd3", "type": "synonym", "evidence": [ { "id": "XP_027267513", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267513" } ] } ], "protein_names": [ { "name": "Condensin-2 complex subunit D3", "type": "recommended", "evidence": [ { "id": "A0A9J7FXK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK2/entry#names_and_taxonomy" } ] }, { "name": "condensin-2 complex subunit D3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027267513", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267513" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267513", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267513" } ] }, { "annotation": "Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT55#function" }, { "database": "UniProtKB", "id": "ARBA00057333", "url": "https://www.uniprot.org/uniprotkb/ARBA00057333#function" }, { "database": "UniProtKB", "id": "A0A9J7FXK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ncapd3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK2", "locus": {} } ], "crossref": [ { "id": "100752080", "url": "https://www.ncbi.nlm.nih.gov/gene/100752080", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752080", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752080", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FXK2", "url": "https://www.orthodb.org/?gene=A0A9J7FXK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14222:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14222:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26777", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26777", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267513", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267513", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FT55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FT55-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVMALQDLGRDLQPWCPLELSLEWVNSVWELDFTETEPLDPSIEAEILETGVDAFTKLYGSLFPFATEENGSLESIWTFFVENNISINTLVALFCHFVQEAHKKGASAQNREYGLHAAGLYFLLLEIPGSVVNQVFHPVMFDKCIQILKKSWPQESNLSQKRKKEHPRSSKYNHRRGRKRGKPPRKEDNQVDEFSGEEEEEEEEIYFSARDLFQIRNVIFNLLKNFLRLLPKFSLKEKPQSIQTCIEVFVALTNFEPIPHKFLVSQARNLNGVKHISELAYYGLYLLCSPVHGEGNKVIGSIFHQMLNVILMLEVGERSRCTPLAITSQVINCRNQAVQFISSLVDELQESIFPVLGTLLQHICAKVVDKAEYRTCAAQSLVQLLNKLPSEEYATFIAWLHKYSRSSKIPHRVFTLDVALALLELPEREVDDTVLLEHQKFLKHKFFVQEIIFDRCLDKAPTVRSKALSSFAHCLESSASSTSESILEIFISSALVSGIQSCSDTLQRTSVVSSSGNWHMTQINTDGGDEREQSGERCFMAMLRKRIRDEKINVRKSALQVLVSILKHCDILSMEKDLLILQDHCRDPAVSVRKQALQSLTELVTAQPTCVPVQKAWLMGVIPVVMDCESTVQEKALECLDQLLLQNLKHHRKFHSEDRSQVLAWALLALLTTESQDLSRYLNKAFRIWSKKDKFSSTFINSVISHTDTEHSAPAWMLLSKITCSSPKLDYTKIIESWEKLSSEKSPNSNTLGYMLCVIGHIAKHLPRSTQDKIIGVVKGKLNRFQWSLELISSSVDTLQGLCRASAKTLLEEQELLKQVCGDVLSTCEHYLSNVLLKEDGAGNMNEDLVVKCIFTIGDIAQLCPAIVEKRIFLLIQSVLAASSHVDHLPSSQGTMDALANQLPFQVRSSTMPSVIRAHAIITLGKLCLQHEDLAKKSIPALVRELEVCEDVAVRNNVIIVMCDLCIRYTVMVDNYIPNISICLKDSDPFIRKQTLILLTNLLQEEYVKWKGCLFFRFVSTLVDPHPDIASLGEFCLAHLLLKRNPTMFFQHFIECIFHFNSYEKHGQYNKFSQTERGKRLFLLKGKTNKEKRMRIYKFLLEHFTDEQRFNVTSKICLSILACFTDGILPLDMEASELLSDTFDILSSKEIKLLAMRAQACKDLLEEDDMALANVVMQEAQMKIISQVQKRNFIENIIPIITSLKTVLEKNKIPALRELMNYLREVMQDYRDEIKDFFAVDKQLASELEYDMKKYNEQLAQEQALTAQADVSRMAEGGDRAQPMQGTPDSQAIPAAADQENVNVPVANSRPSAPGSSFTPTLSPISENGPLTMIPSARSMSLSTIAILNSVKKAVESKNKSHRRSLGALPFSVESGSPEKSRSHASLSMEQESDAAVKHVTKRAISTPEKSINNVTFGAGVSYIGTPATPLFTKEKVEAQDQGNDILCLSLPDKSPPQSPQWNVKSLARNKDNPRSSRRSLRKTPLKTAN", "length": 1491, "header": "tr|A0A9J7FXK2-1|A0A9J7FXK2_CRIGR Isoform 1 of Condensin-2 complex subunit D3 OS=Cricetulus griseus OX=10029 GN=Ncapd3 PE=4 SV=1 CANONICAL=A0A9J7FXK2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FT55-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK2/entry#A0A9J7FT55-1", "sequence": { "sequence": 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"length": 1351, "header": "tr|A0A9J7FT55-1|A0A9J7FXK2_CRIGR Computationally mapped isoform of Condensin-2 complex subunit D3 OS=Cricetulus griseus OX=10029 GN=Ncapd3 PE=4 SV=1 CANONICAL=A0A9J7FXK2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK2/entry#A0A9J7FXK2-1", "sequence": { "sequence": 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"length": 1491, "header": "tr|A0A9J7FXK2-1|A0A9J7FXK2_CRIGR Isoform 1 of Condensin-2 complex subunit D3 OS=Cricetulus griseus OX=10029 GN=Ncapd3 PE=4 SV=1 CANONICAL=A0A9J7FXK2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT55" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT55" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752080", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752080", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear lumen", "id": "GO:0031981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK2" } ], "pmid": "" }, { "name": "condensin complex", "id": "GO:0000796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000796", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXK2", "url": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVK2-1", "uniprot_ac": "A0A9J7FVK2", "uniprot_id": "A0A9J7FVK2_CRIGR", "mass": { "chemical_mass": 110227.0, "monoisotopic_mass": 110227.0 }, "refseq": { "ac": "XP_027267530", "name": "sorting nexin-19 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267530" }, "gene_names": [ { "name": "Snx19", "type": "recommended", "evidence": [ { "id": "A0A9J7FVK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2" } ] }, { "name": "Snx19", 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REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267530", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267530" } ] }, { "annotation": "Plays a role in intracellular vesicle trafficking and exocytosis. May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT65", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT65#function" }, { "database": "UniProtKB", "id": "ARBA00053440", "url": "https://www.uniprot.org/uniprotkb/ARBA00053440#function" }, { "database": "UniProtKB", "id": "A0A9J7FTK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK9#function" }, { "database": "UniProtKB", "id": "A0A9J7FVK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2#function" }, { "database": "UniProtKB", "id": "A0A9J7FXL2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL2#function" }, { "database": "UniProtKB", "id": "A0A9J7K7V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7V7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": 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"Protein" ] }, { "id": "A0A9J7FTK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXL2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7V7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAETVSPTQENAPESSGVFGNLWSSRKLMVVGVLLGSLLVIHLLVNMWLLILLCASLVVLGGWLGSNAIAGASGQLHLERFITVNACPPCPEAERQLEREINCTIQMIIRDFVLSWYRSVSQEPAFEAEMEAAMKGLVQELRRRISRVDSHALTQKVLTLCGCHLQSYIQAKEATAREQSYSGQPSQLWDAYCQATTPHPAMHSPTTEITYARGIVNLLFQELVPKPHLETRTGRHVVVELVTCNVILPLINKLSDPDWIHIILVSIFSKYRHDTAQGTKPPCSASVLEQSSVPTSLPLIVEVESLPIGKVPPSPVSAPVHITCSEPAPSPEVEEGHEAVEGDLTEMLEERKVGNNAPHFLQPDIRGPLFLCEDSELESPLSELGKETIMLMTPGNFLSDRIQDALCALEDSRTLEPKDGEGSEGMEGAEAEEAPGTDTDTGLLVSMLNCPEIQIDTADKDVEQEQVTPLTALPEEPENSCPPRPSCLEKDLTSGVSSLDPTLPPVPLSSSPPGPLSSATFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALNAENSSSLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNIKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKAGKSRLRFSSSKIAPALSIAEAQDRVLYSLQEGNSESEILSMFGMESFIEKQTKLLEMQPAEVPDKDPQQVPKECVDSCLLDTDIAQELKNSDPGTETELADTALDLILLLLMEQWTWLCTESMQKFLRLIFGTLVQRWLEVQVANLTCPQRWVQYLRLLRESIWPGGVLPKYPRPGRTQAQKAATEKQALQSLMSILPEFLVEILGVNKCQLSWSLVLESFQQPLINRHLIYCLGDIILEFLDLGASVEEPAPATSASDSPSSLKRMAVST", "length": 997, "header": "tr|A0A9J7FVK2-1|A0A9J7FVK2_CRIGR Isoform 1 of Sorting nexin-19 OS=Cricetulus griseus OX=10029 GN=Snx19 PE=3 SV=1 CANONICAL=A0A9J7FVK2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FT65-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2/entry#A0A9J7FT65-1", "sequence": { "sequence": "MKAETVSPTQENAPESSGVFGNLWSSRKLMVVGVLLGSLLVIHLLVNMWLLILLCASLVVLGGWLGSNAIAGASGQLHLERFITVNACPPCPEAERQLEREINCTIQMIIRDFVLSWYRSVSQEPAFEAEMEAAMKGLVQELRRRISRVDSHALTQKVLTLCGCHLQSYIQAKEATAREQSYSGQPSQLWDAYCQATTPHPAMHSPTTEITYARGIVNLLFQELVPKPHLETRTGRHVVVELVTCNVILPLINKLSDPDWIHIILVSIFSKYRHDTAQGTKPPCSASVLEQSSVPTSLPLIVEVESLPIGKVPPSPVSAPVHITCSEPAPSPEVEEGHEAVEGDLTEMLEERKVGNNAPHFLQPDIRGPLFLCEDSELESPLSELGKETIMLMTPGNFLSDRIQDALCALEDSRTLEPKDGEGSEGMEGAEAEEAPGTDTDTGLLVSMLNCPEIQIDTADKDVEQEQVTPLTALPEEPENSCPPRPSCLEKDLTSGVSSLDPTLPPVPLSSSPPGPLSSATFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALNAENSSSLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNIKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKAGKSRLRFSSSKIAPALSIAEAQDRVLYSLQEGNSESEILSMFGMESFIEKQTKLLEMQPAEVPDKDPQQVPKECVDSCLLDTDIAQELKNSDPGTETELADTALDLILLLLMEQWTWLCTESMQKFLRLIFGTLVQRYWSICFVQSFFCPVAIL", "length": 880, "header": "tr|A0A9J7FT65-1|A0A9J7FVK2_CRIGR Computationally mapped isoform of Sorting nexin-19 OS=Cricetulus griseus OX=10029 GN=Snx19 PE=3 SV=1 CANONICAL=A0A9J7FVK2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2/entry#A0A9J7FTK9-1", "sequence": { "sequence": "MKAETVSPTQENAPESSGVFGNLWSSRKLMVVGVLLGSLLVIHLLVNMWLLILLCASLVVLGGWLGSNAIAGASGQLHLERFITVNACPPCPEAERQLEREINCTIQMIIRDFVLSWYRSVSQEPAFEAEMEAAMKGLVQELRRRISRVDSHALTQKVLTLCGCHLQSYIQAKEATAREQSYSGQPSQLWDAYCQATTPHPAMHSPTTEITYARGIVNLLFQELVPKPHLETRTGRHVVVELVTCNVILPLINKLSDPDWIHIILVSIFSKYRHDTAQGTKPPCSASVLEQSSVPTSLPLIVEVESLPIGKVPPSPVSAPVHITCSEPAPSPEVEEGHEAVEGDLTEMLEERKVGNNAPHFLQPDIRGPLFLCEDSELESPLSELGKETIMLMTPGNFLSDRIQDALCALEDSRTLEPKDGEGSEGMEGAEAEEAPGTDTDTGLLVSMLNCPEIQIDTADKDVEQEQVTPLTALPEEPENSCPPRPSCLEKDLTSGVSSLDPTLPPVPLSSSPPGPLSSATFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALNAENSSSLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNIKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKAGKSRLRFSSSKIAPALSIAEAQDRVLYSLQEGNSESEILSMFGMESFIEKQTKLLEMQPAEVPDKDPQQVPKECVDSCLLDTDIAQELKNSDPGTETELADTALDLILLLLMEQWTWLCTESMQKFLRLIFGTLVQRDVERKPLTSVDWPRRDPSSLVYYIHCLPCIWEDITCPKFTLCLKTPCPILLHKNLHVMCL", "length": 923, "header": "tr|A0A9J7FTK9-1|A0A9J7FVK2_CRIGR Computationally mapped isoform of Sorting nexin-19 OS=Cricetulus griseus OX=10029 GN=Snx19 PE=3 SV=1 CANONICAL=A0A9J7FVK2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2/entry#A0A9J7FVK2-1", "sequence": { "sequence": "MKAETVSPTQENAPESSGVFGNLWSSRKLMVVGVLLGSLLVIHLLVNMWLLILLCASLVVLGGWLGSNAIAGASGQLHLERFITVNACPPCPEAERQLEREINCTIQMIIRDFVLSWYRSVSQEPAFEAEMEAAMKGLVQELRRRISRVDSHALTQKVLTLCGCHLQSYIQAKEATAREQSYSGQPSQLWDAYCQATTPHPAMHSPTTEITYARGIVNLLFQELVPKPHLETRTGRHVVVELVTCNVILPLINKLSDPDWIHIILVSIFSKYRHDTAQGTKPPCSASVLEQSSVPTSLPLIVEVESLPIGKVPPSPVSAPVHITCSEPAPSPEVEEGHEAVEGDLTEMLEERKVGNNAPHFLQPDIRGPLFLCEDSELESPLSELGKETIMLMTPGNFLSDRIQDALCALEDSRTLEPKDGEGSEGMEGAEAEEAPGTDTDTGLLVSMLNCPEIQIDTADKDVEQEQVTPLTALPEEPENSCPPRPSCLEKDLTSGVSSLDPTLPPVPLSSSPPGPLSSATFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALNAENSSSLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNIKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKAGKSRLRFSSSKIAPALSIAEAQDRVLYSLQEGNSESEILSMFGMESFIEKQTKLLEMQPAEVPDKDPQQVPKECVDSCLLDTDIAQELKNSDPGTETELADTALDLILLLLMEQWTWLCTESMQKFLRLIFGTLVQRWLEVQVANLTCPQRWVQYLRLLRESIWPGGVLPKYPRPGRTQAQKAATEKQALQSLMSILPEFLVEILGVNKCQLSWSLVLESFQQPLINRHLIYCLGDIILEFLDLGASVEEPAPATSASDSPSSLKRMAVST", "length": 997, "header": "tr|A0A9J7FVK2-1|A0A9J7FVK2_CRIGR Isoform 1 of Sorting nexin-19 OS=Cricetulus griseus OX=10029 GN=Snx19 PE=3 SV=1 CANONICAL=A0A9J7FVK2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2/entry#A0A9J7FXL2-1", "sequence": { "sequence": "MKAETVSPTQENAPESSGVFGNLWSSRKLMVVGVLLGSLLVIHLLVNMWLLILLCASLVVLGGWLGSNAIAGASGQLHLERFITVNACPPCPEAERQLEREINCTIQMIIRDFVLSWYRSVSQEPAFEAEMEAAMKGLVQELRRRISRVDSHALTQKVLTLCGCHLQSYIQAKEATAREQSYSGQPSQLWDAYCQATTPHPAMHSPTTEITYARGIVNLLFQELVPKPHLETRTGRHVVVELVTCNVILPLINKLSDPDWIHIILVSIFSKYRHDTAQGTKPPCSASVLEQSSVPTSLPLIVEVESLPIGKVPPSPVSAPVHITCSEPAPSPEVEEGHEAVEGDLTEMLEERKVGNNAPHFLQPDIRGPLFLCEDSELESPLSELGKETIMLMTPGNFLSDRIQDALCALEDSRTLEPKDGEGSEGMEGAEAEEAPGTDTDTGLLVSMLNCPEIQIDTADKDVEQEQVTPLTALPEEPENSCPPRPSCLEKDLTSGVSSLDPTLPPVPLSSSPPGPLSSATFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALNAENSSSLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNIKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAENESKPQTEGKKAGKSRLRFSSSKIAPALSIAEAQDRVLYSLQEGNSESEILSMFGMESFIEKQTKLLEMQPAEVPDKDPQQVPKECVDSCLLDTDIAQELKNSDPGTETELADTALDLILLLLMEQWTWLCTESMQKFLRLIFGTLVQSDGFAQIVLCLLGKKEYFLLCFFH", "length": 886, "header": "tr|A0A9J7FXL2-1|A0A9J7FXL2_CRIGR Computationally mapped isoform of Sorting nexin-19 OS=Cricetulus griseus OX=10029 GN=Snx19 PE=3 SV=1 CANONICAL=A0A9J7FVK2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K7V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2/entry#A0A9J7K7V7-1", "sequence": { "sequence": "MKAETVSPTQENAPESSGVFGNLWSSRKLMVVGVLLGSLLVIHLLVNMWLLILLCASLVVLGGWLGSNAIAGASGQLHLERFITVNACPPCPEAERQLEREINCTIQMIIRDFVLSWYRSVSQEPAFEAEMEAAMKGLVQELRRRISRVDSHALTQKVLTLCGCHLQSYIQAKEATAREQSYSGQPSQLWDAYCQATTPHPAMHSPTTEITYARGIVNLLFQELVPKPHLETRTGRHVVVELVTCNVILPLINKLSDPDWIHIILVSIFSKYRHDTAQGTKPPCSASVLEQSSVPTSLPLIVEVESLPIGKVPPSPVSAPVHITCSEPAPSPEVEEGHEAVEGDLTEMLEERKVGNNAPHFLQPDIRGPLFLCEDSELESPLSELGKETIMLMTPGNFLSDRIQDALCALEDSRTLEPKDGEGSEGMEGAEAEEAPGTDTDTGLLVSMLNCPEIQIDTADKDVEQEQVTPLTALPEEPENSCPPRPSCLEKDLTSGVSSLDPTLPPVPLSSSPPGPLSSATFSFEPLSSPDGPVVIQNLRITGTITAREHSGTGFHPYTLYTVKYETALNAENSSSLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNIKGPKKLFPDLPFGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKESEILSMFGMESFIEKQTKLLEMQPAEVPDKDPQQVPKECVDSCLLDTDIAQELKNSDPGTETELADTALDLILLLLMEQWTWLCTESMQKFLRLIFGTLVQRWLEVQVANLTCPQRWVQYLRLLRESIWPGGVLPKYPRPGRTQAQKAATEKQALQSLMSILPEFLVEILGVNKCQLSWSLVLESFQQPLINRHLIYCLGDIILEFLDLGASVEEPAPATSASDSPSSLKRMAVST", "length": 921, "header": "tr|A0A9J7K7V7-1|A0A9J7K7V7_CRIGR Computationally mapped isoform of Sorting nexin-19 OS=Cricetulus griseus OX=10029 GN=Snx19 PE=3 SV=1 CANONICAL=A0A9J7FVK2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT65", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT65" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FT65", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FT65" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754067", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754067", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "chondrocyte differentiation", "id": "GO:0002062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002062", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2" } ], "pmid": "" }, { "name": "insulin secretion", "id": "GO:0030073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030073", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2" } ], "pmid": "" }, { "name": "dense core granule maturation", "id": "GO:1990502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990502", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 715, "end_pos": 717, "annotation": "n_glycosylation_sequon" }, { "start_pos": 871, "end_pos": 873, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FVK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 539, "end_pos": 669, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FVK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK2" }, { "id": "PS51207", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51207" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PXA", "eco_id": "ECO_0000259", "start_pos": 95, "end_pos": 273, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 715, "end_pos": 717 }, { "start_pos": 871, "end_pos": 873 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FY26-1", "uniprot_ac": "A0A9J7FY26", "uniprot_id": "A0A9J7FY26_CRIGR", "mass": { "chemical_mass": 119894.0, "monoisotopic_mass": 119894.0 }, "refseq": { "ac": "XP_027267912", "name": "neural cell adhesion molecule 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267912" }, "gene_names": [ { "name": "Ncam1", "type": "recommended", "evidence": [ { "id": "A0A9J7FY26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26" } ] }, { "name": "Ncam1", "type": "synonym", "evidence": [ { "id": "XP_027267912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267912" } ] } ], "protein_names": [ { "name": "Neural cell adhesion molecule 1", "type": "recommended", "evidence": [ { "id": "A0A9J7FY26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#names_and_taxonomy" } ] }, { "name": "neural cell adhesion molecule 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027267912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267912" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267912" } ] }, { "annotation": "This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26#function" }, { "database": "UniProtKB", "id": "ARBA00003000", "url": "https://www.uniprot.org/uniprotkb/ARBA00003000#function" }, { "database": "UniProtKB", "id": "A0A9J7FTB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTB1#function" }, { "database": "UniProtKB", "id": "A0A9J7FTN3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTN3#function" }, { "database": "UniProtKB", "id": "A0A9J7FTN5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTN5#function" }, { "database": "UniProtKB", "id": "A0A9J7FV25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV25#function" }, { "database": "UniProtKB", "id": "A0A9J7JKH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH7#function" }, { "database": "UniProtKB", "id": "A0A8C2LNW8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNW8#function" }, { "database": "UniProtKB", "id": "A0A8C2LM83", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM83#function" }, { "database": "UniProtKB", "id": "A0A9J7JFY5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFY5#function" }, { "database": "UniProtKB", "id": "A0A9J7JN93", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN93#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ncam1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26", "locus": {} } ], "crossref": [ { "id": "A0A9J7FY26", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FY26", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05865", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05865", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05869", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05869", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770418", "url": "https://www.ncbi.nlm.nih.gov/gene/100770418", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770418", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770418", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEWKPEM", "url": "https://omabrowser.org/oma/group/SEWKPEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LNW8", "url": "https://www.orthodb.org/?gene=A0A8C2LNW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FV25", "url": "https://www.orthodb.org/?gene=A0A9J7FV25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FY26", "url": "https://www.orthodb.org/?gene=A0A9J7FY26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075:SF103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075:SF103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231:SF239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231:SF239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267912", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LM83", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LM83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LM83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LNW8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LNW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTN3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTN5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY26-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JFY5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JFY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JN93", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JN93-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRAKLASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPANGSPTPGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPELPADTTATVEDMLPSVTTVTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAVPDSNSVPTGQATPSKGSGVTAASSPPASAPKVAPLVDLSDTPTSTPSASNLSSTVLANQGAVLSPSTPVNAGEASKVPPASKQSPAPTSTPAGAASPLAAVAAPATEAPQAKQEAPSTKGPDPEPTQPGAMKNPPEAATAPASPKSKAASASTTNPSQGEDLKMDEGNFKTPDIDLAKDVFAALGSPAPATGASGQASELAPSTADSAVPPAPAKTEKGPVEAKSESQESEAKPAPTEVKTVPNDATQTKENESKA", "length": 1122, "header": "tr|A0A9J7FY26-1|A0A9J7FY26_CRIGR Isoform 1 of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LM83-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#A0A8C2LM83-1", "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVREPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRAKLASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPANGSPTPGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKSESQESEAKPAPTEVKTVPNDATQTKENESKA", "length": 849, "header": "tr|A0A8C2LM83-1|A0A8C2LM83_CRIGR Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LNW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#A0A8C2LNW8-1", "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVREPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPATLGGSSTSYTLVSLLFSVVTLLLLC", "length": 726, "header": "tr|A0A8C2LNW8-1|A0A8C2LNW8_CRIGR Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#A0A9J7FTB1-1", "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVREPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPANGSPTPGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKSESQESEAKPAPTEVKTVPNDATQTKENESKA", "length": 848, "header": "tr|A0A9J7FTB1-1|A0A9J7FY26_CRIGR Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#A0A9J7FTN3-1", "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPANGSPTPGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPELPADTTATVEDMLPSVTTVTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAVPDSNSVPTGQATPSKGSGVTAASSPPASAPKVAPLVDLSDTPTSTPSASNLSSTVLANQGAVLSPSTPVNAGEASKVPPASKQSPAPTSTPAGAASPLAAVAAPATEAPQAKQEAPSTKGPDPEPTQPGAMKNPPEAATAPASPKSKAASASTTNPSQGEDLKMDEGNFKTPDIDLAKDVFAALGSPAPATGASGQASELAPSTADSAVPPAPAKTEKGPVEAKSESQESEAKPAPTEVKTVPNDATQTKENESKA", "length": 1121, "header": "tr|A0A9J7FTN3-1|A0A9J7FY26_CRIGR Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#A0A9J7FTN5-1", "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVREPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPANGSPTPGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPELPADTTATVEDMLPSVTTVTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAVPDSNSVPTGQATPSKGSGVTAASSPPASAPKVAPLVDLSDTPTSTPSASNLSSTVLANQGAVLSPSTPVNAGEASKVPPASKQSPAPTSTPAGAASPLAAVAAPATEAPQAKQEAPSTKGPDPEPTQPGAMKNPPEAATAPASPKSKAASASTTNPSQGEDLKMDEGNFKTPDIDLAKDVFAALGSPAPATGASGQASELAPSTADSAVPPAPAKTEKGPVEAKSESQESEAKPAPTEVKTVPNDATQTKENESKA", "length": 1120, "header": "tr|A0A9J7FTN5-1|A0A9J7FY26_CRIGR Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FV25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#A0A9J7FV25-1", "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPATLGGSSTSYTLVSLLFSVVTLLLLC", "length": 727, "header": "tr|A0A9J7FV25-1|A0A9J7FV25_CRIGR Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FY26-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#A0A9J7FY26-1", "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRAKLASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPANGSPTPGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPELPADTTATVEDMLPSVTTVTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAVPDSNSVPTGQATPSKGSGVTAASSPPASAPKVAPLVDLSDTPTSTPSASNLSSTVLANQGAVLSPSTPVNAGEASKVPPASKQSPAPTSTPAGAASPLAAVAAPATEAPQAKQEAPSTKGPDPEPTQPGAMKNPPEAATAPASPKSKAASASTTNPSQGEDLKMDEGNFKTPDIDLAKDVFAALGSPAPATGASGQASELAPSTADSAVPPAPAKTEKGPVEAKSESQESEAKPAPTEVKTVPNDATQTKENESKA", "length": 1122, "header": "tr|A0A9J7FY26-1|A0A9J7FY26_CRIGR Isoform 1 of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JFY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#A0A9J7JFY5-1", "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRAKLASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPANGSPTPGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKSESQESEAKPAPTEVKTVPNDATQTKENESKA", "length": 850, "header": "tr|A0A9J7JFY5-1|A0A9J7JFY5_CRIGR Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#A0A9J7JKH7-1", "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVREPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRAKLASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPANGSPTPGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPELPADTTATVEDMLPSVTTVTTNSDTITETFATAQNSPTSETTTLTSSIAPPATAVPDSNSVPTGQATPSKGSGVTAASSPPASAPKVAPLVDLSDTPTSTPSASNLSSTVLANQGAVLSPSTPVNAGEASKVPPASKQSPAPTSTPAGAASPLAAVAAPATEAPQAKQEAPSTKGPDPEPTQPGAMKNPPEAATAPASPKSKAASASTTNPSQGEDLKMDEGNFKTPDIDLAKDVFAALGSPAPATGASGQASELAPSTADSAVPPAPAKTEKGPVEAKSESQESEAKPAPTEVKTVPNDATQTKENESKA", "length": 1121, "header": "tr|A0A9J7JKH7-1|A0A9J7JKH7_CRIGR Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JN93-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26/entry#A0A9J7JN93-1", "sequence": { "sequence": "MLRTTDLIWTLFFLGTAVALQVDIVPSQGEISVGESKFFLCQVAGEAKDKDISWFSPNGEKLSPNQQRISVVWNDDDSSTLTIYNANIDDAGIYKCVVTGEDGTQSEATVNVKIFQKLMFKNAPTPQEFKEGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMSWTKDGEPIEIEEEDDEKHVFSDDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDEPEATGGVPILKYKAEWKSLSEEAWHFKWYDAKEANMEGIVTIMGLKPETRYTVRLAALNGKGLGEISAATEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRALASEWKPEIRLPSGSDHVMLKSLDWNAEYEVSVVAENQQGKSKAAHFVFKTLAQPTAIPANGSPTPGLSTGAIVGILIVIFVLLLVVMDITCYFLNKCGLLMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKSESQESEAKPAPTEVKTVPNDATQTKENESKA", "length": 849, "header": "tr|A0A9J7JN93-1|A0A9J7JN93_CRIGR Computationally mapped isoform of Neural cell adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=Ncam1 PE=4 SV=1 CANONICAL=A0A9J7FY26-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 708, "start_aa": "Thr", "end_pos": 708, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr708", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 878, "start_aa": "Thr", "end_pos": 878, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr878", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 911, "start_aa": "Thr", "end_pos": 911, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr911", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 956, "start_aa": "Thr", "end_pos": 956, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr956", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTB1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTB1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770418", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770418", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P13591-2", "protein_name": "Neural cell adhesion molecule 1", "gene_name": "NCAM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTSGLSTGAIVGILIVIFVLLLVVVDITCYFLNKCGLFMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKPECQETETKPAPAEVKTVPNDATQTKENESKA", "length": 858 }, "evidence": [ { "id": "A0A9J7FY26", "url": "https://omabrowser.org/oma/group/A0A9J7FY26/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13595-1", "protein_name": "Neural cell adhesion molecule 1", "gene_name": "Ncam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070593", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26" } ], "pmid": "" }, { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY26", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1118, "end_pos": 1120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVH3-1", "uniprot_ac": "A0A9J7FVH3", "uniprot_id": "A0A9J7FVH3_CRIGR", "mass": { "chemical_mass": 86243.0, "monoisotopic_mass": 86243.0 }, "refseq": { "ac": "XP_027268256", "name": "discoidin, CUB and LCCL domain-containing protein 2 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268256" }, "gene_names": [ { "name": "Dcbld2", "type": "recommended", "evidence": [ { "id": "A0A9J7FVH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3" } ] }, { "name": "Dcbld2", "type": "synonym", "evidence": [ { "id": "XP_027268256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268256" } ] } ], "protein_names": [ { "name": "Discoidin, CUB and LCCL domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A9J7FVH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3/entry#names_and_taxonomy" } ] }, { "name": "Endothelial and smooth muscle cell-derived neuropilin-like protein", "type": "synonym", "evidence": [ { "id": "A0A9J7FVH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3/entry#names_and_taxonomy" } ] }, { "name": "discoidin, CUB and LCCL domain-containing protein 2 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027268256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268256" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268256" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dcbld2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVH3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVH3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00057", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00057", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772480", "url": "https://www.ncbi.nlm.nih.gov/gene/100772480", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050633", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050633", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772480", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772480", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVH3", "url": "https://www.orthodb.org/?gene=A0A9J7FVH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46806", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46806", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46806:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46806:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268256", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FTD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXN7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K8S4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K8S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8S4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRAPLRAAHSPQGPRGQAAPAATGRAALPSAGCCPLPPGRNSSSRPRLLLLLLLLLQDAGAQQGDGCGHTVLGPESGTLTSINYPHTYPNSTVCEWEIRVKMGERIRIKFGDFDIEDSDSCHFNYLKIYNGIGVSRTEIGKYCGLGLQMNRSIESKGSEITVLFMSGTHASGRGFLASYSVIDKQDLITCLDNITKFWEPEFSKYCPAGCLLPFAEVSGTIPHGYRDSSPLCMAGIHAGVVSNVLGGQISVVISKGTPYYESSLANNVTSMVGYLSPSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHMGQENSWKPEKARLRKPGPPWAAFATDEHQWLQIDLNKEKKITGIVTTGSTMVEHNYYVSAYRVLYSDDGQRWTVYREPGMEQDKIFQGNKDYHKDVRNNFLPPIIARFIRVNPVQWQQKIAMKVELLGCQFTLKGRLPKLTQPPPPRNSNNLKNTTAPPKLGRVPKFNQALQPRSRNELPAQTAQTTATPDIKNTTVTPNVTKDVALAAVLVPVLVMALTTLILILVCAWHWRNRKKKTEGTYDLPHWDRAELVSVSNTWSLAYNHNEGWWKGVKQFLPAKSLEHEETPVRYSNSEVSHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPVQEVYHAYAEPLPITGPEYATPIVMDMSGHPTASIGLPSTSTFKSAGNQPPPALVGTYNTLLSRTDSCSSSGRAQYDTPKGGKPAAAPEELVYQVPQSTQEVAGAGGDEKCDVFKEIL", "length": 788, "header": "tr|A0A9J7FVH3-1|A0A9J7FVH3_CRIGR Isoform 1 of Discoidin, CUB and LCCL domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Dcbld2 PE=4 SV=1 CANONICAL=A0A9J7FVH3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FTD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3/entry#A0A9J7FTD2-1", "sequence": { "sequence": "MASRAPLRAAHSPQGPRGQAAPAATGRAALPSAGCCPLPPGRNSSSRPRLLLLLLLLLQDAGAQQGDGCGHTVLGPESGTLTSINYPHTYPNSTVCEWEIRVKMGERIRIKFGDFDIEDSDSCHFNYLKIYNGIGVSRTEIGKYCGLGLQMNRSIESKGSEITVLFMSGTHASGRGFLASYSVIDKQDLITCLDNITKFWEPEFSKYCPAGCLLPFAEVSGTIPHGYRDSSPLCMAGIHAGVVSNVLGGQISVVISKGTPYYESSLANNVTSMVGYLSPSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHMGQENSWKPEKARLRKPGPPWAAFATDEHQWLQIDLNKEKKITGIVTTGSTMVEHNYYVSAYRVLYSDDGQRWTVYREPGMEQDKIFQGNKDYHKDVRNNFLPPIIARFIRVNPVQWQQKIAMKVELLGCQFTLKGRLPKLTQPPPPRNSNNLKNTTAPPKLGRVPKFNQALQPRSRNELPAQTAQTTATPDIKNTTVTPNVTKDVALAAVLVPVLVMALTTLILILVCAWHWRNRKKKTEGTYDLPHWDRAGWWKGVKQFLPAKSLEHEETPVRYSNSEVSHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPVQEVYHAYAEPLPITGPEYATPIVMDMSGHPTASIGLPSTSTFKSAGNQPPPALVGTYNTLLSRTDSCSSSGRAQYDTPKGGKPAAAPEELVYQVPQSTQEVAGAGGDEKCDVFKEIL", "length": 771, "header": "tr|A0A9J7FTD2-1|A0A9J7FVH3_CRIGR Computationally mapped isoform of Discoidin, CUB and LCCL domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Dcbld2 PE=4 SV=1 CANONICAL=A0A9J7FVH3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3/entry#A0A9J7FVH3-1", "sequence": { "sequence": "MASRAPLRAAHSPQGPRGQAAPAATGRAALPSAGCCPLPPGRNSSSRPRLLLLLLLLLQDAGAQQGDGCGHTVLGPESGTLTSINYPHTYPNSTVCEWEIRVKMGERIRIKFGDFDIEDSDSCHFNYLKIYNGIGVSRTEIGKYCGLGLQMNRSIESKGSEITVLFMSGTHASGRGFLASYSVIDKQDLITCLDNITKFWEPEFSKYCPAGCLLPFAEVSGTIPHGYRDSSPLCMAGIHAGVVSNVLGGQISVVISKGTPYYESSLANNVTSMVGYLSPSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHMGQENSWKPEKARLRKPGPPWAAFATDEHQWLQIDLNKEKKITGIVTTGSTMVEHNYYVSAYRVLYSDDGQRWTVYREPGMEQDKIFQGNKDYHKDVRNNFLPPIIARFIRVNPVQWQQKIAMKVELLGCQFTLKGRLPKLTQPPPPRNSNNLKNTTAPPKLGRVPKFNQALQPRSRNELPAQTAQTTATPDIKNTTVTPNVTKDVALAAVLVPVLVMALTTLILILVCAWHWRNRKKKTEGTYDLPHWDRAELVSVSNTWSLAYNHNEGWWKGVKQFLPAKSLEHEETPVRYSNSEVSHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPVQEVYHAYAEPLPITGPEYATPIVMDMSGHPTASIGLPSTSTFKSAGNQPPPALVGTYNTLLSRTDSCSSSGRAQYDTPKGGKPAAAPEELVYQVPQSTQEVAGAGGDEKCDVFKEIL", "length": 788, "header": "tr|A0A9J7FVH3-1|A0A9J7FVH3_CRIGR Isoform 1 of Discoidin, CUB and LCCL domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Dcbld2 PE=4 SV=1 CANONICAL=A0A9J7FVH3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3/entry#A0A9J7FXN7-1", "sequence": { "sequence": "MGERIRIKFGDFDIEDSDSCHFNYLKIYNGIGVSRTEIGKYCGLGLQMNRSIESKGSEITVLFMSGTHASGRGFLASYSVIDKQDLITCLDNITKFWEPEFSKYCPAGCLLPFAEVSGTIPHGYRDSSPLCMAGIHAGVVSNVLGGQISVVISKGTPYYESSLANNVTSMVGYLSPSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHMGQENSWKPEKARLRKPGPPWAAFATDEHQWLQIDLNKEKKITGIVTTGSTMVEHNYYVSAYRVLYSDDGQRWTVYREPGMEQDKIFQGNKDYHKDVRNNFLPPIIARFIRVNPVQWQQKIAMKVELLGCQFTLKGRLPKLTQPPPPRNSNNLKNTTAPPKLGRVPKFNQALQPRSRNELPAQTAQTTATPDIKNTTVTPNVTKDVALAAVLVPVLVMALTTLILILVCAWHWRNRKKKTEGTYDLPHWDRAELVSVSNTWSLAYNHNEGWWKGVKQFLPAKSLEHEETPVRYSNSEVSHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPVQEVYHAYAEPLPITGPEYATPIVMDMSGHPTASIGLPSTSTFKSAGNQPPPALVGTYNTLLSRTDSCSSSGRAQYDTPKGGKPAAAPEELVYQVPQSTQEVAGAGGDEKCDVFKEIL", "length": 685, "header": "tr|A0A9J7FXN7-1|A0A9J7FXN7_CRIGR Computationally mapped isoform of Discoidin, CUB and LCCL domain-containing protein 2 isoform X7 OS=Cricetulus griseus OX=10029 GN=Dcbld2 PE=4 SV=1 CANONICAL=A0A9J7FVH3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K8S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3/entry#A0A9J7K8S4-1", "sequence": { "sequence": "MASRAPLRAAHSPQGPRGQAAPAATGRAALPSAGCCPLPPGRNSSSRPRLLLLLLLLLQDAGAQQGDGCGHTVLGPESGTLTSINYPHTYPNSTVCEWEIRVKMGERIRIKFGDFDIEDSDSCHFNYLKIYNGIGVSRTEIDLITCLDNITKFWEPEFSKYCPAGCLLPFAEVSGTIPHGYRDSSPLCMAGIHAGVVSNVLGGQISVVISKGTPYYESSLANNVTSMVGYLSPSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHMGQENSWKPEKARLRKPGPPWAAFATDEHQWLQIDLNKEKKITGIVTTGSTMVEHNYYVSAYRVLYSDDGQRWTVYREPGMEQDKIFQGNKDYHKDVRNNFLPPIIARFIRVNPVQWQQKIAMKVELLGCQFTLKGRLPKLTQPPPPRNSNNLKNTTAPPKLGRVPKFNQALQPRSRNELPAQTAQTTATPDIKNTTVTPNVTKDVALAAVLVPVLVMALTTLILILVCAWHWRNRKKKTEGTYDLPHWDRAELVSVSNTWSLAYNHNEGWWKGVKQFLPAKSLEHEETPVRYSNSEVSHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPVQEVYHAYAEPLPITGPEYATPIVMDMSGHPTASIGLPSTSTFKSAGNQPPPALVGTYNTLLSRTDSCSSSGRAQYDTPKGGKPAAAPEELVYQVPQSTQEVAGAGGDEKCDVFKEIL", "length": 742, "header": "tr|A0A9J7K8S4-1|A0A9J7K8S4_CRIGR Computationally mapped isoform of Discoidin, CUB and LCCL domain-containing protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Dcbld2 PE=4 SV=1 CANONICAL=A0A9J7FVH3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTD2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FTD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTD2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772480", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772480", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "wound healing", "id": "GO:0042060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042060", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FVH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 184, "start_aa": "Cys", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FVH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3" }, { "id": "PS50022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F5/8 type C", "eco_id": "ECO_0000259", "start_pos": 289, "end_pos": 446, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FVH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH3" }, { "id": "PS50820", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50820" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LCCL", "eco_id": "ECO_0000259", "start_pos": 179, "end_pos": 282, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 471, "end_pos": 473 }, { "start_pos": 511, "end_pos": 513 }, { "start_pos": 517, "end_pos": 519 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FWF8-1", "uniprot_ac": "A0A9J7FWF8", "uniprot_id": "A0A9J7FWF8_CRIGR", "mass": { "chemical_mass": 39403.0, "monoisotopic_mass": 39403.0 }, "refseq": { "ac": "XP_027268339", "name": "leukocyte surface antigen CD47 isoform X9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268339" }, "gene_names": [ { "name": "Cd47", "type": "recommended", "evidence": [ { "id": "A0A9J7FWF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" } ] }, { "name": "Cd47", "type": "synonym", "evidence": [ { "id": "XP_027268339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268339" } ] } ], "protein_names": [ { "name": "Leukocyte surface antigen CD47", "type": "recommended", "evidence": [ { "id": "A0A9J7FWF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#names_and_taxonomy" } ] }, { "name": "Integrin-associated protein", "type": "synonym", "evidence": [ { "id": "A0A9J7FWF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#names_and_taxonomy" } ] }, { "name": "leukocyte surface antigen CD47 isoform X9", "type": "synonym", "evidence": [ { "id": "XP_027268339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268339" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268339" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cd47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8", "locus": {} } ], "crossref": [ { "id": "A0A9J7FWF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FWF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16090", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16090", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770433", "url": "https://www.ncbi.nlm.nih.gov/gene/100770433", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037805", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037805", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770433", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770433", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FWF8", "url": "https://www.orthodb.org/?gene=A0A9J7FWF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10613", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10613", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10613:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10613:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04549", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04549", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FU99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FU99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYQ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JG88", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JG88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JG88-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JG88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMR8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWPLVAALLLGSCCCGSAQLLFSNVKSVEFTKCNETVVIPCIVLNVEAQSTEEMYVKWKLNKTYIFIYDGSKNNSTVETNFTSAKISVSDLLKGDASLKMERQQAVLGNYTCEVTELSREGKTVIELKYRMDSIPDQGSDCSYHTTPTPAGDEKEKGGCKLASWFSPNEKILIVIFPILAILLFWGKFGILTLKYKSTRTNKRIILLLVAGLVLTVIVVVGAILLIPGENPVKSASGLGLIVISIGTLILLQYNVFMTAFGMTSFTIAILITQVLGYVLALVGLCLCIMACEPVHGPLLISGLGIIALAELLGLVYMKFVGHLKSLVYVAQELFPKPLPSSAIYEQLPTRGLYNLLGISEGK", "length": 362, "header": "tr|A0A9J7FWF8-1|A0A9J7FWF8_CRIGR Isoform 1 of Leukocyte surface antigen CD47 OS=Cricetulus griseus OX=10029 GN=Cd47 PE=4 SV=1 CANONICAL=A0A9J7FWF8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FU99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#A0A9J7FU99-1", "sequence": { "sequence": "MWPLVAALLLGSCCCGSAQLLFSNVKSVEFTKCNETVVIPCIVLNVEAQSTEEMYVKWKLNKTYIFIYDGSKNNSTVETNFTSAKISVSDLLKGDASLKMERQQAVLGNYTCEVTELSREGKTVIELKYRMDSIPDQGSDCSYHTTPTPAGDEKEKGGCKLASWFSPNEKILIVIFPILAILLFWGKFGILTLKYKSTRTNKRIILLLVAGLVLTVIVVVGAILLIPGENPVKSASGLGLIVISIGTLILLQYNVFMTAFGMTSFTIAILITQVLGYVLALVGLCLCIMACEPVHGPLLISGLGIIALAELLGLVYMKFVASNQRTIQPPRKAVEEPLNE", "length": 340, "header": "tr|A0A9J7FU99-1|A0A9J7FWF8_CRIGR Computationally mapped isoform of Leukocyte surface antigen CD47 OS=Cricetulus griseus OX=10029 GN=Cd47 PE=4 SV=1 CANONICAL=A0A9J7FWF8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FUC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#A0A9J7FUC1-1", "sequence": { "sequence": "MWPLVAALLLGSCCCGSAQLLFSNVKSVEFTKCNETVVIPCIVLNVEAQSTEEMYVKWKLNKTYIFIYDGSKNNSTVETNFTSAKISVSDLLKGDASLKMERQQAVLGNYTCEVTELSREGKTVIELKYRMASWFSPNEKILIVIFPILAILLFWGKFGILTLKYKSTRTNKRIILLLVAGLVLTVIVVVGAILLIPGENPVKSASGLGLIVISIGTLILLQYNVFMTAFGMTSFTIAILITQVLGYVLALVGLCLCIMACEPVHGPLLISGLGIIALAELLGLVYMKFVGHLKSLVYVAQELFPKPLPSSAIYEQLPTRGLYNLLGISEGK", "length": 332, "header": "tr|A0A9J7FUC1-1|A0A9J7FWF8_CRIGR Computationally mapped isoform of Leukocyte surface antigen CD47 OS=Cricetulus griseus OX=10029 GN=Cd47 PE=4 SV=1 CANONICAL=A0A9J7FWF8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FUN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#A0A9J7FUN6-1", "sequence": { "sequence": "MWPLVAALLLGSCCCGSAQLLFSNVKSVEFTKCNETVVIPCIVLNVEAQSTEEMYVKWKLNKTYIFIYDGSKNNSTVETNFTSAKISVSDLLKGDASLKMERQQAVLGNYTCEVTELSREGKTVIELKYRMDSIPDQGSDCSYHTTPTPAGDEKEKGGCKLASWFSPNEKILIVIFPILAILLFWGKFGILTLKYKSTRTNKRIILLLVAGLVLTVIVVVGAILLIPGENPVKSASGLGLIVISIGTLILLQYNVFMTAFGMTSFTIAILITQVLGYVLALVGLCLCIMACEPVHGPLLISGLGIIALAELLGLVYMKFVGHLKSLVYVAQELFPKPLPSSAIYEQLPTRGLYNLLGKL", "length": 359, "header": "tr|A0A9J7FUN6-1|A0A9J7FWF8_CRIGR Computationally mapped isoform of Leukocyte surface antigen CD47 OS=Cricetulus griseus OX=10029 GN=Cd47 PE=4 SV=1 CANONICAL=A0A9J7FWF8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#A0A9J7FWF8-1", "sequence": { "sequence": "MWPLVAALLLGSCCCGSAQLLFSNVKSVEFTKCNETVVIPCIVLNVEAQSTEEMYVKWKLNKTYIFIYDGSKNNSTVETNFTSAKISVSDLLKGDASLKMERQQAVLGNYTCEVTELSREGKTVIELKYRMDSIPDQGSDCSYHTTPTPAGDEKEKGGCKLASWFSPNEKILIVIFPILAILLFWGKFGILTLKYKSTRTNKRIILLLVAGLVLTVIVVVGAILLIPGENPVKSASGLGLIVISIGTLILLQYNVFMTAFGMTSFTIAILITQVLGYVLALVGLCLCIMACEPVHGPLLISGLGIIALAELLGLVYMKFVGHLKSLVYVAQELFPKPLPSSAIYEQLPTRGLYNLLGISEGK", "length": 362, "header": "tr|A0A9J7FWF8-1|A0A9J7FWF8_CRIGR Isoform 1 of Leukocyte surface antigen CD47 OS=Cricetulus griseus OX=10029 GN=Cd47 PE=4 SV=1 CANONICAL=A0A9J7FWF8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#A0A9J7FYQ4-1", "sequence": { "sequence": "MWPLVAALLLGSCCCGSAQLLFSNVKSVEFTKCNETVVIPCIVLNVEAQSTEEMYVKWKLNKTYIFIYDGSKNNSTVETNFTSAKISVSDLLKGDASLKMERQQAVLGNYTCEVTELSREGKTVIELKYRMDSIPDQGSDCSYHTTPTPAGDEKEKGGCKLASWFSPNEKILIVIFPILAILLFWGKFGILTLKYKSTRTNKRIILLLVAGLVLTVIVVVGAILLIPGENPVKSASGLGLIVISIGTLILLQYNVFMTAFGMTSFTIAILITQVLGYVLALVGLCLCIMACEPVHGPLLISGLGIIALAELLGLVYMKFVASNQRTIQPPRKAVEEPLNAFKESKGMMNDE", "length": 351, "header": "tr|A0A9J7FYQ4-1|A0A9J7FYQ4_CRIGR Computationally mapped isoform of Leukocyte surface antigen CD47 OS=Cricetulus griseus OX=10029 GN=Cd47 PE=4 SV=1 CANONICAL=A0A9J7FWF8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JG88-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#A0A9J7JG88-1", "sequence": { "sequence": "MWPLVAALLLGSCCCGSAQLLFSNVKSVEFTKCNETVVIPCIVLNVEAQSTEEMYVKWKLNKTYIFIYDGSKNNSTVETNFTSAKISVSDLLKGDASLKMERQQAVLGNYTCEVTELSREGKTVIELKYRMASWFSPNEKILIVIFPILAILLFWGKFGILTLKYKSTRTNKRIILLLVAGLVLTVIVVVGAILLIPGENPVKSASGLGLIVISIGTLILLQYNVFMTAFGMTSFTIAILITQVLGYVLALVGLCLCIMACEPVHGPLLISGLGIIALAELLGLVYMKFVASNQRTIQPPRKAVEEPLNAFKESKGMMNDE", "length": 321, "header": "tr|A0A9J7JG88-1|A0A9J7JG88_CRIGR Computationally mapped isoform of Leukocyte surface antigen CD47 OS=Cricetulus griseus OX=10029 GN=Cd47 PE=4 SV=1 CANONICAL=A0A9J7FWF8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#A0A9J7JKU1-1", "sequence": { "sequence": "MWPLVAALLLGSCCCGSAQLLFSNVKSVEFTKCNETVVIPCIVLNVEAQSTEEMYVKWKLNKTYIFIYDGSKNNSTVETNFTSAKISVSDLLKGDASLKMERQQAVLGNYTCEVTELSREGKTVIELKYRMDSIPDQGSDCSYHTTPTPAGDEKEKGGCKLASWFSPNEKILIVIFPILAILLFWGKFGILTLKYKSTRTNKRIILLLVAGLVLTVIVVVGAILLIPGENPVKSASGLGLIVISIGTLILLQYNVFMTAFGMTSFTIAILITQVLGYVLALVGLCLCIMACEPVHGPLLISGLGIIALAELLGLVYMKFVASNQRTIQPPRNK", "length": 333, "header": "tr|A0A9J7JKU1-1|A0A9J7JKU1_CRIGR Computationally mapped isoform of Leukocyte surface antigen CD47 OS=Cricetulus griseus OX=10029 GN=Cd47 PE=4 SV=1 CANONICAL=A0A9J7FWF8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JMR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#A0A9J7JMR8-1", "sequence": { "sequence": "MYVKWKLNKTYIFIYDGSKNNSTVETNFTSAKISVSDLLKGDASLKMERQQAVLGNYTCEVTELSREGKTVIELKYRMDSIPDQGSDCSYHTTPTPAGDEKEKGGCKLASWFSPNEKILIVIFPILAILLFWGKFGILTLKYKSTRTNKRIILLLVAGLVLTVIVVVGAILLIPGENPVKSASGLGLIVISIGTLILLQYNVFMTAFGMTSFTIAILITQVLGYVLALVGLCLCIMACEPVHGPLLISGLGIIALAELLGLVYMKFVGHLKSLVYVAQELFPKPLPSSAIYEQLPTRGLYNLLGISEGK", "length": 309, "header": "tr|A0A9J7JMR8-1|A0A9J7JMR8_CRIGR Computationally mapped isoform of Leukocyte surface antigen CD47 isoform X17 OS=Cricetulus griseus OX=10029 GN=Cd47 PE=4 SV=1 CANONICAL=A0A9J7FWF8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8/entry#A0A9J7JNL6-1", "sequence": { "sequence": "MWPLVAALLLGSCCCGSAQLLFSNVKSVEFTKCNETVVIPCIVLNVEAQSTEEMYVKWKLNKTYIFIYDGSKNNSTVETNFTSAKISVSDLLKGDASLKMERQQAVLGNYTCEVTELSREGKTVIELKYRMDSIPDQGSDCSYHTTPTPAGDEKEKGGCKLASWFSPNEKILIVIFPILAILLFWGKFGILTLKYKSTRTNKRIILLLVAGLVLTVIVVVGAILLIPGENPVKSASGLGLIVISIGTLILLQYNVFMTAFGMTSFTIAILITQVLGYVLALVGLCLCIMACEPVHGPLLISGLGIIALAELLGLVYMKFVE", "length": 321, "header": "tr|A0A9J7JNL6-1|A0A9J7JNL6_CRIGR Computationally mapped isoform of Leukocyte surface antigen CD47 OS=Cricetulus griseus OX=10029 GN=Cd47 PE=4 SV=1 CANONICAL=A0A9J7FWF8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 148, "start_aa": "Thr", "end_pos": 148, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr148", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU99" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FU99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU99" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770433", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770433", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of cell-cell adhesion", "id": "GO:0022409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022409", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" } ], "pmid": "" }, { "name": "positive regulation of inflammatory response", "id": "GO:0050729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050729", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" } ], "pmid": "" }, { "name": "positive regulation of phagocytosis", "id": "GO:0050766", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050766", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" } ], "pmid": "" }, { "name": "positive regulation of immune system process", "id": "GO:0002684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002684", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "thrombospondin receptor activity", "id": "GO:0070053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070053", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FWF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWF8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 125, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 148 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 74, "end_pos": 76 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FV09-1", "uniprot_ac": "A0A9J7FV09", "uniprot_id": "A0A9J7FV09_CRIGR", "mass": { "chemical_mass": 109034.0, "monoisotopic_mass": 109034.0 }, "refseq": { "ac": "XP_027268626", "name": "run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268626" }, "gene_names": [ { "name": "Rubcn", "type": "recommended", "evidence": [ { "id": "A0A9J7FV09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09" } ] }, { "name": "Rubcn", "type": "synonym", "evidence": [ { "id": "XP_027268626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268626" } ] } ], "protein_names": [ { "name": "Run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7FV09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09/entry#names_and_taxonomy" } ] }, { "name": "run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027268626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268626" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268626" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rubcn", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09", "locus": {} } ], "crossref": [ { "id": "A0A9J7FV09", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FV09", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17686", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17686", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754353", "url": "https://www.ncbi.nlm.nih.gov/gene/100754353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754353", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LHD1", "url": "https://www.orthodb.org/?gene=A0A8C2LHD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FV09", "url": "https://www.orthodb.org/?gene=A0A9J7FV09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45971", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45971", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45971:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45971:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21054", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21054", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268626", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LHD1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LHD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV09-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPEGAGMDLGGGRERLPEESRREHWQLLGNLKTTVEGLVSANCPNVWSKYGGLERLCRDMQNILYHGLIHDQVCCRQADYWQFVKDIRWLSPHSALHVEKFINLHENGQSSADVSNRAVAELWLQHSLQSHCLSAQLRPLLGDRQYIRKFYTETAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPGSTYTPPASCAQQTYFGSSSNLHQSMPHHSSERRSTSFSLSGPPWKPQEDRDLSPAESQTAQAPLLSDPALAQDSPLTPHEMSSSTLTSPIEASWVSSQNDSPSDASEGPEYLAIGNPDPHGRTASCQSHSSNAESSSSHLFSSSSPQKPDSAASSLGDQEAGRQSQPGSVLRRSSFSEGQTVLVASGTKKSHIRSHSDTNIASKGATEGAQDLCSGESMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPAYQETEHGSFRVTSSSSQFSSRDSTQFSDSGSADDVDEFEIQDGSEGSNLTHMSKSGLSVSVASMFSDADIRRSTVSNGKSSISQNFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPGKALSSPMPVGGDLRGDYIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYSISNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFDVVPGHLTEDLHLYSLNDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEDDVIFPFELHKCRTCEECKACYHKVCFKSGRCPRCERLQARRELLAKQSLESYLSDYEEEPTEALALEATVLETT", "length": 978, "header": "tr|A0A9J7FV09-1|A0A9J7FV09_CRIGR Isoform 1 of Run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Rubcn PE=4 SV=1 CANONICAL=A0A9J7FV09-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LHD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09/entry#A0A8C2LHD1-1", "sequence": { "sequence": "MRPEGAGMDLGGGRERLPEESRREHWQLLGNLKTTVEGLVSANCPNVWSKYGGLERLCRDMQNILYHGLIHDQVCCRQADYWQFVKDIRWLSPHSALHVEKFINLHENGQSSADVSNRAVAELWLQHSLQSHCLSAQLRPLLGDRQYIRKFYTETAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPGSTYTPPASCAQQTYFGSSSNLHQSMPHHSSERRSTSFSLSGPPWKPQEDRDLSPAESQTAQAPLLSDPALAQDSPLTPHEMSSSTLTSPIEASWVSSQNDSPSDASEGPEYLAIGNPDPHGRTASCQSHSSNAESSSSHLFSSSSPQKPDSAASSLGDQEAGRQSQPGSVLRRSSFSEGQTVLVASGTKKSHIRSHSDTNIASKGATEGAQDLCSGESMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPAYQETEHGSFRVTSSSSQFSSRDSTQFSDSGSADDVDEFEIQDADIRRSTVSNGKSSISQNFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYSISNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFDVVPGHLTEDLHLYSLNDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEDDVIFPFELHKCRTCEECKACYHKVCFKSGRCPRCERLQARRELLAKQSLESYLSDYEEEPTEALALEATVLETT", "length": 937, "header": "tr|A0A8C2LHD1-1|A0A8C2LHD1_CRIGR Computationally mapped isoform of Run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X4 OS=Cricetulus griseus OX=10029 GN=Rubcn PE=4 SV=1 CANONICAL=A0A9J7FV09-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FUM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09/entry#A0A9J7FUM9-1", "sequence": { "sequence": "MRPEGAGMDLGGGRERLPEESRREHWQLLGNLKTTVEGLVSANCPNVWSKYGGLERLCRDMQNILYHGLIHDQVCCRQADYWQFVKDIRWLSPHSALHVEKFINLHENGQSSADVSNRAVAELWLQHSLQSHCLSAQLRPLLGDRQYIRKFYTETAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPGSTYTPPASCAQQTYFGSSSNLHQSMPHHSSERRSTSFSLSGPPWKPQEDRDLSPAESQTAQAPLLSDPALAQDSPLTPHEMSSSTLTSPIEASWVSSQNDSPSDASEGPEYLAIGNPDPHGRTASCQSHSSNAESSSSHLFSSSSPQKPDSAASSLGDQEAGRQSQPGSVLRRSSFSEGQTVLVASGTKKSHIRSHSDTNIASKGATEGAQDLCSGESMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPAYQETEHGSFRVTSSSSQFSSRDSTQFSDSGSADDVDEFEIQDADIRRSTVSNGKSSISQNFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPGKALSSPMPVGGDLRGDYIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYSISNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFDVVPGHLTEDLHLYSLNDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEDDVIFPFELHKCRTCEECKACYHKVCFKSGRCPRCERLQARRELLAKQSLESYLSDYEEEPTEALALEATVLETT", "length": 953, "header": "tr|A0A9J7FUM9-1|A0A9J7FV09_CRIGR Computationally mapped isoform of Run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Rubcn PE=4 SV=1 CANONICAL=A0A9J7FV09-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FV09-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09/entry#A0A9J7FV09-1", "sequence": { "sequence": "MRPEGAGMDLGGGRERLPEESRREHWQLLGNLKTTVEGLVSANCPNVWSKYGGLERLCRDMQNILYHGLIHDQVCCRQADYWQFVKDIRWLSPHSALHVEKFINLHENGQSSADVSNRAVAELWLQHSLQSHCLSAQLRPLLGDRQYIRKFYTETAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPGSTYTPPASCAQQTYFGSSSNLHQSMPHHSSERRSTSFSLSGPPWKPQEDRDLSPAESQTAQAPLLSDPALAQDSPLTPHEMSSSTLTSPIEASWVSSQNDSPSDASEGPEYLAIGNPDPHGRTASCQSHSSNAESSSSHLFSSSSPQKPDSAASSLGDQEAGRQSQPGSVLRRSSFSEGQTVLVASGTKKSHIRSHSDTNIASKGATEGAQDLCSGESMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPAYQETEHGSFRVTSSSSQFSSRDSTQFSDSGSADDVDEFEIQDGSEGSNLTHMSKSGLSVSVASMFSDADIRRSTVSNGKSSISQNFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPGKALSSPMPVGGDLRGDYIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYSISNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFDVVPGHLTEDLHLYSLNDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEDDVIFPFELHKCRTCEECKACYHKVCFKSGRCPRCERLQARRELLAKQSLESYLSDYEEEPTEALALEATVLETT", "length": 978, "header": "tr|A0A9J7FV09-1|A0A9J7FV09_CRIGR Isoform 1 of Run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Rubcn PE=4 SV=1 CANONICAL=A0A9J7FV09-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09/entry#A0A9J7FZ40-1", "sequence": { "sequence": "MRPEGAGMDLGGGRERLPEESRREHWQLLGNLKTTVEGLVSANCPNVWSKYGGLERLCRDMQNILYHGLIHDQVCCRQADYWQFVKDIRWLSPHSALHVEKFINLHENGQSSADVSNRAVAELWLQHSLQSHCLSAQLRPLLGDRQYIRKFYTETAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPGSTYTPPASCAQQTYFGSSSNLHQSMPHHSSERRSTSFSLSGPPWKPQEDRDLSPAESQTAQAPLLSDPALAQDSPLTPHEMSSSTLTSPIEASWVSSQNDSPSDASEGPEYLAIGNPDPHGRTASCQSHSSNAESSSSHLFSSSSPQKPDSAASSLGDQEAGRQSQPGSVLRRSSFSEGQTVLVASGTKKSHIRSHSDTNIASKGATEGAQDLCSGESMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPAYQETEHGSFRVTSSSSQFSSRDSTQFSDSGSADDVDEFEIQDGSEGSNLTHMSKSGLSVSVASMFSDADIRRSTVSNGKSSISQNFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYSISNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFDVVPGHLTEDLHLYSLNDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEDDVIFPFELHKCRTCEECKACYHKVCFKSGRCPRCERLQARRELLAKQSLESYLSDYEEEPTEALALEATVLETT", "length": 962, "header": "tr|A0A9J7FZ40-1|A0A9J7FZ40_CRIGR Computationally mapped isoform of Run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X2 OS=Cricetulus griseus OX=10029 GN=Rubcn PE=4 SV=1 CANONICAL=A0A9J7FV09-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 965, "start_aa": "Thr", "end_pos": 965, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr965", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUM9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUM9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754353", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of autophagosome maturation", "id": "GO:1901097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901097", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09" } ], "pmid": "" }, { "name": "negative regulation of endocytosis", "id": "GO:0045806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045806", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol phosphate binding", "id": "GO:1901981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FV09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV09" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 188, "start_aa": "Trp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 965 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 310, "end_pos": 312 }, { "start_pos": 568, "end_pos": 570 }, { "start_pos": 605, "end_pos": 607 }, { "start_pos": 781, "end_pos": 783 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G017-1", "uniprot_ac": "A0A9J7G017", "uniprot_id": "A0A9J7G017_CRIGR", "mass": { "chemical_mass": 106383.0, "monoisotopic_mass": 106383.0 }, "refseq": { "ac": "XP_027269284", "name": "MICAL-like protein 2 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269284" }, "gene_names": [ { "name": "Micall2", "type": "recommended", "evidence": [ { "id": "A0A9J7G017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017" } ] }, { "name": "Micall2", "type": "synonym", "evidence": [ { "id": "XP_027269284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269284" } ] } ], "protein_names": [ { "name": "MICAL-like protein 2 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_027269284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269284" }, { "id": "A0A9J7G017", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269284" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G017", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Micall2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017", "locus": {} } ], "crossref": [ { "id": "A0A9J7G017", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G017", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09444", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09444", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21253", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21253", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771058", "url": "https://www.ncbi.nlm.nih.gov/gene/100771058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050540", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050540", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771058", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771058", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G017", "url": "https://www.orthodb.org/?gene=A0A9J7G017", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23167:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23167:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269284", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FUU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G017", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G017-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1E3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLH1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPB0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPB0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPB0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFSALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRPSSDSTEERSGKKVLTQPAKLPSPAPVQRSPLSPARTNPVVQRNEGTSEGSYPKAALGTAGSSMSSICGICGKHVHLVQRHLADGRLYHRSCFRCKQCSNTLHSGAYRATGEPGVFVCTHHSPEVASVSPKLSKLASRQSGAVAVDTRPFSASRKVQEANGLGEVTPLRVRAAAWEPSVGNTTAKGFVQTELNPPATSRVHVGSPAGPRLPTGPVATTSVNGKAITHVTNSSPTGWSSTAQSSSPATIGSRPAVYPSALDSHPSVPQGQATSKGVKTQLNLSTASPNTAATPAWTPVASRTQQAREKFFQNPTPAPSSNSPASKVPPVVNTSTSKVPPVVNTSTSKVTTVVNAPNGRVLPMVNTSTSKVSTVVIAPTSRVSTVVSATDGRVPTVVNAPTSKVPTVVNTHIGSIPAAVNAPASKVSAAVDTPAQESSREQALSVLRKALPGLTGAGTQAPSRSSPATSSVTITLPKNEVPQKVPSAKLSHSTISQAPASKMEPTAPLSVGNTQTGKKSLSASPGVGKTSAGSRPQAEVAVLKGPGSTSQEGQEEGPEGWRARLKPVDKKNTAGRTLGQKEVPSEPRAGDTPRKASSSSDTSIHVVLTPIQHKRTPRLADSGPSLPAAPSPSPSHRKKLTVPPSLDVSADWLQPELKKQETQAKNQKEEKTPTWRTREKPAVLDSALAPHGDTVTSPVRLHSNYIPQEELQRQLQDIESQLDALELRGVELEKRLRAAEGDAAEDSLMVDWFLLIHEKQLLLRLESELMYKSKDQRLEERQLDLQDELRRLIDKPEGLKSPGDRQREQELLSQYVNTVNDRSDIVDFLDEDRLREQEEDQMLENMIQNLGLQKKKSRFSFSKIWSSKSKGGQT", "length": 991, "header": "tr|A0A9J7G017-1|A0A9J7G017_CRIGR Isoform 1 of MICAL-like protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Micall2 PE=4 SV=1 CANONICAL=A0A9J7G017-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FUU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017/entry#A0A9J7FUU7-1", "sequence": { "sequence": "MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFSALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRPSSDSTEERSGKKVLTQPAKLPSPAPVQRSPLSPARTNPVVQRNEGTSEGSYPKAALGTAGSSMSSICGICGKHVHLVQRHLADGRLYHRSCFRCKQCSNTLHSGAYRATGEPGVFVCTHHSPEVASVSPKLSKLASRQSGAVAVDTRPFSASRKVQEANGLGEVTPLRVRAAAWEPSVGNTTAKGFVQTELNPPATSRVHVGSPAGPRLPTGPVATTSVNGKAITHVTNSSPTGWSSTAQSSSPATIGSRPAVYPSALDSHPSVPQGQATSKGVKTQLNLSTASPNTAATPAWTPVASRTQQAREKFFQNPTPAPSSNSPASKVPPVVNTSTSKVPPVVNTSTSKVTTVVNAPNGRVLPMVNTSTSKVSTVVIAPTSRVSTVVSATDGRVPTVVNAPTSKVPTVVNTHIGSIPAAVNAPASKVSAAVDTPAQESSREQALSVLRKALPGLTGAGTQAPSRSSPATSSVTITLPKNEVPQKVPSAKLSHSTISQAPASKMEPTAPLSVGNTQTGKKSLSASPGVGKTSAGSRPQAEVAVLKGPGSTSQEGQEEGPEGWRARLKPVDKKNTAGRTLGQKEVPSEPRAGDTPRKASSSSDTSIHVVLTPIQHKRTPRLADSGPSLPALMFLLIGSSQSSRSRKLRPRTRRRRRRPPGGQERSLQSWTVLLLHMVIL", "length": 794, "header": "tr|A0A9J7FUU7-1|A0A9J7G017_CRIGR Computationally mapped isoform of MICAL-like protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Micall2 PE=4 SV=1 CANONICAL=A0A9J7G017-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017/entry#A0A9J7FVB1-1", "sequence": { "sequence": "MMKLQCPPEGKHLREQQAVGGMAGVKRPSSDSTEERSGKKVLTQPAKLPSPAPVQRSPLSPARTNPVVQRNEGTSEGSYPKAALGTAGSSMSSICGICGKHVHLVQRHLADGRLYHRSCFRCKQCSNTLHSGAYRATGEPGVFVCTHHSPEVASVSPKLSKLASRQSGAVAVDTRPFSASRKVQEANGLGEVTPLRVRAAAWEPSVGNTTAKGFVQTELNPPATSRVHVGSPAGPRLPTGPVATTSVNGKAITHVTNSSPTGWSSTAQSSSPATIGSRPAVYPSALDSHPSVPQGQATSKGVKTQLNLSTASPNTAATPAWTPVASRTQQAREKFFQNPTPAPSSNSPASKVPPVVNTSTSKVPPVVNTSTSKVTTVVNAPNGRVLPMVNTSTSKVSTVVIAPTSRVSTVVSATDGRVPTVVNAPTSKVPTVVNTHIGSIPAAVNAPASKVSAAVDTPAQESSREQALSVLRKALPGLTGAGTQAPSRSSPATSSVTITLPKNEVPQKVPSAKLSHSTISQAPASKMEPTAPLSVGNTQTGKKSLSASPGVGKTSAGSRPQAEVAVLKGPGSTSQEGQEEGPEGWRARLKPVDKKNTAGRTLGQKEVPSEPRAGDTPRKASSSSDTSIHVVLTPIQHKRTPRLADSGPSLPAAPSPSPSHRKKLTVPPSLDVSADWLQPELKKQETQAKNQKEEKTPTWRTREKPAVLDSALAPHGDTVTSPVRLHSNYIPQEELQRQLQDIESQLDALELRGVELEKRLRAAEGDAAEDSLMVDWFLLIHEKQLLLRLESELMYKSKDQRLEERQLDLQDELRRLIDKPEGLKSPGDRQREQELLSQYVNTVNDRSDIVDFLDEDRLREQEEDQMLENMIQNLGLQKKKSRFSFSKIWSSKSKGGQT", "length": 898, "header": "tr|A0A9J7FVB1-1|A0A9J7FVB1_CRIGR Computationally mapped isoform of MICAL-like protein 2 isoform X12 OS=Cricetulus griseus OX=10029 GN=Micall2 PE=4 SV=1 CANONICAL=A0A9J7G017-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017/entry#A0A9J7FVK5-1", "sequence": { "sequence": "MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFSALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRPSSDSTEERSGKKVLTQPAKLPSPAPVQRSPLSPARTNPVVQRNEGTSEGSYPKAALGTAGSSMSSICGICGKHVHLVQRHLADGRLYHRSCFRCKQCSNTLHSGAYRATGEPGVFVCTHHSPEVASVSPKLSKLASRQSGAVAVDTRPFSASRKVQEANGLGEVTPLRVRAAAWEPSVGNTTAKGFVQTELNPPATSRVHVGSPAGPRLPTGPVATTSVNGKAITHVTNSSPTGWSSTAQSSSPATIGSRPAVYPSALDSHPSVPQGQATSKGVKTQLNLSTASPNTAATPAWTPVASRTQQAREKFFQNPTPAPSSNSPASKVPPVVNTSTSKVPPVVNTSTSKVTTVVNAPNGRVLPMVNTSTSKVSTVVIAPTSRVSTVVSATDGRVPTVVNAPTSKVPTVVNTHIGSIPAAVNAPASKVSAAVDTPAQESSREQALSVLRKALPGLTGAGTQAPSRSSPATSSVTITLPKNEVPQKVPSAKLSHSTISQAPASKMEPTAPLSVGNTQTGKKSLSASPGVGKTSAGSRPQAEVAVLKGPGSTSQEGQEEGPEGWRARLKPVDKKNTAGRTLGQKEVPSEPRAGDTPRKASSSSDTSIHVVLTPIQHKRTPRLADSGPSLPAPSPSPSHRKKLTVPPSLDVSADWLQPELKKQETQAKNQKEEKTPTWRTREKPAVLDSALAPHGDTVTSPVRLHSNYIPQEELQRQLQDIESQLDALELRGVELEKRLRAAEGDAAEDSLMVDWFLLIHEKQLLLRLESELMYKSKDQRLEERQLDLQDELRRLIDKPEGLKSPGDRQREQELLSQYVNTVNDRSDIVDFLDEDRLREQEEDQMLENMIQNLGLQKKKSRFSFSKIWSSKSKGGQT", "length": 990, "header": "tr|A0A9J7FVK5-1|A0A9J7FVK5_CRIGR Computationally mapped isoform of MICAL-like protein 2 isoform X7 OS=Cricetulus griseus OX=10029 GN=Micall2 PE=4 SV=1 CANONICAL=A0A9J7G017-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017/entry#A0A9J7FVQ0-1", "sequence": { "sequence": "MPQSLDFPRNLRVLAHKDVSAMKPPCSCQKLQCPPEGKHLREQQAVGGMAGVKRPSSDSTEERSGKKVLTQPAKLPSPAPVQRSPLSPARTNPVVQRNEGTSEGSYPKAALGTAGSSMSSICGICGKHVHLVQRHLADGRLYHRSCFRCKQCSNTLHSGAYRATGEPGVFVCTHHSPEVASVSPKLSKLASRQSGAVAVDTRPFSASRKVQEANGLGEVTPLRVRAAAWEPSVGNTTAKGFVQTELNPPATSRVHVGSPAGPRLPTGPVATTSVNGKAITHVTNSSPTGWSSTAQSSSPATIGSRPAVYPSALDSHPSVPQGQATSKGVKTQLNLSTASPNTAATPAWTPVASRTQQAREKFFQNPTPAPSSNSPASKVPPVVNTSTSKVPPVVNTSTSKVTTVVNAPNGRVLPMVNTSTSKVSTVVIAPTSRVSTVVSATDGRVPTVVNAPTSKVPTVVNTHIGSIPAAVNAPASKVSAAVDTPAQESSREQALSVLRKALPGLTGAGTQAPSRSSPATSSVTITLPKNEVPQKVPSAKLSHSTISQAPASKMEPTAPLSVGNTQTGKKSLSASPGVGKTSAGSRPQAEVAVLKGPGSTSQEGQEEGPEGWRARLKPVDKKNTAGRTLGQKEVPSEPRAGDTPRKASSSSDTSIHVVLTPIQHKRTPRLADSGPSLPAAPSPSPSHRKKLTVPPSLDVSADWLQPELKKQETQAKNQKEEKTPTWRTREKPAVLDSALAPHGDTVTSPVRLHSNYIPQEELQRQLQDIESQLDALELRGVELEKRLRAAEGDAAEDSLMVDWFLLIHEKQLLLRLESELMYKSKDQRLEERQLDLQDELRRLIDKPEGLKSPGDRQREQELLSQYVNTVNDRSDIVDFLDEDRLREQEEDQMLENMIQNLGLQKKKSRFSFSKIWSSKSKGGQT", "length": 925, "header": "tr|A0A9J7FVQ0-1|A0A9J7FVQ0_CRIGR Computationally mapped isoform of MICAL-like protein 2 isoform X9 OS=Cricetulus griseus OX=10029 GN=Micall2 PE=4 SV=1 CANONICAL=A0A9J7G017-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017/entry#A0A9J7FWR2-1", "sequence": { "sequence": "MAGVKRPSSDSTEERSGKKVLTQPAKLPSPAPVQRSPLSPARTNPVVQRNEGTSEGSYPKAALGTAGSSMSSICGICGKHVHLVQRHLADGRLYHRSCFRCKQCSNTLHSGAYRATGEPGVFVCTHHSPEVASVSPKLSKLASRQSGAVAVDTRPFSASRKVQEANGLGEVTPLRVRAAAWEPSVGNTTAKGFVQTELNPPATSRVHVGSPAGPRLPTGPVATTSVNGKAITHVTNSSPTGWSSTAQSSSPATIGSRPAVYPSALDSHPSVPQGQATSKGVKTQLNLSTASPNTAATPAWTPVASRTQQAREKFFQNPTPAPSSNSPASKVPPVVNTSTSKVPPVVNTSTSKVTTVVNAPNGRVLPMVNTSTSKVSTVVIAPTSRVSTVVSATDGRVPTVVNAPTSKVPTVVNTHIGSIPAAVNAPASKVSAAVDTPAQESSREQALSVLRKALPGLTGAGTQAPSRSSPATSSVTITLPKNEVPQKVPSAKLSHSTISQAPASKMEPTAPLSVGNTQTGKKSLSASPGVGKTSAGSRPQAEVAVLKGPGSTSQEGQEEGPEGWRARLKPVDKKNTAGRTLGQKEVPSEPRAGDTPRKASSSSDTSIHVVLTPIQHKRTPRLADSGPSLPAAPSPSPSHRKKLTVPPSLDVSADWLQPELKKQETQAKNQKEEKTPTWRTREKPAVLDSALAPHGDTVTSPVRLHSNYIPQEELQRQLQDIESQLDALELRGVELEKRLRAAEGDAAEDSLMVDWFLLIHEKQLLLRLESELMYKSKDQRLEERQLDLQDELRRLIDKPEGLKSPGDRQREQELLSQYVNTVNDRSDIVDFLDEDRLREQEEDQMLENMIQNLGLQKKKSRFSFSKIWSSKSKGGQT", "length": 877, "header": "tr|A0A9J7FWR2-1|A0A9J7FWR2_CRIGR Computationally mapped isoform of MICAL-like protein 2 isoform X13 OS=Cricetulus griseus OX=10029 GN=Micall2 PE=4 SV=1 CANONICAL=A0A9J7G017-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G017-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017/entry#A0A9J7G017-1", "sequence": { "sequence": "MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFSALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRPSSDSTEERSGKKVLTQPAKLPSPAPVQRSPLSPARTNPVVQRNEGTSEGSYPKAALGTAGSSMSSICGICGKHVHLVQRHLADGRLYHRSCFRCKQCSNTLHSGAYRATGEPGVFVCTHHSPEVASVSPKLSKLASRQSGAVAVDTRPFSASRKVQEANGLGEVTPLRVRAAAWEPSVGNTTAKGFVQTELNPPATSRVHVGSPAGPRLPTGPVATTSVNGKAITHVTNSSPTGWSSTAQSSSPATIGSRPAVYPSALDSHPSVPQGQATSKGVKTQLNLSTASPNTAATPAWTPVASRTQQAREKFFQNPTPAPSSNSPASKVPPVVNTSTSKVPPVVNTSTSKVTTVVNAPNGRVLPMVNTSTSKVSTVVIAPTSRVSTVVSATDGRVPTVVNAPTSKVPTVVNTHIGSIPAAVNAPASKVSAAVDTPAQESSREQALSVLRKALPGLTGAGTQAPSRSSPATSSVTITLPKNEVPQKVPSAKLSHSTISQAPASKMEPTAPLSVGNTQTGKKSLSASPGVGKTSAGSRPQAEVAVLKGPGSTSQEGQEEGPEGWRARLKPVDKKNTAGRTLGQKEVPSEPRAGDTPRKASSSSDTSIHVVLTPIQHKRTPRLADSGPSLPAAPSPSPSHRKKLTVPPSLDVSADWLQPELKKQETQAKNQKEEKTPTWRTREKPAVLDSALAPHGDTVTSPVRLHSNYIPQEELQRQLQDIESQLDALELRGVELEKRLRAAEGDAAEDSLMVDWFLLIHEKQLLLRLESELMYKSKDQRLEERQLDLQDELRRLIDKPEGLKSPGDRQREQELLSQYVNTVNDRSDIVDFLDEDRLREQEEDQMLENMIQNLGLQKKKSRFSFSKIWSSKSKGGQT", "length": 991, "header": "tr|A0A9J7G017-1|A0A9J7G017_CRIGR Isoform 1 of MICAL-like protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Micall2 PE=4 SV=1 CANONICAL=A0A9J7G017-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017/entry#A0A9J7H1E3-1", "sequence": { "sequence": "MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFSALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRPSSDSTEERSGKKVLTQPAKLPSPAPVQRSPLSPARTNPVVQRNEGTSEGSYPKAALGTAGSSMSSICGICGKHVHLVQRHLADGRLYHRSCFRCKQCSNTLHSGAYRATGEPGVFVCTHHSPEVASVSPKLSKLASRQSGAVAVDTRPFSASRKVQEANGLGEVTPLRVRAAAWEPSVGNTTAKGFVQTELNPPATSRVHVGSPAGPRLPTGPVATTSVNGKAITHVTNSSPTGWSSTAQSSSPATIGSRPAVYPSALDSHPSVPQGQATSKGVKTQLNLSTASPNTAATPAWTPVASRTQQAREKFFQNPTPAPSSNSPASKVPPVVNTSTSKVPPVVNTSTSKVTTVVNAPNGRVLPMVNTSTSKVSTVVIAPTSRVSTVVSATDGRVPTVVNAPTSKVPTVVNTHIGSIPAAVNAPASKVSAAVDTPAQESSREQALSVLRKALPGLTGAGTQAPSRSSPATSSVTITLPKNEVPQKVPSAKLSHSTISQAPASKMEPTAPLSVGNTQTGKKSLSASPGVGKTSAGSRPQAEVAVLKGPGSTSQEGQEEGPEGWRARLKPVDKKNTAGRTLGQKEVPSEPRAGDTPRKASSSSDTSIHVVLTPIQHKRTPRLADSGPSLPAAPSPSPSHRKKLTVPPSLDVSADWLQPELKKQETQAKNQKEEKTPTWRTREKPAVLDSALAPHGDTVTSPVRLHSNYIPQEELQRQLQDIESQLDALELRGVELEKRLRAAEGDAAEDSLMVDWFLLIHEKQLLLRLESELMYKSKDQRLEERQLDLQDELRRLIDKPGNKKRTKCWRT", "length": 924, "header": "tr|A0A9J7H1E3-1|A0A9J7H1E3_CRIGR Computationally mapped isoform of MICAL-like protein 2 isoform X10 OS=Cricetulus griseus OX=10029 GN=Micall2 PE=4 SV=1 CANONICAL=A0A9J7G017-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017/entry#A0A9J7JLH1-1", "sequence": { "sequence": "MAAIKALQEWCRQQCEGYRDVSITNMTTSFRDGLAFCAILHRHRPDLINFSALRKENIYENNKLAFQVAEEQLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRPSSDSTEERSGKKVLTQPAKLPSPAPVQRSPLSPARTNPVVQRNEGTSEGSYPKAALGTAGSSMSSICGICGKHVHLVQRHLADGRLYHRSCFRCKQCSNTLHSGAYRATGEPGVFVCTHHSPEVASVSPKLSKLASRQSGAVAVDTRPFSASRKVQEANGLGEVTPLRVRAAAWEPSVGNTTAKGFVQTELNPPATSRVHVGSPAGPRLPTGPVATTSVNGKAITHVTNSSPTGWSSTAQSSSPATIGSRPAVYPSALDSHPSVPQGQATSKGVKTQLNLSTASPNTAATPAWTPVASRTQQAREKFFQNPTPAPSSNSPASKVPPVVNTSTSKVPPVVNTSTSKVTTVVNAPNGRVLPMVNTSTSKVSTVVIAPTSRVSTVVSATDGRVPTVVNAPTSKVPTVVNTHIGSIPAAVNAPASKVSAAVDTPAQESSREQALSVLRKALPGLTGAGTQAPSRSSPATSSVTITLPKNEVPQKVPSAKLSHSTISQAPASKMEPTAPLSVGNTQTGKKSLSASPGVGKTSAGSRPQAEVAVLKGPGSTSQEGQEEGPEGWRARLKPVDKKNTAGRTLGQKEVPSEPRAGDTPRKASSSSDTSIHVVLTPIQHKRTPRLADSGPSLPAAPSPSPSHRKKLTVPPSLDVSADWLQPELKKQETQAKNQKEEKTPTWRTREKPAVLDSALAPHGDTVTSPVREELQRQLQDIESQLDALELRGVELEKRLRAAEGDAAEDSLMVDWFLLIHEKQLLLRLESELMYKSKDQRLEERQLDLQDELRRLIDKPEGLKSPGDRQREQELLSQYVNTVNDRSDIVDFLDEDRLREQEEDQMLENMIQNLGLQKKKSRFSFSKIWSSKSKGGQT", "length": 983, "header": "tr|A0A9J7JLH1-1|A0A9J7JLH1_CRIGR Computationally mapped isoform of MICAL-like protein 2 isoform X8 OS=Cricetulus griseus OX=10029 GN=Micall2 PE=4 SV=1 CANONICAL=A0A9J7G017-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPB0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017/entry#A0A9J7JPB0-1", "sequence": { "sequence": "MVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRPSSDSTEERSGKKVLTQPAKLPSPAPVQRSPLSPARTNPVVQRNEGTSEGSYPKAALGTAGSSMSSICGICGKHVHLVQRHLADGRLYHRSCFRCKQCSNTLHSGAYRATGEPGVFVCTHHSPEVASVSPKLSKLASRQSGAVAVDTRPFSASRKVQEANGLGEVTPLRVRAAAWEPSVGNTTAKGFVQTELNPPATSRVHVGSPAGPRLPTGPVATTSVNGKAITHVTNSSPTGWSSTAQSSSPATIGSRPAVYPSALDSHPSVPQGQATSKGVKTQLNLSTASPNTAATPAWTPVASRTQQAREKFFQNPTPAPSSNSPASKVPPVVNTSTSKVPPVVNTSTSKVTTVVNAPNGRVLPMVNTSTSKVSTVVIAPTSRVSTVVSATDGRVPTVVNAPTSKVPTVVNTHIGSIPAAVNAPASKVSAAVDTPAQESSREQALSVLRKALPGLTGAGTQAPSRSSPATSSVTITLPKNEVPQKVPSAKLSHSTISQAPASKMEPTAPLSVGNTQTGKKSLSASPGVGKTSAGSRPQAEVAVLKGPGSTSQEGQEEGPEGWRARLKPVDKKNTAGRTLGQKEVPSEPRAGDTPRKASSSSDTSIHVVLTPIQHKRTPRLADSGPSLPAAPSPSPSHRKKLTVPPSLDVSADWLQPELKKQETQAKNQKEEKTPTWRTREKPAVLDSALAPHGDTVTSPVRLHSNYIPQEELQRQLQDIESQLDALELRGVELEKRLRAAEGDAAEDSLMVDWFLLIHEKQLLLRLESELMYKSKDQRLEERQLDLQDELRRLIDKPEGLKSPGDRQREQELLSQYVNTVNDRSDIVDFLDEDRLREQEEDQMLENMIQNLGLQKKKSRFSFSKIWSSKSKGGQT", "length": 908, "header": "tr|A0A9J7JPB0-1|A0A9J7JPB0_CRIGR Computationally mapped isoform of MICAL-like protein 2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Micall2 PE=4 SV=1 CANONICAL=A0A9J7G017-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 411, "start_aa": "Thr", "end_pos": 411, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr411", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUU7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUU7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771058", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771058", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G017", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G017" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G017", "url": 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initiation factor eIF2B subunit epsilon", "type": "recommended", "evidence": [ { "id": "A0A9J7FZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5/entry#names_and_taxonomy" } ] }, { "name": "eIF2B GDP-GTP exchange factor subunit epsilon", "type": "synonym", "evidence": [ { "id": "A0A9J7FZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5/entry#names_and_taxonomy" } ] }, { "name": "translation initiation factor eIF-2B subunit epsilon isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027268866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268866" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268866" } ] }, { "annotation": "Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUZ9#function" }, { "database": "UniProtKB", "id": "ARBA00043898", "url": "https://www.uniprot.org/uniprotkb/ARBA00043898#function" }, { "database": "UniProtKB", "id": "A0A9J7FZF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": 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"categories": [ "Protein Classification" ] }, { "id": "IPR011004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056764", "url": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268866", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FUZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FUZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATAALPGPAAGRVNKRGGGPGGGGTQGAEEEPPPPLQAVLVADSFNRRFFPISKDQPRVLLPLANVALIDYTLEFLTASGVQETFVFCCWKAAQIKEHLLKSKWCHPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLIYGDVVSNINITRALEEHRLRRKLQKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSATNRILHFQKTQGLRRFSFPLNLFQGSRDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHLHVTTKEYGARVSNLHMYSAVCADIIRRWVYPLTPEVNFTDSTAQSYTHSRHNIYRGPQVSLGHGSVLEENVLLGAGTVIGSNCSITNSVIGPNCHIGDNVVLDRAYLWQGVRVASGSQIHQSLLCDKAEVKERVTLKPHCVLTSQVVVGPDITLPEGSVISLHPPDAEEDEDDGQFSDDSGADQEKEKVKLKGYNPAEVGFEGQGYLWKAADVNMEEEEELRQSLWGLTINMEDESETESERSMDSEELDSRAVSPQLDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSLLDPNRYCAMLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHETLVTSMAKVLMAFYQLEILAEETILSWFSQRDITDKGQQLRKNGQLQRFIQWLKEAEEESSEDD", "length": 716, "header": "tr|A0A9J7FZF5-1|A0A9J7FZF5_CRIGR Isoform 1 of Translation initiation factor eIF2B subunit epsilon OS=Cricetulus griseus OX=10029 GN=Eif2b5 PE=3 SV=1 CANONICAL=A0A9J7FZF5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FUZ9-1", "url": 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{} }, { "isoform_ac": "A0A9J7FZF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5/entry#A0A9J7FZF5-1", "sequence": { "sequence": "MAATAALPGPAAGRVNKRGGGPGGGGTQGAEEEPPPPLQAVLVADSFNRRFFPISKDQPRVLLPLANVALIDYTLEFLTASGVQETFVFCCWKAAQIKEHLLKSKWCHPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLIYGDVVSNINITRALEEHRLRRKLQKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSATNRILHFQKTQGLRRFSFPLNLFQGSRDGVEIRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGLLVNEEILGNQIHLHVTTKEYGARVSNLHMYSAVCADIIRRWVYPLTPEVNFTDSTAQSYTHSRHNIYRGPQVSLGHGSVLEENVLLGAGTVIGSNCSITNSVIGPNCHIGDNVVLDRAYLWQGVRVASGSQIHQSLLCDKAEVKERVTLKPHCVLTSQVVVGPDITLPEGSVISLHPPDAEEDEDDGQFSDDSGADQEKEKVKLKGYNPAEVGFEGQGYLWKAADVNMEEEEELRQSLWGLTINMEDESETESERSMDSEELDSRAVSPQLDDIKVFQNEVLGTLQRGKEENISCDNLVLEINSLKYAYNISLKEVMQVLSHVVLEFPLQQMDSLLDPNRYCAMLLPLLKAWSPVFRNYIKRAADHLEALAAIEDFFLEHETLVTSMAKVLMAFYQLEILAEETILSWFSQRDITDKGQQLRKNGQLQRFIQWLKEAEEESSEDD", "length": 716, "header": "tr|A0A9J7FZF5-1|A0A9J7FZF5_CRIGR Isoform 1 of Translation initiation factor eIF2B subunit epsilon OS=Cricetulus griseus OX=10029 GN=Eif2b5 PE=3 SV=1 CANONICAL=A0A9J7FZF5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUZ9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FUZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUZ9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773826", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773826", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2B complex", "id": "GO:0005851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005851", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5" } ], "pmid": "" }, { "name": "translation initiation factor binding", "id": "GO:0031369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031369", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, 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"A0A9J7FZF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF5" }, { "id": "PS51363", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51363" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "W2", "eco_id": "ECO_0000259", "start_pos": 538, "end_pos": 715, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 563, "end_pos": 565 }, { "start_pos": 581, "end_pos": 583 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FZG6-1", "uniprot_ac": "A0A9J7FZG6", "uniprot_id": "A0A9J7FZG6_CRIGR", "mass": { "chemical_mass": 149324.0, "monoisotopic_mass": 149324.0 }, "refseq": { "ac": "XP_027268882", "name": "YEATS domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268882" }, "gene_names": [ { "name": "Yeats2", "type": "recommended", "evidence": [ { "id": "A0A9J7FZG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6" } ] }, { "name": "Yeats2", "type": "synonym", "evidence": [ { "id": "XP_027268882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268882" } ] } ], "protein_names": [ { "name": "YEATS domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0A9J7FZG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6/entry#names_and_taxonomy" } ] }, { "name": "YEATS domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027268882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268882" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268882" } ] }, { "annotation": "Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV08#function" }, { "database": "UniProtKB", "id": "ARBA00060245", "url": "https://www.uniprot.org/uniprotkb/ARBA00060245#function" }, { "database": "UniProtKB", "id": "A0A9J7FZG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6#function" }, { "database": "UniProtKB", "id": "A0A9J7JL67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JL67#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Yeats2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6", "locus": {} } ], "crossref": [ { "id": "cd16907", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16907", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759076", "url": "https://www.ncbi.nlm.nih.gov/gene/100759076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005033", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005033", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759076", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FZG6", "url": "https://www.orthodb.org/?gene=A0A9J7FZG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23195", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23195", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22951", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22951", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268882", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268882", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FV08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV08-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JL67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JL67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JL67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JL67-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGIKRTIKETDPDYEDVSVALPNKRHKAIESSARDAAVQKIETIIKEQFALEMKNKEHEIDVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGLKTFDTMAFNHPAIKKFLESPSRSSSPTNQRSETPSANHSESDSLSQHNDFLSDKDNNSNMDVEERLSTTMEQRSSRNPGRDTSSVSGSHKRELRNADLTGDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDYIYPQSSESDISDAPPSLTIPAPVKASPVARSPEPASAAPAGEGFPDNPEAERHTTFYSLPSSLERTPTKVTTTQKVTFCSHGNSAFQPIASSCKIVPQSQAPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHVKQGTTSSGINNPHIIVDKPGQIIGASTPSTGSPTSKLPVASQVPQGTGSPIPKIHGSSFLTSTVKQEDSLFASMPPLCPIGSHPKVQSPKAVTGGLGAFTKVIIKQEPGEAPHVSTTGAASQSTFPQYVTVKGGHMIAVSPQKQVVSAGEGTTQSPKIPPSKVVGVPVGSTLPSTVKQAVAISSGQILVAKASSSVTKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKTQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSTAAGGSGSSGGGAGGGGSGGGGGSGAGGTPSTTGPGGVSQHLTYTSYILKQTPQGTFLVGQPSPQTPGKQLTTSVVQGTLGVGSPSAQGQQTLKVISGQKTTLFTQAATAGQASLVKLPDNTLKSVPAAASQLAKPGTTMLRVAGGVITAAPSPAVAFSTNGAAHQPEGSAPVSSSVSSIIKTPGQPQVCVSQATMGTCKGTAPSAISAASLVSTPSPISGKATVSGLLKIHSGQSSPQQAVLTIPSQLKPLSINTSGGVQTVLMPVNKVVQSFSTSKLPTVLPISVPSPAAPSSAPVAIAKVKTEPEIPGPNCLSQEGQAAVKTEESSELGTYVIKVDHLETIQQLLTAVVKKIPLITSKGDDASCFSAKSIEQYYGWNIGKRRAAEWQRAMTVRKVLQEILEKNPRFHHLTPLKTKNIAHWCRCHGYTPPDPESLRHDGDSIEDVLTRIDSEPECLSSFSTADDLCRKLEDLQQFQKREPENEEEVDVLSLSEPLKTNIKKEQEEKQEEMRFYLPPTLGSGFVGDITQKIGITLQPVALHKNTYASVVEDMILKATEQLVSDILRQALAVGYQTASPNRVPKEITVSNIHQAICNIPFLDFLTNKYMGRLNEDQ", "length": 1408, "header": "tr|A0A9J7FZG6-1|A0A9J7FZG6_CRIGR Isoform 1 of YEATS domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Yeats2 PE=4 SV=1 CANONICAL=A0A9J7FZG6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FV08-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6/entry#A0A9J7FV08-1", "sequence": { "sequence": "MRMCLWPFQISGIKRLRVQRLIEARRMMDKLRACIVANYYASAGLLKVSEGLKTFDTMAFNHPAIKKFLESPSRSSSPTNQRSETPSANHSESDSLSQHNDFLSDKDNNSNMDVEERLSTTMEQRSSRNPGRDTSSVSGSHKRELRNADLTGDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDYIYPQSSESDISDAPPSLTIPAPVKASPVARSPEPASAAPAGEGFPDNPEAERHTTFYSLPSSLERTPTKVTTTQKVTFCSHGNSAFQPIASSCKIVPQSQAPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHVKQGTTSSGINNPHIIVDKPGQIIGASTPSTGSPTSKLPVASQVPQGTGSPIPKIHGSSFLTSTVKQEDSLFASMPPLCPIGSHPKVQSPKAVTGGLGAFTKVIIKQEPGEAPHVSTTGAASQSTFPQYVTVKGGHMIAVSPQKQVVSAGEGTTQSPKIPPSKVVGVPVGSTLPSTVKQAVAISSGQILVAKASSSVTKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKTQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSTAAGGSGSSGGGAGGGGSGGGGGSGAGGTPSTTGPGGVSQHLTYTSYILKQTPQGTFLVGQPSPQTPGKQLTTSVVQGTLGVGSPSAQGQQTLKVISGQKTTLFTQAATAGQASLVKLPDNTLKSVPAAASQLAKPGTTMLRVAGGVITAAPSPAVAFSTNGAAHQPEGSAPVSSSVSSIIKTPGQPQVCVSQATMGTCKGTAPSAISAASLVSTPSPISGKATVSGLLKIHSGQSSPQQAVLTIPSQLKPLSINTSGGVQTVLMPVNKVVQSFSTSKLPTVLPISVPSPAAPSSAPVAIAKVKTEPEIPGPNCLSQEGQAAVKTEESSELGTYVIKVDHLETIQQLLTAVVKKIPLITSKGDDASCFSAKSIEQYYGWNIGKRRAAEWQRAMTVRKVLQEILEKNPRFHHLTPLKTKNIAHWCRCHGYTPPDPESLRHDGDSIEDVLTRIDSEPECLSSFSTADDLCRKLEDLQQFQKREPENEEEVDVLSLSEPLKTNIKKEQEEKQEEMRFYLPPTLGSGFVGDITQKIGITLQPVALHKNTYASVVEDMILKATEQLVSDILRQALAVGYQTASPNRVPKEITVSNIHQAICNIPFLDFLTNKYMGRLNEDQ", "length": 1361, "header": "tr|A0A9J7FV08-1|A0A9J7FZG6_CRIGR Computationally mapped isoform of YEATS domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Yeats2 PE=4 SV=1 CANONICAL=A0A9J7FZG6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6/entry#A0A9J7FZG6-1", "sequence": { "sequence": "MSGIKRTIKETDPDYEDVSVALPNKRHKAIESSARDAAVQKIETIIKEQFALEMKNKEHEIDVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGLKTFDTMAFNHPAIKKFLESPSRSSSPTNQRSETPSANHSESDSLSQHNDFLSDKDNNSNMDVEERLSTTMEQRSSRNPGRDTSSVSGSHKRELRNADLTGDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDYIYPQSSESDISDAPPSLTIPAPVKASPVARSPEPASAAPAGEGFPDNPEAERHTTFYSLPSSLERTPTKVTTTQKVTFCSHGNSAFQPIASSCKIVPQSQAPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHVKQGTTSSGINNPHIIVDKPGQIIGASTPSTGSPTSKLPVASQVPQGTGSPIPKIHGSSFLTSTVKQEDSLFASMPPLCPIGSHPKVQSPKAVTGGLGAFTKVIIKQEPGEAPHVSTTGAASQSTFPQYVTVKGGHMIAVSPQKQVVSAGEGTTQSPKIPPSKVVGVPVGSTLPSTVKQAVAISSGQILVAKASSSVTKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKTQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSTAAGGSGSSGGGAGGGGSGGGGGSGAGGTPSTTGPGGVSQHLTYTSYILKQTPQGTFLVGQPSPQTPGKQLTTSVVQGTLGVGSPSAQGQQTLKVISGQKTTLFTQAATAGQASLVKLPDNTLKSVPAAASQLAKPGTTMLRVAGGVITAAPSPAVAFSTNGAAHQPEGSAPVSSSVSSIIKTPGQPQVCVSQATMGTCKGTAPSAISAASLVSTPSPISGKATVSGLLKIHSGQSSPQQAVLTIPSQLKPLSINTSGGVQTVLMPVNKVVQSFSTSKLPTVLPISVPSPAAPSSAPVAIAKVKTEPEIPGPNCLSQEGQAAVKTEESSELGTYVIKVDHLETIQQLLTAVVKKIPLITSKGDDASCFSAKSIEQYYGWNIGKRRAAEWQRAMTVRKVLQEILEKNPRFHHLTPLKTKNIAHWCRCHGYTPPDPESLRHDGDSIEDVLTRIDSEPECLSSFSTADDLCRKLEDLQQFQKREPENEEEVDVLSLSEPLKTNIKKEQEEKQEEMRFYLPPTLGSGFVGDITQKIGITLQPVALHKNTYASVVEDMILKATEQLVSDILRQALAVGYQTASPNRVPKEITVSNIHQAICNIPFLDFLTNKYMGRLNEDQ", "length": 1408, "header": "tr|A0A9J7FZG6-1|A0A9J7FZG6_CRIGR Isoform 1 of YEATS domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Yeats2 PE=4 SV=1 CANONICAL=A0A9J7FZG6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JL67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6/entry#A0A9J7JL67-1", "sequence": { "sequence": "MSGIKRTIKETDPDYEDVSVALPNKRHKAIESSARDAAVQKIETIIKEQFALEMKNKEHEIDVIDQRLIEARRMMDKLRACIVANYYASAGLLKVSEGLKTFDTMAFNHPAIKKFLESPSRSSSPTNQRSETPSANHSESDSLSQHNDFLSDKDNNSNMDVEERLSTTMEQRSSRNPGRDTSSVSGSHKRELRNADLTGDETSRLFVKKTIVVGNVSKYIPPDKREENDQSTHKWMVYVRGSRREPSINHFVKKVWFFLHPSYKPNDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLKLDRTYTGLQTLGAETVVDVELHRHSLGEDYIYPQSSESDISDAPPSLTIPAPVKASPVARSPEPASAAPAGEGFPDNPEAERHTTFYSLPSSLERTPTKVTTTQKVTFCSHGNSAFQPIASSCKIVPQSQAPNPESPGKSFQPITMSCKIVSGSPISTPSPSPLPRTPTSTPVHVKQGTTSSGINNPHIIVDKPGQIIGASTPSTGSPTSKLPVASQVPQGTGSPIPKIHGSSFLTSTVKQEDSLFASMPPLCPIGSHPKVQSPKAVTGGLGAFTKVIIKQEPGEAPHVSTTGAASQSTFPQYVTVKGGHMIAVSPQKQVVSAGEGTTQSPKIPPSKVVGVPVGSTLPSTVKQAVAISSGQILVAKASSSVTKAVGPKQVVTQGVAKAIVSGGGGTIVAQPVQTLTKTQVTAAGPQKSGSQGSVMATLQLPATNLANLANLPPGTKLYLTTNSKNPSGKGKLLLIPQGAILRATNNANLQSGSTAAGGSGSSGGGAGGGGSGGGGGSGAGGTPSTTGPGGVSQHLTYTSYILKQTPQGTFLVGQPSPQTPGKQLTTSVVQGTLGVGSPSAQGQQTLKVISGQKTTLFTQAATAGQASLVKLPDNTLKSVPAAASQLAKPGTTMLRVAGGVITAAPSPAVAFSTNGAAHQPEGSAPVSSSVSSIIKTPGQPQVCVSQATMGTCKGTAPSAISAASLVSTPSPISGKATVSGLLKIHSGQSSPQQAVLTIPSQLKPLSINTSGGVQTVLMPVNKVVQSFSTSKLPTVLPISVPSPAAPSSAPVAIAKVKTEPEIPGPNCLSQEGQAAVKTEESSELGTYVIKVDHLETIQQLLTAVVKKIPLITSKGDDASCFSAKSIEQYYGWNIGKRRAAEWQRAMTVRKVLQEILEKNPRFHHLTPLKTKNIAHWCRCHGYTPPDPESLRHDGDSIEDVLTRIDSEPDRIHLE", "length": 1253, "header": "tr|A0A9J7JL67-1|A0A9J7JL67_CRIGR Computationally mapped isoform of YEATS domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Yeats2 PE=4 SV=1 CANONICAL=A0A9J7FZG6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 821, "start_aa": "Thr", "end_pos": 821, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr821", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV08" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV08" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759076", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759076", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6" } ], "pmid": "" }, { "name": "ATAC complex", "id": "GO:0140672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140672", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6" } ], "pmid": "" }, { "name": "regulation of cell division", "id": "GO:0051302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051302", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1047, "end_pos": 1049, "annotation": 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"Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 821 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1047, "end_pos": 1049 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 215, "end_pos": 217 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", 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"uniprot_canonical_ac": "A0A9J7FV12-1", "uniprot_ac": "A0A9J7FV12", "uniprot_id": "A0A9J7FV12_CRIGR", "mass": { "chemical_mass": 22619.0, "monoisotopic_mass": 22619.0 }, "refseq": { "ac": "XP_027269113", "name": "keratin-associated protein 27-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269113" }, "gene_names": [ { "name": "LOC100773074", "type": "recommended", "evidence": [ { "id": "A0A9J7FV12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12" } ] }, { "name": "LOC100773074", "type": "synonym", "evidence": [ { "id": "XP_027269113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269113" } ] } ], "protein_names": [ { "name": "Keratin-associated protein", "type": "recommended", "evidence": [ { "id": "A0A9J7FV12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12/entry#names_and_taxonomy" } ] }, { "name": "keratin-associated protein 27-1", "type": "synonym", "evidence": [ { "id": "XP_027269113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269113" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269113" } ] }, { "annotation": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12#function" }, { "database": "UniProtKB", "id": "RU369044", "url": "https://www.uniprot.org/uniprotkb/RU369044#function" }, { "database": "UniProtKB", "id": "ARBA00003327", "url": "https://www.uniprot.org/uniprotkb/ARBA00003327#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773074", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12", "locus": {} } ], "crossref": [ { "id": "A0A9J7FV12", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FV12", "database": "AlphaFoldDB", "categories": [] }, { "id": "100773074", "url": "https://www.ncbi.nlm.nih.gov/gene/100773074", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773074", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773074", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FV12", "url": "https://www.orthodb.org/?gene=A0A9J7FV12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23260:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23260:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05287", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05287", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269113", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269113", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FV12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV12-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPHSYCQSFRSLGKAPSLSAITHNSNPKSFEDGIFLPSSCHSRTWLLGNFQETYNETSTHQPTTCEQHQCKEDCCVQNSWISRADQTTWSNSKTCEKTTYQSGISPEVPECASQPCQSRNCQQVGLVVQSYHLPSSYMAKCYPLKSTMSESCQTVEFESSQCYSQVSESSSCKSSSNAVSGTQLVESSSTYEPACCVTGGSKLPSK", "length": 206, "header": "tr|A0A9J7FV12-1|A0A9J7FV12_CRIGR Isoform 1 of Keratin-associated protein OS=Cricetulus griseus OX=10029 GN=LOC100773074 PE=3 SV=1 CANONICAL=A0A9J7FV12-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FV12-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12/entry#A0A9J7FV12-1", "sequence": { "sequence": "MPHSYCQSFRSLGKAPSLSAITHNSNPKSFEDGIFLPSSCHSRTWLLGNFQETYNETSTHQPTTCEQHQCKEDCCVQNSWISRADQTTWSNSKTCEKTTYQSGISPEVPECASQPCQSRNCQQVGLVVQSYHLPSSYMAKCYPLKSTMSESCQTVEFESSQCYSQVSESSSCKSSSNAVSGTQLVESSSTYEPACCVTGGSKLPSK", "length": 206, "header": "tr|A0A9J7FV12-1|A0A9J7FV12_CRIGR Isoform 1 of Keratin-associated protein OS=Cricetulus griseus OX=10029 GN=LOC100773074 PE=3 SV=1 CANONICAL=A0A9J7FV12-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773074", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773074", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV12" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV12", "url": 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"class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVH7-1", "uniprot_ac": "A0A9J7FVH7", "uniprot_id": "A0A9J7FVH7_CRIGR", "mass": { "chemical_mass": 30255.0, "monoisotopic_mass": 30255.0 }, "refseq": { "ac": "XP_007648507", "name": "cleavage and polyadenylation specificity factor subunit 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648507" }, "gene_names": [ { "name": "Cpsf4", "type": "recommended", "evidence": [ { "id": "A0A9J7FVH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7" } ] }, { "name": "Cpsf4", "type": "synonym", "evidence": [ { "id": "XP_007648507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648507" } ] } ], "protein_names": [ { "name": "Cleavage and polyadenylation specificity factor subunit 4", "type": "recommended", "evidence": [ { "id": "A0A9J7FVH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7/entry#names_and_taxonomy" } ] }, { "name": "CPSF 30 kDa subunit", "type": "synonym", "evidence": [ { "id": "A0A9J7FVH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7/entry#names_and_taxonomy" } ] }, { "name": "Cleavage and polyadenylation specificity factor 30 kDa subunit", "type": "synonym", "evidence": [ { "id": "A0A9J7FVH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7/entry#names_and_taxonomy" } ] }, { "name": "cleavage and polyadenylation specificity factor subunit 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007648507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648507" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614752.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007648507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648507" } ] }, { "annotation": "Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. 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"IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041686", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041686", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773929", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773929", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEVTCFK", "url": "https://omabrowser.org/oma/group/EEVTCFK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N1E3", "url": "https://www.orthodb.org/?gene=A0A8C2N1E3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FV13", "url": "https://www.orthodb.org/?gene=A0A9J7FV13", "database": "OrthoDB", "categories": [ "Protein 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"https://www.uniprot.org/uniprotkb/A0A9J7FVH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPTKQSNNPPLQRSSSLIQLTSQNSSPNQQRAPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ", "length": 269, "header": "tr|A0A9J7FVH7-1|A0A9J7FVH7_CRIGR Isoform 1 of Cleavage and polyadenylation specificity factor subunit 4 OS=Cricetulus griseus OX=10029 GN=Cpsf4 PE=3 SV=1 CANONICAL=A0A9J7FVH7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N1E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7/entry#A0A8C2N1E3-1", "sequence": { "sequence": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPTKQRAPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ", "length": 244, "header": "tr|A0A8C2N1E3-1|A0A8C2N1E3_CRIGR Computationally mapped isoform of Cleavage and polyadenylation specificity factor subunit 4 OS=Cricetulus griseus OX=10029 GN=Cpsf4 PE=3 SV=1 CANONICAL=A0A9J7FVH7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FV13-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7/entry#A0A9J7FV13-1", "sequence": { "sequence": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPTKRAPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ", "length": 243, "header": "tr|A0A9J7FV13-1|A0A9J7FVH7_CRIGR Computationally mapped isoform of Cleavage and polyadenylation specificity factor subunit 4 OS=Cricetulus griseus OX=10029 GN=Cpsf4 PE=3 SV=1 CANONICAL=A0A9J7FVH7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7/entry#A0A9J7FVH7-1", "sequence": { "sequence": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPTKQSNNPPLQRSSSLIQLTSQNSSPNQQRAPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ", "length": 269, "header": "tr|A0A9J7FVH7-1|A0A9J7FVH7_CRIGR Isoform 1 of Cleavage and polyadenylation specificity factor subunit 4 OS=Cricetulus griseus OX=10029 GN=Cpsf4 PE=3 SV=1 CANONICAL=A0A9J7FVH7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZ46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7/entry#A0A9J7FZ46-1", "sequence": { "sequence": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPTKCQSLKWPAQDLPPPSGDGGTKQIRLPEESQAVRGTGAADCLGGS", "length": 234, "header": "tr|A0A9J7FZ46-1|A0A9J7FZ46_CRIGR Computationally mapped isoform of Cleavage and polyadenylation specificity factor subunit 4 OS=Cricetulus griseus OX=10029 GN=Cpsf4 PE=3 SV=1 CANONICAL=A0A9J7FVH7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV13" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV13" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773929", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773929", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O19137-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 4", "gene_name": "CPSF4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPTKRTPQVIGVMQSQNSSAGSRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ", "length": 243 }, "evidence": [ { "id": "A0A9J7FVH7", "url": "https://omabrowser.org/oma/group/A0A9J7FVH7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95639-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 4", "gene_name": "CPSF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPAKQSNNPPLQRSSSLIQLTSQNSSPNQQRTPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ", "length": 269 }, "evidence": [ { "id": "A0A9J7FVH7", "url": "https://omabrowser.org/oma/group/A0A9J7FVH7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q55CA3-1", "protein_name": "CCCH-type zinc finger-containing protein", "gene_name": "cpsf4", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSELEVDILSLSLTFDFEAYFTDKTDGDGDDKDGSDICRFFLKGSCTKGSDCPYKHTKAERAVVCKHWLRGLCKKGELCEFLHEYDLQKMPECYFFSKHGECNNQECMYLHVNPEEKVRECPWYSRGFCKHGPKCRHKHIKKLLCENYYLGFCPEGPKCKYGHPKYELPKEEPEKKVNIQEQFEMEQQQQQQQQQQQFHHHQQQNQQFNGMGGNNNNNEFRPKQQFQQNQPFNKGGPMENGFNPNKPIICHKCGTPGHKSNACPNSEQFKQGNGPPGQQSYGGGGGGFKPQFNNGGNPPNLESVICKKCQQTGHYANKCPNKKVGGYQGFNNQNQPPQGGQQNMYYQQQPPQGGQPPPHYYQQQQQQQQQQY", "length": 372 }, "evidence": [ { "id": "A0A9J7FVH7", "url": "https://omabrowser.org/oma/group/A0A9J7FVH7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5FVR7-1", "protein_name": "Cleavage and polyadenylation specificity factor subunit 4", "gene_name": "Cpsf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMDKSGAAVCEFFLKAACGKGGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSKFGECSNKECPFLHIDPESKIKDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFELPMGTTEQPPLPQQTQPPTKRAPQVIGVMQSQNSSAGNRGPRPLEQVTCYKCGEKGHYANRCTKGHLAFLSGQ", "length": 243 }, "evidence": [ { "id": "A0A9J7FVH7", "url": "https://omabrowser.org/oma/group/A0A9J7FVH7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mRNA cleavage and polyadenylation specificity factor complex", "id": "GO:0005847", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005847", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA 3'-end processing", "id": "GO:0031124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031124", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FVH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 59, "start_aa": "Lys", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FVH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVH7" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 260, "start_aa": "Cys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 229, "end_pos": 231 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "A0A9J7FV21-1", "uniprot_ac": "A0A9J7FV21", "uniprot_id": "A0A9J7FV21_CRIGR", "mass": { "chemical_mass": 43816.0, "monoisotopic_mass": 43816.0 }, "refseq": { "ac": "XP_007641248", "name": "septin-5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641248" }, "gene_names": [ { "name": "Septin5", "type": "recommended", "evidence": [ { "id": "A0A9J7FV21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ] }, { "name": "Septin5", "type": "synonym", "evidence": [ { "id": "XP_007641248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641248" } ] } ], "protein_names": [ { "name": "Septin", "type": "recommended", "evidence": [ { "id": "A0A9J7FV21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21/entry#names_and_taxonomy" } ] }, { "name": "septin-5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007641248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641248" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 373 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613898.1) and transcript sequence (IACG01055331.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007641248", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641248" } ] }, { "annotation": "Filament-forming cytoskeletal GTPase.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21#function" }, { "database": "UniProtKB", "id": "PIRNR006698", "url": "https://www.uniprot.org/uniprotkb/PIRNR006698#function" }, { "database": "UniProtKB", "id": "A0A8C2MJF8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJF8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Septin5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21", "locus": {} } ], "crossref": [ { "id": "A0A9J7FV21", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FV21", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769765", "url": "https://www.ncbi.nlm.nih.gov/gene/100769765", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769765", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FV21", "url": "https://www.orthodb.org/?gene=A0A9J7FV21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007641248", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641248", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MJF8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MJF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV21-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV48-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV48-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLAAPQDRLVEQLLSPRTQAQRRLKDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERINQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNSECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQKMKQQMQDQ", "length": 378, "header": "tr|A0A9J7FV21-1|A0A9J7FV21_CRIGR Isoform 1 of Septin OS=Cricetulus griseus OX=10029 GN=Septin5 PE=3 SV=1 CANONICAL=A0A9J7FV21-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MJF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21/entry#A0A8C2MJF8-1", "sequence": { "sequence": "MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERINQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNSECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQKMKQQMQDQ", "length": 369, "header": "tr|A0A8C2MJF8-1|A0A8C2MJF8_CRIGR Computationally mapped isoform of Septin OS=Cricetulus griseus OX=10029 GN=Septin5 PE=3 SV=1 CANONICAL=A0A9J7FV21-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FV21-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21/entry#A0A9J7FV21-1", "sequence": { "sequence": "MDSLAAPQDRLVEQLLSPRTQAQRRLKDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERINQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNSECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQKMKQQMQDQ", "length": 378, "header": "tr|A0A9J7FV21-1|A0A9J7FV21_CRIGR Isoform 1 of Septin OS=Cricetulus griseus OX=10029 GN=Septin5 PE=3 SV=1 CANONICAL=A0A9J7FV21-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FV48-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21/entry#A0A9J7FV48-1", "sequence": { "sequence": "MVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERINQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNSECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKDRIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQKMKQQMQDQ", "length": 322, "header": "tr|A0A9J7FV48-1|A0A9J7FV48_CRIGR Computationally mapped isoform of Septin-5 isoform X4 OS=Cricetulus griseus OX=10029 GN=Septin5 PE=3 SV=1 CANONICAL=A0A9J7FV21-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 345, "start_aa": "Thr", "end_pos": 345, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr345", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769765", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ], "pmid": "" }, { "name": "synaptic vesicle", "id": "GO:0008021", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008021", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ], "pmid": "" }, { "name": "regulation of exocytosis", "id": "GO:0017157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017157", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FV21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV21" }, { "id": "PS51719", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51719" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Septin-type G", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 323, "start_aa": "Lys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 345 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FV35-1", "uniprot_ac": "A0A9J7FV35", "uniprot_id": "A0A9J7FV35_CRIGR", "mass": { "chemical_mass": 34488.0, "monoisotopic_mass": 34488.0 }, "refseq": { "ac": "XP_027269130", "name": "olfactory receptor 5AC1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269130" }, "gene_names": [ { "name": "LOC100774791", "type": "recommended", "evidence": [ { "id": "A0A9J7FV35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV35" } ] }, { "name": "LOC100774791", "type": "synonym", "evidence": [ { "id": "XP_027269130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269130" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7FV35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV35/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5AC1-like", "type": "synonym", "evidence": [ { "id": "XP_027269130", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269130" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269130" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV35", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV35" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100774791", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV35", "locus": {} } ], "crossref": [ { "id": "A0A9J7FV35", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FV35", "database": "AlphaFoldDB", "categories": [] }, { "id": "100774791", "url": "https://www.ncbi.nlm.nih.gov/gene/100774791", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774791", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774791", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FV35", "url": "https://www.orthodb.org/?gene=A0A9J7FV35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269130", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FV35", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV35-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV35-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGNRTLLTEFVLRGITDRPELQVPLFLVFFFIYVVTMVGNLGLIFLIWKDTHLHTPMYLFLGNLAFADACISTTVTPKMLMTFLNKNDIITLGECFAQYYFFCISATTEIFLLVAMAYDRYVAICNPLHYVVVMSKRLCTVLISMSYIIGFVNCGLNVGLLFRLTFCKSNIIDHFYCEILPLYTISCTDPSLNTLIIFICASSIQISTSVTIVVSYARVLFAVVNMKSKKGRQKAFFTCSAHLLSVSLFYGTLLFMYVSHGSGPGKQQDKIYSLFYTVVIPLLNPFIYSLRNKEVLGALKNVVK", "length": 305, "header": "tr|A0A9J7FV35-1|A0A9J7FV35_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100774791 PE=3 SV=1 CANONICAL=A0A9J7FV35-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FV35-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV35/entry#A0A9J7FV35-1", "sequence": { "sequence": "MEGNRTLLTEFVLRGITDRPELQVPLFLVFFFIYVVTMVGNLGLIFLIWKDTHLHTPMYLFLGNLAFADACISTTVTPKMLMTFLNKNDIITLGECFAQYYFFCISATTEIFLLVAMAYDRYVAICNPLHYVVVMSKRLCTVLISMSYIIGFVNCGLNVGLLFRLTFCKSNIIDHFYCEILPLYTISCTDPSLNTLIIFICASSIQISTSVTIVVSYARVLFAVVNMKSKKGRQKAFFTCSAHLLSVSLFYGTLLFMYVSHGSGPGKQQDKIYSLFYTVVIPLLNPFIYSLRNKEVLGALKNVVK", "length": 305, "header": "tr|A0A9J7FV35-1|A0A9J7FV35_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100774791 PE=3 SV=1 CANONICAL=A0A9J7FV35-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269146", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269146" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV45" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100768217", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV45", "locus": {} } ], "crossref": [ { "id": "A0A9J7FV45", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FV45", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768217", "url": "https://www.ncbi.nlm.nih.gov/gene/100768217", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768217", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768217", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FV45", "url": "https://www.orthodb.org/?gene=A0A9J7FV45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269146", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269146", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FV45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV45-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV45-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERKNVTLLTEFVLVGLTHQTQWEFPLFCVFLAMYLITIMGNFGLITLIWKDPHLHIPMYIFLSSLAFVDTWVSSTVSPKILVTLLFHNMKISLSECLTQFFSFAISATTECFLLTAMAYDRYVAICRPLLYPAIMTNRLCFWLIILSFVGGFLHALIHEIFLLRLNFCDSNIIHHFYCDIMPLLKISCSDPSINFLLVFILAGSIQVVTMVTVLVSYTCIIFTILQSRSFKGIKKAFSTCGAHLLSVSLYYGPLLFMYVRPASPQADDQDMMDSLFYTVIIPVLNPVIYSLRNKQVKDSVIKALKGNV", "length": 309, "header": "tr|A0A9J7FV45-1|A0A9J7FV45_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100768217 PE=3 SV=1 CANONICAL=A0A9J7FV45-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FV45-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV45/entry#A0A9J7FV45-1", "sequence": { "sequence": "MERKNVTLLTEFVLVGLTHQTQWEFPLFCVFLAMYLITIMGNFGLITLIWKDPHLHIPMYIFLSSLAFVDTWVSSTVSPKILVTLLFHNMKISLSECLTQFFSFAISATTECFLLTAMAYDRYVAICRPLLYPAIMTNRLCFWLIILSFVGGFLHALIHEIFLLRLNFCDSNIIHHFYCDIMPLLKISCSDPSINFLLVFILAGSIQVVTMVTVLVSYTCIIFTILQSRSFKGIKKAFSTCGAHLLSVSLYYGPLLFMYVRPASPQADDQDMMDSLFYTVIIPVLNPVIYSLRNKQVKDSVIKALKGNV", "length": 309, "header": "tr|A0A9J7FV45-1|A0A9J7FV45_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100768217 PE=3 SV=1 CANONICAL=A0A9J7FV45-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation" ] }, { "id": "IPR000403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037706", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037706", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046803", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046803", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770748", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770748", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FV80", "url": "https://www.orthodb.org/?gene=A0A9J7FV80", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11139:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11139:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02259", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02259", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02260", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02260", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08163", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08163", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20500", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20500", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20502", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20502", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269233", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV80-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQAGAGVMEDAGAGIRGWLLQLQEFLSAADRCSAAGASYQLIRGLGQECVLSTSSAVLALQVSLVFSREFGLLVFIRKSLNIDEFRDCREEALKFLYVFLEKIDQKVMHYSLDIKNTCTSVYTKDRTAKCKISALDLLIKLLKILRSSRLMDEFKIGELFNKFYGELASKTKLPDTVLEKVYELLGVLGEVHPSEMINHSENLFRAFLGELKTQMTSTVREPKFPVLAGCLKGLSSLLCNFTKSMEEDPQTSKEIFGFALKAIRPQIEMKRYAVPLAGLRLFTLHASQFTACLLDNYVTLFEVLSKWCSHTNMELKKAAHSALESFLKQISFTVAEDAELHKSQLRYFMEQFYKIIRNADSNNKELSIAIRGYGLFAGPCKAINAKDVDFMYVELIQRCKQMFLTQTEATEDHVYQMPSFLQSIASVLLYLDTVPEVHTPVLEHLMVVQIDSFPQYSPKMQLMCCKAIVKVFLALAEKGPVHWNFISTVVHQGLIRICSKPVVLQKDVESKSDNQWASGEVRTGKWKVPTYKDYVDLFRHLLSCDQMMDFILADETFLFVNSSLQSLNHLLYDEFIRSVLKIVGKLDLTLEKQTVEEHEDGSTTGGWVIPTSDPAGNLHPAKPKDFSAFINLVEFCREILPKKQIRFFEPWVYSFAYELILQSTRLPLISGFYKLLSIAVKNARKIKYFEGVSPKSLKHSPEDPEKYSCFALFAKFGKEVSVKMKQYKDELLASCITFVLSLPHDIIELDVRTYVPALQMAFKLGLSHMPLAEIGLHALEEWSVHIDKSIMQPYYKDILPCLDGYLKTSILSDETKSHWEVSALSRAAQKGFNKNVLKHLKRTTNILPDEALSLEEVRIRVVQILGSLGGQINKNLLTASSRERMKKYVAWDREKRLSFAVPFREMKPVIYLDVFLPRVTELALSASDRQTKVAACELLHSMVVFMLGKATHMPEGQGCPPMYQLYKHTFPALLQLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLETILDGIVDPVDSTLRDFCGCCIREFLKWSIKQTTPQQQEKSPVNSKSLFKRLYSLALHPNAFKRLGAALAFNHIYKEFREEESLVEQFVFEALVTYMESLALAHADEKSLGTIQQCCDAIDHLSRIIEKKHVSLNKPKERRRPRGFSSMASCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPGNKSPSLWLKDLIKTEAISFLINTFEGGDSSCDQPAGILAQPTLFHLQGPISLRAVLQWLDMLLAALECYNTFIEKKTVEIQEVLGTKTQSSLLKSVAFFLESIATHDARAVEQRFGTGVTTGPPSLQEEEKYNYSKCTVLVRIVDFTTTLLNASPEVFKLLEDLCNTNLMKVLVKMLCEPTSLGFNVGDVQVINNLPSICVNLLKALKKSPYRDLLETHLKEKLTVQSVEELCAISFCSSDARRERTRLLSILSACKQLHRAGFSHVISPSQSTALTDSIGMRLLSLVYNGIAPAEERQCLQSLDPSCKSLANGLLELAFAYEGLCDHLVSLLLNSAMLSTKYLGSSQRNISFSHGEYFYTLFSEIINSELLKNLDTAVSELMKSSADNPKMVSTVLNGMLDQSFKDRAVQKHHGLKLAAAILQNWRKCDSWWAIDSPSESKMTVLSLLAKMLQIDSALSFDTNHSSFPEIFTTYASLLADTELGLHLKGQAIILLPFFTSLTEDRLENLKHILEKLIVSNFPMKSDEFPPDSLKYNNYVDCMKKFLDALELSQSPMLLQLMTDILCREQQHIMEELFQTTFKRIAKRSPHVTQLNLLQSVYTMFRKDDLPSNVTRQAFVDRSLLTLLWHCDLDTLKEFFSRIVVDAIDVLKSRFTKVNEFTFDTQITKKMCYYKMLAVMYSRLSKDDVHSKESKINQAFHGSCITEGNELTKILLKSCHDAFTENMAGESQLLEKRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLFIFENLIDLKRCYAFPIEVEVPMERKKKYIEIRKEARDAANGASGSPHYMSSLSYLADSSLSEEMSQFDFSTGVQSYSYSSQDHKPTTGNFQRREHQDPMTQGDILELEMDELNQHECMATMTALIKHMQRNLITPSGEEDSKPKDLPPWMKFLHDKLGNPSVSLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAVSQNNGEGIHYMVVEIVATVLSWTGLATPKGVPKDEVLANRLLHFLMEHVFHPKKAVFRHNLEIIKTLVECWKECLSIPYRLIFEKFSHKDPNSKDNSVGIQLLGIVIANDLPPYDPKCDVASTRYFEALVNNMFFVKYKEVYAAAAEVLGLILQHVTERKQVIAESVCELVVKQLKQHQNTMEDKFIVCLNKVVKGFPPLADSFLNAVFFLLPKFHGVMKTLCLEVVLCRAETTTDLYLQLKSKDFLQVMRHRDDERQKVCLDIVYKMMAELKPVELRELLNPVMEFVSHPSPACREQMYNILMWIHDNYRDPESQMDQDSQEIFKLAKDVLIQGLVDENPGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTRMSPDYLNPIFEHPLSECEFQEYTIDPDWRFRSTVLTPMFIETQASPSILHTQTQEGSLSDRRQKSGQVRATQQQYDFTPTQTIVERSSFDWLTGSSIDPLADHTLVPSESSSSSLLFAHKRSEKSQRISWKSVGPDFGIKKLGLPGDEVDNQAKSGTYNRAEILRLRRRFLKDREKLSLLYAKKGLVEQKLEKDIKSELKTKQNAQVVLYRSYRYGDLPDIQILHSSLITPLQAVAQKDPIIAKQLFSSLFSGILKEMNKFKATSEKNIIIQNLLQDFNRFLNTTFLFFPPFVSCIQEICCQYPGLLSLDPAAVRVGCLASLQQPGGIRLLEEALLRLVPDEPPIKRVRGKTCWPPDVLRWMELAKLYRSIGEYDILRGIFSSELGTKQDTRNALLAEARSDYSQAAKLYNEALNKQEWVDGEPTEAEKEFWELASLDCYNNLSEWKALEYCSTTSIGSENPLDLSKMWSELFYQEMYLPYVIRSKLKLLLNGEGNQSLLTFVDEAMHKELQQTVLELHYSQELSLLYILQDDIDRATYYIKNGIQIFMQNYSSIDVLLHRSRLAKLQSVQTLAEIEEFLNFISKHGDLSSPGPLRRLLKTWTSRYPDAVTDPMHIWDDIITNRCFFLSKIEERLTASSGDLSMSVDEDEDSLDRREVHEPKEDVHSMIQSCRFTMKMKMIESAWKQKNFSLAMKLLKELHKDSKTRETWQVQWTQSYCQLSHSKSRTQSSREQVLTALKTIPLLDDSNMSSYFNKNIQASCNQNILLGTTFRFMADALNREPACLSDLEETKAKSVLALSGSDAESTEKVISGLYQRAFHYFSKAVQLAEEEDLLSCWGHEAAAEQAHAYMTLVGFCDQQLRKVEESASNTSQKRCAELEAYPALVVEKLLRALKLNSSEARLKFPRLLQIIEQYSEETLNIMTKEISSIPCWQFIGWISHMVALLDKEEAIAVQHTVEEIADNYPQAIIYPFIISSESYSFKQTSSGCKNKAFVERIKSKLDQVREIQDFINALDQLSNPDMIFKDWIDDTKVELEKNPVNKNNIEKLYQRMHTALGDLEAPWLGPFRKRFIQAFGKEFDKSFGNNGSKLPTMKFGDFCNITDSLLRRMRKDSKPPGNLKEYSPKMSEFKGNELEIPGQYDGRGKPLPEYHVRISGFDERVKVMVSLRKPKRIVIRGHDEKEYPFLVKGGEDLRQDQRIEQLFEVMNAILAQDAACSQRNMQLRTYRVMPMTCRLGLIEWIENTTTLKDLLLSSMSKEEKEAYNSDPKAPIREYKDWLKQITKKSDAGAYLLMYKGANRTETVTAFRKRENKVPADLLKRAFVKMSTNPEAFLALRSHFASSHALLCISHWLLGIGDRHLNNFMVAMETGSVIGIDFGHAFGSATQCLPVPELMPFRLTRQFVSLMLPMKETGLVCAVMVYALRAFRSCADLLTDTMDVFVKEPFFYWKSDEQKMLKKGGSWIQEINVTEENWYPQQKIRYAKRKLAGANPAVITCDELRLGHESSPAFGSYTAVARGHKNHNIRAQEPESGLSEETQVKCLVDQATDPNILGRTWEGWEPWM", "length": 4135, "header": "tr|A0A9J7FV80-1|A0A9J7FV80_CRIGR Isoform 1 of DNA-dependent protein kinase catalytic subunit OS=Cricetulus griseus OX=10029 GN=Prkdc PE=3 SV=1 CANONICAL=A0A9J7FV80-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FV80-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80/entry#A0A9J7FV80-1", "sequence": { "sequence": "MRQAGAGVMEDAGAGIRGWLLQLQEFLSAADRCSAAGASYQLIRGLGQECVLSTSSAVLALQVSLVFSREFGLLVFIRKSLNIDEFRDCREEALKFLYVFLEKIDQKVMHYSLDIKNTCTSVYTKDRTAKCKISALDLLIKLLKILRSSRLMDEFKIGELFNKFYGELASKTKLPDTVLEKVYELLGVLGEVHPSEMINHSENLFRAFLGELKTQMTSTVREPKFPVLAGCLKGLSSLLCNFTKSMEEDPQTSKEIFGFALKAIRPQIEMKRYAVPLAGLRLFTLHASQFTACLLDNYVTLFEVLSKWCSHTNMELKKAAHSALESFLKQISFTVAEDAELHKSQLRYFMEQFYKIIRNADSNNKELSIAIRGYGLFAGPCKAINAKDVDFMYVELIQRCKQMFLTQTEATEDHVYQMPSFLQSIASVLLYLDTVPEVHTPVLEHLMVVQIDSFPQYSPKMQLMCCKAIVKVFLALAEKGPVHWNFISTVVHQGLIRICSKPVVLQKDVESKSDNQWASGEVRTGKWKVPTYKDYVDLFRHLLSCDQMMDFILADETFLFVNSSLQSLNHLLYDEFIRSVLKIVGKLDLTLEKQTVEEHEDGSTTGGWVIPTSDPAGNLHPAKPKDFSAFINLVEFCREILPKKQIRFFEPWVYSFAYELILQSTRLPLISGFYKLLSIAVKNARKIKYFEGVSPKSLKHSPEDPEKYSCFALFAKFGKEVSVKMKQYKDELLASCITFVLSLPHDIIELDVRTYVPALQMAFKLGLSHMPLAEIGLHALEEWSVHIDKSIMQPYYKDILPCLDGYLKTSILSDETKSHWEVSALSRAAQKGFNKNVLKHLKRTTNILPDEALSLEEVRIRVVQILGSLGGQINKNLLTASSRERMKKYVAWDREKRLSFAVPFREMKPVIYLDVFLPRVTELALSASDRQTKVAACELLHSMVVFMLGKATHMPEGQGCPPMYQLYKHTFPALLQLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLETILDGIVDPVDSTLRDFCGCCIREFLKWSIKQTTPQQQEKSPVNSKSLFKRLYSLALHPNAFKRLGAALAFNHIYKEFREEESLVEQFVFEALVTYMESLALAHADEKSLGTIQQCCDAIDHLSRIIEKKHVSLNKPKERRRPRGFSSMASCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPGNKSPSLWLKDLIKTEAISFLINTFEGGDSSCDQPAGILAQPTLFHLQGPISLRAVLQWLDMLLAALECYNTFIEKKTVEIQEVLGTKTQSSLLKSVAFFLESIATHDARAVEQRFGTGVTTGPPSLQEEEKYNYSKCTVLVRIVDFTTTLLNASPEVFKLLEDLCNTNLMKVLVKMLCEPTSLGFNVGDVQVINNLPSICVNLLKALKKSPYRDLLETHLKEKLTVQSVEELCAISFCSSDARRERTRLLSILSACKQLHRAGFSHVISPSQSTALTDSIGMRLLSLVYNGIAPAEERQCLQSLDPSCKSLANGLLELAFAYEGLCDHLVSLLLNSAMLSTKYLGSSQRNISFSHGEYFYTLFSEIINSELLKNLDTAVSELMKSSADNPKMVSTVLNGMLDQSFKDRAVQKHHGLKLAAAILQNWRKCDSWWAIDSPSESKMTVLSLLAKMLQIDSALSFDTNHSSFPEIFTTYASLLADTELGLHLKGQAIILLPFFTSLTEDRLENLKHILEKLIVSNFPMKSDEFPPDSLKYNNYVDCMKKFLDALELSQSPMLLQLMTDILCREQQHIMEELFQTTFKRIAKRSPHVTQLNLLQSVYTMFRKDDLPSNVTRQAFVDRSLLTLLWHCDLDTLKEFFSRIVVDAIDVLKSRFTKVNEFTFDTQITKKMCYYKMLAVMYSRLSKDDVHSKESKINQAFHGSCITEGNELTKILLKSCHDAFTENMAGESQLLEKRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLFIFENLIDLKRCYAFPIEVEVPMERKKKYIEIRKEARDAANGASGSPHYMSSLSYLADSSLSEEMSQFDFSTGVQSYSYSSQDHKPTTGNFQRREHQDPMTQGDILELEMDELNQHECMATMTALIKHMQRNLITPSGEEDSKPKDLPPWMKFLHDKLGNPSVSLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAVSQNNGEGIHYMVVEIVATVLSWTGLATPKGVPKDEVLANRLLHFLMEHVFHPKKAVFRHNLEIIKTLVECWKECLSIPYRLIFEKFSHKDPNSKDNSVGIQLLGIVIANDLPPYDPKCDVASTRYFEALVNNMFFVKYKEVYAAAAEVLGLILQHVTERKQVIAESVCELVVKQLKQHQNTMEDKFIVCLNKVVKGFPPLADSFLNAVFFLLPKFHGVMKTLCLEVVLCRAETTTDLYLQLKSKDFLQVMRHRDDERQKVCLDIVYKMMAELKPVELRELLNPVMEFVSHPSPACREQMYNILMWIHDNYRDPESQMDQDSQEIFKLAKDVLIQGLVDENPGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTRMSPDYLNPIFEHPLSECEFQEYTIDPDWRFRSTVLTPMFIETQASPSILHTQTQEGSLSDRRQKSGQVRATQQQYDFTPTQTIVERSSFDWLTGSSIDPLADHTLVPSESSSSSLLFAHKRSEKSQRISWKSVGPDFGIKKLGLPGDEVDNQAKSGTYNRAEILRLRRRFLKDREKLSLLYAKKGLVEQKLEKDIKSELKTKQNAQVVLYRSYRYGDLPDIQILHSSLITPLQAVAQKDPIIAKQLFSSLFSGILKEMNKFKATSEKNIIIQNLLQDFNRFLNTTFLFFPPFVSCIQEICCQYPGLLSLDPAAVRVGCLASLQQPGGIRLLEEALLRLVPDEPPIKRVRGKTCWPPDVLRWMELAKLYRSIGEYDILRGIFSSELGTKQDTRNALLAEARSDYSQAAKLYNEALNKQEWVDGEPTEAEKEFWELASLDCYNNLSEWKALEYCSTTSIGSENPLDLSKMWSELFYQEMYLPYVIRSKLKLLLNGEGNQSLLTFVDEAMHKELQQTVLELHYSQELSLLYILQDDIDRATYYIKNGIQIFMQNYSSIDVLLHRSRLAKLQSVQTLAEIEEFLNFISKHGDLSSPGPLRRLLKTWTSRYPDAVTDPMHIWDDIITNRCFFLSKIEERLTASSGDLSMSVDEDEDSLDRREVHEPKEDVHSMIQSCRFTMKMKMIESAWKQKNFSLAMKLLKELHKDSKTRETWQVQWTQSYCQLSHSKSRTQSSREQVLTALKTIPLLDDSNMSSYFNKNIQASCNQNILLGTTFRFMADALNREPACLSDLEETKAKSVLALSGSDAESTEKVISGLYQRAFHYFSKAVQLAEEEDLLSCWGHEAAAEQAHAYMTLVGFCDQQLRKVEESASNTSQKRCAELEAYPALVVEKLLRALKLNSSEARLKFPRLLQIIEQYSEETLNIMTKEISSIPCWQFIGWISHMVALLDKEEAIAVQHTVEEIADNYPQAIIYPFIISSESYSFKQTSSGCKNKAFVERIKSKLDQVREIQDFINALDQLSNPDMIFKDWIDDTKVELEKNPVNKNNIEKLYQRMHTALGDLEAPWLGPFRKRFIQAFGKEFDKSFGNNGSKLPTMKFGDFCNITDSLLRRMRKDSKPPGNLKEYSPKMSEFKGNELEIPGQYDGRGKPLPEYHVRISGFDERVKVMVSLRKPKRIVIRGHDEKEYPFLVKGGEDLRQDQRIEQLFEVMNAILAQDAACSQRNMQLRTYRVMPMTCRLGLIEWIENTTTLKDLLLSSMSKEEKEAYNSDPKAPIREYKDWLKQITKKSDAGAYLLMYKGANRTETVTAFRKRENKVPADLLKRAFVKMSTNPEAFLALRSHFASSHALLCISHWLLGIGDRHLNNFMVAMETGSVIGIDFGHAFGSATQCLPVPELMPFRLTRQFVSLMLPMKETGLVCAVMVYALRAFRSCADLLTDTMDVFVKEPFFYWKSDEQKMLKKGGSWIQEINVTEENWYPQQKIRYAKRKLAGANPAVITCDELRLGHESSPAFGSYTAVARGHKNHNIRAQEPESGLSEETQVKCLVDQATDPNILGRTWEGWEPWM", "length": 4135, "header": "tr|A0A9J7FV80-1|A0A9J7FV80_CRIGR Isoform 1 of DNA-dependent protein kinase catalytic subunit OS=Cricetulus griseus OX=10029 GN=Prkdc PE=3 SV=1 CANONICAL=A0A9J7FV80-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80/entry#A0A9J7FWN6-1", "sequence": { "sequence": "MRQAGAGVMEDAGAGIRGWLLQLQEFLSAADRCSAAGASYQLIRGLGQECVLSTSSAVLALQVSLVFSREFGLLVFIRKSLNIDEFRDCREEALKFLYVFLEKIDQKVMHYSLDIKNTCTSVYTKDRTAKCKISALDLLIKLLKILRSSRLMDEFKIGELFNKFYGELASKTKLPDTVLEKVYELLGVLGEVHPSEMINHSENLFRAFLGELKTQMTSTVREPKFPVLAGCLKGLSSLLCNFTKSMEEDPQTSKEIFGFALKAIRPQIEMKRYAVPLAGLRLFTLHASQFTACLLDNYVTLFEVLSKWCSHTNMELKKAAHSALESFLKQISFTVAEDAELHKSQLRYFMEQFYKIIRNADSNNKELSIAIRGYGLFAGPCKAINAKDVDFMYVELIQRCKQMFLTQTEATEDHVYQMPSFLQSIASVLLYLDTVPEVHTPVLEHLMVVQIDSFPQYSPKMQLMCCKAIVKVFLALAEKGPVHWNFISTVVHQGLIRICSKPVVLQKDVESKSDNQWASGEVRTGKWKVPTYKDYVDLFRHLLSCDQMMDFILADETFLFVNSSLQSLNHLLYDEFIRSVLKIVGKLDLTLEKQTVEEHEDGSTTGGWVIPTSDPAGNLHPAKPKDFSAFINLVEFCREILPKKQIRFFEPWVYSFAYELILQSTRLPLISGFYKLLSIAVKNARKIKYFEGVSPKSLKHSPEDPEKYSCFALFAKFGKEVSVKMKQYKDELLASCITFVLSLPHDIIELDVRTYVPALQMAFKLGLSHMPLAEIGLHALEEWSVHIDKSIMQPYYKDILPCLDGYLKTSILSDETKSHWEVSALSRAAQKGFNKNVLKHLKRTTNILPDEALSLEEVRIRVVQILGSLGGQINKNLLTASSRERMKKYVAWDREKRLSFAVPFREMKPVIYLDVFLPRVTELALSASDRQTKVAACELLHSMVVFMLGKATHMPEGQGCPPMYQLYKHTFPALLQLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLETILDGIVDPVDSTLRDFCGCCIREFLKWSIKQTTPQQQEKSPVNSKSLFKRLYSLALHPNAFKRLGAALAFNHIYKEFREEESLVEQFVFEALVTYMESLALAHADEKSLGTIQQCCDAIDHLSRIIEKKHVSLNKPKERRRPRGFSSMASCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPGNKSPSLWLKDLIKTEAISFLINTFEGGDSSCDQPAGILAQPTLFHLQGPISLRAVLQWLDMLLAALECYNTFIEKKTVEIQEVLGTKTQSSLLKSVAFFLESIATHDARAVEQRFGTGVTTGPPSLQEEEKYNYSKCTVLVRIVDFTTTLLNASPEVFKLLEDLCNTNLMKVLVKMLCEPTSLGFNVGDVQVINNLPSICVNLLKALKKSPYRDLLETHLKEKLTVQSVEELCAISFCSSDARRERTRLLSILSACKQLHRAGFSHVISPSQSTALTDSIGMRLLSLVYNGIAPAEERQCLQSLDPSCKSLANGLLELAFAYEGLCDHLVSLLLNSAMLSTKYLGSSQRNISFSHGEYFYTLFSEIINSELLKNLDTAVSELMKSSADNPKMVSTVLNGMLDQSFKDRAVQKHHGLKLAAAILQNWRKCDSWWAIDSPSESKMTVLSLLAKMLQIDSALSFDTNHSSFPEIFTTYASLLADTELGLHLKGQAIILLPFFTSLTEDRLENLKHILEKLIVSNFPMKSDEFPPDSLKYNNYVDCMKKFLDALELSQSPMLLQLMTDILCREQQHIMEELFQTTFKRIAKRSPHVTQLNLLQSVYTMFRKDDLPSNVTRQAFVDRSLLTLLWHCDLDTLKEFFSRIVVDAIDVLKSRFTKVNEFTFDTQITKKMCYYKMLAVMYSRLSKDDVHSKESKINQAFHGSCITEGNELTKILLKSCHDAFTENMAGESQLLEKRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLFIFENLIDLKRCYAFPIEVEVPMERKKKYIEIRKEARDAANGASGSPHYMSSLSYLADSSLSEEMSQFDFSTGVQSYSYSSQDHKPTTGNFQRREHQDPMTQGDILELEMDELNQHECMATMTALIKHMQRNLITPSGEEDSKPKDLPPWMKFLHDKLGNPSVSLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAVSQNNGEGIHYMVVEIVATVLSWTGLATPKGVPKDEVLANRLLHFLMEHVFHPKKAVFRHNLEIIKTLVECWKECLSIPYRLIFEKFSHKDPNSKDNSVGIQLLGIVIANDLPPYDPKCDVASTRYFEALVNNMFFVKYKEVYAAAAEVLGLILQHVTERKQVIAESVCELVVKQLKQHQNTMEDKFIVCLNKVVKGFPPLADSFLNAVFFLLPKFHGVMKTLCLEVVLCRAETTTDLYLQLKSKDFLQVMRHRDDERQKVCLDIVYKMMAELKPVELRELLNPVMEFVSHPSPACREQMYNILMWIHDNYRDPESQMDQDSQEIFKLAKDVLIQGLVDENPGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTRMSPDYLNPIFEHPLSECEFQEYTIDPDWRFRSTVLTPMFIETQASPSILHTQTQEGSLSDRRQKSGQVRATQQQYDFTPTQTIVERSSFDWLTGSSIDPLADHTLVPSESSSSSLLFAHKRSEKSQRISWKSVGPDFGIKKLGLPGDEVDNQAKSGTYNRAEILRLRRRFLKDREKLSLLYAKKGLVEQKLEKDIKSELKTKQNAQVVLYRSYRYGDLPDIQILHSSLITPLQAVAQKDPIIAKQLFSSLFSGILKEMNKFKATSEKNIIIQNLLQDFNRFLNTTFLFFPPFVSCIQEICCQYPGLLSLDPAAVRVGCLASLQQPGGIRLLEEALLRLVPDEPPIKRVRGKTCWPPDVLRWMELAKLYRSIGEYDILRGIFSSELGTKQDTRNALLAEARSDYSQAAKLYNEALNKQEWVDGEPTEAEKEFWELASLDCYNNLSEWKALEYCSTTSIGSENPLDLSKMWSELFYQEMYLPYVIRSKLKLLLNGEGNQSLLTFVDEAMHKELQQTVLELHYSQELSLLYILQDDIDRATYYIKNGIQIFMQNYSSIDVLLHRSRLAKLQSVQTLAEIEEFLNFISKHGDLSSPGPLRRLLKTWTSRYPDAVTDPMHIWDDIITNRCFFLSKIEERLTASSGDLSMSVDEDEDSLDRREVHEPKEDVHSMIQSCRFTMKMKMIESAWKQKNFSLAMKLLKELHKDSKTRETWQVQWTQSYCQLSHSKSRTQSSREQVLTALKTIPLLDDSNMSSYFNKNIQASCNQNILLGTTFRFMADALNREPACLSDLEETKAKSVLALSGSDAESTEKVISGLYQRAFHYFSKAVQLAEEEDLLSCWGHEAAAEQAHAYMTLVGFCDQQLRKVEESASNTSQKRCAELEAYPALVVEKLLRALKLNSSEARLKFPRLLQIIEQYSEETLNIMTKEFF", "length": 3499, "header": "tr|A0A9J7FWN6-1|A0A9J7FWN6_CRIGR Computationally mapped isoform of DNA-dependent protein kinase catalytic subunit isoform X2 OS=Cricetulus griseus OX=10029 GN=Prkdc PE=4 SV=1 CANONICAL=A0A9J7FV80-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770748", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770748", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" }, { "name": "DNA-dependent protein kinase activity", "id": "GO:0004677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" }, { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "telomere maintenance", "id": "GO:0000723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" }, { "name": "ribosome biogenesis", "id": "GO:0042254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042254", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:0008630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008630", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" }, { "name": "immunoglobulin V(D)J recombination", "id": "GO:0033152", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033152", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" }, { "name": "positive regulation of biosynthetic process", "id": "GO:0009891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009891", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1205, "end_pos": 1207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1337, "end_pos": 1339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1356, "end_pos": 1358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1554, "end_pos": 1556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1668, "end_pos": 1670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1817, "end_pos": 1819, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2853, "end_pos": 2855, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3012, "end_pos": 3014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3066, "end_pos": 3068, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3121, "end_pos": 3123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3259, "end_pos": 3261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3319, "end_pos": 3321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3441, "end_pos": 3443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3468, "end_pos": 3470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3658, "end_pos": 3660, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3672, "end_pos": 3674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3815, "end_pos": 3817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3870, "end_pos": 3872, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4039, "end_pos": 4041, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FV80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV80" }, { "id": "PS51189", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51189" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAT", "eco_id": "ECO_0000259", "start_pos": 2914, "end_pos": 3550, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FV80", "database": "UniProtKB", 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF75", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF75", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269250", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269250", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FV89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV89-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGGRRRPREVDMGTGSSPPLGGFLRCWGAASQGNTWMPCYWKESPGILSSKRNFSCFHVCSGLVSFEDVAVDFTWQEWQELDAAQRTLYRDVMLENYKSLVWLGYCLDKPELISKLEQGLVPWSSAEATEQCQPDVHKWSALAETRQKAQEKYLGQLEITKRNTSNEDMIEVEKTFDVGSNFISDMNMKNDFYSRMLHQELITPWQDVPLPNEPDERQVTEVTQDLNGTQEVLSYPDHFTQHSKEQCSECHFQCFGPVETYHQKAVLTPKKFHVQETSRKLSNCEKSLDEVAFPTQYMTQLGQQALGWNTCHKMYPRKTELSNHDNMHMEEKGYKCDYEKLILNKSYLTKYQEAYSGKEPHGHKENIQFFCVDAELQTVDQKTPREKQIYECKVSGQTFYHGSQHINHQRSHTCEKPCECEEDRKAIDDKSTLTQHQRLHTDDKSCECRECSQASYHNSLVSQYQRAHTDEQQNECKELMKIYFYISSLTQHHTPTLEKPYGCNDCMKTFSHKSQLTRHQRTHTGEKPHECKECRKAFCHKSHLTRHQGIHAPEKPYECKECQKAFYLKSQLTQHQRTHTGEKPYECKECRKAFFRNSHLTQHQKIHTGEKPHKCKECGNAFARKSHLTQHQKTHTGERPYECKDCGKTFSRKSQVIQHETTHTGEKPYECKECRKTFYLKAYLTRHQVIHKPEKPFECKRCGKTFSRKSYLTRHQKTHRGEKPNLGEKL", "length": 731, "header": "tr|A0A9J7FV89-1|A0A9J7FV89_CRIGR Isoform 1 of Zinc finger protein 345 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100768540 PE=3 SV=1 CANONICAL=A0A9J7FV89-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FV89-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89/entry#A0A9J7FV89-1", "sequence": { "sequence": "MVGGRRRPREVDMGTGSSPPLGGFLRCWGAASQGNTWMPCYWKESPGILSSKRNFSCFHVCSGLVSFEDVAVDFTWQEWQELDAAQRTLYRDVMLENYKSLVWLGYCLDKPELISKLEQGLVPWSSAEATEQCQPDVHKWSALAETRQKAQEKYLGQLEITKRNTSNEDMIEVEKTFDVGSNFISDMNMKNDFYSRMLHQELITPWQDVPLPNEPDERQVTEVTQDLNGTQEVLSYPDHFTQHSKEQCSECHFQCFGPVETYHQKAVLTPKKFHVQETSRKLSNCEKSLDEVAFPTQYMTQLGQQALGWNTCHKMYPRKTELSNHDNMHMEEKGYKCDYEKLILNKSYLTKYQEAYSGKEPHGHKENIQFFCVDAELQTVDQKTPREKQIYECKVSGQTFYHGSQHINHQRSHTCEKPCECEEDRKAIDDKSTLTQHQRLHTDDKSCECRECSQASYHNSLVSQYQRAHTDEQQNECKELMKIYFYISSLTQHHTPTLEKPYGCNDCMKTFSHKSQLTRHQRTHTGEKPHECKECRKAFCHKSHLTRHQGIHAPEKPYECKECQKAFYLKSQLTQHQRTHTGEKPYECKECRKAFFRNSHLTQHQKIHTGEKPHKCKECGNAFARKSHLTQHQKTHTGERPYECKDCGKTFSRKSQVIQHETTHTGEKPYECKECRKTFYLKAYLTRHQVIHKPEKPFECKRCGKTFSRKSYLTRHQKTHRGEKPNLGEKL", "length": 731, "header": "tr|A0A9J7FV89-1|A0A9J7FV89_CRIGR Isoform 1 of Zinc finger protein 345 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100768540 PE=3 SV=1 CANONICAL=A0A9J7FV89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89/entry#A0A9J7FWP6-1", "sequence": { "sequence": "MVGGRRRPREVDMGLVSFEDVAVDFTWQEWQELDAAQRTLYRDVMLENYKSLVWLGYCLDKPELISKLEQGLVPWSSAEATEQCQPDVHKWSALAETRQKAQEKYLGQLEITKRNTSNEDMIEVEKTFDVGSNFISDMNMKNDFYSRMLHQELITPWQDVPLPNEPDERQVTEVTQDLNGTQEVLSYPDHFTQHSKEQCSECHFQCFGPVETYHQKAVLTPKKFHVQETSRKLSNCEKSLDEVAFPTQYMTQLGQQALGWNTCHKMYPRKTELSNHDNMHMEEKGYKCDYEKLILNKSYLTKYQEAYSGKEPHGHKENIQFFCVDAELQTVDQKTPREKQIYECKVSGQTFYHGSQHINHQRSHTCEKPCECEEDRKAIDDKSTLTQHQRLHTDDKSCECRECSQASYHNSLVSQYQRAHTDEQQNECKELMKIYFYISSLTQHHTPTLEKPYGCNDCMKTFSHKSQLTRHQRTHTGEKPHECKECRKAFCHKSHLTRHQGIHAPEKPYECKECQKAFYLKSQLTQHQRTHTGEKPYECKECRKAFFRNSHLTQHQKIHTGEKPHKCKECGNAFARKSHLTQHQKTHTGERPYECKDCGKTFSRKSQVIQHETTHTGEKPYECKECRKTFYLKAYLTRHQVIHKPEKPFECKRCGKTFSRKSYLTRHQKTHRGEKPNLGEKL", "length": 682, "header": "tr|A0A9J7FWP6-1|A0A9J7FWP6_CRIGR Computationally mapped isoform of Zinc finger protein 883 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100768540 PE=3 SV=1 CANONICAL=A0A9J7FV89-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768540", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768540", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FV89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 391, "end_pos": 418, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FV89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV89" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 136, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FV92-1", "uniprot_ac": "A0A9J7FV92", "uniprot_id": "A0A9J7FV92_CRIGR", "mass": { "chemical_mass": 156976.0, "monoisotopic_mass": 156976.0 }, "refseq": { "ac": "XP_027265894", "name": "ubiquitin carboxyl-terminal hydrolase 47 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265894" }, "gene_names": [ { "name": "Usp47", "type": "recommended", "evidence": [ { "id": "A0A9J7FV92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92" } ] }, { "name": "Usp47", "type": "synonym", "evidence": [ { "id": "XP_027265894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265894" } ] } ], "protein_names": [ { "name": "Ubiquitin carboxyl-terminal hydrolase 47", "type": "recommended", "evidence": [ { "id": "A0A9J7FV92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "A0A9J7FV92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92/entry#names_and_taxonomy" } ] }, { "name": "Deubiquitinating enzyme 47", "type": "synonym", "evidence": [ { "id": "A0A9J7FV92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin thioesterase 47", "type": "synonym", "evidence": [ { "id": "A0A9J7FV92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-specific-processing protease 47", "type": "synonym", "evidence": [ { "id": "A0A9J7FV92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 47 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027265894", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265894" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265894" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Usp47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92", "locus": {} } ], "crossref": [ { "id": "cd02659", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02659", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766617", "url": "https://www.ncbi.nlm.nih.gov/gene/100766617", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766617", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766617", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FV92", "url": "https://www.orthodb.org/?gene=A0A9J7FV92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF702", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF702", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25985", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25985", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265894", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265894", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FV92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWA4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6W0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6W0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6W0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPGEENQLVPKEIENAAEEPRVLCIIQDTTNSKTVNERITLNLPASTPVRKLFEDVANKVGYVNGTFDLAWGNGVNTADTVPLDHTNDKSLLEANFEPGKKNFLHLTDKDGEQPQMMLDDTSNVDDSMHDRFIGPLPREGSVASTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMSFPEELDMSTFIDIEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSTDDAVDEGICLESSSGTEKISKPGLEKVEMAMTDQRKGSFQVQLGEPNSLMYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPTRNAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIERNTCKIKLFCLHPVKQVMMENKLEVHKDKTLKEAVEMAYKMMDLEEVIPLDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMFDLLLETRKPDQVFQSYKPGEVMVKVHVVDLKAETVAAPITVRAYLNQTVTEFKQLISKATHLPSESMRIVLERCYNDLRLLSVPSKTLKAEGFFRSNKVFVESSETLDHQAAFTDSHLWKLLDRHANTIRLFVLLPEQSPGSYSKRTAYQKAGGDSSNVDDDCERVKGPSGNLKSVDAILEESTEKLKSLSLQQQQDGDNGDSSKSTETSDFENIESPLNERGSSTSVDNRELEQHIQTSDPENFQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADSAQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKADPYAADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFVGVLSSNFKVFRVYTSNQEFESVRLNETLSSFSDDTKITIRLGRALKKGEYRVKVCQLLVNEQEPCKFLLDAVFAKGMTVRQSKEELIPQLREQCGLDLSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNWEVFLEVLDGVEKMKSMSQLAILSKRWRPSEMKLDPFQELVLESNSVDELREKLSEISGIPLEDIEFAKGRGTFPCDISVLDIHQDLDWNPKVSTLNVWPLYICDDGAVIFYRDRTEEVMELTEEQRNELMKKESSRLQKTGHRVTYSPRKEKALKIYLDGAPNKDVAQD", "length": 1375, "header": "tr|A0A9J7FV92-1|A0A9J7FV92_CRIGR Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 47 OS=Cricetulus griseus OX=10029 GN=Usp47 PE=4 SV=1 CANONICAL=A0A9J7FV92-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FV92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92/entry#A0A9J7FV92-1", "sequence": { "sequence": "MVPGEENQLVPKEIENAAEEPRVLCIIQDTTNSKTVNERITLNLPASTPVRKLFEDVANKVGYVNGTFDLAWGNGVNTADTVPLDHTNDKSLLEANFEPGKKNFLHLTDKDGEQPQMMLDDTSNVDDSMHDRFIGPLPREGSVASTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMSFPEELDMSTFIDIEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSTDDAVDEGICLESSSGTEKISKPGLEKVEMAMTDQRKGSFQVQLGEPNSLMYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPTRNAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIERNTCKIKLFCLHPVKQVMMENKLEVHKDKTLKEAVEMAYKMMDLEEVIPLDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMFDLLLETRKPDQVFQSYKPGEVMVKVHVVDLKAETVAAPITVRAYLNQTVTEFKQLISKATHLPSESMRIVLERCYNDLRLLSVPSKTLKAEGFFRSNKVFVESSETLDHQAAFTDSHLWKLLDRHANTIRLFVLLPEQSPGSYSKRTAYQKAGGDSSNVDDDCERVKGPSGNLKSVDAILEESTEKLKSLSLQQQQDGDNGDSSKSTETSDFENIESPLNERGSSTSVDNRELEQHIQTSDPENFQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADSAQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKADPYAADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFVGVLSSNFKVFRVYTSNQEFESVRLNETLSSFSDDTKITIRLGRALKKGEYRVKVCQLLVNEQEPCKFLLDAVFAKGMTVRQSKEELIPQLREQCGLDLSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNWEVFLEVLDGVEKMKSMSQLAILSKRWRPSEMKLDPFQELVLESNSVDELREKLSEISGIPLEDIEFAKGRGTFPCDISVLDIHQDLDWNPKVSTLNVWPLYICDDGAVIFYRDRTEEVMELTEEQRNELMKKESSRLQKTGHRVTYSPRKEKALKIYLDGAPNKDVAQD", "length": 1375, "header": "tr|A0A9J7FV92-1|A0A9J7FV92_CRIGR Isoform 1 of Ubiquitin carboxyl-terminal hydrolase 47 OS=Cricetulus griseus OX=10029 GN=Usp47 PE=4 SV=1 CANONICAL=A0A9J7FV92-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92/entry#A0A9J7GWA4-1", "sequence": { "sequence": "MKKKFLQIENAAEEPRVLCIIQDTTNSKTVNERITLNLPASTPVRKLFEDVANKVGYVNGTFDLAWGNGVNTADTVPLDHTNDKSLLEANFEPGKKNFLHLTDKDGEQPQMMLDDTSNVDDSMHDRFIGPLPREGSVASTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMSFPEELDMSTFIDIEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSTDDAVDEGICLESSSGTEKISKPGLEKNSLMYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPTRNAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIERNTCKIKLFCLHPVKQVMMENKLEVHKDKTLKEAVEMAYKMMDLEEVIPLDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMFDLLLETRKPDQVFQSYKPGEVMVKVHVVDLKAETVAAPITVRAYLNQTVTEFKQLISKATHLPSESMRIVLERCYNDLRLLSVPSKTLKAEGFFRSNKVFVESSETLDHQAAFTDSHLWKLLDRHANTIRLFVLLPEQSPGSYSKRTAYQKAGGDSSNVDDDCERVKGPSGNLKSVDAILEESTEKLKSLSLQQQQDGDNGDSSKSTETSDFENIESPLNERGSSTSVDNRELEQHIQTSDPENFQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADSAQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKADPYAADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFVGVLSSNFKVFRVYTSNQEFESVRLNETLSSFSDDTKITIRLGRALKKGEYRVKVCQLLVNEQEPCKFLLDAVFAKGMTVRQSKEELIPQLREQCGLDLSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNWEVFLEVLDGVEKMKSMSQLAILSKRWRPSEMKLDPFQELVLESNSVDELREKLSEISGIPLEDIEFAKGRGTFPCDISVLDIHQDLDWNPKVSTLNVWPLYICDDGAVIFYRDRTEEVMELTEEQRNELMKKESSRLQKTGHRVTYSPRKEKALKIYLDGAPNKDVAQD", "length": 1349, "header": "tr|A0A9J7GWA4-1|A0A9J7GWA4_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 47 OS=Cricetulus griseus OX=10029 GN=Usp47 PE=4 SV=1 CANONICAL=A0A9J7FV92-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K6W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92/entry#A0A9J7K6W0-1", "sequence": { "sequence": "MKKKFLQIENAAEEPRVLCIIQDTTNSKTVNERITLNLPASTPVRKLFEDVANKVGYVNGTFDLAWGNGVNTADTVPLDHTNDKSLLEANFEPGKKNFLHLTDKDGEQPQMMLDDTSNVDDSMHDRFIGPLPREGSVASTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMSFPEELDMSTFIDIEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSTDDAVDEGICLESSSGTEKISKPGLEKVEMAMTDQRKGSFQVQLGEPNSLMYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPTRNAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIERNTCKIKLFCLHPVKQVMMENKLEVHKDKTLKEAVEMAYKMMDLEEVIPLDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMFDLLLETRKPDQVFQSYKPGEVMVKVHVVDLKAETVAAPITVRAYLNQTVTEFKQLISKATHLPSESMRIVLERCYNDLRLLSVPSKTLKAEGFFRSNKVFVESSETLDHQAAFTDSHLWKLLDRHANTIRLFVLLPEQSPGSYSKRTAYQKAGGDSSNVDDDCERVKGPSGNLKSVDAILEESTEKLKSLSLQQQQDGDNGDSSKSTETSDFENIESPLNERGSSTSVDNRELEQHIQTSDPENFQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADSAQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKADPYAADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFVGVLSSNFKVFRVYTSNQEFESVRLNETLSSFSDDTKITIRLGRALKKGEYRVKVCQLLVNEQEPCKFLLDAVFAKGMTVRQSKEELIPQLREQCGLDLSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNWEVFLEVLDGVEKMKSMSQLAILSKRWRPSEMKLDPFQELVLESNSVDELREKLSEISGIPLEDIEFAKGRGTFPCDISVLDIHQDLDWNPKVSTLNVWPLYICDDGAVIFYRDRTEEVMELTEEQRNELMKKESSRLQKTGHRVTYSPRKEKALKIYLDGAPNKDVAQD", "length": 1369, "header": "tr|A0A9J7K6W0-1|A0A9J7K6W0_CRIGR Computationally mapped isoform of Ubiquitin carboxyl-terminal hydrolase 47 OS=Cricetulus griseus OX=10029 GN=Usp47 PE=4 SV=1 CANONICAL=A0A9J7FV92-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766617", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766617", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1098, "end_pos": 1100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1201, "end_pos": 1203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FV92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV92" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 168, "end_pos": 564, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1098, "end_pos": 1100 }, { "start_pos": 1201, "end_pos": 1203 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 739, "end_pos": 741 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV99" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769017", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769017", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AQK8-1", "protein_name": "Cytochrome c oxidase assembly protein COX19", "gene_name": "COX19", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSTAMNFGSKSFQPRPPDKGSFPLDHFGECKSFKEKFMKCLRDNNFENALCRNESKEYLECRMERQLMAQEPLEKLGFGDLKDGKSDRD", "length": 89 }, "evidence": [ { "id": "A0A9J7FV99", "url": "https://omabrowser.org/oma/group/A0A9J7FV99/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A8E4L1-1", "protein_name": "Cytochrome c oxidase assembly protein COX19", "gene_name": "COX19", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSTAMNFGSKSFQPRPPDKGSFPLDHFGECKSFKEKFMKCLRDNNFENALCRNESKEYLECRMERQLMAQEPLEKLGFGDLIDGKSDKN", "length": 89 }, "evidence": [ { "id": "A0A9J7FV99", "url": "https://omabrowser.org/oma/group/A0A9J7FV99/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1JGR4-1", "protein_name": "CHCH domain-containing protein", "gene_name": "Dmel\\CG42496", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTSQIYSQKKFVPTPPEKGSFPLDHEGLCKKQFLLYASCLRKNAQDTSQCRQDAQNYLACRMDNNLMEKTEWSKLGFHDQSTKTDQKEPEVQKQ", "length": 94 }, "evidence": [ { "id": "A0A9J7FV99", "url": "https://omabrowser.org/oma/group/A0A9J7FV99/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3E731-1", "protein_name": "Cytochrome c oxidase assembly protein COX19", "gene_name": "COX19", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSGNPGSSLSALRPTPPERGSFPLDHDGECTKYMQEYLKCMQLVQNENAMNCRLLAKDYLRCRMDHQLMDYDEWSHLGLPEDAPGNNGKTIKDATDNK", "length": 98 }, "evidence": [ { "id": "A0A9J7FV99", "url": "https://omabrowser.org/oma/group/A0A9J7FV99/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q49B96-1", "protein_name": "Cytochrome c oxidase assembly protein COX19", "gene_name": "COX19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTAMNFGTKSFQPRPPDKGSFPLDHLGECKSFKEKFMKCLHNNNFENALCRKESKEYLECRMERKLMLQEPLEKLGFGDLTSGKSEAKK", "length": 90 }, "evidence": [ { "id": "A0A9J7FV99", "url": "https://omabrowser.org/oma/group/A0A9J7FV99/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54IA0-1", "protein_name": "Cytochrome c oxidase assembly protein COX19", "gene_name": "cox19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MQFAHNSSIQKPTPPDKGSFPLDHDSECSKPMLAYVNCLSENNGLSRFCMEFSKEYLKCRMDNNLMAKEDMDNFGFEEVKKAKIVPAPHYNPNEPIVAGLSRRKRD", "length": 106 }, "evidence": [ { "id": "A0A9J7FV99", "url": "https://omabrowser.org/oma/group/A0A9J7FV99/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8K0C8-1", "protein_name": "Cytochrome c oxidase assembly protein COX19", "gene_name": "Cox19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTAMNFGTKSFQPRPPDKGSFPLDHFGECKSFKEKFMRCLRDKNYENALCRNESKEYLMCRMQRQLMAPEPLEKLGFRDLMEGKPEAKDEC", "length": 92 }, "evidence": [ { "id": "A0A9J7FV99", "url": "https://omabrowser.org/oma/group/A0A9J7FV99/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C9L6-1", "protein_name": "Cytochrome c oxidase 19-2", "gene_name": "COX19-2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTGGAFGGNRGLRPIPPEKGIFPLDHLHECDAEKKEYLGCLKSSAHKSEQCRHLSKKYLQCRMAKNLMAKQDMAELGFSGVKELDSTEDKNTESIEH", "length": 98 }, "evidence": [ { "id": "A0A9J7FV99", "url": "https://omabrowser.org/oma/group/A0A9J7FV99/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV99", "url": 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVB3-1", "uniprot_ac": "A0A9J7FVB3", "uniprot_id": "A0A9J7FVB3_CRIGR", "mass": { "chemical_mass": 63827.0, "monoisotopic_mass": 63827.0 }, "refseq": { "ac": "XP_027265937", "name": "protein inscuteable homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265937" }, "gene_names": [ { "name": "LOC113830639", "type": "recommended", "evidence": [ { "id": "A0A9J7FVB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVB3" } ] }, { "name": "LOC113830639", "type": "synonym", "evidence": [ { "id": "XP_027265937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265937" } ] } ], "protein_names": [ { "name": "Protein inscuteable homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7FVB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVB3/entry#names_and_taxonomy" } ] }, { "name": "protein inscuteable homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027265937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265937" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265937" } ] }, { "annotation": "May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis. May regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVB3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVB3#function" }, { "database": "UniProtKB", "id": "ARBA00054348", "url": "https://www.uniprot.org/uniprotkb/ARBA00054348#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVB3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVB3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113830639", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVB3", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVB3", "database": 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eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614649.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003509142.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509142", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509142" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVF0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVF0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100761874", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVF0", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVF0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761874", "url": "https://www.ncbi.nlm.nih.gov/gene/100761874", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761874", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761874", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVF0", "url": "https://www.orthodb.org/?gene=A0A9J7FVF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509142", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509142", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FVF0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSISHSNIMKTGNFSESTEFYLLGLSDNQDLQPVLFGVFLSMYLITMTGNLLIILATVYDSNLHTPMYFFISNLSFIDICFTTTTIPQMLVNIKAQVSSISYTGCLTQICFVLTFAGLENGILVMMAYDRFVAICHPLRYTVIMNPKVCGLLVLLSLLISILDALLHTLMALRLSFCTKVEIPHFFCELAHILKLACSNIFINNILVYLVTSLLGVLPLSGIIFSYTRIISSVLKVPSAAGKYKAFSICASHLIVVSLFYGTGFGVYLSSAGSHSSRKSAIASVMYTVVTPMMNPFIYSLRNKDMVGAFKKLFCRITTSL", "length": 321, "header": "tr|A0A9J7FVF0-1|A0A9J7FVF0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100761874 PE=3 SV=1 CANONICAL=A0A9J7FVF0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVF0/entry#A0A9J7FVF0-1", "sequence": { "sequence": "MFSISHSNIMKTGNFSESTEFYLLGLSDNQDLQPVLFGVFLSMYLITMTGNLLIILATVYDSNLHTPMYFFISNLSFIDICFTTTTIPQMLVNIKAQVSSISYTGCLTQICFVLTFAGLENGILVMMAYDRFVAICHPLRYTVIMNPKVCGLLVLLSLLISILDALLHTLMALRLSFCTKVEIPHFFCELAHILKLACSNIFINNILVYLVTSLLGVLPLSGIIFSYTRIISSVLKVPSAAGKYKAFSICASHLIVVSLFYGTGFGVYLSSAGSHSSRKSAIASVMYTVVTPMMNPFIYSLRNKDMVGAFKKLFCRITTSL", "length": 321, "header": "tr|A0A9J7FVF0-1|A0A9J7FVF0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100761874 PE=3 SV=1 CANONICAL=A0A9J7FVF0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 100% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269202" } ] }, { "annotation": "Possible taste receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7#function" }, { "database": "UniProtKB", "id": "ARBA00053672", "url": "https://www.uniprot.org/uniprotkb/ARBA00053672#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100767629", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVG7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVG7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100767629", "url": "https://www.ncbi.nlm.nih.gov/gene/100767629", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767629", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767629", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVG7", "url": "https://www.orthodb.org/?gene=A0A9J7FVG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269202", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FVG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAGFLLPPGGQAVAPSTCAAQMGLFVALGGSECLLLAAMALDRYLAICRPLYYPQLMTTGLCWALLASCCLGGSVLALGLTTAIFQLPFCHGGLVNHVFCDLPAVLILACGNRDLQEHVLLAACMLLLVLPLILILLSYTRVLVVILGVGDGAGRRKAFNTVASHLTVAVLHYGCATAMYARPLSSRSLEEDKLVSLIYINLTPLLYPAIYTLRNRDMQGALQRLRGLTERRFRGTRGALVVLEVVMHYVPWRTSHILRGYHADWPCAITKN", "length": 273, "header": "tr|A0A9J7FVG7-1|A0A9J7FVG7_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100767629 PE=3 SV=1 CANONICAL=A0A9J7FVG7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7/entry#A0A9J7FVG7-1", "sequence": { "sequence": "MLAGFLLPPGGQAVAPSTCAAQMGLFVALGGSECLLLAAMALDRYLAICRPLYYPQLMTTGLCWALLASCCLGGSVLALGLTTAIFQLPFCHGGLVNHVFCDLPAVLILACGNRDLQEHVLLAACMLLLVLPLILILLSYTRVLVVILGVGDGAGRRKAFNTVASHLTVAVLHYGCATAMYARPLSSRSLEEDKLVSLIYINLTPLLYPAIYTLRNRDMQGALQRLRGLTERRFRGTRGALVVLEVVMHYVPWRTSHILRGYHADWPCAITKN", "length": 273, "header": "tr|A0A9J7FVG7-1|A0A9J7FVG7_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100767629 PE=3 SV=1 CANONICAL=A0A9J7FVG7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767629", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767629", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FVG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVG7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 212, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"name": "Sun1", "type": "recommended", "evidence": [ { "id": "A0A9J7FXV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1" } ] }, { "name": "Sun1", "type": "synonym", "evidence": [ { "id": "XP_027269260", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269260" } ] } ], "protein_names": [ { "name": "SUN domain-containing protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027269260", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269260" }, { "id": "A0A9J7FXV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269260" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sun1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1", "locus": {} } ], "crossref": [ { "id": "cd21439", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21439", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769590", "url": "https://www.ncbi.nlm.nih.gov/gene/100769590", "database": "GeneID", "categories": [ "Genome 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"MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLVTTTATYSSGDSQAVDTHISTSRATPSKEKETRTVKQRRSTSKPAFSINHLSGKGVSSSASHDISCSLRSATTLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKTATQGNGELAAEVTASNGYTCRDCRMLSARTDALTAHPATHGTTSRVYSRDRTLKHRGASFYLDRTLWLAKYTSSSFASFLVQLFQVVLMKLSFESETYKLKGYESRAYESQSYETKSHGSEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLETHTVTHSQLLQLHRVAGAMGRLCTYTGDLLVQALHRTRAAGWSVTKAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGLSLWGQSNFLSLLPVLNWTTMQPAQRVDDPEGVHRPGPVPPSPPLKVDYEASQWPRESDVGQKVASLSAQCHNHDERLAELTFLLQKLQMRVDQVDDGREGLSLWVKDVVGQHLQEMGTTEPLSAKTDLMTFHHEHQVRLSNLEDILRKLTEKSEAIQKELEESKLRAGSRAEEQPLLDRVQHLELELNLLKSQLSDWHHLRTSCEQADARIQETVRLMFSEDQHNGSLEWLLQKLSSRFVSKDELQVLLHDLELKVLQNITHHVTVTGQAPTSEAIVSAMSEAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYNQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPAQ", "length": 916, "header": "tr|A0A9J7FXV1-1|A0A9J7FXV1_CRIGR Isoform 1 of SUN domain-containing protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Sun1 PE=4 SV=1 CANONICAL=A0A9J7FXV1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MMR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1/entry#A0A8C2MMR4-1", "sequence": { "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLVTTTATYSSGDSQAVDTHISTSRATPSKEKETRTVKQRRSTSKPAFSINHLSGKGVSSSASHDISCSLRSATTLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKTATQGNGELAAEVTASNGYTCRDCRMLSARTDALTAHPATHGTTSRVYSRDRTLKHPHLGHCGRMTAGELSRVDGESLCDDCKGKKHLETHTVTHSQLLQLHRVAGAMGRLCTYTGDLLVQALHRTRAAGWSVTKAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGLSLWGQSNFLSLLPVLNWTTMQPAQRVDDPEGVHRPGPVPPSPPLKVDYEASQWPRESDVGQKVASLSAQCHNHDERLAELTFLLQKLQMRVDQVDDGREGLSLWVKDVVGQHLQEMGTTEPLSAKTDLMTFHHEHQVRLSNLEDILRKLTEKSEAIQKELEESKLRAGSRAEEQPLLDRVQHLELELNLLKSQLSDWHHLRTSCEQADARIQETVRLMFSEDQHNGSLEWLLQKLSSRFVSKDELQVLLHDLELKVLQNITHHVTVTGQAPTSEAIVSAMSEAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYNQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPAQ", "length": 850, "header": "tr|A0A8C2MMR4-1|A0A8C2MMR4_CRIGR Computationally mapped isoform of SUN domain-containing protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Sun1 PE=4 SV=1 CANONICAL=A0A9J7FXV1-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MN66-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1/entry#A0A8C2MN66-1", "sequence": { "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLVTTTATYSSGDSQAVDTHISTSRATPSKEKETRTVKQRRSTSKPAFSINHLSGKGVSSSASHDISCSLRSATTLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKTATQGNGELAAEVTASNGYTCRDCRMLSARTDALTAHPATHGTTSRVYSRDRTLKHRKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGLSLWGQSNFLSLLPVLNWTTMQPAQRVDDPEGVHRPGPVPPSPPLKVDYEASQWPRESDVGQKVASLSAQCHNHDERLAELTFLLQKLQMRVDQVDDGREGLSLWVKDVVGQHLQEMGTTEPLSAKTDLMTFHHEHQVRLSNLEDILRKLTEKSEAIQKELEESKLRAGSRAEEQPLLDRVQHLELELNLLKSQLSDWHHLRTSCEQADARIQETVRLMFSEDQHNGSLEWLLQKLSSRFVSKDELQVLLHDLELKVLQNITHHVTVTGQAPTSEAIVSAMSEAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYNQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPAQ", "length": 758, "header": "tr|A0A8C2MN66-1|A0A8C2MN66_CRIGR Computationally mapped isoform of SUN domain-containing protein 1 isoform X8 OS=Cricetulus griseus OX=10029 GN=Sun1 PE=4 SV=1 CANONICAL=A0A9J7FXV1-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MPJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1/entry#A0A8C2MPJ5-1", "sequence": { "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLVTTTATYSSGDSQAVDTHISTSRATPSKEKETRTVKQRRSTSKPAFSINHLSGKGVSSSASHDISCSLRSATTLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKTATQGNGELAAEVTASNGYTCRDCRMLSARTDALTAHPATHGTTSRVYSRDRTLKHRDLLVQALHRTRAAGWSVTKAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGLSLWGQSNFLSLLPVLNWTTMQPAQRVDDPEGVHRPGPVPPSPPLKVDYEASQWPRESDVGQKVASLSAQCHNHDERLAELTFLLQKLQMRVDQVDDGREGLSLWVKDVVGQHLQEMGTTEPLSAKTDLMTFHHEHQVRLSNLEDILRKLTEKSEAIQKELEESKLRAGSRAEEQPLLDRVQHLELELNLLKSQLSDWHHLRTSCEQADARIQETVRLMFSEDQHNGSLEWLLQKLSSRFVSKDELQVLLHDLELKVLQNITHHVTVTGQAPTSEAIVSAMSEAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYNQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPAQ", "length": 791, "header": "tr|A0A8C2MPJ5-1|A0A8C2MPJ5_CRIGR Computationally mapped isoform of SUN domain-containing protein 1 isoform X7 OS=Cricetulus griseus OX=10029 GN=Sun1 PE=4 SV=1 CANONICAL=A0A9J7FXV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1/entry#A0A9J7FVJ7-1", "sequence": { "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLVTTTATYSSGDSQAVDTHISTSRATPSKEKETRTVKQRRSTSKPAFSINHLSGKGVSSSASHDISCSLRSATTLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKTATQGNGELAAEVTASNGYTCRDCRMLSARTDALTAHPATHGTTSRVYSRDRTLKHRDDCKGKKHLETHTVTHSQLLQLHRVAGAMGRLCTYTGDLLVQALHRTRAAGWSVTKAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGLSLWGQSNFLSLLPVLNWTTMQPAQRVDDPEGVHRPGPVPPSPPLKVDYEASQWPRESDVGQKVASLSAQCHNHDERLAELTFLLQKLQMRVDQVDDGREGLSLWVKDVVGQHLQEMGTTEPLSAKTDLMTFHHEHQVRLSNLEDILRKLTEKSEAIQKELEESKLRAGSRAEEQPLLDRVQHLELELNLLKSQLSDWHHLRTSCEQADARIQETVRLMFSEDQHNGSLEWLLQKLSSRFVSKDELQVLLHDLELKVLQNITHHVTVTGQAPTSEAIVSAMSEAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYNQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPAQ", "length": 828, "header": "tr|A0A9J7FVJ7-1|A0A9J7FXV1_CRIGR Computationally mapped isoform of SUN domain-containing protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Sun1 PE=4 SV=1 CANONICAL=A0A9J7FXV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1/entry#A0A9J7FXQ3-1", "sequence": { "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLVTTTATYSSGDSQAVDTHISTSRATPSKEKETRTVKQRRSTSKPAFSINHLSGKGVSSSASHDISCSLRSATTLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKTATQGNGELAAEVTASNGYTCRDCRMLSARTDALTAHPATHGTTSRVYSRDRTLKHRGASFYLDRTLWLAKYTSSSFASFLVQLFQVVLMKLSFESETYKLKGYESRAYESQSYETKSHGSEGDDCKGKKHLETHTVTHSQLLQLHRVAGAMGRLCTYTGDLLVQALHRTRAAGWSVTKAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGLSLWGQSNFLSLLPVLNWTTMQPAQRVDDPEGVHRPGPVPPSPPLKVDYEASQWPRESDVGQKVASLSAQCHNHDERLAELTFLLQKLQMRVDQVDDGREGLSLWVKDVVGQHLQEMGTTEPLSAKTDLMTFHHEHQVRLSNLEDILRKLTEKSEAIQKELEESKLRAGSRAEEQPLLDRVQHLELELNLLKSQLSDWHHLRTSCEQADARIQETVRLMFSEDQHNGSLEWLLQKLSSRFVSKDELQVLLHDLELKVLQNITHHVTVTGQAPTSEAIVSAMSEAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYNQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPAQ", "length": 894, "header": "tr|A0A9J7FXQ3-1|A0A9J7FXQ3_CRIGR Computationally mapped isoform of SUN domain-containing protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Sun1 PE=4 SV=1 CANONICAL=A0A9J7FXV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1/entry#A0A9J7FXV1-1", "sequence": { "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLVTTTATYSSGDSQAVDTHISTSRATPSKEKETRTVKQRRSTSKPAFSINHLSGKGVSSSASHDISCSLRSATTLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKTATQGNGELAAEVTASNGYTCRDCRMLSARTDALTAHPATHGTTSRVYSRDRTLKHRGASFYLDRTLWLAKYTSSSFASFLVQLFQVVLMKLSFESETYKLKGYESRAYESQSYETKSHGSEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLETHTVTHSQLLQLHRVAGAMGRLCTYTGDLLVQALHRTRAAGWSVTKAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGLSLWGQSNFLSLLPVLNWTTMQPAQRVDDPEGVHRPGPVPPSPPLKVDYEASQWPRESDVGQKVASLSAQCHNHDERLAELTFLLQKLQMRVDQVDDGREGLSLWVKDVVGQHLQEMGTTEPLSAKTDLMTFHHEHQVRLSNLEDILRKLTEKSEAIQKELEESKLRAGSRAEEQPLLDRVQHLELELNLLKSQLSDWHHLRTSCEQADARIQETVRLMFSEDQHNGSLEWLLQKLSSRFVSKDELQVLLHDLELKVLQNITHHVTVTGQAPTSEAIVSAMSEAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYNQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPAQ", "length": 916, "header": "tr|A0A9J7FXV1-1|A0A9J7FXV1_CRIGR Isoform 1 of SUN domain-containing protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Sun1 PE=4 SV=1 CANONICAL=A0A9J7FXV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G008-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1/entry#A0A9J7G008-1", "sequence": { "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLVTTTATYSSGDSQAVDTHISTSRATPSKEKETRTVKQRRSTSKPAFSINHLSGKGVSSSASHDISCSLRSATTLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKTATQGNGELAAEVTASNGYTCRDCRMLSARTDALTAHPATHGTTSRVYSRDRTLKHPHLGHCGRMTAGELSRVDGESLCDDCKGKKHLETHTVTHSQLLQLHRVAGAMGRLCTYTGDLLVQALHRTRAAGWSVTKAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGLSLWGQSNFLSLLPVLNWTTMQPAQRVDDPEGVHRPGPVPPSPPLKVDYEASQWPRESDVGQKVASLSAQCHNHDERLAELTFLLQKLQMRVDQVDDGREGLSLWVKDVVGQHLQEMGTTEPLSAKTDLMTFHHEHQVRLSNLEDILRKLTEKSEAIQKELEESKLRAGRAEEQPLLDRVQHLELELNLLKSQLSDWHHLRTSCEQADARIQETVRLMFSEDQHNGSLEWLLQKLSSRFVSKDELQVLLHDLELKVLQNITHHVTVTGQAPTSEAIVSAMSEAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYNQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPAQ", "length": 849, "header": "tr|A0A9J7G008-1|A0A9J7G008_CRIGR Computationally mapped isoform of SUN domain-containing protein 1 isoform X5 OS=Cricetulus griseus OX=10029 GN=Sun1 PE=4 SV=1 CANONICAL=A0A9J7FXV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1/entry#A0A9J7JPY3-1", "sequence": { "sequence": "MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHRLEPVFDSPRMSRRSLRLVTTTATYSSGDSQAVDTHISTSRATPSKEKETRTVKQRRSTSKPAFSINHLSGKGVSSSASHDISCSLRSATTLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKTATQGNGELAAEVTASNGYTCRDCRMLSARTDALTAHPATHGTTSRVYSRDRTLKHRGASFYLDRTLWLAKYTSSSFASFLVQLFQVVLMKLSFESETYKLKGYESRAYESQSYETKSHGSEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLETHTVTHSQLLQLHRVAGAMGRLCTYTGDLLVQALHRTRAAGWSVTKAMWSVLWLAVTAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGLSLWGQSNFLSLLPVLNWTTMQPAQRVDDPEGVHRPGPVPPSPPLKVDYEASQWPRESDVGQKVASLSAQCHNHDERLAELTFLLQKLQMRVDQVDDGREGLSLWVKDVVGQHLQEMGTTEPLSAKTDLMTFHHEHQVRLSNLEDILRKLTEKSEAIQKELEESKLRAGRAEEQPLLDRVQHLELELNLLKSQLSDWHHLRTSCEQADARIQETVRLMFSEDQHNGSLEWLLQKLSSRFVSKDELQVLLHDLELKVLQNITHHVTVTGQAPTSEAIVSAMSEAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPRDFAVYGLETEYQEEGQPLGRFTYNQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPAQ", "length": 915, "header": "tr|A0A9J7JPY3-1|A0A9J7JPY3_CRIGR Computationally mapped isoform of SUN domain-containing protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sun1 PE=4 SV=1 CANONICAL=A0A9J7FXV1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 83, "start_aa": "Thr", "end_pos": 83, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr83", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVJ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVJ7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVJ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVJ7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769590", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769590", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration", "id": "GO:0021817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021817", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1" } ], "pmid": "" }, { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-membrane adaptor activity", "id": "GO:0043495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043495", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1" } ], "pmid": "" }, { "name": "meiotic nuclear membrane microtubule tethering complex", "id": "GO:0034993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034993", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 837, "end_pos": 839, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FXV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXV1" }, { "id": "PS51469", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51469" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUN", "eco_id": "ECO_0000259", "start_pos": 754, "end_pos": 915, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 83 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { 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Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269180" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100759650", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK1", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVK1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVK1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759650", "url": "https://www.ncbi.nlm.nih.gov/gene/100759650", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759650", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759650", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVK1", "url": "https://www.orthodb.org/?gene=A0A9J7FVK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269180", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FVK1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMHWNNWTLNYDFILLGIFDHSPLHTFFFSLTLGIFFMALMGNSTMVLLIYLDAQLHTPMYILLSQLSLMDLMLICTTVPQMAFNFLSGNKSISMAGCGSQIFFYVSLLGSECFLLASMAYDRYVAICHPLRYPILMSHKICGLIAASSWILGSLDGIIEVAVAMSFSYCGAREIPHFFCEVPALLTLSCSDTLIYEKMIFFCCVIMLIFPVAIIIASYTRVILAVIRMASAESRHKAFATCSSHLVVVGMYYGAAMFIYMRPSSGRSPNQDKMVSAFYTILTPMLNPLIYSLRNREVARAFVKVLGMDKAAA", "length": 313, "header": "tr|A0A9J7FVK1-1|A0A9J7FVK1_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100759650 PE=3 SV=1 CANONICAL=A0A9J7FVK1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK1/entry#A0A9J7FVK1-1", "sequence": { "sequence": "MMHWNNWTLNYDFILLGIFDHSPLHTFFFSLTLGIFFMALMGNSTMVLLIYLDAQLHTPMYILLSQLSLMDLMLICTTVPQMAFNFLSGNKSISMAGCGSQIFFYVSLLGSECFLLASMAYDRYVAICHPLRYPILMSHKICGLIAASSWILGSLDGIIEVAVAMSFSYCGAREIPHFFCEVPALLTLSCSDTLIYEKMIFFCCVIMLIFPVAIIIASYTRVILAVIRMASAESRHKAFATCSSHLVVVGMYYGAAMFIYMRPSSGRSPNQDKMVSAFYTILTPMLNPLIYSLRNREVARAFVKVLGMDKAAA", "length": 313, "header": "tr|A0A9J7FVK1-1|A0A9J7FVK1_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100759650 PE=3 SV=1 CANONICAL=A0A9J7FVK1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"name": "F-box/SPRY domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027269068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269068" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269068" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fbxo45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK9", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12907", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12907", "database": "CDD", "categories": [ "Protein Classification" ] 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"MADPGVRRGEAGRGDGGAGPGAGAASGGAGCGGASAGSGSSGAGGRLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKVRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKACLYPAVSAVYGNTEVTLVYLGKPLDG", "length": 294, "header": "tr|A0A9J7FVK9-1|A0A9J7FVK9_CRIGR Isoform 1 of F-box/SPRY domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Fbxo45 PE=3 SV=1 CANONICAL=A0A9J7FVK9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVK9/entry#A0A9J7FVK9-1", "sequence": { "sequence": "MADPGVRRGEAGRGDGGAGPGAGAASGGAGCGGASAGSGSSGAGGRLPSRVLELVFSYLELSELRSCALVCKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKVRAFQHAFSTNDCSRNVYIKKNGFTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPLGTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKACLYPAVSAVYGNTEVTLVYLGKPLDG", "length": 294, "header": "tr|A0A9J7FVK9-1|A0A9J7FVK9_CRIGR Isoform 1 of F-box/SPRY domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Fbxo45 PE=3 SV=1 CANONICAL=A0A9J7FVK9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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[ "Protein" ] }, { "id": "A0A9J7FVN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGGRRRPREAGLGLVSFEDIAVEFTWQEWQDLNEGQRTLYRDVMLENYSNLLFLGHCKTKPELIFNLEQRLGSWIVGEASDQSIPEFQGMNTLSKICPETKARHVWQVALDSDTSKKLTGVGKAFNVSANHVSNQNIKNENPLGICPRKLFLWKNVCFHSDADELEVEPDDLNETIKSIRHPEHVSLYKSQSSQSYFQSLIPGSTFNTKEVLLTHKFSEYAKSLGDTAFIGKEMAQIRGKSFECNISQIKCNKSDLDENEQIHSRQKHYKCNDFENPFITESYLPKHKGQHAEEKLFAQEEYEFSQQSEVSLHQKIHRGKKSYQCKICGKCFHWKTSFNRHHSTHTGEKPYECTECRKAFCQKSHLTQHQRVHTGERPYICLECRKAFYRKSELTDHQRIHTGEKPYECKECGKAFCQKPQLTLHQRIHTGEKPYECTECGKAFSTKSYLTVHQRTHTGEKPYECTVCRKSFICKSSFSHHWRTHTGEKPYECKQCMKTFYRKSGLTRHQRTHTGDKPYECQLCEKAFYCTSHLTVHQRTHTGEKPYECKECRKSFYDKSNLRRHQKIHTMEKACECKQCNKSLLSNTSQHQTMYSEYEECKKALHHKTNFT", "length": 613, "header": "tr|A0A9J7FVN1-1|A0A9J7FVN1_CRIGR Isoform 1 of Zinc finger protein 39 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100768835 PE=3 SV=1 CANONICAL=A0A9J7FVN1-1" }, "isoforms": [ { "isoform_ac": "A0A061I9W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1/entry#A0A061I9W2-1", "sequence": { "sequence": "MPWKPEMGLVSFEDIAVEFTWQEWQDLNEGQRTLYRDVMLENYSNLLFLGHCKTKPELIFNLEQRLGSWIVGEASDQSIPEFQGMNTLSKICPETKARHVWQVALDSDTSKKLTGVGKAFNVSANHVSNQNIKNENPLGICPRKLFLWKNVCFHSDADELEVEPDDLNETIKSIRHPEHVSLYKSQSSQSYFQSLIPGSTFNTKEVLLTHKFSEYAKSLGDTAFIGKEMAQIRGKSFECNISQIKCNKSDLDENEQIHSRQKHYKCNDFENPFITESYLPKHKGQHAEEKLFAQEEYEFSQQSEVSLHQKIHRGKKSYQCKICGKCFHWKTSFNRHHSTHTGEKPYECTECRKAFCQKSHLTQHQRVHTGERPYICLECRKAFYRKSELTDHQRIHTGEKPYECKECGKAFCQKPQLTLHQRIHTGEKPYECTECGKAFSTKSYLTVHQRTHTGEKPYECTVCRKSFICKSSFSHHWRTHTGEKPYECKQCMKTFYRKSGLTRHQRTHTGDKPYECQLCEKAFYCTSHLTVHQRTHTGEKPYECKECRKSFYDKSNLRRHQKIHTMEKACECKQCNKSLLSNTSQHQTMYSEYEECKKALHHKTNFT", "length": 607, "header": "tr|A0A061I9W2-1|A0A061I9W2_CRIGR Computationally mapped isoform of Zinc finger protein 39 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100768835 PE=3 SV=1 CANONICAL=A0A9J7FVN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1/entry#A0A9J7FVN1-1", "sequence": { "sequence": "MVGGRRRPREAGLGLVSFEDIAVEFTWQEWQDLNEGQRTLYRDVMLENYSNLLFLGHCKTKPELIFNLEQRLGSWIVGEASDQSIPEFQGMNTLSKICPETKARHVWQVALDSDTSKKLTGVGKAFNVSANHVSNQNIKNENPLGICPRKLFLWKNVCFHSDADELEVEPDDLNETIKSIRHPEHVSLYKSQSSQSYFQSLIPGSTFNTKEVLLTHKFSEYAKSLGDTAFIGKEMAQIRGKSFECNISQIKCNKSDLDENEQIHSRQKHYKCNDFENPFITESYLPKHKGQHAEEKLFAQEEYEFSQQSEVSLHQKIHRGKKSYQCKICGKCFHWKTSFNRHHSTHTGEKPYECTECRKAFCQKSHLTQHQRVHTGERPYICLECRKAFYRKSELTDHQRIHTGEKPYECKECGKAFCQKPQLTLHQRIHTGEKPYECTECGKAFSTKSYLTVHQRTHTGEKPYECTVCRKSFICKSSFSHHWRTHTGEKPYECKQCMKTFYRKSGLTRHQRTHTGDKPYECQLCEKAFYCTSHLTVHQRTHTGEKPYECKECRKSFYDKSNLRRHQKIHTMEKACECKQCNKSLLSNTSQHQTMYSEYEECKKALHHKTNFT", "length": 613, "header": "tr|A0A9J7FVN1-1|A0A9J7FVN1_CRIGR Isoform 1 of Zinc finger protein 39 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100768835 PE=3 SV=1 CANONICAL=A0A9J7FVN1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768835", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768835", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN1", "url": 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[], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 246, "end_pos": 248 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 588, "end_pos": 590 }, { "start_pos": 611, "end_pos": 613 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVN6-1", "uniprot_ac": "A0A9J7FVN6", "uniprot_id": "A0A9J7FVN6_CRIGR", "mass": { "chemical_mass": 55209.0, "monoisotopic_mass": 55209.0 }, "refseq": { "ac": "XP_027269537", "name": "beta-1,3-glucosyltransferase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269537" }, "gene_names": [ { "name": "B3glct", "type": "recommended", "evidence": [ { "id": "A0A9J7FVN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6" } ] }, { "name": "B3glct", "type": "synonym", "evidence": [ { "id": "XP_027269537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269537" } ] } ], "protein_names": [ { "name": "Beta-1,3-glucosyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7FVN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6/entry#names_and_taxonomy" } ] }, { "name": "Beta 3-glucosyltransferase", "type": "synonym", "evidence": [ { "id": "A0A9J7FVN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6/entry#names_and_taxonomy" } ] }, { "name": "Beta-3-glycosyltransferase-like", "type": "synonym", "evidence": [ { "id": "A0A9J7FVN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6/entry#names_and_taxonomy" } ] }, { "name": "beta-1,3-glucosyltransferase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027269537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269537" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269537" } ] }, { "annotation": "Beta-1,3-glucosyltransferase involved in one of the two pathways responsible for protein O-linked fucosylation, a unique post-translational modification of cysteine-knotted proteins that regulates various biological processes. This pathway targets proteins with Thrombospondin type-1 (TSP1) repeats (TSR) in the endoplasmic reticulum. It starts with POFUT2, which attaches fucose via an O-glycosidic bond to a conserved serine or threonine residue. B3GLCT extends this modification by transferring a glucose molecule from UDP-glucose to the fucose.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6#function" }, { "database": "UniProtKB", "id": "ARBA00094328", "url": "https://www.uniprot.org/uniprotkb/ARBA00094328#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "B3glct", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVN6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVN6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100759864", "url": "https://www.ncbi.nlm.nih.gov/gene/100759864", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759864", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759864", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVN6", "url": "https://www.orthodb.org/?gene=A0A9J7FVN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10811", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10811", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "70543", "url": "https://www.rhea-db.org/rhea/70543", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "70547", "url": "https://www.rhea-db.org/rhea/70547", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPPALLALLSCSVAFALVSEEIKEKVKHSQDLDQSSQSRKHDIDLKEIVFVIQSQSNPFHAKRAEQLRRSILQQASNLTQDLPRVLLLHQLAKQEGAWTILPLLPHFSVTYSKNSAWIFFSEEETRIQIRRLLETLRRFDPSKEWFLGKALHDEESTIIHHYAFSENPTAFKYPDFAAGWALSVPLVNKLAKRLKSEPLKSDFTIDLKHEIALYIWDKGGGPPLTPVPEFCTDDAGSHCATTFHSFLPLCGTPVNKEEIFVAVKTCKKFHGDRIPIVKKTWAAQASLIEYYSDYAESPIPTVDLGIPNTDRGHCGKTFAILERFLNRSHDKVAWLVIVDDDTLISISRLRHLLSCYDSSDAVFLGERYGYGLGTGGYSYVTGGGGMVFSREAIQRLLASNCRCYSNDAPDDMVLGMCFSGLGIPVTHSPLFHQARPVDYPKDYLSHQIPISFHKHWHIDPVKVYLTWLAPSEEGSATQKTQKDPREEL", "length": 489, "header": "tr|A0A9J7FVN6-1|A0A9J7FVN6_CRIGR Isoform 1 of Beta-1,3-glucosyltransferase OS=Cricetulus griseus OX=10029 GN=B3glct PE=3 SV=1 CANONICAL=A0A9J7FVN6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6/entry#A0A9J7FVN6-1", "sequence": { "sequence": "MQPPALLALLSCSVAFALVSEEIKEKVKHSQDLDQSSQSRKHDIDLKEIVFVIQSQSNPFHAKRAEQLRRSILQQASNLTQDLPRVLLLHQLAKQEGAWTILPLLPHFSVTYSKNSAWIFFSEEETRIQIRRLLETLRRFDPSKEWFLGKALHDEESTIIHHYAFSENPTAFKYPDFAAGWALSVPLVNKLAKRLKSEPLKSDFTIDLKHEIALYIWDKGGGPPLTPVPEFCTDDAGSHCATTFHSFLPLCGTPVNKEEIFVAVKTCKKFHGDRIPIVKKTWAAQASLIEYYSDYAESPIPTVDLGIPNTDRGHCGKTFAILERFLNRSHDKVAWLVIVDDDTLISISRLRHLLSCYDSSDAVFLGERYGYGLGTGGYSYVTGGGGMVFSREAIQRLLASNCRCYSNDAPDDMVLGMCFSGLGIPVTHSPLFHQARPVDYPKDYLSHQIPISFHKHWHIDPVKVYLTWLAPSEEGSATQKTQKDPREEL", "length": 489, "header": "tr|A0A9J7FVN6-1|A0A9J7FVN6_CRIGR Isoform 1 of Beta-1,3-glucosyltransferase OS=Cricetulus griseus OX=10029 GN=B3glct PE=3 SV=1 CANONICAL=A0A9J7FVN6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759864", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759864", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein O-linked glycosylation via fucose", "id": "GO:0036066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036066", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6" } ], "pmid": "" }, { "name": "fucose metabolic process", "id": "GO:0006004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006004", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70543", "name": "", "equation": "3-O-(alpha-L-fucosyl)-L-seryl-[protein] + UDP-alpha-D-glucose = 3-O-(beta-D-glucosyl-(1->3)-alpha-L-fucosyl)-L-seryl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70543", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70543" } ] }, { "id": "70547", "name": "", "equation": "3-O-(alpha-L-fucosyl)-L-threonyl-[protein] + UDP-alpha-D-glucose = 3-O-(beta-D-glucosyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70547", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70547" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FVN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVN6" }, { "id": "PF02434", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02434" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fringe-like glycosyltransferase", "eco_id": "ECO_0000259", "start_pos": 111, "end_pos": 196, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 327, "end_pos": 329 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. 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"categories": [ "Protein" ] }, { "id": "A0A9J7GWW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GX60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GX60-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4M6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4M6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTLNRNQLGPACKTQAVVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITVLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNPCTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPSYNPGSAESESLVNGNHTAQPATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPVVTRSSESPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRTTESPRLGGQLPVVAISLSEYPPSGARSQPTSIPGSPKFQSPVPAPRNKIGTLQDRPPSPFRESPGSERVLTTSPSRQLVGRTFSDGSATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPARTTPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPTLGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSGDLRVPLPRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLTGATVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQAEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAVDQLQEKLVALETGIQKERDKERAELAAGRRHLEARQALYAELQTQLDNCPESVREQLQEQLRREADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVTKRKERLAVLDSQAGQIRAQAVQESERLARDKNAALQLLQKEKERLTVLERRYHSLTGGRPFPKATSTLKEVYRSKMDGEATSPLPRARSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQKVELLPAEPLPPDDPAGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFAAGPSGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKLLKEAHAEKSRLMESRVRLTGARRQQVEREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "length": 1392, "header": "tr|A0A9J7FVP4-1|A0A9J7FVP4_CRIGR Isoform 1 of Pleckstrin homology-like domain family B member 1 OS=Cricetulus griseus OX=10029 GN=Phldb1 PE=4 SV=1 CANONICAL=A0A9J7FVP4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP4/entry#A0A9J7FVP4-1", "sequence": { "sequence": "MDTLNRNQLGPACKTQAVVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITVLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNPCTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPSYNPGSAESESLVNGNHTAQPATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPVVTRSSESPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRTTESPRLGGQLPVVAISLSEYPPSGARSQPTSIPGSPKFQSPVPAPRNKIGTLQDRPPSPFRESPGSERVLTTSPSRQLVGRTFSDGSATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPARTTPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPTLGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSGDLRVPLPRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLTGATVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQAEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAVDQLQEKLVALETGIQKERDKERAELAAGRRHLEARQALYAELQTQLDNCPESVREQLQEQLRREADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVTKRKERLAVLDSQAGQIRAQAVQESERLARDKNAALQLLQKEKERLTVLERRYHSLTGGRPFPKATSTLKEVYRSKMDGEATSPLPRARSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQKVELLPAEPLPPDDPAGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFAAGPSGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKLLKEAHAEKSRLMESRVRLTGARRQQVEREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "length": 1392, "header": "tr|A0A9J7FVP4-1|A0A9J7FVP4_CRIGR Isoform 1 of Pleckstrin homology-like domain family B member 1 OS=Cricetulus griseus OX=10029 GN=Phldb1 PE=4 SV=1 CANONICAL=A0A9J7FVP4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FVW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP4/entry#A0A9J7FVW5-1", "sequence": { "sequence": "MDTLNRNQLGPACKTQAVVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITVLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNPCTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPSYNPGSAESESLVNGNHTAQPATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPVVTRSSESPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRTTESPRLGGQLPVVAISLSEYPPSGARSQPTSIPGSPKFQSPVPAPRNKIGTLQDRPPSPFRESPGSERVLTTSPSRQLVGRTFSDGSATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPARTTPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPTLGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSGDLRVPLPRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLTGATVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQAEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAVDQLQEKLVALETGIQKERDKEADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVTKRKERLAVLDSQAGQIRAQAVQESERLARDKNAALQLLQKEKERLTVLERRYHSLTGGRPFPKATSTLKEVYRSKMDGEATSPLPRARSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQKGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFAAGPSGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKLLKEAHAEKSRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "length": 1323, "header": "tr|A0A9J7FVW5-1|A0A9J7FVW5_CRIGR Computationally mapped isoform of Pleckstrin homology-like domain family B member 1 OS=Cricetulus griseus OX=10029 GN=Phldb1 PE=4 SV=1 CANONICAL=A0A9J7FVP4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP4/entry#A0A9J7GVU0-1", "sequence": { "sequence": "MDTLNRNQLGPACKTQAVVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITVLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNPCTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPSYNPGSAESESLVNGNHTAQPATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPVVTRSSESPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRTTESPRLGGQLPVVAISLSEYPPSGARSQPTSIPGSPKFQSPVPAPRNKIGTLQDRPPSPFRESPGSERVLTTSPSRQLVGRTFSDGSATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPARTTPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPTLGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSGDLRVPLPRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLTGATVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQAEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAVDQLQEKLVALETGIQKERDKERAELAAGRRHLEARQALYAELQTQLDNCPESVREQLQEQLRREADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVTKRKERLAVLDSQAGQIRAQAVQESERLARDKNAALQLLQKEKERLTVLERRYHSLTGGRPFPKATSTLKEVYRSKMDGEATSPLPRARSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQKGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFAAGPSGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKLLKEAHAEKSRLMESRVRLTGARRQQVEREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "length": 1377, "header": "tr|A0A9J7GVU0-1|A0A9J7GVU0_CRIGR Computationally mapped isoform of Pleckstrin homology-like domain family B member 1 OS=Cricetulus griseus OX=10029 GN=Phldb1 PE=4 SV=1 CANONICAL=A0A9J7FVP4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP4/entry#A0A9J7GWW4-1", "sequence": { "sequence": "MDTLNRNQLGPACKTQAVVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITVLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNPCTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPSYNPGSAESESLVNGNHTAQPATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPVVTRSSESPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRTTESPRLGGQLPVVAISLSEYPPSGARSQPTSIPGSPKFQSPVPAPRNKIGTLQDRPPSPFRESPGSERVLTTSPSRQLVGRTFSDGSATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPARTTPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPTLGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSGDLRVPLPRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLTGATVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQAEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAVDQLQEKLVALETGIQKERDKEADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVTKRKERLAVLDSQAGQIRAQAVQESERLARDKNAALQLLQKEKERLTVLERRYHSLTGGRPFPKATSTLKEVYRSKMDGEATSPLPRARSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQKVELLPAEPLPPDDPAGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFAAGPSGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKLLKEAHAEKSRLMESRVRLTGARRQQVEREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "length": 1349, "header": "tr|A0A9J7GWW4-1|A0A9J7GWW4_CRIGR Computationally mapped isoform of Pleckstrin homology-like domain family B member 1 OS=Cricetulus griseus OX=10029 GN=Phldb1 PE=4 SV=1 CANONICAL=A0A9J7FVP4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GX60-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP4/entry#A0A9J7GX60-1", "sequence": { "sequence": "MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPSYNPGSAESESLVNGNHTAQPATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPVVTRSSESPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRTTESPRLGGQLPVVAISLSEYPPSGARSQPTSIPGSPKFQSPVPAPRNKIGTLQDRPPSPFRESPGSERVLTTSPSRQLVGRTFSDGSATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPARTTPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPTLGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSGDLRVPLPRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLTGATVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQAEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAVDQLQEKLVALETGIQKERDKERAELAAGRRHLEARQALYAELQTQLDNCPESVREQLQEQLRREADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVTKRKERLAVLDSQAGQIRAQAVQESERLARDKNAALQLLQKEKERLTVLERRYHSLTGGRPFPKATSTLKEVYRSKMDGEATSPLPRARSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQKVELLPAEPLPPDDPAGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFAAGPSGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKLLKEAHAEKSRLMESRVRLTGARRQQVEREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "length": 1272, "header": "tr|A0A9J7GX60-1|A0A9J7GX60_CRIGR Computationally mapped isoform of Pleckstrin homology-like domain family B member 1 isoform X8 OS=Cricetulus griseus OX=10029 GN=Phldb1 PE=4 SV=1 CANONICAL=A0A9J7FVP4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GY47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP4/entry#A0A9J7GY47-1", "sequence": { "sequence": "MDTLNRNQLGPACKTQAVVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITVLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNPCTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPSYNPGSAESESLVNGNHTAQPATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPVVTRSSESPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRTTESPRLGGQLPVVAISLSEYPPSGARSQPTSIPGSPKFQSPVPAPRNKIGTLQDRPPSPFRESPGSERVLTTSPSRQLVGRTFSDGSATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPARTTPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPTLGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSGDLRVPLPRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLTGATVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQAEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAVDQLQEKLVALETGIQKERDKERAELAAGRRHLEARQALYAELQTQLDNCPESVREQLQEQLRREADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVTKRKERLAVLDSQAGQIRAQAVQESERLARDKNAALQLLQKEKERLTVLERRYHSLTGGRPFPKATSTLKEVYRSKMDGEATSPLPRARSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQKVELLPAEPLPPDDPAGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFAAGPSGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKLLKEAHAEKSRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "length": 1381, "header": "tr|A0A9J7GY47-1|A0A9J7GY47_CRIGR Computationally mapped isoform of Pleckstrin homology-like domain family B member 1 OS=Cricetulus griseus OX=10029 GN=Phldb1 PE=4 SV=1 CANONICAL=A0A9J7FVP4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP4/entry#A0A9J7GZT3-1", "sequence": { "sequence": "MDTLNRNQLGPACKTQAVVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITVLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNPCTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPSYNPGSAESESLVNGNHTAQPATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPVVTRSSESPRLGRKGGHERPPSPGLRGLLTDSPAATVLAEARRTTESPRLGGQLPVVAISLSEYPPSGARSQPTSIPGSPKFQSPVPAPRNKIGTLQDRPPSPFRESPGSERVLTTSPSRQLVGRTFSDGSATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPARTTPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPTLGESLAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSGDLRVPLPRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLTGATVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQAEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAVDQLQEKLVALETGIQKERDKERAELAAGRRHLEARQALYAELQTQLDNCPESVREQLQEQLRREADALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSVTKRKERLAVLDSQAGQIRAQAVQESERLARDKNAALQLLQKEKERLTVLERRYHSLTGGRPFPKATSTLKEVYRSKMDGEATSPLPRARSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQKGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFAAGPSGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKLLKEAHAEKSRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKSPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "length": 1366, "header": "tr|A0A9J7GZT3-1|A0A9J7GZT3_CRIGR Computationally mapped isoform of Pleckstrin homology-like domain family B member 1 OS=Cricetulus griseus OX=10029 GN=Phldb1 PE=4 SV=1 CANONICAL=A0A9J7FVP4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K4M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP4/entry#A0A9J7K4M6-1", "sequence": { "sequence": 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NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the carboxy end.", "evidence": [ { "database": "RefSeq", "id": "XP_027269565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269565" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100762779", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP6", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVP6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVP6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762779", "url": "https://www.ncbi.nlm.nih.gov/gene/100762779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762779", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762779", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVP6", "url": "https://www.orthodb.org/?gene=A0A9J7FVP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FVP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEFKNDTQISKFILLGISEDPLWQPFLFGLFLFMYLVTLLGNLLIIIATVTDSHLHTPMYFFLSNLSFADICFTSASIPKMLVNIQTQNMAITYEGCITQVYFFILFGVLDNFLLAVMAYDRYVAICHPLHYTVIMNSHLCGLLVLGSWVTTALNSLLQSSMALRLSFCTDLKIPHFVCELNQLVLLACNDTFPNDMVMYFAAVLLGGGPLAGILYSYSKIVSSIRAISSSQGKYKAFSTCASHLSVVSLFYSTLLGVYLSSSVTQNSHSTARASVMYSVVTPMLNPFIYSLRNNELMGALRRLFRRNLILGEGLLG", "length": 317, "header": "tr|A0A9J7FVP6-1|A0A9J7FVP6_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100762779 PE=3 SV=1 CANONICAL=A0A9J7FVP6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVP6/entry#A0A9J7FVP6-1", "sequence": { "sequence": "MEFKNDTQISKFILLGISEDPLWQPFLFGLFLFMYLVTLLGNLLIIIATVTDSHLHTPMYFFLSNLSFADICFTSASIPKMLVNIQTQNMAITYEGCITQVYFFILFGVLDNFLLAVMAYDRYVAICHPLHYTVIMNSHLCGLLVLGSWVTTALNSLLQSSMALRLSFCTDLKIPHFVCELNQLVLLACNDTFPNDMVMYFAAVLLGGGPLAGILYSYSKIVSSIRAISSSQGKYKAFSTCASHLSVVSLFYSTLLGVYLSSSVTQNSHSTARASVMYSVVTPMLNPFIYSLRNNELMGALRRLFRRNLILGEGLLG", "length": 317, "header": "tr|A0A9J7FVP6-1|A0A9J7FVP6_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100762779 PE=3 SV=1 CANONICAL=A0A9J7FVP6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266264" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266264", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266264" } ] }, { "annotation": "Major acute phase reactant. Apolipoprotein of the HDL complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS7#function" }, { "database": "UniProtKB", "id": "RU000539", "url": "https://www.uniprot.org/uniprotkb/RU000539#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100750598", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS7", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100750598", "url": "https://www.ncbi.nlm.nih.gov/gene/100750598", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750598", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750598", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVS7", "url": "https://www.orthodb.org/?gene=A0A9J7FVS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23424:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23424:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266264", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266264", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FVS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLLTGLIFCSLVLGVSSWLSFIDEAYLGAGDMWRAYSDMKEANWKNSDKYFHARGNYDAAQRGPGGVWAAEILSDARENIQMFLGRGHEDSLADQEANRWGRSGNDPNHYRPKGLPDKY", "length": 120, "header": "tr|A0A9J7FVS7-1|A0A9J7FVS7_CRIGR Isoform 1 of Serum amyloid A protein OS=Cricetulus griseus OX=10029 GN=LOC100750598 PE=3 SV=1 CANONICAL=A0A9J7FVS7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS7/entry#A0A9J7FVS7-1", "sequence": { "sequence": "MKLLTGLIFCSLVLGVSSWLSFIDEAYLGAGDMWRAYSDMKEANWKNSDKYFHARGNYDAAQRGPGGVWAAEILSDARENIQMFLGRGHEDSLADQEANRWGRSGNDPNHYRPKGLPDKY", "length": 120, "header": "tr|A0A9J7FVS7-1|A0A9J7FVS7_CRIGR Isoform 1 of Serum amyloid A protein OS=Cricetulus griseus OX=10029 GN=LOC100750598 PE=3 SV=1 CANONICAL=A0A9J7FVS7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0006953", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVV9-1", "uniprot_ac": "A0A9J7FVV9", "uniprot_id": "A0A9J7FVV9_CRIGR", "mass": { "chemical_mass": 87224.0, "monoisotopic_mass": 87224.0 }, "refseq": { "ac": "XP_007640760", "name": "centrosomal protein of 63 kDa isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640760" }, "gene_names": [ { "name": "Cep63", "type": "recommended", "evidence": [ { "id": "A0A9J7FVV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" } ] }, { "name": "Cep63", "type": "synonym", "evidence": [ { "id": "XP_007640760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640760" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 63 kDa", "type": "recommended", "evidence": [ { "id": "A0A9J7FVV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 63 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007640760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640760" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 232 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613866.1) and transcript sequence (IACG01022274.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007640760.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640760" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cep63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100771874", "url": "https://www.ncbi.nlm.nih.gov/gene/100771874", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031470", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031470", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771874", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771874", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVV9", "url": "https://www.orthodb.org/?gene=A0A9J7FVV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18875:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18875:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17045", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17045", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640760", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FVV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYX8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G007", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G007", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G007-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G007-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWF7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQI2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQI2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPDPLLFACGCPGTAPVGLSDYSMCSSVPASQTTAMTWWPGNLQSCQNKGDLAMEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKTLRNQLDMKHEEVEMLHQQIEEHEKAKQEMAMEYKQELLKLQEELGRLKRSYEKLQKRQLRDYRGNTKSLRDDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELTSQSEIQHLSSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQEHRQKEEKLRESEKLLEALQEEQKELKASLQSQENFILEEKIQKEKLQTKLKTVDTQHSVDSKRLLEDCQVERKYPSPGHGVFDNVLSQLDLSHTSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVQHKEILSQLESLKLENRRLSETVMKLELGLHEAKEISLTDLQENYIEALNKLVSENQQLQKDLMNTKSQLEHATHVCTKKDGRIFKPARSRVAEFKNAEFKPTHGQHRHDGIKTEQYKTGHHSPREQTLDSIEPMARGPSPMSPHTSPDSSTVSLPSNFLCYAHSLPSMLDINDGNFSDILSDCMNDQEEFVSSCTLPVSPLGSIATRFLEEEELRSHHILERLDAHIEELRRESERTVRQFTALV", "length": 757, "header": "tr|A0A9J7FVV9-1|A0A9J7FVV9_CRIGR Isoform 1 of Centrosomal protein of 63 kDa OS=Cricetulus griseus OX=10029 GN=Cep63 PE=3 SV=1 CANONICAL=A0A9J7FVV9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9/entry#A0A9J7FVV9-1", "sequence": { "sequence": "MQPDPLLFACGCPGTAPVGLSDYSMCSSVPASQTTAMTWWPGNLQSCQNKGDLAMEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKTLRNQLDMKHEEVEMLHQQIEEHEKAKQEMAMEYKQELLKLQEELGRLKRSYEKLQKRQLRDYRGNTKSLRDDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELTSQSEIQHLSSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQEHRQKEEKLRESEKLLEALQEEQKELKASLQSQENFILEEKIQKEKLQTKLKTVDTQHSVDSKRLLEDCQVERKYPSPGHGVFDNVLSQLDLSHTSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVQHKEILSQLESLKLENRRLSETVMKLELGLHEAKEISLTDLQENYIEALNKLVSENQQLQKDLMNTKSQLEHATHVCTKKDGRIFKPARSRVAEFKNAEFKPTHGQHRHDGIKTEQYKTGHHSPREQTLDSIEPMARGPSPMSPHTSPDSSTVSLPSNFLCYAHSLPSMLDINDGNFSDILSDCMNDQEEFVSSCTLPVSPLGSIATRFLEEEELRSHHILERLDAHIEELRRESERTVRQFTALV", "length": 757, "header": "tr|A0A9J7FVV9-1|A0A9J7FVV9_CRIGR Isoform 1 of Centrosomal protein of 63 kDa OS=Cricetulus griseus OX=10029 GN=Cep63 PE=3 SV=1 CANONICAL=A0A9J7FVV9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9/entry#A0A9J7FYU9-1", "sequence": { "sequence": "MQPDPLLFACGCPGTAPVGLSDYSMCSSVPASQTTAMTWWPGNLQSCQNKGDLAMEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKTLRNQLDMKHEEVEMLHQQIEEHEKAKQEMAMEYKQELLKLQEELGRLKRSYEKLQKRQLRDYRGNTKSLRDDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELTSQSEIQHLSSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQEHRQKEEKLRESEKLLEALQEEQKELKASLQSQENFILEEKIQKEKLQTKLKTVDTQHSVDSKRLLEDCQVERKYPSPGHGVFDNVLSQLDLSHTSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVQHKEILSQLESLKLENRRLSETVMKLELGLHECTLPVSPLGSIATRFLEEEELRSHHILERLDAHIEELRRESERTVRQFTALV", "length": 595, "header": "tr|A0A9J7FYU9-1|A0A9J7FYU9_CRIGR Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Cricetulus griseus OX=10029 GN=Cep63 PE=3 SV=1 CANONICAL=A0A9J7FVV9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9/entry#A0A9J7FYX8-1", "sequence": { "sequence": "MQPDPLLFACGCPGTAPVGLSDYSMCSSVPASQTTAMTWWPGNLQSCQNKGDLAMEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKTLRNQLDMKHEEVEMLHQQIEEHEKAKQEMAMEYKQELLKLQEELGRLKRSYEKLQKRQLRDYRGNTKSLRDDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELTSQSEIQHLSSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQEHRQKEEKLRESEKLLEALQEEQKELKASLQSQENFILEEKIQKEKLQTKLKTVDTQHSVDSKRLLEDCQVERKYPSPGHGVFDNVLSQLDLSHTSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVQHKEILSQLESLKLENRRLSETVMKLELGLHEVKCLKIEFSFSELLNFCLQKR", "length": 564, "header": "tr|A0A9J7FYX8-1|A0A9J7FYX8_CRIGR Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Cricetulus griseus OX=10029 GN=Cep63 PE=4 SV=1 CANONICAL=A0A9J7FVV9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G007-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9/entry#A0A9J7G007-1", "sequence": { "sequence": "MARGRCPSIPTCSRTLYCLPAAARAPHPWVSPTTPCAARCRPASCQNKGDLAMEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKTLRNQLDMKHEEVEMLHQQIEEHEKAKQEMAMEYKQELLKLQEELGRLKRSYEKLQKRQLRDYRGNTKSLRDDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELTSQSEIQHLSSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQEHRQKEEKLRESEKLLEALQEEQKELKASLQSQENFILEEKIQKEKLQTKLKTVDTQHSVDSKRLLEDCQVERKYPSPGHGVFDNVLSQLDLSHTSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVQHKEILSQLESLKLENRRLSETVMKLELGLHEAKEISLTDLQENYIEALNKLVSENQQLQKDLMNTKSQLEHATHVCTKKDGRIFKPARSRVAEFKNAEFKPTHGQHRHDGIKTEQYKTGHHSPREQTLDSIEPMARGPSPMSPHTSPDSSTVSLPSNFLCYAHSLPSMLDINDGNFSDILSDCMNDQEEFVSSCTLPVSPLGSIATRFLEEEELRSHHILERLDAHIEELRRESERTVRQFTALV", "length": 755, "header": "tr|A0A9J7G007-1|A0A9J7G007_CRIGR Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Cricetulus griseus OX=10029 GN=Cep63 PE=3 SV=1 CANONICAL=A0A9J7FVV9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9/entry#A0A9J7GVN8-1", "sequence": { "sequence": "MEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKTLRNQLDMKHEEVEMLHQQIEEHEKAKQEMAMEYKQELLKLQEELGRLKRSYEKLQKRQLRDYRGNTKSLRDDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELTSQSEIQHLSSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQEHRQKEEKLRESEKLLEALQEEQKELKASLQSQENFILEEKIQKEKLQTKLKTVDTQHSVDSKRLLEDCQVERKYPSPGHGVFDNVLSQLDLSHTSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVQHKEILSQLESLKLENRRLSETVMKLELGLHEAKEISLTDLQENYIEALNKLVSENQQLQKDLMNTKSQLEHATHVCTKKDGRIFKPARSRVAEFKNAEFKPTHGQHRHDGIKTEQYKTGHHSPREQTLDSIEPMARGPSPMSPHTSPDSSTVSLPSNFLCYAHSLPSMLDINDGNFSDILSDCMNDQEEFVSSCTLPVSPLGSIATRFLEEEELRSHHILERLDAHIEELRRESERTVRQFTALV", "length": 703, "header": "tr|A0A9J7GVN8-1|A0A9J7GVN8_CRIGR Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Cricetulus griseus OX=10029 GN=Cep63 PE=3 SV=1 CANONICAL=A0A9J7FVV9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9/entry#A0A9J7GWF7-1", "sequence": { "sequence": "MWTTAMTWWPGNLQSCQNKGDLAMEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKTLRNQLDMKHEEVEMLHQQIEEHEKAKQEMAMEYKQELLKLQEELGRLKRSYEKLQKRQLRDYRGNTKSLRDDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELTSQSEIQHLSSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQEHRQKEEKLRESEKLLEALQEEQKELKASLQSQENFILEEKIQKEKLQTKLKTVDTQHSVDSKRLLEDCQVERKYPSPGHGVFDNVLSQLDLSHTSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVQHKEILSQLESLKLENRRLSETVMKLELGLHEAKEISLTDLQENYIEALNKLVSENQQLQKDLMNTKSQLEHATHVCTKKDGRIFKPARSRVAEFKNAEFKPTHGQHRHDGIKTEQYKTGHHSPREQTLDSIEPMARGPSPMSPHTSPDSSTVSLPSNFLCYAHSLPSMLDINDGNFSDILSDCMNDQEEFVSSCTLPVSPLGSIATRFLEEEELRSHHILERLDAHIEELRRESERTVRQFTALV", "length": 726, "header": "tr|A0A9J7GWF7-1|A0A9J7GWF7_CRIGR Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Cricetulus griseus OX=10029 GN=Cep63 PE=3 SV=1 CANONICAL=A0A9J7FVV9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9/entry#A0A9J7JQI2-1", "sequence": { "sequence": "MQPDPLLFACGCPGTAPVGLSDYSMCSSVPASQTTAMTWWPGNLQSCQNKGDLAMEALLEGIQNRGHSGGFLTSCEAELQELMKQIDIMVAHKKSEWEGQTHALETCLDIRDRELKTLRNQLDMKHEEVEMLHQQIEEHEKAKQEMAMEYKQELLKLQEELGRLKRSYEKLQKRQLRDYRGNTKSLRDDRSEIERLTGKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELTSQSEIQHLSSKLERAKDTICANELEIERLNIRVNDLMGTNMTILQEHRQKEEKLRESEKLLEALQEEQKELKASLQSQENFILEEKIQKEKLQTKLKTVDTQHSVDSKRLLEDCQVERKYPSPGHGVFDNVLSQLDLSHTSEELLQAEVTRLEGSLESVSATCKQLSQELMEKYEELKRMEGHNNEYRTEIKKLKEQILQADQTYSSALEGMKMEISQLTRELHQRDITIASAKCSSSDMEKQLKAEMQKAEEKAVQHKEILSQLESLKLENRRLSETVMKLELGLHEAKEISLTDLQENYIEALNKLVSENQQLQKDLMNTKSQLEHATHVCTKKDGRIFKPARSRVAEFKNAEFNARCPSLLWDR", "length": 622, "header": "tr|A0A9J7JQI2-1|A0A9J7JQI2_CRIGR Computationally mapped isoform of Centrosomal protein of 63 kDa OS=Cricetulus griseus OX=10029 GN=Cep63 PE=4 SV=1 CANONICAL=A0A9J7FVV9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771874", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771874", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" } ], "pmid": "" }, { "name": "centriole replication", "id": "GO:0007099", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007099", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" } ], "pmid": "" }, { "name": "de novo centriole assembly involved in multi-ciliated epithelial cell differentiation", "id": "GO:0098535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098535", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FVV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" }, { "id": "PF25771", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25771" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CEP63/Deup1 CEP152 binding coiled coil", "eco_id": "ECO_0000259", "start_pos": 718, "end_pos": 753, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FVV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVV9" }, { "id": "PF17045", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17045" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CEP63/Deup1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 334, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 295, "end_pos": 297 }, { "start_pos": 687, "end_pos": 689 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVX7-1", "uniprot_ac": "A0A9J7FVX7", "uniprot_id": "A0A9J7FVX7_CRIGR", "mass": { "chemical_mass": 108767.0, "monoisotopic_mass": 108767.0 }, "refseq": { "ac": "XP_027267979", "name": "uncharacterized protein LOC113835292", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267979" }, "gene_names": [ { "name": "LOC113835292", "type": "recommended", "evidence": [ { "id": "A0A9J7FVX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" } ] }, { "name": "LOC113835292", "type": "synonym", "evidence": [ { "id": "XP_027267979", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267979" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC113835292", "type": "synonym", "evidence": [ { "id": "A0A9J7FVX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC113835292", "type": "synonym", "evidence": [ { "id": "XP_027267979", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267979" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276866.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267979" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113835292", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVX7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03715", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03715", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113835292", "url": "https://www.ncbi.nlm.nih.gov/gene/113835292", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113835292", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113835292", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVX7", "url": "https://www.orthodb.org/?gene=A0A9J7FVX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33064:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33064:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16721", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16721", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267979", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FVX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHSFLHVPDCPYPLLGRDLLTKLRAQIHFERSEVKVTGPEGIPLTILTMSIEDEYRLHEKRTNSNNQETLDHWLAEFPQAWAETGGMGLAINQAPIIVTLKAAILPASVRQYPMPKEAREGIRPHIKRLLEQGILVPCKSPWNTPLLPVRKPGTNDYRPVQDLREVNKRIEDIHPTVPNPYNLLSGLPPNYTWYTVLDLKDAFFCLRLHPTSQPIFAFEWQDADLGISGQLTWTRLPQGFKNSPTLFDEALHQDLAGFRVRYPALILLQYVDDILLAAKTKEECKEGTRALLQTLGSLGYRASAKKAQICQKQVTYLGYKIKDGRRWLTEARMRAILDIPTPQNPRQLREFLGTAGFCRLWIPGFAEMAAPLYPLTRPGVAFKWEEPQKKAFTNIKKALLESPALGLPDLAKPFELFIDEKGGYAKGVLTQKLGPWRRPTAYLSKKLDPVASGWPPCLRMIAAIALLVKDSYKLTLGQPLTIHAPHAVEAVIRQPPDRWLTNARMTHYQTMLLDKDRVHFGPLVTLNPATLLPLPGEPEAHNCLQVLAEAHGARPDLTDQPLPSPDHIWFTDGSSFLHQGKRRAGAAVTTENQVVWAQALPPGTSAQRAELIALTQALKLAEGKRLTVYTDSRYAFATAHIHGEIYRRRGLLTSEGKDIKNKEEILALLRALHLPSALSIIHCPGHQKGDSLEARGNRRADLAAREAALTTDTTSLLALEPTNDRPSPSWDYEQRDIQTLEKLGATKEPNGDWTYEGKTVIPYRVTKYLVTFLHKMTHLSSKKMRELLEREEEFNFLLGKNDILKQVTEQCDACARVNASRLKLPPGNRVRGYRPGTHWEIDFTEIKPAHLQALQLVQREIWKPLAQAYKDQRDHPTIPHSYQIGDTVWVRRHQAKNLEPHWKGPYIVLLTTPTALKVDGIAAWIHASHVKPARPTDSATTSEWTAHRTQNPLKIRLSRTPSC", "length": 963, "header": "tr|A0A9J7FVX7-1|A0A9J7FVX7_CRIGR Isoform 1 of Uncharacterized protein LOC113835292 OS=Cricetulus griseus OX=10029 GN=LOC113835292 PE=3 SV=1 CANONICAL=A0A9J7FVX7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7/entry#A0A9J7FVX7-1", "sequence": { "sequence": "MHSFLHVPDCPYPLLGRDLLTKLRAQIHFERSEVKVTGPEGIPLTILTMSIEDEYRLHEKRTNSNNQETLDHWLAEFPQAWAETGGMGLAINQAPIIVTLKAAILPASVRQYPMPKEAREGIRPHIKRLLEQGILVPCKSPWNTPLLPVRKPGTNDYRPVQDLREVNKRIEDIHPTVPNPYNLLSGLPPNYTWYTVLDLKDAFFCLRLHPTSQPIFAFEWQDADLGISGQLTWTRLPQGFKNSPTLFDEALHQDLAGFRVRYPALILLQYVDDILLAAKTKEECKEGTRALLQTLGSLGYRASAKKAQICQKQVTYLGYKIKDGRRWLTEARMRAILDIPTPQNPRQLREFLGTAGFCRLWIPGFAEMAAPLYPLTRPGVAFKWEEPQKKAFTNIKKALLESPALGLPDLAKPFELFIDEKGGYAKGVLTQKLGPWRRPTAYLSKKLDPVASGWPPCLRMIAAIALLVKDSYKLTLGQPLTIHAPHAVEAVIRQPPDRWLTNARMTHYQTMLLDKDRVHFGPLVTLNPATLLPLPGEPEAHNCLQVLAEAHGARPDLTDQPLPSPDHIWFTDGSSFLHQGKRRAGAAVTTENQVVWAQALPPGTSAQRAELIALTQALKLAEGKRLTVYTDSRYAFATAHIHGEIYRRRGLLTSEGKDIKNKEEILALLRALHLPSALSIIHCPGHQKGDSLEARGNRRADLAAREAALTTDTTSLLALEPTNDRPSPSWDYEQRDIQTLEKLGATKEPNGDWTYEGKTVIPYRVTKYLVTFLHKMTHLSSKKMRELLEREEEFNFLLGKNDILKQVTEQCDACARVNASRLKLPPGNRVRGYRPGTHWEIDFTEIKPAHLQALQLVQREIWKPLAQAYKDQRDHPTIPHSYQIGDTVWVRRHQAKNLEPHWKGPYIVLLTTPTALKVDGIAAWIHASHVKPARPTDSATTSEWTAHRTQNPLKIRLSRTPSC", "length": 963, "header": "tr|A0A9J7FVX7-1|A0A9J7FVX7_CRIGR Isoform 1 of Uncharacterized protein LOC113835292 OS=Cricetulus griseus OX=10029 GN=LOC113835292 PE=3 SV=1 CANONICAL=A0A9J7FVX7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:113835292", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113835292", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVX7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 818, "end_pos": 820, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FVX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" }, { "id": "PS50175", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50175" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 19, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FVX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 563, "end_pos": 709, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FVX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVX7" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 321, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 818, "end_pos": 820 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVY1-1", "uniprot_ac": "A0A9J7FVY1", "uniprot_id": "A0A9J7FVY1_CRIGR", "mass": { "chemical_mass": 150645.0, "monoisotopic_mass": 150645.0 }, "refseq": { "ac": "XP_016822282", "name": "nephrocystin-3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016822282" }, "gene_names": [ { "name": "Nphp3", "type": "recommended", "evidence": [ { "id": "A0A9J7FVY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ] }, { "name": "Nphp3", "type": "synonym", "evidence": [ { "id": "XP_016822282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016822282" } ] } ], "protein_names": [ { "name": "Nephrocystin-3", "type": "recommended", "evidence": [ { "id": "A0A9J7FVY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1/entry#names_and_taxonomy" } ] }, { "name": "nephrocystin-3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016822282", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016822282" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 330 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613657.1) and transcript sequence (IACG01029818.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016822282.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016822282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016822282" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nphp3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1", "locus": {} } ], "crossref": [ { "id": "100768113", "url": "https://www.ncbi.nlm.nih.gov/gene/100768113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768113", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768113", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVY1", "url": "https://www.orthodb.org/?gene=A0A9J7FVY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19871", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19871", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19871:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19871:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45641", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45641", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45641:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45641:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24885", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24885", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016822282", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016822282", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G030", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G030", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G030-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G030-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTASSLVSPAGGEVIEDTYGAGGGEACEIPVEVKPKARLLRSSFRRGAGAGPGSLPRAAGGGGLLGASFKSTGSSVPELEYAAAEFERLKKEYEIFRVSKNQELLSMGRREAKLDTENKRLRAELQALQKTYQKILREKEGALEAKYQAMERAVTFEHDRDRVKRQFKIFRETKENEIQDLLRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTATGTQCEYWASRALGSEPSIGSMIQLQQSFRGPEFAHSSIDVEGPFANINRDDWDTAVAGLLQVTPLFSHSLWSHSVRCYLMYTDETRPEMELFLKDHSPKLKRMCETMGYFFLAVYFPIDVENQYLTVRKWELEKSSLVILFLHSTLPSFLLEDCEEAFLQNPEGKPRLIYHHLEDENVTSDSVQQFLDQVSNLSKTNKAKIIHHSGDPAEGVYRTYISVEKIIKQDILGLEDTDVEVTDVGNEDSTPEEDDFGDVLWDIHDEQEQMEALQQASNSAHELGVEKYYQRLDDLVVAPAPIPPLLVSGGPGSGKSLLLSKWIRLQQKHFPNTLILSHFVGRPMSTSSEPSLIIKRLTLKLMQHFWAVSALTLDPAKLLEEFPHWLEKLSARHQGSVIIIIDSIDQVQQVEKHMKWLIDPLPVNVRVIVSVNVETCPAAWRLWPTLHLDPLSPKDAKSIIMAECHSVDMTLSREQEKQLDQHCRSATTCNALYTTLFSKMMACAGRAGNLEKTLRQCLECQDTVSLYRLVLRSIRESMPSEVDKELMTQILCLINVSHNGVSESELMELYPEMSWASMTSIVHSLHKMCLLTYSCGLLRFRHLQAWETVKLEYMEDPTLISSYRQKLINYFTSQLSQDRVTWRSADELPWLFQQQGSKQKLHDCLLNLLVSQNLYKRGHFAELLSYWQFVGKDKGAMATEYFESLKQYGNYEGEENMLCLADLYETLGRFLKDLGLLSQAVVPLQRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFADAEQLYKQALEISENAYGADHPQAARELEALATLYHKQNKYEQAEHFRKKSVIIRQQATRRKGSLYGFALLRRRALQLEELTLGKDKPENARTLNELGVLYYLQNNLETAEQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYEKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKTGRVDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLHSQMKKHSEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEEGNFEKAAELYKRAMEIKEAETSLLGGKAPSRQSSSGDTFIFKTTHSPNIFLPQGQR", "length": 1325, "header": "tr|A0A9J7FVY1-1|A0A9J7FVY1_CRIGR Isoform 1 of Nephrocystin-3 OS=Cricetulus griseus OX=10029 GN=Nphp3 PE=4 SV=1 CANONICAL=A0A9J7FVY1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1/entry#A0A9J7FVY1-1", "sequence": { "sequence": "MGTASSLVSPAGGEVIEDTYGAGGGEACEIPVEVKPKARLLRSSFRRGAGAGPGSLPRAAGGGGLLGASFKSTGSSVPELEYAAAEFERLKKEYEIFRVSKNQELLSMGRREAKLDTENKRLRAELQALQKTYQKILREKEGALEAKYQAMERAVTFEHDRDRVKRQFKIFRETKENEIQDLLRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTATGTQCEYWASRALGSEPSIGSMIQLQQSFRGPEFAHSSIDVEGPFANINRDDWDTAVAGLLQVTPLFSHSLWSHSVRCYLMYTDETRPEMELFLKDHSPKLKRMCETMGYFFLAVYFPIDVENQYLTVRKWELEKSSLVILFLHSTLPSFLLEDCEEAFLQNPEGKPRLIYHHLEDENVTSDSVQQFLDQVSNLSKTNKAKIIHHSGDPAEGVYRTYISVEKIIKQDILGLEDTDVEVTDVGNEDSTPEEDDFGDVLWDIHDEQEQMEALQQASNSAHELGVEKYYQRLDDLVVAPAPIPPLLVSGGPGSGKSLLLSKWIRLQQKHFPNTLILSHFVGRPMSTSSEPSLIIKRLTLKLMQHFWAVSALTLDPAKLLEEFPHWLEKLSARHQGSVIIIIDSIDQVQQVEKHMKWLIDPLPVNVRVIVSVNVETCPAAWRLWPTLHLDPLSPKDAKSIIMAECHSVDMTLSREQEKQLDQHCRSATTCNALYTTLFSKMMACAGRAGNLEKTLRQCLECQDTVSLYRLVLRSIRESMPSEVDKELMTQILCLINVSHNGVSESELMELYPEMSWASMTSIVHSLHKMCLLTYSCGLLRFRHLQAWETVKLEYMEDPTLISSYRQKLINYFTSQLSQDRVTWRSADELPWLFQQQGSKQKLHDCLLNLLVSQNLYKRGHFAELLSYWQFVGKDKGAMATEYFESLKQYGNYEGEENMLCLADLYETLGRFLKDLGLLSQAVVPLQRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFADAEQLYKQALEISENAYGADHPQAARELEALATLYHKQNKYEQAEHFRKKSVIIRQQATRRKGSLYGFALLRRRALQLEELTLGKDKPENARTLNELGVLYYLQNNLETAEQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYEKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKTGRVDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLHSQMKKHSEALPLYERALKIYEDSLGRMHPRVGETLKNLAVLSYEEGNFEKAAELYKRAMEIKEAETSLLGGKAPSRQSSSGDTFIFKTTHSPNIFLPQGQR", "length": 1325, "header": "tr|A0A9J7FVY1-1|A0A9J7FVY1_CRIGR Isoform 1 of Nephrocystin-3 OS=Cricetulus griseus OX=10029 GN=Nphp3 PE=4 SV=1 CANONICAL=A0A9J7FVY1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G030-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1/entry#A0A9J7G030-1", "sequence": { "sequence": "MGTASSLVSPAGGEVIEDTYGAGGGEACEIPVEVKPKARLLRSSFRRGAGAGPGSLPRAAGGGGLLGASFKSTGSSVPELEYAAAEFERLKKEYEIFRVSKNQELLSMGRREAKLDTENKRLRAELQALQKTYQKILREKEGALEAKYQAMERAVTFEHDRDRVKRQFKIFRETKENEIQDLLRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTATGTQCEYWASRALGSEPSIGSMIQLQQSFRGPEFAHSSIDVEGPFANINRDDWDTAVAGLLQVTPLFSHSLWSHSVRCYLMYTDETRPEMELFLKDHSPKLKRMCETMGYFFLAVYFPIDVENQYLTVRKWELEKSSLVILFLHSTLPSFLLEDCEEAFLQNPEGKPRLIYHHLEDENVTSDSVQQFLDQVSNLSKTNKAKIIHHSGDPAEGVYRTYISVEKIIKQDILGLEDTDVEVTDVGNEDSTPEEDDFGDVLWDIHDEQEQMEALQQASNSAHELGVEKYYQRLDDLVVAPAPIPPLLVSGGPGSGKSLLLSKWIRLQQKHFPNTLILSHFVGRPMSTSSEPSLIIKRLTLKLMQHFWAVSALTLDPAKLLEEFPHWLEKLSARHQGSVIIIIDSIDQVQQVEKHMKWLIDPLPVNVRVIVSVNVETCPAAWRLWPTLHLDPLSPKDAKSIIMAECHSVDMTLSREQEKQLDQHCRSATTCNALYTTLFSKMMA", "length": 719, "header": "tr|A0A9J7G030-1|A0A9J7G030_CRIGR Computationally mapped isoform of Nephrocystin-3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Nphp3 PE=4 SV=1 CANONICAL=A0A9J7FVY1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1/entry#A0A9J7JXL8-1", "sequence": { "sequence": "MGTASSLVSPAGGEVIEDTYGAGGGEACEIPVEVKPKARLLRSSFRRGAGAGPGSLPRAAGGGGLLGASFKSTGSSVPELEYAAAEFERLKKEYEIFRVSKNQELLSMGRREAKLDTENKRLRAELQALQKTYQKILREKEGALEAKYQAMERAVTFEHDRDRVKRQFKIFRETKENEIQDLLRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTATGTQCEYWASRALGSEPSIGSMIQLQQSFRGPEFAHSSIDVEGPFANINRDDWDTAVAGLLQVTPLFSHSLWSHSVRCYLMYTDETRPEMELFLKDHSPKLKRMCETMGYFFLAVYFPIDVENQYLTVRKWELEKSSLVILFLHSTLPSFLLEDCEEAFLQNPEGKPRLIYHHLEDENVTSDSVQQFLDQVSNLSKTNKAKIIHHSGDPAEGVYRTYISVEKIIKQDILGLEDTDVEVTDVGNEDSTPEEDDFGDVLWDIHDEQEQMEALQQASNSAHELGVEKYYQRLDDLVVAPAPIPPLLVSGGPGSGKSLLLSKWIRLQQKHFPNTLILSHFVGRPMSTSSEPSLIIKRLTLKLMQHFWAVSALTLDPAKLLEEFPHWLEKLSARHQGSVIIIIDSIDQVQQVEKHMKWLIDPLPVNVRVIVSVNVETCPAAWRLWPTLHLDPLSPKDAKSIIMAECHSVDMTLSREQEKQLDQHCRSATTCNALYTTLFSKMMACAGRAGNLEKTLRQCLECQDTVSLYRLVLRSIRESMPSEVDKELMTQILCLINVSHNGVSESELMELYPEMSWASMTSIVHSLHKMCLLTYSCGLLRFRHLQAWETVKLEYMEDPTLISSYRQKLINYFTSQLSQDRVTWRSADELPWLFQQQGSKQKLHDCLLNLLVSQNLYKRGHFAELLSYWQFVGKDKGAMATEYFESLKQYGNYEGEENMLCLADLYETLGRFLKDLGLLSQAVVPLQRSLEIRETALDPDHPRVAQSLHQLASVYVQWKKFADAEQLYKQALEISENAYGADHPQAARELEALATLYHKQNKYEQAEHFRKKSVIIRQQATRRKGSLYGFALLRRRALQLEELTLGKDKPENARTLNELGVLYYLQNNLETAEQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYEKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKTIILLFFREELTRLYLYMNWLLKFGRNPLAQNTPV", "length": 1219, "header": "tr|A0A9J7JXL8-1|A0A9J7JXL8_CRIGR Computationally mapped isoform of Nephrocystin-3 OS=Cricetulus griseus OX=10029 GN=Nphp3 PE=4 SV=1 CANONICAL=A0A9J7FVY1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768113", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768113", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "kidney morphogenesis", "id": "GO:0060993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060993", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ], "pmid": "" }, { "name": "maintenance of animal organ identity", "id": "GO:0048496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048496", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ], "pmid": "" }, { "name": "determination of left/right symmetry", "id": "GO:0007368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007368", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ], "pmid": "" }, { "name": "convergent extension", "id": "GO:0060026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060026", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ciliary base", "id": "GO:0097546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097546", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ], "pmid": "" }, { "name": "ciliary inversin compartment", "id": "GO:0097543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097543", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FVY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" }, { "id": "PF24884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nephrocystin 3 helical", "eco_id": "ECO_0000259", "start_pos": 671, "end_pos": 830, "start_aa": "Lys", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FVY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" }, { "id": "PF24883", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24883" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nephrocystin 3-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 522, "end_pos": 646, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FVY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" }, { "id": "PF24885", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24885" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nephrocystin-3 TPR-repeats region", "eco_id": "ECO_0000259", "start_pos": 841, "end_pos": 1078, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FVY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVY1" }, { "id": "PF25022", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nephrocystin-3 alpha-beta", "eco_id": "ECO_0000259", "start_pos": 291, "end_pos": 450, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 398, "end_pos": 400 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 772, "end_pos": 774 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FVZ5-1", "uniprot_ac": "A0A9J7FVZ5", "uniprot_id": "A0A9J7FVZ5_CRIGR", "mass": { "chemical_mass": 76224.0, "monoisotopic_mass": 76224.0 }, "refseq": { "ac": "XP_027267860", "name": "BUD13 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267860" }, "gene_names": [ { "name": "Bud13", "type": "recommended", "evidence": [ { "id": "A0A9J7FVZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVZ5" } ] }, { "name": "Bud13", "type": "synonym", "evidence": [ { "id": "XP_027267860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267860" } ] } ], "protein_names": [ { "name": "BUD13 homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7FVZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVZ5/entry#names_and_taxonomy" } ] }, { "name": "BUD13 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027267860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267860" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267860" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVZ5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bud13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVZ5", "locus": {} } ], "crossref": [ { "id": "A0A9J7FVZ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FVZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100773647", "url": "https://www.ncbi.nlm.nih.gov/gene/100773647", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773647", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773647", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FVZ5", "url": "https://www.orthodb.org/?gene=A0A9J7FVZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31809:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31809:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FVZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FVZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAALPLSKAEYLKRYLSGADAGPEGGPESVRKRRRKRPKPGGAGGKGMRIVDDDVGWAAISTTKPEKEEEEDGDLPVVAEFVDERPEEVKQMEAFRSSAKWRLLGDHSEDGHFHHDDQDPSPPRRVHRDTPDPSSPRRAHHDTPDPSPRRTCHDTPDPSPRRAHHDTPDPSPPRRAHHDTPDPSPRRARNDTPDPSPRRARNDTPDPSPRKARHDTPDPSPPRRARNDTPDPSPPRRARHDTPDPSPPRRSRHDSDTSPPRRVHHDSATSPPRKSHRNSSSVSPRRGHHGSSDISSPRRAHNHSPDTPQHRRTVDPSDPQHLRRPRHDSPDLELPRTKSSKAAERSCNKTVHQRGQEPSHPSVSKNSKYGRDSDLSPRKWQAKAHVGAKKQLDPKGVCQKSSDSDLSPPRQKQNSGHQDSDSDLSPPRNRQRHRSADSDLSPPRRRQRTKSSDSDLSPPRRSPRPGKKAAHMYSGAKTGLVTDVQREHQELKKQDQDTTTLGAQFEFAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKQKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKAVEELAYKWSVEDM", "length": 669, "header": "tr|A0A9J7FVZ5-1|A0A9J7FVZ5_CRIGR Isoform 1 of BUD13 homolog OS=Cricetulus griseus OX=10029 GN=Bud13 PE=3 SV=1 CANONICAL=A0A9J7FVZ5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FVZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVZ5/entry#A0A9J7FVZ5-1", "sequence": { "sequence": "MAAALPLSKAEYLKRYLSGADAGPEGGPESVRKRRRKRPKPGGAGGKGMRIVDDDVGWAAISTTKPEKEEEEDGDLPVVAEFVDERPEEVKQMEAFRSSAKWRLLGDHSEDGHFHHDDQDPSPPRRVHRDTPDPSSPRRAHHDTPDPSPRRTCHDTPDPSPRRAHHDTPDPSPPRRAHHDTPDPSPRRARNDTPDPSPRRARNDTPDPSPRKARHDTPDPSPPRRARNDTPDPSPPRRARHDTPDPSPPRRSRHDSDTSPPRRVHHDSATSPPRKSHRNSSSVSPRRGHHGSSDISSPRRAHNHSPDTPQHRRTVDPSDPQHLRRPRHDSPDLELPRTKSSKAAERSCNKTVHQRGQEPSHPSVSKNSKYGRDSDLSPRKWQAKAHVGAKKQLDPKGVCQKSSDSDLSPPRQKQNSGHQDSDSDLSPPRNRQRHRSADSDLSPPRRRQRTKSSDSDLSPPRRSPRPGKKAAHMYSGAKTGLVTDVQREHQELKKQDQDTTTLGAQFEFAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLREQEREGDPMANFIKKNKAKENKQKKVRPRYSGPAPPPNRFNIWPGYRWDGVDRSNGFEQKRFARLASKKAVEELAYKWSVEDM", "length": 669, "header": "tr|A0A9J7FVZ5-1|A0A9J7FVZ5_CRIGR Isoform 1 of BUD13 homolog OS=Cricetulus griseus OX=10029 GN=Bud13 PE=3 SV=1 CANONICAL=A0A9J7FVZ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "RES complex", "id": "GO:0070274", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070274", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVZ5" } ], "pmid": "" }, { "name": "U2-type spliceosomal complex", "id": "GO:0005684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005684", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FVZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FW05-1", "uniprot_ac": "A0A9J7FW05", "uniprot_id": "A0A9J7FW05_CRIGR", "mass": { "chemical_mass": 20940.0, "monoisotopic_mass": 20940.0 }, "refseq": { "ac": "XP_003496720", "name": "putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496720" }, "gene_names": [ { "name": "Urad", "type": "recommended", "evidence": [ { "id": "A0A9J7FW05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05" } ] }, { "name": "Urad", "type": "synonym", "evidence": [ { "id": "XP_003496720", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496720" } ] } ], "protein_names": [ { "name": "2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "type": "recommended", "evidence": [ { "id": "A0A9J7FW05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05/entry#names_and_taxonomy" } ] }, { "name": "4.1.1.97", "type": "synonym", "evidence": [ { "id": "A0A9J7FW05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05/entry#names_and_taxonomy" } ] }, { "name": "Parahox neighbor", "type": "synonym", "evidence": [ { "id": "A0A9J7FW05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05/entry#names_and_taxonomy" } ] }, { "name": "Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase", "type": "synonym", "evidence": [ { "id": "A0A9J7FW05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05/entry#names_and_taxonomy" } ] }, { "name": "putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "type": "synonym", "evidence": [ { "id": "XP_003496720", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496720" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613630.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003496720.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003496720", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496720" } ] }, { "annotation": "Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05#function" }, { "database": "UniProtKB", "id": "ARBA00002506", "url": "https://www.uniprot.org/uniprotkb/ARBA00002506#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Urad", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05", "locus": {} } ], "crossref": [ { "id": "A0A9J7FW05", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FW05", "database": "AlphaFoldDB", "categories": [] }, { "id": "100762187", "url": "https://www.ncbi.nlm.nih.gov/gene/100762187", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762187", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762187", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCQNERA", "url": "https://omabrowser.org/oma/group/RCQNERA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FW05", "url": "https://www.orthodb.org/?gene=A0A9J7FW05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43466", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43466", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43466:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43466:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09349", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09349", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003496720", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496720", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "26301", "url": "https://www.rhea-db.org/rhea/26301", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FW05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW05-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDMEKVNSMGFREFVDVFGNIIEKCPLVAAAVWSQRPFSDLQDLENHFFAFIDALPRSGQEGILRCHPDLAGRDLQQGTLTAESQREQSQAGLTSLDADDRLRLQQLNARYRERFGFPFVLAARLSDRDAVPRELARRLHCQPESELRTALGEVKKIGHLRLADLLGADPARVEPPRSWRSERQ", "length": 184, "header": "tr|A0A9J7FW05-1|A0A9J7FW05_CRIGR Isoform 1 of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase OS=Cricetulus griseus OX=10029 GN=Urad PE=3 SV=1 CANONICAL=A0A9J7FW05-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FW05-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05/entry#A0A9J7FW05-1", "sequence": { "sequence": "MDMEKVNSMGFREFVDVFGNIIEKCPLVAAAVWSQRPFSDLQDLENHFFAFIDALPRSGQEGILRCHPDLAGRDLQQGTLTAESQREQSQAGLTSLDADDRLRLQQLNARYRERFGFPFVLAARLSDRDAVPRELARRLHCQPESELRTALGEVKKIGHLRLADLLGADPARVEPPRSWRSERQ", "length": 184, "header": "tr|A0A9J7FW05-1|A0A9J7FW05_CRIGR Isoform 1 of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase OS=Cricetulus griseus OX=10029 GN=Urad PE=3 SV=1 CANONICAL=A0A9J7FW05-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762187", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762187", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1L259-1", "protein_name": "2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "gene_name": "urad", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDINVVNALAYEDFVKLFGNVVEKCPLISAAIWSYRPFKDLADIEARISEFIHSLPDSGKEGILRCHPDLAGRDLQSGTLTPESQEEQSQAGMTTLDSAEIVHMYRLNSEYKERFGFPFVICARLNNKADIVRQLSERLKNRRTAELECAIEEVKKICSLRLHSIVLSDIQTKL", "length": 174 }, "evidence": [ { "id": "A0A9J7FW05", "url": "https://omabrowser.org/oma/group/A0A9J7FW05/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NGE7-1", "protein_name": "Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "gene_name": "URAD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDIEKVNSMDLGEFVDVFGNATERCPLIAAAVWSQRPFSDLEDLEKHFFAFIDALAQSGQEGILRCHPDLAGSELQRGTLTAESQREQSGAGLRSLGADERLRLAELNAQYRARFGFPFVLAARFSDRTAVPRELARRLLCPSAQELRTALGEVKKIGSLRLADLLRADPAKL", "length": 173 }, "evidence": [ { "id": "A0A9J7FW05", "url": "https://omabrowser.org/oma/group/A0A9J7FW05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1MIY5-1", "protein_name": "2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "gene_name": "URAD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDIEKVNSMDFGEFVDVFGNVIERCPLIAAAVWSKRPFSGLGDLEKHFFAFIDGLPLSGQEGVLRCHPELAGRQLPWGRLTAESQREQSAAGLQNLGAAERLRFTELTAQYRTRFGFPFVLAVRLSDPAAAPRELARRLRCPPAQELRTALGEVKKICHLRLADLLGEQP", "length": 170 }, "evidence": [ { "id": "A0A9J7FW05", "url": "https://omabrowser.org/oma/group/A0A9J7FW05/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0RCU5-1", "protein_name": "2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "gene_name": "Urad", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDMKKVNSLDFTEFVSVFRNVVERCPLVAAAVWSHRPFSGLEDLENHFFAFIDALPKSGQEGILRCHPDLAGRDVLMGRLSEESRREQSHAGLTSLKTHDRLRLLHLNQEYRKRFGFPFVVAALLSDRATVFQELARRLHCQPESELRTALDEVKKIIHLRLIDLLDSHYFGVEPPQGRGLERRQDASERGDSAPQASSDLEDDPHTHTKEVEN", "length": 214 }, "evidence": [ { "id": "A0A9J7FW05", "url": "https://omabrowser.org/oma/group/A0A9J7FW05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q283N4-1", "protein_name": "2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "gene_name": "Urad", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDMVKVNSMDFGEFVDVFGNIVEKCPLIAAAVWSQRPFSGLEDLENHFFAFIDALPRSGQEGILRCHPDLAGRDLQQGTLTAESQREQSQAGLTSLDTDDRLRLQQLNAQYRERFGFPFVLAARLSDRATVPRELARRLQCQPESELRTALGEVKKISHLRLTDLLGAHSHSARVELP", "length": 178 }, "evidence": [ { "id": "A0A9J7FW05", "url": "https://omabrowser.org/oma/group/A0A9J7FW05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "urate catabolic process", "id": "GO:0019628", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019628", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05" } ], "pmid": "" }, { "name": "purine nucleobase metabolic process", "id": "GO:0006144", "url": 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"A0A9J7FW05", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "26301", "name": "", "equation": "5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) = (S)-allantoin + CO2", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7FW05-1" ], "evidence": [ { "id": "26301", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/26301" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7FW05", "gene_name": "Urad", "activity": [ { "ec_number": "4.1.1.97", "activity": "5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) = (S)-allantoin + CO2.", "evidence": [ { "id": "A0A9J7FW05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05" } ] }, { "ec_number": "4.1.1.97", "activity": "", "evidence": [ { "id": "A0A9J7FW05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FW05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW05" }, { "id": "PF09349", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09349" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 163, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.1.1.97", "ec_name": "5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) = (S)-allantoin + CO2.", "evidence": [ { "id": "4.1.1.97", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.1.1.97" }, { "id": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC9" } ] }, { "name": "Sumf2", "type": "synonym", "evidence": [ { "id": "XP_007648259", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648259" } ] } ], "protein_names": [ { "name": "Inactive C-alpha-formylglycine-generating enzyme 2", "type": "recommended", "evidence": [ { "id": "A0A9J7FWC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC9/entry#names_and_taxonomy" } ] }, { "name": "Sulfatase-modifying factor 2", "type": "synonym", "evidence": [ { "id": "A0A9J7FWC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC9/entry#names_and_taxonomy" } ] }, { "name": "inactive C-alpha-formylglycine-generating enzyme 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007648259", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648259" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614718.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007648259", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648259" } ] }, { "annotation": "Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. 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"MGSSLPVLSLMCLLSSPRLQLGNAQAPTMVQLPGGRFLMGTDAPDGRDGEGPAREVTVKSFTIDVFPVTNKDFREFVREKKYQTEAETFGWSFVFEDFVSPELRNQANQMPSVLWWLPVQKAFWRQPAGPGSGIREKLELPVVHVSWNDASAYCAWRGKRLPTEEEWEFAARGGLKGQVYPWGNRFQPNRTNLWQGKFPKGDRAEDGFHGLSPVNAFPPQNNYGLYDLMGNVWEWTASIYQSASQDMRVLRGASWIDTADGSANHRARVTTRFLDESNKNSTVLELSRDGGPRSPGAVS", "length": 299, "header": "tr|A0A9J7G0I6-1|A0A9J7G0I6_CRIGR Computationally mapped isoform of Inactive C-alpha-formylglycine-generating enzyme 2 OS=Cricetulus griseus OX=10029 GN=Sumf2 PE=3 SV=1 CANONICAL=A0A9J7FWC9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270233" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dock3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6", "locus": {} } ], "crossref": [ { "id": "cd08695", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08695", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11704", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11704", "database": "CDD", 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768911", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768911", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FWL6", "url": "https://www.orthodb.org/?gene=A0A9J7FWL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45653", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45653", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45653:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45653:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16172", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16172", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23554", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23554", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270233", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270233", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FW20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW20-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXT4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ17-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G074", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G074-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G074-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQL0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGIFPANYIHLKKAVVSNRGQYETVVPLEDSIVTEVTTTLQEWASLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGESCRMPVPHHFFFSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPAHLHYRRPYGCAVLSILDVLQSLTELKEEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYSAPSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMCDTHYQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVESELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGVSFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYECLYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYISKHPGDAEKIAQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPMSPENIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNMVMMGDSSMGEAPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLSSTHSAPSQMITSAPSSTRGSPSLPDKYRHAREMMLLLPTHRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSMAEKAVPAAPSSWSLDSGAQEAQPFLSALMGHILAPPVPPRSLLHGHYSLHFDAFHHPLGDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEAPPRTDTMDSMPSQAWNGDEDLEPPYLPVHYSLSESAVLDSIKSQPCRSHSAPGCVIPQDPMDPPALPPKPYHPRLPALEHDEGMLLREEAERPRGLHRKASLPPGSAKEEQARMAWEHGRGEQ", "length": 2071, "header": "tr|A0A9J7FWL6-1|A0A9J7FWL6_CRIGR Isoform 1 of Dedicator of cytokinesis protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dock3 PE=3 SV=1 CANONICAL=A0A9J7FWL6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FW20-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6/entry#A0A9J7FW20-1", "sequence": { "sequence": "MWTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGIFPANYIHLKKAVVSNRGQYETVVPLEDSIVTEVTTTLQEWASLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGESCRMPVPHHFFFSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPAHLHYRRPYGCAVLSILDVLQSLTELKEEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYSAPSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMCDTHYQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVESELIDKLDSMVSEGKGDESYRELFSLLLLEKVEQETWRETGVSFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYECLYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYISKHPGDAEKIAQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPMSPENIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNMVMMGDSSMGEAPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLSSTHSAPSQMITSAPSSTRGSPSLPDKYRHAREMMLLLPTHRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSMAEKAVPAAPSSWSLDSGAQEAQPFLSALMGHILAPPVPPRSLLHGHYSLHFDAFHHPLGDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEAPPRTDTMDSMPSQAWNGDEDLEPPYLPVHYSLSESAVLDSIKSQPCRSHSAPGCVIPQDPMDPPALPPKPYHPRLPALEHDEGMLLREEAERPRGLHRKASLPPGSAKEEQARMAWEHGRGEQ", "length": 2062, "header": "tr|A0A9J7FW20-1|A0A9J7FWL6_CRIGR Computationally mapped isoform of Dedicator of cytokinesis protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dock3 PE=3 SV=1 CANONICAL=A0A9J7FWL6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6/entry#A0A9J7FWL6-1", "sequence": { "sequence": "MWTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGIFPANYIHLKKAVVSNRGQYETVVPLEDSIVTEVTTTLQEWASLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGESCRMPVPHHFFFSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPAHLHYRRPYGCAVLSILDVLQSLTELKEEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYSAPSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMCDTHYQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVESELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGVSFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYECLYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYISKHPGDAEKIAQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPMSPENIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNMVMMGDSSMGEAPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLSSTHSAPSQMITSAPSSTRGSPSLPDKYRHAREMMLLLPTHRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSMAEKAVPAAPSSWSLDSGAQEAQPFLSALMGHILAPPVPPRSLLHGHYSLHFDAFHHPLGDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEAPPRTDTMDSMPSQAWNGDEDLEPPYLPVHYSLSESAVLDSIKSQPCRSHSAPGCVIPQDPMDPPALPPKPYHPRLPALEHDEGMLLREEAERPRGLHRKASLPPGSAKEEQARMAWEHGRGEQ", "length": 2071, "header": "tr|A0A9J7FWL6-1|A0A9J7FWL6_CRIGR Isoform 1 of Dedicator of cytokinesis protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dock3 PE=3 SV=1 CANONICAL=A0A9J7FWL6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6/entry#A0A9J7FXT4-1", "sequence": { "sequence": "MWTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGIFPANYIHLKKAVVSNRGQYETVVPLEDSIVTEVTTTLQEWASLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGESCRMPVPHHFFFSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPAHLHYRRPYGCAVLSILDVLQSLTELKEEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYSAPSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMCDTHYQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVESELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGVSFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYECLYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYISKHPGDAEKIAQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPMSPENIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNMVMMGDSSMGEAPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLSSTHSAPSQMITSAPSSTRDKYRHAREMMLLLPTHRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSMAEKAVPAAPSSWSLDSGAQEAQPFLSALMGHILAPPVPPRSLLHGHYSLHFDAFHHPLGDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEAPPRTDTMDSMPSQAWNGDEDLEPPYLPVHYSLSESAVLDSIKSQPCRSHSAPGCVIPQDPMDPPALPPKPYHPRLPALEHDEGMLLREEAERPRGLHRKASLPPGSAKEEQARMAWEHGRGEQ", "length": 2065, "header": "tr|A0A9J7FXT4-1|A0A9J7FXT4_CRIGR Computationally mapped isoform of Dedicator of cytokinesis protein 3 isoform X3 OS=Cricetulus griseus OX=10029 GN=Dock3 PE=3 SV=1 CANONICAL=A0A9J7FWL6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZ17-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6/entry#A0A9J7FZ17-1", "sequence": { "sequence": "MKRDLYIVAHVIRIGRMLLNDSKKGPAHLHYRRPYGCAVLSILDVLQSLTELKEEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYSAPSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMCDTHYQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVESELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGVSFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYECLYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYISKHPGDAEKIAQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPMSPENIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNMVMMGDSSMGEAPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLSSTHSAPSQMITSAPSSTRGSPSLPDKYRHAREMMLLLPTHRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSMAEKAVPAAPSSWSLDSGAQEAQPFLSALMGHILAPPVPPRSLLHGHYSLHFDAFHHPLGDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEAPPRTDTMDSMPSQAWNGDEDLEPPYLPVHYSLSESAVLDSIKSQPCRSHSAPGCVIPQDPMDPPALPPKPYHPRLPALEHDEGMLLREEAERPRGLHRKASLPPGSAKEEQARMAWEHGRGEQ", "length": 1789, "header": "tr|A0A9J7FZ17-1|A0A9J7FZ17_CRIGR Computationally mapped isoform of Dedicator of cytokinesis protein 3 isoform X8 OS=Cricetulus griseus OX=10029 GN=Dock3 PE=3 SV=1 CANONICAL=A0A9J7FWL6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G074-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6/entry#A0A9J7G074-1", "sequence": { "sequence": "MWTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGIFPANYIHLKKAVVSNRGQYETVVPLEDSIVTEVTTTLQEWASLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGESCRMPVPHHFFFSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPAHLHYRRPYGCAVLSILDVLQSLTELKEEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYSAPSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAGEYVSCLLSLLRQMCDTHYQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVESELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGVSFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYECLYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYISKHPGDAEKIAQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPMSPENIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNMVMMGDSSMGEAPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLSSTHSAPSQMITSAPSSTRGSPSLPDKYRHAREMMLLLPTHRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSMAEKAVPAAPSSWSLDSGAQEAQPFLSALMGHILAPPVPPRSLLHGHYSLHFDAFHHPLGDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEAPPRTDTMDSMPSQAWNGDEDLEPPYLPVHYSLSESAVLDSIKSQPCRSHSAPGCVIPQDPMDPPALPPKPYHPRLPALEHDEGMLLREEAERPRGLHRKASLPPGSAKEEQARMAWEHGRGEQ", "length": 2057, "header": "tr|A0A9J7G074-1|A0A9J7G074_CRIGR Computationally mapped isoform of Dedicator of cytokinesis protein 3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Dock3 PE=3 SV=1 CANONICAL=A0A9J7FWL6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6/entry#A0A9J7GXP5-1", "sequence": { "sequence": "MWHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGESCRMPVPHHFFFSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPAHLHYRRPYGCAVLSILDVLQSLTELKEEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYSAPSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLSLLRQMCDTHYQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVESELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGVSFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYECLYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYISKHPGDAEKIAQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPMSPENIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNMVMMGDSSMGEAPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLSSTHSAPSQMITSAPSSTRGSPSLPDKYRHAREMMLLLPTHRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSMAEKAVPAAPSSWSLDSGAQEAQPFLSALMGHILAPPVPPRSLLHGHYSLHFDAFHHPLGDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEAPPRTDTMDSMPSQAWNGDEDLEPPYLPVHYSLSESAVLDSIKSQPCRSHSAPGCVIPQDPMDPPALPPKPYHPRLPALEHDEGMLLREEAERPRGLHRKASLPPGSAKEEQARMAWEHGRGEQ", "length": 1918, "header": "tr|A0A9J7GXP5-1|A0A9J7GXP5_CRIGR Computationally mapped isoform of Dedicator of cytokinesis protein 3 isoform X7 OS=Cricetulus griseus OX=10029 GN=Dock3 PE=3 SV=1 CANONICAL=A0A9J7FWL6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6/entry#A0A9J7JQL0-1", "sequence": { "sequence": "MWTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGIFPANYIHLKKAVVSNRGQYETVVPLEDSIVTEVTTTLQEWASLWKQLYVKHKVDLFYKLRHVMNELIDLRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGESCRMPVPHHFFFSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPAHLHYRRPYGCAVLSILDVLQSLTELKEEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYSAPSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGEIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLGEYVSCLLSLLRQMCDTHYQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVESELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGVSFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYECLYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYISKHPGDAEKIAQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPMSPENIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNMVMMGDSSMGEAPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLSSTHSAPSQMITSAPSSTRGSPSLPDKYRHAREMMLLLPTHRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSMAEKAVPAAPSSWSLDSGAQEAQPFLSALMGHILAPPVPPRSLLHGHYSLHFDAFHHPLGDAPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEAPPRTDTMDSMPSQAWNGDEDLEPPYLPVHYSLSESAVLDSIKSQPCRSHSAPGCVIPQDPMDPPALPPKPYHPRLPALEHDEGMLLREEAERPRGLHRKASLPPGSAKEEQARMAWEHGRGEQ", "length": 2022, "header": "tr|A0A9J7JQL0-1|A0A9J7JQL0_CRIGR Computationally mapped isoform of Dedicator of cytokinesis protein 3 isoform X6 OS=Cricetulus griseus OX=10029 GN=Dock3 PE=3 SV=1 CANONICAL=A0A9J7FWL6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW20" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW20" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768911", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768911", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" } ], "pmid": "" }, { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1253, "end_pos": 1255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1729, "end_pos": 1731, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1827, "end_pos": 1829, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1923, "end_pos": 1925, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FWL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" }, { "id": "PS51650", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51650" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 DOCK-type", "eco_id": "ECO_0000259", "start_pos": 421, "end_pos": 599, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FWL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" }, { "id": "PS51651", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51651" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOCKER", "eco_id": "ECO_0000259", "start_pos": 1228, "end_pos": 1635, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FWL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWL6" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 67, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1022, "end_pos": 1024 }, { 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268092", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268092" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113835308", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40", "locus": {} } ], "crossref": [ { "id": "A0A9J7FW40", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FW40", "database": "AlphaFoldDB", "categories": [] }, { "id": "113835308", "url": "https://www.ncbi.nlm.nih.gov/gene/113835308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113835308", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113835308", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FW40", "url": "https://www.orthodb.org/?gene=A0A9J7FW40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268092", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268092", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FW40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEGNHSRVTEFILTGLTNKPELKLPLFLLFLGIYLLTVLGNLGMIILILLSSHLHTPMYFFLSSLSFIDLCYSTVITPKMLVNFVKEKNVISYQECMTQLYFFLAFVISECHMLSAMAYDRYVAICNPLLYNVTMSYQVCSWVIGMVYGIGIIEATVHTACMLQVHFCNVNVVNHYFCDLLPLLQLSCSSTFVNEVVLLCLSTFNFCVPTLTILSSYSFIIARIVRMKSTESRFKAFSTCSSHISAVAIFFGSLGFMYLQPSSIHSNNQGKVSSVFYTTVVPMLNPLIYSLRNKDVKLALNKLLQKRTFHM", "length": 312, "header": "tr|A0A9J7FW40-1|A0A9J7FW40_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC113835308 PE=3 SV=1 CANONICAL=A0A9J7FW40-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FW40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40/entry#A0A9J7FW40-1", "sequence": { "sequence": "MSEGNHSRVTEFILTGLTNKPELKLPLFLLFLGIYLLTVLGNLGMIILILLSSHLHTPMYFFLSSLSFIDLCYSTVITPKMLVNFVKEKNVISYQECMTQLYFFLAFVISECHMLSAMAYDRYVAICNPLLYNVTMSYQVCSWVIGMVYGIGIIEATVHTACMLQVHFCNVNVVNHYFCDLLPLLQLSCSSTFVNEVVLLCLSTFNFCVPTLTILSSYSFIIARIVRMKSTESRFKAFSTCSSHISAVAIFFGSLGFMYLQPSSIHSNNQGKVSSVFYTTVVPMLNPLIYSLRNKDVKLALNKLLQKRTFHM", "length": 312, "header": "tr|A0A9J7FW40-1|A0A9J7FW40_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC113835308 PE=3 SV=1 CANONICAL=A0A9J7FW40-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113835308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113835308", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FW40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW40" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FW56-1", "uniprot_ac": "A0A9J7FW56", "uniprot_id": "A0A9J7FW56_CRIGR", "mass": { "chemical_mass": 68941.0, "monoisotopic_mass": 68941.0 }, "refseq": { "ac": "XP_027270304", "name": "vacuolar fusion protein MON1 homolog A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270304" }, "gene_names": [ { "name": "Mon1a", "type": "recommended", "evidence": [ { "id": "A0A9J7FW56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW56" } ] }, { "name": "Mon1a", "type": "synonym", "evidence": [ { "id": "XP_027270304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270304" } ] } ], "protein_names": [ { "name": "Vacuolar fusion protein MON1 homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7FW56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW56/entry#names_and_taxonomy" } ] }, { "name": "vacuolar fusion protein MON1 homolog A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027270304", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270304" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270304", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270304" } ] }, { "annotation": "Plays an important role in membrane trafficking through the secretory apparatus.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW56", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW56#function" }, { "database": "UniProtKB", "id": "RU367048", "url": "https://www.uniprot.org/uniprotkb/RU367048#function" }, { "database": "UniProtKB", "id": "A0A8C2M558", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M558#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW56", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW56" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mon1a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW56", "locus": {} } ], "crossref": [ { "id": "A0A9J7FW56", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FW56", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756332", "url": "https://www.ncbi.nlm.nih.gov/gene/100756332", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756332", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756332", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FW56", "url": "https://www.orthodb.org/?gene=A0A9J7FW56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13027:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13027:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF19036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270304", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270304", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M558", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M558", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M558-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M558-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW56", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FW56-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIFPDGVSLRNSPGCPGACSVDQAGVELTEIYLPLPPVCWDQRRAPPPFRFHSIPFVRTVQKMAADMQRKRSSECPDGTLAPSDGQGVERAESPTPGLTQGTEPGAGQEGAMFVHARSYEDLTESEDREASGDSPKEYAGSPPPLPTDMRQISQDFSELSTQLTGVARDLQEEMLPGSSEDWLEPQGAAGRPATEPSQEGTTEGDEEDATEAWRLHQKHVFVLSEAGKPVYSRYGSEEALSSTMGVMVALVSFLEADKNAIRSIHADGYKVVFVRRSPLVLVAVARTRQSAQELAQELLYIYYQILSLLTGAQLSHIFQQKQNYDLRRLLSGSERITDNLLQLMARDPSFLMGAARCLPLAAAVRDTVSASLQQARARSLVFSILLARNQLVALVRRKDQFLHPIDLHLLFNLISSSSSFREGEAWTPVCLPKFNAAGFFHAHISYLEPDTDLCLLLVSTDREDFFAVSDCRRRFQERLRKRGAHLALREALRTPYYSVAQVGIPDLRHFLYKSKSSGLFTSPEIEAPYTSEEEQERLLGLYQYLHSRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWIRKEEDRLFILTPLTY", "length": 617, "header": "tr|A0A9J7FW56-1|A0A9J7FW56_CRIGR Isoform 1 of Vacuolar fusion protein MON1 homolog OS=Cricetulus griseus OX=10029 GN=Mon1a PE=3 SV=1 CANONICAL=A0A9J7FW56-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M558-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW56/entry#A0A8C2M558-1", "sequence": { "sequence": "MAADMQRKRSSECPDGTLAPSDGQGVERAESPTPGLTQGTEPGAGQEGAMFVHARSYEDLTESEDREASGDSPKEYAGSPPPLPTDMRQISQDFSELSTQLTGVARDLQEEMLPGSSEDWLEPQGAAGRPATEPSQEGTTEGDEEDATEAWRLHQKHVFVLSEAGKPVYSRYGSEEALSSTMGVMVALVSFLEADKNAIRSIHADGYKVVFVRRSPLVLVAVARTRQSAQELAQELLYIYYQILSLLTGAQLSHIFQQKQNYDLRRLLSGSERITDNLLQLMARDPSFLMGAARCLPLAAAVRDTVSASLQQARARSLVFSILLARNQLVALVRRKDQFLHPIDLHLLFNLISSSSSFREGEAWTPVCLPKFNAAGFFHAHISYLEPDTDLCLLLVSTDREDFFAVSDCRRRFQERLRKRGAHLALREALRTPYYSVAQVGIPDLRHFLYKSKSSGLFTSPEIEAPYTSEEEQERLLGLYQYLHSRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWIRKEEDRLFILTPLTY", "length": 555, "header": "tr|A0A8C2M558-1|A0A8C2M558_CRIGR Computationally mapped isoform of Vacuolar fusion protein MON1 homolog OS=Cricetulus griseus OX=10029 GN=Mon1a PE=3 SV=1 CANONICAL=A0A9J7FW56-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FW56-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW56/entry#A0A9J7FW56-1", "sequence": { "sequence": 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], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 95, "start_aa": "Thr", "end_pos": 95, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr95", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MIIKEYRIPLPLTVEEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENDDVFSLSPGEKNQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTHRGPLSDNWIEEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLNIENIRELEREVQLMLSRKMAQFAEEGGASELCKDITTQDQASGATSEPSSSNGESMGRGLKKQWSTSSKSSRSSKRGGQTITGGFCLPASPSRHSISEWRMQSIARDSDEDSDEEFFDAQEDLCNEEVFPKDITKWNSNDLMDKMENPEPEDPQDGIYHQSSPEFRVASSVEQLNIIEDEVSQPLAAPPSTIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFTLVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFSGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSSGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDPRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASILRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPHRDSFQETSVPVPALTWQDGPRQSLGCAESDVLQTHSTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAENYTASSIAQKGPSSLSHTPSVRRLSLLALPPPSPTTRGPRARARQVGPNLERFPCLPDLDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVTANHRINDAVANDDGPQIVTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVTYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVAFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVVVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMTGRLEPGAATGPK", "length": 1396, "header": "tr|A0A9J7FYG1-1|A0A9J7FYG1_CRIGR Isoform 1 of Membrane-associated phosphatidylinositol transfer protein 2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Pitpnm2 PE=3 SV=1 CANONICAL=A0A9J7FYG1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M2A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1/entry#A0A8C2M2A9-1", "sequence": { "sequence": "MIIKEYRIPLPLTVEEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENDDVFSLSPGEKNQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTHRGPLSDNWIEEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLNIENIRELEREVQLMLSRKMAQFAEEGGASELCKDITTQDQASGATSEPSSSNGESMGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDEDSDEEFFDAQEDLCNEEVFPKDITKWNSNDLMDKMENPEPEDPQDGIYHQSSPEFRVASSVEQLNIIEDEVSQPLAAPPSTIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFTLVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFSGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSSGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDPRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASILRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPHRDSFQETSVPVPALTWQDGPRQSLGCAESDVLQTHSTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAENYTASSIAQIAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVTANHRINDAVANDDGPQIVTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVTYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVAFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVVVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMTGRLEPGAATGPK", "length": 1331, "header": "tr|A0A8C2M2A9-1|A0A8C2M2A9_CRIGR Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 2 isoform X16 OS=Cricetulus griseus OX=10029 GN=Pitpnm2 PE=3 SV=1 CANONICAL=A0A9J7FYG1-1" }, "locus": {} }, { "isoform_ac": "A0A8C2M5F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1/entry#A0A8C2M5F5-1", "sequence": { "sequence": "MIIKEYRIPLPLTVEEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENDDVFSLSPGEKNQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTHRGPLSDNWIEEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLNIENIRELEREVQLMLSRKMAQFAEEGGASELCKDITTQDQASGATSEPSSSNGESMGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDEDSDEEFFDAQEDLCNEEVFPKDITKWNSNDLMDKMENPEPEDPQDGIYHQSSPEFRVASSVEQLNIIEDEVSQPLAAPPSTIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFTLVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFSGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSSGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDPRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASILRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLADVLQTHSTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAENYTASSIAQKGPSSLSHTPSVRRLSLLALPPPSPTTRGPRARARQVGPNLERFPCLPDLDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVTANHRINDAVANDDGPQIVTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVTYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVAFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVVVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMTGRLEPGAATGPK", "length": 1335, "header": "tr|A0A8C2M5F5-1|A0A8C2M5F5_CRIGR Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 2 isoform X15 OS=Cricetulus griseus OX=10029 GN=Pitpnm2 PE=3 SV=1 CANONICAL=A0A9J7FYG1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FW73-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1/entry#A0A9J7FW73-1", "sequence": { "sequence": "MIIKEYRIPLPLTVEEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENDDVFSLSPGEKNQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTHRGPLSDNWIEEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLNIENIRELEREVQLMLSRKMAQFAEEGGASELCKDITTQDQASGATSEPSSSNGESMGRGLKKQWSTSSKSSRSSKRGGQTITGGFCLPASPSRHSISEWRMQSIARDSDEDSDEEFFDAQEDLCNEEVFPKDITKWNSNDLMDKMENPEPEDPQDGIYHQSSPEFRVASSVEQLNIIEDEVSQPLAAPPSTIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFTLVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFSGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSSGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDPRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASILRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLADVLQTHSTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAENYTASSIAQKGPSSLSHTPSVRRLSLLALPPPSPTTRGPRARARQVGPNLERFPCLPDLDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVTANHRINDAVANDDGPQIVTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVTYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVAFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVVVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMTGRLEPGAATGPK", "length": 1346, "header": "tr|A0A9J7FW73-1|A0A9J7FYG1_CRIGR Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Pitpnm2 PE=3 SV=1 CANONICAL=A0A9J7FYG1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1/entry#A0A9J7FYG1-1", "sequence": { "sequence": "MIIKEYRIPLPLTVEEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENDDVFSLSPGEKNQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTHRGPLSDNWIEEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLNIENIRELEREVQLMLSRKMAQFAEEGGASELCKDITTQDQASGATSEPSSSNGESMGRGLKKQWSTSSKSSRSSKRGGQTITGGFCLPASPSRHSISEWRMQSIARDSDEDSDEEFFDAQEDLCNEEVFPKDITKWNSNDLMDKMENPEPEDPQDGIYHQSSPEFRVASSVEQLNIIEDEVSQPLAAPPSTIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFTLVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFSGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSSGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDPRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASILRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPHRDSFQETSVPVPALTWQDGPRQSLGCAESDVLQTHSTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAENYTASSIAQKGPSSLSHTPSVRRLSLLALPPPSPTTRGPRARARQVGPNLERFPCLPDLDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVTANHRINDAVANDDGPQIVTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVTYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVAFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVVVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMTGRLEPGAATGPK", "length": 1396, "header": "tr|A0A9J7FYG1-1|A0A9J7FYG1_CRIGR Isoform 1 of Membrane-associated phosphatidylinositol transfer protein 2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Pitpnm2 PE=3 SV=1 CANONICAL=A0A9J7FYG1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G0N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1/entry#A0A9J7G0N6-1", "sequence": { "sequence": "MIIKEYRIPLPLTVEEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENDDVFSLSPGEKNQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTHRGPLSDNWIEEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLNIENIRELEREVQLMLSRKMAQFAEEGGASELCKDITTQDQASGATSEPSSSNGESMGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDEDSDEEFFDAQEDLCNEEVFPKDITKWNSNDLMDKMENPEPEDPQDGIYHQSSPEFRVASSVEQLNIIEDEVSQPLAAPPSTIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFTLVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFSGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSSGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDPRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASILRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPHRDSFQETSVPVPALTWQDGPRQSLGCAESDVLQTHSTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAENYTASSIAQKGPSSLSHTPSVRRLSLLALPPPSPTTRGPRARARQVGPNLERFPCLPDLDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVTANHRINDAVANDDGPQIVTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVTYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVAFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVVVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMTGRLEPGAATGPK", "length": 1385, "header": "tr|A0A9J7G0N6-1|A0A9J7G0N6_CRIGR Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 2 isoform X12 OS=Cricetulus griseus OX=10029 GN=Pitpnm2 PE=3 SV=1 CANONICAL=A0A9J7FYG1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1/entry#A0A9J7GWM5-1", "sequence": { "sequence": "MIIKEYRIPLPLTVEEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENDDVFSLSPGEKNQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTHRGPLSDNWIEEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLNIENIRELEREVQLMLSRKMAQFAEEGGASELCKDITTQDQASGATSEPSSSNGESMGRGLKKQWSTSSKSSRSSKRGGQTITGGFCLPASPSRHSISEWRMQSIARDSDEDSDEEFFDAQEDLCNEEVFPKDITKWNSNDLMDKMENPEPEDPQDGIYHQSSPEFRVASSVEQLNIIEDEVSQPLAAPPSTIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFTLVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFSGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSSGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDPRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASILRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPHRDSFQETSVPVPALTWQDGPRQSLGCAESDVLQTHSTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAENYTASSIAQKGPSSLSHTPSVRRLSLLALPPPSPTTRGPRARARQVGPNLERFPCLPDLDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPREKWQRKRTHVKLRVRSSWCLGPTVFILFSPMQSEAMSHCCEPSYSINEE", "length": 1082, "header": "tr|A0A9J7GWM5-1|A0A9J7GWM5_CRIGR Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pitpnm2 PE=4 SV=1 CANONICAL=A0A9J7FYG1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1/entry#A0A9J7JLT1-1", "sequence": { "sequence": "MIIKEYRIPLPLTVEEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENDDVFSLSPGEKNQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTHRGPLSDNWIEEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLNIENIRELEREVQLMLSRKMAQFAEEGGASELCKDITTQDQASGATSEPSSSNGESMGRGLKKQWSTSSKSSRSSKRGGQTITGGFCLPASPSRHSISEWRMQSIARDSDEDSDEEFFDAQEDLCNEEVFPKDITKWNSNDLMDKMENPEPEDPQDGIYHQSSPEFRVASSVEQLNIIEDEVSQPLAAPPSTIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFTLVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFSGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSSGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDPRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASILRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPHRDSFQETSVPVPALTWQDGPRQSLGCAESDVLQTHSTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAENYTASSIAQIAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVTANHRINDAVANDDGPQIVTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVTYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVAFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVVVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMTGRLEPGAATGPK", "length": 1342, "header": "tr|A0A9J7JLT1-1|A0A9J7JLT1_CRIGR Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 2 isoform X14 OS=Cricetulus griseus OX=10029 GN=Pitpnm2 PE=3 SV=1 CANONICAL=A0A9J7FYG1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1/entry#A0A9J7JNP1-1", "sequence": { "sequence": "MIIKEYRIPLPLTVEEYRIAQLYMIQKKSRNETHGQGSGVEILENRPYTDGPGGSGQYTHKVYHVGMHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENDDVFSLSPGEKNQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTHRGPLSDNWIEEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLNIENIRELEREVQLMLSRKMAQFAEEGGASELCKDITTQDQASGATSEPSSSNGESMGRGLKKQWSTSSKSSRSSKRGASPSRHSISEWRMQSIARDSDEDSDEEFFDAQEDLCNEEVFPKDITKWNSNDLMDKMENPEPEDPQDGIYHQSSPEFRVASSVEQLNIIEDEVSQPLAAPPSTIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFTLVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFSGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSSGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDPRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASILRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLADVLQTHSTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAENYTASSIAQIAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVTANHRINDAVANDDGPQIVTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVTYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVAFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVVVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMTGRLEPGAATGPK", 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"length": 1289, "header": "tr|A0A9J7JPM3-1|A0A9J7JPM3_CRIGR Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 2 isoform X18 OS=Cricetulus griseus OX=10029 GN=Pitpnm2 PE=3 SV=1 CANONICAL=A0A9J7FYG1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K4E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1/entry#A0A9J7K4E5-1", "sequence": { "sequence": "MHIPGWFRSILPKAALRVVEESWNAYPYTRTRFTCPFVEKFSIDIETFYKTDTGENDDVFSLSPGEKNQLITDIIDIVKDPVPPSEYKTEEDPKLFQSVKTHRGPLSDNWIEEYKKRLLPIMCAYKLCKVEFRYWGMQSKIERFIHDTGLRRVMVRAHRQAWCWQDEWYGLNIENIRELEREVQLMLSRKMAQFAEEGGASELCKDITTQDQASGATSEPSSSNGESMGRGLKKQWSTSSKSSRSSKRGGQTITGGFCLPASPSRHSISEWRMQSIARDSDEDSDEEFFDAQEDLCNEEVFPKDITKWNSNDLMDKMENPEPEDPQDGIYHQSSPEFRVASSVEQLNIIEDEVSQPLAAPPSTIHVLLLVLHGGTILDTGAGDPSSKQGDTNTITNVFDTVMRVHYPSALGHLAIRLVPCPPICADAFTLVSNLSPYGHDEGCLSSSQDHIPLAALPLLATSSPQYQEAVATVIQRANLAYGDFIKSQEGVTFSGQVCLIGDCVGGILAFDALCYSGQPVSESQSSSRRGSVVSMQDADLLSPGILVNAAHCSSGSGGGSGGGSSLESSRHLSRSNIDIPRSNGTEDPRRQLPRKRSDSSTYELDTIQQHQAFLSSLHASILRNEPSSRRSSSSTMLDGAGALGKFDFEIADLFLFGCPLGLVLALRKTVIPSLDVFQLRPACQQVYNLFHPADPSASRLEPLLERRFHTLPPFSIPRYQRYPLGDGCSTLLVETVQRNPELVLEGGPLAPLPHRDSFQETSVPVPALTWQDGPRQSLGCAESDVLQTHSTVFQEHAAPSSPGTAPASRGFRRASEISIASQVSGMAENYTASSIAQKGPSSLSHTPSVRRLSLLALPPPSPTTRGPRARARQVGPNLERFPCLPDLDIGEVAAKWWGQKRIDYALYCPDALTAFPTVALPHLFHASYWESTDVVSFLLRQVMRHDSSSILELDGKEVSVFTPSQPREKWQRKRTHVKLRNVTANHRINDAVANDDGPQIVTGRFMYGPLDMVTLTGEKVDVHIMMQPPSGEWLYLDTLVTNSSGRVTYTIPETHRLGVGVYPIKMVVRGDHTFADSYITVLPKGTEFVVFSIDGSFAASVSIMGSDPKVRAGAVDVVRHWQDLGYLIIYVTGRPDMQKQRVVAWLAQHNFPHGVVAFCDGLVHDPLRHKANFLKLLISELHLRAHAAYGSTKDVVVYNSISLSPMHIYIVGRPTKKLQQQCQFITDGYAAHLAQLKYNHRARPARNTATRMALRKGSFGLPGQGDFLRSRNHLLRTISAQPSGPSHRHDRTQTQMDSEQRGQRSMSVAASCWGRAMTGRLEPGAATGPK", "length": 1330, "header": "tr|A0A9J7K4E5-1|A0A9J7K4E5_CRIGR Computationally mapped isoform of Membrane-associated phosphatidylinositol transfer protein 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Pitpnm2 PE=3 SV=1 CANONICAL=A0A9J7FYG1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW73", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW73" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW73", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW73" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771518", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771518", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1" } ], "pmid": "" }, { "name": "phosphatidylcholine binding", "id": "GO:0031210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031210", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1" } ], "pmid": "" }, { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG1" } ], "pmid": "" }, { "name": "phosphatidylinositol transfer activity", "id": "GO:0008526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008526", 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"glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1047, "end_pos": 1049 }, { "start_pos": 1108, "end_pos": 1110 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 649, "end_pos": 651 }, { "start_pos": 895, "end_pos": 897 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240653" }, "gene_names": [ { "name": "LOC100769335", "type": "recommended", "evidence": [ { "id": "A0A9J7FW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77" } ] }, { "name": "LOC100769335", "type": "synonym", "evidence": [ { "id": "XP_027240653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240653" } ] } ], "protein_names": [ { "name": "2'-5' oligoadenylate synthase", "type": "recommended", "evidence": [ { "id": "A0A9J7FW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77/entry#names_and_taxonomy" } ] }, { "name": "2'-5'-oligoadenylate synthase 1A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027240653", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240653" } ] }, { "name": "2.7.7.84", "type": "synonym", "evidence": [ { "id": "A0A9J7FW77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615718.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027240653", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240653" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100769335", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77", "locus": {} } ], "crossref": [ { "id": "A0A9J7FW77", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FW77", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05400", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05400", "database": "CDD", "categories": [ "Protein 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"categories": [ "Protein Classification" ] }, { "id": "cge:100769335", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769335", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FW77", "url": "https://www.orthodb.org/?gene=A0A9J7FW77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11258", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11258", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11258:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11258:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01909", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01909", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { 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"MEQGLSRTWACDLDKFIEAHLLPNTSFRTEVKAAIKIICDFLKERCFRDAAHPVRVSKVVKGGSSGKGTALKGRSDADLVVFLNNLTSFEDQLKRRGEFIQEIKKQLYELQHRSHIKVKFEVQSSKQSNLRALSFKLSSYQLQQEVEFDVLPAYDVLGQLNCSKPNPGIYSRLIRECTSLGKEGEFSTCFTELQRNFLKHRPPKLKSLIRLVKHWYQLCKEKLRELLPPQYALELLTVYAWERGSGVTEFNTAQGFRTVLELVTKYRQLRIYWTEYYDFQDQEVSNYLRRQLRKNRPVILDPADPTGNVAGLNSDGWKLLAEEALASLQYPCFKCCGGSPVRSWDVLPQVDEN", "length": 353, "header": "tr|A0A9J7FXH0-1|A0A9J7FXH0_CRIGR Computationally mapped isoform of 2'-5' oligoadenylate synthase OS=Cricetulus griseus OX=10029 GN=LOC100769335 PE=3 SV=1 CANONICAL=A0A9J7FW77-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769335", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769335", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW77", "url": 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77" } ], "pmid": "" }, { "name": "2'-5'-oligoadenylate synthetase activity", "id": "GO:0001730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FW77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FW77" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FW93-1", "uniprot_ac": "A0A9J7FW93", "uniprot_id": 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] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615107.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003511472.1. 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269555" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWA0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kl", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWA0", "locus": {} } ], "crossref": [ { "id": "A0A9J7FWA0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FWA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100758189", "url": "https://www.ncbi.nlm.nih.gov/gene/100758189", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758189", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758189", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FWA0", "url": "https://www.orthodb.org/?gene=A0A9J7FWA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10353:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10353:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FWA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MLTRLKANSEGKLAKQICRVVLDQFDKQYSKELGESWNTVRDVLISPSLWQYAILFNRFNYPLELEKDLHLRGYHPILQGSLPYYPKSMKCYLSRTPDRMPSERHQPGNLKRYYLLNAASLLPVLALELSDGETVLDLCAAPGGKSVALLQCAYPGYLLCNEYDSLRVRWLRQTLESFIPQSLTNAIKVSELDGREMGAAQPEVFDKVLVDAPCSNDRSWLFSSDSQKAACRIHQRNNLPVLQVELLRSAIKALRPGGLLVYSTCTLSKAENQDVISEILTSNSTIMPVDISAIARTCSQDFTFAPTGQQCSLLVIPEKGKAWGPMFVAKLKKSHEYRKMAMWILSQNRVSLPLELEL", "length": 358, "header": "tr|A0A9J7FWB3-1|A0A9J7FWI5_CRIGR Computationally mapped isoform of tRNA (Cytosine(34)-C(5))-methyltransferase, mitochondrial isoform X1 OS=Cricetulus griseus OX=10029 GN=Nsun3 PE=3 SV=1 CANONICAL=A0A9J7FWI5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWI5/entry#A0A9J7FWI5-1", "sequence": { "sequence": "MLTRLKANSEGKLAKQICRVVLDQFDKQYSKELGESWNTVRDVLISPSLWQYAILFNRFNYPLELEKDLHLRGYHPILQGSLPYYPKSMKCYLSRTPDRMPSERHQPGNLKRYYLLNAASLLPVLALELSDGETVLDLCAAPGGKSVALLQCAYPGYLLCNEYDSLRVRWLRQTLESFIPQSLTNAIKVSELDGREMGAAQPEVFDKVLVDAPCSNDRSWLFSSDSQKAACRIHQRNNLPVLQVELLRSAIKALRPGGLLVYSTCTLSKAENQDVISEILTSNSTIMPVDISAIARTCSQDFTFAPTGQQCSLLVIPEKGKAWGPMFVAKLKKSHEYRKMAMWIFLRSTRAEGSYGKIVDLIH", "length": 363, "header": "tr|A0A9J7FWI5-1|A0A9J7FWI5_CRIGR Isoform 1 of tRNA (Cytosine(34)-C(5))-methyltransferase, mitochondrial isoform X1 OS=Cricetulus griseus OX=10029 GN=Nsun3 PE=3 SV=1 CANONICAL=A0A9J7FWI5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWB3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWB3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWB3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWB3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769254", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769254", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWI5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA methylation", "id": "GO:0031167", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031167", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWI5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWI5" } ], "pmid": "" }, { "name": "RNA methyltransferase activity", "id": "GO:0008173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008173", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FWI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWI5" }, { "id": "PS51686", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51686" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM-dependent MTase RsmB/NOP-type", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 334, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 283, "end_pos": 285 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "A0A9J7FWC6-1", "uniprot_ac": "A0A9J7FWC6", "uniprot_id": "A0A9J7FWC6_CRIGR", "mass": { "chemical_mass": 116862.0, "monoisotopic_mass": 116862.0 }, "refseq": { "ac": "XP_003504294", "name": "microtubule-associated protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504294" }, "gene_names": [ { "name": "Map4", "type": "recommended", "evidence": [ { "id": "A0A9J7FWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6" } ] }, { "name": "Map4", "type": "synonym", "evidence": [ { "id": "XP_003504294", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504294" } ] } ], "protein_names": [ { "name": "Microtubule-associated protein", "type": "recommended", "evidence": [ { "id": "A0A9J7FWC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6/entry#names_and_taxonomy" } ] }, { "name": "microtubule-associated protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003504294", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504294" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614047.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504294", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504294" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Map4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6", "locus": {} } ], "crossref": [ { "id": "A0A9J7FWC6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FWC6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100763590", "url": "https://www.ncbi.nlm.nih.gov/gene/100763590", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027324", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027324", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763590", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763590", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FWC6", "url": "https://www.orthodb.org/?gene=A0A9J7FWC6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FZB3", "url": "https://www.orthodb.org/?gene=A0A9J7FZB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FZD2", "url": "https://www.orthodb.org/?gene=A0A9J7FZD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11501:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11501:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00418", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00418", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504294", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504294", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LVF8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZB3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQR1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADLSLVDALTDPPPEIEGEIKRDFIATLEAEPYDDTVGETVEKTEYIPLMDGDEKIGNPESKKKPCSDTSQADGIPSSKPTLLANGDHGMAANITTGSPTDFLEEKMAYQEYQNSQNWPEDASFCFQPQQVLGTNQADPLKVHHDDGLADLLFASSGPPNASAFIGQSDPLGDNYGMLPRDSLGPMAVVSPEWSVEASNSPHPESFISPEVVIETLQPAAELSKEIEVKSVKEQLPTKELEMMAEEKTTDVVPCRETDVSLSTDMTPGTETEVALAKDAEEATKPDVILSDALQPSIESDISLAEDMELCVGTEVTPVKDIILPTEADVSLTEGMAPPTEDEMVPDKDVTLPKETEMTLPIAMDLVPPEDMALVKETELAPVKGMVSLSEIEVSLAKDAESSTAEEMALPSDTPMVLTKDATLPLETEGSLVKGMTPSLETEMTLAKEIAPPIETKIDMVRDMASLPESEVSLGKEVVTLLEKQVVTEFNSSTPLSEKEVASVKDISLPPETEAPLGKDAVLPSETELTLDNNVTPAKDITLPSELEVAAVQIENKENEQAQEEFGEDSQLQSVQHKGQSAIPPCMILPEPVKAADQQFNLPIDEGSLENLEQKETSGSQPSELSSGIARQEEGKAAVSVTGNDITTPPNKELPPSPEKKGKPLATTQPAKTSTSKAKTQPTPLPKQPTPTTTGGLNKKPMSLASGSVPAAPPKRPAAATATTRPSTLPARDGKPKPITDAKIPEKRTSPSKPVSALRPGPKTIPTVSKATSPSTLVSTGPISRSPATPLPKRPISTKTEGKAADVKRMTAKSAPADLNRSKTTSASSVKRNTTPTGAAPPVGMTAPRVKPMSAPSRPSVALSVDKKPISAKPSSSAPRLSRLTPTASGPSLKSVRSKIGSTENIKHQPGGGRAKVEKKTEAAATAGKPEPNAVTKAAGSIGSAQRPPVGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGLPAGEELAIPEAEPDAGAPTSASGLSGHTTLSGGGDQREPQTLDSQIQETSI", "length": 1113, "header": "tr|A0A9J7FWC6-1|A0A9J7FWC6_CRIGR Isoform 1 of Microtubule-associated protein OS=Cricetulus griseus OX=10029 GN=Map4 PE=4 SV=1 CANONICAL=A0A9J7FWC6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LVF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6/entry#A0A8C2LVF8-1", "sequence": { "sequence": "MADLSLVDALTDPPPEIEGEIKRDFIATLEAEPYDDTVGETVEKTEYIPLMDGDEKIGNPESKKKPCSDTSQADGIPSSKPTLLANGDHGMAANITTGSPTDFLEEKMAYQEYQNSQNWPEDASFCFQPQQVLGTNQADPLKVHHDDGLADLLFASSGPPNASAFIGQSDPLGDNYGMLPRDSLGPMAVVSPEWSVEASNSPHPESFISPEVVIETLQPAAELSKEIEVKSVKEQLPTKELEMMAEEKTTDVVPCRETDVSLSTDMTPGTETEVALAKDAEEATKPDVILSDALQPSIESDISLAEDMELCVGTEVTPVKDIILPTEADVSLTEGMAPPTEDEMVPDKDVTLPKETEMTLPIAMDLVPPEDMALVKETELAPVKGMVSLSEIEVSLAKDAESSTAEEMALPSDTPMVLTKDATLPLETEGSLVKGMTPSLETEMTLAKEIAPPIETKIDMVRDMASLPESEVSLGKEVVTLLEKQVVTEFNSSTPLSEKEVASVKDISLPPETEAPLGKDAVLPSETELTLDNNVTPAKDITLPSELEVAAVQIENKENEQAQEEFGEDSQLQSVQHKGQSAIPPCMILPEPVKAADQQFNLPIDEGSLENLEQKETSGSQPSELSSGIARQEEGKAAVSVTGNDITTPPNKELPPSPEKKGKPLATTQPAKTSTSKAKTQPTPLPKQPTPTTTGGLNKKPMSLASGSVPAAPPKRPAAATATTRPSTLPARDGKPKPITDAKIPEKRTSPSKPVSALRPGPKTIPTVSKATSPSTLVSTGPISRSPATPLPKRPISTKTEGKAADVKRMTAKSAPADLNRSKTTSASSVKRNTTPTGAAPPVGMTAPRVKPMSAPSRPSVALSVDKKPISAKPSSSAPRLSRLTPTASGPSLKSVRSKIGSTENIKHQPGGGRAKVEKKTEAAATAGKPEPNAVTKAAGSIGSAQRPPVGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGLPAGEELAIPEAEPDAGAPTSASGLSGHTTLSGGGDQREPQTLDSQIQETN", "length": 1112, "header": "tr|A0A8C2LVF8-1|A0A8C2LVF8_CRIGR Computationally mapped isoform of Microtubule-associated protein OS=Cricetulus griseus OX=10029 GN=Map4 PE=4 SV=1 CANONICAL=A0A9J7FWC6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6/entry#A0A9J7FWC6-1", "sequence": { "sequence": "MADLSLVDALTDPPPEIEGEIKRDFIATLEAEPYDDTVGETVEKTEYIPLMDGDEKIGNPESKKKPCSDTSQADGIPSSKPTLLANGDHGMAANITTGSPTDFLEEKMAYQEYQNSQNWPEDASFCFQPQQVLGTNQADPLKVHHDDGLADLLFASSGPPNASAFIGQSDPLGDNYGMLPRDSLGPMAVVSPEWSVEASNSPHPESFISPEVVIETLQPAAELSKEIEVKSVKEQLPTKELEMMAEEKTTDVVPCRETDVSLSTDMTPGTETEVALAKDAEEATKPDVILSDALQPSIESDISLAEDMELCVGTEVTPVKDIILPTEADVSLTEGMAPPTEDEMVPDKDVTLPKETEMTLPIAMDLVPPEDMALVKETELAPVKGMVSLSEIEVSLAKDAESSTAEEMALPSDTPMVLTKDATLPLETEGSLVKGMTPSLETEMTLAKEIAPPIETKIDMVRDMASLPESEVSLGKEVVTLLEKQVVTEFNSSTPLSEKEVASVKDISLPPETEAPLGKDAVLPSETELTLDNNVTPAKDITLPSELEVAAVQIENKENEQAQEEFGEDSQLQSVQHKGQSAIPPCMILPEPVKAADQQFNLPIDEGSLENLEQKETSGSQPSELSSGIARQEEGKAAVSVTGNDITTPPNKELPPSPEKKGKPLATTQPAKTSTSKAKTQPTPLPKQPTPTTTGGLNKKPMSLASGSVPAAPPKRPAAATATTRPSTLPARDGKPKPITDAKIPEKRTSPSKPVSALRPGPKTIPTVSKATSPSTLVSTGPISRSPATPLPKRPISTKTEGKAADVKRMTAKSAPADLNRSKTTSASSVKRNTTPTGAAPPVGMTAPRVKPMSAPSRPSVALSVDKKPISAKPSSSAPRLSRLTPTASGPSLKSVRSKIGSTENIKHQPGGGRAKVEKKTEAAATAGKPEPNAVTKAAGSIGSAQRPPVGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGLPAGEELAIPEAEPDAGAPTSASGLSGHTTLSGGGDQREPQTLDSQIQETSI", "length": 1113, "header": "tr|A0A9J7FWC6-1|A0A9J7FWC6_CRIGR Isoform 1 of Microtubule-associated protein OS=Cricetulus griseus OX=10029 GN=Map4 PE=4 SV=1 CANONICAL=A0A9J7FWC6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6/entry#A0A9J7FXF5-1", "sequence": { "sequence": "MADLSLVDALTDPPPEIEGEIKRDFIATLEAEPYDDTVGETVEKTEYIPLMDGDEKIGNPESKKKPCSDTSQADGIPSSKPTLLANGDHGMAANITTGSPTDFLEEKMAYQEYQNSQNWPEDASFCFQPQQVLGTNQADPLKVHHDDGLADLLFASSGPPNASAFIGQSDPLGDNYDMTPGTETEVALAKDAEEATKPDVILSDALQPSIESDISLAEDMELCVGTEVTPVKDIILPTEADVSLTEGMAPPTEDEMVPDKDVTLPKETEMTLPIAMDLVPPEDMALVKETELAPVKGMVSLSEIEVSLAKDAESSTAEEMALPSDTPMVLTKDATLPLETEGSLVKGMTPSLETEMTLAKEIAPPIETKIDMVRDMASLPESEVSLGKEVVTLLEKQVVTEFNSSTPLSEKEVASVKDISLPPETEAPLGKDAVLPSETELTLDNNVTPAKDITLPSELEVAAVQIENKENEQAQEEFGEDSQLQSVQHKGQSAIPPCMILPEPVKAADQQFNLPIDEGSLENLEQKETSGSQPSELSSGIARQEEGKAAVSVTGNDITTPPNKELPPSPEKKGKPLATTQPAKTSTSKAKTQPTPLPKQPTPTTTGGLNKKPMSLASGSVPAAPPKRPAAATATTRPSTLPARDGKPKPITDAKIPEKRTSPSKPVSALRPGPKTIPTVSKATSPSTLVSTGPISRSPATPLPKRPISTKTEGKAADVKRMTAKSAPADLNRSKTTSASSVKRNTTPTGAAPPVGMTAPRVKPMSAPSRPSVALSVDKKPISAKPSSSAPRLSRLTPTASGPSLKSVRSKIGSTENIKHQPGGGRAKVEKKTEAAATAGKPEPNAVTKAAGSIGSAQRPPVGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGLPAGEELAIPEAEPDAGAPTSASGLSGHTTLSGGGDQREPQTLDSQIQETSI", "length": 1025, "header": "tr|A0A9J7FXF5-1|A0A9J7FXF5_CRIGR Computationally mapped isoform of Microtubule-associated protein OS=Cricetulus griseus OX=10029 GN=Map4 PE=4 SV=1 CANONICAL=A0A9J7FWC6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6/entry#A0A9J7FZB3-1", "sequence": { "sequence": "MADLSLVDALTDPPPEIEGEIKRDFIATLEAEPYDDTVGETVEKTEYIPLMDGDEKIGNPESKKKPCSDTSQADGIPSSKPTLLANGDHGMAANITTGSPTDFLEEKMAYQEYQNSQNWPEDASFCFQPQQVLGTNQADPLKVHHDDGLADLLFASSGPPNASAFIGQSDPLGDNYGMLPRDSLGPMAVVSPEWSVEASNSPHPESFISPEVVIETLQPAADMTPGTETEVALAKDAEEATKPDVILSDALQPSIESDISLAEDMELCVGTEVTPVKDIILPTEADVSLTEGMAPPTEDEMVPDKDVTLPKETEMTLPIAMDLVPPEDMALVKETELAPVKGMVSLSEIEVSLAKDAESSTAEEMALPSDTPMVLTKDATLPLETEGSLVKGMTPSLETEMTLAKEIAPPIETKIDMVRDMASLPESEVSLGKEVVTLLEKQVVTEFNSSTPLSEKEVASVKDISLPPETEAPLGKDAVLPSETELTLDNNVTPAKDITLPSELEVAAVQIENKENEQAQEEFGEDSQLQSVQHKGQSAIPPCMILPEPVKAADQQFNLPIDEGSLENLEQKETSGSQPSELSSGIARQEEGKAAVSVTGNDITTPPNKELPPSPEKKGKPLATTQPAKTSTSKAKTQPTPLPKQPTPTTTGGLNKKPMSLASGSVPAAPPKRPAAATATTRPSTLPARDGKPKPITDAKIPEKRTSPSKPVSALRPGPKTIPTVSKATSPSTLVSTGPISRSPATPLPKRPISTKTEGKAADVKRMTAKSAPADLNRSKTTSASSVKRNTTPTGAAPPVGMTAPRVKPMSAPSRPSVALSVDKKPISAKPSSSAPRLSRLTPTASGPSLKSVRSKIGSTENIKHQPGGGRAKVEKKTEAAATAGKPEPNAVTKAAGSIGSAQRPPVGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGLPAGEELAIPEAEPDAGAPTSASGLSGHTTLSGGGDQREPQTLDSQIQETSI", "length": 1070, "header": "tr|A0A9J7FZB3-1|A0A9J7FZB3_CRIGR Computationally mapped isoform of Microtubule-associated protein OS=Cricetulus griseus OX=10029 GN=Map4 PE=4 SV=1 CANONICAL=A0A9J7FWC6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6/entry#A0A9J7FZD2-1", "sequence": { "sequence": "MADLSLVDALTDPPPEIEGEIKRDFIATLEAEPYDDTVGETVEKTEYIPLMDGDEKIGNPESKKKPCSDTSQADGIPSSKPTLLANGDHGMAANITTGSPTDFLEEKMAYQEYQNSQNWPEDASFCFQPQQVLGTNQADPLKVHHDDGLADLLFASSGPPNASAFIGQSDPLGDNYELSKEIEVKSVKEQLPTKELEMMAEEKTTDVVPCRETDVSLSTDMTPGTETEVALAKDAEEATKPDVILSDALQPSIESDISLAEDMELCVGTEVTPVKDIILPTEADVSLTEGMAPPTEDEMVPDKDVTLPKETEMTLPIAMDLVPPEDMALVKETELAPVKGMVSLSEIEVSLAKDAESSTAEEMALPSDTPMVLTKDATLPLETEGSLVKGMTPSLETEMTLAKEIAPPIETKIDMVRDMASLPESEVSLGKEVVTLLEKQVVTEFNSSTPLSEKEVASVKDISLPPETEAPLGKDAVLPSETELTLDNNVTPAKDITLPSELEVAAVQIENKENEQAQEEFGEDSQLQSVQHKGQSAIPPCMILPEPVKAADQQFNLPIDEGSLENLEQKETSGSQPSELSSGIARQEEGKAAVSVTGNDITTPPNKELPPSPEKKGKPLATTQPAKTSTSKAKTQPTPLPKQPTPTTTGGLNKKPMSLASGSVPAAPPKRPAAATATTRPSTLPARDGKPKPITDAKIPEKRTSPSKPVSALRPGPKTIPTVSKATSPSTLVSTGPISRSPATPLPKRPISTKTEGKAADVKRMTAKSAPADLNRSKTTSASSVKRNTTPTGAAPPVGMTAPRVKPMSAPSRPSVALSVDKKPISAKPSSSAPRLSRLTPTASGPSLKSVRSKIGSTENIKHQPGGGRAKVEKKTEAAATAGKPEPNAVTKAAGSIGSAQRPPVGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGLPAGEELAIPEAEPDAGAPTSASGLSGHTTLSGGGDQREPQTLDSQIQETSI", "length": 1068, "header": "tr|A0A9J7FZD2-1|A0A9J7FZD2_CRIGR Computationally mapped isoform of Microtubule-associated protein OS=Cricetulus griseus OX=10029 GN=Map4 PE=4 SV=1 CANONICAL=A0A9J7FWC6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G0G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6/entry#A0A9J7G0G5-1", "sequence": { "sequence": "MADLSLVDALTDPPPEIEGEIKRDFIATLEAEPYDDTVGETVEKTEYIPLMDGDEKIGNPESKKKPCSDTSQADGIPSSKPTLLANGDHGMAANITTGSPTDFLEEKMAYQEYQNSQNWPEDASFCFQPQQVLGTNQAGMLPRDSLGPMAVVSPEWSVEASNSPHPESFISPEVVIETLQPAAELSKEIEVKSVKEQLPTKELEMMAEEKTTDVVPCRETDVSLSTDMTPGTETEVALAKDAEEATKPDVILSDALQPSIESDISLAEDMELCVGTEVTPVKDIILPTEADVSLTEGMAPPTEDEMVPDKDVTLPKETEMTLPIAMDLVPPEDMALVKETELAPVKGMVSLSEIEVSLAKDAESSTAEEMALPSDTPMVLTKDATLPLETEGSLVKGMTPSLETEMTLAKEIAPPIETKIDMVRDMASLPESEVSLGKEVVTLLEKQVVTEFNSSTPLSEKEVASVKDISLPPETEAPLGKDAVLPSETELTLDNNVTPAKDITLPSELEVAAVQIENKENEQAQEEFGEDSQLQSVQHKGQSAIPPCMILPEPVKAADQQFNLPIDEGSLENLEQKETSGSQPSELSSGIARQEEGKAAVSVTGNDITTPPNKELPPSPEKKGKPLATTQPAKTSTSKAKTQPTPLPKQPTPTTTGGLNKKPMSLASGSVPAAPPKRPAAATATTRPSTLPARDGKPKPITDAKIPEKRTSPSKPVSALRPGPKTIPTVSKATSPSTLVSTGPISRSPATPLPKRPISTKTEGKAADVKRMTAKSAPADLNRSKTTSASSVKRNTTPTGAAPPVGMTAPRVKPMSAPSRPSVALSVDKKPISAKPSSSAPRLSRLTPTASGPSLKSVRSKIGSTENIKHQPGGGRAKVEKKTEAAATAGKPEPNAVTKAAGSIGSAQRPPVGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGLPAGEELAIPEAEPDAGAPTSASGLSGHTTLSGGGDQREPQTLDSQIQETSI", "length": 1075, "header": "tr|A0A9J7G0G5-1|A0A9J7G0G5_CRIGR Computationally mapped isoform of Microtubule-associated protein OS=Cricetulus griseus OX=10029 GN=Map4 PE=4 SV=1 CANONICAL=A0A9J7FWC6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6/entry#A0A9J7JQR1-1", "sequence": { "sequence": "MADLSLVDALTDPPPEIEGEIKRDFIATLEAEPYDDTVGETVEKTEYIPLMDGDEKIGNPESKKKPCSDTSQADGIPSSKPTLLANGDHGMAANITTGSPTDFLEEKMAYQEYQNSQNWPEDASFCFQPQQVLGTNQADPLKVHHDDGLADLLFASSGPPNASAFIGQSDPLGDNYGMLPRDSLGPMAVVSPEWSVEASNSPHPESFISPEVVIETLQPAAELSKEIEVKSVKEQLPTKELEMMAEEKTTDVVPCRETDVSLSTDMTPGTETEVALAKDAEEATKPDVILSDALQPSIESDISLAEDMELCVGTEVTPVKDIILPTEADVSLTEGMAPPTEDEMVPDKDVTLPKETEMTLPIAMDLVPPEDMALVKETELAPVKGMVSLSEIEVSLAKDAESSTAEEMALPSDTPMVLTKDATLPLETEGSLVKGMTPSLETEMTLAKEIAPPIETKIDMVRDMASLPESEVSLGKEVVTLLEKQVVTEFNSSTPLSEKEVASVKDISLPPETEAPLGKDAVLPSETELTLDNNVTPAKDITLPSELEVAAVQIENKENEQAQEEFGEDSQLQSVQHKGQSAIPPCMILPEPVKAADQQFNLPIDEGSLENLEQKETSGSQPSELSSGIARQEEGKAAVSVTGNDITTPPNKELPPSPEKKGKPLATTQPAKTSTSKAKTQPTPLPKQPTPTTTGGLNKKPMSLASGSVPAAPPKRPAAATATTRPSTLPARDGKPKPITDAKIPEKRTSPSKPVSALRPGPKTIPTVSKATSPSTLVSTGPISRSPATPLPKRPISTKTEGKAADVKRMTAKSAPADLNRSKTTSASSVKRNTTPTGAAPPVGMTAPRVKPMSAPSRPSVALSVDKKPISAKPSSSAPRLSRLTPTASGPSLKSVRSKIGSTENIKHQPGGGRVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPPCPGLPAGEELAIPEAEPDAGAPTSASGLSGHTTLSGGGDQREPQTLDSQIQETSI", "length": 1075, "header": "tr|A0A9J7JQR1-1|A0A9J7JQR1_CRIGR Computationally mapped isoform of Microtubule-associated protein OS=Cricetulus griseus OX=10029 GN=Map4 PE=4 SV=1 CANONICAL=A0A9J7FWC6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763590", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763590", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 161, "end_pos": 163 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 820, "end_pos": 822 }, { "start_pos": 833, "end_pos": 835 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"MLSAMHMFLSPDFTGSVNITTPEQTIQEAQGETVHLPCMFTLSPEDQGPLDIEWLRLSGPNNEVVDRVIILYTVDKIYSDFYYDLKGRVNFTTNDIVSGDASIKIRNVRPSDSGTYQCKVKKAPGVAKTTIQLTVVDFTGSVNITTPEQTIQEAQGETVHLPCMFTLSPEDQGPLDIEWLRLSGPNNEVVDRVVIVYSADKISGDVYPDLKGRVHFTSHDIRSGDASINITNVQLSDAGTYQCRVKENPGIVNRNIKLTVTDFTGSVNITTPEQTIQEAQGETVHLPCMFTLSPEDQGPLFIDWMQLTGPENEVVNRMFIVNLADKIYDDFYQDMKGRVKFTSDNIRSGDASINISNVRLSDAGIYQCGMFHGSGEVKRTIQLTVVGKLLLLVESDGLLMG", "length": 401, "header": "tr|A0A9J7FWD5-1|A0A9J7FWD5_CRIGR Isoform 1 of Coxsackievirus and adenovirus receptor homolog isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100770536 PE=4 SV=1 CANONICAL=A0A9J7FWD5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FWD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWD5/entry#A0A9J7FWD5-1", "sequence": { "sequence": 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"length": 1224, "header": "tr|A0A9J7FWF3-1|A0A9J7FWF3_CRIGR Isoform 1 of Cilia- and flagella-associated protein 251 OS=Cricetulus griseus OX=10029 GN=Cfap251 PE=4 SV=1 CANONICAL=A0A9J7FWF3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 560, "start_aa": "Thr", "end_pos": 560, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr560", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly 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"https://www.uniprot.org/uniprotkb/A0A9J7FWF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" }, { "start_pos": 848, "end_pos": 850, "annotation": "n_glycosylation_sequon" }, { "start_pos": 997, "end_pos": 999, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 560 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 176, "end_pos": 178 }, { "start_pos": 758, "end_pos": 760 }, { "start_pos": 848, "end_pos": 850 }, { 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"length": 1172, "header": "tr|A0A9J7FWG4-1|A0A9J7FWG4_CRIGR Isoform 1 of Nuclear receptor-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Nrip1 PE=4 SV=1 CANONICAL=A0A9J7FWG4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765412", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765412", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG4" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG4" } ], "pmid": "" }, { "name": "cellular response to estradiol stimulus", "id": "GO:0071392", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071392", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWG4", "url": 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"id": "A0A9J7FWG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG4" } ], "pmid": "" }, { "name": "nuclear retinoid X receptor binding", "id": "GO:0046965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046965", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1009, "end_pos": 1011, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FWJ3-1", "uniprot_ac": "A0A9J7FWJ3", "uniprot_id": "A0A9J7FWJ3_CRIGR", "mass": { "chemical_mass": 34548.0, "monoisotopic_mass": 34548.0 }, "refseq": { "ac": "XP_027269131", "name": "olfactory receptor 5AC1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269131" }, "gene_names": [ { "name": "LOC100750595", "type": "recommended", "evidence": [ { "id": "A0A9J7FWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ3" } ] }, { "name": "LOC100750595", "type": "synonym", "evidence": [ { "id": "XP_027269131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269131" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7FWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ3/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5AC1-like", "type": 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5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 diphosphate.", "evidence": [ { "id": "2.7.7.84", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.84" }, { "id": "2.7.7.84", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.7.84" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FX41-1", "uniprot_ac": "A0A9J7FX41", "uniprot_id": "A0A9J7FX41_CRIGR", "mass": { "chemical_mass": 110695.0, "monoisotopic_mass": 110695.0 }, "refseq": { "ac": "XP_007639312", "name": "ubiquitin-like modifier-activating enzyme 7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639312" }, "gene_names": [ { "name": "Uba7", "type": "recommended", "evidence": [ { "id": "A0A9J7FX41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" } ] }, { "name": "Uba7", "type": "synonym", "evidence": [ { "id": "XP_007639312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639312" } ] } ], "protein_names": [ { "name": "Ubiquitin-like modifier-activating enzyme 7", "type": "recommended", "evidence": [ { "id": "A0A9J7FX41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41/entry#names_and_taxonomy" } ] }, { "name": "6.2.1.45", "type": "synonym", "evidence": [ { "id": "A0A9J7FX41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41/entry#names_and_taxonomy" } ] }, { "name": "Ubiquitin-activating enzyme E1 homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7FX41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-like modifier-activating enzyme 7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007639312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639312" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613788.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007639312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639312" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Uba7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41", "locus": {} } ], "crossref": [ { "id": "A0A9J7FX41", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FX41", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01491", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01491", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770619", "url": "https://www.ncbi.nlm.nih.gov/gene/100770619", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019572", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019572", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770619", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770619", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FWQ7", "url": "https://www.orthodb.org/?gene=A0A9J7FWQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FX41", "url": "https://www.orthodb.org/?gene=A0A9J7FX41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JHF7", "url": "https://www.orthodb.org/?gene=A0A9J7JHF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JQ31", "url": "https://www.orthodb.org/?gene=A0A9J7JQ31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10953", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10953", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10953:SF143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10953:SF143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00899", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00899", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09358", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09358", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16190", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16190", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007639312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FWQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX41-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVR8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVR8-1", "url": 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"MDEELYSRQLYVLGLPAMQRIQRARVLLSGLRGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQAPLAQLNEAVQISVHTGDITEDLLLAFQVVVLTNSKLEEQLKVGTFCHKHGIYFLVAETPGLVGRVFCDFGEDFTVADPTEVEPMTAAIQDISQGLPGIVTLRGDTKRHSFRDGDLVIFSGIEGMVELNNCSPQPVHVQKDGSLEIGDTSAFSRYLRGGVITEVKRPKTVRHKSLDTALLQPHVVVQSTQEAQRAHCLHQAFLALHKFQQLHGRLPKPWDPVDAETVVRVAQDLEPLTGTKEESLDEALLRKFALCSAGSLSPMAAILGGVAAQEVLKAISGKFMPLDQWLYFDALECLPEDEELLPNPEDCHPRNCRYDGQIAVFGTGFQQKLSYQHYLLQVGAGAIGCEMLKSFALMGLGVRANGGVAVADMDHIERSNLSRQFLFRPQDIGKPKAEVAATAAQRLNPDLQVTFYTNPLDPTTQHIFGDDFFSRVDGVVAALDSFEARHYVAARCTHYLKPLLEAGTQGTRGSASVFVPHVTEVYKGPISAADPEGVPHPLCTLRYFPSTVEHILQWARDEFEGLFSRSAETINCYQEACTSLSGMDRTQTLILLQQVMGVLKRRPKTWEDCVVWALGHWQLCFHDGIVELLRQFPPDKVLKDGTLFWSGSKSCPQPLQFDPNQDMHFLYVLAAANLYAQMHGLLGSHDQTALKELLQLLPEPASMHQSLISDGAFTAAEFGPEQLKELQELLRDWSKGPRLKPVLFEKNDDSNFHVDFVVAATDLRAQNYGILPVNHAQIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLSTFRRSYLHLAENYFIRSVPSAPALQLFQHLKWTCWDHLKVPAGQPERTLESLLAHLQEEQALKVEMLLYGPYILYSAQWPLEKQARCLCLRVTELVQQVTGREPEPGLRVLVLELSCEGEGDETAFPPLHYELW", "length": 997, "header": "tr|A0A9J7FX41-1|A0A9J7FX41_CRIGR Isoform 1 of Ubiquitin-like modifier-activating enzyme 7 OS=Cricetulus griseus OX=10029 GN=Uba7 PE=3 SV=1 CANONICAL=A0A9J7FX41-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FWQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41/entry#A0A9J7FWQ7-1", "sequence": { "sequence": "MDEELYSRQLYVLGLPAMQRIQRARVLLSGLRGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQAPLAQLNEAVQISVHTGDITEDLLLAFQVVVLTNSKLEEQLKVGTFCHKHGIYFLVAETPGLVGRVFCDFGEDFTVADPTEVEPMTAAIQDISQGLPGIVTLRGDTKRHSFRDGDLVIFSGIEGMVELNNCSPQPVHVQKDGSLEIGDTSAFSRYLRGGVITEVKRPKTVRHKSLDTALLQPHVVVQSTQEAQRAHCLHQAFLALHKFQQLHGRLPKPWDPVDAETVVRVAQDLEPLTGTKEESLDEALLRKFALCSAGSLSPMAAILGGVAAQEVLKAISGKFMPLDQWLYFDALECLPEDEELLPNPEDCHPRNCRYDGQIAVFGTGFQQKLSYQHYLLQVGAGAIGCEMLKSFALMGLGVRANGGVAVADMDHIERSNLSRQFLFRPQDIGKPKAEVAATAAQRLNPDLQVTFYTNPLDPTTQHIFGDDFFSRVDGVVAALDSFEARHYVAARCTHYLKPLLEAGTQGTRGSASVFVPHVTEVYKGPISAADPEGVPHPLCTLRYFPSTVEHILQWARDEFEGLFSRSAETINCYQEACTSLSGMDRTQTLILLQQVMGVLKRRPKTWEDCVVWALGHWQLCFHDGIVELLRQFPPDKVLKDGTLFWSGSKSCPQPLQFDPNQDMHFLYVLAAANLYAQMHGLLGSHDQTALKELLQLLPEPASMHQSLISDGAFTAAEFGPEQLKELQELLRDWSKGPRLKPVLFEKNDDSNFHVDFVVAATDLRAQNYGILPVNHAQIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLSTFRRSYLHLAENYFIRSVPSAPALQLFQHLKWTCWDHLKVPAGQPERTLESLLAHLQEEQALKVEMLLYGPYILYSAQWPLEKQARCLCLRPLTPS", "length": 959, "header": "tr|A0A9J7FWQ7-1|A0A9J7FX41_CRIGR Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme 7 OS=Cricetulus griseus OX=10029 GN=Uba7 PE=3 SV=1 CANONICAL=A0A9J7FX41-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FX41-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41/entry#A0A9J7FX41-1", "sequence": { "sequence": "MDEELYSRQLYVLGLPAMQRIQRARVLLSGLRGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQAPLAQLNEAVQISVHTGDITEDLLLAFQVVVLTNSKLEEQLKVGTFCHKHGIYFLVAETPGLVGRVFCDFGEDFTVADPTEVEPMTAAIQDISQGLPGIVTLRGDTKRHSFRDGDLVIFSGIEGMVELNNCSPQPVHVQKDGSLEIGDTSAFSRYLRGGVITEVKRPKTVRHKSLDTALLQPHVVVQSTQEAQRAHCLHQAFLALHKFQQLHGRLPKPWDPVDAETVVRVAQDLEPLTGTKEESLDEALLRKFALCSAGSLSPMAAILGGVAAQEVLKAISGKFMPLDQWLYFDALECLPEDEELLPNPEDCHPRNCRYDGQIAVFGTGFQQKLSYQHYLLQVGAGAIGCEMLKSFALMGLGVRANGGVAVADMDHIERSNLSRQFLFRPQDIGKPKAEVAATAAQRLNPDLQVTFYTNPLDPTTQHIFGDDFFSRVDGVVAALDSFEARHYVAARCTHYLKPLLEAGTQGTRGSASVFVPHVTEVYKGPISAADPEGVPHPLCTLRYFPSTVEHILQWARDEFEGLFSRSAETINCYQEACTSLSGMDRTQTLILLQQVMGVLKRRPKTWEDCVVWALGHWQLCFHDGIVELLRQFPPDKVLKDGTLFWSGSKSCPQPLQFDPNQDMHFLYVLAAANLYAQMHGLLGSHDQTALKELLQLLPEPASMHQSLISDGAFTAAEFGPEQLKELQELLRDWSKGPRLKPVLFEKNDDSNFHVDFVVAATDLRAQNYGILPVNHAQIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLSTFRRSYLHLAENYFIRSVPSAPALQLFQHLKWTCWDHLKVPAGQPERTLESLLAHLQEEQALKVEMLLYGPYILYSAQWPLEKQARCLCLRVTELVQQVTGREPEPGLRVLVLELSCEGEGDETAFPPLHYELW", "length": 997, "header": "tr|A0A9J7FX41-1|A0A9J7FX41_CRIGR Isoform 1 of Ubiquitin-like modifier-activating enzyme 7 OS=Cricetulus griseus OX=10029 GN=Uba7 PE=3 SV=1 CANONICAL=A0A9J7FX41-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41/entry#A0A9J7GVR8-1", "sequence": { "sequence": "MDEELYSRQLYVLGLPAMQRIQRARVLLSGLRGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQAPLAQLNEAVQISVHTGDITEDLLLAFQVVVLTNSKLEEQLKVGTFCHKHGIYFLVAETPGLVGRVFCDFGEDFTVADPTEVEPMTAAIQDISQGLPGIVTLRGDTKRHSFRDGDLVIFSGIEGMVELNNCSPQPVHVQKDGSLEIGDTSAFSRYLRGGVITEVKRPKTVRHKSLDTALLQPHVVVQSTQEAQRAHCLHQAFLALHKFQQLHGRLPKPWDPVDAETVVRVAQDLEPLTGTKEESLDEALLRKFALCSAGSLSPMAAILGGVAAQEVLKAISGKFMPLDQWLYFDALECLPEDEELLPNPEDCHPRNCRYDGQIAVFGTGFQQKLSYQHYLLQVGAGAIGCEMLKSFALMGLGVRANGGVAVADMDHIERSNLSRQFLFRPQDIGKPKAEVAATAAQRLNPDLQVTFYTNPLDPTTQHIFGDDFFSRVDGVVAALDSFEARHYVAARCTHYLKPLLEAGTQGTRGSASVFVPHVTEVYKGPISAADPEGVPHPLCTLRYFPSTVEHILQWARDEFEGLFSRSAETINCYQEACTSLSGMDRTQTLILLQQVMGVLKRRPKTWEDCVVWALGHWQLCFHDGIVELLRQFPPDKDGTLFWSGSKSCPQPLQFDPNQDMHFLYVLAAANLYAQMHGLLGSHDQTALKELLQLLPEPASMHQSLISDGAFTAAEFGPEQLKELQELLRDWSKGPRLKPVLFEKNDDSNFHVDFVVAATDLRAQNYGILPVNHAQIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLSTFRRSYLHLAENYFIRSVPSAPALQLFQHLKWTCWDHLKVPAGQPERTLESLLAHLQEEQALKVEMLLYGPYILYSAQWPLEKQARCLCLRVTELVQQVTGREPEPGLRVLVLELSCEGEGDETAFPPLHYELW", "length": 994, "header": "tr|A0A9J7GVR8-1|A0A9J7GVR8_CRIGR Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme 7 OS=Cricetulus griseus OX=10029 GN=Uba7 PE=3 SV=1 CANONICAL=A0A9J7FX41-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41/entry#A0A9J7JHF7-1", "sequence": { "sequence": "MDEELYSRQLYVLGLPAMQRIQRARVLLSGLRGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQAPLAQLNEAVQISVHTGDITEDLLLAFQVVVLTNSKLEEQLKVGTFCHKHGIYFLVAETPGLVGRVFCDFGEDFTVADPTEVEPMTAAIQDISQGLPGIVTLRGDTKRHSFRDGDLVIFSGIEGMVELNNCSPQPVHVQKDGSLEIGDTSAFSRYLRGGVITEVKRPKTVRHKSLDTALLQPHVVVQSTQEAQRAHCLHQAFLALHKFQQLHGRLPKPWDPVDAETVVRVAQDLEPLTGTKEESLDEALLRKFALCSAGSLSPMAAILGGVAAQEVLKAISGKFMPLDQWLYFDALECLPEDEELLPNPEDCHPRNCRYDGQIAVFGTGFQQKLSYQHYLLVGAGAIGCEMLKSFALMGLGVRANGGVAVADMDHIERSNLSRQFLFRPQDIGKPKAEVAATAAQRLNPDLQVTFYTNPLDPTTQHIFGDDFFSRVDGVVAALDSFEARHYVAARCTHYLKPLLEAGTQGTRGSASVFVPHVTEVYKGPISAADPEGVPHPLCTLRYFPSTVEHILQWARDEFEGLFSRSAETINCYQEACTSLSGMDRTQTLILLQQVMGVLKRRPKTWEDCVVWALGHWQLCFHDGIVELLRQFPPDKVLKDGTLFWSGSKSCPQPLQFDPNQDMHFLYVLAAANLYAQMHGLLGSHDQTALKELLQLLPEPASMHQSLISDGAFTAAEFGPEQLKELQELLRDWSKGPRLKPVLFEKNDDSNFHVDFVVAATDLRAQNYGILPVNHAQIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLSTFRRSYLHLAENYFIRSVPSAPALQLFQHLKWTCWDHLKVPAGQPERTLESLLAHLQEEQALKVEMLLYGPYILYSAQWPLEKQARCLCLRVTELVQQVTGREPEPGLRVLVLELSCEGEGDETAFPPLHYELW", "length": 996, "header": "tr|A0A9J7JHF7-1|A0A9J7JHF7_CRIGR Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme 7 OS=Cricetulus griseus OX=10029 GN=Uba7 PE=3 SV=1 CANONICAL=A0A9J7FX41-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JP19-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41/entry#A0A9J7JP19-1", "sequence": { "sequence": "MDEELYSRQLYVLGLPAMQRIQRARVLLSGLRGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQAPLAQLNEAVQISVHTGDITEDLLLAFQVVVLTNSKLEEQLKVGTFCHKHGIYFLVAETPGLVGRVFCDFGEDFTVADPTEVEPMTAAIQDISQGLPGIVTLRGDTKRHSFRDGDLVIFSGIEGMVELNNCSPQPVHVQKDGSLEIGDTSAFSRYLRGGVITEVKRPKTVRHKSLDTALLQPHVVVQSTQEAQRAHCLHQAFLALHKFQQLHGRLPKPWDPVDAETVVRVAQDLEPLTGTKEESLDEALLRKFALCSAGSLSPMAAILGGVAAQEVLKAISGKFMPLDQWLYFDALECLPEDEELLPNPEDCHPRNCRYDGQIAVFGTGFQQKLSYQHYLLQVGAGAIGCEMLKSFALMGLGVRANGGVAVADMDHIERSNLSRQFLFRPQDIGPKAEVAATAAQRLNPDLQVTFYTNPLDPTTQHIFGDDFFSRVDGVVAALDSFEARHYVAARCTHYLKPLLEAGTQGTRGSASVFVPHVTEVYKGPISAADPEGVPHPLCTLRYFPSTVEHILQWARDEFEGLFSRSAETINCYQEACTSLSGMDRTQTLILLQQVMGVLKRRPKTWEDCVVWALGHWQLCFHDGIVELLRQFPPDKVLKDGTLFWSGSKSCPQPLQFDPNQDMHFLYVLAAANLYAQMHGLLGSHDQTALKELLQLLPEPASMHQSLISDGAFTAAEFGPEQLKELQELLRDWSKGPRLKPVLFEKNDDSNFHVDFVVAATDLRAQNYGILPVNHAQIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLSTFRRSYLHLAENYFIRSVPSAPALQLFQHLKWTCWDHLKVPAGQPERTLESLLAHLQEEQALKVEMLLYGPYILYSAQWPLEKQARCLCLRVTELVQQVTGREPEPGLRVLVLELSCEGEGDETAFPPLHYELW", "length": 996, "header": "tr|A0A9J7JP19-1|A0A9J7JP19_CRIGR Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme 7 OS=Cricetulus griseus OX=10029 GN=Uba7 PE=3 SV=1 CANONICAL=A0A9J7FX41-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41/entry#A0A9J7JQ31-1", "sequence": { "sequence": "MDEELYSRQLYVLGLPAMQRIQRARVLLSGLRGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQAPLAQLNEAVQISVHTGDITEDLLLAFQVVVLTNSKLEEQLKVGTFCHKHGIYFLVAETPGLVGRVFCDFGEDFTVADPTEVEPMTAAIQDISQGLPGIVTLRGDTKRHSFRDGDLVIFSGIEGMVELNNCSPQPVHVQNGSLEIGDTSAFSRYLRGGVITEVKRPKTVRHKSLDTALLQPHVVVQSTQEAQRAHCLHQAFLALHKFQQLHGRLPKPWDPVDAETVVRVAQDLEPLTGTKEESLDEALLRKFALCSAGSLSPMAAILGGVAAQEVLKAISGKFMPLDQWLYFDALECLPEDEELLPNPEDCHPRNCRYDGQIAVFGTGFQQKLSYQHYLLQVGAGAIGCEMLKSFALMGLGVRANGGVAVADMDHIERSNLSRQFLFRPQDIGKPKAEVAATAAQRLNPDLQVTFYTNPLDPTTQHIFGDDFFSRVDGVVAALDSFEARHYVAARCTHYLKPLLEAGTQGTRGSASVFVPHVTEVYKGPISAADPEGVPHPLCTLRYFPSTVEHILQWARDEFEGLFSRSAETINCYQEACTSLSGMDRTQTLILLQQVMGVLKRRPKTWEDCVVWALGHWQLCFHDGIVELLRQFPPDKVLKDGTLFWSGSKSCPQPLQFDPNQDMHFLYVLAAANLYAQMHGLLGSHDQTALKELLQLLPEPASMHQSLISDGAFTAAEFGPEQLKELQELLRDWSKGPRLKPVLFEKNDDSNFHVDFVVAATDLRAQNYGILPVNHAQIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLSTFRRSYLHLAENYFIRSVPSAPALQLFQHLKWTCWDHLKVPAGQPERTLESLLAHLQEEQALKVEMLLYGPYILYSAQWPLEKQARCLCLRVTELVQQVTGREPEPGLRVLVLELSCEGEGDETAFPPLHYELW", "length": 996, "header": "tr|A0A9J7JQ31-1|A0A9J7JQ31_CRIGR Computationally mapped isoform of Ubiquitin-like modifier-activating enzyme 7 OS=Cricetulus griseus OX=10029 GN=Uba7 PE=3 SV=1 CANONICAL=A0A9J7FX41-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWQ7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWQ7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770619", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770619", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" } ], "pmid": "" }, { "name": "ubiquitin activating enzyme activity", "id": "GO:0004839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004839", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" } ], "pmid": "" }, { "name": "ISG15 activating enzyme activity", "id": "GO:0019782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019782", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" } ], "pmid": "" }, { "name": "ISG15-protein conjugation", "id": "GO:0032020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FX41", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX41" }, { "id": "SM00985", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00985" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-activating enzyme E1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 865, "end_pos": 992, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.2.1.45", "ec_name": "ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.", "evidence": [ { "id": "6.2.1.45", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.2.1.45" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 }, { "start_pos": 464, "end_pos": 466 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FWR0-1", "uniprot_ac": "A0A9J7FWR0", "uniprot_id": "A0A9J7FWR0_CRIGR", "mass": { "chemical_mass": 90866.0, "monoisotopic_mass": 90866.0 }, "refseq": { "ac": "XP_003498501", "name": "disintegrin and metalloproteinase domain-containing protein 1b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498501" }, "gene_names": [ { "name": "LOC100771654", "type": "recommended", "evidence": [ { "id": "A0A9J7FWR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWR0" } ] }, { "name": "LOC100771654", "type": "synonym", "evidence": [ { "id": "XP_003498501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498501" } ] } ], "protein_names": [ { "name": "Disintegrin and metalloproteinase domain-containing protein 1b", "type": "synonym", "evidence": [ { "id": "A0A9J7FWR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWR0/entry#names_and_taxonomy" } ] }, { "name": "disintegrin and metalloproteinase domain-containing protein 1b", "type": "synonym", "evidence": [ { "id": "XP_003498501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498501" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613692.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003498501.1. 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"MSVAASVKGITSILSSLQITKVALKEAKITSHIWAAQQLNLGLRLVPGHPSVKIGILVLLIFLPSTFCDIGPVYYSSYETVIPKRLPVEGSEDPGGRVSYMLLIQGQQQLLHLKVKGDYSVNNFPVYSYHNGILEQEMPLLSQDCHYEGYMEGVPGSFVSVNICSGLRGILIKEDTSYSIEPILSSKGFEHILYTVGLQPQASCSVTPKGSSGDTSQQQRNGKPDDPWELSDLRSHTKYVEMFVVVNHQRFQMWGSSVNETVGAVVDIIALTNSFTRGLNTEVVLVGMEIWTEGDPIEAPVDLQATLRDFNRWRQEKLVGRLRHDVAHLIVGHHPGENEGQAFLHGACSGGFAAAVEAFPHEDVLLFAALMAHELGHNLGIQHDHQACICDHKHFCLMHENITKGSGFSNCSSDDFYRFLHDHRGACLLDRPWHQSRKRRATRCGNGVVEDLEECDCGNGCADNQCCNDECKFKEGAECSNELCCSQCKFKNKGQICRPSVGICDLEEYCNGTSAICPEDRIVQDGSACHGSYICSEGHCLDPNSQCFRIFGYPAQSASDGCYHSLNSIGNQFGNCGVSSDSPGTYVKCSEQDALCGKLVCTDLGFLPPIKLKHILIQVPYTEEWCWSIGISDGRLDYPYEAYVMNNTPCGENKACNNFFCENMNEYSPDPSCGNQHCNAHGVCNDLGNCHCSHGFAPPDCMRKGNGGSVDSGPAGQQHEDVIEYESENSSINKNDLALNLKLIVLAAILILTILLIMICIVIAYSKSETPSEMAPQEEAEEEALSEETEGEEEEEEEEEVKEEEKEEEEEEKKEEAEAEKEGE", "length": 824, "header": "tr|A0A9J7FWR0-1|A0A9J7FWR0_CRIGR Isoform 1 of Disintegrin and metalloproteinase domain-containing protein 1b OS=Cricetulus griseus OX=10029 GN=LOC100771654 PE=4 SV=1 CANONICAL=A0A9J7FWR0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FWR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWR0/entry#A0A9J7FWR0-1", "sequence": { "sequence": 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analysis. 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"https://www.ncbi.nlm.nih.gov/protein/XP_027270048", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15229", "url": "https://www.rhea-db.org/rhea/15229", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FWS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTALFAEVLLFYKPVDRMTRSGVHLLALWAWATLHSAITKGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQMLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETEDPFFVLNSDVICDFPFQAMVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILSPSVLQRIQLKPTSIEKEVFPVMAQEGQLYAMELPGFWMDIGQPKDFLTGMCLFLQSLRQKHPERLCSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCVRRCTVLRDAHIRSHSWLESCIVGWRCRVGQWVRMENVTVLGEDVIVSDELYLNGASVLPHKSIGESVPEPRIIM", "length": 393, "header": "tr|A0A9J7FWS1-1|A0A9J7FWS1_CRIGR Isoform 1 of Mannose-1-phosphate guanylyltransferase catalytic subunit beta OS=Cricetulus griseus OX=10029 GN=Gmppb PE=3 SV=1 CANONICAL=A0A9J7FWS1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FWS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1/entry#A0A9J7FWS1-1", "sequence": { "sequence": "MGTALFAEVLLFYKPVDRMTRSGVHLLALWAWATLHSAITKGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQMLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETEDPFFVLNSDVICDFPFQAMVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILSPSVLQRIQLKPTSIEKEVFPVMAQEGQLYAMELPGFWMDIGQPKDFLTGMCLFLQSLRQKHPERLCSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCVRRCTVLRDAHIRSHSWLESCIVGWRCRVGQWVRMENVTVLGEDVIVSDELYLNGASVLPHKSIGESVPEPRIIM", "length": 393, "header": "tr|A0A9J7FWS1-1|A0A9J7FWS1_CRIGR Isoform 1 of Mannose-1-phosphate guanylyltransferase catalytic subunit beta OS=Cricetulus griseus OX=10029 GN=Gmppb PE=3 SV=1 CANONICAL=A0A9J7FWS1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760573", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760573", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mannose-1-phosphate guanylyltransferase (GTP) activity", "id": "GO:0004475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004475", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "GDP-mannose biosynthetic process", "id": "GO:0009298", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009298", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15229", "name": "", "equation": "alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7FWS1-1" ], "evidence": [ { "id": "15229", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15229" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7FWS1", "gene_name": "Gmppb", "activity": [ { "ec_number": "2.7.7.13", "activity": "alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate.", "evidence": [ { "id": "A0A9J7FWS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1" } ] }, { "ec_number": "2.7.7.13", "activity": "", "evidence": [ { "id": "A0A9J7FWS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FWS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1" }, { "id": "PF25087", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25087" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mannose-1-phosphate guanyltransferase C-terminal", "eco_id": "ECO_0000259", "start_pos": 283, "end_pos": 392, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FWS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS1" }, { "id": "PF00483", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00483" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nucleotidyl transferase", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 263, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.7.13", "ec_name": "alpha-D-mannose 1-phosphate + GTP + H(+) = GDP-alpha-D-mannose + diphosphate.", "evidence": [ { "id": "2.7.7.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.13" }, { "id": "2.7.7.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.7.13" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 355, "end_pos": 357 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FWT2-1", "uniprot_ac": "A0A9J7FWT2", "uniprot_id": "A0A9J7FWT2_CRIGR", "mass": { "chemical_mass": 132583.0, "monoisotopic_mass": 132583.0 }, "refseq": { "ac": "XP_027266982", "name": "protogenin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266982" }, "gene_names": [ { "name": "Prtg", "type": "recommended", "evidence": [ { "id": "A0A9J7FWT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2" } ] }, { "name": "Prtg", "type": "synonym", "evidence": [ { "id": "XP_027266982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266982" } ] } ], "protein_names": [ { "name": "Protogenin", "type": "recommended", "evidence": [ { "id": "A0A9J7FWT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2/entry#names_and_taxonomy" } ] }, { "name": "Protein Shen-Dan", "type": "synonym", "evidence": [ { "id": "A0A9J7FWT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2/entry#names_and_taxonomy" } ] }, { "name": "protogenin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027266982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266982" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266982" } ] }, { "annotation": "May play a role in anteroposterior axis elongation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2#function" }, { "database": "UniProtKB", "id": "ARBA00002140", "url": "https://www.uniprot.org/uniprotkb/ARBA00002140#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prtg", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2", "locus": {} } ], "crossref": [ { "id": "A0A9J7FWT2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FWT2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755217", "url": "https://www.ncbi.nlm.nih.gov/gene/100755217", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755217", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755217", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FWT2", "url": "https://www.orthodb.org/?gene=A0A9J7FWT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44170:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44170:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FWT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPVRPGMPPLLLLLLLLLLPSLGSLPGVWSFSELFFMKEPQDVTVTRKDSVSLDCQAHGEGPIKVTWMKNGAKLSENKRIQVLSNGSLYISEVEGRRGEQSDEGFYQCLAVNKYGAILSQKAHLTLSTISAFEVHPVSTEVHEGGVARFSCKISSNPPAVITWEFNRTSLPITMDRVTALPSGVLQIYDAGPEDAGNYRCVASTIAHKRKSMEASLTIIPANESRPFYMPTIVAGPQNVTVSLHQTAVLECMATGYPKPIISWSRLDHKSIDVFNTRVLGNGNLMISDVRLQHTGVYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGTARFVCQAEGTPSPKMSWLKNGRRIHSNGRIKMYNSKLVINQIIPEDDAFYQCMAENSQGSALSRARLTVVMSEDRPSAPYNVHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNEEYQVVLGNDTTHYIIDDLEPASSYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPPEISLTSRSPTDILVSWLPIPAKYRRGQVVLYRLSFRLSTENSIQVVELPGTVHEHLLEGLRPDSVYLVRITAGTRVGLGESSVWTSHRTPKATSVKAPKSPELHLEPLNCTTISVRWLQDTEDPATIQGYKLFYKEEGQQENGPIFLDTGDLLYTLSGLDPRRKYHVRLLAYNNMEDGYQADQTVSTPGCVSVRDRMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTTAQVINYTIRCNPVGLQNASLVLYLQTSETHMLVQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHSTLPEAPTGPPVGVKVTLIEDDTALVSWKPPDGPETVVTRYTILYASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVKISASNEVGEGPFSNSVELVVLPKDTSESNQRPKRLDSSDAKVYSGYYHLDQKSMTGIAVGVGIALTCILICVLILIYRSKARKSSASKTAQNGTQLLSRASASVASGSEMGKNLERATENEESLVPMVPSSFIDAKGGTDLIINSYGPIIKNNTKKKWLFFQDTKKMKTEQTPRRFTTQAVSFYQPGTTVLISDEDSPSSPGQTTSFPRPFGAALDSEHSANSEGSHETGDSGRFSHESNDEIHLSSVISSTPRISDSLTGGDPDGTATLEKHQDPAEPLPAEQTSSSPSSPSSPSSSSSTSAAQSAGLRFAADGFPI", "length": 1209, "header": "tr|A0A9J7FWT2-1|A0A9J7FWT2_CRIGR Isoform 1 of Protogenin OS=Cricetulus griseus OX=10029 GN=Prtg PE=3 SV=1 CANONICAL=A0A9J7FWT2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FWT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2/entry#A0A9J7FWT2-1", "sequence": { "sequence": 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"length": 1209, "header": "tr|A0A9J7FWT2-1|A0A9J7FWT2_CRIGR Isoform 1 of Protogenin OS=Cricetulus griseus OX=10029 GN=Prtg PE=3 SV=1 CANONICAL=A0A9J7FWT2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 817, "start_aa": "Thr", "end_pos": 817, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr817", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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[ { "database": "UniProtKB", "id": "A0A9J7FWT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2" } ], "pmid": "" }, { "name": "negative regulation of neurogenesis", "id": "GO:0050768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050768", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1043, "end_pos": 1045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, 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"A0A9J7FWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT7/entry#names_and_taxonomy" } ] }, { "name": "Tyrosine-protein kinase SgK269", "type": "synonym", "evidence": [ { "id": "A0A9J7FWT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT7/entry#names_and_taxonomy" } ] }, { "name": "inactive tyrosine-protein kinase PEAK1", "type": "synonym", "evidence": [ { "id": "XP_027270817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270817" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270817" } ] }, { "annotation": "Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics. 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"length": 1735, "header": "tr|A0A9J7FWT7-1|A0A9J7FWT7_CRIGR Isoform 1 of Inactive tyrosine-protein kinase PEAK1 OS=Cricetulus griseus OX=10029 GN=Peak1 PE=3 SV=1 CANONICAL=A0A9J7FWT7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1067, "start_aa": "Thr", "end_pos": 1067, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1067", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", 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"subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1533, "start_aa": "Thr", "end_pos": 1533, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1533", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758721", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758721", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT7" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWT7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1136, "end_pos": 1138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1544, 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"start_pos": 574, "end_pos": 576 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 674, "end_pos": 676 }, { "start_pos": 690, "end_pos": 692 }, { "start_pos": 890, "end_pos": 892 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FWU1-1", "uniprot_ac": "A0A9J7FWU1", "uniprot_id": "A0A9J7FWU1_CRIGR", "mass": { "chemical_mass": 32030.0, "monoisotopic_mass": 32030.0 }, "refseq": { "ac": "XP_027268488", "name": "complex I assembly factor TIMMDC1, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268488" }, "gene_names": [ { "name": "Timmdc1", "type": "recommended", "evidence": [ { "id": "A0A9J7FWU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU1" } ] }, { "name": "Timmdc1", "type": "synonym", "evidence": [ { "id": "XP_027268488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268488" } ] } ], "protein_names": [ { "name": "Complex I assembly factor TIMMDC1, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A9J7FWU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU1/entry#names_and_taxonomy" } ] }, { "name": "Translocase of inner mitochondrial membrane domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7FWU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU1/entry#names_and_taxonomy" } ] }, { "name": "complex I assembly factor TIMMDC1, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_027268488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268488" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268488" } ] }, { "annotation": "Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FWU5-1", "uniprot_ac": "A0A9J7FWU5", "uniprot_id": "A0A9J7FWU5_CRIGR", "mass": { "chemical_mass": 46419.0, "monoisotopic_mass": 46419.0 }, "refseq": { "ac": "XP_027267611", "name": "hepatocyte cell adhesion molecule isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267611" }, "gene_names": [ { "name": "LOC100753291", "type": "recommended", "evidence": [ { "id": "A0A9J7FWU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU5" } ] }, { "name": "LOC100753291", "type": "synonym", "evidence": [ { "id": "XP_027267611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267611" } ] } ], "protein_names": [ { "name": "Hepatic and glial cell adhesion molecule", "type": "recommended", "evidence": [ { "id": "A0A9J7FWU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU5/entry#names_and_taxonomy" } ] }, { "name": 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"MKREREALSRASRALRLAPFVYLLLIQPVPLEGVNITSPVRLIHGTVGKSALLSVQYSSTSSDKPVVKWQLKRDKPVTVVQSIGTEVIGTLRPDYRDRIRLFENGSLLLSDLQLADEGTYEVEISITDDTFTGEKTINLTVDVPISRPQVLVASTTVLELSEAFTLNCSHENGTKPSYTWLKDGKPLLNDSRMLLSPDQRVLTITRVLMEDDDLYSCVVENPISQVRSLPVKITVYRRSSLYIILSTGGIFLLVTLVTVCACWKPSKKSRKKRKLEKQNSLEYMDQNDDRLKSEADTLPRSGEQERKNPMALYILKDKDSPEPDENPATEPRSTTEPGPPGYSVSPPVPGRSPGLPIRSARRYPRSPALSPATGRTHTSPPRAPSSPSRSRNASHTLRTAGVHKIREQDEAGQVEISA", "length": 418, "header": "tr|A0A9J7FWU5-1|A0A9J7FWU5_CRIGR Isoform 1 of Hepatic and glial cell adhesion molecule OS=Cricetulus griseus OX=10029 GN=LOC100753291 PE=4 SV=1 CANONICAL=A0A9J7FWU5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FWU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU5/entry#A0A9J7FWU5-1", "sequence": { "sequence": 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753291", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753291", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU5" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FWU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWU5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 148, "end_pos": 234, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 138, "end_pos": 140 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 392, "end_pos": 394 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FWZ6-1", "uniprot_ac": "A0A9J7FWZ6", "uniprot_id": "A0A9J7FWZ6_CRIGR", "mass": { "chemical_mass": 98700.0, "monoisotopic_mass": 98700.0 }, "refseq": { "ac": "XP_027270953", "name": "rho GTPase-activating protein 42 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270953" }, "gene_names": [ { "name": "Arhgap42", "type": "recommended", "evidence": [ { "id": "A0A9J7FWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6" } ] }, { "name": "Arhgap42", "type": "synonym", "evidence": [ { "id": "XP_027270953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270953" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 42", "type": "recommended", "evidence": [ { "id": "A0A9J7FWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6/entry#names_and_taxonomy" } ] }, { "name": "Rho GTPase-activating protein 10-like", "type": "synonym", "evidence": [ { "id": "A0A9J7FWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 42", "type": "synonym", "evidence": [ { "id": "A0A9J7FWZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 42 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027270953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270953" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270953" } ] }, { "annotation": "May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6#function" }, { "database": "UniProtKB", "id": "ARBA00056973", "url": "https://www.uniprot.org/uniprotkb/ARBA00056973#function" }, { "database": "UniProtKB", "id": "A0A9J7GZE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZE8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FWZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arhgap42", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6", "locus": {} } ], "crossref": [ { "id": "A0A9J7FWZ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FWZ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01249", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01249", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07634", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07634", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757941", "url": "https://www.ncbi.nlm.nih.gov/gene/100757941", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757941", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757941", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FWZ6", "url": "https://www.orthodb.org/?gene=A0A9J7FWZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12552", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12552", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12552:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12552:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270953", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FWZ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELLKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILDKHLNLSAKKKESHLQEADSQIGREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKMFTMSVSEVKASGKMNGLLTGSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDIELWDNKTITSGLKNYLRCLAEPLMTYRLHKDFIIAVKSDDQDYRVEAVHALVHKLPEKNREMLDILIKHLLKVSLHSQQNLMTISNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPNIPLPQPQSRSSSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSTSCQPREKSGGIPWIASPSSSNGQKSLGLWTTSPESSSREDATKTDVESDCQSVASVTSPGDVSPPIDLVKKGPYGPSGLKRTSASSSLRSISAVEGNKSYSGSIQSLTSIGSKESPKATPNPELPPKMCRRLRLDTASSNGYQRPGSVVAAKAQIFENAGSLKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVHPSVEPGWLKATYEGRTGLVPENYVVFL", "length": 875, "header": "tr|A0A9J7FWZ6-1|A0A9J7FWZ6_CRIGR Isoform 1 of Rho GTPase-activating protein 42 OS=Cricetulus griseus OX=10029 GN=Arhgap42 PE=4 SV=1 CANONICAL=A0A9J7FWZ6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FWZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6/entry#A0A9J7FWZ6-1", "sequence": { "sequence": "MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELLKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILDKHLNLSAKKKESHLQEADSQIGREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKMFTMSVSEVKASGKMNGLLTGSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDIELWDNKTITSGLKNYLRCLAEPLMTYRLHKDFIIAVKSDDQDYRVEAVHALVHKLPEKNREMLDILIKHLLKVSLHSQQNLMTISNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPNIPLPQPQSRSSSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSTSCQPREKSGGIPWIASPSSSNGQKSLGLWTTSPESSSREDATKTDVESDCQSVASVTSPGDVSPPIDLVKKGPYGPSGLKRTSASSSLRSISAVEGNKSYSGSIQSLTSIGSKESPKATPNPELPPKMCRRLRLDTASSNGYQRPGSVVAAKAQIFENAGSLKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVHPSVEPGWLKATYEGRTGLVPENYVVFL", "length": 875, "header": "tr|A0A9J7FWZ6-1|A0A9J7FWZ6_CRIGR Isoform 1 of Rho GTPase-activating protein 42 OS=Cricetulus griseus OX=10029 GN=Arhgap42 PE=4 SV=1 CANONICAL=A0A9J7FWZ6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWZ6/entry#A0A9J7GZE8-1", "sequence": { "sequence": 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}, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FXK9-1", "uniprot_ac": "A0A9J7FXK9", "uniprot_id": "A0A9J7FXK9_CRIGR", "mass": { "chemical_mass": 71243.0, "monoisotopic_mass": 71243.0 }, "refseq": { "ac": "XP_007633420", "name": "protein mono-ADP-ribosyltransferase PARP6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007633420" }, "gene_names": [ { "name": "Parp6", "type": "recommended", "evidence": [ { "id": "A0A9J7FXK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9" } ] }, { "name": "Parp6", "type": "synonym", "evidence": [ { "id": "XP_007633420", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007633420" } ] } ], "protein_names": [ { "name": "Poly [ADP-ribose] polymerase", "type": "recommended", "evidence": [ { "id": "A0A9J7FXK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.-", "type": "synonym", "evidence": [ { "id": "A0A9J7FXK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9/entry#names_and_taxonomy" } ] }, { "name": "PARP", "type": "synonym", "evidence": [ { "id": "A0A9J7FXK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9/entry#names_and_taxonomy" } ] }, { "name": "protein mono-ADP-ribosyltransferase PARP6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007633420", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007633420" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613709.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007633420", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007633420" } ] }, { "annotation": "Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX83#function" }, { "database": "UniProtKB", "id": "ARBA00055359", "url": "https://www.uniprot.org/uniprotkb/ARBA00055359#function" }, { "database": "UniProtKB", "id": "A0A9J7FXK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9#function" }, { "database": "UniProtKB", "id": "A0A9J7FYB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYB7#function" }, { "database": "UniProtKB", "id": "A0A9J7JP98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP98#function" }, { "database": "UniProtKB", "id": "A0A8C2MHA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MHA6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Parp6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9", "locus": {} } ], "crossref": [ { "id": "cd01341", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01341", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750845", "url": "https://www.ncbi.nlm.nih.gov/gene/100750845", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750845", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750845", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MHA6", "url": "https://www.orthodb.org/?gene=A0A8C2MHA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FX83", "url": "https://www.orthodb.org/?gene=A0A9J7FX83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FXK9", "url": "https://www.orthodb.org/?gene=A0A9J7FXK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FYB7", "url": "https://www.orthodb.org/?gene=A0A9J7FYB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JP98", "url": "https://www.orthodb.org/?gene=A0A9J7JP98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007633420", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007633420", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "54424", "url": "https://www.rhea-db.org/rhea/54424", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "56612", "url": "https://www.rhea-db.org/rhea/56612", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MHA6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MHA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MHA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MHA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX83-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP98-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP98-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLRTEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPIPKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQIMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPSVVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSRQLKFMHTSHQFLLLSSPPAKEARFRTAKKLYGSTFAFHGSHIENWHSILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISFGYSGMGKGQHRMPSKDELVQRYNRMNTIPQTRSIQSRFLQSRNLNCIALCEVITSKDLQKHGNIWVCPVSDHVCTRFFFVYEDGQVGDANINTQDPKIQKEIMRVIGTQVYTN", "length": 631, "header": "tr|A0A9J7FXK9-1|A0A9J7FXK9_CRIGR Isoform 1 of Poly [ADP-ribose] polymerase OS=Cricetulus griseus OX=10029 GN=Parp6 PE=3 SV=1 CANONICAL=A0A9J7FXK9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MHA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9/entry#A0A8C2MHA6-1", "sequence": { "sequence": "MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLRTEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPIPKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQIMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPSVVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSRLKFMHTSHQFLLLSSPPAKEARFRTAKKLYGSTFAFHGSHIENWHSILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISFGYSGMGKGQHRMPSKDELVQRYNRMNTIPQTRSIQSRFLQSRNLNCIALCEVITSKDLQKHGNIWVCPVSDHVCTRFFFVYEDGQVGDANINTQDPKIQKEIMRVIGTQVYTN", "length": 630, "header": "tr|A0A8C2MHA6-1|A0A8C2MHA6_CRIGR Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Cricetulus griseus OX=10029 GN=Parp6 PE=3 SV=1 CANONICAL=A0A9J7FXK9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FX83-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9/entry#A0A9J7FX83-1", "sequence": { "sequence": "MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLRTEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPIPKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQVSGHCKNIPTLEYGFLVQIMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPSVVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSRLKFMHTSHQFLLLSSPPAKEARFRTAKKLYGSTFAFHGSHIENWHSILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISFGYSGMGKGQHRMPSKDELVQRYNRMNTIPQTRSIQSRFLQSRNLNCIALCEVITSKDLQKHGNIWVCPVSDHVCTRFFFVYEDGQVGDANINTQDPKIQKEIMRVIGTQVYTN", "length": 610, "header": "tr|A0A9J7FX83-1|A0A9J7FXK9_CRIGR Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Cricetulus griseus OX=10029 GN=Parp6 PE=3 SV=1 CANONICAL=A0A9J7FXK9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9/entry#A0A9J7FXK9-1", "sequence": { "sequence": "MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLRTEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPIPKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQIMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPSVVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSRQLKFMHTSHQFLLLSSPPAKEARFRTAKKLYGSTFAFHGSHIENWHSILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISFGYSGMGKGQHRMPSKDELVQRYNRMNTIPQTRSIQSRFLQSRNLNCIALCEVITSKDLQKHGNIWVCPVSDHVCTRFFFVYEDGQVGDANINTQDPKIQKEIMRVIGTQVYTN", "length": 631, "header": "tr|A0A9J7FXK9-1|A0A9J7FXK9_CRIGR Isoform 1 of Poly [ADP-ribose] polymerase OS=Cricetulus griseus OX=10029 GN=Parp6 PE=3 SV=1 CANONICAL=A0A9J7FXK9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9/entry#A0A9J7FYB7-1", "sequence": { "sequence": "MMMIQKETMNQRNFCMEFREYGTIDDVDIDLHINISFLDEEVSTAWKVLRTEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPIPKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQIMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPSVVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSRQLKFMHTSHQFLLLSSPPAKEARFRTAKKLYGSTFAFHGSHIENWHSILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISFGYSGMGKGQHRMPSKDELVQRYNRMNTIPQTRSIQSRFLQSRNLNCIALCEVITSKDLQKHGNIWVCPVSDHVCTRFFFVYEDGQVGDANINTQDPKIQKEIMRVIGTQVYTN", "length": 591, "header": "tr|A0A9J7FYB7-1|A0A9J7FYB7_CRIGR Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Cricetulus griseus OX=10029 GN=Parp6 PE=3 SV=1 CANONICAL=A0A9J7FXK9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JP98-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9/entry#A0A9J7JP98-1", "sequence": { "sequence": "MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLRTEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPIPKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQVSGHCKNIPTLEYGFLVQIMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPSVVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQWIISSNRSHIVKLPLSRQLKFMHTSHQFLLLSSPPAKEARFRTAKKLYGSTFAFHGSHIENWHSILRNGLVNASYTKLQLHGAAYGKGIYLSPISSISFGYSGMGKGQHRMPSKDELVQRYNRMNTIPQTRSIQSRFLQSRNLNCIALCEVITSKDLQKHGNIWVCPVSDHVCTRFFFVYEDGQVGDANINTQDPKIQKEIMRVIGTQVYTN", "length": 611, "header": "tr|A0A9J7JP98-1|A0A9J7JP98_CRIGR Computationally mapped isoform of Poly [ADP-ribose] polymerase OS=Cricetulus griseus OX=10029 GN=Parp6 PE=3 SV=1 CANONICAL=A0A9J7FXK9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 365, "start_aa": "Thr", "end_pos": 365, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr365", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX83" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX83" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750845", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750845", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXK9" } ], "pmid": "" }, { "name": "NAD+ poly-ADP-ribosyltransferase activity", "id": "GO:0003950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003950", "evidence": [ { "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7FX92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHP3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEREARRLLCTSSSRRCCPTPLLLLLLLPPLLLLLLGRPASGAAAVRSGSPPQSAGASVRTFTPFYFLEEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYAGNSAILNCEVNADLVTFVRWEQNRQPLLLDDRVVKLPSGTLVISNVTEGDGGLYRCIIESGGPPKYSDEAELKVLQGPEERLNLVFLIRPSSVTRVTGQSTVLPCVASGLPSPVIRWTKNEEVLDTESSERLVLLAGGSLEISDLTEDDAGTYFCIADNGNKTIEAQAELTVQAPPEFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERIENTSQPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITITWETPLTGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSATQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKALGSAGKGSRLPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDKSPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQPVISAHPIHSLDNPHHHFHSSSLASPARSHLYHPSSPWPIGTSMSLSDRANSTESVRNTPSTDTMPASSSQTCCTDHQDAEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPIYDPALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPPMPVVVPSAPEVQETTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA", "length": 1484, "header": "tr|A0A9J7FXL8-1|A0A9J7FXL8_CRIGR Isoform 1 of Neogenin OS=Cricetulus griseus OX=10029 GN=Neo1 PE=3 SV=1 CANONICAL=A0A9J7FXL8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FX92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL8/entry#A0A9J7FX92-1", "sequence": { "sequence": "MAAEREARRLLCTSSSRRCCPTPLLLLLLLPPLLLLLLGRPASGAAAVRSGSPPQSAGASVRTFTPFYFLEEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYAGNSAILNCEVNADLVTFVRWEQNRQPLLLDDRVVKLPSGTLVISNVTEGDGGLYRCIIESGGPPKYSDEAELKVLQGPEERLNLVFLIRPSSVTRVTGQSTVLPCVASGLPSPVIRWTKNEEVLDTESSERLVLLAGGSLEISDLTEDDAGTYFCIADNGNKTIEAQAELTVQAPPEFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERIENTSQPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITITWETPLTGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSATQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKALGSAGKGSRLPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDKSPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQQSVRNTPSTDTMPASSSQTCCTDHQDAEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPIYDPALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPPMPVVVPSAPEVQETTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA", "length": 1411, "header": "tr|A0A9J7FX92-1|A0A9J7FXL8_CRIGR Computationally mapped isoform of Neogenin OS=Cricetulus griseus OX=10029 GN=Neo1 PE=3 SV=1 CANONICAL=A0A9J7FXL8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL8/entry#A0A9J7FXL8-1", "sequence": { "sequence": "MAAEREARRLLCTSSSRRCCPTPLLLLLLLPPLLLLLLGRPASGAAAVRSGSPPQSAGASVRTFTPFYFLEEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYAGNSAILNCEVNADLVTFVRWEQNRQPLLLDDRVVKLPSGTLVISNVTEGDGGLYRCIIESGGPPKYSDEAELKVLQGPEERLNLVFLIRPSSVTRVTGQSTVLPCVASGLPSPVIRWTKNEEVLDTESSERLVLLAGGSLEISDLTEDDAGTYFCIADNGNKTIEAQAELTVQAPPEFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERIENTSQPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITITWETPLTGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSATQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKALGSAGKGSRLPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDKSPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQPVISAHPIHSLDNPHHHFHSSSLASPARSHLYHPSSPWPIGTSMSLSDRANSTESVRNTPSTDTMPASSSQTCCTDHQDAEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPIYDPALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPPMPVVVPSAPEVQETTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA", "length": 1484, "header": "tr|A0A9J7FXL8-1|A0A9J7FXL8_CRIGR Isoform 1 of Neogenin OS=Cricetulus griseus OX=10029 GN=Neo1 PE=3 SV=1 CANONICAL=A0A9J7FXL8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL8/entry#A0A9J7JHP3-1", "sequence": { "sequence": "MAAEREARRLLCTSSSRRCCPTPLLLLLLLPPLLLLLLGRPASGAAAVRSGSPPQSAGASVRTFTPFYFLEEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYAGNSAILNCEVNADLVTFVRWEQNRQPLLLDDRVVKLPSGTLVISNVTEGDGGLYRCIIESGGPPKYSDEAELKVLQGPEERLNLVFLIRPSSVTRVTGQSTVLPCVASGLPSPVIRWTKNEEVLDTESSERLVLLAGGSLEISDLTEDDAGTYFCIADNGNKTIEAQAELTVQAPPEFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERIENTSQPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITITWETPLTGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSATQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKALGSAGKGSRLPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDKSPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQPVISAHPIHSLDNPHHHFHSSSLASPARSHLYHPSSPWPIGTSMSLSDRANSTESVRNTPSTDTMPASSSQTCCTDHQDAEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPIYDPALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPPMPVVVPSAPEVQETTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA", "length": 1468, "header": "tr|A0A9J7JHP3-1|A0A9J7JHP3_CRIGR Computationally mapped isoform of Neogenin OS=Cricetulus griseus OX=10029 GN=Neo1 PE=3 SV=1 CANONICAL=A0A9J7FXL8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL8/entry#A0A9J7JPA3-1", "sequence": { "sequence": "MAAEREARRLLCTSSSRRCCPTPLLLLLLLPPLLLLLLGRPASGAAAVRSGSPPQSAGASVRTFTPFYFLEEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYAGNSAILNCEVNADLVTFVRWEQNRQPLLLDDRVVKLPSGTLVISNVTEGDGGLYRCIIESGGPPKYSDEAELKVLQGPEERLNLVFLIRPSSVTRVTGQSTVLPCVASGLPSPVIRWTKNEEVLDTESSERLVLLAGGSLEISDLTEDDAGTYFCIADNGNKTIEAQAELTVQAPPEFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHDVAIPTLPPTSLTSATTDHLAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERIENTSQPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITITWETPLTGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSATQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKALGSAGKGSRLPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDKSPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQQSVRNTPSTDTMPASSSQTCCTDHQDAEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPIYDPALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPPMPVVVPSAPEVQETTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA", "length": 1431, "header": "tr|A0A9J7JPA3-1|A0A9J7JPA3_CRIGR Computationally mapped isoform of Neogenin OS=Cricetulus griseus OX=10029 GN=Neo1 PE=3 SV=1 CANONICAL=A0A9J7FXL8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL8/entry#A0A9J7JQC0-1", "sequence": { "sequence": "MAAEREARRLLCTSSSRRCCPTPLLLLLLLPPLLLLLLGRPASGAAAVRSGSPPQSAGASVRTFTPFYFLEEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGFYQCVATVDNLGTIVSRTAKLTVAGLPRFTSQPEPSSVYAGNSAILNCEVNADLVTFVRWEQNRQPLLLDDRVVKLPSGTLVISNVTEGDGGLYRCIIESGGPPKYSDEAELKVLQGPEERLNLVFLIRPSSVTRVTGQSTVLPCVASGLPSPVIRWTKNEEVLDTESSERLVLLAGGSLEISDLTEDDAGTYFCIADNGNKTIEAQAELTVQAPPEFLKQPANIYAHESMDIVFECEVTGKPTPTVKWVKNGDVVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERIENTSQPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNIRAYATSPTSITITWETPLTGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTQDVAVRTLSDVPSAAPQNLSLEVRNSKSIVIHWQPPSSATQNGQITGYKIRYRKASRKSDVTETLVTGTQLSQLIEGLDRGTEYNFRVAALTVNGTGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGATFELVPTSPPKDVTVVSKEGKPRTIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPKALGSAGKGSRLPDLGSDYKPPMSGSNSPHGSPTSPLDSNMLLVIIVSVGVITIVVVVIIAVFCTRRTTSHQKKKRAACKSVNGSHKYKGNCKDVKPPDLWIHHERLELKPIDKSPDPNPVMTDTPIPRNSQDITPVDNSMDSNIHQRRNSYRGHESEDSMSTLAGRRGMRPKMMMPFDSQPPQPVISAHPIHSLDNPHHHFHSSSLASPARSHLYHPSSPWPIGTSMSLSDRANSTESVRNTPSTDTMPASSSQTCCTDHQDAEGATSSSYLASSQEEDSGQSLPTAHVRPSHPLKSFAVPAIPPPGPPIYDPALPSTPLLSQQALNHHIHSVKTASIGTLGRSRPPMPVVVPSAPEVQETTRMLEDSESSYEPDELTKEMAHLEGLMKDLNAITTA", "length": 1464, "header": "tr|A0A9J7JQC0-1|A0A9J7JQC0_CRIGR Computationally mapped isoform of Neogenin OS=Cricetulus griseus OX=10029 GN=Neo1 PE=3 SV=1 CANONICAL=A0A9J7FXL8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 886, "start_aa": "Thr", "end_pos": 886, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr886", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX92" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FX92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX92" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759045", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1169, "end_pos": 1171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1321, "end_pos": 1323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 749, "end_pos": 751, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" }, { "start_pos": 943, "end_pos": 945, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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"https://www.ncbi.nlm.nih.gov/protein/XP_027271380" }, "gene_names": [ { "name": "LOC100768006", "type": "recommended", "evidence": [ { "id": "A0A9J7FXJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXJ6" } ] }, { "name": "LOC100768006", "type": "synonym", "evidence": [ { "id": "XP_027271380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271380" } ] } ], "protein_names": [ { "name": "Interferon alpha/beta receptor 2", "type": "recommended", "evidence": [ { "id": "A0A9J7FXJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXJ6/entry#names_and_taxonomy" } ] }, { "name": "Type I interferon receptor 2", "type": "synonym", "evidence": [ { "id": "A0A9J7FXJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXJ6/entry#names_and_taxonomy" } ] }, { "name": "interferon alpha/beta receptor 2 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027271380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271380" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271380" } ] }, { "annotation": "Together with IFNAR1, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade, resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response. Mechanistically, type I interferon-binding brings the IFNAR1 and IFNAR2 subunits into close proximity with one another, driving their associated Janus kinases (JAKs) (TYK2 bound to IFNAR1 and JAK1 bound to IFNAR2) to cross-phosphorylate one another. The activated kinases phosphorylate specific tyrosine residues on the intracellular domains of IFNAR1 and IFNAR2, forming docking sites for the STAT transcription factors (STAT1, STAT2 and STAT). 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"MLPSHAFSIVRLLSLCLVVCVSLQFASSSVFEDYPKESCDVNLTLRNFRLILSWELKNKSIPLTHYTFWFTIMSKPEDPKALENCTNITEPSCDVTEEWTGPSEIYVPLIVIYRGNSTVSLCEGSVVATDTRVEPPEFEVVGFTDHINVTMKFPPVTPKIFGESIWEMLGYKSLVIREQAGQSIKLHKPTMKSITGNFTYVLRDLLPKTNYCVSVYFEAETLETSIKSPFKCTALQPDQESGSSEYDKVGIVTGCVIAVLFFSIVVMLKRIGYICLKHNFPNALNFHNFLSWIFPEVPPSEGVDKLEIIPSSKKKKVWNYDYGDGSDSDEDVPKASATGYTTHGLMGRLLSQASDPANHPLESQLEEDSAAEESDATGPGTEPELPTEAVVGLGLRPSEDPSGPYERRESVLQDSFPGDDSSSVNGTGDKVIFNVNLNSVFLRVLHDDSEGGSEVSSLAEDPVHLDEAPHRRESGLPMAGEDRTQSPHPSVSSQGLWTEDGSSEKTDTSDSDADTGDGYIMR", "length": 522, "header": "tr|A0A9J7G1L9-1|A0A9J7G1L9_CRIGR Computationally mapped isoform of Interferon alpha/beta receptor 2 OS=Cricetulus griseus OX=10029 GN=LOC100768006 PE=3 SV=1 CANONICAL=A0A9J7FXJ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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}, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { 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"https://www.ncbi.nlm.nih.gov/protein/XP_027270990" }, "gene_names": [ { "name": "Dcun1d5", "type": "recommended", "evidence": [ { "id": "A0A9J7FXM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0" } ] }, { "name": "Dcun1d5", "type": "synonym", "evidence": [ { "id": "XP_027270990", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270990" } ] } ], "protein_names": [ { "name": "DCN1-like protein", "type": "recommended", "evidence": [ { "id": "A0A9J7FXM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0/entry#names_and_taxonomy" } ] }, { "name": "DCN1-like protein 5 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027270990", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270990" } ] }, { "name": "Defective in cullin neddylation protein 1-like protein", "type": "synonym", "evidence": [ { "id": "A0A9J7FXM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270990" } ] }, { "annotation": "Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate in cell proliferation and anchorage-independent cell growth.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0#function" }, { "database": "UniProtKB", "id": "ARBA00046111", "url": "https://www.uniprot.org/uniprotkb/ARBA00046111#function" }, { "database": "UniProtKB", "id": "A0A9J7FYP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYP4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dcun1d5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0", "locus": {} } ], "crossref": [ { "id": "A0A9J7FXM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FXM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100759094", "url": "https://www.ncbi.nlm.nih.gov/gene/100759094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759094", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759094", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FXM0", "url": "https://www.orthodb.org/?gene=A0A9J7FXM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12281", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12281", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12281:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12281:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270990", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270990", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FXM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPVKKKRKAPGVAAEDAGLKKCKISSYCRSQPPARLISGEEDFSRKKCLAWFYEYAGPDEVVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQSRFDFLRSQLNDISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLLGRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGACFRGPVLLDEFVEWQKIRQTS", "length": 237, "header": "tr|A0A9J7FXM0-1|A0A9J7FXM0_CRIGR Isoform 1 of DCN1-like protein OS=Cricetulus griseus OX=10029 GN=Dcun1d5 PE=4 SV=1 CANONICAL=A0A9J7FXM0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FXM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0/entry#A0A9J7FXM0-1", "sequence": { "sequence": "MPVKKKRKAPGVAAEDAGLKKCKISSYCRSQPPARLISGEEDFSRKKCLAWFYEYAGPDEVVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQSRFDFLRSQLNDISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLLGRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGACFRGPVLLDEFVEWQKIRQTS", "length": 237, "header": "tr|A0A9J7FXM0-1|A0A9J7FXM0_CRIGR Isoform 1 of DCN1-like protein OS=Cricetulus griseus OX=10029 GN=Dcun1d5 PE=4 SV=1 CANONICAL=A0A9J7FXM0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0/entry#A0A9J7FYP4-1", "sequence": { "sequence": "MPVKKKRKAPGVAAEDAGLKKCKISSYCRSQPPARLISGEEDFSRKKCLAWFYEYAGPDEVVGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEWLKGMTSLQCDCTEKLQSRFDFLRSQLNDISSFKNIYRYAFDFARDKDQRSLDIDTAKSMLALLLGRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGAWPVLLDEFVEWQKIRQTS", "length": 234, "header": "tr|A0A9J7FYP4-1|A0A9J7FYP4_CRIGR Computationally mapped isoform of DCN1-like protein OS=Cricetulus griseus OX=10029 GN=Dcun1d5 PE=4 SV=1 CANONICAL=A0A9J7FXM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"id": "A0A9J7FXM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme binding", "id": "GO:0031624", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031624", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0" } ], "pmid": "" }, { "name": "ubiquitin ligase complex", "id": "GO:0000151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000151", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein neddylation", "id": "GO:0045116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045116", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FXM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM0" }, { "id": "PS51229", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51229" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DCUN1", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 232, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FXM3-1", "uniprot_ac": "A0A9J7FXM3", "uniprot_id": "A0A9J7FXM3_CRIGR", "mass": { "chemical_mass": 161090.0, "monoisotopic_mass": 161090.0 }, "refseq": { "ac": "XP_027270638", "name": "uveal autoantigen with coiled-coil domains and ankyrin repeats isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270638" }, "gene_names": [ { "name": "Uaca", "type": "recommended", "evidence": [ { "id": "A0A9J7FXM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3" } ] }, { "name": "Uaca", "type": "synonym", "evidence": [ { "id": "XP_027270638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270638" } ] } ], "protein_names": [ { "name": "Uveal autoantigen with coiled-coil domains and ankyrin repeats", "type": "recommended", "evidence": [ { "id": "A0A9J7FXM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3/entry#names_and_taxonomy" } ] }, { "name": "uveal autoantigen with coiled-coil domains and ankyrin repeats isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027270638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270638" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270638" } ] }, { "annotation": "Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3#function" }, { "database": "UniProtKB", "id": "ARBA00058204", "url": "https://www.uniprot.org/uniprotkb/ARBA00058204#function" }, { "database": "UniProtKB", "id": "A0A9J7G1U6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1U6#function" } ] }, { "annotation": "Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3#function" }, { "database": "UniProtKB", "id": "ARBA00057361", "url": "https://www.uniprot.org/uniprotkb/ARBA00057361#function" }, { "database": "UniProtKB", "id": "A0A9J7G1U6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1U6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Uaca", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3", "locus": {} } ], "crossref": [ { "id": "100753602", "url": "https://www.ncbi.nlm.nih.gov/gene/100753602", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753602", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753602", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FXM3", "url": "https://www.orthodb.org/?gene=A0A9J7FXM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24129:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24129:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270638", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FXM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1U6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1U6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSLKSRLWRQDAPVPTSPSSPTAVASTHLAEWNKYDDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVASKGNLECLNAILMHGIDVATSDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCRDAVEVLVKNGADVTLLDALGHDSSYYARIGDNLDILNLLKTASENTNKGRELWRKGLPLQQRNLSHTQDEGNMKSSQREHHSFQDLEIENEDLRERLRKIQQEQKILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESIRTIEALKSRFKYLESDHSVPGSYSSNRKEDMLHKQGQMYPTDSQCISPGVPTHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAATGSHRVTEELKEQLKDMKAKYEGASAEVGKLRNQIKQSEMLLEEFKRDEGRLVEENKRLQKECGTYEIEKEKKGRRVVELEGQLKELAAKLALSIPSEKFESMKSSLSNEVNEKVKRLAEVGRDYENSLGEIRQLKRELESARAKLTQHIRPEDHEQLKSRLEQKSGELGKRVTELTLKNQTLQKEVERVHVDNKRLSQQVHSLTVEMETCYVPLKANEEMKKSHDVSVEDLNKKLSEVTQKYTEKKLEAERLLVEKDRLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKKQLSELNKKCAEDQEKIHVLMSENTSLKKTLSSQYVPTKTHEEVKASLSSSLEKTNKALLDAKKRFDDISQECSKIRDENGVLRRNLENVQNQMKVDCVSLEEHSKKMNTVSQSLKEAQDANAAVLADYRRGQEEILTLHAEIKAQKKELDTIQECIKLKYAPLARLEESERKFKATEKGLREQLSEQTHKCRVRDEEVKKGKQENERLRQDLAALQKELKGKNAMVEEAREAERVLSGKTEELNKQLKDLSQKYTSVKNEKEKLAEEKAKQASEVLAAQNLLQKQPIPLEQVEALKTSLNDTIEHLREELRDKQRCLEKEQQSVSKLQQLLENQKNSSVPLADHLQIKEAFEKEVGIMKASLREKEEESQNKTKEVSKLQTEVQNTKQALKNLETREVIDMSKYKATKNDLETQISNLNDKLASLNRKYNQVCEEKFSAKDSKELLHLSIEQEIKDQKERCDKSLTTIMELQQRIQESAQQIEAKDNKITELLNDVERLKQALHGLSQLTYTSGSPTRRESQLVDTLQHRVRDLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", 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"MKSLKSRLWRQDAPVPTSPSSPTAVASTHLAEWNKYDDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVASKGNLECLNAILMHGIDVATSDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCRDAVEVLVKNGADVTLLDALGHDSSYYARIGDNLDILNLLKTASENTNKGRELWRKGLPLQQRNLSHTQDEGNMKSSQREHHSFQDLEIENEDLRERLRKIQQEQKILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESIRTIEALKSRFKYLESDHSVPGSYSSNRKEDMLHKQGQMYPTDSQCISPGVPTHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAATGSHRVTEELKEQLKDMKAKYEGASAEVGKLRNQIKQSEMLLEEFKRDEGRLVEENKRLQKECGTYEIEKEKKGRRVVELEGQLKELAAKLALSIPSEKFESMKSSLSNEVNEKVKRLAEVGRDYENSLGEIRQLKRELESARAKLTQHIRPEDHEQLKSRLEQKSGELGKRVTELTLKNQTLQKEVERVHVDNKRLSQQVHSLTVEMETCYVPLKANEEMKKSHDVSVEDLNKKLSEVTQKYTEKKLEAERLLVEKDRLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKKQLSELNKKCAEDQEKIHVLMSENTSLKKTLSSQYVPTKTHEEVKASLSSSLEKTNKALLDAKKRFDDISQECSKIRDENGVLRRNLENVQNQMKVDCVSLEEHSKKMNTVSQSLKEAQDANAAVLADYRRGQEEILTLHAEIKAQKKELDTIQECIKLKYAPLARLEESERKFKATEKGLREQLSEQTHKCRVRDEEVKKGKQENERLRQDLAALQKELKGKNAMVEEAREAERVLSGKTEELNKQLKDLSQKYTSVKNEKEKLAEEKAKQASEVLAAQNLLQKQPIPLEQVEALKTSLNDTIEHLREELRDKQRCLEKEQQSVSKLQQLLENQKNSSVPLADHLQIKEAFEKEVGIMKASLREKEEESQNKTKEVSKLQTEVQNTKQALKNLETREVIDMSKYKATKNDLETQISNLNDKLASLNRKYNQVCEEKFSAKDSKELLHLSIEQEIKDQKERCDKSLTTIMELQQRIQESAQQIEAKDNKITELLNDVERLKQALHGLSQLTYTSGSPTRRESQLVDTLQHRVRDLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1411, "header": "tr|A0A9J7FXM3-1|A0A9J7FXM3_CRIGR Isoform 1 of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Cricetulus griseus OX=10029 GN=Uaca PE=4 SV=1 CANONICAL=A0A9J7FXM3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3/entry#A0A9J7G1U6-1", "sequence": { "sequence": "MMNCWLSCAPKHTHLAEWNKYDDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVASKGNLECLNAILMHGIDVATSDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADINSRDKQNRTALMLGCEYGCRDAVEVLVKNGADVTLLDALGHDSSYYARIGDNLDILNLLKTASENTNKGRELWRKGLPLQQRNLSHTQDEGNMKSSQREHHSFQDLEIENEDLRERLRKIQQEQKILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESIRTIEALKSRFKYLESDHSVPGSYSSNRKEDMLHKQGQMYPTDSQCISPGVPTHMQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAATGSHRVTEELKEQLKDMKAKYEGASAEVGKLRNQIKQSEMLLEEFKRDEGRLVEENKRLQKECGTYEIEKEKKGRRVVELEGQLKELAAKLALSIPSEKFESMKSSLSNEVNEKVKRLAEVGRDYENSLGEIRQLKRELESARAKLTQHIRPEDHEQLKSRLEQKSGELGKRVTELTLKNQTLQKEVERVHVDNKRLSQQVHSLTVEMETCYVPLKANEEMKKSHDVSVEDLNKKLSEVTQKYTEKKLEAERLLVEKDRLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKKQLSELNKKCAEDQEKIHVLMSENTSLKKTLSSQYVPTKTHEEVKASLSSSLEKTNKALLDAKKRFDDISQECSKIRDENGVLRRNLENVQNQMKVDCVSLEEHSKKMNTVSQSLKEAQDANAAVLADYRRGQEEILTLHAEIKAQKKELDTIQECIKLKYAPLARLEESERKFKATEKGLREQLSEQTHKCRVRDEEVKKGKQENERLRQDLAALQKELKGKNAMVEEAREAERVLSGKTEELNKQLKDLSQKYTSVKNEKEKLAEEKAKQASEVLAAQNLLQKQPIPLEQVEALKTSLNDTIEHLREELRDKQRCLEKEQQSVSKLQQLLENQKNSSVPLADHLQIKEAFEKEVGIMKASLREKEEESQNKTKEVSKLQTEVQNTKQALKNLETREVIDMSKYKATKNDLETQISNLNDKLASLNRKYNQVCEEKFSAKDSKELLHLSIEQEIKDQKERCDKSLTTIMELQQRIQESAQQIEAKDNKITELLNDVERLKQALHGLSQLTYTSGSPTRRESQLVDTLQHRVRDLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGLVC", "length": 1396, "header": "tr|A0A9J7G1U6-1|A0A9J7G1U6_CRIGR Computationally mapped isoform of Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Cricetulus griseus OX=10029 GN=Uaca PE=4 SV=1 CANONICAL=A0A9J7FXM3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753602", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753602", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/A0A9J7FXM5" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FXM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXM5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 194, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 570 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 284, "end_pos": 286 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FXN8-1", "uniprot_ac": "A0A9J7FXN8", "uniprot_id": "A0A9J7FXN8_CRIGR", "mass": { "chemical_mass": 84327.0, "monoisotopic_mass": 84327.0 }, "refseq": { "ac": "XP_027271025", "name": "zinc finger protein with KRAB and SCAN domains 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271025" }, "gene_names": [ { "name": "Zkscan1", "type": "recommended", "evidence": [ { "id": "A0A9J7FXN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8" } ] }, { "name": "Zkscan1", "type": "synonym", "evidence": [ { "id": "XP_027271025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271025" } ] } ], "protein_names": [ { "name": "Zinc finger protein with KRAB and SCAN domains 1 isoform X4", "type": "synonym", "evidence": [ { "id": "A0A9J7FXN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein with KRAB and SCAN domains 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027271025", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271025" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271025" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7JMN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMN6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zkscan1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8", "locus": {} } ], "crossref": [ { "id": "A0A9J7FXN8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FXN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773451", "url": "https://www.ncbi.nlm.nih.gov/gene/100773451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003309", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003309", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "WEPLYIQ", "url": "https://omabrowser.org/oma/group/WEPLYIQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I1W7", "url": "https://www.orthodb.org/?gene=A0A061I1W7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FXN8", "url": "https://www.orthodb.org/?gene=A0A9J7FXN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JMN6", "url": "https://www.orthodb.org/?gene=A0A9J7JMN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271025", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271025", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I1W7", "url": "https://www.uniprot.org/uniprotkb/A0A061I1W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I1W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I1W7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSSVQETPPPDPEVFRQRFRRFCYQNTFGPREALNRLKELCHQWLRPEINSKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDHHEATHSHFKHASRKPRPLPSRALPVTHVPAPHHEGNPRDQAMASALLTADSQAMVKIEDMAVSLILEEWGCQNLARRNLNRDSRQENLGNVFSQGSENRNGKESTSKTDVKEDSTSHGETAGRVQKEFGEKREQQGRVVERTTLFLQRNHEEKTDKEKKEPGPPTTKEKKPTAGERGPREKGKGLGRSFSLSANFNNTSEELPSGAKTHRCDECGKCFTRSSSLIRHKIIHTGEKPYECNECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHTGEKRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNDCGKSFSQHAGLSSHQRLHTGEKPYKCEECGKAFNHSSNFNKHHRIHTGEKPYWCNHCGKTFCSKSNLSKHQRVHTGEGEAL", "length": 743, "header": "tr|A0A9J7FXN8-1|A0A9J7FXN8_CRIGR Isoform 1 of Zinc finger protein with KRAB and SCAN domains 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Zkscan1 PE=3 SV=1 CANONICAL=A0A9J7FXN8-1" }, "isoforms": [ { "isoform_ac": "A0A061I1W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8/entry#A0A061I1W7-1", "sequence": { "sequence": "MTKVVGMATVLGPRPPQEPLGPSTINAEEDEEKDSCRPSLEISRQRFRQFGYHDTPGPREALSQLRVLCCEWLQPEIHTKEQILELLVLEQFLTILPRELQAWVQQHCPENAEEAVTLLEDLEQELDEPGLQVSSPPNEQKQAWEKMSTSETTVESLSSTQAQSVDASPKYEFWGPLYIQETGEEEVFTQDPRKRQGLKSNPQKEDSADEQRSSEEESHADGLKRDIIPVIAANKYSRSRSQKQWANSLERGRGAKASLQDTGSRKGAEPVSAKAAPGEKRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNDCGKSFSQHAGLSSHQRLHTGEKPYKCEECGKAFNHSSNFNKHHRIHTGEKPYWCNHCGKTFCSKSNLSKHQRVHTGEGEAL", "length": 478, "header": "tr|A0A061I1W7-1|A0A061I1W7_CRIGR Computationally mapped isoform of Zinc finger protein with KRAB and SCAN domains 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Zkscan1 PE=3 SV=1 CANONICAL=A0A9J7FXN8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FXN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8/entry#A0A9J7FXN8-1", "sequence": { "sequence": "MTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSSVQETPPPDPEVFRQRFRRFCYQNTFGPREALNRLKELCHQWLRPEINSKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDHHEATHSHFKHASRKPRPLPSRALPVTHVPAPHHEGNPRDQAMASALLTADSQAMVKIEDMAVSLILEEWGCQNLARRNLNRDSRQENLGNVFSQGSENRNGKESTSKTDVKEDSTSHGETAGRVQKEFGEKREQQGRVVERTTLFLQRNHEEKTDKEKKEPGPPTTKEKKPTAGERGPREKGKGLGRSFSLSANFNNTSEELPSGAKTHRCDECGKCFTRSSSLIRHKIIHTGEKPYECNECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHTGEKRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNDCGKSFSQHAGLSSHQRLHTGEKPYKCEECGKAFNHSSNFNKHHRIHTGEKPYWCNHCGKTFCSKSNLSKHQRVHTGEGEAL", "length": 743, "header": "tr|A0A9J7FXN8-1|A0A9J7FXN8_CRIGR Isoform 1 of Zinc finger protein with KRAB and SCAN domains 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Zkscan1 PE=3 SV=1 CANONICAL=A0A9J7FXN8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JMN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8/entry#A0A9J7JMN6-1", "sequence": { "sequence": "MTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSSVQETPPPDPEVFRQRFRRFCYQNTFGPREALNRLKELCHQWLRPEINSKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEEAVTLLEDLELDLSGQQVPGQVHGPEMLARGMVPLDPVQESSSFDHHEATHSHFKHASRKPRPLPSRGSENRNGKESTSKTDVKEDSTSHGETAGRVQKEFGEKREQQGRVVERTTLFLQRNHEEKTDKEKKEPGPPTTKEKKPTAGERGPREKGKGLGRSFSLSANFNNTSEELPSGAKTHRCDECGKCFTRSSSLIRHKIIHTGEKPYECNECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHARERASEYSPASLDAFGAFLKSCV", "length": 492, "header": "tr|A0A9J7JMN6-1|A0A9J7JMN6_CRIGR Computationally mapped isoform of Zinc finger protein with KRAB and SCAN domains 1 OS=Cricetulus griseus OX=10029 GN=Zkscan1 PE=3 SV=1 CANONICAL=A0A9J7FXN8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXN8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q07231-1", "protein_name": "Zinc finger and SCAN domain-containing protein 21", "gene_name": "Zscan21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKVVGMATVLGPRPPQESMGPSPIKVEEDEEKDKCCPTLELSHKHFRQSGNQDTLEPMGPSTIKAEEDESKDKCRPNLEISRKSFKQFGYQDTLEQLGPSTIKAEEDDEKDKGHPSPEISRQRFRQFGYHDTPGPREALSQLRVLCCEWLQPEIHTKEQILELLVLEQFLTILPRELQTWVQQHCPESAEEAVTLLEDLEQELDEPGLQVSSPPNEQKQSWEKMSTSGTAMESLSSTETQHVDASPKYEFWGPLYIQETGEEEVFTQDPRKRQGFKSNPQKEDSADEHRSSEEESHADGLKRTVIPMIPANKYGSRSERQWANNLERERGTKASLQDTGSRKGAEPASTRPAPGEKRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCSHCGKTFCSKSNLSKHQRVHTGEGEVQ", "length": 555 }, "evidence": [ { "id": "A0A9J7FXN8", "url": "https://omabrowser.org/oma/group/A0A9J7FXN8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5A6-1", "protein_name": "Zinc finger and SCAN domain-containing protein 21", "gene_name": "ZSCAN21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269137" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXP5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100751765", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXP5", "locus": {} } ], "crossref": [ { "id": "A0A9J7FXP5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FXP5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751765", "url": "https://www.ncbi.nlm.nih.gov/gene/100751765", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751765", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FXP5", "url": "https://www.orthodb.org/?gene=A0A9J7FXP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269137", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269137", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FXP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGTENVTLLTQFVLTGLTHPPQWRIPLFLLFLVIYLITIVGNLGLIALIWNDSSLHIPMYLFLGSLAFVDTWLSSTVTPKMLLTFIAKSKLISLSECMIQFFSFVMCATMECFLLAAMAYDRYAAICKPLLYPVIMTNRLCVRLLVLTFVTGILHASIHEGMLFRLTFCNSNIIHHFYCDVMPLLKISCTDPSLNYLIVFIFSGSIQVFTISTILASYTLVLCTVLKKKSARGIKKAFSTCGAHLLSVSLYYGSLLFMYLLPASQKAQDEDMMDSVFYTVIIPVMNPIIYSLRNKQIKDSLEKFIKRNV", "length": 309, "header": "tr|A0A9J7FXP5-1|A0A9J7FXP5_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100751765 PE=3 SV=1 CANONICAL=A0A9J7FXP5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FXP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXP5/entry#A0A9J7FXP5-1", "sequence": { "sequence": "MGTENVTLLTQFVLTGLTHPPQWRIPLFLLFLVIYLITIVGNLGLIALIWNDSSLHIPMYLFLGSLAFVDTWLSSTVTPKMLLTFIAKSKLISLSECMIQFFSFVMCATMECFLLAAMAYDRYAAICKPLLYPVIMTNRLCVRLLVLTFVTGILHASIHEGMLFRLTFCNSNIIHHFYCDVMPLLKISCTDPSLNYLIVFIFSGSIQVFTISTILASYTLVLCTVLKKKSARGIKKAFSTCGAHLLSVSLYYGSLLFMYLLPASQKAQDEDMMDSVFYTVIIPVMNPIIYSLRNKQIKDSLEKFIKRNV", "length": 309, "header": "tr|A0A9J7FXP5-1|A0A9J7FXP5_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100751765 PE=3 SV=1 CANONICAL=A0A9J7FXP5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270195" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXR7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXR7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765707", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXR7", "locus": {} } ], "crossref": [ { "id": "cd05646", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05646", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765707", "url": "https://www.ncbi.nlm.nih.gov/gene/100765707", "database": "GeneID", "categories": [ 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXR7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXR7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765707", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765707", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "aminoacylase activity", "id": "GO:0004046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004046", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXR7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXR7" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXR7", 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FXW9-1", "uniprot_ac": "A0A9J7FXW9", "uniprot_id": "A0A9J7FXW9_CRIGR", "mass": { "chemical_mass": 156678.0, "monoisotopic_mass": 156678.0 }, "refseq": { "ac": "XP_027267750", "name": "B-cell CLL/lymphoma 9-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267750" }, "gene_names": [ { "name": "Bcl9l", "type": "recommended", "evidence": [ { "id": "A0A9J7FXW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" } ] }, { "name": "Bcl9l", "type": "synonym", "evidence": [ { "id": "XP_027267750", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267750" } ] } ], "protein_names": [ { "name": "B-cell CLL/lymphoma 9-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027267750", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267750" }, { "id": "A0A9J7FXW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267750" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bcl9l", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9", "locus": {} } ], "crossref": [ { "id": "100770128", "url": "https://www.ncbi.nlm.nih.gov/gene/100770128", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024670", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024670", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770128", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770128", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FXW9", "url": "https://www.orthodb.org/?gene=A0A9J7FXW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15185:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15185:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11502", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11502", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267750", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FXW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JFW0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JFW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVSQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRERSVSVDSGDQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGAAHNCNVGDPAMAAPQLGPGQTAQLPLSESSAPGPPHGPPPGLRPDVPGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILTYHQQNVPRAKLDQAPKVPPTPEPLPLNAPSAGTPQSQPPPLPPPPPAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAASANNPLPPGGDAGSAPGSTLLGEATAAGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAPAPSAAQQPPAAPPSGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPQGGDMGPQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGGMMGRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRAGPPFPGPRFPGNQMQRVPGFGSIQSMPMEVPMNAMQRPVRPGMGWTEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDPTMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVEPAMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSHKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPSQFPNQGQQGFSGGQGPYQAMPQDMGNTQDMFSPDQSSMPMGTVGTTRLSHMPLPPASNPPPGSVHPAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLSSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNINSSSNLGNMEQGTLPPSGPRNSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIALHPSAQGTGGPSQNSMMMAPGGPDSLSTPCGPGPSSSQMMPFPPRLQQPHGAMAPTAGGGGGPGLQQHYPSGMPLPPEDLPNQPPGPIPPQQHLMSKGMPGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYTQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPAPGGMANLPF", "length": 1497, "header": "tr|A0A9J7FXW9-1|A0A9J7FXW9_CRIGR Isoform 1 of B-cell CLL/lymphoma 9-like protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Bcl9l PE=3 SV=1 CANONICAL=A0A9J7FXW9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FXW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9/entry#A0A9J7FXW9-1", "sequence": { "sequence": "MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQNVSQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRERSVSVDSGDQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGAAHNCNVGDPAMAAPQLGPGQTAQLPLSESSAPGPPHGPPPGLRPDVPGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILTYHQQNVPRAKLDQAPKVPPTPEPLPLNAPSAGTPQSQPPPLPPPPPAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAASANNPLPPGGDAGSAPGSTLLGEATAAGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAPAPSAAQQPPAAPPSGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPQGGDMGPQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGGMMGRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRAGPPFPGPRFPGNQMQRVPGFGSIQSMPMEVPMNAMQRPVRPGMGWTEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDPTMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVEPAMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSHKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPSQFPNQGQQGFSGGQGPYQAMPQDMGNTQDMFSPDQSSMPMGTVGTTRLSHMPLPPASNPPPGSVHPAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLSSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNINSSSNLGNMEQGTLPPSGPRNSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIALHPSAQGTGGPSQNSMMMAPGGPDSLSTPCGPGPSSSQMMPFPPRLQQPHGAMAPTAGGGGGPGLQQHYPSGMPLPPEDLPNQPPGPIPPQQHLMSKGMPGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYTQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPAPGGMANLPF", "length": 1497, "header": "tr|A0A9J7FXW9-1|A0A9J7FXW9_CRIGR Isoform 1 of B-cell CLL/lymphoma 9-like protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Bcl9l PE=3 SV=1 CANONICAL=A0A9J7FXW9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JFW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9/entry#A0A9J7JFW0-1", "sequence": { "sequence": "MHPENKLTNHGKTGNGGAQSQHQNVSQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRERSVSVDSGDQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGAAHNCNVGDPAMAAPQLGPGQTAQLPLSESSAPGPPHGPPPGLRPDVPGGGGGGVPGKPPSQFVYVFTTHLANTAAEAVLQGRAESILTYHQQNVPRAKLDQAPKVPPTPEPLPLNAPSAGTPQSQPPPLPPPPPAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAASANNPLPPGGDAGSAPGSTLLGEATAAGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAPAPSAAQQPPAAPPSGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPQGGDMGPQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGLHGGRPLQDMVGMGGMMGRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRAGPPFPGPRFPGNQMQRVPGFGSIQSMPMEVPMNAMQRPVRPGMGWTEDLPPIGGPSNFAQNAVPYPGGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDPTMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVEPAMGPGNLNMNMNVNMNMNMNLNVQMTPQQQMLMSHKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPSQFPNQGQQGFSGGQGPYQAMPQDMGNTQDMFSPDQSSMPMGTVGTTRLSHMPLPPASNPPPGSVHPAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLSSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNINSSSNLGNMEQGTLPPSGPRNSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNNQPNQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIALHPSAQGTGGPSQNSMMMAPGGPDSLSTPCGPGPSSSQMMPFPPRLQQPHGAMAPTAGGGGGPGLQQHYPSGMPLPPEDLPNQPPGPIPPQQHLMSKGMPGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQQGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRGVGGEVYTQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPAPGGMANLPF", "length": 1460, "header": "tr|A0A9J7JFW0-1|A0A9J7JFW0_CRIGR Computationally mapped isoform of B-cell CLL/lymphoma 9-like protein isoform X2 OS=Cricetulus griseus OX=10029 GN=Bcl9l PE=3 SV=1 CANONICAL=A0A9J7FXW9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1076, "start_aa": "Thr", "end_pos": 1076, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1076", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1177, "start_aa": "Thr", "end_pos": 1177, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1177", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1315, "start_aa": "Thr", "end_pos": 1315, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1315", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 283, "start_aa": "Thr", "end_pos": 283, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr283", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770128", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770128", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "beta-catenin-TCF complex", "id": "GO:1990907", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990907", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1029, "end_pos": 1031, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1049, "end_pos": 1051, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" }, { "start_pos": 821, "end_pos": 823, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FXW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXW9" }, { "id": "PF11502", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11502" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B-cell lymphoma 9 beta-catenin binding", "eco_id": "ECO_0000259", "start_pos": 395, "end_pos": 429, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 283, 1076, 1177, 1315 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1029, "end_pos": 1031 }, { "start_pos": 1049, "end_pos": 1051 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 6, "end_pos": 8 }, { "start_pos": 821, "end_pos": 823 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FZH9-1", "uniprot_ac": "A0A9J7FZH9", "uniprot_id": "A0A9J7FZH9_CRIGR", "mass": { "chemical_mass": 268182.0, "monoisotopic_mass": 268182.0 }, "refseq": { "ac": "XP_027271717", "name": "tetratricopeptide repeat protein 28 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271717" }, "gene_names": [ { "name": "Ttc28", "type": "recommended", "evidence": [ { "id": "A0A9J7FZH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9" } ] }, { "name": "Ttc28", "type": "synonym", "evidence": [ { "id": "XP_027271717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271717" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 28", "type": "recommended", "evidence": [ { "id": "A0A9J7FZH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 28 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027271717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271717" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271717" } ] }, { "annotation": "During mitosis, may be involved in the condensation of spindle midzone microtubules, leading to the formation of midbody.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXY5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY5#function" }, { "database": "UniProtKB", "id": "ARBA00057010", "url": "https://www.uniprot.org/uniprotkb/ARBA00057010#function" }, { "database": "UniProtKB", "id": "A0A9J7FZH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ttc28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9", "locus": {} } ], "crossref": [ { "id": "100772639", "url": "https://www.ncbi.nlm.nih.gov/gene/100772639", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772639", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772639", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FXY5", "url": "https://www.orthodb.org/?gene=A0A9J7FXY5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FZH9", "url": "https://www.orthodb.org/?gene=A0A9J7FZH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10098", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10098", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10098:SF108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10098:SF108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26117", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26117", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271717", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FXY5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FXY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQPLTLAPEPSSARSRRRREPESPPAPIPLFGVKTIAQRSPDEPALSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKTQQYHKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDTLEPTYQQLQKMKLDKSPFVVVSVVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAHWSLGNTEKSTGYMQQDLDVAKTLGDHTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLRIAKDLGSKREEARAYSNLGSAYHYRRNFDKAMSYHNCVLELAQELMEKSIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLSIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFAKAEECQKYLLSLAQSLDNSQAKFRALGNLGDIFVCKKDVNGAIKFYEQQLGLAHHVKDRRLEASAYAALGTAYRMVQKYDKALGYHTQELEVYQELSDLTGECRAHGHLAAVYMALGKYTMAFKCYQEQLELGRKLKEPSLEAQVYGNMGITKMNMNVMEDAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRATGSLQQALVCFEKRLVVAHELGEASNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALHYHQLDLQIAEETDNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLVAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEALAVAERGRTRAFADLLVERQTGQQDSDPYSPITIDQILEMVNAQRGLVLYYSLAAGYLYSWLLAPGAGILKFHEHYLGDNSVEGSSDFQASSSASLPTATSSALEQHIASVREALGVESYYSRACASSETESEAGDIMEQQLEEMNKQLNSVTDPTGFLRMVRHNNLLHRSCQSMTSLFSGTMSPSKDGTSSLPRRQNSLAKPPLRALYDLLIAPMEGGLMHSSGPVGRHRQLVLVLEGELYLVPFALLKGSASNEYLYERFTLIAVPALRSLGPHSKCHLRKTPPTYSSSTAMAAVIGNPKLPSAVMDRWLWGPMPSAEEEAYMVSELLGCQPLVGSMATKERVMSALTQAECVHFATHISWKLSALVLTPNMEGNPASSKSSFGHPYTIPESLRVQDDASDGESISDCPPLRELLLTAADLLDLRLSVKLVILSSSQEANSRITADGLVALTRAFLAAGAQCVLVALWPVPVAASKMFIHAFYSSLLNGLKASASLGEAMKAVQSSKAFSHPSNWAGFTLIGSDVKLNSPSSLIGQALTEILQHPERARDALRVLLHLVEKSLQRIQNGQRNAMYTSQQSVENKVGGIPGWQALLTAVGFRLDPAASGLPAAVFFPTSDPGDRLQQCSSTLQALLGLPNPALQALCKLITASETGEQLISRAVKNMVGMLHQVLVQLQACEKEQDFASAPIPVSLSVQLWRLPGCHEFLAALGFDLCEVGQEEVILKTGKQASRRTTHFALQSLLSLFDSTELPKRLSLDSSSSLESLASAQSVSNALPLGYQHPPFSPTGADSIASDAISVYSLSSIASSMSFVSKPDGGLEGGGPRGRQDYDRPKSTHPQRATLPRRQLSPQARCGGSKEEEEYEGFSIISMEPLATYQGDGKARFSPDPKQPCVRAPGGVRLSVSSKGSVSTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQEEATPKLDPQELAQRILEETKSHLLAVERLQRSGGPAGKGPDREDGVVAAPNSTTVFRASETSAFSKPVLSHQRSQLSPLTIKPQPPARSSSLPKVSSPATSEVSSKDGLSSPSSSRPSPGRNTPASPADPPLFRLKYPSSPYSAHISKSPRNTSPGSGHQSPACSAPSPALSYSSAGSARSSPADAPDEKVQAVHSLKMLWQSAPQAPRGPQKICRGAPGALTSKRDVLSLLNLSPRHSKEEGGVDRLELKELPVQGRDEVPPKVPTNGHWCTETAALTTSGGLSTTAATRPLRLPLANGYKFLSPGRLFPSSKC", "length": 2460, "header": "tr|A0A9J7FZH9-1|A0A9J7FZH9_CRIGR Isoform 1 of Tetratricopeptide repeat protein 28 OS=Cricetulus griseus OX=10029 GN=Ttc28 PE=4 SV=1 CANONICAL=A0A9J7FZH9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FXY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9/entry#A0A9J7FXY5-1", "sequence": { "sequence": "MMKWQPRKKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDTLEPTYQQLQKMKLDKSPFVVVSVVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAHWSLGNTEKSTGYMQQDLDVAKTLGDHTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLRIAKDLGSKREEARAYSNLGSAYHYRRNFDKAMSYHNCVLELAQELMEKSIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLSIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFAKAEECQKYLLSLAQSLDNSQAKFRALGNLGDIFVCKKDVNGAIKFYEQQLGLAHHVKDRRLEASAYAALGTAYRMVQKYDKALGYHTQELEVYQELSDLTGECRAHGHLAAVYMALGKYTMAFKCYQEQLELGRKLKEPSLEAQVYGNMGITKMNMNVMEDAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRATGSLQQALVCFEKRLVVAHELGEASNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALHYHQLDLQIAEETDNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLVAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEALAVAERGRTRAFADLLVERQTGQQDSDPYSPITIDQILEMVNAQRGLVLYYSLAAGYLYSWLLAPGAGILKFHEHYLGDNSVEGSSDFQASSSASLPTATSSALEQHIASVREALGVESYYSRACASSETESEAGDIMEQQLEEMNKQLNSVTDPTGFLRMVRHNNLLHRSCQSMTSLFSGTMSPSKDGTSSLPRRQNSLAKPPLRALYDLLIAPMEGGLMHSSGPVGRHRQLVLVLEGELYLVPFALLKGSASNEYLYERFTLIAVPALRSLGPHSKCHLRKTPPTYSSSTAMAAVIGNPKLPSAVMDRWLWGPMPSAEEEAYMVSELLGCQPLVGSMATKERVMSALTQAECVHFATHISWKLSALVLTPNMEGNPASSKSSFGHPYTIPESLRVQDDASDGESISDCPPLRELLLTAADLLDLRLSVKLVILSSSQEANSRITADGLVALTRAFLAAGAQCVLVALWPVPVAASKMFIHAFYSSLLNGLKASASLGEAMKAVQSSKAFSHPSNWAGFTLIGSDVKLNSPSSLIGQALTEILQHPERARDALRVLLHLVEKSLQRIQNGQRNAMYTSQQSVENKVGGIPGWQALLTAVGFRLDPAASGLPAAVFFPTSDPGDRLQQCSSTLQALLGLPNPALQALCKLITASETGEQLISRAVKNMVGMLHQVLVQLQACEKEQDFASAPIPVSLSVQLWRLPGCHEFLAALGFDLCEVGQEEVILKTGKQASRRTTHFALQSLLSLFDSTELPKRLSLDSSSSLESLASAQSVSNALPLGYQHPPFSPTGADSIASDAISVYSLSSIASSMSFVSKPDGGLEGGGPRGRQDYDRPKSTHPQRATLPRRQLSPQARCGGSKEEEEYEGFSIISMEPLATYQGDGKARFSPDPKQPCVRAPGGVRLSVSSKGSVSTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQEEATPKLDPQELAQRILEETKSHLLAVERLQRSGGPAGKGPDREDGVVAAPNSTTVFRASETSAFSKPVLSHQRSQLSPLTIKPQPPARSSSLPKVSSPATSEVSSKDGLSSPSSSRPSPGRNTPASPADPPLFRLKYPSSPYSAHISKSPRNTSPGSGHQSPACSAPSPALSYSSAGSARSSPADAPDEKVQAVHSLKMLWQSAPQAPRGPQKICRGAPGALTSKRDVLSLLNLSPRHSKEEGGVDRLELKELPVQGRDEVPPKVPTNGHWCTETAALTTSGGLSTTAATRPLRLPLANGYKFLSPGRLFPSSKC", "length": 2348, "header": "tr|A0A9J7FXY5-1|A0A9J7FZH9_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 28 OS=Cricetulus griseus OX=10029 GN=Ttc28 PE=4 SV=1 CANONICAL=A0A9J7FZH9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9/entry#A0A9J7FZH9-1", "sequence": { "sequence": "MEQPLTLAPEPSSARSRRRREPESPPAPIPLFGVKTIAQRSPDEPALSKAEFVEKVRQSNQACHDGDFHTAIVLYNEALAVDPQNCILYSNRSAAYMKTQQYHKALDDAIKARLLNPKWPKAYFRQGVALQYLGRHADALAAFASGLAQDPKSLQLLVGMVEAAMKSPMRDTLEPTYQQLQKMKLDKSPFVVVSVVGQELLTAGHHGASVVVLEAALKIGTCSLKLRGSVFSALSSAHWSLGNTEKSTGYMQQDLDVAKTLGDHTGECRAHGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTAIGDYPNALASHKQCVLLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLRIAKDLGSKREEARAYSNLGSAYHYRRNFDKAMSYHNCVLELAQELMEKSIEMRAYAGLGHAARCMQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGIIHQMKGDYDTALKLHKTHLSIAQELSDYAAQGRAYGNMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHYQNHLNIARELRDIQSEARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFAKAEECQKYLLSLAQSLDNSQAKFRALGNLGDIFVCKKDVNGAIKFYEQQLGLAHHVKDRRLEASAYAALGTAYRMVQKYDKALGYHTQELEVYQELSDLTGECRAHGHLAAVYMALGKYTMAFKCYQEQLELGRKLKEPSLEAQVYGNMGITKMNMNVMEDAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRATGSLQQALVCFEKRLVVAHELGEASNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALHYHQLDLQIAEETDNPTCQGRAYGNLGLTYESLGTFERAVVYQEQHLSIAAQMNDLVAKTVSYSSLGRTHHALQNYSQAVMYLQEGLRLAEQLGRREDEAKIRHGLGLSLWASGNLEEAQHQLYRASALFETIRHEAQLSTDYKLSLFDLQTSSYQALQRVLVSLGHHDEALAVAERGRTRAFADLLVERQTGQQDSDPYSPITIDQILEMVNAQRGLVLYYSLAAGYLYSWLLAPGAGILKFHEHYLGDNSVEGSSDFQASSSASLPTATSSALEQHIASVREALGVESYYSRACASSETESEAGDIMEQQLEEMNKQLNSVTDPTGFLRMVRHNNLLHRSCQSMTSLFSGTMSPSKDGTSSLPRRQNSLAKPPLRALYDLLIAPMEGGLMHSSGPVGRHRQLVLVLEGELYLVPFALLKGSASNEYLYERFTLIAVPALRSLGPHSKCHLRKTPPTYSSSTAMAAVIGNPKLPSAVMDRWLWGPMPSAEEEAYMVSELLGCQPLVGSMATKERVMSALTQAECVHFATHISWKLSALVLTPNMEGNPASSKSSFGHPYTIPESLRVQDDASDGESISDCPPLRELLLTAADLLDLRLSVKLVILSSSQEANSRITADGLVALTRAFLAAGAQCVLVALWPVPVAASKMFIHAFYSSLLNGLKASASLGEAMKAVQSSKAFSHPSNWAGFTLIGSDVKLNSPSSLIGQALTEILQHPERARDALRVLLHLVEKSLQRIQNGQRNAMYTSQQSVENKVGGIPGWQALLTAVGFRLDPAASGLPAAVFFPTSDPGDRLQQCSSTLQALLGLPNPALQALCKLITASETGEQLISRAVKNMVGMLHQVLVQLQACEKEQDFASAPIPVSLSVQLWRLPGCHEFLAALGFDLCEVGQEEVILKTGKQASRRTTHFALQSLLSLFDSTELPKRLSLDSSSSLESLASAQSVSNALPLGYQHPPFSPTGADSIASDAISVYSLSSIASSMSFVSKPDGGLEGGGPRGRQDYDRPKSTHPQRATLPRRQLSPQARCGGSKEEEEYEGFSIISMEPLATYQGDGKARFSPDPKQPCVRAPGGVRLSVSSKGSVSTPNSPVKMTLIPSPNSPFQKVGKLASSDTGESDQSSTETDSTVKSQEEATPKLDPQELAQRILEETKSHLLAVERLQRSGGPAGKGPDREDGVVAAPNSTTVFRASETSAFSKPVLSHQRSQLSPLTIKPQPPARSSSLPKVSSPATSEVSSKDGLSSPSSSRPSPGRNTPASPADPPLFRLKYPSSPYSAHISKSPRNTSPGSGHQSPACSAPSPALSYSSAGSARSSPADAPDEKVQAVHSLKMLWQSAPQAPRGPQKICRGAPGALTSKRDVLSLLNLSPRHSKEEGGVDRLELKELPVQGRDEVPPKVPTNGHWCTETAALTTSGGLSTTAATRPLRLPLANGYKFLSPGRLFPSSKC", "length": 2460, "header": "tr|A0A9J7FZH9-1|A0A9J7FZH9_CRIGR Isoform 1 of Tetratricopeptide repeat protein 28 OS=Cricetulus griseus OX=10029 GN=Ttc28 PE=4 SV=1 CANONICAL=A0A9J7FZH9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXY5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FXY5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXY5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772639", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772639", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1086, "end_pos": 1088, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2196, "end_pos": 2198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2297, "end_pos": 2299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2378, "end_pos": 2380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 864, "end_pos": 866, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FZH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9" }, { "id": "PF12770", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12770" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CHAT", "eco_id": "ECO_0000259", "start_pos": 1385, "end_pos": 1707, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FZH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH9" }, { "id": "PF26117", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26117" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TTC28 C-terminal", "eco_id": "ECO_0000259", "start_pos": 1821, "end_pos": 1936, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1086, "end_pos": 1088 }, { "start_pos": 2196, "end_pos": 2198 }, { "start_pos": 2297, "end_pos": 2299 }, { "start_pos": 2378, "end_pos": 2380 }, { "start_pos": 864, "end_pos": 866 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FY04-1", "uniprot_ac": "A0A9J7FY04", "uniprot_id": "A0A9J7FY04_CRIGR", "mass": { "chemical_mass": 49079.0, "monoisotopic_mass": 49079.0 }, "refseq": { "ac": "XP_027270910", "name": "sperm equatorial segment protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270910" }, "gene_names": [ { "name": "Spesp1", "type": "recommended", "evidence": [ { "id": "A0A9J7FY04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04" } ] }, { "name": "Spesp1", "type": "synonym", "evidence": [ { "id": "XP_027270910", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270910" } ] } ], "protein_names": [ { "name": "Sperm equatorial segment protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7FY04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04/entry#names_and_taxonomy" } ] }, { "name": "sperm equatorial segment protein 1", "type": "synonym", "evidence": [ { "id": "XP_027270910", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270910" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270910" } ] }, { "annotation": "Involved in fertilization ability of sperm.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04#function" }, { "database": "UniProtKB", "id": "ARBA00003615", "url": "https://www.uniprot.org/uniprotkb/ARBA00003615#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Spesp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04", "locus": {} } ], "crossref": [ { "id": "A0A9J7FY04", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FY04", "database": "AlphaFoldDB", "categories": [] }, { "id": "100758358", "url": "https://www.ncbi.nlm.nih.gov/gene/100758358", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758358", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758358", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FY04", "url": "https://www.orthodb.org/?gene=A0A9J7FY04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31667", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31667", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31667:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31667:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270910", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270910", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FY04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY04-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCDYRCPWSCCVTDRLFRENTTLHLFSPERVPVTDQSNTCTEVQVAITVSPDEEQNLNHYVQVLQNLIMSVPTRDQGSDKKSEVSRTVEIAEPRSSPDLMLIHTPDEVTSEHDVLIRPVSEDKTTFPSSGFTLGMDGQKETESTAFWSIRPNNVSIVLHSDEPYIEKDEPEPEPEPELEVEPEARHIVPEPEPEPEPEFESEPESESHSEAEDSLEPDSRQNRMKTESSRMPSLIIHPWLGSTRVTLTTRASTMDVSTDTEDVPQLSGLLENEDIEEIAEHGSQNLRYEEILGKIYDIHSEILRGPLGDSNNPEYKEYIKASREHLKRSLALAAAAEHKLQQMYTSRIFPEDQMIDSADDMETVIDVLYNSRSKLSEYLNIKHIPTELRQKTTAVTGVLKRLLCVDQIEIQHLIRKLLSNNLKILNILDIP", "length": 431, "header": "tr|A0A9J7FY04-1|A0A9J7FY04_CRIGR Isoform 1 of Sperm equatorial segment protein 1 OS=Cricetulus griseus OX=10029 GN=Spesp1 PE=3 SV=1 CANONICAL=A0A9J7FY04-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FY04-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04/entry#A0A9J7FY04-1", "sequence": { "sequence": "MCDYRCPWSCCVTDRLFRENTTLHLFSPERVPVTDQSNTCTEVQVAITVSPDEEQNLNHYVQVLQNLIMSVPTRDQGSDKKSEVSRTVEIAEPRSSPDLMLIHTPDEVTSEHDVLIRPVSEDKTTFPSSGFTLGMDGQKETESTAFWSIRPNNVSIVLHSDEPYIEKDEPEPEPEPELEVEPEARHIVPEPEPEPEPEFESEPESESHSEAEDSLEPDSRQNRMKTESSRMPSLIIHPWLGSTRVTLTTRASTMDVSTDTEDVPQLSGLLENEDIEEIAEHGSQNLRYEEILGKIYDIHSEILRGPLGDSNNPEYKEYIKASREHLKRSLALAAAAEHKLQQMYTSRIFPEDQMIDSADDMETVIDVLYNSRSKLSEYLNIKHIPTELRQKTTAVTGVLKRLLCVDQIEIQHLIRKLLSNNLKILNILDIP", "length": 431, "header": "tr|A0A9J7FY04-1|A0A9J7FY04_CRIGR Isoform 1 of Sperm equatorial segment protein 1 OS=Cricetulus griseus OX=10029 GN=Spesp1 PE=3 SV=1 CANONICAL=A0A9J7FY04-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758358", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758358", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fusion of sperm to egg plasma membrane involved in single fertilization", "id": "GO:0007342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007342", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04" } ], "pmid": "" }, { "name": "acrosome reaction", "id": "GO:0007340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007340", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY04" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 20, "end_pos": 22 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FY10-1", "uniprot_ac": "A0A9J7FY10", "uniprot_id": "A0A9J7FY10_CRIGR", "mass": { "chemical_mass": 185135.0, "monoisotopic_mass": 185135.0 }, "refseq": { "ac": "XP_027271277", "name": "protein TOPAZ1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271277" }, "gene_names": [ { "name": "Topaz1", "type": "recommended", "evidence": [ { "id": "A0A9J7FY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY10" } ] }, { "name": "Topaz1", "type": "synonym", "evidence": [ { "id": "XP_027271277", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271277" } ] } ], "protein_names": [ { "name": "Protein TOPAZ1", "type": "recommended", "evidence": [ { "id": "A0A9J7FY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY10/entry#names_and_taxonomy" } ] }, { "name": "Testis- and ovary-specific PAZ domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7FY10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY10/entry#names_and_taxonomy" } ] }, { "name": "protein TOPAZ1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027271277", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271277" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271277" } ] }, { "annotation": "Important for normal spermatogenesis and male fertility. Specifically required for progression to the post-meiotic stages of spermatocyte development. Seems to be necessary for normal expression levels of a number of testis-expressed gene transcripts, although its role in this process is unclear.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY10#function" }, { "database": "UniProtKB", "id": "ARBA00002132", "url": "https://www.uniprot.org/uniprotkb/ARBA00002132#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY10" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Topaz1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY10", "locus": {} } ], "crossref": [ { "id": "100765807", "url": "https://www.ncbi.nlm.nih.gov/gene/100765807", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765807", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765807", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FY10", "url": "https://www.orthodb.org/?gene=A0A9J7FY10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35671:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35671:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271277", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FY10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY10-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPPTPPPGPATAPGREGDARGLRKRSLQLTPEPDKVGGCSLEARGREEESRQKRRAVAQASGGEATEGDKLAKEKGNISEAPSEDPQPGTDLVRKAALTSSESLQTVECSEFQNMAFLQSLAKEDLVEGIKRRIRIKKCKSLENLPLRITKNEAAQNTNVEFQDELYKNTPKYSCSSLSPGVEKHCSFESHDYSFLHSEGLNNENNFECKPHGVCMHIAENSLKLKKENLRSLAEKDGPETTAKLLKTEENVIASKLLLEESNLYQNKNNGLISCLQSEKSKYSIEESGIGRKHRKKVKLSEKEEKIIDLDFSNVNNNSELVLQENQMGAEGKETETSEPKKSFLKALRKINHNILSPVDHLCLPETVGKTSPKHQVNAVFQKTLESHLKEDIKNASESLGCRSVEPEDYFKSMISSAVKSPSDSHHMGKRSPWGDLRNETEESKVSCRRIIPMTGKRTWPFYSCARISVQCWKKTCLSDLNYPLPGSLENVRQHESVTHQTHLTDSKLLQQSLTERTIESSRKEMYDSGLNCLSSVSSVTPTLMVIKEAIPSDKKIKLEEPSRNGTEVVSSATEDTQLTNVTQSLTGNKKKRGNLSKLNLTMASQESQEANSFANKTIHRKACISKQTLVAPDLVKILNTGRLTNFKIPLLKNKMGKRKEVNSRSCEREAYSPLELLDSLSGVEAKQNRNKENICTATSGPQSLNVHSSVTPGEAGSHSFYNKTSCTAPSFAKKGYDNKAYSHISEPGNIISNKESISLKIENNTFSCDLGYIEQSSFCSEEQEAFVPISSEVSGRKMTKSISELKLGFPDILKAYEDDVLLIDVIQDDPELFGISSEGDLSFASEVSKISQEPSVSEEHPQADFKHMQLPGKKEPGDLSKEVALLDPGLLKLEICPSLSAAEESQRDPKGAAISLEAAEETIVSENLEDLSEQARASDSGAQCSSSDNAAAEEEQENTQEVCKSKESKDAEVVVNECQLAILGPKPLCSSVLPLKLSSHQENGVPMPWMNDFRFPGRPSSVLQLQNSETCEIFKREKNTGVFQKPLGLVIPHRYCKFHFNTLRGCERAQCKFVHVPEQGDEKICVDVFKKYISLDEQRLLQRAAHIFLEYYRKFPPGVHFSLQVLNDLLIALLKHCLLKEVFQVVKLSTMAKVLPALKILLKIFEYVAAMKLRNAVPALIEIFCKFIEAGMVPDSEHLNYIVKLLYQAQASHQDIAAVLEAKSRLRVRQLKKTWKCDLDSALSEVETCKEKGDWTKLGNLYISIKMGCEEFADFQRFCACVAESLTKDCKEEWPGVPFCEFAETVSKDPQFSEVDKTLLGRIGINAMYFYHRLMLWSKGRMVLDTLYELKIHFTSLKGLTGPEKVAPRCQIVNVAVEIFIKSGSLDGAIWVLRESEWIINTPLWPCDRMDVLNRHNLLCTIAHETLGKNLYRQTFEVLRNLPGFQNSQETVEVSQYSLLFNKLLDACIESSSLGISSSVAEFMVSKSIPIDFSFLRRLITALGRSCLWLKARAHYKSALSLGCYPPLEGNLYRKLLLVPSYLSEIEMLLAIEIFLVSNASSIQSPGTSTQMLQIVLKRCEESKSRSKDDYQAAVERLIMAARISDPKLFIKHMTVNINKEQVYSLEHCSALKWLKENMKWAGKVWLFTNH", 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LL00", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LL00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LL00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LL00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDW7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QDW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ68-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G129", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G129", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G129-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G129-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G253", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G253", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G253-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G253-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3F6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3F6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRM1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRM1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKSLDSDLSDGPVTVQEFMEVKSALVASEAKIQQLMKVNNNLSDELRIMQKKLQTLQCENSSLRKQATTSACQVQTGPDYPDTSSHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEANRPEEARTRLQPFPAHIGRSALVASSSSLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTPYGTEPDDTVSNRKGRQRSMVWQGDGSLPDTTEPHLVPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDTVRTSLRLLTSSAYRLQSECRKALPGDSSLPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN", "length": 760, "header": "tr|A0A9J7FYN1-1|A0A9J7FYN1_CRIGR Isoform 1 of ARF GTPase-activating protein GIT2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LL00-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1/entry#A0A8C2LL00-1", "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKLQTLQCENSSLRKQATTSACQVQTGPDYPDTSSHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEANRPEEARTRLQPFPAHIGRSALVASSSSLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTPYGTEPDDTVSNRKGRQRSMVWQGDGSLPDTTEPHLVPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDTVRTSLRLLTSSAYRLQSECRKALPGDSSLPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN", "length": 709, "header": "tr|A0A8C2LL00-1|A0A8C2LL00_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT2 isoform X16 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QDW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1/entry#A0A8C2QDW7-1", "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKSLDSDLSDGPVTVQEFMEVKSALVASEAKIQQLMKVNNNLSDELRIMQKKLQTLQCENSSLRKQATTSACQVQTGPDYPDTSSHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEANRPEEARTRLQPFPAHIGRSALVASSSSLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTPYGTEPDDTVSNRKGRQRSMVWQGDGSLPDTTEPHLVPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDTVRTSLRLLTSSAYRLQSECRKALPGDSSLPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN", "length": 759, "header": "tr|A0A8C2QDW7-1|A0A8C2QDW7_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT2 isoform X12 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FY24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1/entry#A0A9J7FY24-1", "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKSLDSDLSDGPVTVQEFMEVKSALVASEAKIQQLMKLQTLQCENSSLRKQATTSACQVQTGPDYPDTSSHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEANRPEEARTRLQPFPAHIGRSALVASSSSLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTPYGTEPDDTVSNRKGRQRSMVWQGDGSLPDTTEPHLVPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDTVRTSLRLLTSSAYRLQSECRKALPGDSSLPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN", "length": 745, "header": "tr|A0A9J7FY24-1|A0A9J7FYN1_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1/entry#A0A9J7FYN1-1", "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKSLDSDLSDGPVTVQEFMEVKSALVASEAKIQQLMKVNNNLSDELRIMQKKLQTLQCENSSLRKQATTSACQVQTGPDYPDTSSHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEANRPEEARTRLQPFPAHIGRSALVASSSSLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTPYGTEPDDTVSNRKGRQRSMVWQGDGSLPDTTEPHLVPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDTVRTSLRLLTSSAYRLQSECRKALPGDSSLPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN", "length": 760, "header": "tr|A0A9J7FYN1-1|A0A9J7FYN1_CRIGR Isoform 1 of ARF GTPase-activating protein GIT2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1/entry#A0A9J7FYY1-1", "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKLLGSDAN", "length": 422, "header": "tr|A0A9J7FYY1-1|A0A9J7FYY1_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT2 isoform X20 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZ68-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1/entry#A0A9J7FZ68-1", "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKSLDSDLSDGPVTVQEFMEVKSALVASEAKIQQLMKVNNNLSDELRIMQKKLLGSDAN", "length": 472, "header": "tr|A0A9J7FZ68-1|A0A9J7FZ68_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT2 isoform X18 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G129-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1/entry#A0A9J7G129-1", "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKLQTLQCENSSLRKQATTSACQVQTGPDYPDTSSHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEANRPEEARTRLQPFPAHASRLEKQNSTPESDYDNTPYGTEPDDTVSNRKGRQRSMVWQGDGSLPDTTEPHLVPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDTVRTSLRLLTSSAYRLQSECRKALPGDSSLPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN", "length": 680, "header": "tr|A0A9J7G129-1|A0A9J7G129_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT2 isoform X17 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G253-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1/entry#A0A9J7G253-1", "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKSLDSDLSDGPVTVQEFMEVKSALVASEAKIQQLMKVNNNLSDELRIMQKKLQTLQCENSSLRKQATTSACQVQTGPDYPDTSSHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEANRPEEARTRLQPFPAHASRLEKQNSTPESDYDNTPYGTEPDDTVSNRKGRQRSMVWQGDGSLPDTTEPHLVPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDTVRTSLRLLTSSAYRLQSECRKALPGDSSLPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN", "length": 730, "header": "tr|A0A9J7G253-1|A0A9J7G253_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT2 isoform X14 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3F6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1/entry#A0A9J7G3F6-1", "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKSLDSDLSDGPVTVQEFMEVKSALVASEAKIQQLMKLLGSDAN", "length": 457, "header": "tr|A0A9J7G3F6-1|A0A9J7G3F6_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT2 isoform X19 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1/entry#A0A9J7JRM1-1", "sequence": { "sequence": "MSKRLRSSDVCADCSGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDVSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQQGSPLSRSQDNVELILRTVSNQHSTESQDNDQPDYDSVASDEDTDVETRASKAHRQKLQTLQCENSSLRKQATTSACQVQTGPDYPDTSSHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEANRPEEARTRLQPFPAHIGRSALVASSSSLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTPYGTEPDDTVSNRKGRQRSMVWQGDGSLPDTTEPHLVPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDTVRTSLRLLTSSAYRLQSECRKALPGDSSLPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN", "length": 710, "header": "tr|A0A9J7JRM1-1|A0A9J7JRM1_CRIGR Computationally mapped isoform of ARF GTPase-activating protein GIT2 isoform X15 OS=Cricetulus griseus OX=10029 GN=Git2 PE=4 SV=1 CANONICAL=A0A9J7FYN1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY24" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY24" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756931", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756931", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYN1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": 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This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271095", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271095" } ] }, { "annotation": "Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62#function" }, { "database": "UniProtKB", "id": "ARBA00060157", "url": "https://www.uniprot.org/uniprotkb/ARBA00060157#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Crtap", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62", "locus": {} } ], "crossref": [ { "id": "A0A9J7FY62", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FY62", "database": "AlphaFoldDB", "categories": [] }, { "id": "100767159", "url": "https://www.ncbi.nlm.nih.gov/gene/100767159", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767159", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767159", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FY62", "url": "https://www.orthodb.org/?gene=A0A9J7FY62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13986", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13986", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13986:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13986:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271095", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271095", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FY62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSHVPQAGLEVAKVLRLHLSDSRAELLPQDTPIAVPGRGGLPDRAGHGRRPRLPSRACRVARPPLWARVSGPRAMGSRAAAWLMLLCAGCALPPGLAQYERYSFRSFPRDELMPLESAYRHALDQYGGEHWAESVSYLEVSLRLHRLLRDSEAFCHRNCSAAPPAPAPAGPASHAELRLFGGVLRRAQCLKRCKQGLPAFRQSQPSRAVLADFQQREPYKFLQFAYFKANDLPKAIAAAHTYLLKHPDDEMMKRNMAYYKSLPGAEDHIKDLETKSYENLFVRAVRAYNGENWRTSVMDMELALPDFFKAFYECLASCEGSREIKDFKDFYLSIADHYVEVLECKIQCEENLTPVIGGYRVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDKDDKVMQQNLVYYQYHRDKWGLSDEHFQPRPEAVQFVNVTMLQKELYSFAQEHLMDDDEGEVVEYVDDLLEMEEAG", "length": 473, "header": "tr|A0A9J7FY62-1|A0A9J7FY62_CRIGR Isoform 1 of Cartilage-associated protein OS=Cricetulus griseus OX=10029 GN=Crtap PE=3 SV=1 CANONICAL=A0A9J7FY62-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FY62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62/entry#A0A9J7FY62-1", "sequence": { "sequence": "MGSHVPQAGLEVAKVLRLHLSDSRAELLPQDTPIAVPGRGGLPDRAGHGRRPRLPSRACRVARPPLWARVSGPRAMGSRAAAWLMLLCAGCALPPGLAQYERYSFRSFPRDELMPLESAYRHALDQYGGEHWAESVSYLEVSLRLHRLLRDSEAFCHRNCSAAPPAPAPAGPASHAELRLFGGVLRRAQCLKRCKQGLPAFRQSQPSRAVLADFQQREPYKFLQFAYFKANDLPKAIAAAHTYLLKHPDDEMMKRNMAYYKSLPGAEDHIKDLETKSYENLFVRAVRAYNGENWRTSVMDMELALPDFFKAFYECLASCEGSREIKDFKDFYLSIADHYVEVLECKIQCEENLTPVIGGYRVEKFVATMYHYLQFAYYKLNDLKNAAPCAVSYLLFDKDDKVMQQNLVYYQYHRDKWGLSDEHFQPRPEAVQFVNVTMLQKELYSFAQEHLMDDDEGEVVEYVDDLLEMEEAG", "length": 473, "header": "tr|A0A9J7FY62-1|A0A9J7FY62_CRIGR Isoform 1 of Cartilage-associated protein OS=Cricetulus griseus OX=10029 GN=Crtap PE=3 SV=1 CANONICAL=A0A9J7FY62-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767159", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767159", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FY62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY62" }, { "id": "PF23557", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23557" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Leprecan-like alpha-helical", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 414, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 435, "end_pos": 437 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G0D3-1", "uniprot_ac": "A0A9J7G0D3", "uniprot_id": "A0A9J7G0D3_CRIGR", "mass": { "chemical_mass": 162057.0, "monoisotopic_mass": 162057.0 }, "refseq": { "ac": "XP_027271243", "name": "NK-tumor recognition protein isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271243" }, "gene_names": [ { "name": "Nktr", "type": "recommended", "evidence": [ { "id": "A0A9J7G0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3" } ] }, { "name": "Nktr", "type": "synonym", "evidence": [ { "id": "XP_027271243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271243" } ] } ], "protein_names": [ { "name": "peptidylprolyl isomerase", "type": "recommended", "evidence": [ { "id": "A0A9J7G0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3/entry#names_and_taxonomy" } ] }, { "name": "5.2.1.8", "type": "synonym", "evidence": [ { "id": "A0A9J7G0D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3/entry#names_and_taxonomy" } ] }, { "name": "NK-tumor recognition protein isoform X5", "type": "synonym", "evidence": [ { "id": "XP_027271243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271243" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271243" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nktr", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3", "locus": {} } ], "crossref": [ { "id": "100767554", "url": "https://www.ncbi.nlm.nih.gov/gene/100767554", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767554", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767554", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0D3", "url": "https://www.orthodb.org/?gene=A0A9J7G0D3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11071:SF257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11071:SF257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16237", "url": "https://www.rhea-db.org/rhea/16237", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LE45", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LE45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY80", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY80-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0D3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2P6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWR9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAQDRPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRVVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFITTKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKLTKDVFEKKRKKPTHSEDSDSSCNSSSSSESSSESGVEQERVRKRRHKRRPKVRHTKKRRKEVSSSEGPRGRRTVSPEGYSGRSDVNEKGSGDWSAKREKPVVRPEEIPPVPENRFLLRRDMPAVTVEPEPNIPDVAPVVSDQKPSVSKSGRKIRGRGTIRYHTPPRSRSHSESEDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGCYSDLSTARHSDGHHKKRRKEKKFKHKKKAKKQKHCRRHRQTKKRRLVVPSDLGPSRPSTHRRKSSCDRGRRSRASPSSSSSSHHSSKRDWSKSDRGDRSSSTHSSRNSYRSKSHSRSDSRGSSRSRALSKSRSSSRSGRRRTASKSPKKPPHLSDNKPVKTEPLRASMPQNGSVLVQPVAAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPVQSTYSLTNIKETRSSSSYHKRGKNSESDGSAYSKYSDRSSRGSGRSGDRSSRSRSSSRSYTRSRSRSPPTSRSQSRSLSSRSRSQNKYSDVSQRSRSSSYTSVSSDDGRRATRTFRSSGEKSITTNKRHCSSSKKILHSKYVKGREKSCHRRYSESRSSLDYSSDSEQSHVHGVHSAPERKPGKIEVLNDKQGKNREEGKSKPEWEKRALKESLSDQSRDGSQSRGKHCAGSKWDSESNSEQDVTKNRKSDSRRCSDKEEGEASSDSEPEVGQSHLKLPAKPSSNTSLPDSNGAWKSRRPQSSASESEGSCLNLGNIRMEPQKQKCPKDSSLKGDHTKKVREKLKDKEVRKHKAPKRKQAFHWQPPLEFGDEEEEEVSREQVPQEPEEKRETGKDTIPKVEKTCNEGSCPRNPKKETAEHDPLAEGDHTPSSCPAPLKVEENATSSPASAQHIEEHVPGGGEDVLQTDDNMEICTPERSSPTKGEGVSPLENHRLDSPEVSIIPEQVEHVTQPRAGGKQESIVSESKTSNEGGKQDSSASLASPVEIAGKKEGTEKNHMNLTDKWKPLQGVGNLAVPTATTSSALDVKPSAPVPDVKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDGNSQSRSPHRSRSKSETKSRHRTRSVSYSQSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYGSFHSHRTSSRSRSRSSSYDPHSRSSRSYSYDSYYSRSRSHSRSQRSDSYHRGRSYNRRSRSGRSYGSDSESDRSYSRHRSPSESSRYS", "length": 1441, "header": "tr|A0A9J7G0D3-1|A0A9J7G0D3_CRIGR Isoform 1 of peptidylprolyl isomerase OS=Cricetulus griseus OX=10029 GN=Nktr PE=4 SV=1 CANONICAL=A0A9J7G0D3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LE45-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3/entry#A0A8C2LE45-1", "sequence": { "sequence": "MGAQDRPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRVVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFITTKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKLTKDVFEKKRKKPTHSEDSDSSCNSSSSSESSSESGVEQERVRKRRHKRRPKVRHTKKRRKEVSSSEGPRGRRTVSPEGYSGRSDVNEKGSGDWSAKREKPVVRPEEIPPVPENRFLLRRDMPAVTVEPEPNIPDVAPVVSDQKPSVSKSGRKIRGRGTIRYHTPPRSRSHSESEDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGCYSDLSTARHSDGHHKKRRKEKKFKHKKKAKKQKHCRRHRQTKKRRLVVPSDLGPSRPSTHRRKSSCDRGRRSRASPSSSSSSHHSSKRDWSKSDRGDRSSSTHSSRNSYRSKSHSRSDSRGSSRSRALSKSRSSSRSGRRRTASKSPKKPPHLSDNKPVKTEPLRASMPQNGSVLVQPVAAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPVQSTYSLTNIKETRSSSSYHKRGKNSESDGSAYSKYSDRSSRGSGRSGDRSSRSRSSSRSYTRSRSRSPPTSRSQSRSLSSRSRSQNKYSDVSQRSRSSSYTSVSSDDGRRATRTFRSSGEKSITTNKRHCSSSKKILHSKYVKGREKSCHRRYSESRSSLDYSSDSEQSHVHGVHSAPERKPGKIEVLNDKQGKNREEGKSKPEWEKRALKESLSDQSRDGSQSRGKHCAGSKWDSESNSEQDVTKNRKSDSRRCSDKEEGEASSDSEPEVGQSHLKLPAKPSSNTSLPDSNGAWKSRRPQSSASESEGSCLNLGNIRMEPQKQKCPKDSSLKGDHTKKVREKLKDKEVRKHKAPKRKQAFHWQPPLEFGDEEEEEVSREQVPQEPEEKRETGKDTIPKVEKTCNEGSCPRNPKKETAEHDPLAEGDHTPSSCPAPLKVEENATSSPASAQHIEEHVPGGGEDVLQTDDNMEICTPERSSPTKGEGVSPLENHRLDSPEVSIIPEQVEHVTQPRAGGKQESIVSESKTSNEGGKQDSSASLASPVEIAGKKEGTEKNHMNLTDKWKPLQGVGNLAVPTATTSSALDVKPSAPVPDVKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDGNSQSRSPHRSRSKSETKSRHRTRSVSYSQSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYGSFHSHRTSSRSRSRSSSYDPHSRSRSYSYDSYYSRSRSHSRSQRSDSYHRGRSYNRRSRSGRSYGSDSESDRSYSRHRSPSESSRYS", "length": 1440, "header": "tr|A0A8C2LE45-1|A0A8C2LE45_CRIGR Computationally mapped isoform of peptidylprolyl isomerase OS=Cricetulus griseus OX=10029 GN=Nktr PE=4 SV=1 CANONICAL=A0A9J7G0D3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FY80-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3/entry#A0A9J7FY80-1", "sequence": { "sequence": "MANRGKHTNGSQFFITTKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKLTKDVFEKKRKKPTHSEDSDSSCNSSSSSESSSESGVEQERVRKRRHKRRPKVRHTKKRRKEVSSSEGPRGRRTVSPEGYSGRSDVNEKGSGDWSAKREKPVVRPEEIPPVPENRFLLRRDMPAVTVEPEPNIPDVAPVVSDQKPSVSKSGRKIRGRGTIRYHTPPRSRSHSESEDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGCYSDLSTARHSDGHHKKRRKEKKFKHKKKAKKQKHCRRHRQTKKRRLVVPSDLGPSRPSTHRRKSSCDRGRRSRASPSSSSSSHHSSKRDWSKSDRGDRSSSTHSSRNSYRSKSHSRSDSRGSSRSRALSKSRSSSRSGRRRTASKSPKKPPHLSDNKPVKTEPLRASMPQNGSVLVQPVAAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPVQSTYSLTNIKETRSSSSYHKRGKNSESDGSAYSKYSDRSSRGSGRSGDRSSRSRSSSRSYTRSRSRSPPTSRSQSRSLSSRSRSQNKYSDVSQRSRSSSYTSVSSDDGRRATRTFRSSGEKSITTNKRHCSSSKKILHSKYVKGREKSCHRRYSESRSSLDYSSDSEQSHVHGVHSAPERKPGKIEVLNDKQGKNREEGKSKPEWEKRALKESLSDQSRDGSQSRGKHCAGSKWDSESNSEQDVTKNRKSDSRRCSDKEEGEASSDSEPEVGQSHLKLPAKPSSNTSLPDSNGAWKSRRPQSSASESEGSCLNLGNIRMEPQKQKCPKDSSLKGDHTKKVREKLKDKEVRKHKAPKRKQAFHWQPPLEFGDEEEEEVSREQVPQEPEEKRETGKDTIPKVEKTCNEGSCPRNPKKETAEHDPLAEGDHTPSSCPAPLKVEENATSSPASAQHIEEHVPGGGEDVLQTDDNMEICTPERSSPTKGEGVSPLENHRLDSPEVSIIPEQVEHVTQPRAGGKQESIVSESKTSNEGGKQDSSASLASPVEIAGKKEGTEKNHMNLTDKWKPLQGVGNLAVPTATTSSALDVKPSAPVPDVKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDGNSQSRSPHRSRSKSETKSRHRTRSVSYSQSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYGSFHSHRTSSRSRSRSSSYDPHSRSSRSYSYDSYYSRSRSHSRSQRSDSYHRGRSYNRRSRSGRSYGSDSESDRSYSRHRSPSESSRYS", "length": 1331, "header": "tr|A0A9J7FY80-1|A0A9J7FY80_CRIGR Computationally mapped isoform of NK-tumor recognition protein isoform X9 OS=Cricetulus griseus OX=10029 GN=Nktr PE=4 SV=1 CANONICAL=A0A9J7G0D3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G0D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3/entry#A0A9J7G0D3-1", "sequence": { "sequence": "MGAQDRPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRVVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFITTKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKLTKDVFEKKRKKPTHSEDSDSSCNSSSSSESSSESGVEQERVRKRRHKRRPKVRHTKKRRKEVSSSEGPRGRRTVSPEGYSGRSDVNEKGSGDWSAKREKPVVRPEEIPPVPENRFLLRRDMPAVTVEPEPNIPDVAPVVSDQKPSVSKSGRKIRGRGTIRYHTPPRSRSHSESEDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGCYSDLSTARHSDGHHKKRRKEKKFKHKKKAKKQKHCRRHRQTKKRRLVVPSDLGPSRPSTHRRKSSCDRGRRSRASPSSSSSSHHSSKRDWSKSDRGDRSSSTHSSRNSYRSKSHSRSDSRGSSRSRALSKSRSSSRSGRRRTASKSPKKPPHLSDNKPVKTEPLRASMPQNGSVLVQPVAAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPVQSTYSLTNIKETRSSSSYHKRGKNSESDGSAYSKYSDRSSRGSGRSGDRSSRSRSSSRSYTRSRSRSPPTSRSQSRSLSSRSRSQNKYSDVSQRSRSSSYTSVSSDDGRRATRTFRSSGEKSITTNKRHCSSSKKILHSKYVKGREKSCHRRYSESRSSLDYSSDSEQSHVHGVHSAPERKPGKIEVLNDKQGKNREEGKSKPEWEKRALKESLSDQSRDGSQSRGKHCAGSKWDSESNSEQDVTKNRKSDSRRCSDKEEGEASSDSEPEVGQSHLKLPAKPSSNTSLPDSNGAWKSRRPQSSASESEGSCLNLGNIRMEPQKQKCPKDSSLKGDHTKKVREKLKDKEVRKHKAPKRKQAFHWQPPLEFGDEEEEEVSREQVPQEPEEKRETGKDTIPKVEKTCNEGSCPRNPKKETAEHDPLAEGDHTPSSCPAPLKVEENATSSPASAQHIEEHVPGGGEDVLQTDDNMEICTPERSSPTKGEGVSPLENHRLDSPEVSIIPEQVEHVTQPRAGGKQESIVSESKTSNEGGKQDSSASLASPVEIAGKKEGTEKNHMNLTDKWKPLQGVGNLAVPTATTSSALDVKPSAPVPDVKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDGNSQSRSPHRSRSKSETKSRHRTRSVSYSQSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYGSFHSHRTSSRSRSRSSSYDPHSRSSRSYSYDSYYSRSRSHSRSQRSDSYHRGRSYNRRSRSGRSYGSDSESDRSYSRHRSPSESSRYS", "length": 1441, "header": "tr|A0A9J7G0D3-1|A0A9J7G0D3_CRIGR Isoform 1 of peptidylprolyl isomerase OS=Cricetulus griseus OX=10029 GN=Nktr PE=4 SV=1 CANONICAL=A0A9J7G0D3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3/entry#A0A9J7G2P6-1", "sequence": { "sequence": "MGAQDRPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRVVKNFMIQGGDFSEGNGKGGESIYGGYFKENVVFCKMKRTTKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKLTKDVFEKKRKKPTHSEDSDSSCNSSSSSESSSESGVEQERVRKRRHKRRPKVRHTKKRRKEVSSSEGPRGRRTVSPEGYSGRSDVNEKGSGDWSAKREKPVVRPEEIPPVPENRFLLRRDMPAVTVEPEPNIPDVAPVVSDQKPSVSKSGRKIRGRGTIRYHTPPRSRSHSESEDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGCYSDLSTARHSDGHHKKRRKEKKFKHKKKAKKQKHCRRHRQTKKRRLVVPSDLGPSRPSTHRRKSSCDRGRRSRASPSSSSSSHHSSKRDWSKSDRGDRSSSTHSSRNSYRSKSHSRSDSRGSSRSRALSKSRSSSRSGRRRTASKSPKKPPHLSDNKPVKTEPLRASMPQNGSVLVQPVAAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPVQSTYSLTNIKETRSSSSYHKRGKNSESDGSAYSKYSDRSSRGSGRSGDRSSRSRSSSRSYTRSRSRSPPTSRSQSRSLSSRSRSQNKYSDVSQRSRSSSYTSVSSDDGRRATRTFRSSGEKSITTNKRHCSSSKKILHSKYVKGREKSCHRRYSESRSSLDYSSDSEQSHVHGVHSAPERKPGKIEVLNDKQGKNREEGKSKPEWEKRALKESLSDQSRDGSQSRGKHCAGSKWDSESNSEQDVTKNRKSDSRRCSDKEEGEASSDSEPEVGQSHLKLPAKPSSNTSLPDSNGAWKSRRPQSSASESEGSCLNLGNIRMEPQKQKCPKDSSLKGDHTKKVREKLKDKEVRKHKAPKRKQAFHWQPPLEFGDEEEEEVSREQVPQEPEEKRETGKDTIPKVEKTCNEGSCPRNPKKETAEHDPLAEGDHTPSSCPAPLKVEENATSSPASAQHIEEHVPGGGEDVLQTDDNMEICTPERSSPTKGEGVSPLENHRLDSPEVSIIPEQVEHVTQPRAGGKQESIVSESKTSNEGGKQDSSASLASPVEIAGKKEGTEKNHMNLTDKWKPLQGVGNLAVPTATTSSALDVKPSAPVPDVKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDGNSQSRSPHRSRSKSETKSRHRTRSVSYSQSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYGSFHSHRTSSRSRSRSSSYDPHSRSSRSYSYDSYYSRSRSHSRSQRSDSYHRGRSYNRRSRSGRSYGSDSESDRSYSRHRSPSESSRYS", "length": 1421, "header": "tr|A0A9J7G2P6-1|A0A9J7G2P6_CRIGR Computationally mapped isoform of peptidylprolyl isomerase OS=Cricetulus griseus OX=10029 GN=Nktr PE=4 SV=1 CANONICAL=A0A9J7G0D3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3/entry#A0A9J7GWR9-1", "sequence": { "sequence": "MGAQDRPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRVVKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGKHTNGSQFFITTKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKLTKDVFEKKRKKPTHSEDSDSSCNSSSSSESSSESGVEQERVRKRRHKRRPKVRHTKKRRKEVSSSEGPRGRRTVSPEGYSGRSDVNEKGSGDWSAKREKPVVRPEEIPPVPENRFLLRRDMPAVTVEPEPNIPDVAPVVSDQKPSVSKSGRKIRGRGTIRYHTPPRSRSHSESEDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGCYSDLSTARHSDGHHKKRRKEKKFKHKKKAKKQKHCRRHRQTKKRRLVVPSDLGPSRPSTHRRKSSCDRGRRSRASPSSSSSSHHSSKRDWSKSDRGDRSSSTHSSRNSYRSKSHSRSDSRGSSRSRALSKSRSSSRSGRRRTASKSPKKPPHLSDNKPVKTEPLRASMPQNGSVLVQPVAAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPVQSTYSLTNIKETRSSSSYHKRGKNSESDGSAYSKYSDRSSRGSGRSGDRSSRSRSSSRSYTRSRSRSPPTSRSQSRSLSSRSRSQNKYSDVSQRSRSSSYTSVSSDDGRRATRTFRSSGEKSITTNKRHCSSSKKILHSKYVKGREKSCHRRYSESRSSLDYSSDSEQSHVHGVHSAPERKPGKIEVLNDKQGKNREEGKSKPEWEKRALKESLSDQSRDGSQSRGKHCAGSKWDSESNSEQDVTKNRKSDSRRCSDKEEGEASSDSEPEVGQSHLKLPAKPSSNTSLPDSNGAWKSRRPQSSASESEGSCLNLGNIRMEPQKQKCPKDSSLKGDHTKKVREKLKDKEVRKHKAPKRKQAFHWQPPLEFGDEEEEEVSREQVPQEPEEKRETGKDTIPKVEKTCNEGSCPRNPKKETAEHDPLAEGDHTPSSCPAPLKVEENATSSPASAQHIEEHVPGGGEDVLQTDDNMEICTPERSSPTKGEGVSPLENHRLDSPEVSIIPEQVEHVTQPRAGGKQESIVSESKTSNEGGKQDSSASLASPVEIAGKKEGTEKNHMNLTDKWKPLQGVGNLAVPTATTSSALDVKPSAPVPDVKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDGNSQSRSPHRSRSKSETKSRHRTRSVSYSQSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYGSFHSHRTSSRSRSRSSSYDPHSRSRKEINIFLFNMVSPTGGNCWMCLELLMQLSSYLHRVPV", "length": 1415, "header": "tr|A0A9J7GWR9-1|A0A9J7GWR9_CRIGR Computationally mapped isoform of peptidylprolyl isomerase OS=Cricetulus griseus OX=10029 GN=Nktr PE=4 SV=1 CANONICAL=A0A9J7G0D3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767554", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767554", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0D3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0D3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cyclosporin A binding", "id": "GO:0016018", "url": 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annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007642745", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642745" } ] }, { "annotation": "Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81#function" }, { "database": "UniProtKB", "id": "ARBA00002691", "url": "https://www.uniprot.org/uniprotkb/ARBA00002691#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": 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[ "Protein Classification" ] }, { "id": "PF01301", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01301", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007642745", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642745", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FY81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY81-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVFFLPLVLAGLAPLSEYKNALFKMSATRFSWSRLTPFKLKNRSVGLSTESNAQGKVYFTLDGHKFMIVGGSIHYFRVPREYWKDRLLKLQACGFNTVTTYIPWNLHEQNRGTFDFSEILDLEAYVSLAATLGLWVILRPGPYICAEVDLGGLPSWLLGYPELQLRTTQQEFLDAVDKYFDHLIPRILPLQYLRGGPVIAVQIENEYGSFSKDGDYMEYIKEALQKRGIVELLLTSDNHKGIQTGSVKGALTTINMASFEKDSFIKLLQMQNDKPIMVMEYWTGWFDTWGREHNVKSAEEIRYTVSRFIKYGISFNMYMFHGGTNFGFINGAFHYDKHSSVVTSYDYDAVLTEAGDYTEKYFKLRKLFASASVGFLPRLPQLIPKTVYPTVGLAFYLPLFDILPYLNKPVMLYTPVTMENLPINNGSGQPFGFVLYETSICAGGDLYASVSDSAQVFLNDTTIGNLDEYTYDLTIPTIQDCQLLRILVENQGRINYSWKIQNEWKGLNGDISINGTLLKNFTIYSLDMKMSFFERLRSATWRLAPENYLGPAFYLGTLKADSSPKDTFLDLSNWYYGFVFINGRNLGRYQNIGPQRTLYLPGPWLHPGDNEIIVFEKIQKGFYIQSKTRPQLQY", "length": 635, "header": "tr|A0A9J7FY81-1|A0A9J7FY81_CRIGR Isoform 1 of Beta-galactosidase OS=Cricetulus griseus OX=10029 GN=Glb1l3 PE=3 SV=1 CANONICAL=A0A9J7FY81-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FY81-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81/entry#A0A9J7FY81-1", "sequence": { "sequence": "MAVFFLPLVLAGLAPLSEYKNALFKMSATRFSWSRLTPFKLKNRSVGLSTESNAQGKVYFTLDGHKFMIVGGSIHYFRVPREYWKDRLLKLQACGFNTVTTYIPWNLHEQNRGTFDFSEILDLEAYVSLAATLGLWVILRPGPYICAEVDLGGLPSWLLGYPELQLRTTQQEFLDAVDKYFDHLIPRILPLQYLRGGPVIAVQIENEYGSFSKDGDYMEYIKEALQKRGIVELLLTSDNHKGIQTGSVKGALTTINMASFEKDSFIKLLQMQNDKPIMVMEYWTGWFDTWGREHNVKSAEEIRYTVSRFIKYGISFNMYMFHGGTNFGFINGAFHYDKHSSVVTSYDYDAVLTEAGDYTEKYFKLRKLFASASVGFLPRLPQLIPKTVYPTVGLAFYLPLFDILPYLNKPVMLYTPVTMENLPINNGSGQPFGFVLYETSICAGGDLYASVSDSAQVFLNDTTIGNLDEYTYDLTIPTIQDCQLLRILVENQGRINYSWKIQNEWKGLNGDISINGTLLKNFTIYSLDMKMSFFERLRSATWRLAPENYLGPAFYLGTLKADSSPKDTFLDLSNWYYGFVFINGRNLGRYQNIGPQRTLYLPGPWLHPGDNEIIVFEKIQKGFYIQSKTRPQLQY", "length": 635, "header": "tr|A0A9J7FY81-1|A0A9J7FY81_CRIGR Isoform 1 of Beta-galactosidase OS=Cricetulus griseus OX=10029 GN=Glb1l3 PE=3 SV=1 CANONICAL=A0A9J7FY81-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 391, "start_aa": "Thr", "end_pos": 391, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr391", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757469", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757469", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "beta-galactosidase activity", "id": "GO:0004565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FY81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81" }, { "id": "PF21317", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21317" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-galactosidase 1-like first all-beta", "eco_id": "ECO_0000259", "start_pos": 416, "end_pos": 528, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FY81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81" }, { "id": "PF21467", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21467" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Beta-galactosidase galactose-binding", "eco_id": "ECO_0000259", "start_pos": 552, "end_pos": 611, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FY81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY81" }, { "id": "PF01301", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01301" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoside hydrolase 35 catalytic", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 370, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.2.1.23", "ec_name": "Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.", "evidence": [ { "id": "3.2.1.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.2.1.23" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 391 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 426, "end_pos": 428 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 521, "end_pos": 523 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, 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Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271422", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271422" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FY83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY83" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Clic6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY83", "locus": {} } ], "crossref": [ { "id": "A0A9J7FY83", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FY83", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03061", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03061", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10301", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10301", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757995", "url": "https://www.ncbi.nlm.nih.gov/gene/100757995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757995", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757995", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FY83", "url": "https://www.orthodb.org/?gene=A0A9J7FY83", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45476", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45476", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45476:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45476:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13410", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13410", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271422", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271422", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29823", "url": "https://www.rhea-db.org/rhea/29823", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FY83", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY83-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAAEPKEVAQGPQGQPEGARIEGLGEPGAADPEGQAASKGAAETPADQGAGAEATASGKEEGGSGQDGGIGGARTETPSASGAQGEAEAAERDPEGAGLLPGAEEEPGAQPVRERSPGLDQQGEVPEVPEDDRQQPEDPTTSEAWKEVESSLEAQGGSAPGSQITTEAQGPAGESMDTDAPAGEAHGSEGEPRGGGESSPQPQAEATEVAASEIGGHDPGELAGAPAEDASGEAGAPGKDGSEEAAPEEARVDAGENGKQGGLQEETGEEEARPEPRLEGRCEEGIQEKPSDGSPDEEEAKATGQEESQVELSNHLAEEPSAQGGEELERVNDGRENGPASEVEDPGQEHDITLFVKAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLVPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTRKDANEIYEKNLLRALKKLDSYLNSPLPDEIDAYSTEDVAVSRRKFLDGDELTLADCNLLPKLHIIKIVAKKYRGFEFPSEMTGIWRYLNNAYARDEFTNTCPADREIEHAYSDAAKRMK", "length": 587, "header": "tr|A0A9J7FY83-1|A0A9J7FY83_CRIGR Isoform 1 of Chloride intracellular channel protein OS=Cricetulus griseus OX=10029 GN=Clic6 PE=3 SV=1 CANONICAL=A0A9J7FY83-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FY83-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY83/entry#A0A9J7FY83-1", "sequence": { "sequence": "MAEAAEPKEVAQGPQGQPEGARIEGLGEPGAADPEGQAASKGAAETPADQGAGAEATASGKEEGGSGQDGGIGGARTETPSASGAQGEAEAAERDPEGAGLLPGAEEEPGAQPVRERSPGLDQQGEVPEVPEDDRQQPEDPTTSEAWKEVESSLEAQGGSAPGSQITTEAQGPAGESMDTDAPAGEAHGSEGEPRGGGESSPQPQAEATEVAASEIGGHDPGELAGAPAEDASGEAGAPGKDGSEEAAPEEARVDAGENGKQGGLQEETGEEEARPEPRLEGRCEEGIQEKPSDGSPDEEEAKATGQEESQVELSNHLAEEPSAQGGEELERVNDGRENGPASEVEDPGQEHDITLFVKAGYDGESIGNCPFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLVPPRYPKLGTQHPESNSAGNDVFAKFSAFIKNTRKDANEIYEKNLLRALKKLDSYLNSPLPDEIDAYSTEDVAVSRRKFLDGDELTLADCNLLPKLHIIKIVAKKYRGFEFPSEMTGIWRYLNNAYARDEFTNTCPADREIEHAYSDAAKRMK", "length": 587, "header": "tr|A0A9J7FY83-1|A0A9J7FY83_CRIGR Isoform 1 of Chloride intracellular channel protein OS=Cricetulus griseus OX=10029 GN=Clic6 PE=3 SV=1 CANONICAL=A0A9J7FY83-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": 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This record is derived from a genomic sequence (NW_003614046.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504273" } ] }, { "annotation": "Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA5#function" }, { "database": "UniProtKB", "id": "ARBA00060053", "url": "https://www.uniprot.org/uniprotkb/ARBA00060053#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100756347", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA5", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYA5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYA5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05251", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05251", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756347", "url": "https://www.ncbi.nlm.nih.gov/gene/100756347", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756347", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756347", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FYA5", "url": "https://www.orthodb.org/?gene=A0A9J7FYA5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42748", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42748", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42748:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42748:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05368", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05368", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504273", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FYA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANRKIIAVFGATGAQGGSVARAILENNHFALRALTRDVTGKKAQVFQDLGAEVVRCDLDDPASVEEALKGVYGAFVVTNFWDHHSKEKEACQGKLVADVAKRLGLKHVVYSGLENVDRLTGGKLKVLHFDGKGEVEEYFWSIGVPMTSVRLAAYFENFLTLWKPVKTSEGHYTLALPMGDVPMDGISVADVGAVVSSIFASPEEFVGKAVGLSAEALTIQQYADILSKTLGKDIRDAKITLEAFEKMGFPGVEEMASMFRFYHMKPDRDIKLTHRLNPKIRSFSQFISENQGAFKDL", "length": 298, "header": "tr|A0A9J7FYA5-1|A0A9J7FYA5_CRIGR Isoform 1 of NmrA-like family domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=LOC100756347 PE=3 SV=1 CANONICAL=A0A9J7FYA5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA5/entry#A0A9J7FYA5-1", "sequence": { "sequence": "MANRKIIAVFGATGAQGGSVARAILENNHFALRALTRDVTGKKAQVFQDLGAEVVRCDLDDPASVEEALKGVYGAFVVTNFWDHHSKEKEACQGKLVADVAKRLGLKHVVYSGLENVDRLTGGKLKVLHFDGKGEVEEYFWSIGVPMTSVRLAAYFENFLTLWKPVKTSEGHYTLALPMGDVPMDGISVADVGAVVSSIFASPEEFVGKAVGLSAEALTIQQYADILSKTLGKDIRDAKITLEAFEKMGFPGVEEMASMFRFYHMKPDRDIKLTHRLNPKIRSFSQFISENQGAFKDL", "length": 298, "header": "tr|A0A9J7FYA5-1|A0A9J7FYA5_CRIGR Isoform 1 of NmrA-like family domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=LOC100756347 PE=3 SV=1 CANONICAL=A0A9J7FYA5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FYA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYA5" }, { "id": "PF05368", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05368" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NmrA-like", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 265, "start_aa": "Lys", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, 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"UniProtKB", "id": "A0A9J7FYB8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYB8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYB8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FYB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYB8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FYC3-1", "uniprot_ac": "A0A9J7FYC3", "uniprot_id": "A0A9J7FYC3_CRIGR", "mass": { "chemical_mass": 98936.0, "monoisotopic_mass": 98936.0 }, "refseq": { "ac": "XP_027271230", "name": "trafficking kinesin-binding protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271230" }, "gene_names": [ { "name": "Trak1", "type": "recommended", "evidence": [ { "id": "A0A9J7FYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3" } ] }, { "name": "Trak1", "type": "synonym", "evidence": [ { "id": "XP_027271230", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271230" } ] } ], "protein_names": [ { "name": "Trafficking kinesin-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7FYC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3/entry#names_and_taxonomy" } ] }, { "name": "trafficking kinesin-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027271230", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271230" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271230", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271230" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Trak1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYC3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100772728", "url": "https://www.ncbi.nlm.nih.gov/gene/100772728", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772728", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772728", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FYC3", "url": "https://www.orthodb.org/?gene=A0A9J7FYC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15751:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15751:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12448", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12448", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271230", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271230", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FYC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXR0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K8B1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K8B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8B1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLPDHVRFSPRLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTVPNTASRRYHSLGLFPMDSLAAEIEGTMRKELQLEEPESPDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMTSLLSSCASTPRSSFYGSDVGNMVLDNKTNSILLETEAADLGNEERNKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLRELAEKGELHSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLTGLATSTPVQHPETSGERSRARVTVSGSRSYSSQPQASPEEMHKPPAPAGLEEEEEEGSAHYPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPAPACGSTSHLKSTPVATPCTPRRLSLAESFTNIRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPRMAVIPSTPPNSPMQTPVASPPSFEFKCTSPPYNNFLASKPASSILREVREKKPMRSSESQTDVSVSNLNLVDKVRRFGVARVVNSGRPHIPTLTEDQGPLLCGATGPAQALVPGGLVAEGLPLGCPSGIRRNRSFPTMVGSSVQMRAPVILTSGILMGAKLPKQTSLR", "length": 892, "header": "tr|A0A9J7FYC3-1|A0A9J7FYC3_CRIGR Isoform 1 of Trafficking kinesin-binding protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Trak1 PE=3 SV=1 CANONICAL=A0A9J7FYC3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3/entry#A0A9J7FYC3-1", "sequence": { "sequence": "MTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLPDHVRFSPRLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTVPNTASRRYHSLGLFPMDSLAAEIEGTMRKELQLEEPESPDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMTSLLSSCASTPRSSFYGSDVGNMVLDNKTNSILLETEAADLGNEERNKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLRELAEKGELHSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLTGLATSTPVQHPETSGERSRARVTVSGSRSYSSQPQASPEEMHKPPAPAGLEEEEEEGSAHYPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPAPACGSTSHLKSTPVATPCTPRRLSLAESFTNIRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPRMAVIPSTPPNSPMQTPVASPPSFEFKCTSPPYNNFLASKPASSILREVREKKPMRSSESQTDVSVSNLNLVDKVRRFGVARVVNSGRPHIPTLTEDQGPLLCGATGPAQALVPGGLVAEGLPLGCPSGIRRNRSFPTMVGSSVQMRAPVILTSGILMGAKLPKQTSLR", "length": 892, "header": "tr|A0A9J7FYC3-1|A0A9J7FYC3_CRIGR Isoform 1 of Trafficking kinesin-binding protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Trak1 PE=3 SV=1 CANONICAL=A0A9J7FYC3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3/entry#A0A9J7GXZ8-1", "sequence": { "sequence": "MTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLPDHVRFSPRLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTVPNTASRRYHSLGLFPMDSLAAEIEGTMRKELQLEEPESPDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMTSLLSSCASTPRSSFYGSDVGNMVLDNKTNSILLETEAADLGNEERNKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLRELAEKGELHSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLTGLATSTPVQHPETSAHYPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPAPACGSTSHLKSTPVATPCTPRRLSLAESFTNIRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPRMAVIPSTPPNSPMQTPVASPPSFEFKCTSPPYNNFLASKPASSILREVREKKPMRSSESQTDVSVSNLNLVDKVRRFGVARVVNSGRPHIPTLTEDQGPLLCGATGPAQALVPGGLVAEGLPLGCPSGIRRNRSFPTMVGSSVQMRAPVILTSGILMGAKLPKQTSLR", "length": 848, "header": "tr|A0A9J7GXZ8-1|A0A9J7GXZ8_CRIGR Computationally mapped isoform of Trafficking kinesin-binding protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Trak1 PE=3 SV=1 CANONICAL=A0A9J7FYC3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3/entry#A0A9J7JHZ8-1", "sequence": { "sequence": "MTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTVPNTASRRYHSLGLFPMDSLAAEIEGTMRKELQLEEPESPDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMTSLLSSCASTPRSSFYGSDVGNMVLDNKTNSILLETEAADLGNEERNKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLRELAEKGELHSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLTGLATSTPVQHPETSGERSRARVTVSGSRSYSSQPQASPEEMHKPPAPAGLEEEEEEGSAHYPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPAPACGSTSHLKSTPVATPCTPRRLSLAESFTNIRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPRMAVIPSTPPNSPMQTPVASPPSFEFKCTSPPYNNFLASKPASSILREVREKKPMRSSESQTDVSVSNLNLVDKVRRFGVARVVNSGRPHIPTLTEDQGPLLCGATGPAQALVPGGLVAEGLPLGCPSGIRRNRSFPTMVGSSVQMRAPVILTSGILMGAKLPKQTSLR", "length": 882, "header": "tr|A0A9J7JHZ8-1|A0A9J7JHZ8_CRIGR Computationally mapped isoform of Trafficking kinesin-binding protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Trak1 PE=3 SV=1 CANONICAL=A0A9J7FYC3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3/entry#A0A9J7JQP2-1", "sequence": { "sequence": "MTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTVPNTASRRYHSLGLFPMDSLAAEIEGTMRKELQLEEPESPDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMTSLLSSCASTPRSSFYGSDVGNMVLDNKTNSILLETEAADLGNEERNKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLRELAEKGELHSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLTGLATSTPVQHPETSAHYPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPAPACGSTSHLKSTPVATPCTPRRLSLAESFTNIRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPRMAVIPSTPPNSPMQTPVASPPSFEFKCTSPPYNNFLASKPASSILREVREKKPMRSSESQTDVSVSNLNLVDKVRRFGVARVVNSGRPHIPTLTEDQGPLLCGATGPAQALVPGGLVAEGLPLGCPSGIRRNRSFPTMVGSSVQMRAPVILTSGILMGAKLPKQTSLR", "length": 838, "header": "tr|A0A9J7JQP2-1|A0A9J7JQP2_CRIGR Computationally mapped isoform of Trafficking kinesin-binding protein 1 isoform X5 OS=Cricetulus griseus OX=10029 GN=Trak1 PE=3 SV=1 CANONICAL=A0A9J7FYC3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3/entry#A0A9J7JXR0-1", "sequence": { "sequence": "MTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLPDHVRFSPRLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTVPNTASRRYHSLGLFPMDSLAAEIEGTMRKELQLEEPESPDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMTSLLSSCASTPRSSFYGSDVGNMVLDNKTNSILLETEAADLGNEERNKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLRELAEKGELHSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTAHYPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPAPACGSTSHLKSTPVATPCTPRRLSLAESFTNIRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPRMAVIPSTPPNSPMQTPVASPPSFEFKCTSPPYNNFLASKPASSILREVREKKPMRSSESQTDVSVSNLNLVDKVRRFGVARVVNSGRPHIPTLTEDQGPLLCGATGPAQALVPGGLVAEGLPLGCPSGIRRNRSFPTMVGSSVQMRAPVILTSGILMGAKLPKQTSLR", "length": 827, "header": "tr|A0A9J7JXR0-1|A0A9J7JXR0_CRIGR Computationally mapped isoform of Trafficking kinesin-binding protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Trak1 PE=3 SV=1 CANONICAL=A0A9J7FYC3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K8B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYC3/entry#A0A9J7K8B1-1", "sequence": { "sequence": 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Classification" ] }, { "id": "IPR003645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756574", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FYF2", "url": "https://www.orthodb.org/?gene=A0A9J7FYF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46160:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46160:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272075", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FYF2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPVWTLMLLVGTAWGQHQVSAPMRRQNSLERKPIKMALTSQESSILSKCDFEDDTRPFCDWSQMSSDDGDWIRTTGPSSTGTSGPPGGYPNGEGYYLHMDASTFPRGGVARLRSPDIWEQGPLCIHFAFHMFGLSWGAQLRLLLLRGRNHRRPNILWKHINTQSLSWMPTTVNVPANRDIPSWLMFEGMRGNTAYLDISLDGLSIQRGTCNRICLSQLCTFDILNDLCGWSWVPTATGAKWTQKTGPSEKPGVGPDDDFSSPGRGYYMLLDSTNARSGQKAVLLSPLSHSSGCLTLSFYYIMRGQSVGEGLFVYATFLGNIRKHTLFSGHYGPTWQAVSVNYTGQGQLQFMVVGVFGDKPEPAIAVDAISIAPCGERFPQCNFEDRLHPFCDWSNVLGDSGHWRWGSKSVPTPISGPPREFPYGGEHYIYFDSVNLPQAGQSAKLVSPPFCAPGDVCVEFAYHMYGLGEGTTLKLLLGSPAGSAPISLWNRVGSQSTGWVNSSVTIPKGHQQPMQLFLEATRGSSTAFVVAVNFILISHGPCRGKMELKGPASSPPQYKPSGSYLPALPQIEIYSTSVPIVVPFTPTEENTISTERTTIPPEEITTSTEMITAPTEETTEETTIPTEVTIGSPEETTTPTEVIITPVSPEETSIPLETTSSTEATTVSIEETTSSTEVTTVSPEETTTPTEVTTVSTEVNAASTEVASASTEVTTVSPEETTIPTEMTTVSTEVTGVSTEVASATTEVTTVSPEETTIPTEVITVPPEETTIPIELTTVPPEETTIPIEVTTVHPEETTIPIEVTTVHPEEATFPVEVTTVSPEETTIPIEVTTVPPEETTIPVEVTTVHPEEATFPVEVTTVHPEETTIPIEVTTVHPEEATFPIEVTTVPPEETTFPIEVTTVPPEETTFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEAIFPIEVTTVHPEEAIFPIEVTTVPPEETTFPIEVTTVPPEETTFPIEVTTVPPEETTIPIELTTVHPEETTFPIELTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEETTIPIEVTTVPPEETTIPIEVTTVHPEETTFPIETSGPPEVTSIFSEGAIVSMEETTVFAEHSTFFMQTSTICSPPCPSPSQVPGVSMIGLVPAIGISTTAMRCPPYAHFESCACLASCENPKPSCQSPCSPGCVCNPGFLFSNNQCINESFCNCFYSNKYYQPGEEWFSPNCTERCRCLLGSRLECQISQCGTHTVCQLNNGQYECQPYGTATCLVYGDLHFVTFDERQISFTGTCTYILTQICDNSTDPFFKITASAQERGVEGVASLDKVFITLPETTITLIRGRHTLIGDQSVTLPAIPSNGIFVGLSGRFVELRTAFGLRVRWDGDQQLFVTVSSTYSKKLCGFCGNYDGDGSNDNRKPDGIMTEDEDELGNSWKIEEDKDLADCLGWVFSRCQNKKSTPSCDSALGRIMSGTKLCGQLVDPRGPFETCLFHMKASSFLDNCVMDMCSFQGLQQMLCVHMSAMTATCQDAGYAVGPWRGPQFCPLVCPQNSRYSLCAKPCPDTCHPGSALQPCQEQCVEACECDPGFILSGFECVPQSKCGCTNVEGRYFEIQEQWFNPDCKEICTCEGNNNIRCRPWKCKAQEACIHKNGILGCHAQGAATCIASGDPHYLTFDGALHNFMGTCTYVLTRPCWSNIQENNFVVSVTNEIRDGNLEVSNVKAVHVQVFDLKISLFKGRRVVLNNQRVTLPVWPLKGRVTIRSSGIFVLLYTNFGLQVRYDGNHLVEVTVPSSYTGSLCGLCGNYNNNSLDDNLRPDRKPAGSSLLLGASWKILEASEPGCFVVRGKSSSCEENNMDDTWTKRCAILMNPIGPFSNCHEAVPPQASFSSCVYAQCGTKGDTLALCRSLQAYATLCAQAGQVTTWRNSTFCPLRCQPGSSYNPCANPCPATCLTLSTPKDCPALPCVEGCECQKGYILSGTTCVPLRHCGCSDQGGSYHLLGESWYTERTCTTLCTCSIHSNVTCSPTACEANHVCLRQDGLLRCAAEMGECHISEDSQIVSFDGHIHPIQDMCTYVLVKVCHPNMNLPFFTISAKTDKDTLSKTRTFSVYQIYIDIFSFRVTLQKKHTVLVSWINDTQVTLPATTQIPGISITTEDVYTIVTIKDEVQVKFESNSFLDIKIPASSNGKVCGVCGNFNGEEEDELMTSNEELAQDEQEFMDSWKDKDIDPNCQKIEEQNIQVEQQEIMNGKCRPDDFEKAQANCEAALQGPAWAQCASRVPLKPFLLGCMNNFCEFRELFRALCEALQSFEDACQNQGLKPPIWRNSSFCPLECPAHSHYTNCLPSCPPSCLDPDSRCEGSGHKVPATCKEGCICQPGYVLNNDKCVLKTHCGCKDAQGVFVPAGKTWMSTGCTQTCACTRGAIRCRNFQCPLGTHCKDNNDGSSNCVKIIFQCPAHSQYTDCLPSCHPSCSDPEGHCEGISTKAPATCKEGCVCQPGYVLRKDKCVLKIECGCQDTQGGFIPAGKTWISRGCTQSCTCMGGAIQCRNFQCPPGTYCKDSDDGNSNCAKITLQCPAHSQYTNCLPSCLPSCLDLEGHCGGISTKAPATCKEGCVCQPGYVLNNDKCMLKIECDCQDTQGVFIPVSKTWTSRGCTQSCTCVGGVIQCRNFQCPPGTYCKDTNDGNSNCTKITLQCPAHTLYTNCLPSCLPSCSDPDGLCMGTSPKAPSSCKEGCVCRSGFVLHNDKCMLRIRCGCKDTQGVLIPANKTWINRGCTQSCTCSGGAILCRKFQCPPETYCKDIEDGNSNCTKITLQCPAHSQYTDCLPSCQPSCSDPDGRCVGSGTKGPSTCKEGCACQPGYVLDNDKCMLRIQCGCKDAQGVLIPADKTWINRGCTQSCICMGGVIQCQKFHCPSETYCKNTEDGNSNCAKITLQCPVHSHYTNCLPSCPPTCSDPEGHCEDVSTKAPSTCKEGCVCQPNHVLHNHQCMLRTECGCKDAQGVLIPADKTWINRGCTQSCTCSGGAILCRKFQCPPETYCKNIEDGNSNCTKITLQCPANSHFTDCLPSCQPSCSNVKGHCEDSSPKAPSTCKEGCICQPGYVLQKDQCILRTECGCKDAQGALIPEGKTWITRGCTQSCTCIEGVIQCRTFQCPLGTYCKSSDDVNSSCVKITLQCPAHSRYSNCLPFCPPTCLDPEGLCGSTSPKAPSTCKEGCVCRPGFVLHNDKCMLRILCDCKDAQGTLIPADKTWITRGCTQSCTCVAGVIHCKNIQCPPGTYCKNRDDGSTNCTKITLQCPTHSQFTDCLPSCLPSCSNHCEITSPKGPSNCKEGCLCDHGFVLNENKCVPRTECGCKDARGTFIPAGKTWTSKGCTQSCACTEGNIQCQNFHCPSETYCKDNSDDSSTCVKITLQCPAHTHFTSCLPSCLPSCSDPGGLCKGTSPKAPATCKEGCICQPDHVLHNDKCILRIQCDCKDAHGALIPAGKTWISTGCTQSCACMEGAVQCQDFKCPSGTYCKNNNEGSSNCAKITLQCPDHSLFTDCLPSCLPSCLDPEGLCKETSPKAPSTCKEGCVCEPGLVLQKDTCVLKTECGCKDAHGALIPVSKTWVSRGCTQSCTCTGGIIQCQSFQCPPETYCKNSNDDSSNCVKIPLQCPANSQYTDCLPRCPPTCLDPEGHCEGTGPTGPSTCKEGCVCQPGYVIDKDKCVLRMQCDCKDAHGVLIPAGKTWTPRGCNQSCTCMAGAVQCRNFQCPSGTYCKDSNDGSSNCARIPLQCPAHSLYTDCLPSCQPSCLDPDAHCEGITPKAPSTCKEGCSCQPGYVLANDKCVLKIECGCKGTQGGFIPAGKTWIATGCSQSCTCVGGTIECRNFLCPSGTYCKDRDDGSSNCAKITLQCPDHSHFTSCLPSCPPSCLNLDGRCEGTSPQVPSTCKEGCLCQPGYFLNKNKCVLQIHCDCQDARGDLIPAGKTWTSRGCTQNCACAGGAIQCQNFQCPSGTYCKDSSDGNSNCAKISKGVMGEGGRGVLMAGGIRALQCPAHSQFTSCLPSCPPSCAILDGHCEEASSKVPTTCKEGCICRPGYLLNNDKCVLRIQCSCNDGHGGLIPAGKTWINEDCTETCNCMGGTIQCRNFQCPPGTYCKNNNDDSRNCAKITLQCPAHSRYTNCLPPCLPSCANLDGLCGVTISKVSSTCKEGCICQPGYVLNNNKCVLQIHCGCKNAQGDLIPAGKTWTSRGCTQSCTCVGGAVQCHNFNCPSGTQCQDDQDGNSSCAKITLQCPTHSRYTNCLPSCLPSCADPEGLCGGTSPKAPSTCKEGCVCRAGFVLHNNKCVLRIQCACKDAHGVLIPVNKTWISKGCTQNCTCLAGNIRCRDFHCPSGTRCKDNGDGSSNCAKVVLECPDNSHHTNCLPSCIPSCSNLNEHCEVEGLRAPSICKEGCLCQPGFVLNKDKCIPRIQCGCKDSQGTPILAGKTWISTGCSQKCTCVEGLVHCHDFKCPAGTQCQDIEEGSSNCVENTFQCPAHSRFTNCLPSCLPSCLDPDAHCKGTSPKDPAVCKAGCLCQSGYVLSNDKCILRIQCGCKDAQGALIPEGKTWISRGCIQSCACKGGAVQCRDFKCPAESHCQLYEDGSSSCVTSALKCPAHSFYTNCLPSCLPSCLDPEGLCKGSSPKAPSTCKEGCVCRSGYVLQNNKCMLRIHCACKLSQGNLIQTGQSWISSDCTQICACKGGLFQCQSFQCPSGTQCKVYEDGSSNCVSKTLQCPAHSLYTDCLPSCLPSCSNPNGLCEGISTKAPSTCKEGCVCRPGFLFSDNKCVLKDQCGCKDAQGDSIPAGKTWISSGCTQSCTCVAGAVQCRNFVCPTGSHCQHSDDGSSNCAVNKLEKCTAFGDPYYHTFDGFDYRFPGRMNYYLIKTVDKLPEGIEPLVTEGRNKISSKGSPALHEVTTIVYGYKIQLQKGLVVLVNDQKVAIPYSPNHHLRVILRAQRLFLITDFEMVVDFDGKQTAVISLPTVYRGLIRGLCGNYDKNQANDFMLPNGMLTSNINAFGNSWEVKVVEVLFRSPRALPDDGGGEEPELLRSECSPEQTALTSSTQACRVLMDPQGPFAACHQIVSPEPFEQHCMSDMCSSWKTKDEEELRCRVLSGYAILCQEAGVNMTGWRDQTHCAMTCPANTVYQSCMTPCPASCAKFVTPKVCDGPCVEGCAAIPGYIYSDTQSLPVTHCGCSTNGTYYKLGDSFVTDDCSQHCTCASQGILQCEPYGCRAGESCTVANFTRGCFRDSPCLQNPCHNDGRCQEQGATFICHCDLGYGGKFCTEPQDIPSRKKLESSSLMAILPGVLVMVLVPVLLPRVYVYMATRTTTARRRRRGEKLLRRNRHSLEDTDVPEPSFKATEF", "length": 5457, "header": "tr|A0A9J7FYF2-1|A0A9J7FYF2_CRIGR Isoform 1 of Zonadhesin OS=Cricetulus griseus OX=10029 GN=Zan PE=4 SV=1 CANONICAL=A0A9J7FYF2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF2/entry#A0A9J7FYF2-1", "sequence": { "sequence": "MAPPVWTLMLLVGTAWGQHQVSAPMRRQNSLERKPIKMALTSQESSILSKCDFEDDTRPFCDWSQMSSDDGDWIRTTGPSSTGTSGPPGGYPNGEGYYLHMDASTFPRGGVARLRSPDIWEQGPLCIHFAFHMFGLSWGAQLRLLLLRGRNHRRPNILWKHINTQSLSWMPTTVNVPANRDIPSWLMFEGMRGNTAYLDISLDGLSIQRGTCNRICLSQLCTFDILNDLCGWSWVPTATGAKWTQKTGPSEKPGVGPDDDFSSPGRGYYMLLDSTNARSGQKAVLLSPLSHSSGCLTLSFYYIMRGQSVGEGLFVYATFLGNIRKHTLFSGHYGPTWQAVSVNYTGQGQLQFMVVGVFGDKPEPAIAVDAISIAPCGERFPQCNFEDRLHPFCDWSNVLGDSGHWRWGSKSVPTPISGPPREFPYGGEHYIYFDSVNLPQAGQSAKLVSPPFCAPGDVCVEFAYHMYGLGEGTTLKLLLGSPAGSAPISLWNRVGSQSTGWVNSSVTIPKGHQQPMQLFLEATRGSSTAFVVAVNFILISHGPCRGKMELKGPASSPPQYKPSGSYLPALPQIEIYSTSVPIVVPFTPTEENTISTERTTIPPEEITTSTEMITAPTEETTEETTIPTEVTIGSPEETTTPTEVIITPVSPEETSIPLETTSSTEATTVSIEETTSSTEVTTVSPEETTTPTEVTTVSTEVNAASTEVASASTEVTTVSPEETTIPTEMTTVSTEVTGVSTEVASATTEVTTVSPEETTIPTEVITVPPEETTIPIELTTVPPEETTIPIEVTTVHPEETTIPIEVTTVHPEEATFPVEVTTVSPEETTIPIEVTTVPPEETTIPVEVTTVHPEEATFPVEVTTVHPEETTIPIEVTTVHPEEATFPIEVTTVPPEETTFPIEVTTVPPEETTFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEAIFPIEVTTVHPEEAIFPIEVTTVPPEETTFPIEVTTVPPEETTFPIEVTTVPPEETTIPIELTTVHPEETTFPIELTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEEATFPIEVTTVHPEETTIPIEVTTVPPEETTIPIEVTTVHPEETTFPIETSGPPEVTSIFSEGAIVSMEETTVFAEHSTFFMQTSTICSPPCPSPSQVPGVSMIGLVPAIGISTTAMRCPPYAHFESCACLASCENPKPSCQSPCSPGCVCNPGFLFSNNQCINESFCNCFYSNKYYQPGEEWFSPNCTERCRCLLGSRLECQISQCGTHTVCQLNNGQYECQPYGTATCLVYGDLHFVTFDERQISFTGTCTYILTQICDNSTDPFFKITASAQERGVEGVASLDKVFITLPETTITLIRGRHTLIGDQSVTLPAIPSNGIFVGLSGRFVELRTAFGLRVRWDGDQQLFVTVSSTYSKKLCGFCGNYDGDGSNDNRKPDGIMTEDEDELGNSWKIEEDKDLADCLGWVFSRCQNKKSTPSCDSALGRIMSGTKLCGQLVDPRGPFETCLFHMKASSFLDNCVMDMCSFQGLQQMLCVHMSAMTATCQDAGYAVGPWRGPQFCPLVCPQNSRYSLCAKPCPDTCHPGSALQPCQEQCVEACECDPGFILSGFECVPQSKCGCTNVEGRYFEIQEQWFNPDCKEICTCEGNNNIRCRPWKCKAQEACIHKNGILGCHAQGAATCIASGDPHYLTFDGALHNFMGTCTYVLTRPCWSNIQENNFVVSVTNEIRDGNLEVSNVKAVHVQVFDLKISLFKGRRVVLNNQRVTLPVWPLKGRVTIRSSGIFVLLYTNFGLQVRYDGNHLVEVTVPSSYTGSLCGLCGNYNNNSLDDNLRPDRKPAGSSLLLGASWKILEASEPGCFVVRGKSSSCEENNMDDTWTKRCAILMNPIGPFSNCHEAVPPQASFSSCVYAQCGTKGDTLALCRSLQAYATLCAQAGQVTTWRNSTFCPLRCQPGSSYNPCANPCPATCLTLSTPKDCPALPCVEGCECQKGYILSGTTCVPLRHCGCSDQGGSYHLLGESWYTERTCTTLCTCSIHSNVTCSPTACEANHVCLRQDGLLRCAAEMGECHISEDSQIVSFDGHIHPIQDMCTYVLVKVCHPNMNLPFFTISAKTDKDTLSKTRTFSVYQIYIDIFSFRVTLQKKHTVLVSWINDTQVTLPATTQIPGISITTEDVYTIVTIKDEVQVKFESNSFLDIKIPASSNGKVCGVCGNFNGEEEDELMTSNEELAQDEQEFMDSWKDKDIDPNCQKIEEQNIQVEQQEIMNGKCRPDDFEKAQANCEAALQGPAWAQCASRVPLKPFLLGCMNNFCEFRELFRALCEALQSFEDACQNQGLKPPIWRNSSFCPLECPAHSHYTNCLPSCPPSCLDPDSRCEGSGHKVPATCKEGCICQPGYVLNNDKCVLKTHCGCKDAQGVFVPAGKTWMSTGCTQTCACTRGAIRCRNFQCPLGTHCKDNNDGSSNCVKIIFQCPAHSQYTDCLPSCHPSCSDPEGHCEGISTKAPATCKEGCVCQPGYVLRKDKCVLKIECGCQDTQGGFIPAGKTWISRGCTQSCTCMGGAIQCRNFQCPPGTYCKDSDDGNSNCAKITLQCPAHSQYTNCLPSCLPSCLDLEGHCGGISTKAPATCKEGCVCQPGYVLNNDKCMLKIECDCQDTQGVFIPVSKTWTSRGCTQSCTCVGGVIQCRNFQCPPGTYCKDTNDGNSNCTKITLQCPAHTLYTNCLPSCLPSCSDPDGLCMGTSPKAPSSCKEGCVCRSGFVLHNDKCMLRIRCGCKDTQGVLIPANKTWINRGCTQSCTCSGGAILCRKFQCPPETYCKDIEDGNSNCTKITLQCPAHSQYTDCLPSCQPSCSDPDGRCVGSGTKGPSTCKEGCACQPGYVLDNDKCMLRIQCGCKDAQGVLIPADKTWINRGCTQSCICMGGVIQCQKFHCPSETYCKNTEDGNSNCAKITLQCPVHSHYTNCLPSCPPTCSDPEGHCEDVSTKAPSTCKEGCVCQPNHVLHNHQCMLRTECGCKDAQGVLIPADKTWINRGCTQSCTCSGGAILCRKFQCPPETYCKNIEDGNSNCTKITLQCPANSHFTDCLPSCQPSCSNVKGHCEDSSPKAPSTCKEGCICQPGYVLQKDQCILRTECGCKDAQGALIPEGKTWITRGCTQSCTCIEGVIQCRTFQCPLGTYCKSSDDVNSSCVKITLQCPAHSRYSNCLPFCPPTCLDPEGLCGSTSPKAPSTCKEGCVCRPGFVLHNDKCMLRILCDCKDAQGTLIPADKTWITRGCTQSCTCVAGVIHCKNIQCPPGTYCKNRDDGSTNCTKITLQCPTHSQFTDCLPSCLPSCSNHCEITSPKGPSNCKEGCLCDHGFVLNENKCVPRTECGCKDARGTFIPAGKTWTSKGCTQSCACTEGNIQCQNFHCPSETYCKDNSDDSSTCVKITLQCPAHTHFTSCLPSCLPSCSDPGGLCKGTSPKAPATCKEGCICQPDHVLHNDKCILRIQCDCKDAHGALIPAGKTWISTGCTQSCACMEGAVQCQDFKCPSGTYCKNNNEGSSNCAKITLQCPDHSLFTDCLPSCLPSCLDPEGLCKETSPKAPSTCKEGCVCEPGLVLQKDTCVLKTECGCKDAHGALIPVSKTWVSRGCTQSCTCTGGIIQCQSFQCPPETYCKNSNDDSSNCVKIPLQCPANSQYTDCLPRCPPTCLDPEGHCEGTGPTGPSTCKEGCVCQPGYVIDKDKCVLRMQCDCKDAHGVLIPAGKTWTPRGCNQSCTCMAGAVQCRNFQCPSGTYCKDSNDGSSNCARIPLQCPAHSLYTDCLPSCQPSCLDPDAHCEGITPKAPSTCKEGCSCQPGYVLANDKCVLKIECGCKGTQGGFIPAGKTWIATGCSQSCTCVGGTIECRNFLCPSGTYCKDRDDGSSNCAKITLQCPDHSHFTSCLPSCPPSCLNLDGRCEGTSPQVPSTCKEGCLCQPGYFLNKNKCVLQIHCDCQDARGDLIPAGKTWTSRGCTQNCACAGGAIQCQNFQCPSGTYCKDSSDGNSNCAKISKGVMGEGGRGVLMAGGIRALQCPAHSQFTSCLPSCPPSCAILDGHCEEASSKVPTTCKEGCICRPGYLLNNDKCVLRIQCSCNDGHGGLIPAGKTWINEDCTETCNCMGGTIQCRNFQCPPGTYCKNNNDDSRNCAKITLQCPAHSRYTNCLPPCLPSCANLDGLCGVTISKVSSTCKEGCICQPGYVLNNNKCVLQIHCGCKNAQGDLIPAGKTWTSRGCTQSCTCVGGAVQCHNFNCPSGTQCQDDQDGNSSCAKITLQCPTHSRYTNCLPSCLPSCADPEGLCGGTSPKAPSTCKEGCVCRAGFVLHNNKCVLRIQCACKDAHGVLIPVNKTWISKGCTQNCTCLAGNIRCRDFHCPSGTRCKDNGDGSSNCAKVVLECPDNSHHTNCLPSCIPSCSNLNEHCEVEGLRAPSICKEGCLCQPGFVLNKDKCIPRIQCGCKDSQGTPILAGKTWISTGCSQKCTCVEGLVHCHDFKCPAGTQCQDIEEGSSNCVENTFQCPAHSRFTNCLPSCLPSCLDPDAHCKGTSPKDPAVCKAGCLCQSGYVLSNDKCILRIQCGCKDAQGALIPEGKTWISRGCIQSCACKGGAVQCRDFKCPAESHCQLYEDGSSSCVTSALKCPAHSFYTNCLPSCLPSCLDPEGLCKGSSPKAPSTCKEGCVCRSGYVLQNNKCMLRIHCACKLSQGNLIQTGQSWISSDCTQICACKGGLFQCQSFQCPSGTQCKVYEDGSSNCVSKTLQCPAHSLYTDCLPSCLPSCSNPNGLCEGISTKAPSTCKEGCVCRPGFLFSDNKCVLKDQCGCKDAQGDSIPAGKTWISSGCTQSCTCVAGAVQCRNFVCPTGSHCQHSDDGSSNCAVNKLEKCTAFGDPYYHTFDGFDYRFPGRMNYYLIKTVDKLPEGIEPLVTEGRNKISSKGSPALHEVTTIVYGYKIQLQKGLVVLVNDQKVAIPYSPNHHLRVILRAQRLFLITDFEMVVDFDGKQTAVISLPTVYRGLIRGLCGNYDKNQANDFMLPNGMLTSNINAFGNSWEVKVVEVLFRSPRALPDDGGGEEPELLRSECSPEQTALTSSTQACRVLMDPQGPFAACHQIVSPEPFEQHCMSDMCSSWKTKDEEELRCRVLSGYAILCQEAGVNMTGWRDQTHCAMTCPANTVYQSCMTPCPASCAKFVTPKVCDGPCVEGCAAIPGYIYSDTQSLPVTHCGCSTNGTYYKLGDSFVTDDCSQHCTCASQGILQCEPYGCRAGESCTVANFTRGCFRDSPCLQNPCHNDGRCQEQGATFICHCDLGYGGKFCTEPQDIPSRKKLESSSLMAILPGVLVMVLVPVLLPRVYVYMATRTTTARRRRRGEKLLRRNRHSLEDTDVPEPSFKATEF", "length": 5457, "header": "tr|A0A9J7FYF2-1|A0A9J7FYF2_CRIGR Isoform 1 of Zonadhesin OS=Cricetulus griseus OX=10029 GN=Zan PE=4 SV=1 CANONICAL=A0A9J7FYF2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3759, "start_aa": "Thr", "end_pos": 3759, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3759", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"monoisotopic_mass": 28809.0 }, "refseq": { "ac": "XP_007626349", "name": "diablo homolog, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007626349" }, "gene_names": [ { "name": "Diablo", "type": "recommended", "evidence": [ { "id": "A0A9J7FYF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8" } ] }, { "name": "Diablo", "type": "synonym", "evidence": [ { "id": "XP_007626349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007626349" } ] } ], "protein_names": [ { "name": "Diablo IAP-binding mitochondrial protein", "type": "recommended", "evidence": [ { "id": "A0A9J7FYF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8/entry#names_and_taxonomy" } ] }, { "name": "Diablo homolog, mitochondrial", "type": "synonym", "evidence": [ { "id": "A0A9J7FYF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8/entry#names_and_taxonomy" } ] }, { "name": "Direct IAP-binding protein with low pI", "type": "synonym", "evidence": [ { "id": "A0A9J7FYF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8/entry#names_and_taxonomy" } ] }, { "name": "diablo homolog, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007626349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007626349" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 212 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613692.1) and transcript sequence (IACG01091328.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007626349.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007626349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007626349" } ] }, { "annotation": "Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/BRUCE by inhibiting its binding to caspases.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8#function" }, { "database": "UniProtKB", "id": "ARBA00057426", "url": "https://www.uniprot.org/uniprotkb/ARBA00057426#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Diablo", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYF8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYF8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100754770", "url": "https://www.ncbi.nlm.nih.gov/gene/100754770", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015142", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754770", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754770", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FYF8", "url": "https://www.orthodb.org/?gene=A0A9J7FYF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32247:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32247:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007626349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007626349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FYF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRHFRRVRPASVRRGMAALRSWMSRSVASLFRYGQRVPVVANSKKRCFSALIRPWHKTMMAGFGMTLCAVPIAQKSEPQSLSNEALMRRAVSLVTDSTSTFLSQTTYALMEAITEYTKAVYTLVSLYRQYTSLLGKMNSQEEDEVWQVIIGARVEMTSKQQEYMKLETTWMTAVSLSEMAAEAAYQTGADQASITARNHIQLVKSQVQEVRQLSQKAETKLAETQTQELHQKMQEAGEERADQEEDAYLRED", "length": 253, "header": "tr|A0A9J7FYF8-1|A0A9J7FYF8_CRIGR Isoform 1 of Diablo IAP-binding mitochondrial protein OS=Cricetulus griseus OX=10029 GN=Diablo PE=3 SV=1 CANONICAL=A0A9J7FYF8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8/entry#A0A9J7FYF8-1", "sequence": { "sequence": "MLRHFRRVRPASVRRGMAALRSWMSRSVASLFRYGQRVPVVANSKKRCFSALIRPWHKTMMAGFGMTLCAVPIAQKSEPQSLSNEALMRRAVSLVTDSTSTFLSQTTYALMEAITEYTKAVYTLVSLYRQYTSLLGKMNSQEEDEVWQVIIGARVEMTSKQQEYMKLETTWMTAVSLSEMAAEAAYQTGADQASITARNHIQLVKSQVQEVRQLSQKAETKLAETQTQELHQKMQEAGEERADQEEDAYLRED", "length": 253, "header": "tr|A0A9J7FYF8-1|A0A9J7FYF8_CRIGR Isoform 1 of Diablo IAP-binding mitochondrial protein OS=Cricetulus griseus OX=10029 GN=Diablo PE=3 SV=1 CANONICAL=A0A9J7FYF8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754770", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754770", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8" } ], "pmid": "" }, { "name": "neuron apoptotic process", "id": "GO:0051402", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051402", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway in response to oxidative stress", "id": "GO:0008631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008631", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FYF9-1", "uniprot_ac": "A0A9J7FYF9", "uniprot_id": "A0A9J7FYF9_CRIGR", "mass": { "chemical_mass": 28000.0, "monoisotopic_mass": 28000.0 }, "refseq": { "ac": "XP_027271414", "name": "ATP synthase subunit O, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271414" }, "gene_names": [ { "name": "Atp5po", "type": "recommended", "evidence": [ { "id": "A0A9J7FYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9" } ] }, { "name": "Atp5po", "type": "synonym", "evidence": [ { "id": "XP_027271414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271414" } ] } ], "protein_names": [ { "name": "ATP synthase peripheral stalk subunit OSCP, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A9J7FYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase subunit O, mitochondrial isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027271414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271414" } ] }, { "name": "ATP synthase subunit O", "type": "synonym", "evidence": [ { "id": "A0A9J7FYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9/entry#names_and_taxonomy" } ] }, { "name": "Oligomycin sensitivity conferral protein", "type": "synonym", "evidence": [ { "id": "A0A9J7FYF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271414" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Atp5po", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100770018", "url": "https://www.ncbi.nlm.nih.gov/gene/100770018", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770018", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770018", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FYF9", "url": "https://www.orthodb.org/?gene=A0A9J7FYF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11910", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11910", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00213", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271414", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FYF9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEVSTHAPWHPGSPFPRELSGHAGARVRSGTCGRRLGVTYLRRGKMAACGLSRQVRSFSTSVVRPFAKLVRPPVQIYGIEGRYATALYSAAVKQNKLDQVEKELLRVGQLLKDPKVSLAVLNPYVKRSIKVKSLSDITAKEKLSPLTANLMNLLAENGRLDNTHGIISAFSTIMSVHRGEVPCMVTTASALNEAVLSELKTVLKSFLGKGQVLNLKVKTDPSIMGGMIVQIGEKYVDMSTKTKIQKLSKAMRDLL", "length": 256, "header": "tr|A0A9J7FYF9-1|A0A9J7FYF9_CRIGR Isoform 1 of ATP synthase peripheral stalk subunit OSCP, mitochondrial OS=Cricetulus griseus OX=10029 GN=Atp5po PE=3 SV=1 CANONICAL=A0A9J7FYF9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9/entry#A0A9J7FYF9-1", "sequence": { "sequence": "MQEVSTHAPWHPGSPFPRELSGHAGARVRSGTCGRRLGVTYLRRGKMAACGLSRQVRSFSTSVVRPFAKLVRPPVQIYGIEGRYATALYSAAVKQNKLDQVEKELLRVGQLLKDPKVSLAVLNPYVKRSIKVKSLSDITAKEKLSPLTANLMNLLAENGRLDNTHGIISAFSTIMSVHRGEVPCMVTTASALNEAVLSELKTVLKSFLGKGQVLNLKVKTDPSIMGGMIVQIGEKYVDMSTKTKIQKLSKAMRDLL", "length": 256, "header": "tr|A0A9J7FYF9-1|A0A9J7FYF9_CRIGR Isoform 1 of ATP synthase peripheral stalk subunit OSCP, mitochondrial OS=Cricetulus griseus OX=10029 GN=Atp5po PE=3 SV=1 CANONICAL=A0A9J7FYF9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"UniProtKB", "id": "A0A9J7FYF9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton-transporting ATP synthase activity, rotational mechanism", "id": "GO:0046933", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046933", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYF9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { 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This record is derived from a genomic sequence (NW_003614462.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016833927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833927" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dop1b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9", "locus": {} } ], "crossref": [ { "id": "100751759", "url": "https://www.ncbi.nlm.nih.gov/gene/100751759", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007249", "database": "InterPro", "categories": [ "Protein Classification" ] 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"MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLLISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYERYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYDRTDALLLRLSLVVGREVFYAALWGSVLTSPSIRLPASLFVVSHISRDSPGKEQKYMLGADYQLTVKSLCASLLDTNVLVQRNNLEIILFFFPFYTCLDPDERAIPLLRRDVVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPEFVISSSYEDQSSYFFDKYSKNLLVEALSEILHQKFSDADIEERQHAYLKPFRILLSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGSDLKLSYTQSGNLLTSTIKENRHASEIVKTVNLLVSLLSTDFLWDYMARCFEECFRPVTQTAIGEAIGPPPTVAELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLAELTHALKTCFKVLSKVQMPPSYLDMAASSGNSSPVKGESSDIILETKASDEEAPFPPLKSEDSGIGLSASSPELSERLRVPRVSAERDDIWKKDGTMQRTFLCIQELIANFASKNIFAASLTVSGEESKPEEPPGKSDKGISHSGRKSSWDPKPITVPQFKQMLSDLFTARGSPFKTKSSESMSSVPSSPHRKAEAEWDIDEVVIELVGSKEDCREAFAAACHLLLDCATFPVYLSAEETEQLCEMLFQTSEASDCSFPSWLKSLMTICCCVNDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTRETQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIHCLKQENSAEDLHRWFNRKRHTFKEACGISEPQEGTSEEHLPLGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDMPYYMDLPDRIASCGPDSSEHTESADTSSVHTDSENTSTFSSPSHDLQDLSHEENCCAPIPIGGKAYSKRAALLPTLQPESLKSSAKLGLVRADSDKTQASESLSSDEEADVELQAITTTSRLLRQQKEKQESLEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALVGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDVLGNRDVQVKSVEVLIRITTQLVSVAKSSEGKNVEFIHSLLQKCKVQEFVLLSLSASMYTSQKRYGLATADRGRVPMEVSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEDAQSQPALSREWQRALNFQQAIGAMQYVQPHPLPSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDELVKQYESESVKLSVSTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAISDPINLRNAKNAILEELPRIVNTMALIWNVLRKEDTQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTAHLGVQLIAAVATVWSRKQARRHSKTKIVPMASASQHTLVDLVCALSTLQTDSVLQLVKEVVKRPLQIKGDEKSPLVDIPVLQFCYAFIQRLSIPDLQENFPSLLGVLKESVQLNLAPPGYFLLLSILNDFVTRTPNPESKKDQKDLQEITQKILEAIGTIAGSSLEQTSWLSRNLEVRAQPQVSLEESDAEDDEHADTDAAVASAMVSASAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWKKEVLELFLDPAFFQMDTSCAHWKSIIDHLLTHEKTMFKDLMNMQSSSLKLFSSVDQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSTVAAQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFLQLEEDLKEEDESLRNSNKTNRIKVPVADGNGPSGGTVSPGDLIMYLSACKFLDTALSFPPDKMPLFQIYRWAFVPEVDTEHPTFLSELEENHQECRPHTVRILELLRSKYGETGSSDEITRESEFPLLRQHSVSSIRQLIPFFKTLNCAFKTQSHLPSDAPGTSVPELPVVDSPRVLRQLEECVEHDFLEYPEC", "length": 2291, "header": "tr|A0A9J7FYG9-1|A0A9J7FYG9_CRIGR Isoform 1 of Protein dopey-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Dop1b PE=3 SV=1 CANONICAL=A0A9J7FYG9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MH97-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9/entry#A0A8C2MH97-1", "sequence": { "sequence": "MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLLISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYERYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYDRTDALLLRLSLVVGREVFYAALWGSVLTSPSIRLPASLFVVSHISRDSPGKEQKYMLGADYQLTVKSLCASLLDTNVLVQRNNLEIILFFFPFYTCLDPDERAIPLLRRDVVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPEFVISSSYEDQSSYFFDKYSKNLLVEALSEILHQKFSDADIEERQHAYLKPFRILLSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGSDLKLSYTQSGNLLTSTIKENRHASEIVKTVNLLVSLLSTDFLWDYMARCFEECFRPVTQTAIGEAIGPPPTVAELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLAELTHALKTCFKVLSKVQMPPSYLDMAASSGNSSPVKGESSDIILETKASDEEAPFPPLKSEDSGIGLSASSPELSERLRVPRVSAERDDIWKKDGTMQRTFLCIQELIANFASKNIFAASLTVSGEESKPEEPPGKSDKGISHSGRKSSWDPKPITVPQFKQMLSDLFTARGSPFKTKSSESMSSVPSSPHRKAEAEWDIDEVVIELVGSKEDCREAFAAACHLLLDCATFPVYLSAEETEQLCEMLFQTSEASDCSFPSWLKSLMTICCCVNDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTRETQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIHCLKQENSAEDLHRWFNRKRHTFKEACGISEPQEGTSEEHLPLGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDMPYYMDLPDRIASCGPDSSEHTESADTSSVHTDSENTSTFSSPSHDLQDLSHEENCCAPIPIGGKAYSKRAALLPTLQPESLKSSAKLGLVRADSDKTQASESLSSDEEADVELQAITTTSRLLRQQKEKQESLEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALVGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDVLGNRDVQVKSVEVLIRITTQLVSVAKSSEGKNVEFIHSLLQKCKVQEFVLLSLSASMYTSQKRYGLATADRGRVPMEVSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEDAQSQPALSREWQRALNFQQAIGAMQYVQPHPLPSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDELVKQYESESVKLSVSTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAISDPINLRNAKNAILEELPRIVNTMALIWNVLRKEDTQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTAHLGVQLIAAVATVWSRKQARRHSKTKIVPMASASQHTLVDLVCALSTLQTDSVLQLVKEVVKRPLQIKGDEKSPLVDIPVLQFCYAFIQRLSIPDLQENFPSLLGVLKESVQLNLAPPGYFLLLSILNDFVTRTPNPESKKDQKDLQEITQKILEAIGTIAGSSLEQTSWLSRNLEVRAQPQVSLEESDAEDDEHDTDAAVASAMVSASAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWKKEVLELFLDPAFFQMDTSCAHWKSIIDHLLTHEKTMFKDLMNMQSSSLKLFSSVDQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSTVAAQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFLQLEEDLKEEDESLRNSNKTNRIKVPVADGNGPSGGTVSPGDLIMYLSACKFLDTALSFPPDKMPLFQIYRWAFVPEVDTEHPTFLSELEENHQECRPHTVRILELLRSKYGETGSSDEITRESEFPLLRQHSVSSIRQLIPFFKTLNCAFKTQSHLPSDAPGTSVPELPVVDSPRVLRQLEECVEHDFLEYPEC", "length": 2290, "header": "tr|A0A8C2MH97-1|A0A8C2MH97_CRIGR Computationally mapped isoform of Protein dopey-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dop1b PE=3 SV=1 CANONICAL=A0A9J7FYG9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9/entry#A0A9J7FYG9-1", "sequence": { "sequence": "MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLLISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYERYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYDRTDALLLRLSLVVGREVFYAALWGSVLTSPSIRLPASLFVVSHISRDSPGKEQKYMLGADYQLTVKSLCASLLDTNVLVQRNNLEIILFFFPFYTCLDPDERAIPLLRRDVVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPEFVISSSYEDQSSYFFDKYSKNLLVEALSEILHQKFSDADIEERQHAYLKPFRILLSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGSDLKLSYTQSGNLLTSTIKENRHASEIVKTVNLLVSLLSTDFLWDYMARCFEECFRPVTQTAIGEAIGPPPTVAELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLAELTHALKTCFKVLSKVQMPPSYLDMAASSGNSSPVKGESSDIILETKASDEEAPFPPLKSEDSGIGLSASSPELSERLRVPRVSAERDDIWKKDGTMQRTFLCIQELIANFASKNIFAASLTVSGEESKPEEPPGKSDKGISHSGRKSSWDPKPITVPQFKQMLSDLFTARGSPFKTKSSESMSSVPSSPHRKAEAEWDIDEVVIELVGSKEDCREAFAAACHLLLDCATFPVYLSAEETEQLCEMLFQTSEASDCSFPSWLKSLMTICCCVNDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTRETQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIHCLKQENSAEDLHRWFNRKRHTFKEACGISEPQEGTSEEHLPLGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDMPYYMDLPDRIASCGPDSSEHTESADTSSVHTDSENTSTFSSPSHDLQDLSHEENCCAPIPIGGKAYSKRAALLPTLQPESLKSSAKLGLVRADSDKTQASESLSSDEEADVELQAITTTSRLLRQQKEKQESLEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALVGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDVLGNRDVQVKSVEVLIRITTQLVSVAKSSEGKNVEFIHSLLQKCKVQEFVLLSLSASMYTSQKRYGLATADRGRVPMEVSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEDAQSQPALSREWQRALNFQQAIGAMQYVQPHPLPSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDELVKQYESESVKLSVSTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAISDPINLRNAKNAILEELPRIVNTMALIWNVLRKEDTQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTAHLGVQLIAAVATVWSRKQARRHSKTKIVPMASASQHTLVDLVCALSTLQTDSVLQLVKEVVKRPLQIKGDEKSPLVDIPVLQFCYAFIQRLSIPDLQENFPSLLGVLKESVQLNLAPPGYFLLLSILNDFVTRTPNPESKKDQKDLQEITQKILEAIGTIAGSSLEQTSWLSRNLEVRAQPQVSLEESDAEDDEHADTDAAVASAMVSASAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWKKEVLELFLDPAFFQMDTSCAHWKSIIDHLLTHEKTMFKDLMNMQSSSLKLFSSVDQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSTVAAQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFLQLEEDLKEEDESLRNSNKTNRIKVPVADGNGPSGGTVSPGDLIMYLSACKFLDTALSFPPDKMPLFQIYRWAFVPEVDTEHPTFLSELEENHQECRPHTVRILELLRSKYGETGSSDEITRESEFPLLRQHSVSSIRQLIPFFKTLNCAFKTQSHLPSDAPGTSVPELPVVDSPRVLRQLEECVEHDFLEYPEC", "length": 2291, "header": "tr|A0A9J7FYG9-1|A0A9J7FYG9_CRIGR Isoform 1 of Protein dopey-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Dop1b PE=3 SV=1 CANONICAL=A0A9J7FYG9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9/entry#A0A9J7FYM7-1", "sequence": { "sequence": "MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLLISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYERYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYDRTDALLLRLSLVVGREVFYAALWGSVLTSPSIRLPASLFVVSHISRDSPGKEQKYMLGADYQLTVKSLCASLLDTNVLVQRNNLEIILFFFPFYTCLDPDERAIPLLRRDVVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPEFVISSSYEDQSSYFFDKYSKNLLVEALSEILHQKFSDADIEERQHAYLKPFRILLSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGSDLKLSYTQSGNLLTSTIKENRHASEIVKTVNLLVSLLSTDFLWDYMARCFEECFRPVTQTAIGEAIGPPPTVAELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLAELTHALKTCFKVLSKVQMPPSYLDMAASSGNSSPVKGESSDIILETKASDEEAPFPPLKSEDSGIGLSASSPELSERLRVPRVSAERDDIWKKDGTMQRTFLCIQELIANFASKNIFAASLTVSGEESKPEEPPGKSDKGISHSGRKSSWDPKPITVPQFKQMLSDLFTARGSPFKTKSSESMSSVPSSPHRKAEAEWDIDEVVIELVGSKEDCREAFAAACHLLLDCATFPVYLSAEETEQLCEMLFQTSASDCSFPSWLKSLMTICCCVNDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTRETQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIHCLKQENSAEDLHRWFNRKRHTFKEACGISEPQEGTSEEHLPLGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDMPYYMDLPDRIASCGPDSSEHTESADTSSVHTDSENTSTFSSPSHDLQDLSHEENCCAPIPIGGKAYSKRAALLPTLQPESLKSSAKLGLVRADSDKTQASESLSSDEEADVELQAITTTSRLLRQQKEKQESLEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALVGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDVLGNRDVQVKSVEVLIRITTQLVSVAKSSEGKNVEFIHSLLQKCKVQEFVLLSLSASMYTSQKRYGLATADRGRVPMEVSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEDAQSQPALSREWQRALNFQQAIGAMQYVQPHPLPSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDELVKQYESESVKLSVSTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAISDPINLRNAKNAILEELPRIVNTMALIWNVLRKEDTQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTAHLGVQLIAAVATVWSRKQARRHSKTKIVPMASASQHTLVDLVCALSTLQTDSVLQLVKEVVKRPLQIKGDEKSPLVDIPVLQFCYAFIQRLSIPDLQENFPSLLGVLKESVQLNLAPPGYFLLLSILNDFVTRTPNPESKKDQKDLQEITQKILEAIGTIAGSSLEQTSWLSRNLEVRAQPQVSLEESDAEDDEHADTDAAVASAMVSASAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWKKEVLELFLDPAFFQMDTSCAHWKSIIDHLLTHEKTMFKDLMNMQSSSLKLFSSVDQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSTVAAQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFLQLEEDLKEEDESLRNSNKTNRIKVPVADGNGPSGGTVSPGDLIMYLSACKFLDTALSFPPDKMPLFQIYRWAFVPEVDTEHPTFLSELEENHQECRPHTVRILELLRSKYGETGSSDEITRESEFPLLRQHSVSSIRQLIPFFKTLNCAFKTQSHLPSDAPGTSVPELPVVDSPRVLRQLEECVEHDFLEYPEC", "length": 2290, "header": "tr|A0A9J7FYM7-1|A0A9J7FYM7_CRIGR Computationally mapped isoform of Protein dopey-2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Dop1b PE=3 SV=1 CANONICAL=A0A9J7FYG9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JI39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9/entry#A0A9J7JI39-1", "sequence": { "sequence": "MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLLISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYERYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYDRTDALLLRLSLVVGREVFYAALWGSVLTSPSIRLPASLFVVSHISRDSPGKEQKYMLGADYQLTVKSLCASLLDTNVLVQRNNLEIILFFFPFYTCLDPDERAIPLLRRDVVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPEFVISSSYEDQSSYFFDKYSKNLLVEALSEILHQKFSDADIEERQHAYLKPFRILLSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGSDLKLSYTQSGNLLTSTIKENRHASEIVKTVNLLVSLLSTDFLWDYMARCFEECFRPVTQTAIGEAIGPPPTVAELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLAELTHALKTCFKVLSKVQMPPSYLDMAASSGNSSPVKGESSDIILETKASDEEAPFPPLKSEDSGIGLSASSPELSERLRVPRVSAERDDIWKKDGTMQRTFLCIQELIANFASKNIFAASLTVSGEESKPEEPPGKSDKGISHSGRKSSWDPKPITVPQFKQMLSDLFTARGSPFKTKSSESMSSVPSSPHRKAEAEWDIDEVVIELVGSKEDCREAFAAACHLLLDCATFPVYLSAEETEQLCEMLFQTSEASDCSFPSWLKSLMTICCCVNDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTRETQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIHCLKQENSAEDLHRWFNRKRHTFKEACGISEPQEGTSEEHLPLGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDMPYYMDLPDRIASCGPDSSEHTESADTSSVHTDSENTSTFSSPSHDLQDLSHEENCCAPIPIGGKAYSKRAALLPTLQPESLKSSAKLGLVRADSDKTQASESLSSDEEADVELQAITTTSRLLRQQKEKQESLEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALVGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDVLGNRDVQVKSVEVLIRITTQLVSVAKSSEGKNVEFIHSLLQKCKVQEFVLLSLSASMYTSQKRYGLATADRGRVPMEVSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEDAQSQPALSREWQRALNFQQAIGAMQYVQPHPLPSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDELVKQYESESVKLSVSTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAISDPINLRNAKNAILEELPRIVNTMALIWNVLRKEDTQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTAHLGVQLIAAVATVWSRKQARRHSKTKIVPMASASQHTLVDLVCALSTLQTDSVLQLVKEVVKRPLQIKGDEKSPLVDIPVLQFCYAFIQRLSIPDLQENFPSLLGVLKESVQLNLAPPGYFLLLSILNDFVTRTPNPESKKDQKDLQEITQKILEAIGTIAGSSLEQTSWLSRNLEVRAQPQVSLEESDAEDDEHENVPRTVVRPATLCKSRSQKPCGKDCRGLCTRKGTDLAAALIERSDLSSGPAVDLQTQMLLWLPQWCQLLLPLFTVCKHSLSWQRFWLLSWTWFIEVMRKRRPCH", "length": 1972, "header": "tr|A0A9J7JI39-1|A0A9J7JI39_CRIGR Computationally mapped isoform of Protein dopey-2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Dop1b PE=3 SV=1 CANONICAL=A0A9J7FYG9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9/entry#A0A9J7JQU9-1", "sequence": { "sequence": "MARCFEECFRPVTQTAIGEAIGPPPTVAELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLAELTHALKTCFKVLSKVQMPPSYLDMAASSGNSSPVKGESSDIILETKASDEEAPFPPLKSEDSGIGLSASSPELSERLRVPRVSAERDDIWKKDGTMQRTFLCIQELIANFASKNIFAASLTVSGEESKPEEPPGKSDKGISHSGRKSSWDPKPITVPQFKQMLSDLFTARGSPFKTKSSESMSSVPSSPHRKAEAEWDIDEVVIELVGSKEDCREAFAAACHLLLDCATFPVYLSAEETEQLCEMLFQTSEASDCSFPSWLKSLMTICCCVNDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTRETQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIHCLKQENSAEDLHRWFNRKRHTFKEACGISEPQEGTSEEHLPLGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDMPYYMDLPDRIASCGPDSSEHTESADTSSVHTDSENTSTFSSPSHDLQDLSHEENCCAPIPIGGKAYSKRAALLPTLQPESLKSSAKLGLVRADSDKTQASESLSSDEEADVELQAITTTSRLLRQQKEKQESLEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALVGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDVLGNRDVQVKSVEVLIRITTQLVSVAKSSEGKNVEFIHSLLQKCKVQEFVLLSLSASMYTSQKRYGLATADRGRVPMEVSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEDAQSQPALSREWQRALNFQQAIGAMQYVQPHPLPSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDELVKQYESESVKLSVSTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAISDPINLRNAKNAILEELPRIVNTMALIWNVLRKEDTQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTAHLGVQLIAAVATVWSRKQARRHSKTKIVPMASASQHTLVDLVCALSTLQTDSVLQLVKEVVKRPLQIKGDEKSPLVDIPVLQFCYAFIQRLSIPDLQENFPSLLGVLKESVQLNLAPPGYFLLLSILNDFVTRTPNPESKKDQKDLQEITQKILEAIGTIAGSSLEQTSWLSRNLEVRAQPQVSLEESDAEDDEHADTDAAVASAMVSASAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWKKEVLELFLDPAFFQMDTSCAHWKSIIDHLLTHEKTMFKDLMNMQSSSLKLFSSVDQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSTVAAQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFLQLEEDLKEEDESLRNSNKTNRIKVPVADGNGPSGGTVSPGDLIMYLSACKFLDTALSFPPDKMPLFQIYRWAFVPEVDTEHPTFLSELEENHQECRPHTVRILELLRSKYGETGSSDEITRESEFPLLRQHSVSSIRQLIPFFKTLNCAFKTQSHLPSDAPGTSVPELPVVDSPRVLRQLEECVEHDFLEYPEC", "length": 1844, "header": "tr|A0A9J7JQU9-1|A0A9J7JQU9_CRIGR Computationally mapped isoform of Protein dopey-2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Dop1b PE=4 SV=1 CANONICAL=A0A9J7FYG9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 473, "start_aa": "Thr", "end_pos": 473, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr473", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751759", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751759", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LFK5-1", "protein_name": "DOP1 leucine zipper like protein B", "gene_name": "Dop1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPEEQELLTDYRYRSYASVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLIISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYEKYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYERTDTLLLRLSVVVGREVFYAALWGSVLTSPSIRLPASLFVVNHISRDSPGKEQKYMLGTDYQLTVRALCASLLDANVLVQRNNLEITLFFFPFYTCLDPDERAIPLLRRDIVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPKSEISSSYEDQCSYFFDKYSKDLLVEALAEILHQKFLNADLEERHHEYLKPFRILVSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGPDLRLSYTQSGNLLTSTIKENRHASEIVKTVNLLVSSLSTDFLWDYMARCFEECFRPVTQTTAIGEAISPPPTVSELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLPELTHALKTCFKVLSKVQMPPSYLDMEPTSGNSSPIKGRNSGVLETEAVVAGDEEPSFPPLKSEDSGIGLSASSPELSEHLRVPRVSAERDDIWKKDGNMQATFLCIQELIANFANKNIFAASLTVSGEESKPEGAPGKSIRGQTQSTEHSGRKSSWEPKPITVPQFKQMLSDLFTVRGSPFKTRSSESLSSAPSSPHRKAAAEWDVDQVVIELVGSKEDCREALAAACHLLLDCATFPVYLSEEETQQLCEMLFQTPGPSDCSFPPWLKSLMTICCCVNDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIQCLKQENSAEGLHRWFNRKKPACREACGESELQEGAPEEHLPRGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDLPYYVDLPDRMASGGGDSSEHTESADTSSGHTDSENTSTFSSPSHDLQDLSHEENCCAPIPVGGRAYSKRAALLAAFQPESPRSNARLSLVRADSDKTQASESFSSDEEAEVELQAITTSRLLKQQREKQETVEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDILGNRDVQVKSVEVLIRITTQLVSMAKSSEGKNVEFIHSLLQRCKVQEFVLLSLSASMYTSQKRYGLATADRGGRVFVEDSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEDSESQPALSREWQRALNFQQAIGAMQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDDLVKQYESESVKFTVSTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAVSDPINLRNAKNAILEELPRIVNTMALIWNVLKKEETQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTGHLGVQLIAAVATVWSRKQSRRHSKTKMVPVASASQHTLVDLVCALSTLQTDSVLQLVKEVVKKPAQIKGDEKSPLVDIPVLQFCYAFIQRGGVTKVEQETVRLSIPDLQEAFPSLLGVLKEAVQLNLAPPGYFLLLSMLNDFVTRTPNLESKKDQKDLQEITQRILEAVGTIAGSSLEQTSWLSRNLEVKAQPQVSLEDSDADEDVCDAAAASTMVSASAPSIYSVQALSLLAEVLASLLDMVYRSDEKERAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYSKRAWKKEVLELFLDPAFFQMDSSCVHWKSIIDHLLTHEKTMFKDLMNMQSSSLKLFSSFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSIVAGQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFIQLEEDLKEEEESRNSNKINRVKVPAADGTGPSGGAVTPSDLIMYLSACKFLDTALSFPPDKMPLFQIYRWAFVPEVDTEHPAFLSELEENHQECRPHTVRILELLRLKYGEISSSEEITRKKEFPLLRQHSVSCIRQLIPFFRTLNCAFKTQSQLPADVPGTTVPEFPVADSLRVLQQLEECVEQDFLEYPEC", "length": 2306 }, "evidence": [ { "id": "A0A9J7FYG9", "url": "https://omabrowser.org/oma/group/A0A9J7FYG9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UHQ6-1", "protein_name": "Protein DOP1B", "gene_name": "Dop1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLIISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYEKYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYERTDALLLRLSVVVGREVFYAALWGSVLTSPSIRLPASLFVVNHISRDSPGKEQKCMLGTDYQLTVRSLCASLLDANVLVQRNNLEIILFFFPFYTCLDPEERAIPLLRRDVVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPKSEISNSYEDQCSYFFDKYSKDLLVEALAEILHQKFLDADLEERHHAYLKPFRILVSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGSDLKLSYTQSGNPLISTIKENRHASEIVKTVNLLVSSLSSDFLWDYMARRFEACFRPVTQTTAIGEAISPPPTVSELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLPELTHALKTCFKVLSKVQMPPSYLDLEPSSGNSSPVKGRNSGIAMETEAVVAGDEEPSFPPLKSEDSGIGLSASSPELSEHLRVPRVSAERDDIWKKDGTMQATFLCIQELIANFASKNIFAASLTVSGEENKPEEPPGKGNKGQTQSTEHPGRKSSWDPKPITVPQFKQMLSDLFTVRGSPFKTRSSESLSSVPSSPHRKAATEWGVDQVVVELVGSKEDCREALAAACHLLLDCATFPVYLSEEETEQLCETLFQTPGASDCSFPPWLKSLMTICCCVSDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIQCLKQENSAEDLHRWFNRKKPTCKEACGESEPQEGAPEERLPRGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDLPYYVDLPDRMTSGGGDSSEHTESADTSSGHTDSENTSTFSSPSHDLQDLSHEENCCAPIPIGGRAYSKRAALLAAFQPESPRSNARLSLVRADSDKTQASESFSSDEEADVELQAITTSRLLKQQREKQETVEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDILGNRDVQVKSVEVLIRITAQLVSMAKSAEGKNTEFIHSLLQRCKVQEFVLLSLSASMYTSQKRYGLATADRGGRLLAEDSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEEAETQPALSREWQRALNFQQAIGAMQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDDLVKQYESESVKFTISTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAVSDPINLRNAKNAILEELPRIVNTMALIWNVLRKEETQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTGHLGVQLIAAVATVWNRKQARRHSKTKMVPVANTSQHTLVDLVCALSTLQTDSVLQLVKEVVKRPAQIKGDEKSPLVDIPVLQFCYAFIQRLSIPDLQEAFPSLLGVLKEAAQLNLAPPGYFLLLSMLNDFVTRTPNLESKKDQKDLQEITQRILEAVGTIAGSSLEQTSWLSRNLEVKAQPQVSLEESDAEDDVHSAAEASTMVSASAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWKKEVLELFLDPAFFQMDTSCVHWKSVIDHLLTHEKTMFKDLMNMQSSSLKLFSSFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSIVAGQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFIQLEEDLKEEDESRNSHKSNRIKAPVADGNGSAGRVLSPSDLTMYLSACKFLDTALAFPPDKMPLFQIYRWAFVPEVDTEHPAFLSELEENHQECRPHTVRILELLRSRYGEIGSSDEITRKKEFPLLRQHSVSCIRQLIPFFTTLNCAFKTQSQLPADVPGTAAPECPVTENPRVLRQLEECVEQDFLEHPEC", "length": 2295 }, "evidence": [ { "id": "A0A9J7FYG9", "url": "https://omabrowser.org/oma/group/A0A9J7FYG9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3R5-1", "protein_name": "Protein DOP1B", "gene_name": "DOP1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLRYSLLPRRLLISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAHAAVSVRPVLLTLYEKYFLPLQKLLLPSLQAFIVGLLPGLEEGSEISDRTDALLLRLSLVVGKEVFYTALWGSVLASPSIRLPASVFVVGHINRDAPGREQKYMLGTNHQLTVKSLRASLLDSNVLVQRNNLEIVLFFFPFYTCLDSNERAIPLLRSDIVRILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTVVPESEISNSYEDQSSYFFEKYSKDLLVEGLAEILHQKFIDADVEERHHAYLKPFRVLISLLDKPEIGPQVVGNLFLEVIRAFYSYCRDALGSDLKLSYTQSGNSLISAIKENRNASEIVKTVNLLITSLSTDFLWDYMTRCFEECFRPVKQRYSVRNSVSPPPTVSELCALLVFLLDVIPLELYSEVQTQYLPQVLGCLVQPLAEDMEALSLPELTHALKTCFKVLSKVQMPPSYLDTESTSGTSSPVKGENGKIILETKAVIPGDEDASFPPLKSEDSGIGLSASSPELSEHLRVPRVSLERDDVWKKGGSMQRTFLCIQELIANFASKNIFGVQLTASGEESKSEEPAGKRDRDGTQSLAANDSSRKNSWEPKPITVPQFKQMLSDLFTARGSPFKTKSSESPSSSPSSPARKNGGEWDVEKVVIDLGGSREERREAFAAACHLLLDCATFPVYLSEEETEQLCATLFQLPGAGDSSFPSWLKSLMTICCCVTDCYLQNVAISTLLEVINHSQSLALVIEDKMKRYKSSGHNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHVTCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLACTDGAIGAAAQGWLVRALSLGDVARILEPVLLLLLQPKTQRTSIHCLKQENSADDLHRWFNRKKTSFREACAVPEPQESGSEEHLPLSQFTTVDREAIWAEVEKEPEKYPLRGELSEEELPYYVELPDRTAHGAPDSSEHTESADTSSCHTDSENTSSFSSPSHDLQELSNEENCCAPIPMGGRAYPKRSALLAAFQSESFKAGAKLSLVRVDSDKTQASESFSSDEEADLELQALTTSRLLKQQRERQEAVEALFKHILLYLQPYDSRRVLYAFSVLEAVLKTNPKEFIEAVSRTSMDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQVPNVCPHSLLLELLTYLCLSFLRSYYPCYLKVSHRDILGNRDVQVKSVEVLIRIMMQLVSVAKSSEGKNVEFIHSLLQRCKVQEFVLLSLSASMYTSQKRYGLATAHHGRALPEDSLFEESLINLGQDQIWSEHPLQIELLKLLQVLIVLEHHLGRAHEEAENQPDLSREWQRALNFQQAISALQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVVQICKNLDDLVKQYESESVKLSVSTTSKRENISPDYPLTLLEGLTTISHFCLLEQANQNKKTMAAGDPANLRNARNAILEELPRTVNTMALLWNVLRKEETQKRPVDLLGATKGSSSVYFKTTKTIRQKILDFLNPLTAHLGVQLTAAVAAVWSRKKAQRHSKMKIIPTASASQLTLVDLVCALSTLQTDTLLHLVKEVVKRPPQVKGGDEKSPLVDIPVLQFCYAFLQRLPVPALQENFSSLLGVLKESVQLNLAPPGYFLLLSMLNDFVTRTPNLENKKDQKDLQEITQKILEAVGNIAGSSLEQTSWLSRNLEVKAQPQASLEESDAEEDLYDAAAASAMVSSSAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWRKEVLELFLDPAFFQMDTSCVHWKSIIDHLLTHEKTMFKDLMNMQSSSLKLFSSFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSIVAAQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFTQLEEDLKDEDESLRSTNKVNRTKVSVPDANGPSVGEIPQSELILYLSACKFLDTALSFPPDKMPLFQIYRWAFIPEVDTEGPAFLSDVEENHQECKPHTVRILELLKLKFGEISSSDEITMKSEFPLLRQHSVSSIRQLMPFFMTLNGAFKTQRQLPADSPGTPFLDFPVTDSPRILKQLEECIEYDFLEHPEC", "length": 2298 }, "evidence": [ { "id": "A0A9J7FYG9", "url": "https://omabrowser.org/oma/group/A0A9J7FYG9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYG9" } ], "pmid": "" }, { "name": "trans-Golgi 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268207" } ] }, { "annotation": "Has peptide-independent ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYI4#function" }, { "database": "UniProtKB", "id": "ARBA00002077", "url": "https://www.uniprot.org/uniprotkb/ARBA00002077#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYI4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hspa13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYI4", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10237", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10237", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766580", "url": "https://www.ncbi.nlm.nih.gov/gene/100766580", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766580", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766580", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FYI4", "url": "https://www.orthodb.org/?gene=A0A9J7FYI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19375", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19375", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268207", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268207", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FYI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGEMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHLSIPSMVSFTDGDVYVGYESLELADSNPQNTIYDAKRFIGKIFTPEELEAEIGRYPFKVLHKNGMAEFSVTSNETIIVSPEYVGSRLLLKLKKMAEEYLGMPVANAVISVPAEFDLKQRNSTIQAANLAGLKILRVINEPTAAAMAYGLHKVDVFYVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFLPSRKEEIHRLRQAVEMVKLNLTLHQSAHVSVLLTVEEKNSQTPQKDDSNLPKDQLSPGDGHHVNRVFRPGPSNSKSGERQVLFETEVSRKLFDSINEDLFQKILVPIQQVLKEGHLDKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN", "length": 471, "header": "tr|A0A9J7FYI4-1|A0A9J7FYI4_CRIGR Isoform 1 of Heat shock 70 kDa protein 13 OS=Cricetulus griseus OX=10029 GN=Hspa13 PE=3 SV=1 CANONICAL=A0A9J7FYI4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYI4/entry#A0A9J7FYI4-1", "sequence": { "sequence": "MAGEMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHLSIPSMVSFTDGDVYVGYESLELADSNPQNTIYDAKRFIGKIFTPEELEAEIGRYPFKVLHKNGMAEFSVTSNETIIVSPEYVGSRLLLKLKKMAEEYLGMPVANAVISVPAEFDLKQRNSTIQAANLAGLKILRVINEPTAAAMAYGLHKVDVFYVLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFLPSRKEEIHRLRQAVEMVKLNLTLHQSAHVSVLLTVEEKNSQTPQKDDSNLPKDQLSPGDGHHVNRVFRPGPSNSKSGERQVLFETEVSRKLFDSINEDLFQKILVPIQQVLKEGHLDKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN", "length": 471, "header": "tr|A0A9J7FYI4-1|A0A9J7FYI4_CRIGR Isoform 1 of Heat shock 70 kDa protein 13 OS=Cricetulus griseus OX=10029 GN=Hspa13 PE=3 SV=1 CANONICAL=A0A9J7FYI4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6/entry#names_and_taxonomy" } ] }, { "name": "hormonally up-regulated neu tumor-associated kinase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027271370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271370" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271370", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271370" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hunk", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYJ6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYJ6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14070", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14070", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"MPAAAGDGLLGEPAAPGGDGATEDAARPAAACEGSFLPAWVSGVSRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAINFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVSYPNRISLEDLSPSVVLHMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLSGKSDIQDGVCYKTQLYQIEKCRATKEPYEASLDTWTRDLEFHAVQDKKPKEQEKRGDFLHRPFSKKLDKSLPPHKQPSASLTTQIQNTKALLKDRKASKAGFPDKDSFGCRNLFRKTSDSNCVASSSMEFIPVPPPRTPRIVKKLEPHQSGPGSASILPKEEPLLLDMVRSFESVDREDHIELLSPSHHYRILSSPVSLARRNSSERTLSPGLLSGSTSPLQTPLHSTLVSFGHEDKNSSPKEEGVCSPPPAPSNGLTQPLGSPNCVKSRGRFPMMGIGQMLRKRHQSLQPSLERSLEASMSPLQPTAPSSLSFDMADGVKSQC", "length": 714, "header": "tr|A0A9J7FYJ6-1|A0A9J7FYJ6_CRIGR Isoform 1 of Hormonally up-regulated neu tumor-associated kinase OS=Cricetulus griseus OX=10029 GN=Hunk PE=3 SV=1 CANONICAL=A0A9J7FYJ6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYJ6-1", "url": 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765960", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765960", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { 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"https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] } ] }, { "uniprot_ac": "A0A8C2N3U2", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] }, { "uniprot_ac": "A0A8C2N6L4", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] } ] }, { "uniprot_ac": "A0A8C2N756", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] } ] }, { "uniprot_ac": "A0A8C2N9X1", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] } ] }, { "uniprot_ac": "A0A8C2QDX9", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] } ] }, { "uniprot_ac": "A0A8C2QEB8", "gene_name": "Bub1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] } ] }, { "uniprot_ac": "A0A8C2QGY5", "gene_name": "Ttbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] } ] }, { "uniprot_ac": "A0A8C2QH69", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] } ] }, { "uniprot_ac": "A0A8C2QHF9", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] } ] }, { "uniprot_ac": "A0A8C2QHS8", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] } ] }, { "uniprot_ac": "A0A8C2QJ34", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] } ] }, { "uniprot_ac": "A0A8C2QJA4", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] } ] }, { "uniprot_ac": "A0A8C2QKP7", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] } ] }, { "uniprot_ac": "A0A8C2QL63", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] } ] }, { "uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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} ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ 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"https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", 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"MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR", "length": 597, "header": "tr|A0A9J7FYL8-1|A0A9J7FYL8_CRIGR Isoform 1 of Tyrosine-protein phosphatase non-receptor type OS=Cricetulus griseus OX=10029 GN=Ptpn11 PE=3 SV=1 CANONICAL=A0A9J7FYL8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8/entry#A0A9J7FYL8-1", "sequence": { "sequence": "MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR", "length": 597, "header": "tr|A0A9J7FYL8-1|A0A9J7FYL8_CRIGR Isoform 1 of Tyrosine-protein phosphatase non-receptor type OS=Cricetulus griseus OX=10029 GN=Ptpn11 PE=3 SV=1 CANONICAL=A0A9J7FYL8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8/entry#A0A9J7FYQ1-1", "sequence": { "sequence": "MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR", "length": 593, "header": "tr|A0A9J7FYQ1-1|A0A9J7FYQ1_CRIGR Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type OS=Cricetulus griseus OX=10029 GN=Ptpn11 PE=3 SV=1 CANONICAL=A0A9J7FYL8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 570, "start_aa": "Thr", "end_pos": 570, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr570", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771077", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771077", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of ERK1 and ERK2 cascade", "id": "GO:0070374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070374", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ], "pmid": "" }, { "name": "receptor tyrosine kinase binding", "id": "GO:0030971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030971", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine phosphatase activity", "id": "GO:0004726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004726", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYL8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H060-1", "G3H622-1", "G3H9Q0-1", "A0A8C2LH05-1", "G3HKY7-1", "G3GWQ6-1", "G3HBF6-1", "G3GRD1-1", "G3H8H2-1", "A0A9J7FG56-1", "A0A061IAM9-1", "A0A9J7GE78-1", "A0A9J7GZK0-1", "A0A061HX98-1", "A0A061HZS8-1", "A0A3L7HEJ5-1", "A0A8C2LYZ8-1", "A0A9J7JC04-1", "A0A8C2MQ28-1", "A0A3L7I231-1", "A0A9J7EY47-1", "A0A8C2LVB9-1", "A0A8C2MZ43-1", "A0A9J7G003-1", "A0A8C2QC02-1", "A0A9J7JD11-1", "A0A8C2QH88-1", "A0A9J7EXY7-1", "A0A9J7JC62-1", "A0A9J7FEN1-1", "A0A9J7FB56-1", "A0A9J7FEZ5-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FWX7-1", "A0A9J7G1A0-1", "A0A9J7JTT7-1", "A0A9J7G7L1-1", "A0A9J7G7K2-1", "A0A9J7GNR2-1", "A0A9J7JU39-1", "A0A9J7KAX8-1", "A0A9J7GQG9-1", "A0A9J7GX92-1", "A0A9J7F2A0-1", "A0A9J7EZC9-1", "A0A9J7EZL1-1", "A0A9J7FIV0-1", "A0A8C2MFV5-1", "A0A8C2N2E5-1", "A0A8C2N686-1", "A0A8C2QCP2-1", "A0A3L7IA07-1", "A0A9J7FYL8-1", "A0A9J7G168-1", "A0A9J7GBQ5-1", "A0A9J7H7L7-1", "A0A9J7HBK7-1", "A0A9J7GQC8-1", "A0A9J7H152-1", "A0A9J7KDA7-1", "A0A9J7KDM0-1", "A0A9J7J766-1", "A0A9J7FKB3-1", "A0A3L7HAL2-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061HZS8", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] } ] }, { "uniprot_ac": "A0A061IAM9", "gene_name": "LOC100766206", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] } ] }, { "uniprot_ac": "A0A3L7HAL2", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7I231", "gene_name": "Ptp4a3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] } ] }, { "uniprot_ac": "A0A3L7IA07", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] } ] }, { "uniprot_ac": "A0A8C2LH05", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYZ8", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] } ] }, { "uniprot_ac": "A0A8C2MFV5", "gene_name": "LOC100758361", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] } ] }, { "uniprot_ac": "A0A8C2MQ28", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] } ] }, { "uniprot_ac": "A0A8C2MZ43", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2N686", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] } ] }, { "uniprot_ac": "A0A8C2QC02", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EXY7", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZC9", "gene_name": "Ptpn18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F2A0", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] } ] }, { "uniprot_ac": "A0A9J7FB56", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] } ] }, { "uniprot_ac": "A0A9J7FEN1", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] } ] }, { "uniprot_ac": "A0A9J7FEZ5", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] } ] }, { "uniprot_ac": "A0A9J7FG56", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] } ] }, { "uniprot_ac": "A0A9J7FIV0", "gene_name": "LOC100763249", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FWX7", "gene_name": "LOC103158664", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] } ] }, { "uniprot_ac": "A0A9J7FYL8", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] } ] }, { "uniprot_ac": "A0A9J7G003", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] } ] }, { "uniprot_ac": "A0A9J7G168", "gene_name": "LOC100762307", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] } ] }, { "uniprot_ac": "A0A9J7G1A0", "gene_name": "Ptpn4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] } ] }, { "uniprot_ac": "A0A9J7G7K2", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] } ] }, { "uniprot_ac": "A0A9J7G7L1", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] } ] }, { "uniprot_ac": "A0A9J7GBQ5", "gene_name": "LOC100764354", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GNR2", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] } ] }, { "uniprot_ac": "A0A9J7GQC8", "gene_name": "LOC100757114", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] } ] }, { "uniprot_ac": "A0A9J7GQG9", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] } ] }, { "uniprot_ac": "A0A9J7GX92", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] } ] }, { "uniprot_ac": "A0A9J7GZK0", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] } ] }, { "uniprot_ac": "A0A9J7H152", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] } ] }, { "uniprot_ac": "A0A9J7H7L7", "gene_name": "Ptprh", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H7L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H7L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ] } ] }, { "uniprot_ac": "A0A9J7HBK7", "gene_name": "Ptpn22", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7HBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7HBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ] } ] }, { "uniprot_ac": "A0A9J7J766", "gene_name": "Ptpn20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] } ] }, { "uniprot_ac": "A0A9J7JC04", "gene_name": "Eya3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] } ] }, { "uniprot_ac": "A0A9J7JC62", "gene_name": "Tns2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] } ] }, { "uniprot_ac": "A0A9J7JD11", "gene_name": "Ptprm", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] } ] }, { "uniprot_ac": "A0A9J7JTT7", "gene_name": "Ptpra", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT7" } ] } ] }, { "uniprot_ac": "A0A9J7JU39", "gene_name": "Eya4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JU39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU39" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JU39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU39" } ] } ] }, { "uniprot_ac": "A0A9J7KAX8", "gene_name": "Eya2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KAX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KAX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX8" } ] } ] }, { "uniprot_ac": "A0A9J7KDA7", "gene_name": "Ptprb", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] } ] }, { "uniprot_ac": "A0A9J7KDM0", "gene_name": "LOC100769324", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ] } ] }, { "uniprot_ac": "G3GRD1", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] } ] }, { "uniprot_ac": "G3GWQ6", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] } ] }, { "uniprot_ac": "G3H060", "gene_name": "Dusp26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] } ] }, { "uniprot_ac": "G3H622", "gene_name": "Dusp4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] } ] }, { "uniprot_ac": "G3H8H2", "gene_name": "Dusp19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H8H2", "database": 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eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613692.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498502", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498502" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYP3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYP3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100771947", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYP3", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYP3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04269", "database": "CDD", "categories": [ "Protein 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"categories": [ "Protein Classification" ] }, { "id": "IPR034027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771947", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771947", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FYP3", "url": "https://www.orthodb.org/?gene=A0A9J7FYP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": 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"MSVAASVKGITSILSSLQITKVALKEAKITSHIWAAQQLNLGLRLVPGHPSVKIGILVLLIFLPSTFCDIGPVYYSSYETVIPKRLPVEGSEDPGGRVSYMLLIQGQQQLLHLKVKGDYSVNNFPVYSYHNGILEQEMPLLSQDCHYEGYMEGVPGSFVSVNICSGLRGILIKEDTSYSIEPILSSKGFEHILYTVGLQPQASCSVTPKGSSGDTSQQQRNGKPDDPWELSDLRSHTKYVEMFVVVNHQRFQMWGSSVNETVGAVVDIIALTNSFTRGLNTEVVLVGMEIWTEGDPIEAPVDLQATLRDFNRWRQEKLVGRLRHDVAHLIVGHHPGENEGQAFLHGACSGGFAAAVEAFPHEDVLLFAALMAHELGHNLGIQHDHQACICDHKHFCLMHENITKGSGFSNCSSDDFYRFLHDHRGACLLDRPWHQSRKRRATRCGNGVVEDWEQCDCGPACDHHPCCDPTCRLKLGAECSDGLCCYKCHVKKKGVLCRPVEDVCDLPEYCNGLSQECPANSYKQDGTLCDRIYYCSGGWCKNPDKQCTKIYGYPARSAPDDCYILMNTKGNRFGNCGHPTTANARYETCSDDDVFCGKLICTDVRYLPQVRPQHTLLQVPYGDDWCWSMDAYNITDVPDFGDVQSGTYCAPNKVCMEYYCTDHTVLQYNCKPEELCHGKGVCNNLRHCHCDDGFAPPDCNGPGDGGSVDSGPVGKPADRNLSLFVLFGDKTQSKADDEEVNMKVVVLVVPIFLVLLLCALMLIAYLWSEVQEAVSPGSSSSSSTETSEGAGQPPQRGVPSARPPPK", "length": 806, "header": "tr|A0A9J7FYP3-1|A0A9J7FYP3_CRIGR Isoform 1 of Disintegrin and metalloproteinase domain-containing protein 1a OS=Cricetulus griseus OX=10029 GN=LOC100771947 PE=4 SV=1 CANONICAL=A0A9J7FYP3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYP3/entry#A0A9J7FYP3-1", "sequence": { "sequence": "MSVAASVKGITSILSSLQITKVALKEAKITSHIWAAQQLNLGLRLVPGHPSVKIGILVLLIFLPSTFCDIGPVYYSSYETVIPKRLPVEGSEDPGGRVSYMLLIQGQQQLLHLKVKGDYSVNNFPVYSYHNGILEQEMPLLSQDCHYEGYMEGVPGSFVSVNICSGLRGILIKEDTSYSIEPILSSKGFEHILYTVGLQPQASCSVTPKGSSGDTSQQQRNGKPDDPWELSDLRSHTKYVEMFVVVNHQRFQMWGSSVNETVGAVVDIIALTNSFTRGLNTEVVLVGMEIWTEGDPIEAPVDLQATLRDFNRWRQEKLVGRLRHDVAHLIVGHHPGENEGQAFLHGACSGGFAAAVEAFPHEDVLLFAALMAHELGHNLGIQHDHQACICDHKHFCLMHENITKGSGFSNCSSDDFYRFLHDHRGACLLDRPWHQSRKRRATRCGNGVVEDWEQCDCGPACDHHPCCDPTCRLKLGAECSDGLCCYKCHVKKKGVLCRPVEDVCDLPEYCNGLSQECPANSYKQDGTLCDRIYYCSGGWCKNPDKQCTKIYGYPARSAPDDCYILMNTKGNRFGNCGHPTTANARYETCSDDDVFCGKLICTDVRYLPQVRPQHTLLQVPYGDDWCWSMDAYNITDVPDFGDVQSGTYCAPNKVCMEYYCTDHTVLQYNCKPEELCHGKGVCNNLRHCHCDDGFAPPDCNGPGDGGSVDSGPVGKPADRNLSLFVLFGDKTQSKADDEEVNMKVVVLVVPIFLVLLLCALMLIAYLWSEVQEAVSPGSSSSSSTETSEGAGQPPQRGVPSARPPPK", "length": 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYS2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYS2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"UniProtKB", "id": "A0A9J7FYS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYS4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FYS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYS4" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FYW4-1", "uniprot_ac": "A0A9J7FYW4", "uniprot_id": "A0A9J7FYW4_CRIGR", "mass": { "chemical_mass": 134933.0, "monoisotopic_mass": 134933.0 }, "refseq": { "ac": "XP_027272461", "name": "protein jagged-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272461" }, "gene_names": [ { "name": "Jag2", "type": "recommended", "evidence": [ { "id": "A0A9J7FYW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4" } ] }, { "name": "Jag2", "type": "synonym", "evidence": [ { "id": "XP_027272461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272461" } ] } ], "protein_names": [ { "name": "Delta-like protein", "type": "recommended", "evidence": [ { "id": "A0A9J7FYW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4/entry#names_and_taxonomy" } ] }, { "name": "protein jagged-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027272461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272461" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272461", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272461" } ] }, { "annotation": "Putative Notch ligand involved in the mediation of Notch signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4#function" }, { "database": "UniProtKB", "id": "RU280815", "url": "https://www.uniprot.org/uniprotkb/RU280815#function" }, { "database": "UniProtKB", "id": "A0A9J7G303", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G303#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Jag2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4", "locus": {} } ], "crossref": [ { "id": "A0A9J7FYW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FYW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753300", "url": "https://www.ncbi.nlm.nih.gov/gene/100753300", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": 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[ "Protein Classification" ] }, { "id": "PTHR12916:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12916:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07657", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07657", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07974", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12661", 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"MRARGRGRLPGRLRLLLLLLCVQAARPMGYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGRDECDTYVRVCLKEYQAKVTPTGPCSYGYGATPVLGGNSFYLPPAGAAGDRARARSRTGGHQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPDEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSPTCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSCVEPWHCDCETNWGGLLCDKDLNYCGSHHPCVNGGTCINAEPDQYLCACPDGYLGKNCERAEHACASNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCLPGWKGINCHININDCHGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELEYDKCASSPCRRGGVCEDLVDGFRCHCPRGLSGLLCEVDVDLCEPSPCLNGAHCYNLEDDYYCACPEDFGGKNCSVPRETCPGGACRVIDGCGFEAGSRTHGVAPSGICGPHGHCVSLPGGNFSCVCDSGFTGTYCHENIDDCMGQPCRNGGTCIDEVDSFRCFCPSGWEGELCDINPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDIYTCSNGGTCYDNGDTFRCACPPGWKGSTCTIAKNSSCLPNPCVNGGTCVGSGDSFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCNCPPGRSGPRCQEVVIFRRPCWSRGMSFPHGSSWIEDCNSCRCLDGRRDCSKVWCGWKPCLLSGQPNALSAQCPPGQQCQEKALGQCLQPPCENWGECAAEEPLPPSTPCLPRTTHLDNNCARLTLRFNRDQVPQGTTVGAICSGIRALPATRAVAHDRLLLLLCDRASSGASAVEVAVSFSPARDLTDSSLIQSTAHAIVAAITQRGNSSLLLAVTEVKVETVVMGGSSTGLLVPVLCSVFSVLWLVCVVICVWWTRKRRKERERSRLPRDESANNQWAPLNPIRNPIERPGSSGLGTGGHKDVLYQCKNFTPPPRRAGEALPGPAGHGAVGEDEEDEELGREDGDSPEAEKFLSHKFTKDPSCSLGRPACWAPGPKVDNRAVKSTKDVRCAGRE", "length": 1248, "header": "tr|A0A9J7FYW4-1|A0A9J7FYW4_CRIGR Isoform 1 of Delta-like protein OS=Cricetulus griseus OX=10029 GN=Jag2 PE=4 SV=1 CANONICAL=A0A9J7FYW4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G303-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4/entry#A0A9J7G303-1", "sequence": { "sequence": "MRARGRGRLPGRLRLLLLLLCVQAARPMGYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGRDECDTYVRVCLKEYQAKVTPTGPCSYGYGATPVLGGNSFYLPPAGAAGDRARARSRTGGHQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPDEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSPTCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSCVEPWHCDCETNWGGLLCDKDLNYCGSHHPCVNGGTCINAEPDQYLCACPDGYLGKNCERAEHACASNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDINDCHGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELEYDKCASSPCRRGGVCEDLVDGFRCHCPRGLSGLLCEVDVDLCEPSPCLNGAHCYNLEDDYYCACPEDFGGKNCSVPRETCPGGACRVIDGCGFEAGSRTHGVAPSGICGPHGHCVSLPGGNFSCVCDSGFTGTYCHENIDDCMGQPCRNGGTCIDEVDSFRCFCPSGWEGELCDINPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDIYTCSNGGTCYDNGDTFRCACPPGWKGSTCTIAKNSSCLPNPCVNGGTCVGSGDSFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCNCPPGRSGPRCQEVVIFRRPCWSRGMSFPHGSSWIEDCNSCRCLDGRRDCSKVWCGWKPCLLSGQPNALSAQCPPGQQCQEKALGQCLQPPCENWGECAAEEPLPPSTPCLPRTTHLDNNCARLTLRFNRDQVPQGTTVGAICSGIRALPATRAVAHDRLLLLLCDRASSGASAVEVAVSFSPARDLTDSSLIQSTAHAIVAAITQRGNSSLLLAVTEVKVETVVMGGSSTGLLVPVLCSVFSVLWLVCVVICVWWTRKRRKERERSRLPRDESANNQWAPLNPIRNPIERPGSSGLGTGGHKDVLYQCKNFTPPPRRAGEALPGPAGHGAVGEDEEDEELGREDGDSPEAEKFLSHKFTKDPSCSLGRPACWAPGPKVDNRAVKSTKDVRCAGRE", "length": 1210, "header": "tr|A0A9J7G303-1|A0A9J7G303_CRIGR Computationally mapped isoform of Delta-like protein OS=Cricetulus griseus OX=10029 GN=Jag2 PE=4 SV=1 CANONICAL=A0A9J7FYW4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753300", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753300", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4" } ], "pmid": "" }, { "name": "Notch binding", "id": "GO:0005112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005112", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1061, "end_pos": 1063, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1163, "end_pos": 1165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FYW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4" }, { "id": "PS51051", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51051" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DSL", "eco_id": "ECO_0000259", "start_pos": 197, "end_pos": 241, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FYW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYW4" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 308, "end_pos": 346, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 382 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1061, "end_pos": 1063 }, { "start_pos": 1163, "end_pos": 1165 }, { "start_pos": 154, "end_pos": 156 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 620, "end_pos": 622 }, { "start_pos": 753, "end_pos": 755 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FZ03-1", "uniprot_ac": "A0A9J7FZ03", "uniprot_id": "A0A9J7FZ03_CRIGR", "mass": { "chemical_mass": 37987.0, "monoisotopic_mass": 37987.0 }, "refseq": { "ac": "XP_027269333", "name": "guanine nucleotide-binding protein subunit alpha-12 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269333" }, "gene_names": [ { "name": "Gna12", "type": "recommended", "evidence": [ { "id": "A0A9J7FZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ] }, { "name": "Gna12", "type": "synonym", "evidence": [ { "id": "XP_027269333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269333" } ] } ], "protein_names": [ { "name": "Guanine nucleotide-binding protein subunit alpha-12 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7FZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide-binding protein subunit alpha-12 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027269333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269333" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 9% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027269333.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269333" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gna12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03", "locus": {} } ], "crossref": [ { "id": "A0A9J7FZ03", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FZ03", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00066", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00066", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760944", "url": "https://www.ncbi.nlm.nih.gov/gene/100760944", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760944", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760944", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FZ03", "url": "https://www.orthodb.org/?gene=A0A9J7FZ03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10218:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10218:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00503", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00503", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269333", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ03-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGASVREDYKRVLVALKLGLQTVMSQPKSPLWPESTQLNFLSLLTSFQGSRVLVDARDKLGIPWQHSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKSVSIKKHFPDFKGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENIRFVFHAVKDTILQENLKDIMLQ", "length": 326, "header": "tr|A0A9J7FZ03-1|A0A9J7FZ03_CRIGR Isoform 1 of Guanine nucleotide-binding protein subunit alpha-12 isoform X3 OS=Cricetulus griseus OX=10029 GN=Gna12 PE=3 SV=1 CANONICAL=A0A9J7FZ03-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZ03-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03/entry#A0A9J7FZ03-1", "sequence": { "sequence": "MGASVREDYKRVLVALKLGLQTVMSQPKSPLWPESTQLNFLSLLTSFQGSRVLVDARDKLGIPWQHSENEKHGMFLMAFENKAGLPVEPATFQLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKSVSIKKHFPDFKGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTTAIDTENIRFVFHAVKDTILQENLKDIMLQ", "length": 326, "header": "tr|A0A9J7FZ03-1|A0A9J7FZ03_CRIGR Isoform 1 of Guanine nucleotide-binding protein subunit alpha-12 isoform X3 OS=Cricetulus griseus OX=10029 GN=Gna12 PE=3 SV=1 CANONICAL=A0A9J7FZ03-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760944", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760944", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "D5 dopamine receptor binding", "id": "GO:0031752", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031752", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "pmid": "" }, { "name": "G-protein beta/gamma-subunit complex binding", "id": "GO:0031683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031683", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "pmid": "" }, { "name": "brush border membrane", "id": "GO:0031526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031526", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "pmid": "" }, { "name": "heterotrimeric G-protein complex", "id": "GO:0005834", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005834", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "pmid": "" }, { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A9J7FZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03#function" }, { "id": "A0A9J7FZ03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ03" }, { "id": "PIRSR601019-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR601019-2" } ], "binding_site_uniprot": 153, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 153, "end_pos": 153, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 286, "end_pos": 288 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FZ21-1", "uniprot_ac": "A0A9J7FZ21", "uniprot_id": "A0A9J7FZ21_CRIGR", "mass": { "chemical_mass": 44693.0, "monoisotopic_mass": 44693.0 }, "refseq": { "ac": "XP_027271909", "name": "neutrophil cytosol factor 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271909" }, "gene_names": [ { "name": "Ncf1", "type": "recommended", "evidence": [ { "id": "A0A9J7FZ21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ] }, { "name": "Ncf1", "type": "synonym", "evidence": [ { "id": "XP_027271909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271909" } ] } ], "protein_names": [ { "name": "Neutrophil cytosol factor 1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7FZ21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21/entry#names_and_taxonomy" } ] }, { "name": "neutrophil cytosol factor 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027271909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271909" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271909" } ] }, { "annotation": "Subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane. This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21#function" }, { "database": "UniProtKB", "id": "ARBA00057303", "url": "https://www.uniprot.org/uniprotkb/ARBA00057303#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ncf1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21", "locus": {} } ], "crossref": [ { "id": "A0A9J7FZ21", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FZ21", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06887", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06887", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12021", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12021", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12022", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12022", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769204", "url": "https://www.ncbi.nlm.nih.gov/gene/100769204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051228", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051228", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769204", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FZ21", "url": "https://www.orthodb.org/?gene=A0A9J7FZ21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15706:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15706:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08944", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08944", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271909", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271909", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRKFTEIYEFHKMLKEMFPIEAGEINTENRIIPHLPAPRWFDGQRAAESRQGTLTEYFNTLMGLPVKISRCPHLLDFFKVRPDDLKLPTDSQVKKPETYLMPKDAKNNVADITGPIILQTYRAIADYEKSSRTEMTVATGDVVDVVEKSESGWWFCQMKTKRGWVPASYLEPLDSPDEAEDPDPNYAGEPYVTIKAYTAVEEDEVSLSEGEAIEVIHKLLDGWWVVRKGDATGYFPSMYLQKAGEEVTQAQRLIRGRGAPPRRSTIRNVQSIHQRSRKRLSQDAYRRNSVRFLQQRRRPGRPGPQSAQGSKNNLPSQHAKAQPAVPPRPSADLILHRCTESTKRKLASAV", "length": 390, "header": "tr|A0A9J7FZ21-1|A0A9J7FZ21_CRIGR Isoform 1 of Neutrophil cytosol factor 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ncf1 PE=4 SV=1 CANONICAL=A0A9J7FZ21-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZ21-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21/entry#A0A9J7FZ21-1", "sequence": { "sequence": "MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRKFTEIYEFHKMLKEMFPIEAGEINTENRIIPHLPAPRWFDGQRAAESRQGTLTEYFNTLMGLPVKISRCPHLLDFFKVRPDDLKLPTDSQVKKPETYLMPKDAKNNVADITGPIILQTYRAIADYEKSSRTEMTVATGDVVDVVEKSESGWWFCQMKTKRGWVPASYLEPLDSPDEAEDPDPNYAGEPYVTIKAYTAVEEDEVSLSEGEAIEVIHKLLDGWWVVRKGDATGYFPSMYLQKAGEEVTQAQRLIRGRGAPPRRSTIRNVQSIHQRSRKRLSQDAYRRNSVRFLQQRRRPGRPGPQSAQGSKNNLPSQHAKAQPAVPPRPSADLILHRCTESTKRKLASAV", "length": 390, "header": "tr|A0A9J7FZ21-1|A0A9J7FZ21_CRIGR Isoform 1 of Neutrophil cytosol factor 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ncf1 PE=4 SV=1 CANONICAL=A0A9J7FZ21-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769204", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769204", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "NADPH oxidase complex", "id": "GO:0043020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "reactive oxygen species biosynthetic process", "id": "GO:1903409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903409", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ], "pmid": "" }, { "name": "respiratory burst", "id": "GO:0045730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ], "pmid": "" }, { "name": "superoxide anion generation", "id": "GO:0042554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042554", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ], "pmid": "" }, { "name": "superoxide-generating NADPH oxidase activator activity", "id": "GO:0016176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016176", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FZ21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 125, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FZ21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ21" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 156, "end_pos": 215, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A9J7FZ43", "uniprot_id": "A0A9J7FZ43_CRIGR", "mass": { "chemical_mass": 105093.0, "monoisotopic_mass": 105093.0 }, "refseq": { "ac": "XP_027272635", "name": "scaffold attachment factor B1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272635" }, "gene_names": [ { "name": "Safb", "type": "recommended", "evidence": [ { "id": "A0A9J7FZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ] }, { "name": "Safb", "type": "synonym", "evidence": [ { "id": "XP_027272635", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272635" } ] } ], "protein_names": [ { "name": "Scaffold attachment factor B1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7FZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43/entry#names_and_taxonomy" } ] }, { "name": "scaffold attachment factor B1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027272635", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272635" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272635", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272635" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Safb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43", "locus": {} } ], "crossref": [ { "id": "A0A9J7FZ43", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FZ43", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12679", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12679", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771098", "url": "https://www.ncbi.nlm.nih.gov/gene/100771098", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051738", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051738", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771098", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771098", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FZ43", "url": "https://www.orthodb.org/?gene=A0A9J7FZ43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15683", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15683", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15683:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15683:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02037", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02037", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272635", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272635", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LGM3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LGM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ43-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JS50", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JS50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JS50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JS50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAETLSGLGDAGAAGAAAVSSAASETETRRLSDLRVIDLRAELKKRNLDSSGNKSVLMERLKKAIEDEGGNPDEIEVTAEGNKKMPKRPSKGKKPEDEGVEDNGLEENSGDGQEDVETSLENLQDMDMMDISVLDEADIDSGSVADCVEEEEEATLPEGLADSTELVEGDLKGLPEQLQEHAVDDKEAVNNVDTSSSDFTILQEMEEASLEPENEKILDILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEQEEEQEEEGDLALVRNSESESPSTRCQWSEAEAPLAVVKREPGEVAGAGGGPGMDREPVGLEEPVEQSSTAAQLEEATSQELVRAPTASLSPEPQDSKDDVKKFAFDACNDVPAAPKESSASEGADQKMSSVEEDSDTKRLSREEKGRSSCGRNFWVSGLSSTTRATDLKNLFSRYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCISHLHKTELHGKMISVEKAKSEPAGKRVPDRRDGDSKKEKASTSDRSANLKREEKADRKDDAKKGDDGNTEKSKDLDDQKPGPSERSRTTKSGSRGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSASREKRSVVSFDKVKESRKSRDSESRRERERSEREQRLQAQWEREERERLEIARERLAFHRHRLERERMERERLERERMHVEQERRREQERIHREREELRRQQELRYEQERRPAVRRPYDVDGRRDDAYWPEAKRAALDDRYHSDFGRQDRFHDFDHRDRGRYPNHSVDRREGSRSMMGDREGQHYPERHGGPERHGRDSRDGWGYSSNKRMSEGRGLPPPPRGRRDWGEHSRRLEDDRAWQGAADGGMMEREHKRWQGGERSMSGHSGPGHMMNRGGMSGRGSFAPGGASRGHVIPRGGMQGGFGGQSRGSRPSDARFTRRY", "length": 938, "header": "tr|A0A9J7FZ43-1|A0A9J7FZ43_CRIGR Isoform 1 of Scaffold attachment factor B1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Safb PE=4 SV=1 CANONICAL=A0A9J7FZ43-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LGM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43/entry#A0A8C2LGM3-1", "sequence": { "sequence": "MAETLSGLGDAGAAGAAAVSSAASETETRRLSDLRVIDLRAELKKRNLDSSGNKSVLMERLKKAIEDEGGNPDEIEVTAEGNKKMPKRPSKGKKPEDEGVEDNGLEENSGDGQEDVETSLENLQDMDMMDISVLDEADIDSGSVADCVEEEEEATLPEGLADSTELVEGDLKGLPEQLQEHAVDDKEAVNNVDTSSSDFTILQEMEEASLEPENEKILDILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEQEEEQEEEGDLALVRNSESESPSTRCQWSEAEAPLAVVKREPGEVAGAGGGPGMDREPVGLEEPVEQSSTAAQLEEATSQELVRAPTASLSPEPQDSKDDVKKFAFDACNDVPAAPKESSASEGADQKMSSVEEDSDTKRLSREEKGRSSCGRNFWVSGLSSTTRATDLKNLFSRYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCISHLHKTELHGKMISVEKAKSEPAGKRVPDRRDGDSKKEKASTSDRSANLKREEKADRKDDAKKGDDGNTEKSKDLDDQKPGPSERSRTTKSGSRGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSASREKRSVVSFDKVKESRKSRDSESRRERERSEREQRLQAQWEREERERLEIARERLAFHRHRLERERMERERLERERMHVEQERRREQERIHREREELRRQQELRYEQERRPAVRRPYDVDGRRDDAYWPEAKRAALDDRYHSDFGRQDRFHDFDHRDRGRYPNHSVDRREGSRSMMGDREGQHYPERHGGPERHGRDSRDGWGYSSNKRMSEGRGLPPPPRRDWGEHSRRLEDDRAWQGAADGGMMEREHKRWQGGERSMSGHSGPGHMMNRGGMSGRGSFAPGGASRGHVIPRGGMQGGFGGQSRGSRPSDARFTRRY", "length": 936, "header": "tr|A0A8C2LGM3-1|A0A8C2LGM3_CRIGR Computationally mapped isoform of Scaffold attachment factor B1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Safb PE=4 SV=1 CANONICAL=A0A9J7FZ43-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZ43-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43/entry#A0A9J7FZ43-1", "sequence": { "sequence": "MAETLSGLGDAGAAGAAAVSSAASETETRRLSDLRVIDLRAELKKRNLDSSGNKSVLMERLKKAIEDEGGNPDEIEVTAEGNKKMPKRPSKGKKPEDEGVEDNGLEENSGDGQEDVETSLENLQDMDMMDISVLDEADIDSGSVADCVEEEEEATLPEGLADSTELVEGDLKGLPEQLQEHAVDDKEAVNNVDTSSSDFTILQEMEEASLEPENEKILDILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEQEEEQEEEGDLALVRNSESESPSTRCQWSEAEAPLAVVKREPGEVAGAGGGPGMDREPVGLEEPVEQSSTAAQLEEATSQELVRAPTASLSPEPQDSKDDVKKFAFDACNDVPAAPKESSASEGADQKMSSVEEDSDTKRLSREEKGRSSCGRNFWVSGLSSTTRATDLKNLFSRYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCISHLHKTELHGKMISVEKAKSEPAGKRVPDRRDGDSKKEKASTSDRSANLKREEKADRKDDAKKGDDGNTEKSKDLDDQKPGPSERSRTTKSGSRGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSASREKRSVVSFDKVKESRKSRDSESRRERERSEREQRLQAQWEREERERLEIARERLAFHRHRLERERMERERLERERMHVEQERRREQERIHREREELRRQQELRYEQERRPAVRRPYDVDGRRDDAYWPEAKRAALDDRYHSDFGRQDRFHDFDHRDRGRYPNHSVDRREGSRSMMGDREGQHYPERHGGPERHGRDSRDGWGYSSNKRMSEGRGLPPPPRGRRDWGEHSRRLEDDRAWQGAADGGMMEREHKRWQGGERSMSGHSGPGHMMNRGGMSGRGSFAPGGASRGHVIPRGGMQGGFGGQSRGSRPSDARFTRRY", "length": 938, "header": "tr|A0A9J7FZ43-1|A0A9J7FZ43_CRIGR Isoform 1 of Scaffold attachment factor B1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Safb PE=4 SV=1 CANONICAL=A0A9J7FZ43-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JS50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43/entry#A0A9J7JS50-1", "sequence": { "sequence": "MKAGILMKLKSLLRATRRCLRGPAKVDDKEAVNNVDTSSSDFTILQEMEEASLEPENEKILDILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEQEEEQEEEGDLALVRNSESESPSTRCQWSEAEAPLAVVKREPGEVAGAGGGPGMDREPVGLEEPVEQSSTAAQLEEATSQELVRAPTASLSPEPQDSKDDVKKFAFDACNDVPAAPKESSASEGADQKMSSVEEDSDTKRLSREEKGRSSCGRNFWVSGLSSTTRATDLKNLFSRYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCISHLHKTELHGKMISVEKAKSEPAGKRVPDRRDGDSKKEKASTSDRSANLKREEKADRKDDAKKGDDGNTEKSKDLDDQKPGPSERSRTTKSGSRGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSASREKRSVVSFDKVKESRKSRDSESRRERERSEREQRLQAQWEREERERLEIARERLAFHRHRLERERMERERLERERMHVEQERRREQERIHREREELRRQQELRYEQERRPAVRRPYDVDGRRDDAYWPEAKRAALDDRYHSDFGRQDRFHDFDHRDRGRYPNHSVDRREGSRSMMGDREGQHYPERHGGPERHGRDSRDGWGYSSNKRMSEGRGLPPPPRGRRDWGEHSRRLEDDRAWQGAADGGMMEREHKRWQGGERSMSGHSGPGHMMNRGGMSGRGSFAPGGASRGHVIPRGGMQGGFGGQSRGSRPSDARFTRRY", "length": 781, "header": "tr|A0A9J7JS50-1|A0A9J7JS50_CRIGR Computationally mapped isoform of Scaffold attachment factor B1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Safb PE=4 SV=1 CANONICAL=A0A9J7FZ43-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771098", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771098", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "pmid": "" }, { "name": "regulation of androgen receptor signaling pathway", "id": "GO:0060765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060765", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "pmid": "" }, { "name": "estrogen receptor signaling pathway", "id": "GO:0030520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030520", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "pmid": "" }, { "name": "regulation of mRNA processing", "id": "GO:0050684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050684", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ43", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 427, "end_pos": 505, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ43" }, { "id": "PS50800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAP", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 65, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 53, "end_pos": 55 }, { "start_pos": 780, "end_pos": 782 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "A0A9J7FZ63-1", "uniprot_ac": "A0A9J7FZ63", "uniprot_id": "A0A9J7FZ63_CRIGR", "mass": { "chemical_mass": 117262.0, "monoisotopic_mass": 117262.0 }, "refseq": { "ac": "XP_027272668", "name": "dipeptidyl peptidase 9 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272668" }, "gene_names": [ { "name": "Dpp9", "type": "recommended", "evidence": [ { "id": "A0A9J7FZ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" } ] }, { "name": "Dpp9", "type": "synonym", "evidence": [ { "id": "XP_027272668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272668" } ] } ], "protein_names": [ { "name": "dipeptidyl-peptidase IV", "type": "recommended", "evidence": [ { "id": "A0A9J7FZ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63/entry#names_and_taxonomy" } ] }, { "name": "3.4.14.5", "type": "synonym", "evidence": [ { "id": "A0A9J7FZ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63/entry#names_and_taxonomy" } ] }, { "name": "dipeptidyl peptidase 9 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027272668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272668" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272668" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dpp9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63", "locus": {} } ], "crossref": [ { "id": "A0A9J7FZ63", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FZ63", "database": "AlphaFoldDB", "categories": [] }, { "id": "100757878", "url": "https://www.ncbi.nlm.nih.gov/gene/100757878", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002469", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002469", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757878", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757878", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VTHMTPQ", "url": "https://omabrowser.org/oma/group/VTHMTPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FZ63", "url": "https://www.orthodb.org/?gene=A0A9J7FZ63", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11731", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11731", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11731:SF109", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11731:SF109", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00930", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00930", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MQJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MQJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ63-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSLIPSQSQFITSVSPLLPVITLNPQSSASDFNPCIISPTLRVQALGPSQPLPIHSIVQPPTQAPLGAPWAITNLLSRSWDWCPGGVEYSRQFPAGSWGDRALRDTSLPSAAQGMLAAPRGWEAQLESNQVDRVRPHRRRLPPAWKVRAPRLQLPWKLLGPFRSFSLPSQESQRMSSGVSPTEQVAAGDMDDTAARFCVQKHSWDGLRNIIHGSRKSSGLIISKAPHDFQFVQKPDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGSANVLDDPKSAGVATFVIQEEFDRFTGCWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEIQTDTQGKIVSSCEKELVQPFSSLFPKVEYIARAGWTRDGRYAWAMFLDRPQQRLQLVLLPPALFIPSPENEAQRQAAARAVPKNVQPFVIYEEVTNVWINVHDIFHPFPQAEGQQDFSFLRANECKTGFCHLYKVTVELKTSDYDWTEPLSPTEDEFKCPIKEEVALTSGEWEVLSRHGSKIWVNEQTKLVYFQGTKDTPLEHHLYVVSYESAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGSDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRADVQLYGMIYKPHTLQPGRKHPTVLFVYGGPQVQLVTNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQYVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQQGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEHL", "length": 1037, "header": "tr|A0A9J7FZ63-1|A0A9J7FZ63_CRIGR Isoform 1 of dipeptidyl-peptidase IV OS=Cricetulus griseus OX=10029 GN=Dpp9 PE=3 SV=1 CANONICAL=A0A9J7FZ63-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MQJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63/entry#A0A8C2MQJ4-1", "sequence": { "sequence": "MSSGVSPTEQVAAGDMDDTAARFCVQKHSWDGLRNIIHGSRKSSGLIISKAPHDFQFVQKPDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGSANVLDDPKSAGVATFVIQEEFDRFTGCWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEIQTDTQGKIVSSCEKELVQPFSSLFPKVEYIARAGWTRDGRYAWAMFLDRPQQRLQLVLLPPALFIPSPENEAQRQAAARAVPKNVQPFVIYEEVTNVWINVHDIFHPFPQAEGQQDFSFLRANECKTGFCHLYKVTVELKTSDYDWTEPLSPTEDEFKCPIKEEVALTSGEWEVLSRHGSKIWVNEQTKLVYFQGTKDTPLEHHLYVVSYESAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGSDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRADVQLYGMIYKPHTLQPGRKHPTVLFVYGGPQVQLVTNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQYVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQQGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEHL", "length": 862, "header": "tr|A0A8C2MQJ4-1|A0A8C2MQJ4_CRIGR Computationally mapped isoform of dipeptidyl-peptidase IV OS=Cricetulus griseus OX=10029 GN=Dpp9 PE=3 SV=1 CANONICAL=A0A9J7FZ63-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZ63-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63/entry#A0A9J7FZ63-1", "sequence": { "sequence": "MPSLIPSQSQFITSVSPLLPVITLNPQSSASDFNPCIISPTLRVQALGPSQPLPIHSIVQPPTQAPLGAPWAITNLLSRSWDWCPGGVEYSRQFPAGSWGDRALRDTSLPSAAQGMLAAPRGWEAQLESNQVDRVRPHRRRLPPAWKVRAPRLQLPWKLLGPFRSFSLPSQESQRMSSGVSPTEQVAAGDMDDTAARFCVQKHSWDGLRNIIHGSRKSSGLIISKAPHDFQFVQKPDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGSANVLDDPKSAGVATFVIQEEFDRFTGCWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEIQTDTQGKIVSSCEKELVQPFSSLFPKVEYIARAGWTRDGRYAWAMFLDRPQQRLQLVLLPPALFIPSPENEAQRQAAARAVPKNVQPFVIYEEVTNVWINVHDIFHPFPQAEGQQDFSFLRANECKTGFCHLYKVTVELKTSDYDWTEPLSPTEDEFKCPIKEEVALTSGEWEVLSRHGSKIWVNEQTKLVYFQGTKDTPLEHHLYVVSYESAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGSDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRADVQLYGMIYKPHTLQPGRKHPTVLFVYGGPQVQLVTNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQYVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQQGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEHL", "length": 1037, "header": "tr|A0A9J7FZ63-1|A0A9J7FZ63_CRIGR Isoform 1 of dipeptidyl-peptidase IV OS=Cricetulus griseus OX=10029 GN=Dpp9 PE=3 SV=1 CANONICAL=A0A9J7FZ63-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757878", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757878", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QP51-1", "protein_name": "Dipeptidyl peptidase 9", "gene_name": "dpp9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYRGKRVKLEDETEGSWKSFAAVRMTAVDDISDSTEVVEMEDVPSQFFVEKHSWDGLRDIIHNSRMYSGMVINKAPHDFQFVQKHDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKIRKEALLVLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDYHAQSGLFLFQASNSLFYCRDGGHNGFIQAAPMKPMEIKTQCSGIRMDPKISPGDPSFIAFINNNDLWVTNIETAEERRLTFCHKGLNNVKEDPKSAGVATFVIQEEFDRFTGYWWSPAATEDADGGKTLQLLYEEVDESEVEIIHVPSPALEERKADVYRYPRTGSKNPQISLKLAEIRTDQQGKMISAQNKELVLPFTTLFPGVEYIARAGWTKDGKFAWAVLLDRSQQKLQLVLLPPALFIPVSVDDPQWEEHVEAMPEGVQPFIIYEEITDIWINVHDIFYPFIQTSNDKISFLWVNESQTGFCHLYRITSLLKPGCHQWSREYSPSEDDFKCSTEEEVALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYESPGEIVRLTKPGFSHSCSVSQNFDMFISHYSNVSTPPCVHVYKLTGADSDPLHKEPEFWASMMEATGCRPDYIPPEIFSFPASSGFRLYGMLYKPHNLKPGKKHPTILFVYGGPQVQLVNNSYKGVKYLRLNTLASLGYAVVVIDGRGSCQRGLKFEGALKNKMGQVEIEDQVEGLQFVAEKYKFIDLSRVAIHGWSYGGFLSLMGLIHRPNIFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQQGYEAGSVALHVDKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEIMLLYFLQQHL", "length": 885 }, "evidence": [ { "id": "A0A9J7FZ63", "url": "https://omabrowser.org/oma/group/A0A9J7FZ63/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3Q2U8J3-1", "protein_name": "dipeptidyl-peptidase IV", "gene_name": "DPP9", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQKIKRVRLENETAGSWRSFLSSSEEETMTAVDTLSDSSEVVEMEDVPSEFQVQKHSWDGLRDIIHSSRKYSGMIVNKAPHDFQFVRKTEESSPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGMYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCTGPRMDPKICPADPAFFSFINNNDLWVANIETGEEKRMTYCHKGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTSSTEGPENLKTLRILYEEVDESEVEIIHVPSPALEERKTDSYRYPRTGSKNPKITLKLAEFKADSKGKIVCAQDKELVQPFAALFPTVEYIARAGWTRDGKYAWAMFLDRPQQRLQLILLPPALFIPVPENEEQRAEFAKIVPENVQPFVIYEEITDVWINVHDIFYPFIQPEGEEEELCFIRANECKTGFCHLYRVTVVLKQGSYDWVQPYVHSEDDFKCLIKEEVALTGGEWEVLARHGSKGSTCLPGQWGWILLPCTVCSSLQTMLARKSTWASAFGNCKIWVNEATKLVYFQGTKDTPLEHHLYVVSYESPGEIVRLTIPGFSHSCSMSQNFDMFISHYSSVSTPPCVHVYKLSGSDDDPLHKQPKFWASMMEAASCPPDYVPPEIFHFRTQSDVELYGMVYKPHDVQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLYYVAEKYGFIDLSRVAIHGWSYGGFLSLMGLICKPNVFKIAIAGAPVTVWMAYDTGYTERYMDIPENNQQGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEITLLHFLQEYL", "length": 931 }, "evidence": [ { "id": "A0A9J7FZ63", "url": "https://omabrowser.org/oma/group/A0A9J7FZ63/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8I6GBE0-1", "protein_name": "dipeptidyl-peptidase IV", "gene_name": "Dpp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLGSALTLSNQKPPLPGQRRRSCRVPGVRRLRCPPAPATSGPSSWAWSVACEAPPALGTPCPACPPRRARVRTPRLQLPWKLLGPFRSFSPPSQEPQRMSGGVSPVEQVAAGDMDDTAARFCVQKHSWDGLRNIIHGSRKSSGLIVSKAPHDFQFVQKPDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNNDLWVANIETGEERRLTFCHQGSASVLDNPKSAGVATFVIQEEFDRFTGCWWCPTASWEGSGGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAELQTDHQGKIVSSCEKELVQPFSSLFPKVEYIARAGWTRDGRYAWAMFLDRPQQRLQLVLLPPALFIPTLESEAQWQEAARAIPKNVQPFIIYEEVTNVWINVHDIFHPFPQAEGQQDFCFLRANECKTGFCHLYRVTVDLKTNDYDWTEPLSPAEDEFKCPIKEEVALTSGEWEVLSRHGSKIWVNEQTKLVYFQGTKDTPLEHHLYVVSYESAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRADVQLYGMIYKPHTLQPGRKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLHFEGALKNQMGQVEIEDQVEGLQYVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQQGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCRESGEHYEVTLLHFLQEHL", "length": 961 }, "evidence": [ { "id": "A0A9J7FZ63", "url": "https://omabrowser.org/oma/group/A0A9J7FZ63/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AAA9TGY1-1", "protein_name": "dipeptidyl-peptidase IV", "gene_name": "DPP9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRKVKKLRLDNVNTGHWRSFSLNSQGAERMATGALTSERGDAAETEDPASRFQVQKHSWEGLRSIIHGSRKNSGLVVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPRKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHKGLSSVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGCKTLRILYEEVDESEVEIIHVPSPALEERKTDSYRYPRTGSKNPRIALKLAEFQTDSQGKIVSTQEKELVQPFSLLFPKVEYLARAGWTQDGKYAWAMFLDRPQQRLQLVLLPPALFIPTTDNEEQRAAFARAVPRDVQPYVVYEEVTDVWINVHDIFYPFPQAEGVDELCFIRANECKTGFCHLYKVTAVLRPRGYDWTQPFSPGDDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEVAGEIVRLTTPGFSHSCSMSQNFDMFISHYSSVGTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHAVQPGRKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQLGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEHL", "length": 891 }, "evidence": [ { "id": "A0A9J7FZ63", "url": "https://omabrowser.org/oma/group/A0A9J7FZ63/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LM79-1", "protein_name": "dipeptidyl-peptidase IV", "gene_name": "DPP9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRKVKKLRLDNANTGRWRSFSLNSEGAERMATGAPTSDRGDRGDTVEMEDPASRFQVQKHSWDELRNIIHGSRKNSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPRKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEEQRLTFCHRGLSSVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSDGCKTLRILYEEVDESEVEIIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFRTLFPKVEYIARAGWTRDGKYAWAMFLDRPQQRLQLVLLPPALFIPTTESEEQRAALARAVPRNVQPYVVYEEVTDVWINVHDIFYPFPQPEGEDELCFIRANECKTGFCHLYKVTAVLKPHGYDWTQPFNPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYETAGEIVRLTTPGFSHSCSMSQNFDMFISHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHAVQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQLGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL", "length": 894 }, "evidence": [ { "id": "A0A9J7FZ63", "url": "https://omabrowser.org/oma/group/A0A9J7FZ63/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54U01-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MESKKYKIEGRDELLDKEEILKLLGEESGSSAPYSFEFNDSKNHLYFLSNVKDQKNIKNIHYIDMNSDSKEIKPLFNYVDKDVELSIEDQLQRERMRTAANGITQFTFDQKHQFIIAPINNKINKIDIKESITKPIIKEIVGETYNHQISADGKIVSFLKDKDIWITDISTNAMYRITFSNDEKHHKFRYAGDIGFIYAEEFSRYTGYWWSPIVGTCVKTGKPMYTICYLEEDETNVMDYHIPTSDLRGKTTQYKYPLAGEKNSICKVCLVSFVLPTRTTFQDSKIEIVKSELFDLKTQFPWAEYITRAGWTPNGHSIYLQLLDRKQQHLALVMVPLHVFAEDYSSSSSSSVKSIPKLPVLIEETTSVWINIEFSFQFLKSIENQLIWSNEQSGYRHLYLIKWDKNFTNIQSTPITLSTCNDNDNDNNNWMVSSDDIHIDEKRKLVYFTGTKDTCLEQHLYVTRFDKPNSEIKRLSHANFSHRSISISSNFKKFITTYSNISTISKTEVFDLIYNDDNNDNNDIYPIVKSSFFINDDDDDDDNDKKKININIPKIFNFKNSKGVTIYGQYTLPSDYSKDKKYPTVVYVYGGPHVQIVRNQYNYIKQHYTNFGFIQVMIDNVGSANRGLEFESHIREKMGQVEIGDQVEGINYLVGNDIVSIDVNRIAISGWSYGGYNSLMAISQRPDVFKIAVCGAPVSDWRLYNTGYTERYMNVPQDNIDGYKLGDTTHYSFPTEENRLLLIHGLQDENVHFSNTIYIIDHLTKTQKPYILKTLPNERHGVRNTDNRIYIGLFVINHLLKNL", "length": 803 }, "evidence": [ { "id": "A0A9J7FZ63", "url": "https://omabrowser.org/oma/group/A0A9J7FZ63/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86TI2-1", "protein_name": "Dipeptidyl peptidase 9", "gene_name": "DPP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQKTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAASCPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPESGEHYEVTLLHFLQEYL", "length": 863 }, "evidence": [ { "id": "A0A9J7FZ63", "url": "https://omabrowser.org/oma/group/A0A9J7FZ63/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BVG4-1", "protein_name": "Dipeptidyl peptidase 9", "gene_name": "Dpp9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCSGVSPVEQVAAGDMDDTAARFCVQKHSWDGLRSIIHGSRKSSGLIVSKAPHDFQFVQKPDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGVYSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGSAGVLDNPKSAGVATFVIQEEFDRFTGCWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKLAELQTDHQGKIVSSCEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQRLQLVLLPPALFIPAVESEAQRQAAARAVPKNVQPFVIYEEVTNVWINVHDIFHPFPQAEGQQDFCFLRANECKTGFCHLYRVTVELKTKDYDWTEPLSPTEDEFKCPIKEEVALTSGEWEVLSRHGSKIWVNEQTKLVYFQGTKDTPLEHHLYVVSYESAGEIVRLTTLGFSHSCSMSQSFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAANCPPDYVPPEIFHFHTRADVQLYGMIYKPHTLQPGRKHPTVLFVYGGPQVQLVNNSFKGIKYLRLNTLASLGYAVVVIDGRGSCQRGLHFEGALKNQMGQVEIEDQVEGLQYVAEKYGFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQQGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCRESGEHYEVTLLHFLQEHL", "length": 862 }, "evidence": [ { "id": "A0A9J7FZ63", "url": "https://omabrowser.org/oma/group/A0A9J7FZ63/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FNF6-1", "protein_name": "Prolyl oligopeptidase family protein", "gene_name": "MOP9.8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADKDVPFGVEDIVQTPLPGYVAPTAVSFSPDDSLITYLFSPEKNLKRRVYAFDVNKGESNLVFSPPDGGVDESNISPEEKLRRERLRERGLGVTRYEWVKTNSKMRFIVVPLPAGVYMKDLSSSPNPELIVPSSPTSPIIDPRLSPNGLFLAYVRESELHVLNLLKNQTQQLTSGANGSTLSHGLAEYIAQEEMDRRNGYWWSLDSKFIAYTEVDSSQIPLFRIMHQGKRSVGSEAQEDHAYPFAGALNSTLRLGVVSSAGGGKTTWMNLVCGGRGNTEDEYLGRVNWLPGNVLIVQVLNRSQSKLKIISFDINTGQGNVLLTEESDTWVTLHDCFTPLEKVPSSRGSGGFIWASERTGFRHLYLYESDGTCLGAITSGEWMVEQIAGVNEPMSLVYFTGTLDGPLETNLYCAKLEAGNTSRCQPMRLTHGKGKHIVVLDHQMKNFVDIHDSVDSPPRVSLCSLSDGTVLKILYEQTSPIQILKSLKLEPPEFVQIQANDGKTTLYGAVYKPDSSKFGPPPYKTMINVYGGPSVQLVYDSWINTVDMRTQYLRSRGILVWKLDNRGTARRGLKFESWMKHNCGYVDAEDQVTGAKWLIEQGLAKPDHIGVYGWSYGGYLSATLLTRYPEIFNCAVSGAPVTSWDGYDSFYTEKYMGLPTEEERYLKSSVMHHVGNLTDKQKLMLVHGMIDENVHFRHTARLVNALVEAGKRYELLIFPDERHMPRKKKDRIYMEQRIWEFIEKNL", "length": 746 }, "evidence": [ { "id": "A0A9J7FZ63", "url": "https://omabrowser.org/oma/group/A0A9J7FZ63/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VC19-1", "protein_name": "Dipeptidyl peptidase 9", "gene_name": "Dmel\\CG3744", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MESRTQMNQSNQQQQQQRNRLPSSPSPPLSVVSLTGGPNANTTLMGLEHDAVPSSQLGRNNNNGGGHHRSHSITNAATTSLANLLDGFTARVSTAVSVAGGTNMLMDRSSQSAASTPGSTHSIASLTSMGSLGTTANALYSSIGSALNSITSPIQAAAAAATATTTEVVVAAASVITNHLSSPTSGTPPHGLDVDEGDDECDDCEEDEDDPVDNDGHIAAPTPNKSWAENKQVVQEIRKKMCNLSSMVPTNVQFRHLSDGRARCYFLGTPPQSWETTLLFADINLTQSEEQQLLVQRLEGIASDEWSPTMNAGSPTSSGHQPAFLFNSLPRPRLPWSPLLQQPIQSSGGSGGSGSASPYAREYQLLQERKRLSTWGITSYELHKPSGKLVFPCFNDLYQCLDTGYNSGLLFPTQLRTCPQWTALDPQICPQNSDMIAYISDCDLFVTHTLSGHEKRLTYTSTGRHSYVDDALSAGVPSYVMQEEFSRYQGFWWQPHSNDGIYRIVYEEVDESEVSVYTFPSSTAMHGRVDEYRFPRTGSPNAKSKLKLVQFVLNEALQVSEIAIKDLPYSLLAVFSWLEYIVRVGWTPDAKYVWVQGLDRKQQRLDVILIPLDNFCESYSSQVSTPTDSIGDHSWRSLYSRTITPLQVIYTERSDSWINVHDMLHFLDLTETSVTFLWASEETGFRHLYLVTASLLLSQANGQPDPGSVGAQPSFVDLSALQPRILNKVALTSGEWEVLARNLWVDKANKLVYFVGLRDTPLEKHLYVVSLERPEHIRLLTEPGYSYLVEFDDQCKLMLLVYCNIQRLPSCKVMRVNQTCSNGGVNGIQISLVGYLHEGGKPEPQYCPQIFSPQLPSGDIVYAMVFKPHNFELGVKYPTVLNVYGGPEVQTVNNTFKGKHQLRMHMLAAQGYCVICIDSRGSRHRGKRFESHIRGRMGQVELTDQVDALRSLSDQLGYIDMDRVAIHGWSYGGYLSLMGLVQYPKIFKVAIAGAPVTNWEYYDTGYTERYMDMPQNNEAGYSAGSVLEYVNSFPEEDKRLLLIHGLIDENVHFCHTSRLISALNKANKPYEVHLFPEERHSLRNLESNKNYETKLLSFLQNL", "length": 1102 }, "evidence": [ { "id": "A0A9J7FZ63", "url": "https://omabrowser.org/oma/group/A0A9J7FZ63/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "dipeptidyl-peptidase activity", "id": "GO:0008239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008239", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" } ], "pmid": "" }, { "name": "aminopeptidase activity", "id": "GO:0004177", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004177", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" } ], "pmid": "" }, { "name": "serine-type peptidase activity", "id": "GO:0008236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008236", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZ63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FZ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" }, { "id": "PF19520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dipeptidyl peptidase 8 /9 ,N-terminal", "eco_id": "ECO_0000259", "start_pos": 194, "end_pos": 309, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FZ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" }, { "id": "PF00930", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00930" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dipeptidylpeptidase IV N-terminal", "eco_id": "ECO_0000259", "start_pos": 320, "end_pos": 744, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FZ63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ63" }, { "id": "PF00326", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S9 prolyl oligopeptidase catalytic", "eco_id": "ECO_0000259", "start_pos": 837, "end_pos": 1037, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.14.5", "ec_name": "Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.", "evidence": [ { "id": "3.4.14.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.14.5" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 379, "end_pos": 381 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FZA0-1", "uniprot_ac": "A0A9J7FZA0", "uniprot_id": "A0A9J7FZA0_CRIGR", "mass": { "chemical_mass": 130333.0, "monoisotopic_mass": 130333.0 }, "refseq": { "ac": "XP_003504786", "name": "NEDD4-binding protein 2-like 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504786" }, "gene_names": [ { "name": "N4bp2l2", "type": "recommended", "evidence": [ { "id": "A0A9J7FZA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA0" } ] }, { "name": "N4bp2l2", "type": "synonym", "evidence": [ { "id": "XP_003504786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504786" } ] } ], "protein_names": [ { "name": "NEDD4-binding protein 2-like 2", "type": "recommended", "evidence": [ { "id": "A0A9J7FZA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA0/entry#names_and_taxonomy" } ] }, { "name": "NEDD4-binding protein 2-like 2", "type": "synonym", "evidence": [ { "id": "XP_003504786", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504786" } ] }, { "name": "Phosphonoformate immuno-associated protein 5 homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7FZA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614084.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003504786.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504786" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "N4bp2l2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA0", "locus": {} } ], "crossref": [ { "id": "A0A9J7FZA0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FZA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100758949", "url": "https://www.ncbi.nlm.nih.gov/gene/100758949", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758949", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758949", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FZA0", "url": "https://www.orthodb.org/?gene=A0A9J7FZA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13308:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13308:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13671", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13671", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504786", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504786", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FZA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"https://www.ebi.ac.uk/interpro/entry/IPR029045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753124", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FZK6", "url": "https://www.orthodb.org/?gene=A0A9J7FZK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45728", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45728", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45728:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45728:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00289", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00289", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00364", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00364", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02785", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02785", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02786", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02786", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08326", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08326", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21385", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21385", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271788", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271788", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11308", "url": "https://www.rhea-db.org/rhea/11308", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FZK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLLLFLTCLVFSCLTFSWLKIWGTMTDSEPPTKSEVEASLFSSEETFPASDRSGEPLQKHGDCSSLSKTTDQEEPASHRGPRDASWQKNALPPSHQKPPRNPLSSNDTWPSPELQDPKVPDTNGSSFPARPPGQQAKSPSREDKKQAHIKRQLMTNFILGSFDDNSSDEDPIAGSFRDSPRKGSRPSLGTLSLEAALNSSDPPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWTEDSRQQGKCISVPEDVYERGCVKDVDEGLEAAKKVGFPLMIKASEGGGGKGIRKAESAEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQCAVLLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFENPLNLPSARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAERVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGIKYILKVARQSPTMFVLIMNNCHIEIDVHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGDHVEAGSSYAEMEVMKMIMTLSVQESGRVRYVKRPGVVLEAGCVVARLELDDASKVHAAQPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGYCLPEPFFSTKLKEWVQKLMMTLRHPTLPLLELQEIMTSVAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRRYLNVEHYFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPALSDELTSILNELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHENKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFRFMLPSSHPNRMAIPISISNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFANMPTDAPLFSKARTSLYSDDGKNLREEPIHILNVAIQCADHLEDEALVPIFRTFVQSKKNILVDYGLRRITFLIAREREFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPLKIEESVRAMVMRYGSRLWKLRVLQAEVKINIRETTTGSAIPIRLFITNESGYYLDISVYKEVTDSRSGNIMFQSFGNKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPEKYPKDILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTPEYPEGRDVIVISNDITFQIGSFGIEEDFLYLRASEMARTEGIPQIFLAANSGARMGLAEEIKQIFQVAWVDPDDPHKGFRYLYLTPQDYTQISAHNAVHCKHIEDGGESRYVIMDVIGKSGNLGVENLRGSGMIAGEASLAYEKIVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMHMNGVSHVTVPDDFEGVCTILEWLSYIPKDNRSPVPIITPTDPIDREIEFVPSKAPYDPRWLLAGRPHPTLKGSWQSGFFDHGSFTEIMAPWAQTVVTGRARLGGIPLGVIAVETRSVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIRDFNQEHLPLMIFANWRGFSGGMKDMYEQMLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVLDSTINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLVKTMRRLDPVCKKLVGQLGTAQLPDKDRKELEGQLKAREDLLFPIYHQVAVQFADLHDTPGHMLEKGIILDVLEWKTARTFFYWRLRRLLLEAQVKQEILQASPELSHEHTQSMLRRWFVETEGPVKAYLWDSNQVVVQWLEQHWSAGGGLRSTIRENINYLKRDSVLKTIQSLVQGNPDVTMDCVAYLSQHLTPAERIQVAQLLSTTESPASS", "length": 2446, "header": "tr|A0A9J7FZK6-1|A0A9J7FZK6_CRIGR Isoform 1 of acetyl-CoA carboxylase OS=Cricetulus griseus OX=10029 GN=Acacb PE=4 SV=1 CANONICAL=A0A9J7FZK6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6/entry#A0A9J7FZK6-1", "sequence": { "sequence": "MVLLLFLTCLVFSCLTFSWLKIWGTMTDSEPPTKSEVEASLFSSEETFPASDRSGEPLQKHGDCSSLSKTTDQEEPASHRGPRDASWQKNALPPSHQKPPRNPLSSNDTWPSPELQDPKVPDTNGSSFPARPPGQQAKSPSREDKKQAHIKRQLMTNFILGSFDDNSSDEDPIAGSFRDSPRKGSRPSLGTLSLEAALNSSDPPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLCKHEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWTEDSRQQGKCISVPEDVYERGCVKDVDEGLEAAKKVGFPLMIKASEGGGGKGIRKAESAEDFPMLFRQVQSEIPGSPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAAPAVFEFMEQCAVLLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFENPLNLPSARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAERVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGIKYILKVARQSPTMFVLIMNNCHIEIDVHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGDHVEAGSSYAEMEVMKMIMTLSVQESGRVRYVKRPGVVLEAGCVVARLELDDASKVHAAQPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGYCLPEPFFSTKLKEWVQKLMMTLRHPTLPLLELQEIMTSVAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRRYLNVEHYFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPALSDELTSILNELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHENKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFRFMLPSSHPNRMAIPISISNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEEFTRNFDEVISCFANMPTDAPLFSKARTSLYSDDGKNLREEPIHILNVAIQCADHLEDEALVPIFRTFVQSKKNILVDYGLRRITFLIAREREFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPLKIEESVRAMVMRYGSRLWKLRVLQAEVKINIRETTTGSAIPIRLFITNESGYYLDISVYKEVTDSRSGNIMFQSFGNKQGSLHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPEKYPKDILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTPEYPEGRDVIVISNDITFQIGSFGIEEDFLYLRASEMARTEGIPQIFLAANSGARMGLAEEIKQIFQVAWVDPDDPHKGFRYLYLTPQDYTQISAHNAVHCKHIEDGGESRYVIMDVIGKSGNLGVENLRGSGMIAGEASLAYEKIVTISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMHMNGVSHVTVPDDFEGVCTILEWLSYIPKDNRSPVPIITPTDPIDREIEFVPSKAPYDPRWLLAGRPHPTLKGSWQSGFFDHGSFTEIMAPWAQTVVTGRARLGGIPLGVIAVETRSVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQVIRDFNQEHLPLMIFANWRGFSGGMKDMYEQMLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVLDSTINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLVKTMRRLDPVCKKLVGQLGTAQLPDKDRKELEGQLKAREDLLFPIYHQVAVQFADLHDTPGHMLEKGIILDVLEWKTARTFFYWRLRRLLLEAQVKQEILQASPELSHEHTQSMLRRWFVETEGPVKAYLWDSNQVVVQWLEQHWSAGGGLRSTIRENINYLKRDSVLKTIQSLVQGNPDVTMDCVAYLSQHLTPAERIQVAQLLSTTESPASS", "length": 2446, "header": "tr|A0A9J7FZK6-1|A0A9J7FZK6_CRIGR Isoform 1 of acetyl-CoA carboxylase OS=Cricetulus griseus OX=10029 GN=Acacb PE=4 SV=1 CANONICAL=A0A9J7FZK6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753124", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" } ], "pmid": "" }, { "name": "acetyl-CoA carboxylase activity", "id": "GO:0003989", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003989", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid biosynthetic process", "id": "GO:0006633", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006633", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1060, "end_pos": 1062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1569, "end_pos": 1571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1570, "end_pos": 1572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1641, "end_pos": 1643, "annotation": "n_glycosylation_sequon" }, { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2005, "end_pos": 2007, "annotation": "n_glycosylation_sequon" }, { "start_pos": 851, "end_pos": 853, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" }, { "start_pos": 991, "end_pos": 993, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11308", "name": "", "equation": "hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7FZK6-1" ], "evidence": [ { "id": "11308", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11308" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7FZK6", "gene_name": "Acacb", "activity": [ { "ec_number": "6.4.1.2", "activity": "hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FZK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" } ] }, { "ec_number": "6.4.1.2", "activity": "", "evidence": [ { "id": "A0A9J7FZK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FZK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" }, { "id": "PS50975", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50975" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ATP-grasp", "eco_id": "ECO_0000259", "start_pos": 407, "end_pos": 598, "start_aa": "Gln", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FZK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" }, { "id": "PS50979", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50979" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Biotin carboxylation", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 750, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FZK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZK6" }, { "id": "PS50989", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50989" } 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G092-1", "uniprot_ac": "A0A9J7G092", "uniprot_id": "A0A9J7G092_CRIGR", "mass": { "chemical_mass": 149886.0, "monoisotopic_mass": 149886.0 }, "refseq": { "ac": "XP_027273031", "name": "SUN domain-containing ossification factor isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273031" }, "gene_names": [ { "name": "Suco", "type": "recommended", "evidence": [ { "id": "A0A9J7G092", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092" } ] }, { "name": "Suco", "type": "synonym", "evidence": [ { "id": "XP_027273031", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273031" } ] } ], "protein_names": [ { "name": "SUN domain-containing ossification factor", "type": "recommended", "evidence": [ { "id": "A0A9J7G092", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092/entry#names_and_taxonomy" } ] }, { "name": "Membrane protein CH1", "type": "synonym", "evidence": [ { "id": "A0A9J7G092", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092/entry#names_and_taxonomy" } ] }, { "name": "SUN domain-containing ossification factor isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027273031", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273031" } ] }, { "name": "SUN-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7G092", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273031" } ] }, { "annotation": "Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZL6#function" }, { "database": "UniProtKB", "id": "ARBA00055064", "url": "https://www.uniprot.org/uniprotkb/ARBA00055064#function" }, { "database": "UniProtKB", "id": "A0A9J7G092", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092#function" }, { "database": "UniProtKB", "id": "A0A9J7G0Z3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Z3#function" }, { "database": "UniProtKB", "id": "A0A9J7G3T2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3T2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G092", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Suco", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092", "locus": {} } ], "crossref": [ { "id": "100753995", "url": "https://www.ncbi.nlm.nih.gov/gene/100753995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753995", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753995", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G092", "url": "https://www.orthodb.org/?gene=A0A9J7G092", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12953", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12953", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12953:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12953:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07738", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07738", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273031", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273031", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FZL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G092", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G092-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0Z3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3T2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3T2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLWRRRPRRRARRAADTAAAAAVPGAPCEGYLSALPWACRGGRPGGEPLRSRSSSATALRTLGPILALLLRLLHLGLGSGCCGEDVPPPGRGKKEEKMKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTSYYSQDDNCALESEDTQFQKKNEREEPSNAELSGKLNSYLPIPPEENKVKDDYAVDVQNMETTKLNLPVVEALPTVDLHEDSSSVVVGSENIENSSSSSTSETTPVSKLDEIEKSGTLSLAKPGETEQSEADCDAGEAPDADTPVEQHAFVSPPESLVGQHIENVSSSHGKEKVTKSEFESKVSVSGQDGDDPKSGLNASDSLKNKSSDYADYKKPGETDPAPITGPKDPEDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERTVQSFPLDEQMYAKYVKMFIKYIKVELVSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATTAPKMPESTGVSTPVPSPEYVINEVRTRDTDPSTSDTPKESPIVQLVQEEEEEASQSTVTLLGSGEQEDESSSWFESETQILCSELTSICCISSFSEYIYKWCSVRIALYRQRSRTAMSKGKEFVSAQPSLLLPVESVEVSLSQPPSGDVDNENMEREAETVVLDDLSSVHQGDLMNHTVDAIEIEPSHPQSLSQSLLLDITPEMNSLPKVEGSESVKYERGHTPLQVMPQESSVESDDEMGKKPESFSSVEKPSVIYETSKVNEIVDSAVKEDISSIEIITKVSETVPPPLNTAIVPDSEDGETKMSIADTPKQTVTPVMDPSLPEVKEEDQSPEDALLRGLQRTATDFYAELQNSTDLGYGNGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIHLLQAQLTNMTQLVSNLSTTVTELKREVSDRQSYLVMSLILCVILGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKTEKIETIKPADPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQTQKTKTEKRALKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI", "length": 1352, "header": "tr|A0A9J7G092-1|A0A9J7G092_CRIGR Isoform 1 of SUN domain-containing ossification factor OS=Cricetulus griseus OX=10029 GN=Suco PE=4 SV=1 CANONICAL=A0A9J7G092-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092/entry#A0A9J7FZL6-1", "sequence": { "sequence": "MARLWRRRPRRRARRAADTAAAAAVPGAPCEGYLSALPWACRGGRPGGEPLRSRSSSATALRTLGPILALLLRLLHLGLGSGCCGEDVPPPGRGKKEEKMKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTSYYSQDDNCALESEDTQFQKKNEREEPSNAELSGKLNSYLPIPPEENKVKDDYAVDVQNMETTKLNLPVVEALPTVDLHEDSSSVVVGSENIENSSSSSTSETTPVSKLDEIEKSGTLSLAKPGETEQSEADCDAGEAPDADTPVEQHAFVSPPESLVGQHIENVSSSHGKEKVTKSEFESKVSVSGQDGDDPKSGLNASDSLKNKSSDYADYKKPGETDPAPITGPKDPEDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERTVQSFPLDEQMYAKYVKVELVSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATTAPKMPESTGVSTPVPSPEYVINEVRTRDTDPSTSDTPKESPIVQLVQEEEEEASQSTVTLLGSGEQEDESSSWFESETQILCSELTSICCISSFSEYIYKWCSVRIALYRQRSRTAMSKGKEFVSAQPSLLLPVESVEVSLSQPPSGDVDNENMEREAETVVLDDLSSVHQGDLMNHTVDAIEIEPSHPQSLSQSLLLDITPEMNSLPKVEGSESVKYERGHTPLQVMPQESSVESDDEMGKKPESFSSVEKPSVIYETSKVNEIVDSAVKEDISSIEIITKVSETVPPPLNTAIVPDSEDGETKMSIADTPKQTVTPVMDPSLPEVKEEDQSPEDALLRGLQRTATDFYAELQNSTDLGYGNGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIHLLQAQLTNMTQLVSNLSTTVTELKREVSDRQSYLVMSLILCVILGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKTEKIETIKPADPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQTQKTKTEKRALKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI", "length": 1345, "header": "tr|A0A9J7FZL6-1|A0A9J7G092_CRIGR Computationally mapped isoform of SUN domain-containing ossification factor OS=Cricetulus griseus OX=10029 GN=Suco PE=4 SV=1 CANONICAL=A0A9J7G092-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G092-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092/entry#A0A9J7G092-1", "sequence": { "sequence": "MARLWRRRPRRRARRAADTAAAAAVPGAPCEGYLSALPWACRGGRPGGEPLRSRSSSATALRTLGPILALLLRLLHLGLGSGCCGEDVPPPGRGKKEEKMKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTSYYSQDDNCALESEDTQFQKKNEREEPSNAELSGKLNSYLPIPPEENKVKDDYAVDVQNMETTKLNLPVVEALPTVDLHEDSSSVVVGSENIENSSSSSTSETTPVSKLDEIEKSGTLSLAKPGETEQSEADCDAGEAPDADTPVEQHAFVSPPESLVGQHIENVSSSHGKEKVTKSEFESKVSVSGQDGDDPKSGLNASDSLKNKSSDYADYKKPGETDPAPITGPKDPEDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERTVQSFPLDEQMYAKYVKMFIKYIKVELVSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATTAPKMPESTGVSTPVPSPEYVINEVRTRDTDPSTSDTPKESPIVQLVQEEEEEASQSTVTLLGSGEQEDESSSWFESETQILCSELTSICCISSFSEYIYKWCSVRIALYRQRSRTAMSKGKEFVSAQPSLLLPVESVEVSLSQPPSGDVDNENMEREAETVVLDDLSSVHQGDLMNHTVDAIEIEPSHPQSLSQSLLLDITPEMNSLPKVEGSESVKYERGHTPLQVMPQESSVESDDEMGKKPESFSSVEKPSVIYETSKVNEIVDSAVKEDISSIEIITKVSETVPPPLNTAIVPDSEDGETKMSIADTPKQTVTPVMDPSLPEVKEEDQSPEDALLRGLQRTATDFYAELQNSTDLGYGNGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIHLLQAQLTNMTQLVSNLSTTVTELKREVSDRQSYLVMSLILCVILGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKEVDPNDLYIVEPLKFSPEKKKKRCKYKTEKIETIKPADPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQTQKTKTEKRALKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI", "length": 1352, "header": "tr|A0A9J7G092-1|A0A9J7G092_CRIGR Isoform 1 of SUN domain-containing ossification factor OS=Cricetulus griseus OX=10029 GN=Suco PE=4 SV=1 CANONICAL=A0A9J7G092-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G0Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092/entry#A0A9J7G0Z3-1", "sequence": { "sequence": "MARLWRRRPRRRARRAADTAAAAAVPGAPCEGYLSALPWACRGGRPGGEPLRSRSSSATALRTLGPILALLLRLLHLGLGSGCCGEDVPPPGRGKKEEKMKKYRRALALVSCLSLCSLVWLPSWHVCCKESSSASTSYYSQDDNCALESEDTQFQKKNEREEPSNAELSGKLNSYLPIPPEENKVKDDYAVDVQNMETTKLNLPVVEALPTVDLHEDSSSVVVGSENIENSSSSSTSETTPVSKLDEIEKSGTLSLAKPGETEQSEADCDAGEAPDADTPVEQHAFVSPPESLVGQHIENVSSSHGKEKVTKSEFESKVSVSGQDGDDPKSGLNASDSLKNKSSDYADYKKPGETDPAPITGPKDPEDIPTFDEWKKKVMEVEKEKSQSLHPSSNGGPHATKKVQKNRNNYASVECGAKILAANPEAKSTSAILIENMDLYMLNPCSTKIWFVIELCEPIQVKQFDIANYELFSSTPKDFLVSISDRYPTNKWIKLGTFHGRDERTVQSFPLDEQMYAKYVKMFIKYIKVELVSHFGSEHFCPLSLIRVFGTSMVEEYEEIADSQYQSERQELFDEDYDYPLDYNTVEDKSSKNLLGSATNAILNMVNIAANILGAKTEDLTEGNKSISENATATTAPKMPESTGVSTPVPSPEYVINEVRTRDTDPSTSDTPKESPIVQLVQEEEEEASQSTVTLLGSGEQEDESSSWFESETQILCSELTSICCISSFSEYIYKWCSVRIALYRQRSRTAMSKGKEFVSAQPSLLLPVESVEVSLSQPPSGDVDNENMEREAETVVLDDLSSVHQGDLMNHTVDAIEIEPSHPQSLSQSLLLDITPEMNSLPKVEGSESVKYERGHTPLQVMPQESSVESDDEMGKKPESFSSVEKPSVIYETSKVNEIVDSAVKEDISSIEIITKVSETVPPPLNTAIVPDSEDGETKMSIADTPKQTVTPVMDPSLPEVKEEDQSPEDALLRGLQRTATDFYAELQNSTDLGYGNGNLVHGSNQKESVFMRLNNRIKALEVNMSLSGRYLEELSQRYRKQMEEMQKAFNKTIVKLQNTSRIAEEQDQRQTEAIHLLQAQLTNMTQLVSNLSTTVTELKREVSDRQSYLVMSLILCVILGLMLCMQRCRNTSQFDGDYISKLPKSNQYPSPKRCFSSYDDMNLKRRTSFPLIRSKSLQFTGKEDPNDLYIVEPLKFSPEKKKKRCKYKTEKIETIKPADPLHPIANGDIKGRKPFTNQRDFSNMGEVYHSSYKGPPSEGSSETSSQSEESYFCGISACTSLCNGQTQKTKTEKRALKRRRSKVQDQGKLIKALIQTKSGSLPSLHDIIKGNKEITVGAFGVTAVSGHI", "length": 1351, "header": "tr|A0A9J7G0Z3-1|A0A9J7G0Z3_CRIGR Computationally mapped isoform of SUN domain-containing ossification factor OS=Cricetulus griseus OX=10029 GN=Suco PE=4 SV=1 CANONICAL=A0A9J7G092-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G092/entry#A0A9J7G3T2-1", "sequence": { "sequence": 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"length": 1190, "header": "tr|A0A9J7G3T2-1|A0A9J7G3T2_CRIGR Computationally mapped isoform of SUN domain-containing ossification factor OS=Cricetulus griseus OX=10029 GN=Suco PE=4 SV=1 CANONICAL=A0A9J7G092-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"XP_027272388", "name": "serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272388" }, "gene_names": [ { "name": "Ppp2r5c", "type": "recommended", "evidence": [ { "id": "A0A9J7G1R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8" } ] }, { "name": "Ppp2r5c", "type": "synonym", "evidence": [ { "id": "XP_027272388", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272388" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit", "type": "recommended", "evidence": [ { "id": "A0A9J7G1R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X7", "type": "synonym", "evidence": [ { "id": "XP_027272388", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272388" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272388", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272388" } ] }, { "annotation": "The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZN1#function" }, { "database": "UniProtKB", "id": "PIRNR028043", "url": "https://www.uniprot.org/uniprotkb/PIRNR028043#function" }, { "database": "UniProtKB", "id": "A0A9J7FZV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZV4#function" }, { "database": "UniProtKB", "id": "A0A9J7FZV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZV8#function" }, { "database": "UniProtKB", "id": "A0A9J7G1R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8#function" }, { 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"url": "https://www.ncbi.nlm.nih.gov/gene/100754775", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002554", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002554", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754775", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754775", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G1R8", "url": "https://www.orthodb.org/?gene=A0A9J7G1R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10257:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10257:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01603", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01603", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272388", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272388", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I3D4", "url": "https://www.uniprot.org/uniprotkb/A0A061I3D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I3D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1S4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNI8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNKNKKEKEPPKPVKSGKGSKEGQEAAEAEIASRKNSLVAVQSSTSAKIKVPVPQPVVPVKKDKRQNSSRFNASNNRELQKLPSLKDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASAMSIPVAMETDGPQFEDVQMLRKTVSDETRQAHKDLKKDRPLVRRKSELPQDPHTEKALEAHCRASELLSQDGR", "length": 580, "header": "tr|A0A9J7G1R8-1|A0A9J7G1R8_CRIGR Isoform 1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp2r5c PE=3 SV=1 CANONICAL=A0A9J7G1R8-1" }, "isoforms": [ { "isoform_ac": "A0A061I3D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8/entry#A0A061I3D4-1", "sequence": { "sequence": "MLTCNKAGSGMVVDAASSNGPFQPVALLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASAMSIPVAMETDGPQFEDVQMLRKTVSDETRQAHKDLKKDRPLVRRKSELPQDPHTEKALEAHCRASELLSQDGR", "length": 524, "header": "tr|A0A061I3D4-1|A0A061I3D4_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp2r5c PE=3 SV=1 CANONICAL=A0A9J7G1R8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8/entry#A0A9J7FZN1-1", "sequence": { "sequence": "MLTCNKAGSGMVVDAASSNGPFQPVALLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQAHKDLKKDRPLVRRKSELPQDPHTEKALEAHCRASELLSQDGR", "length": 485, "header": "tr|A0A9J7FZN1-1|A0A9J7G1R8_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp2r5c PE=3 SV=1 CANONICAL=A0A9J7G1R8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8/entry#A0A9J7FZV4-1", "sequence": { "sequence": "MPNKNKKEKEPPKPVKSGKGSKEGQEAAEAEIASRKNSLVAVQSSTSAKIKVPVPQPVVPVKKDKRQNSSRFNASNNRELQKLPSLKDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASAMSIPVAMETDGPQFEDVQMLRKTVSDETRQ", "length": 537, "header": "tr|A0A9J7FZV4-1|A0A9J7FZV4_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp2r5c PE=3 SV=1 CANONICAL=A0A9J7G1R8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8/entry#A0A9J7FZV8-1", "sequence": { "sequence": "MLTCNKAGSGMVVDAASSNGPFQPVALLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASAMSIPVAMETDGPQFEDVQMLRKTVSDETRQVKGTQRPEEGPSPCAPQVRAASGPPHRESLGSSLQSQ", "length": 518, "header": "tr|A0A9J7FZV8-1|A0A9J7FZV8_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp2r5c PE=3 SV=1 CANONICAL=A0A9J7G1R8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8/entry#A0A9J7G1R8-1", "sequence": { "sequence": "MPNKNKKEKEPPKPVKSGKGSKEGQEAAEAEIASRKNSLVAVQSSTSAKIKVPVPQPVVPVKKDKRQNSSRFNASNNRELQKLPSLKDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASAMSIPVAMETDGPQFEDVQMLRKTVSDETRQAHKDLKKDRPLVRRKSELPQDPHTEKALEAHCRASELLSQDGR", "length": 580, "header": "tr|A0A9J7G1R8-1|A0A9J7G1R8_CRIGR Isoform 1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp2r5c PE=3 SV=1 CANONICAL=A0A9J7G1R8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8/entry#A0A9J7G1S4-1", "sequence": { "sequence": "MPNKNKKEKEPPKPVKSGKGSKEGQEAAEAEIASRKNSLVAVQSSTSAKIKVPVPQPVVPVKKDKRQNSSRFNASNNRELQKLPSLKDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQAHKDLKKDRPLVRRKSELPQDPHTEKALEAHCRASELLSQDGR", "length": 541, "header": "tr|A0A9J7G1S4-1|A0A9J7G1S4_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp2r5c PE=3 SV=1 CANONICAL=A0A9J7G1R8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8/entry#A0A9J7JNI8-1", "sequence": { "sequence": "MVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQYAVYSQASAMSIPVAMETDGPQFEDVQMLRKTVSDETRQAHKDLKKDRPLVRRKSELPQDPHTEKALEAHCRASELLSQDGR", "length": 449, "header": "tr|A0A9J7JNI8-1|A0A9J7JNI8_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp2r5c PE=3 SV=1 CANONICAL=A0A9J7G1R8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZN1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZN1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754775", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754775", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8" } ], "pmid": "" }, { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8" } ], "pmid": "" }, { "name": "chromosome, centromeric region", "id": "GO:0000775", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000775", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R8" } ], "pmid": "" }, { "name": "negative regulation of cell cycle process", "id": "GO:0010948", "url": 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7FZN9-1", "uniprot_ac": "A0A9J7FZN9", "uniprot_id": "A0A9J7FZN9_CRIGR", "mass": { "chemical_mass": 34874.0, "monoisotopic_mass": 34874.0 }, "refseq": { "ac": "XP_027269049", "name": "olfactory receptor 5AC1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269049" }, "gene_names": [ { "name": "LOC100751186", "type": "recommended", "evidence": [ { "id": "A0A9J7FZN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZN9" } ] }, { "name": "LOC100751186", "type": "synonym", "evidence": [ { "id": "XP_027269049", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269049" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7FZN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZN9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 5AC1-like", "type": "synonym", "evidence": [ { "id": "XP_027269049", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269049" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. 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Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"name": "tyrosine-protein phosphatase non-receptor type 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003497982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497982" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613669.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497982" } ] }, { "annotation": "Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZS5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5#function" }, { "database": "UniProtKB", "id": "ARBA00055430", "url": "https://www.uniprot.org/uniprotkb/ARBA00055430#function" }, { "database": "UniProtKB", "id": "A0A9J7FZT1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZT1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZS5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptpn9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5", "locus": {} } ], "crossref": [ { "id": "A0A9J7FZS5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7FZS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14543", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14543", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765899", "url": "https://www.ncbi.nlm.nih.gov/gene/100765899", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": 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Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765899", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765899", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FZS5", "url": "https://www.orthodb.org/?gene=A0A9J7FZS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19134:SF285", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19134:SF285", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00650", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00650", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FZS5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZT1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXC5", "url": 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OS=Cricetulus griseus OX=10029 GN=Ptpn9 PE=3 SV=1 CANONICAL=A0A9J7FZS5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5/entry#A0A9J7FZS5-1", "sequence": { "sequence": "MQGLVQAKPGGIVPVLKAKNNILTSRGTEATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHAYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEITQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALHWDSVHVPGPHAMTIQELVDYVNTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRVRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQRQAVSSLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVPSGHSLLATEGQ", "length": 601, "header": "tr|A0A9J7FZS5-1|A0A9J7FZS5_CRIGR Isoform 1 of Tyrosine-protein phosphatase non-receptor type 9 OS=Cricetulus griseus OX=10029 GN=Ptpn9 PE=3 SV=1 CANONICAL=A0A9J7FZS5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5/entry#A0A9J7FZT1-1", "sequence": { "sequence": "MAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHAYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEITQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALHWDSVHVPGPHAMTIQELVDYVNTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRVRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQRQAVSSLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVPSGHSLLATEGQ", "length": 583, "header": "tr|A0A9J7FZT1-1|A0A9J7FZT1_CRIGR Computationally mapped isoform of Tyrosine-protein phosphatase non-receptor type 9 OS=Cricetulus griseus OX=10029 GN=Ptpn9 PE=3 SV=1 CANONICAL=A0A9J7FZS5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5/entry#A0A9J7GXC5-1", "sequence": { "sequence": "MQGLVQAKPGGIVPVLKAKNNILTSRGTEATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHAYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKIQILKTSEITQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALHWDSVHVPGPHAMTIQELVDYVNTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRVRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQRQAVSSLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVPSGHSLLATEGQ", "length": 564, "header": "tr|A0A9J7GXC5-1|A0A9J7GXC5_CRIGR Computationally mapped isoform of protein-tyrosine-phosphatase OS=Cricetulus griseus OX=10029 GN=Ptpn9 PE=4 SV=1 CANONICAL=A0A9J7FZS5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZS5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZS5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765899", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765899", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZS5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZS5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7FZS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 251, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FZS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 489, "end_pos": 573, "start_aa": "Ile", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7FZS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS5" }, { "id": "PS50055", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50055" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 311, "end_pos": 582, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "O-phospho-L-tyrosyl-[protein] + H2O = 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11976", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11979", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11979", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20867", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20867", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21262", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21262", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765426", "url": "https://www.ncbi.nlm.nih.gov/gene/100765426", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022613", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022613", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035730", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035730", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765426", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765426", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PYISRPT", "url": "https://omabrowser.org/oma/group/PYISRPT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FZX3", "url": "https://www.orthodb.org/?gene=A0A9J7FZX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45818:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45818:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11971", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11971", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501828", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FZX3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYR5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K649", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K649", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K649-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K649-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTDDSAMGDEDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEIYEDLMRSESVSTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIHQHFMKPLQRFLKPQEIETIFVNIEELLSVHTHFLKELKDALAAPGAAMLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKIASVERRSKTDRYAFLLDKALLICKRRGDSYDLKVSVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRAPAHKECLGRVPPCGRHGQDFSGTVKKDKLHRRAQEKKRNELGLPKMEVFQEYYGIPPPPGAFGTFLRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVRPYVHGPPQDLSMHIWYAGPMERAGAEGILINRSDGTYLVRQRVKDTEEFAISIKYNVEVKHIKIMTSEGLYRITEKKAFRGLQELVEFYQQNSLKDCFKSLDTTLQFPYKEPERRAISKPPAGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYC", "length": 845, "header": "tr|A0A9J7FZX3-1|A0A9J7FZX3_CRIGR Isoform 1 of Proto-oncogene vav OS=Cricetulus griseus OX=10029 GN=Vav1 PE=4 SV=1 CANONICAL=A0A9J7FZX3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZX3/entry#A0A9J7FZX3-1", "sequence": { "sequence": "MELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTDDSAMGDEDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEIYEDLMRSESVSTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIHQHFMKPLQRFLKPQEIETIFVNIEELLSVHTHFLKELKDALAAPGAAMLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKIASVERRSKTDRYAFLLDKALLICKRRGDSYDLKVSVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRAPAHKECLGRVPPCGRHGQDFSGTVKKDKLHRRAQEKKRNELGLPKMEVFQEYYGIPPPPGAFGTFLRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVRPYVHGPPQDLSMHIWYAGPMERAGAEGILINRSDGTYLVRQRVKDTEEFAISIKYNVEVKHIKIMTSEGLYRITEKKAFRGLQELVEFYQQNSLKDCFKSLDTTLQFPYKEPERRAISKPPAGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYC", "length": 845, "header": "tr|A0A9J7FZX3-1|A0A9J7FZX3_CRIGR Isoform 1 of Proto-oncogene vav OS=Cricetulus griseus OX=10029 GN=Vav1 PE=4 SV=1 CANONICAL=A0A9J7FZX3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H0F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZX3/entry#A0A9J7H0F4-1", "sequence": { "sequence": "MELWRQCTHWLIQCRVLPPSHRVTWEGAQVSINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTDDSAMGDEDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEIYEDLMRSESVSTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIHQHFMKPLQRFLKPQEIETIFVNIEELLSVHTHFLKELKDALAAPGAAMLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKIASVERRSKTDRYAFLLDKALLICKRRGDSYDLKVSVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRAPAHKECLGRVPPCGRHGQDFSGTVKKDKLHRRAQEKKRNELGLPKMEVFQEYYGIPPPPGAFGTFLRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVRPYVHGPPQDLSMHIWYAGPMERAGAEGILINRSDGTYLVRQRVKDTEEFAISIKYNVEVKHIKIMTSEGLYRITEKKAFRGLQELVEFYQQNSLKDCFKSLDTTLQFPYKEPERRAISKPPAGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYC", "length": 822, "header": "tr|A0A9J7H0F4-1|A0A9J7H0F4_CRIGR Computationally mapped isoform of Proto-oncogene vav isoform X3 OS=Cricetulus griseus OX=10029 GN=Vav1 PE=4 SV=1 CANONICAL=A0A9J7FZX3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZX3/entry#A0A9J7JYR5-1", "sequence": { "sequence": "MELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTDDSAMGDEDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEIYEDLMRSESVSTPHFMKPLQRFLKPQEIETIFVNIEELLSVHTHFLKELKDALAAPGAAMLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKIASVERRSKTDRYAFLLDKALLICKRRGDSYDLKVSVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRAPAHKECLGRVPPCGRHGQDFSGTVKKDKLHRRAQEKKRNELGLPKMEVFQEYYGIPPPPGAFGTFLRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVRPYVHGPPQDLSMHIWYAGPMERAGAEGILINRSDGTYLVRQRVKDTEEFAISIKYNVEVKHIKIMTSEGLYRITEKKAFRGLQELVEFYQQNSLKDCFKSLDTTLQFPYKEPERRAISKPPAGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYC", "length": 813, "header": "tr|A0A9J7JYR5-1|A0A9J7JYR5_CRIGR Computationally mapped isoform of Proto-oncogene vav OS=Cricetulus griseus OX=10029 GN=Vav1 PE=4 SV=1 CANONICAL=A0A9J7FZX3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K649-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZX3/entry#A0A9J7K649-1", "sequence": { "sequence": "MELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTDDSAMGDEDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEIYEDLMRSESVSTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIHQHFMKPLQRFLKPQEIETIFVNIEELLSVHTHFLKELKDALAAPGAAMLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKIASVERRSKTDRYAFLLDKALLICKRRGDSYDLKVSVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRAPAHKECLGRVPPCGRHGQDFSGTVKKDKLHRRAQEKKRNELGLPKMEVFQEYYGIPPPPGAFGTFLRLNPGDIVELTKAEAEHNWWEGPPQDLSMHIWYAGPMERAGAEGILINRSDGTYLVRQRVKDTEEFAISIKYNVEVKHIKIMTSEGLYRITEKKAFRGLQELVEFYQQNSLKDCFKSLDTTLQFPYKEPERRAISKPPAGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYC", "length": 823, "header": "tr|A0A9J7K649-1|A0A9J7K649_CRIGR Computationally mapped isoform of Proto-oncogene vav isoform X2 OS=Cricetulus griseus OX=10029 GN=Vav1 PE=4 SV=1 CANONICAL=A0A9J7FZX3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZX3/entry#A0A9J7K9H6-1", "sequence": { "sequence": "MELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTDDSAMGDEDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEIYEDLMRSESVSTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIHQHFMKPLQRFLKPQEIETIFVNIEELLSVHTHFLKELKDALAAPGAAMLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKIASVERRSKTDRYAFLLDKALLICKRRGDSYDLKVSVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRAPAHKECLGRVPPCGRHGQDFSGTVKKDKLHRRAQEKKRNELGLPKMEVFQEYYGIPPPPGAFGTFLRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVRPYVHGPPQDLSMHIWYNVEVKHIKIMTSEGLYRITEKKAFRGLQELVEFYQQNSLKDCFKSLDTTLQFPYKEPERRAISKPPAGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYC", "length": 806, "header": "tr|A0A9J7K9H6-1|A0A9J7K9H6_CRIGR Computationally mapped isoform of Proto-oncogene vav OS=Cricetulus griseus OX=10029 GN=Vav1 PE=4 SV=1 CANONICAL=A0A9J7FZX3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZX3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZX3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZX3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZX3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765426", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765426", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELWRQCTHWLIQCRVLPPSHRVTWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNRGIMPFPTEEESVGDEDIYSGLSDQIDDTVEEDEDLYDCVENEEAEGDEIYEDLMRSEPVSMPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFLVYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRGDSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPPCGRHGQDFPGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEYC", "length": 845 }, "evidence": [ { "id": "A0A9J7FZX3", "url": "https://omabrowser.org/oma/group/A0A9J7FZX3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P27870-1", "protein_name": "Proto-oncogene vav", "gene_name": "Vav1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELWRQCTHWLIQCRVLPPSHRVTWEGAQVCELAQALRDGVLLCQLLNNLLPQAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNKGIMPFPTEDSALNDEDIYSGLSDQIDDTAEEDEDLYDCVENEEAEGDEIYEDLMRLESVPTPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDMETIFVNIEELFSVHTHFLKELKDALAGPGATTLYQVFIKYKERFLVYGRYCSQVESASKHLDQVATAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQDATEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLANYGRPKIDGELKITSVERRSKTDRYAFLLDKALLICKRRGDSYDLKASVNLHSFQVRDDSSGERDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCYRCRAPAHKECLGRVPPCGRHGQDFAGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGIPPPPGAFGPFLRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVHPYVHGPPQDLSVHLWYAGPMERAGAEGILTNRSDGTYLVRQRVKDTAEFAISIKYNVEVKHIKIMTSEGLYRITEKKAFRGLLELVEFYQQNSLKDCFKSLDTTLQFPYKEPERRAISKPPAGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYC", "length": 845 }, "evidence": [ { "id": "A0A9J7FZX3", "url": "https://omabrowser.org/oma/group/A0A9J7FZX3/", "database": "OMA" } ], "glygen_name": 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pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7JSL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1040, "header": "tr|A0A9J7G1B2-1|A0A9J7G1B2_CRIGR Isoform 1 of Protein phosphatase 1 regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp1r12b PE=4 SV=1 CANONICAL=A0A9J7G1B2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G005-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2/entry#A0A9J7G005-1", "sequence": { "sequence": "MAELEHLGGKRAESARARRAEQLRRWRGSQTEQEPVERQGTGRQLQTRRGSPRVRFEDGAVFLAACSSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRREEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYDLNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEMLQKKQNVLRSEKETRNKLIESDLHSKFQSGLFKNKEKMLYEEENPKSQETEEENKNSSSSSSEEEEGEDEVSESETEKEADKKPEATVNHSNSESKSSIMEQIPAPAQNTFSASSTRRLSSLFNKTEEPKDESPSSWRLGLRKTGSHNMLSEVANSREAFRDRGSSIYRSSSSPRISALLDDKDKERENKNYFSTLAPRRLSSTSDIEEKENRESAVNLVRSGSHSRQLWRDETKGNETPRTIAPSTYVSTYLKRTPYKSQADSTPEKTTDGVSSSSPLCVITNRPAPSTANGVPAATVFSSTGTDSSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAEKTFSRSRAEKQAQEQPGEKLEDPGGLEGSTKKQEPSAAPTKEAGEDQQPWGRSLEEEPIYRRLRCPTQPDKPTTPESPSASRPFLYTSSHLLRTSRASVPDSENSETTINATAAKEMDKNEKEGDNLDDQSSNTLTIRERRRPKDRRRGTGINFWTNDEDEDVSEEVKEKWHERLSRLESGGSNPTSSDSYSDRTSARARREAREARLASLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKMAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 980, "header": "tr|A0A9J7G005-1|A0A9J7G1B2_CRIGR Computationally mapped isoform of Protein phosphatase 1 regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp1r12b PE=4 SV=1 CANONICAL=A0A9J7G1B2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2/entry#A0A9J7G1B2-1", "sequence": { "sequence": "MAELEHLGGKRAESARARRAEQLRRWRGSQTEQEPVERQGTGRQLQTRRGSPRVRFEDGAVFLAACSSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRREEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYDLNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEMLQKKQNVLRSEKETRNKLIESDLHSKFQSGLFKNKEKMLYEEENPKSQETEEENKNSSSSSSEEEEGEDEVSESETEKEADKKPEATVNHSNSESKSSIMEQIPAPAQNTFSASSTRRLSSLFNKTEEPKDESPSSWRLGLRKTGSHNMLSEVANSREAFRDRGSSIYRSSSSPRISALLDDKDKERENKNYFSTLAPRRLSSTSDIEEKENRESAVNLVRSGSHSRQLWRDETKGNETPRTIAPSTYVSTYLKSASFGKSSDPTSPYISANRNSSPATSPITIGSSTSRGSQWQPASCPAPVSTNTAASVQHVRTPYKSQADSTPEKTTDGVSSSSPLCVITNRPAPSTANGVPAATVFSSTGTDSSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAEKTFSRSRAEKQAQEQPGEKLEDPGGLEGSTKKQEPSAAPTKEAGEDQQPWGRSLEEEPIYRRLRCPTQPDKPTTPESPSASRPFLYTSSHLLRTSRASVPDSENSETTINATAAKEMDKNEKEGDNLDDQSSNTLTIRERRRPKDRRRGTGINFWTNDEDEDVSEEVKEKWHERLSRLESGGSNPTSSDSYSDRTSARARREAREARLASLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKMAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 1040, "header": "tr|A0A9J7G1B2-1|A0A9J7G1B2_CRIGR Isoform 1 of Protein phosphatase 1 regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp1r12b PE=4 SV=1 CANONICAL=A0A9J7G1B2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G325-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2/entry#A0A9J7G325-1", "sequence": { "sequence": "MAELEHLGGKRAESARARRAEQLRRWRGSQTEQEPVERQGTGRQLQTRRGSPRVRFEDGAVFLAACSSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRREEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYDLNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEMLQKKQNVLRSEKETRNKLIESDLHSKFQSGLFKNKEKMLYEEENPKSQETEEENKNSSSSSSEEEEGEDEVSESETEKEADKKPEATVNHSNSESKSSIMEQIPAPAQNTFSASSTRRLSSLFNKTEEPKDESPSSWRLGLRKTGSHNMLSEVANSREAFRDRGSSIYRSSSSPRISALLDDKDKERENKNYFSTLAPRRLSSTSDIEEKENRESAVNLVRSGSHSRQLWRDETKGNETPRTIAPSTYVSTYLKRTPYKSQADSTPEKTTDGVSSSSPLCVITNRPAPSTANGVPAATVFSSTGTDSSVEAREKRRSYLTPVRDEEAESLRKARSRQARQTRRSTQGVTLTDLQEAEKTFSRSRAEKQAQEQPGEKLEDPGGLEGSTKKQEPSAAPTKEAGEDQQPWGRSLEEEPIYRRLRCPTQPDKPTTPESPSASRPFLYTSSHLLRTSRASVPDSENSETTINATAAKEMDKNEKEGDNLDDQSSNTLTIRERRRPKDRRRGTGINFWTNDEDEDVSEEVKEKWHERLSRLESGGSNPTSSDSYSDRTSARARREAREARLASLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKMAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKNLHQLKQIQTLKQMNEQLQAENRALTRVVARLSKSIESSDTQDL", "length": 996, "header": "tr|A0A9J7G325-1|A0A9J7G325_CRIGR Computationally mapped isoform of Protein phosphatase 1 regulatory subunit OS=Cricetulus griseus OX=10029 GN=Ppp1r12b PE=4 SV=1 CANONICAL=A0A9J7G1B2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G476-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2/entry#A0A9J7G476-1", "sequence": { "sequence": "MAELEHLGGKRAESARARRAEQLRRWRGSQTEQEPVERQGTGRQLQTRRGSPRVRFEDGAVFLAACSSGDTDEVKKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAEYFISHGASVGIVNSEGEVPSDLAEEPAMKDLLLEQVKKQGVDLEQSRREEEQQMLQDARQWLNSGKIEDVRQARSGATALHVAAAKGYSEVLRLLIQAGYDLNVQDHDGWTPLHAAAHWGVKEACSILAEALCDMDIRNKLGQTPFDVADEGLVEHLEMLQKKQNVLRSEKETRNKLIESDLHSKFQSGLFKNKEKMLYEEENPKSQETEEENKNSSSSSSEEEEGEDEVSESETEKEADKKPEATVNHSNSESKSSIMEQIPAPAQNTFSASSTRRLSSLFNKTEEPKDESPSSWRLGLRKTGSHNMLSEVANSREAFRDRGSSIYRSSSSPRISALLDDKDKERENKNYFSTLAPRRLSSTSDIEEKENRESAVNLVRSGSHSRQLWRDETKGNETPRTIAPSTYVSTYLKRSIKM", "length": 559, "header": "tr|A0A9J7G476-1|A0A9J7G476_CRIGR Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B OS=Cricetulus griseus OX=10029 GN=Ppp1r12b PE=4 SV=1 CANONICAL=A0A9J7G1B2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2/entry#A0A9J7JSL0-1", "sequence": { "sequence": "MSSLYTRSKEFTRNRKSQSDSPPASPSPTAKTLRHERLSRLESGGSNPTSSDSYSDRTSARARREAREARLASLTSRVEEDSNRDYKKLYESALTENQKLKTKLQEAQLELADIKSKLEKMAQQKQEKTSDRSSVLEMEKRERRALERKMSEMEEEMKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 186, "header": "tr|A0A9J7JSL0-1|A0A9J7JSL0_CRIGR Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X4 OS=Cricetulus griseus OX=10029 GN=Ppp1r12b PE=4 SV=1 CANONICAL=A0A9J7G1B2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G005", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G005" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G005", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G005" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753601", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753601", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "enzyme inhibitor activity", "id": "GO:0004857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004857", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2" } ], "pmid": "" }, { "name": "phosphatase regulator activity", "id": "GO:0019208", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019208", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2" } ], "pmid": "" }, { "name": "A band", "id": "GO:0031672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031672", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G1B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B2" }, { "id": "PF15898", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15898" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "cGMP-dependent protein kinase interacting", "eco_id": "ECO_0000259", "start_pos": 939, "end_pos": 1040, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 356, "end_pos": 358 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 574, "end_pos": 576 }, { "start_pos": 827, "end_pos": 829 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G031-1", "uniprot_ac": "A0A9J7G031", "uniprot_id": "A0A9J7G031_CRIGR", "mass": { "chemical_mass": 103373.0, "monoisotopic_mass": 103373.0 }, "refseq": { "ac": "XP_003513583", "name": "CWF19-like protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513583" }, "gene_names": [ { "name": "Cwf19l2", "type": "recommended", "evidence": [ { "id": "A0A9J7G031", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031" } ] }, { "name": "Cwf19l2", "type": "synonym", "evidence": [ { "id": "XP_003513583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513583" } ] } ], "protein_names": [ { "name": "CWF19-like protein 2", "type": "recommended", "evidence": [ { "id": "A0A9J7G031", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031/entry#names_and_taxonomy" } ] }, { "name": "CWF19-like protein 2", "type": "synonym", "evidence": [ { "id": "XP_003513583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513583" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615993.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003513583.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003513583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513583" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G031", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cwf19l2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031", "locus": {} } ], "crossref": [ { "id": "A0A9J7G031", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G031", "database": "AlphaFoldDB", "categories": [] }, { "id": "100761030", "url": "https://www.ncbi.nlm.nih.gov/gene/100761030", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036265", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036265", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761030", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G031", "url": "https://www.orthodb.org/?gene=A0A9J7G031", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12072:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12072:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04676", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04676", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003513583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513583", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G031", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G031-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTATTMAALGGRFESARSIEERKERTRIARAEVLRQAKDNFEKEQRRKELKQLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKVKKEKKKSKKQKYEKQSESTDSSSSSEEWVEAVPFQTLGKEKTWKVKDEKPEEECDRHVMQRDEWMTVDFMSVKTVSSSSIKAEKETLRKTEQEKAQALEQSKLLERELNPYWKDGGTGLPSENCIPAVTKASGVEDGGLSWLRKSYKRMKEQAQKENRNFEDIVAEKYGSMEIFQSKLQEAEKIARKREDCGWERWRKPAYSDRTQCSQASGTSDLVKCKKGSEDKHFATEIANSSSSSDYTFSCPKTGKRSGSLETCRRESTLRQKQESSGNLRPKFLRPSDEDELSFHSKRRNFEPSTFSSTLVAQAPLHFDFRKPTENSEENLTSLSLSGGREGDQKHTDQKPLETWSCSADQHSPGDRREHLQAESLRGDPPRRGQLQDTKSTIAGPEAESTCILSVDEKNKLGAKIIKAEMMGNMELAEQLKAQLKEANRFKETMTQISAKRSGVEHEDEEVILIRTDESGRMWPVNTPRETLDVKAKRRKRQRVATHEDKERIRYFPDDDHLSLNDLVKNEKMGTGIDQNRLFMRMASKFMGKPDGDHYTLDDMFVSKAAEKEHLGEKEESQRRKAIAEHQSLAAQMANCLYCFDSSQFPKHLIVAIGVKVYLCLPNFRSLTEGHCLIVPLQHLQAATMLDEDIWEEIQMFRKSLVKMFEEKGLDCVFLESNMGMKKHYHMVYECIPLPREVGDMAPIYFKKAIMESDEEWSLNKKLIDLSSKDIRKSVPRGLPYFAVDFGLQGGFAHVIEDQHKFPRYFGKEIIGGMLDLEPRLWRKGIRESFEDQRKKALQFAQWWKPFDVTKSKSC", "length": 895, "header": "tr|A0A9J7G031-1|A0A9J7G031_CRIGR Isoform 1 of CWF19-like protein 2 OS=Cricetulus griseus OX=10029 GN=Cwf19l2 PE=3 SV=1 CANONICAL=A0A9J7G031-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G031-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031/entry#A0A9J7G031-1", "sequence": { "sequence": "MTATTMAALGGRFESARSIEERKERTRIARAEVLRQAKDNFEKEQRRKELKQLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKVKKEKKKSKKQKYEKQSESTDSSSSSEEWVEAVPFQTLGKEKTWKVKDEKPEEECDRHVMQRDEWMTVDFMSVKTVSSSSIKAEKETLRKTEQEKAQALEQSKLLERELNPYWKDGGTGLPSENCIPAVTKASGVEDGGLSWLRKSYKRMKEQAQKENRNFEDIVAEKYGSMEIFQSKLQEAEKIARKREDCGWERWRKPAYSDRTQCSQASGTSDLVKCKKGSEDKHFATEIANSSSSSDYTFSCPKTGKRSGSLETCRRESTLRQKQESSGNLRPKFLRPSDEDELSFHSKRRNFEPSTFSSTLVAQAPLHFDFRKPTENSEENLTSLSLSGGREGDQKHTDQKPLETWSCSADQHSPGDRREHLQAESLRGDPPRRGQLQDTKSTIAGPEAESTCILSVDEKNKLGAKIIKAEMMGNMELAEQLKAQLKEANRFKETMTQISAKRSGVEHEDEEVILIRTDESGRMWPVNTPRETLDVKAKRRKRQRVATHEDKERIRYFPDDDHLSLNDLVKNEKMGTGIDQNRLFMRMASKFMGKPDGDHYTLDDMFVSKAAEKEHLGEKEESQRRKAIAEHQSLAAQMANCLYCFDSSQFPKHLIVAIGVKVYLCLPNFRSLTEGHCLIVPLQHLQAATMLDEDIWEEIQMFRKSLVKMFEEKGLDCVFLESNMGMKKHYHMVYECIPLPREVGDMAPIYFKKAIMESDEEWSLNKKLIDLSSKDIRKSVPRGLPYFAVDFGLQGGFAHVIEDQHKFPRYFGKEIIGGMLDLEPRLWRKGIRESFEDQRKKALQFAQWWKPFDVTKSKSC", "length": 895, "header": "tr|A0A9J7G031-1|A0A9J7G031_CRIGR Isoform 1 of CWF19-like protein 2 OS=Cricetulus griseus OX=10029 GN=Cwf19l2 PE=3 SV=1 CANONICAL=A0A9J7G031-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G031", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G031", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761030", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761030", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G031", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "post-mRNA release spliceosomal complex", "id": "GO:0071014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071014", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G031", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G031", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031" }, { "id": "PF04677", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04677" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cwf19-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 665, "end_pos": 787, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G031", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G031" }, { "id": "PF04676", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04676" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cwf19-like protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 796, "end_pos": 890, "start_aa": "Glu", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 324, "end_pos": 326 }, { "start_pos": 415, "end_pos": 417 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G039-1", "uniprot_ac": "A0A9J7G039", "uniprot_id": "A0A9J7G039_CRIGR", "mass": { "chemical_mass": 77803.0, "monoisotopic_mass": 77803.0 }, "refseq": { "ac": "XP_027272576", "name": "zinc finger protein 665 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272576" }, "gene_names": [ { "name": "LOC100759388", "type": "recommended", "evidence": [ { "id": "A0A9J7G039", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ] }, { "name": "LOC100759388", "type": "synonym", "evidence": [ { "id": "XP_027272576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272576" } ] } ], "protein_names": [ { "name": "Zinc finger protein 665 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7G039", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 665 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027272576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272576" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272576" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100759388", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039", "locus": {} } ], "crossref": [ { "id": "A0A9J7G039", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G039", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759388", "url": "https://www.ncbi.nlm.nih.gov/gene/100759388", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759388", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759388", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G039", "url": "https://www.orthodb.org/?gene=A0A9J7G039", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF218", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF218", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G039-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4E6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVSSVNVPQDLLTFGDVAVDFSQEEWECLESASKALYIDVMLENYHNLVFVGKKYLHEEYLPHQKYHMYVKNMKVLDQESKHIVYHPVNIQEKSYENNEMGIKVHKFSHCTPHNTSDLSENSNKYECDNQKDTSIESTNLKNHKCRNTGEETYKYKDYGKWLNLCSSISQRIYPRKELHKNTDYDESFDSKHTLMLKQISGVGKIHQCGKCGKYFRAYSSLSRHQRTHSGEKSYKCKECWMCPLYQVKNHYKTHNGERPYKYSDYENCFIQKDHLSTHPRIQPGEKPFKSSDCEKSFAYVSTLGQLQRIHTEEKPFKSNDCEKSFAYVSTLGQHQIINTGDKPYKCSECEKSFPYISSLRKHKRSHTGEKPYRCSKCEKSFTQGSHLKRHQALHTGENPYKSSDCEKSFPYISSLRKHQQIHTGEKLFKSSDCEKSFSYVSTFGQHQQIHTGEKLFKSNDCEKSIVYVSTLGQLQRIHTGEKLFKSSDCEKSFAYVSTLGQLQRIHTGEKLFKSNDCEKSFAYVSTLGQLQRIHTGEKLFKSNDCEKSFAYVSTLGQHQVINTEDKPYKCSECEKSFPYISSLRKHKRSHTGEKPYRCSKCEKSFTQGSHLRQHQTLHTGEKPYKCNECNKPFTQASHLRRHQIIHTGEKIVSVANVAKYLSSLTSKNT", "length": 670, "header": "tr|A0A9J7G039-1|A0A9J7G039_CRIGR Isoform 1 of Zinc finger protein 665 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100759388 PE=3 SV=1 CANONICAL=A0A9J7G039-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G039-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039/entry#A0A9J7G039-1", "sequence": { "sequence": "MAVSSVNVPQDLLTFGDVAVDFSQEEWECLESASKALYIDVMLENYHNLVFVGKKYLHEEYLPHQKYHMYVKNMKVLDQESKHIVYHPVNIQEKSYENNEMGIKVHKFSHCTPHNTSDLSENSNKYECDNQKDTSIESTNLKNHKCRNTGEETYKYKDYGKWLNLCSSISQRIYPRKELHKNTDYDESFDSKHTLMLKQISGVGKIHQCGKCGKYFRAYSSLSRHQRTHSGEKSYKCKECWMCPLYQVKNHYKTHNGERPYKYSDYENCFIQKDHLSTHPRIQPGEKPFKSSDCEKSFAYVSTLGQLQRIHTEEKPFKSNDCEKSFAYVSTLGQHQIINTGDKPYKCSECEKSFPYISSLRKHKRSHTGEKPYRCSKCEKSFTQGSHLKRHQALHTGENPYKSSDCEKSFPYISSLRKHQQIHTGEKLFKSSDCEKSFSYVSTFGQHQQIHTGEKLFKSNDCEKSIVYVSTLGQLQRIHTGEKLFKSSDCEKSFAYVSTLGQLQRIHTGEKLFKSNDCEKSFAYVSTLGQLQRIHTGEKLFKSNDCEKSFAYVSTLGQHQVINTEDKPYKCSECEKSFPYISSLRKHKRSHTGEKPYRCSKCEKSFTQGSHLRQHQTLHTGEKPYKCNECNKPFTQASHLRRHQIIHTGEKIVSVANVAKYLSSLTSKNT", "length": 670, "header": "tr|A0A9J7G039-1|A0A9J7G039_CRIGR Isoform 1 of Zinc finger protein 665 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100759388 PE=3 SV=1 CANONICAL=A0A9J7G039-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039/entry#A0A9J7G4E6-1", "sequence": { "sequence": "MAVSSVNVPQDLLTFGDVAVDFSQEEWECLESASKALYIDVMLENYHNLVFVEKYHMYVKNMKVLDQESKHIVYHPVNIQEKSYENNEMGIKVHKFSHCTPHNTSDLSENSNKYECDNQKDTSIESTNLKNHKCRNTGEETYKYKDYGKWLNLCSSISQRIYPRKELHKNTDYDESFDSKHTLMLKQISGVGKIHQCGKCGKYFRAYSSLSRHQRTHSGEKSYKCKECWMCPLYQVKNHYKTHNGERPYKYSDYENCFIQKDHLSTHPRIQPGEKPFKSSDCEKSFAYVSTLGQLQRIHTEEKPFKSNDCEKSFAYVSTLGQHQIINTGDKPYKCSECEKSFPYISSLRKHKRSHTGEKPYRCSKCEKSFTQGSHLKRHQALHTGENPYKSSDCEKSFPYISSLRKHQQIHTGEKLFKSSDCEKSFSYVSTFGQHQQIHTGEKLFKSNDCEKSIVYVSTLGQLQRIHTGEKLFKSSDCEKSFAYVSTLGQLQRIHTGEKLFKSNDCEKSFAYVSTLGQLQRIHTGEKLFKSNDCEKSFAYVSTLGQHQVINTEDKPYKCSECEKSFPYISSLRKHKRSHTGEKPYRCSKCEKSFTQGSHLRQHQTLHTGEKPYKCNECNKPFTQASHLRRHQIIHTGEKIVSVANVAKYLSSLTSKNT", "length": 658, "header": "tr|A0A9J7G4E6-1|A0A9J7G4E6_CRIGR Computationally mapped isoform of Zinc finger protein 420 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100759388 PE=3 SV=1 CANONICAL=A0A9J7G039-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759388", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759388", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G039", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G039" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G048-1", "uniprot_ac": "A0A9J7G048", "uniprot_id": "A0A9J7G048_CRIGR", "mass": { "chemical_mass": 16574.0, "monoisotopic_mass": 16574.0 }, "refseq": { "ac": "XP_027272273", "name": "LOW QUALITY PROTEIN: glutaredoxin-related protein 5, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272273" }, "gene_names": [ { "name": "Glrx5", "type": "recommended", "evidence": [ { "id": "A0A9J7G048", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G048" } ] }, { "name": "Glrx5", "type": "synonym", "evidence": [ { "id": "XP_027272273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272273" } ] } ], "protein_names": [ { "name": "Glutaredoxin-related protein 5, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A9J7G048", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G048/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: glutaredoxin-related protein 5, mitochondrial isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027272273", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272273" } ] }, { "name": "Monothiol glutaredoxin-5", "type": "synonym", "evidence": [ { "id": "A0A9J7G048", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G048/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027272273.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272273" } ] }, { "annotation": "Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer. Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion. 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Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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"MEILTSHVQPIFPDQTVVATARALAELLRDAVTYEDVHVNLTHEEWALLDPSQKNLYKDVMLEIYWNLISVGYKWEDHNIEEYCQSSRRHGRYIIFRDTKVASTQEDLYEYKQYDKTFGSASSLKVQQKIHLEVKNYDYNKSIKAFPCHSLDQIHITHSREKAHVYHQCDTAIAHTSYLLIHERTNTGEIPHKCNQCGKAFVLKKNLLRHERIHTGEKPYECNQCGKAFGHKCDLHIHERSHTGEKPYGCNQCGKAFAQKSNLLTHERSHSGEKPYECNHCGKAFGRKCDLHIHEKSHTGEKPYGCNHCGKAFVRKLELQIHERSHTGERPYGCNHCGKTFACKSILHRHERRHSGEKPYGCNQCGKAFAYKNHLQLHERSHTGERPYGCNHCGKTFACKSNLQIHERSHTGEKHYECNQCGKAFAYKSNLQTHERNHTGERPYGCNHCGKTFACKSNLKIHERSHSGEKPYECTQCSKVFAYNSQLHRHEKSHIGEKPYECNHCGKTFACKSNLQIHERSHTGEKPYGYS", "length": 531, "header": "tr|A0A9J7G283-1|A0A9J7G283_CRIGR Isoform 1 of Zinc finger protein OZF isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100766504 PE=3 SV=1 CANONICAL=A0A9J7G283-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G0A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283/entry#A0A9J7G0A9-1", "sequence": { "sequence": "MDAVTYEDVHVNLTHEEWALLDPSQKNLYKDVMLEIYWNLISVGYKWEDHNIEEYCQSSRRHGRYIIFRDTKVASTQEDLYEYKQYDKTFGSASSLKVQQKIHLEVKNYDYNKSIKAFPCHSLDQIHITHSREKAHVYHQCDTAIAHTSYLLIHERTNTGEIPHKCNQCGKAFVLKKNLLRHERIHTGEKPYECNQCGKAFGHKCDLHIHERSHTGEKPYGCNQCGKAFAQKSNLLTHERSHSGEKPYECNHCGKAFGRKCDLHIHEKSHTGEKPYGCNHCGKAFVRKLELQIHERSHTGERPYGCNHCGKTFACKSILHRHERRHSGEKPYGCNQCGKAFAYKNHLQLHERSHTGERPYGCNHCGKTFACKSNLQIHERSHTGEKHYECNQCGKAFAYKSNLQTHERNHTGERPYGCNHCGKTFACKSNLKIHERSHSGEKPYECTQCSKVFAYNSQLHRHEKSHIGEKPYECNHCGKTFACKSNLQIHERSHTGEKPYGYS", "length": 503, "header": "tr|A0A9J7G0A9-1|A0A9J7G283_CRIGR Computationally mapped isoform of Zinc finger protein OZF isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100766504 PE=3 SV=1 CANONICAL=A0A9J7G283-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G283-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283/entry#A0A9J7G283-1", "sequence": { "sequence": "MEILTSHVQPIFPDQTVVATARALAELLRDAVTYEDVHVNLTHEEWALLDPSQKNLYKDVMLEIYWNLISVGYKWEDHNIEEYCQSSRRHGRYIIFRDTKVASTQEDLYEYKQYDKTFGSASSLKVQQKIHLEVKNYDYNKSIKAFPCHSLDQIHITHSREKAHVYHQCDTAIAHTSYLLIHERTNTGEIPHKCNQCGKAFVLKKNLLRHERIHTGEKPYECNQCGKAFGHKCDLHIHERSHTGEKPYGCNQCGKAFAQKSNLLTHERSHSGEKPYECNHCGKAFGRKCDLHIHEKSHTGEKPYGCNHCGKAFVRKLELQIHERSHTGERPYGCNHCGKTFACKSILHRHERRHSGEKPYGCNQCGKAFAYKNHLQLHERSHTGERPYGCNHCGKTFACKSNLQIHERSHTGEKHYECNQCGKAFAYKSNLQTHERNHTGERPYGCNHCGKTFACKSNLKIHERSHSGEKPYECTQCSKVFAYNSQLHRHEKSHIGEKPYECNHCGKTFACKSNLQIHERSHTGEKPYGYS", "length": 531, "header": "tr|A0A9J7G283-1|A0A9J7G283_CRIGR Isoform 1 of Zinc finger protein OZF isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100766504 PE=3 SV=1 CANONICAL=A0A9J7G283-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283/entry#A0A9J7GYK6-1", "sequence": { "sequence": "MEILTSHVQPIFPDQTVVATARALAELLRDAVTYEDVHVNLTHEEWALLDPSQKNLYKDVMLEIYWNLISVGYKWEDHNIEEYCQSSRRHGR", "length": 92, "header": "tr|A0A9J7GYK6-1|A0A9J7GYK6_CRIGR Computationally mapped isoform of Zinc finger protein 431 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100766504 PE=4 SV=1 CANONICAL=A0A9J7G283-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0A9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0A9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0A9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0A9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766504", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766504", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G283", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G283", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G283", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G283", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G283", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G283", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G283", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G283", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 192, "end_pos": 219, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G283", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G283" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 105, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 437, "end_pos": 439 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G0B1-1", "uniprot_ac": "A0A9J7G0B1", "uniprot_id": "A0A9J7G0B1_CRIGR", "mass": { "chemical_mass": 49457.0, "monoisotopic_mass": 49457.0 }, "refseq": { "ac": "XP_003499490", "name": "macrophage receptor MARCO", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499490" }, "gene_names": [ { "name": "Marco", "type": "recommended", "evidence": [ { "id": "A0A9J7G0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0B1" } ] }, { "name": "Marco", "type": "synonym", "evidence": [ { "id": "XP_003499490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499490" } ] } ], "protein_names": [ { "name": "Macrophage receptor MARCO", "type": "synonym", "evidence": [ { "id": "A0A9J7G0B1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0B1/entry#names_and_taxonomy" } ] }, { "name": "macrophage receptor MARCO", "type": "synonym", "evidence": [ { "id": "XP_003499490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499490" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613737.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003499490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499490" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0B1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0B1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Marco", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0B1", "locus": {} } ], "crossref": [ { "id": "A0A9J7G0B1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G0B1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100760468", "url": "https://www.ncbi.nlm.nih.gov/gene/100760468", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760468", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760468", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0B1", "url": "https://www.orthodb.org/?gene=A0A9J7G0B1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003499490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499490", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G0B1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0B1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDKETLKEEAFLGSTEEGADFDQAMFRVMETFEINDPVPKKRNWGSFFMAVMAIHLILLTAGTTLLMLKVVSLQKWILEKCLDNETLAAEDRSFFSLQLASPQTQLVPGKPQLQALQVQLTEVRISQKQLLQQVDNLTRNPEMFRIKGEPGSPGVPGPRGQPGIKGEAGLQGLMGAPGKQGATGAPGPQGEKGSKGDKGLIGPKGEIGTKGDKGDIGLPGSKGDMGMKGVTGVMGPPGAQGDKGNPGKPGLPGLAGSPGVKGDQGQPGVQGVPGTPGAAGPSGAKGEPGHPGPPGPTGPPGISGNPGAAGVKGSKGDTGIQGQKGTKGESGVPGLAGRKGDTGNPGLAGPKGEPGRPGLKGDPGMKGSSGQPGQKGEKGQKGQSFLEVRIVGGTNRGRAEIFYNNVWGTICDDGWDNNDASVFCRMLGYSSGRGFTQGGGSGTIWLDDVNCLGTENSLWSCRKSNWGSHNCNHNEDAGVECR", "length": 483, "header": "tr|A0A9J7G0B1-1|A0A9J7G0B1_CRIGR Isoform 1 of Macrophage receptor MARCO OS=Cricetulus griseus OX=10029 GN=Marco PE=4 SV=1 CANONICAL=A0A9J7G0B1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G0B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0B1/entry#A0A9J7G0B1-1", "sequence": { "sequence": 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Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 235 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614391.1) and transcript sequence (IACG01071528.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007646262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646262" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam20b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5", "locus": {} } ], "crossref": [ { "id": "cd10470", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10470", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772950", "url": "https://www.ncbi.nlm.nih.gov/gene/100772950", "database": "GeneID", "categories": [ "Genome 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12450:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12450:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06702", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06702", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007646262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QED0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QED0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QED0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QED0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0C5-1", "url": 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772950", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772950", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUZ4-1", "protein_name": "FAM20B, glycosaminoglycan xylosylkinase", "gene_name": "Fam20b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLKQRVVVLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLTLEGGQKVVFKPKRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSITLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPIAPVLSDPHLDTVDQRLLNVLATIKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "A0A9J7G0C5", "url": "https://omabrowser.org/oma/group/A0A9J7G0C5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NZJ0-1", "protein_name": "FAM20B, glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMASLRVELDPRLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMSTKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYARDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLGTFMTVGNNTCFYGKCYYCRETEPACADGDIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAIFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPALDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKTAMSHDPISPVLSDPHLDALDQRLLSILATVKQCTDQFGPDVVLVEDRMTLSHL", "length": 409 }, "evidence": [ { "id": "A0A9J7G0C5", "url": "https://omabrowser.org/oma/group/A0A9J7G0C5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S6Y3-1", "protein_name": "FAM20B glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMAGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYNRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDTMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNSLKNGVLKSALKSAMAHDPISPVLSDPHLDALDQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "A0A9J7G0C5", "url": "https://omabrowser.org/oma/group/A0A9J7G0C5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6RNG7-1", "protein_name": "FAM20B glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMAGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAILHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYNRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDTMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNSLKNGVLKSALKSAMAHDPISPVLSDPHLDAVEQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "A0A9J7G0C5", "url": "https://omabrowser.org/oma/group/A0A9J7G0C5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O75063-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "FAM20B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELAPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAVMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDHVVEGEPYAGYDRHNAEVAAFHLDRILGFHRAPLVVGRFVNLRTEIKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDIMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDAVDQRLLSVLATVKQCTDQFGMDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "A0A9J7G0C5", "url": "https://omabrowser.org/oma/group/A0A9J7G0C5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RH51-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "fam20b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLKQRVVVLCAVLFLLGLAKVFLLDGGEGSAASRRDLRAFRKMEASLSLAKGARLTHTLQSPWEVAAQWVGPREVYPDETPELAAVLNALATAHVERADVGYKGTQLKALLVLDGGQKVVFKPKRYVRDYVVEGEPYAGYDRHNAEIAAFHLDRILGFRRAPLVVGRFMNLRTEIKPVATDQLLSTFLMHGNNTCFYGKCYYCRETEPACAEGDVMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCEAVKKMPPYDAGPRLLDVIDTSIFDYLIGNADRHHYESFQDDGGASMLILLDNAKSFGNPSLDERSILAPLYQCCMVRVSTWNRLNLLKGGVLSSAMRQATAHDPAFPVLTGAHLTALDRRLNGVLATVRQCMETQGSENTLIEDRMNLPHP", "length": 409 }, "evidence": [ { "id": "A0A9J7G0C5", "url": "https://omabrowser.org/oma/group/A0A9J7G0C5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VCS3-1", "protein_name": "Glycosaminoglycan xylosylkinase", "gene_name": "Fam20b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLKQRVVLLAILLVIFIFTKVFLIDNLDTSAANREDQRAFHRMMTGLRVELVPKLDHTLQSPWEIAAQWVVPREVYPEETPELGAIMHAMATKKIIKADVGYKGTQLKALLILEGGQKVVFKPKRYSRDYVVEGEPYAGYDRHNAEVAAFHLDRILGFRRAPLVVGRYVNLRTEVKPVATEQLLSTFLTVGNNTCFYGKCYYCRETEPACADGDMMEGSVTLWLPDVWPLQKHRHPWGRTYREGKLARWEYDESYCDAVKKTSPYDSGPRLLDIIDTAVFDYLIGNADRHHYESFQDDEGASMLILLDNAKSFGNPSLDERSILAPLYQCCIIRVSTWNRLNYLKNGVLKSALKSAMAHDPISPVLSDPHLDTVDQRLLNVLATIKQCTDQFGTDTVLVEDRMPLSHL", "length": 409 }, "evidence": [ { "id": "A0A9J7G0C5", "url": "https://omabrowser.org/oma/group/A0A9J7G0C5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q95T10-1", "protein_name": "Glycosaminoglycan xylosylkinase homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNKRSVIIAGIVASLLGLALGANFYFMYYLSAEEGHLASVRALENMIRHKMRHLKPNYLNRNPRFFMFRNKLLKNYKAAPYENASVLWDIANWWPHENEVYPLYDSSMGQLLETLRREPITRVSNLGRGTQLKLLVRLSHQQKVIFKPQWYPREEVIDGMIYSGKDRHTAEVYAFYLGAVLDFRWTPIVVGRVVNLKKEIYAKGDPELQQTINIETDEDGREKYCLFGKCHYCNEEETVCGDERHNIEGVLIYIVPGTLAKRRSPWQRTYKDDKRAPWEDDMTYCKSLKNKMETIRLLDLIDASIFDYLIQNGDRHHYETREERVVLIDNGKAFGNPNKDHLDILAPLYQCCLLRKSTWDRLQVFSGGVLTEIIDRLSKQDALYPLITDKHKKGVERRLLVVYAVVEHCMDIEGDKMFKTL", "length": 421 }, "evidence": [ { "id": "A0A9J7G0C5", "url": "https://omabrowser.org/oma/group/A0A9J7G0C5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5" } ], "pmid": "" }, { "name": "phosphotransferase activity, alcohol group as acceptor", "id": "GO:0016773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016773", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteoglycan biosynthetic process", "id": "GO:0030166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030166", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G0C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5" }, { "id": "PF06702", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06702" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM20 C-terminal", "eco_id": "ECO_0000259", "start_pos": 204, "end_pos": 411, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A8C2QED0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QED0#function" }, { "id": "A0A8C2QED0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QED0" }, { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 142, "amino_acid": "Arg", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 142, "end_pos": 142, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G0C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5#function" }, { "id": "A0A9J7G0C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0C5" }, { "id": "PIRSR624869-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR624869-3" } ], "binding_site_uniprot": 155, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_29035", "ligand": "Mn(2+)", "ligand_label": 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"yes" } }, { "uniprot_canonical_ac": "A0A9J7G0E3-1", "uniprot_ac": "A0A9J7G0E3", "uniprot_id": "A0A9J7G0E3_CRIGR", "mass": { "chemical_mass": 43264.0, "monoisotopic_mass": 43264.0 }, "refseq": { "ac": "XP_027273671", "name": "serpin B7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273671" }, "gene_names": [ { "name": "Serpinb7", "type": "recommended", "evidence": [ { "id": "A0A9J7G0E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0E3" } ] }, { "name": "Serpinb7", "type": "synonym", "evidence": [ { "id": "XP_027273671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273671" } ] } ], "protein_names": [ { "name": "Serpin B7", "type": "recommended", "evidence": [ { "id": "A0A9J7G0E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0E3/entry#names_and_taxonomy" } ] }, { "name": "Megsin", "type": "synonym", "evidence": [ { "id": "A0A9J7G0E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0E3/entry#names_and_taxonomy" } ] }, { "name": "serpin B7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027273671", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273671" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273671" } ] }, { "annotation": "Might function as an inhibitor of Lys-specific proteases. 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This record is derived from a genomic sequence (NW_003613901.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502550" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0J1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100767372", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0J1", "locus": {} } ], "crossref": [ { "id": "A0A9J7G0J1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G0J1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100767372", "url": "https://www.ncbi.nlm.nih.gov/gene/100767372", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767372", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767372", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0J1", "url": "https://www.orthodb.org/?gene=A0A9J7G0J1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502550", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502550", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G0J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0J1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVHLQRMVVQNCSSFLIKRNKQTFSTEPNNPKVRNFFLYNLETKTVGVEPVANCKGVVVVMKCRSCQRKPATLSSIGHLIRKNKYRLDLHMEAIRRSSAILQSQKPVVVKRKHTHPTKSS", "length": 121, "header": "tr|A0A9J7G0J1-1|A0A9J7G0J1_CRIGR Isoform 1 of Large ribosomal subunit protein eL28 OS=Cricetulus griseus OX=10029 GN=LOC100767372 PE=3 SV=1 CANONICAL=A0A9J7G0J1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G0J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0J1/entry#A0A9J7G0J1-1", "sequence": { "sequence": "MSVHLQRMVVQNCSSFLIKRNKQTFSTEPNNPKVRNFFLYNLETKTVGVEPVANCKGVVVVMKCRSCQRKPATLSSIGHLIRKNKYRLDLHMEAIRRSSAILQSQKPVVVKRKHTHPTKSS", "length": 121, "header": "tr|A0A9J7G0J1-1|A0A9J7G0J1_CRIGR Isoform 1 of Large ribosomal subunit protein eL28 OS=Cricetulus griseus OX=10029 GN=LOC100767372 PE=3 SV=1 CANONICAL=A0A9J7G0J1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273281", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273281" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Camsap2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7", "locus": {} } ], "crossref": [ { "id": "100758440", "url": "https://www.ncbi.nlm.nih.gov/gene/100758440", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" 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"categories": [ "Protein Classification" ] }, { "id": "IPR058042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758440", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758440", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0L7", "url": "https://www.orthodb.org/?gene=A0A9J7G0L7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21595", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21595", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21595:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21595:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08683", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08683", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11971", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11971", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17095", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17095", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273281", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273281", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G0L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G195", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G195", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G195-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G195-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGDAADPREMRRTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFGTENVPEELQEPFYTDQYDQEHIKPPVVNLLLSAELYCRAGSLILKSDAAKPLLGHDAVIQALAQKGLYVTDQEKLVTERDLHKKPIQMSAHLAMIDTLMMAYTVEMVSIEKVIACAQQYSAFFQATDLPYDIEDAVMYWINKVNEHLKDIMEQEQKSKEHHTAEAPGGQKARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPAVVRLEDICLKETMSLADSLYNLQLIQEFCQEYLNHCCHFSLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQPRVVRPQGAEPVKDVPSVPVLNAAKRNIMDNSSSSDFTSRYARPQARSSASGGIRRSSSMSYVDGFIGTWPKEKRTSVHGVSFDISFDKEDSAQSSTPNRGIIRSVSNEGLTLNNSRASRHIRKNLSFKPVNGEEDEDEEEEGIEEELHVDPHTDLKSYMPLNTNELNSNESAHYRLPNGALQNRVLLDEFGNQIETPSIEEALQIIHDTEKTPHTPRPDQIANGFFLHSQDLSILNSNIKLNQSSPDNVTDTKGALSPITDTTEVDTGIHVPSEDIPETMDEDSSLRDYTVSLDSDMDDASKFLQDYDIRASNPREALSPCPSTISTKSQPGSSASSSSGVKMTSFAEQKFRKLNHTDGKSSGSSSQKTTPEGSELNIPHVVSWAQIPEETGIAQGRDTTQLLASEVVQLRMRLEEKRRAIEAQKKKMEAAFTRQRQKMGRTAFLTVVKKKGDGISPLREEAAGAEDEKVYTDRTKEKESQKMDGQRSKSLADIKESMENPQGKWLKSPTTPVDPEKQWNLASPSEENLNEGEILEYTKSIEKLNSSLHFLQQEMQRLSLQQEMLMQMREQQSWVISPPQPSPQKQIRDFKPRQAGLSSAAAPFSSDSPRPTHPSPQSSNRKSASFSVKNQRTPRPNELKITPLNRTLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDDGEPQLKEPKPKEIKKEPSECKGTLEPCDRNPGEKEIKPVESTVSEVLSQPITETVCVTPNEDQLSQPTDPPPKPVFPPSAPKNVNLIEVSLSDLKPPEKADVSVENYGGESDKEQCDDDQKVCCGFFFKDDQKAENDMAMKRAALLEKRLRREKETQLRKQQLEAEMEHKKEETRRKTEEERQKKEDERARREFIRQEYMRRKQLKLMEDMDTVIKPRPQVAKQKKPRPKSIHRDHIESPKTPTKGPPVSSLSLASLNTGDNESLHSGKRTPRSESVEGFLSPSRCGSRNGEKDWENASTTSSVASGTEYTGPKLYKEPSAKSNKHIIQNALAHCCLAGKVNEGQKKKILEEMEKSDANNFLILFRDSGCQFRSLYTYCPETEEINKLTGIGPKSITKKMIEGLYKYNSDRKQFSHIPAKTLSASVDAITIHSHLWQTKRPVTPKKLLPTKA", 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"length": 1466, "header": "tr|A0A9J7G0L7-1|A0A9J7G0L7_CRIGR Isoform 1 of Calmodulin-regulated spectrin-associated protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Camsap2 PE=3 SV=1 CANONICAL=A0A9J7G0L7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G195-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7/entry#A0A9J7G195-1", "sequence": { "sequence": "MGDAADPREMRRTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFGTENVPEELQEPFYTDQYDQEHIKPPVVNLLLSAELYCRAGSLILKSDAAKPLLGHDAVIQALAQKGLYVTDQEKLVTERDLHKKPIQMVNEHLKDIMEQEQKSKEHHTAEAPGGQKARYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPAVVRLEDICLKETMSLADSLYNLQLIQEFCQEYLNHCCHFSLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQPRVVRPQGAEPVKDVPSVPVLNAAKRNIMDNSSSSDFTSRYARPQARSSASGGIRRSSSMSYVDGFIGTWPKEKRTSVHGVSFDISFDKEDSAQSSTPNRGIIRSVSNEGLTLNNSRASRHIRKNLSFKPVNGEEDEDEEEEGIEEELHVDPHTDLKSYMPLNTNELNSNESAHYRLPNGALQNRVLLDEFGNQIETPSIEEALQIIHDTEKTPHTPRPDQIANGFFLHSQDLSILNSNIKLNQSSPDNVTDTKGALSPITDTTEVDTGIHVPSEDIPETMDEDSSLRDYTVSLDSDMDDASKFLQDYDIRASNPREALSPCPSTISTKSQPGSSASSSSGVKMTSFAEQKFRKLNHTDGKSSGSSSQKTTPEGSELNIPHVVSWAQIPEETGIAQGRDTTQLLASEVVQLRMRLEEKRRAIEAQKKKMEAAFTRQRQKMGRTAFLTVVKKKGDGISPLREEAAGAEDEKVYTDRTKEKESQKMDGQRSKSLADIKESMENPQGKWLKSPTTPVDPEKQWNLASPSEENLNEGEILEYTKSIEKLNSSLHFLQQEMQRLSLQQEMLMQMREQQSWVISPPQPSPQKQIRDFKPRQAGLSSAAAPFSSDSPRPTHPSPQSSNRKSASFSVKNQRTPRPNELKITPLNRTLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDDGEPQLKEPKPKEIKKEPSECKGTLEPCDRNPGEKEIKPVESTVSEVLSQPITETVCVTPNEDQLSQPTDPPPKPVFPPSAPKNVNLIEVSLSDLKPPEKADVSVENYGGESDKEQCDDDQKVCCGFFFKDDQKAENDMAMKRAALLEKRLRREKETQLRKQQLEAEMEHKKEETRRKTEEERQKKEDERARREFIRQEYMRRKQLKLMEDMDTVIKPRPQVAKQKKPRPKSIHRDHIESPKTPTKGPPVSSLSLASLNTGDNESLHSGKRTPRSESVEGFLSPSRCGSRNGEKDWENASTTSSVASGTEYTGPKLYKEPSAKSNKHIIQNALAHCCLAGKVNEGQKKKILEEMEKSDANNFLILFRDSGCQFRSLYTYCPETEEINKLTGIGPKSITKKMIEGLYKYNSDRKQFSHIPAKTLSASVDAITIHSHLWQTKRPVTPKKLLPTKA", "length": 1412, "header": "tr|A0A9J7G195-1|A0A9J7G195_CRIGR Computationally mapped isoform of Calmodulin-regulated spectrin-associated protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Camsap2 PE=3 SV=1 CANONICAL=A0A9J7G0L7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758440", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758440", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7" } ], "pmid": "" }, { "name": "spectrin binding", "id": "GO:0030507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030507", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7" } ], "pmid": "" }, { "name": "microtubule minus-end binding", "id": "GO:0051011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051011", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "neuron projection development", "id": "GO:0031175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031175", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7" } ], "pmid": "" }, { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0L7" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": 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In addition, participates in the glucocorticoid metabolism by catalyzing the NADPH-dependent cortisol/corticosterone into 20beta-dihydrocortisol (20b-DHF) or 20beta-corticosterone (20b-DHB), which are weak agonists of NR3C1 and NR3C2 in adipose tissue.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0M3#function" }, { "database": "UniProtKB", "id": "ARBA00046189", "url": "https://www.uniprot.org/uniprotkb/ARBA00046189#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0M3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100752270", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0M3", "locus": {} } ], "crossref": [ { "id": "A0A9J7G0M3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G0M3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05324", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05324", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752270", "url": "https://www.ncbi.nlm.nih.gov/gene/100752270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752270", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752270", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0M3", "url": "https://www.orthodb.org/?gene=A0A9J7G0M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43963", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43963", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43963:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43963:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271431", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19257", "url": "https://www.rhea-db.org/rhea/19257", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSRRVALVTGANKDIGFAITRELCRKFSGDVVLTARDEDRGKEAVQQLQEEGLSPRFHQLDIDDLQSIRALRDFLLQEYGGLDVLINNAYIAFKNADPTPFHIQAEVTMKTNFFGTQDVCTELLPLIKPQGRVVNISSMVSLRALENCSPELQQKFRSDTITEEELAELMNKFVEATKRGMHEMEGWPNSAYAVSKIGVTVLSRIHARELSQQRRDDKILLNACCPGWVRTDLTGPKAPKSLEEGAETPVYLALLPPDAEGPHGQFVQQKKVEEW", "length": 277, "header": "tr|A0A9J7G0M3-1|A0A9J7G0M3_CRIGR Isoform 1 of Carbonyl reductase (NADPH) OS=Cricetulus griseus OX=10029 GN=LOC100752270 PE=3 SV=1 CANONICAL=A0A9J7G0M3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G0M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0M3/entry#A0A9J7G0M3-1", "sequence": { "sequence": "MSSSRRVALVTGANKDIGFAITRELCRKFSGDVVLTARDEDRGKEAVQQLQEEGLSPRFHQLDIDDLQSIRALRDFLLQEYGGLDVLINNAYIAFKNADPTPFHIQAEVTMKTNFFGTQDVCTELLPLIKPQGRVVNISSMVSLRALENCSPELQQKFRSDTITEEELAELMNKFVEATKRGMHEMEGWPNSAYAVSKIGVTVLSRIHARELSQQRRDDKILLNACCPGWVRTDLTGPKAPKSLEEGAETPVYLALLPPDAEGPHGQFVQQKKVEEW", "length": 277, "header": "tr|A0A9J7G0M3-1|A0A9J7G0M3_CRIGR Isoform 1 of Carbonyl reductase (NADPH) OS=Cricetulus griseus OX=10029 GN=LOC100752270 PE=3 SV=1 CANONICAL=A0A9J7G0M3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027271445.1. 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"id": "IPR035965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753141", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753141", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0M4", "url": "https://www.orthodb.org/?gene=A0A9J7G0M4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23043", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23043", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23043:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23043:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G0M4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0M4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], 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"phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0M4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0M4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753141", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753141", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "tube development", "id": "GO:0035295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035295", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0M4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0M4" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": 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"https://www.ncbi.nlm.nih.gov/protein/XP_007645707" }, "gene_names": [ { "name": "LOC100769498", "type": "recommended", "evidence": [ { "id": "A0A9J7G0N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8" } ] }, { "name": "LOC100769498", "type": "synonym", "evidence": [ { "id": "XP_007645707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645707" } ] } ], "protein_names": [ { "name": "Zinc finger protein 791", "type": "synonym", "evidence": [ { "id": "A0A9J7G0N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 791", "type": "synonym", "evidence": [ { "id": "XP_007645707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645707" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614316.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645707" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100769498", "url": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13913", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13913", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G0N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHKMEPVTFEDVAVNFTSGEWALLDSSQKKLYRDVMKETFLNLMSIEKGLEQNIEEHYKDFCRNLRTQLVEKDGGYEYNSQCDDNLQTISKNMVNEDMPPAIGNESKLHVRNIIDHSSSLVYLRNQTRGKPSQCKEASRHQKHWKNVSHSESLQVHETFPREKSYKNQQCREGSRSLSSNQPHKRTQCGDKLNGKIFNRHTYSSKDDGIHTEVKSFVHNHNEEAFNDSSDLIIPEKSHIGEKKYICKQCGKTFKYASCFEKHKITHTGEKPYACKHCGKTFTSSSWCNTHERGHNGEKPYMCKHCGKTFRSSSYCNIHERIHTGEKPYACKHCGKTFAILRSRNSHEKNHTGEKMHACKCCGKNFNSPTSCSIHERIHTGEKPYTCKHCGKTFASLTGCITHERNHTGEKPYTCKHCGKAFNNSSYRNVHERIHTGEKPYACKHCGKTFVILGSLITHERSHTGEKPFTCQHCGKSFSQASYRNIHERIHTGEQPYECKYCGKTFAISSSRNTHEKIHTGEKPYTCKHCGKAFISSIWCNAHERSHTGEKPYACKHCGKMFAILSSRNTHEKLHTGEKPYTCKHCGKAFTSSGYRNKHERGHTGEKP", "length": 607, "header": "tr|A0A9J7G0N8-1|A0A9J7G0N8_CRIGR Isoform 1 of Zinc finger protein 791 OS=Cricetulus griseus OX=10029 GN=LOC100769498 PE=3 SV=1 CANONICAL=A0A9J7G0N8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G0N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8/entry#A0A9J7G0N8-1", "sequence": { "sequence": "MHKMEPVTFEDVAVNFTSGEWALLDSSQKKLYRDVMKETFLNLMSIEKGLEQNIEEHYKDFCRNLRTQLVEKDGGYEYNSQCDDNLQTISKNMVNEDMPPAIGNESKLHVRNIIDHSSSLVYLRNQTRGKPSQCKEASRHQKHWKNVSHSESLQVHETFPREKSYKNQQCREGSRSLSSNQPHKRTQCGDKLNGKIFNRHTYSSKDDGIHTEVKSFVHNHNEEAFNDSSDLIIPEKSHIGEKKYICKQCGKTFKYASCFEKHKITHTGEKPYACKHCGKTFTSSSWCNTHERGHNGEKPYMCKHCGKTFRSSSYCNIHERIHTGEKPYACKHCGKTFAILRSRNSHEKNHTGEKMHACKCCGKNFNSPTSCSIHERIHTGEKPYTCKHCGKTFASLTGCITHERNHTGEKPYTCKHCGKAFNNSSYRNVHERIHTGEKPYACKHCGKTFVILGSLITHERSHTGEKPFTCQHCGKSFSQASYRNIHERIHTGEQPYECKYCGKTFAISSSRNTHEKIHTGEKPYTCKHCGKAFISSIWCNAHERSHTGEKPYACKHCGKMFAILSSRNTHEKLHTGEKPYTCKHCGKAFTSSGYRNKHERGHTGEKP", "length": 607, "header": "tr|A0A9J7G0N8-1|A0A9J7G0N8_CRIGR Isoform 1 of Zinc finger protein 791 OS=Cricetulus griseus OX=10029 GN=LOC100769498 PE=3 SV=1 CANONICAL=A0A9J7G0N8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769498", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769498", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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}, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 244, "end_pos": 271, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G0N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N8" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 88, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G0P4-1", "uniprot_ac": "A0A9J7G0P4", "uniprot_id": "A0A9J7G0P4_CRIGR", "mass": { "chemical_mass": 129650.0, "monoisotopic_mass": 129650.0 }, "refseq": { "ac": "XP_027273145", "name": "uncharacterized protein KIAA1614 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273145" }, "gene_names": [ { "name": "Kiaa1614", "type": "recommended", "evidence": [ { "id": "A0A9J7G0P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0P4" } ] }, { "name": "Kiaa1614", "type": "synonym", "evidence": [ { "id": "XP_027273145", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273145" } ] } ], "protein_names": [ { "name": "Uncharacterized protein KIAA1614 homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7G0P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0P4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA1614 homolog", "type": "synonym", "evidence": [ { "id": "XP_027273145", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273145" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273145", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273145" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0P4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kiaa1614", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0P4", "locus": {} } ], "crossref": [ { "id": "A0A9J7G0P4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G0P4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100754212", "url": "https://www.ncbi.nlm.nih.gov/gene/100754212", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR14102", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14102", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14102:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14102:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15737", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15737", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273145", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273145", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G0P4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0P4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"monoisotopic_mass": 33188.0 }, "refseq": { "ac": "XP_027269855", "name": "LOW QUALITY PROTEIN: protein phosphatase PTC7 homolog isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269855" }, "gene_names": [ { "name": "Pptc7", "type": "recommended", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] }, { "name": "Pptc7", "type": "synonym", "evidence": [ { "id": "XP_027269855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269855" } ] } ], "protein_names": [ { "name": "Protein phosphatase", "type": "recommended", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.16", "type": "synonym", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: protein phosphatase PTC7 homolog isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027269855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269855" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027269855.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269855" } ] }, { "annotation": "Protein phosphatase that plays an essential role in mitochondrial metabolism and biogenesis. Positively regulates biosynthesis of the ubiquinone, coenzyme Q. Dephosphorylates the ubiquinone biosynthesis protein COQ7 which is likely to lead to its activation. Serves as a crucial sensor for mitophagy, though the underlying mechanism remains ambiguous. May dephosphorylate BNIP3 and NIX and thereby directly regulates mitophagy receptor function and stability. Alternatively, promotes SCF-FBXL4-dependent ubiquitination and degradation of BNIP3 and NIX independently of its catalytic activity to restrain mitophagy.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7#function" }, { "database": "UniProtKB", "id": "ARBA00055082", "url": "https://www.uniprot.org/uniprotkb/ARBA00055082#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pptc7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7", "locus": {} } ], "crossref": [ { "id": "A0A9J7G0U7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G0U7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100750650", "url": "https://www.ncbi.nlm.nih.gov/gene/100750650", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750650", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750650", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0U7", "url": "https://www.orthodb.org/?gene=A0A9J7G0U7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12320", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12320", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12320:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12320:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07228", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07228", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269855", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGRWRGGGSGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVILSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 307, "header": "tr|A0A9J7G0U7-1|A0A9J7G0U7_CRIGR Isoform 1 of Protein phosphatase OS=Cricetulus griseus OX=10029 GN=Pptc7 PE=3 SV=1 CANONICAL=A0A9J7G0U7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G0U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7/entry#A0A9J7G0U7-1", "sequence": { "sequence": "MFSVLSYGRLVARAVLGGLSQTDPRAGRWRGGGSGDYGLVTAGCGFGKDFRKGLLKKGACYGDDACFVARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYCELLQNKVPLLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGVILSDSPDAADSTSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNSNYESIQRTARSIAEQAHELAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD", "length": 307, "header": "tr|A0A9J7G0U7-1|A0A9J7G0U7_CRIGR Isoform 1 of Protein phosphatase OS=Cricetulus griseus OX=10029 GN=Pptc7 PE=3 SV=1 CANONICAL=A0A9J7G0U7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750650", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750650", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "G3I434-1", "G3H622-1", "G3HKY7-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HVT3-1", "A0A061HX98-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A8C2QCP2-1", "A0A8C2LTP5-1", "A0A8C2N2E5-1", "A0A8C2QBZ1-1", "A0A3L7HBF4-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JYW1-1", "A0A3L7I513-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H622-1", "G3HKY7-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "A0A8C2MF90-1", "A0A9J7GX39-1", "G3I434-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HX98-1", "A0A3L7HEJ5-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A8C2ME51-1", "A0A8C2MTQ0-1", "A0A3L7IJ01-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A9J7F6Q7-1", "A0A8C2N2E5-1", "A0A8C2LTP5-1", "A0A8C2QBZ1-1", "A0A8C2QCP2-1", "A0A3L7HBF4-1", "A0A3L7HC66-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JXQ8-1", "A0A9J7JYW1-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HVT3", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + H2O = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] } ] }, { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061I6V7", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] } ] }, { "uniprot_ac": "A0A3L7HBF4", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] } ] }, { "uniprot_ac": "A0A3L7HC66", "gene_name": "Ppp6c", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7HEM4", "gene_name": "Ctdspl2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] } ] }, { "uniprot_ac": "A0A3L7HX32", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] } ] }, { "uniprot_ac": "A0A3L7I513", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] } ] }, { "uniprot_ac": "A0A3L7IJ01", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] } ] }, { "uniprot_ac": "A0A8C2LGL9", 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"3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] } ] }, { "uniprot_ac": "A0A8C2LTP5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYQ8", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] } ] }, { "uniprot_ac": "A0A8C2M5N0", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] } ] }, { "uniprot_ac": "A0A8C2MA30", "gene_name": "Phlpp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] } ] }, { "uniprot_ac": "A0A8C2ME51", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] } ] }, { "uniprot_ac": "A0A8C2MF90", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] } ] }, { "uniprot_ac": "A0A8C2MTQ0", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] } ] }, { "uniprot_ac": "A0A8C2MW37", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2QBZ1", "gene_name": "Ctdspl", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QBZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QBZ1" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": 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"A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F130", "gene_name": "LOC100769947", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F130" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F130", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F130" } ] } ] }, { "uniprot_ac": "A0A9J7F6Q7", "gene_name": "LOC103164195", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] } ] }, { "uniprot_ac": "A0A9J7F890", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FXD0", "gene_name": "Ppm1f", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FXD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXD0" } ] } ] }, { "uniprot_ac": "A0A9J7G0U7", "gene_name": "Pptc7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G0U7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U7" } ] } ] }, { "uniprot_ac": "A0A9J7G1B8", "gene_name": "Phlpp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] } ] }, { "uniprot_ac": "A0A9J7G243", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] } ] }, { "uniprot_ac": "A0A9J7G7W0", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.27", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W0" } ] } ] }, { "uniprot_ac": "A0A9J7GBP5", "gene_name": "Rpap2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] } ] }, { "uniprot_ac": "A0A9J7GD33", "gene_name": "Ublcp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GEM4", "gene_name": "Ppm1e", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEM4" } ] } ] }, { "uniprot_ac": "A0A9J7GJY7", "gene_name": "Ppef1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJY7" } ] } ] }, { "uniprot_ac": "A0A9J7GK96", "gene_name": "Ppm1n", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK96" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK96" } ] } ] }, { "uniprot_ac": "A0A9J7GX39", "gene_name": "Ssh3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GX39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX39" } ] } ] }, { "uniprot_ac": "A0A9J7H9S5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7H9S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9S5" } ] } ] }, { "uniprot_ac": "A0A9J7HCJ8", "gene_name": "Ppp3cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7HCJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HCJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JBH1", "gene_name": "Cdc14a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JBH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH1" } ] } ] }, { "uniprot_ac": "A0A9J7JFN8", "gene_name": "Epm2a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JFN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFN8" } ] } ] }, { "uniprot_ac": "A0A9J7JXQ8", "gene_name": "Ppp2ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ8" } ] } ] }, { "uniprot_ac": "A0A9J7JYW1", "gene_name": "Ctdnep1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7JYW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW1" } ] } ] }, { "uniprot_ac": "A0A9J7K1J8", "gene_name": "LOC100761879", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1J8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7K1J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1J8" } ] } ] }, { "uniprot_ac": "A0A9J7K5S1", "gene_name": "Ilkap", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7K5S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S1" } ] } ] }, { "uniprot_ac": "G3GRD1", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] } ] }, { "uniprot_ac": "G3GV48", "gene_name": "Ppm1b", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GV48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GV48" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": 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"Protein Classification" ] }, { "id": "A0A8C2MM91", "url": "https://www.orthodb.org/?gene=A0A8C2MM91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G0Y2", "url": "https://www.orthodb.org/?gene=A0A9J7G0Y2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G2V4", "url": "https://www.orthodb.org/?gene=A0A9J7G2V4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H1S2", "url": "https://www.orthodb.org/?gene=A0A9J7H1S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10631", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10631", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10631:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10631:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016830340", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830340", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "43140", "url": "https://www.rhea-db.org/rhea/43140", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "83895", "url": "https://www.rhea-db.org/rhea/83895", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MM91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MM91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5A6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1S2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENMAEEELPPQEEEEAQVRVPTPAPDSAPVPAPAADSALDSAPTPDSAPAPALAPAPAPALSPSLASVPEEAESNFFSERHISIQRRLADLEKLALVTEGDDDDGPASSLNSENLGTEKSHTCPLCPKEKFRACSSQKLRRHLQNLHWKISVEFEGYRMCICHLACRPVKPTIVGEQISSKLGAHYHCIICSATITRRTDMLGHVKRHVNKGETKSRYIAASTAKSSNEILKEADTDIQVGPNYSIPQKTDSYFNPKMKLNRQIIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEEDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLLESLHHGLDDVQPLIKTLIFESECTPQSQCSVHAPSNLNKQEENGVFIKTTDDTTVDIYSAQGKRKSSEMIINTAKKQKTDASAVHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLKYSTPTYTGGQSEGPMQSVSEDTVADRVEMSVADKAEASGCRRW", "length": 734, "header": "tr|A0A9J7G2V4-1|A0A9J7G2V4_CRIGR Isoform 1 of tRNA (guanine(27)-N(2))-dimethyltransferase OS=Cricetulus griseus OX=10029 GN=Trmt1l PE=3 SV=1 CANONICAL=A0A9J7G2V4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MM91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4/entry#A0A8C2MM91-1", "sequence": { "sequence": "MENMAEEELPPQEEEEAQVRVPTPAPDSAPVPAPAADSALDSAPTPDSAPAPALAPAPAPALSPSLASVPEEAESKRHISIQRRLADLEKLALVTEGDDDDGPASSLNSENLGTEKSHTCPLCPKEKFRACSSQKLRRHLQNLHWKISVEFEGYRMCICHLACRPVKPTIVGEQISSKLGAHYHCIICSATITRRTDMLGHVKRHVNKGETKSRYIAASTAKSSNEILKEADTDIQVGPNYSIPQKTDSYFNPKMKLNRQIIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEEDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLLESLHHGLDDVQPLIKTLIFESECTPQSQCSVHAPSNLNKQEENGVFIKTTDDTTVDIYSAQGKRKSSEMIINTAKKQKTDASAVHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLKYSTPTYTGGQSEGPMQSVSEDTVADRVEMSVADKAEASGCRRW", "length": 730, "header": "tr|A0A8C2MM91-1|A0A8C2MM91_CRIGR Computationally mapped isoform of tRNA (guanine(27)-N(2))-dimethyltransferase OS=Cricetulus griseus OX=10029 GN=Trmt1l PE=3 SV=1 CANONICAL=A0A9J7G2V4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G0Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4/entry#A0A9J7G0Y2-1", "sequence": { "sequence": "MENMAEEELPPQEEEEAQVRVPTPAPDSAPVPAPAADSALDSAPTPDSAPAPALAPAPAPALSPSLASVPEEAESNFFSERHISIQRRLADLEKLALVTEGDDDDGPASSLNSENLGTEKSHTCPLCPKEKFRACSSQKLRRHLQNLHWKISVEFEGYRMCICHLACRPVKPTIVGEQISSKLGAHYHCIICSATITRRTDMLGHVKRHVNKGETKSRYIAASTAKSSNEILKEADTDIQVGPNYSIPQKTDSYFNPKMKLNRQIIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEEDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLLESLHHGLDDVQPLIKTLIFESECTPQSQCSVHAPSNLNKQGKRKSSEMIINTAKKQKTDASAVHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLKYSTPTYTGGQSEGPMQSVSEDTVADRVEMSVADKAEASGCRRW", "length": 713, "header": "tr|A0A9J7G0Y2-1|A0A9J7G2V4_CRIGR Computationally mapped isoform of tRNA (guanine(27)-N(2))-dimethyltransferase OS=Cricetulus griseus OX=10029 GN=Trmt1l PE=3 SV=1 CANONICAL=A0A9J7G2V4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4/entry#A0A9J7G2V4-1", "sequence": { "sequence": "MENMAEEELPPQEEEEAQVRVPTPAPDSAPVPAPAADSALDSAPTPDSAPAPALAPAPAPALSPSLASVPEEAESNFFSERHISIQRRLADLEKLALVTEGDDDDGPASSLNSENLGTEKSHTCPLCPKEKFRACSSQKLRRHLQNLHWKISVEFEGYRMCICHLACRPVKPTIVGEQISSKLGAHYHCIICSATITRRTDMLGHVKRHVNKGETKSRYIAASTAKSSNEILKEADTDIQVGPNYSIPQKTDSYFNPKMKLNRQIIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEEDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLLESLHHGLDDVQPLIKTLIFESECTPQSQCSVHAPSNLNKQEENGVFIKTTDDTTVDIYSAQGKRKSSEMIINTAKKQKTDASAVHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLKYSTPTYTGGQSEGPMQSVSEDTVADRVEMSVADKAEASGCRRW", "length": 734, "header": "tr|A0A9J7G2V4-1|A0A9J7G2V4_CRIGR Isoform 1 of tRNA (guanine(27)-N(2))-dimethyltransferase OS=Cricetulus griseus OX=10029 GN=Trmt1l PE=3 SV=1 CANONICAL=A0A9J7G2V4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G5A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4/entry#A0A9J7G5A6-1", "sequence": { "sequence": "MENMAEEELPPQEEEEAQVRVPTPAPDSAPVPAPAADSALDSAPTPDSAPAPALAPAPAPALSPSLASVPEEAESKRHISIQRRLADLEKLALVTEGDDDDGPASSLNSENLGTEKSHTCPLCPKEKFRACSSQKLRRHLQNLHWKISVEFEGYRMCICHLACRPVKPTIVGEQISSKLGAHYHCIICSATITRRTDMLGHVKRHVNKGETKSRYIAASTAKSSNEILKEADTDIQVGPNYSIPQKTDSYFNPKMKLNRQIIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEEDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLLESLHHGLDDVQPLIKTLIFESECTPQSQCSVHAPSNLNKQGKRKSSEMIINTAKKQKTDASAVHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLKYSTPTYTGGQSEGPMQSVSEDTVADRVEMSVADKAEASGCRRW", "length": 709, "header": "tr|A0A9J7G5A6-1|A0A9J7G5A6_CRIGR Computationally mapped isoform of tRNA (guanine(27)-N(2))-dimethyltransferase OS=Cricetulus griseus OX=10029 GN=Trmt1l PE=3 SV=1 CANONICAL=A0A9J7G2V4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4/entry#A0A9J7H1S2-1", "sequence": { "sequence": "MCICHLACRPVKPTIVGEQISSKLGAHYHCIICSATITRRTDMLGHVKRHVNKGETKSRYIAASTAKSSNEILKEADTDIQVGPNYSIPQKTDSYFNPKMKLNRQIIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEEDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLLESLHHGLDDVQPLIKTLIFESECTPQSQCSVHAPSNLNKQEENGVFIKTTDDTTVDIYSAQGKRKSSEMIINTAKKQKTDASAVHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLKYSTPTYTGGQSEGPMQSVSEDTVADRVEMSVADKAEASGCRRW", "length": 575, "header": "tr|A0A9J7H1S2-1|A0A9J7H1S2_CRIGR Computationally mapped isoform of tRNA (guanine(26)-N(2))-dimethyltransferase OS=Cricetulus griseus OX=10029 GN=Trmt1l PE=3 SV=1 CANONICAL=A0A9J7G2V4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 45, "start_aa": "Thr", "end_pos": 45, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr45", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 474, "start_aa": "Thr", "end_pos": 474, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr474", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0Y2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0Y2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752418", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752418", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2RSY6-1", "protein_name": "tRNA (guanine(27)-N(2))-dimethyltransferase", "gene_name": "Trmt1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENMAEEELLPQEKEEAQVRVPTPAPDSAPVPAPAADTALDSAPTPDSDPAPALAPAPAPALSPSLASVPEEAESKRHISIQRRLADLEKLAFGTEGDVDSASSLNSDNPGTENSQTCPLCPKEKFRAYSSHKLRRHLQNLHWKISVEFEGYRMCICHLACRPVKPTIVGEQISSKLGAHYHCIICSATITRRTDMLGHVKRHVNKGETKSRYIAASTAKSSNEILKETDTDIQVFPNYSIPQKTDSYFNPKMKLNRQIIFCTLAALAKERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEDDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLFESIHHGLDDIQPLIKTLIFESECTPQSQCSTHAPSNTNKQEENGVFVKTTDDTTIDIYSAQGKRKSNEMAINLAKKQKTDASTAHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLKYSTPTYTGAQSEGQMPPAAEDTVTDRVEMSVSDKAEASGCRRW", "length": 728 }, "evidence": [ { "id": "A0A9J7G2V4", "url": "https://omabrowser.org/oma/group/A0A9J7G2V4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5D7S3-1", "protein_name": "tRNA (guanine(27)-N(2))-dimethyltransferase", "gene_name": "TRMT1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MENMAEEELLPQEKVEVVQVPVPTPTPDSARVPAPAPDSAPVSASTPAPASAPTPASAPVPAPALAQASALSPSLASAPDEAESKRHISIQRQLADLEKLAFVTEGDCDSANSLNSDNLDAGNKQACPLCPKEKFRACNSHKLHRHLQNLHWKVSVEFEGYRMCICHLPCRPVKPNIIGEQISSKMGAHYHCIICSATITRRTDMLGHVRRHVNKGETKSRYIAASAAKPPKEILKEADTDVQVCPNYTVPQKTDSYFNPKMKLNRQLIFCTLAALAKERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQENCHLNKLKVVVDSKEKEEREDILEEGEENLGNIKVTKMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNIRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLSESLHHGLDDIQTLIKTLIFESECTPQFSVHAPSNLNKPEECGVFIKTTDDTTTDSHSAQGKRKSNETTANLVKRQKTDVNTEHPPFYYNIHRHSIKGMNMPKLKKFLCYLSQAGFRVSRTHFDPMGVRTDAPLMQFKSILLKYSTPTYTGGQSEGHVQPASEDTVADRVEMSVNDKAEAGGCRRW", "length": 737 }, "evidence": [ { "id": "A0A9J7G2V4", "url": "https://omabrowser.org/oma/group/A0A9J7G2V4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q496Z9-1", "protein_name": "tRNA (guanine(27)-N(2))-dimethyltransferase", "gene_name": "Trmt1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MENMAEEELLPQEKEEAQVRVPTPDSAPVPAPAADTALDSAPTPDSAPAPALAPAPAPALSPSLASVPEEAESKRHISIQRRLADLEKLAFGTEGDVDSASSLNSDNLENIQTCPLCPKEKFRAYSSHKLRRHLQNLHWKISVEFEGSRMCICHLACRPVKPTIVGEQISSKLGAHYHCIICSATITRRTDMLGHVKRHVNKGETKSRYISASTAKSSNEVLKETDTDIQVFPNYSIPQKTDSYFNPKMKLNRQIIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDGLEDCSTAGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGVEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYKQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLFESIHHGLDDIQPLIKTLIFESECTPQSQCSVHAPSNTNKQEENGVFVKTTDDTTIDIYSAQGKRKSNEMAINVAKKQKTDASTAHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDASLTQFKSILLKYSTPTYTGGQSEGQVPAPEDTVTDPVELSVNDKAEVSGCRRW", "length": 723 }, "evidence": [ { "id": "A0A9J7G2V4", "url": "https://omabrowser.org/oma/group/A0A9J7G2V4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z2T5-1", "protein_name": "tRNA (guanine(27)-N(2))-dimethyltransferase", "gene_name": "TRMT1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENMAEEELLPLEKEEVEVAQVQVPTPARDSAGVPAPAPDSALDSAPTPASAPAPAPALAQAPALSPSLASAPEEAKSKRHISIQRQLADLENLAFVTDGNFDSASSLNSDNLDAGNRQACPLCPKEKFRACNSHKLRRHLQNLHWKVSVEFEGYRMCICHLPCRPVKPNIIGEQITSKMGAHYHCIICSATITRRTDMLGHVRRHMNKGETKSSYIAASTAKPPKEILKEADTDVQVCPNYSIPQKTDSYFNPKMKLNRQLIFCTLAALAEERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQENCHLNKLKVVVDSKEKEKSDDILEEGEKNLGNIKVTKMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNIRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLFESLHHGLDDIQTLIKTLIFESECTPQSQFSIHASSNVNKQEENGVFIKTTDDTTTDNYIAQGKRKSNEMITNLGKKQKTDVSTEHPPFYYNIHRHSIKGMNMPKLKKFLCYLSQAGFRVSRTHFDPMGVRTDAPLMQFKSILLKYSTPTYTGGQSESHVQSASEDTVTERVEMSVNDKAEASGCRRW", "length": 733 }, "evidence": [ { "id": "A0A9J7G2V4", "url": "https://omabrowser.org/oma/group/A0A9J7G2V4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "tRNA (guanine) methyltransferase activity", "id": "GO:0016423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016423", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4" } ], "pmid": "" }, { "name": "tRNA (guanine(26)-N2)-dimethyltransferase activity", "id": "GO:0160104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160104", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4" } ], "pmid": "" }, { "name": "tRNA (guanine(27)-N2)-dimethyltransferase activity", "id": "GO:0160248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0160248", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA N2-guanine methylation", "id": "GO:0002940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002940", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273415", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273415" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G106", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G106" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppp1r15b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G106", "locus": {} } ], "crossref": [ { "id": "A0A9J7G106", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G106", "database": "AlphaFoldDB", "categories": [] }, { "id": "100766520", "url": "https://www.ncbi.nlm.nih.gov/gene/100766520", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019512", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019512", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766520", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766520", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G106", "url": "https://www.orthodb.org/?gene=A0A9J7G106", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16489:SF11", "url": 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"MELGTQGPRMRPAPRRGSWFRLPVLRRWHAGSSEFSTLSSRGNSGDSVLPEPRTRYWAKWLSQLFALLPNLLQKLFIWSHLFGGMIPTRWLDFVANHSALRALRGRQESATPTVQKSLSSLQLDSSEDLGVSPFDWLEEDLQWQYSSSDLELKLKAQESALNSTAHTFVLEQGLWGMELLPSGLQTGLVSHRELGSSPAGPLDTQSVGSFKVVSYLLNHSCLDCLPQLELRCQNSVGAGQLVDFRTLPPENCCRFEGGCHPQPLRAEISATAWQRCPPLSTEGLPEIHHLRMKRLEFLQANKGQELPTPEQDNGYHSLEEEHSLLQRMDSQHCSDKPAQTVFPPGASPEPTEKKTDLLVQEVSQSLQENSPIFGLPVEKEFEEDHTSVVNCSAVEDDLPVSARPVCSNKLIDYILGGATSDMETSSDSEIEESEDWDEEAEDDGFDSDGSLSESEEEEDSEGLHLWNSFYSVDPYNPQNFTATIQTAATVVPGGPCDSGRPLSANSDVGSSSQAGLLPETPWHSSGEEEDWESSADEAENLRLWNSFCNSEDPYNLLNFKAPFQTSGKNWKGCEGSKAPSEAMVAFSGCQKSALLSCKVQMLESQEDCPDYGLGEALSGETCTHNKRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEDAIGYCLTFEHRERMFNRLQEHVSEDTLLLINVKTSEQSAALAHTLSCLRGFS", "length": 722, "header": "tr|A0A9J7G106-1|A0A9J7G106_CRIGR Isoform 1 of Protein phosphatase 1 regulatory subunit 15B isoform X2 OS=Cricetulus griseus OX=10029 GN=Ppp1r15b PE=3 SV=1 CANONICAL=A0A9J7G106-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G106-1", "url": 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CANONICAL=A0A9J7G106-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273696" } ] }, { "annotation": "Catalytic subunit of the THUMPD2-TRM112 methyltransferase complex, that specifically mediates the S-adenosyl-L-methionine-dependent N(2)-methylation of guanosine nucleotides, most probably at position 72 (m2G72), in the U6snRNA of the major spliceosome. This modification in the U6 snRNA affects the constitutive splicing efficiency of introns that have suboptimal splice sites and can impact final mRNA levels.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142#function" }, { "database": "UniProtKB", "id": "ARBA00055679", "url": "https://www.uniprot.org/uniprotkb/ARBA00055679#function" }, { "database": "UniProtKB", "id": "A0A9J7K629", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K629#function" }, { "database": "UniProtKB", "id": "A0A9J7H2S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2S3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Thumpd2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142", "locus": {} } ], "crossref": [ { "id": "A0A9J7G142", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G142", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11715", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11715", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762353", "url": "https://www.ncbi.nlm.nih.gov/gene/100762353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762353", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G142", "url": "https://www.orthodb.org/?gene=A0A9J7G142", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G1P2", "url": "https://www.orthodb.org/?gene=A0A9J7G1P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14911:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14911:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "83423", "url": "https://www.rhea-db.org/rhea/83423", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G142-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1P2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K629", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K629", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K629-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K629-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGAEPGCDPGGGARFFCTAGRGLESFLMREVQARLEATQVEYISGKVFFTTCSDLASMKKLKSAERLFLLIKKQLPITVPSLSKGKILNEMQRLVNDDPGSWLKAISLWKELLECDTKREKVSQRDANPLKRKVGENEIVIAKKLKVEEIQMVEESHREDQRDRLTEYYLEQGNAVTQTEALQEQGPQNDLVKTAGTENLEDLTFRVSCRCSGNIVKAFTAQEVGRVVGIALMRKFGWKANLRNPYLEIFMHLSDAYSVVGIPLFRVPLASRTYIQTAGLRSTIAWAMASIAEIKAGALVLDPMCGLGTILVEAAEEWPDVYYMGADVSDSQLLGACDNLKAAGLADKIDLLQGSVTELPLPSQSVDVIISDIPFGKKFKLGKDIKSILQEMERVLRVDGTMVLLLSEDHRRHLRDCRGSSILLTSQESPPEMKMLLNPDKRTGTSDKVSPSHKASSSQCPRRVLACGSLVPVECFKVSLGKTDAFICKYKKAHASGLSAAGCHEPGAQPEMATLQEFPSPQDSL", "length": 528, "header": "tr|A0A9J7G142-1|A0A9J7G142_CRIGR Isoform 1 of U6 snRNA (guanine-N(2))-methyltransferase THUMPD2 OS=Cricetulus griseus OX=10029 GN=Thumpd2 PE=3 SV=1 CANONICAL=A0A9J7G142-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G142-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142/entry#A0A9J7G142-1", "sequence": { "sequence": "MAAAGAEPGCDPGGGARFFCTAGRGLESFLMREVQARLEATQVEYISGKVFFTTCSDLASMKKLKSAERLFLLIKKQLPITVPSLSKGKILNEMQRLVNDDPGSWLKAISLWKELLECDTKREKVSQRDANPLKRKVGENEIVIAKKLKVEEIQMVEESHREDQRDRLTEYYLEQGNAVTQTEALQEQGPQNDLVKTAGTENLEDLTFRVSCRCSGNIVKAFTAQEVGRVVGIALMRKFGWKANLRNPYLEIFMHLSDAYSVVGIPLFRVPLASRTYIQTAGLRSTIAWAMASIAEIKAGALVLDPMCGLGTILVEAAEEWPDVYYMGADVSDSQLLGACDNLKAAGLADKIDLLQGSVTELPLPSQSVDVIISDIPFGKKFKLGKDIKSILQEMERVLRVDGTMVLLLSEDHRRHLRDCRGSSILLTSQESPPEMKMLLNPDKRTGTSDKVSPSHKASSSQCPRRVLACGSLVPVECFKVSLGKTDAFICKYKKAHASGLSAAGCHEPGAQPEMATLQEFPSPQDSL", "length": 528, "header": "tr|A0A9J7G142-1|A0A9J7G142_CRIGR Isoform 1 of U6 snRNA (guanine-N(2))-methyltransferase THUMPD2 OS=Cricetulus griseus OX=10029 GN=Thumpd2 PE=3 SV=1 CANONICAL=A0A9J7G142-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142/entry#A0A9J7G1P2-1", "sequence": { "sequence": "MAAAGAEPGCDPGGGARFFCTAGRGLESFLMREVQARLEATQVEYISGKVFFTTCSDLASMKKLKSAERLFLLIKKQLPITVPSLSKGKILNEMQRLVNDDPGSWLKAISLWKELLECDTKREKVSQRDANPLKRKVGENEIVIAKKLKVEEIQMVEESHREDQRDRLTEYYLEQGNAVTQTEALQEQGPQNDLVKTAGTENLEDLTFRVSCRCSGNIVKAFTAQEVGRVVGIALMRKFGWKANLRNPYLEIFMHLSDAYSVVGIPLFRVPLASRTYIQTAGLRSTIAWAMASIAEIKAGALVLDPMCGLGTILVEAAEEWPNYHCLHKVWMLLFLTSHLGKSSS", "length": 345, "header": "tr|A0A9J7G1P2-1|A0A9J7G1P2_CRIGR Computationally mapped isoform of THUMP domain-containing protein 2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Thumpd2 PE=3 SV=1 CANONICAL=A0A9J7G142-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142/entry#A0A9J7H2S3-1", "sequence": { "sequence": "MKKLKSAERLFLLIKKQLPITVPSLSKGKILNEMQRLVNDDPGSWLKAISLWKELLECDTKREKVSQRDANPLKRKVGENEIVIAKKLKVEEIQMVEESHREDQRDRLTEYYLEQGNAVTQTEALQEQGPQNDLVKTAGTENLEDLTFRVSCRCSGNIVKAFTAQEVGRVVGIALMRKFGWKANLRNPYLEIFMHLSDAYSVVGIPLFRVPLASRTYIQTAGLRSTIAWAMASIAEIKAGALVLDPMCGLGTILVEAAEEWPDVYYMGADVSDSQLLGACDNLKAAGLADKIDLLQGSVTELPLPSQSVDVIISDIPFGKKFKLGKDIKSILQEMERVLRVDGTMVLLLSEDHRRHLRDCRGSSILLTSQESPPEMKMLLNPDKRTGTSDKVSPSHKASSSQCPRRVLACGSLVPVECFKVSLGKTDAFICKYKKAHASGLSAAGCHEPGAQPEMATLQEFPSPQDSL", "length": 468, "header": "tr|A0A9J7H2S3-1|A0A9J7H2S3_CRIGR Computationally mapped isoform of U6 snRNA (guanine-N(2))-methyltransferase THUMPD2 OS=Cricetulus griseus OX=10029 GN=Thumpd2 PE=3 SV=1 CANONICAL=A0A9J7G142-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K629-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142/entry#A0A9J7K629-1", "sequence": { "sequence": "MGLDLLAKLRITQTVKEVGRVVGIALMRKFGWKANLRNPYLEIFMHLSDAYSVVGIPLFRVPLASRTYIQTAGLRSTIAWAMASIAEIKAGALVLDPMCGLGTILVEAAEEWPDVYYMGADVSDSQLLGACDNLKAAGLADKIDLLQGSVTELPLPSQSVDVIISDIPFGKKFKLGKDIKSILQEMERVLRVDGTMVLLLSEDHRRHLRDCRGSSILLTSQESPPEMKMLLNPDKRTGTSDKVSPSHKASSSQCPRRVLACGSLVPVECFKVSLGKTDAFICKYKKAHASGLSAAGCHEPGAQPEMATLQEFPSPQDSL", "length": 319, "header": "tr|A0A9J7K629-1|A0A9J7K629_CRIGR Computationally mapped isoform of U6 snRNA (guanine-N(2))-methyltransferase THUMPD2 OS=Cricetulus griseus OX=10029 GN=Thumpd2 PE=3 SV=1 CANONICAL=A0A9J7G142-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 81, "start_aa": "Thr", "end_pos": 81, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr81", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762353", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "tRNA (guanine) methyltransferase activity", "id": "GO:0016423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016423", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142" } ], "pmid": "" }, { "name": "snRNA methyltransferase activity", "id": "GO:0106346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106346", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142" } ], "pmid": "" }, { "name": "tRNA methyltransferase complex", "id": "GO:0043527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043527", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G142", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "83423", "name": "", "equation": "guanosine in U6 snRNA + S-adenosyl-L-methionine = N(2)-methylguanosine in U6 snRNA + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "83423", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/83423" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G142" }, { "id": "PS51165", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51165" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "THUMP", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 267, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 81 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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analysis. 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This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152#function" }, { "database": "UniProtKB", "id": "ARBA00057303", "url": "https://www.uniprot.org/uniprotkb/ARBA00057303#function" }, { "database": "UniProtKB", "id": "A0A9J7H0D0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0D0#function" }, { "database": "UniProtKB", "id": "A0A9J7H0T4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0T4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ncf2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152", "locus": {} } ], "crossref": [ { "id": "A0A9J7G152", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G152", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06406", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06406", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12046", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12046", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767090", "url": "https://www.ncbi.nlm.nih.gov/gene/100767090", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767090", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767090", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G152", "url": "https://www.orthodb.org/?gene=A0A9J7G152", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15175", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15175", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15175:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15175:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273174", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G152-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0D0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0D0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0D0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0T4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0T4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLAEAIRLWNEGVLAADNKDWKGALEAFSEVQDPHSRICFNIGCMHTILENMPAAEQAFTKSINRDKHLAVAYFQRGMLYYSMEKYDLAIKDLKEALTQLRGNQLIDYKILGLQFKLFACEVLYNIAFMHAKKEEWKKAEEQLALATNMKSEPRHSKIDKAMESIWKQKLFEPVVIPVGRLFRPNERQVAQLAKKDYLGKATVVASVVHQDNFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETPEELQVMPGNIVFVLKKGSDNWATVMFNGQKGLVPCNYLEPVELRIHPQSQPQEDTSLESDIPPPPSTSAPARSQLSPGHKQKEEPKKVKPSMPMPYMLKVHYKYTVVMETQLGLPYSQLRVMVSKKLGLLPGHTKLSYRPRDSTELLLLSEETMKDAWSQVKNYCLTLWCEHTVGDQGLIDEPKESENFDVNTRTAEPQLKEGSQVTAIFSYEATQPEDLEFVEGDVILVLSHVNEEWLEGECKGKVGIFPKAFVEECATKDLEGTPREV", "length": 526, "header": "tr|A0A9J7G152-1|A0A9J7G152_CRIGR Isoform 1 of Neutrophil cytosol factor 2 OS=Cricetulus griseus OX=10029 GN=Ncf2 PE=3 SV=1 CANONICAL=A0A9J7G152-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G152-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152/entry#A0A9J7G152-1", "sequence": { "sequence": "MSLAEAIRLWNEGVLAADNKDWKGALEAFSEVQDPHSRICFNIGCMHTILENMPAAEQAFTKSINRDKHLAVAYFQRGMLYYSMEKYDLAIKDLKEALTQLRGNQLIDYKILGLQFKLFACEVLYNIAFMHAKKEEWKKAEEQLALATNMKSEPRHSKIDKAMESIWKQKLFEPVVIPVGRLFRPNERQVAQLAKKDYLGKATVVASVVHQDNFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETPEELQVMPGNIVFVLKKGSDNWATVMFNGQKGLVPCNYLEPVELRIHPQSQPQEDTSLESDIPPPPSTSAPARSQLSPGHKQKEEPKKVKPSMPMPYMLKVHYKYTVVMETQLGLPYSQLRVMVSKKLGLLPGHTKLSYRPRDSTELLLLSEETMKDAWSQVKNYCLTLWCEHTVGDQGLIDEPKESENFDVNTRTAEPQLKEGSQVTAIFSYEATQPEDLEFVEGDVILVLSHVNEEWLEGECKGKVGIFPKAFVEECATKDLEGTPREV", "length": 526, "header": "tr|A0A9J7G152-1|A0A9J7G152_CRIGR Isoform 1 of Neutrophil cytosol factor 2 OS=Cricetulus griseus OX=10029 GN=Ncf2 PE=3 SV=1 CANONICAL=A0A9J7G152-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H0D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152/entry#A0A9J7H0D0-1", "sequence": { "sequence": "MSLAEAIRLWNEGVLAADNKDWKGALEAFSEVQDPHSRICFNIGCMHTILENMPAAEQAFTKSINRDKHLAVAYFQRGMLYYSMEKYDLAIKDLKEALTQLRGNQLIDYKILGLQFKLFACEVVASVVHQDNFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETPEELQVMPGNIVFVLKKGSDNWATVMFNGQKGLVPCNYLEPVELRIHPQSQPQEDTSLESDIPPPPSTSAPARSQLSPGHKQKEEPKKVKPSMPMPYMLKVHYKYTVVMETQLGLPYSQLRVMVSKKLGLLPGHTKLSYRPRDSTELLLLSEETMKDAWSQVKNYCLTLWCEHTVGDQGLIDEPKESENFDVNTRTAEPQLKEGSQVTAIFSYEATQPEDLEFVEGDVILVLSHVNEEWLEGECKGKVGIFPKAFVEECATKDLEGTPREV", "length": 445, "header": "tr|A0A9J7H0D0-1|A0A9J7H0D0_CRIGR Computationally mapped isoform of Neutrophil cytosol factor 2 OS=Cricetulus griseus OX=10029 GN=Ncf2 PE=3 SV=1 CANONICAL=A0A9J7G152-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H0T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152/entry#A0A9J7H0T4-1", "sequence": { "sequence": "MSLAEAIRLWNEGVLAADNKDWKGALEAFSEVQDPHSRICFNIGCMHTILENMPAAEQAFTKSINRDKHLAVAYFQRGMLYYSMEKYDLAIKDLKEALTQLRGNQLIDYKILGLQFKLFACEKQKLFEPVVIPVGRLFRPNERQVAQLAKKDYLGKATVVASVVHQDNFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETPEELQVMPGNIVFVLKKGSDNWATVMFNGQKGLVPCNYLEPVELRIHPQSQPQEDTSLESDIPPPPSTSAPARSQLSPGHKQKEEPKKVKPSMPMPYMLKVHYKYTVVMETQLGLPYSQLRVMVSKKLGLLPGHTKLSYRPRDSTELLLLSEETMKDAWSQVKNYCLTLWCEHTVGDQGLIDEPKESENFDVNTRTAEPQLKEGSQVTAIFSYEATQPEDLEFVEGDVILVLSHVNEEWLEGECKGKVGIFPKAFVEECATKDLEGTPREV", "length": 481, "header": "tr|A0A9J7H0T4-1|A0A9J7H0T4_CRIGR Computationally mapped isoform of Neutrophil cytosol factor 2 OS=Cricetulus griseus OX=10029 GN=Ncf2 PE=3 SV=1 CANONICAL=A0A9J7G152-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767090", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767090", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "NADPH oxidase complex", "id": "GO:0043020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152" } ], "pmid": "" }, { "name": "respiratory burst", "id": "GO:0045730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152" } ], "pmid": "" }, { "name": "superoxide anion generation", "id": "GO:0042554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042554", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "superoxide-generating NADPH oxidase activator activity", "id": "GO:0016176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016176", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G152", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G152" }, { "id": "PS51745", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51745" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PB1", "eco_id": "ECO_0000259", "start_pos": 351, "end_pos": 429, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G152", "database": "UniProtKB", "url": 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"monoisotopic_mass": 28963.0 }, "refseq": { "ac": "XP_007632654", "name": "troponin I, slow skeletal muscle isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007632654" }, "gene_names": [ { "name": "Tnni1", "type": "recommended", "evidence": [ { "id": "A0A9J7G160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160" } ] }, { "name": "Tnni1", "type": "synonym", "evidence": [ { "id": "XP_007632654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007632654" } ] } ], "protein_names": [ { "name": "Troponin I, slow skeletal muscle isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7G160", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160/entry#names_and_taxonomy" } ] }, { "name": "troponin I, slow skeletal muscle isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007632654", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007632654" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613706.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007632654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007632654" } ] }, { "annotation": "Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G160", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160#function" }, { "database": "UniProtKB", "id": "ARBA00001988", "url": "https://www.uniprot.org/uniprotkb/ARBA00001988#function" }, { "database": "UniProtKB", "id": "A0A9J7JJ58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ58#function" }, { "database": "UniProtKB", "id": "A0A8C2M663", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M663#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G160", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tnni1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160", "locus": {} } ], "crossref": [ { "id": "A0A9J7G160", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G160", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756622", "url": "https://www.ncbi.nlm.nih.gov/gene/100756622", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756622", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756622", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KQDFRAN", "url": "https://omabrowser.org/oma/group/KQDFRAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2M663", "url": "https://www.orthodb.org/?gene=A0A8C2M663", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G160", "url": "https://www.orthodb.org/?gene=A0A9J7G160", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JJ58", "url": "https://www.orthodb.org/?gene=A0A9J7JJ58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13738:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13738:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00992", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00992", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007632654", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007632654", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M663", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M663", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M663-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M663-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G160", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G160-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ58-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVAWGHRSLAPRRPIVLSQTIRVSVINPGPDGHAARTHLAQGCLQHHRAFTQVDLPALHRCCLATTMPEVERKSKITASRKLMLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ", "length": 254, "header": "tr|A0A9J7G160-1|A0A9J7G160_CRIGR Isoform 1 of Troponin I, slow skeletal muscle isoform X1 OS=Cricetulus griseus OX=10029 GN=Tnni1 PE=3 SV=1 CANONICAL=A0A9J7G160-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M663-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160/entry#A0A8C2M663-1", "sequence": { "sequence": "MPEVERKSKITASRKLMLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ", "length": 187, "header": "tr|A0A8C2M663-1|A0A8C2M663_CRIGR Computationally mapped isoform of Troponin I, slow skeletal muscle isoform X3 OS=Cricetulus griseus OX=10029 GN=Tnni1 PE=3 SV=1 CANONICAL=A0A9J7G160-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G160-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160/entry#A0A9J7G160-1", "sequence": { "sequence": "MGVAWGHRSLAPRRPIVLSQTIRVSVINPGPDGHAARTHLAQGCLQHHRAFTQVDLPALHRCCLATTMPEVERKSKITASRKLMLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ", "length": 254, "header": "tr|A0A9J7G160-1|A0A9J7G160_CRIGR Isoform 1 of Troponin I, slow skeletal muscle isoform X1 OS=Cricetulus griseus OX=10029 GN=Tnni1 PE=3 SV=1 CANONICAL=A0A9J7G160-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ58-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160/entry#A0A9J7JJ58-1", "sequence": { "sequence": "MFVGEKCHFDARCCLATTMPEVERKSKITASRKLMLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ", "length": 205, "header": "tr|A0A9J7JJ58-1|A0A9J7JJ58_CRIGR Computationally mapped isoform of Troponin I, slow skeletal muscle isoform X2 OS=Cricetulus griseus OX=10029 GN=Tnni1 PE=3 SV=1 CANONICAL=A0A9J7G160-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G160", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G160", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756622", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756622", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P13413-1", "protein_name": "Troponin I, slow skeletal muscle", "gene_name": "Tnni1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVERKSKITASRKLMLKSLMLAKAKECWEQEHEEREAEKVRYLSERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTLQ", "length": 187 }, "evidence": [ { "id": "A0A9J7G160", "url": "https://omabrowser.org/oma/group/A0A9J7G160/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P19237-1", "protein_name": "Troponin I, slow skeletal muscle", "gene_name": "TNNI1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ", "length": 187 }, "evidence": [ { "id": "A0A9J7G160", "url": "https://omabrowser.org/oma/group/A0A9J7G160/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WUZ5-1", "protein_name": "Troponin I, slow skeletal muscle", "gene_name": "Tnni1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPEVERKSKITASRKLMLKSLMLAKAKECWEQEHEEREAEKVRYLSERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ", "length": 187 }, "evidence": [ { "id": "A0A9J7G160", "url": "https://omabrowser.org/oma/group/A0A9J7G160/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G160", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160" } ], "pmid": "" }, { "name": "cardiac muscle contraction", "id": "GO:0060048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060048", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G160", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G160", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "troponin complex", "id": "GO:0005861", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005861", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G160", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G160" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], 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Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273329" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G168", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100762307", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168", "locus": {} } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762307", "url": "https://www.ncbi.nlm.nih.gov/gene/100762307", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762307", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762307", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G168", "url": "https://www.orthodb.org/?gene=A0A9J7G168", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18861", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18861", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273329", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G168", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G168-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPLILFAALLWLQGLLAEEDPCPSLEESPDKEGGGPPLSVNVSSQGKPSSLFLSWVSAEPYGLDYALSLRSLNPLGSPEGQPLQAHTNESSFEFHGLVPGSHYQLELTVLRPCWQNVTVTLTAQTAPSEVRGLQLHSSGSPASLEASWSEAPGNQDSYQLLLYHLESQMLACNVSVSPGILSYNFGNLLPGSQYVLEVITWAGSLQAKTSIHQWTEPVPPDHLILRALDTSSLQAFWNVSEGATSLYLMLTDFPGATNLTAVVKQGVSNHTFLHLSPGTPYKLRLYAVAGPHWVVGPNATEWTYPFHPSDLVLTPLPNELWASWEAGPGARDSYVLKLSGPVENTSTLGPEECNAVFPGPLPLGHYTLRLKVLAGPYDAWIEASTWLAEPAALPRESPGARLWLDGLLEATKQPGRRALLYAADAPGLLGNISVPFGATHVTFCGLVPGAHYRVDIASSVGDITQSITGYTRPLPPQSLEVINRSSPSDLTIRWVPAPGQQEGYKFTWHQDGSQRSPGNLVDLGPDNSSLTLRSLVPGSCYTVSAWAWAGNLSSNLRKIHSCTRPAPPTNLSLGFSTQPATLRASWSHPQGGRDGFQLRLYRLRPLALESEKILSREARNFSWAKLAAGSEFQVQLATLWGSEESSSANATGWTPPLAPTLVNVTSEAPTQLQALWVHAPGGRHSYQVSLYQEGARTATSIMGSKANSTTFSGLTPGTKYKVEVISWAGPLYAAASNVSAWTYPLTPNELLVSMQAGSAVVNLAWPSGPLGQGTCHAQLSDAGHLSWEQPLSPGQDHLILTHLTPGHTILMFVKCQAGPLQASTHPVVLSVEPGPVEDVLCQPGATHLVLNWTMPVGDVDACLVAVEQLVGGGSAHFVFQVNTSEDALLLPNLMPATSYRLSLTVLGRNNLWSRAVTLVCTTSTEVWHPPELAEAPQLELGTGTGVTVTRGMFGKDDGQIQWYGIIVTSNMSLTRPSRESVNYTWYDHYYGGRDSYMAVLFPNPFYPGPWAVPRSWTVPVGTEDCGHTQEICNGHLKPGFQYRFSVAAFSRLSLPETITTFSAFSEPQASVSLVAVPVTVMTGTVAGCIFIVCAVLCLLCWWRLKGPRPEKDGFSHELMPYNLRRTHRPIPIHSFRQSYEAKSAHAHQAFFQEFEELKEVGREQPRLEAEHPDNTSKNRYPHVLPYDHSRVRLSPMAGEPHSDYINANFIPGYSHPQEFIATQGPLKKTVEDFWRLVWEQQVHVIIMLTVGMENGRVLCEHYWPANSTPVTHGHITIHLLAEEPEEEWTRREFQLQHDVQQKQRRVKQLQFTTWPDHSVPEAPSSLLKFVELVREQVQVTQGKGPTLVHCSAGVGRTGTFVALLRLLQQLEEEQMVDVFNTVYMLRLHRPLMIQTPSQYIFLHSCLLNKILEGPSDTSDSGPISVMNFAQACAKRAANANAGFLKEYKLLKQAIKYEAGSLMPPPGYNQNSVVSGDHSQMQFSTVEESPADNVLEAWLFPGGPSGRDHVVLTGLARPKELWELVWEHGAHVLVSLGLPDTKEKPQDFWPMEMQPVVTDMVTVHRVSESNTAGWPCTLFRVIHGETGTERQVQRLQFPCWESGCELPATTLLPFLDAVGQCCSRGKSKKPGTLLSHSSKGTNQLGTFLAMEQLLQQAGTECTVDVFNVALKQSQACGLMTPTLEQYIYLYKCLNSALLDGMH", "length": 1702, "header": "tr|A0A9J7G168-1|A0A9J7G168_CRIGR Isoform 1 of Receptor-type tyrosine-protein phosphatase V OS=Cricetulus griseus OX=10029 GN=LOC100762307 PE=3 SV=1 CANONICAL=A0A9J7G168-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G168-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168/entry#A0A9J7G168-1", "sequence": { "sequence": "MRPLILFAALLWLQGLLAEEDPCPSLEESPDKEGGGPPLSVNVSSQGKPSSLFLSWVSAEPYGLDYALSLRSLNPLGSPEGQPLQAHTNESSFEFHGLVPGSHYQLELTVLRPCWQNVTVTLTAQTAPSEVRGLQLHSSGSPASLEASWSEAPGNQDSYQLLLYHLESQMLACNVSVSPGILSYNFGNLLPGSQYVLEVITWAGSLQAKTSIHQWTEPVPPDHLILRALDTSSLQAFWNVSEGATSLYLMLTDFPGATNLTAVVKQGVSNHTFLHLSPGTPYKLRLYAVAGPHWVVGPNATEWTYPFHPSDLVLTPLPNELWASWEAGPGARDSYVLKLSGPVENTSTLGPEECNAVFPGPLPLGHYTLRLKVLAGPYDAWIEASTWLAEPAALPRESPGARLWLDGLLEATKQPGRRALLYAADAPGLLGNISVPFGATHVTFCGLVPGAHYRVDIASSVGDITQSITGYTRPLPPQSLEVINRSSPSDLTIRWVPAPGQQEGYKFTWHQDGSQRSPGNLVDLGPDNSSLTLRSLVPGSCYTVSAWAWAGNLSSNLRKIHSCTRPAPPTNLSLGFSTQPATLRASWSHPQGGRDGFQLRLYRLRPLALESEKILSREARNFSWAKLAAGSEFQVQLATLWGSEESSSANATGWTPPLAPTLVNVTSEAPTQLQALWVHAPGGRHSYQVSLYQEGARTATSIMGSKANSTTFSGLTPGTKYKVEVISWAGPLYAAASNVSAWTYPLTPNELLVSMQAGSAVVNLAWPSGPLGQGTCHAQLSDAGHLSWEQPLSPGQDHLILTHLTPGHTILMFVKCQAGPLQASTHPVVLSVEPGPVEDVLCQPGATHLVLNWTMPVGDVDACLVAVEQLVGGGSAHFVFQVNTSEDALLLPNLMPATSYRLSLTVLGRNNLWSRAVTLVCTTSTEVWHPPELAEAPQLELGTGTGVTVTRGMFGKDDGQIQWYGIIVTSNMSLTRPSRESVNYTWYDHYYGGRDSYMAVLFPNPFYPGPWAVPRSWTVPVGTEDCGHTQEICNGHLKPGFQYRFSVAAFSRLSLPETITTFSAFSEPQASVSLVAVPVTVMTGTVAGCIFIVCAVLCLLCWWRLKGPRPEKDGFSHELMPYNLRRTHRPIPIHSFRQSYEAKSAHAHQAFFQEFEELKEVGREQPRLEAEHPDNTSKNRYPHVLPYDHSRVRLSPMAGEPHSDYINANFIPGYSHPQEFIATQGPLKKTVEDFWRLVWEQQVHVIIMLTVGMENGRVLCEHYWPANSTPVTHGHITIHLLAEEPEEEWTRREFQLQHDVQQKQRRVKQLQFTTWPDHSVPEAPSSLLKFVELVREQVQVTQGKGPTLVHCSAGVGRTGTFVALLRLLQQLEEEQMVDVFNTVYMLRLHRPLMIQTPSQYIFLHSCLLNKILEGPSDTSDSGPISVMNFAQACAKRAANANAGFLKEYKLLKQAIKYEAGSLMPPPGYNQNSVVSGDHSQMQFSTVEESPADNVLEAWLFPGGPSGRDHVVLTGLARPKELWELVWEHGAHVLVSLGLPDTKEKPQDFWPMEMQPVVTDMVTVHRVSESNTAGWPCTLFRVIHGETGTERQVQRLQFPCWESGCELPATTLLPFLDAVGQCCSRGKSKKPGTLLSHSSKGTNQLGTFLAMEQLLQQAGTECTVDVFNVALKQSQACGLMTPTLEQYIYLYKCLNSALLDGMH", "length": 1702, "header": "tr|A0A9J7G168-1|A0A9J7G168_CRIGR Isoform 1 of Receptor-type tyrosine-protein phosphatase V OS=Cricetulus griseus OX=10029 GN=LOC100762307 PE=3 SV=1 CANONICAL=A0A9J7G168-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 950, "start_aa": "Thr", "end_pos": 950, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr950", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G168", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G168", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762307", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762307", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G168", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G168", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cellular response to hormone stimulus", "id": "GO:0032870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032870", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G168", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G168", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ], "pmid": "" }, { "name": "cellular response to oxygen-containing compound", "id": "GO:1901701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901701", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G168", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G168", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1175, "end_pos": 1177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1267, "end_pos": 1269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 708, "end_pos": 710, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 852, "end_pos": 854, "annotation": "n_glycosylation_sequon" }, { "start_pos": 883, "end_pos": 885, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" }, { "start_pos": 971, "end_pos": 973, "annotation": "n_glycosylation_sequon" }, { "start_pos": 983, "end_pos": 985, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H060-1", "G3H622-1", "G3H9Q0-1", "A0A8C2LH05-1", "G3HKY7-1", "G3GWQ6-1", "G3HBF6-1", "G3GRD1-1", "G3H8H2-1", "A0A9J7FG56-1", "A0A061IAM9-1", "A0A9J7GE78-1", "A0A9J7GZK0-1", "A0A061HX98-1", "A0A061HZS8-1", "A0A3L7HEJ5-1", "A0A8C2LYZ8-1", "A0A9J7JC04-1", "A0A8C2MQ28-1", "A0A3L7I231-1", "A0A9J7EY47-1", "A0A8C2LVB9-1", "A0A8C2MZ43-1", "A0A9J7G003-1", "A0A8C2QC02-1", "A0A9J7JD11-1", "A0A8C2QH88-1", "A0A9J7EXY7-1", "A0A9J7JC62-1", "A0A9J7FEN1-1", "A0A9J7FB56-1", "A0A9J7FEZ5-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FWX7-1", "A0A9J7G1A0-1", "A0A9J7JTT7-1", "A0A9J7G7L1-1", "A0A9J7G7K2-1", "A0A9J7GNR2-1", "A0A9J7JU39-1", "A0A9J7KAX8-1", "A0A9J7GQG9-1", "A0A9J7GX92-1", "A0A9J7F2A0-1", "A0A9J7EZC9-1", "A0A9J7EZL1-1", "A0A9J7FIV0-1", "A0A8C2MFV5-1", "A0A8C2N2E5-1", "A0A8C2N686-1", "A0A8C2QCP2-1", "A0A3L7IA07-1", "A0A9J7FYL8-1", "A0A9J7G168-1", "A0A9J7GBQ5-1", "A0A9J7H7L7-1", "A0A9J7HBK7-1", "A0A9J7GQC8-1", "A0A9J7H152-1", "A0A9J7KDA7-1", "A0A9J7KDM0-1", "A0A9J7J766-1", "A0A9J7FKB3-1", "A0A3L7HAL2-1" ], "evidence": [ { "id": "10684", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10684" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061HZS8", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] } ] }, { "uniprot_ac": "A0A061IAM9", "gene_name": "LOC100766206", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] } ] }, { "uniprot_ac": "A0A3L7HAL2", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7I231", "gene_name": "Ptp4a3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] } ] }, { "uniprot_ac": "A0A3L7IA07", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] } ] }, { "uniprot_ac": "A0A8C2LH05", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYZ8", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] } ] }, { "uniprot_ac": "A0A8C2MFV5", "gene_name": "LOC100758361", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] } ] }, { "uniprot_ac": "A0A8C2MQ28", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] } ] }, { "uniprot_ac": "A0A8C2MZ43", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2N686", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] } ] }, { "uniprot_ac": "A0A8C2QC02", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EXY7", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZC9", "gene_name": "Ptpn18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F2A0", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] } ] }, { "uniprot_ac": "A0A9J7FB56", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] } ] }, { "uniprot_ac": "A0A9J7FEN1", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] } ] }, { "uniprot_ac": "A0A9J7FEZ5", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] } ] }, { "uniprot_ac": "A0A9J7FG56", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] } ] }, { "uniprot_ac": "A0A9J7FIV0", "gene_name": "LOC100763249", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FWX7", "gene_name": "LOC103158664", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] } ] }, { "uniprot_ac": "A0A9J7FYL8", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] } ] }, { "uniprot_ac": "A0A9J7G003", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] } ] }, { "uniprot_ac": "A0A9J7G168", "gene_name": "LOC100762307", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] } ] }, { "uniprot_ac": "A0A9J7G1A0", "gene_name": "Ptpn4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] } ] }, { "uniprot_ac": "A0A9J7G7K2", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] } ] }, { "uniprot_ac": "A0A9J7G7L1", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] } ] }, { "uniprot_ac": "A0A9J7GBQ5", "gene_name": "LOC100764354", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GNR2", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] } ] }, { "uniprot_ac": "A0A9J7GQC8", "gene_name": "LOC100757114", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] } ] }, { "uniprot_ac": "A0A9J7GQG9", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] } ] }, { "uniprot_ac": "A0A9J7GX92", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] } ] }, { "uniprot_ac": "A0A9J7GZK0", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] } ] }, { "uniprot_ac": "A0A9J7H152", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] } ] }, { "uniprot_ac": "A0A9J7H7L7", "gene_name": "Ptprh", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H7L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H7L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ] } ] }, { "uniprot_ac": "A0A9J7HBK7", "gene_name": "Ptpn22", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7HBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7HBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ] } ] }, { "uniprot_ac": "A0A9J7J766", "gene_name": "Ptpn20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] } ] }, { "uniprot_ac": "A0A9J7JC04", "gene_name": "Eya3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] } ] }, { "uniprot_ac": "A0A9J7JC62", "gene_name": "Tns2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] } ] }, { "uniprot_ac": "A0A9J7JD11", "gene_name": "Ptprm", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] } ] }, { "uniprot_ac": "A0A9J7JTT7", "gene_name": "Ptpra", "activity": 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"Protein Classification" ] }, { "id": "IPR036375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051298", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051298", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752278", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752278", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G171", "url": "https://www.orthodb.org/?gene=A0A9J7G171", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22917", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22917", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22917:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22917:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00045", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00045", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01033", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01033", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273209", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G171", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G171-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9T2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9T2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9T2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEWKILPICLSLLLPALLIQQVSSQDLSSCAGRCGEGYSRGATCNCDYNCQHYMECCPDFKRVCTTELSCKGRCFESFARGRECDCDSQCREFGKCCDDYDSFCEEVHNPTSPPPKTAPPPPGASHIIKSTTKRSPKSPKKKTKKVVESEEITEEHSVSENQESSSSSSSSSSTIRKIKSSKNSANRELQKNPKVKDNKKNTPKKEPNPEPRGVDEAGSGLDNGEPKPTPIPASPKTTAAKPASAKPSLAPNSETSKEASSTSNKETTVETKETTATNKQTSASKKEKTTSAKEIRSAENKDVAPTSDVPSPTTSKHSAPTTTKKPVPTTTKEPAPTTTKKPVTTTKEPAPTTPQKPEATTPKQPAPTTPKEPAPTTPKEPEATTPKESAPTTPKEPEATTPKEPAPTTPKEPAAIPPKEPAPTTPKEPEATTPKEPAPTTPKEPAATTPKESAPTTPKEPEATTSKESAPTTPKKPEATTSKESAPTTPKEPEATPPKEPAPTTPKKPEATPKEPAPTTSKEPAATPPKEPVPINPKEPEATPPKEPAPTTPKKPAPTTPKEPGATTPKTLAEETPGFSEVPIPEVLENDPKEAPVPPTKTPKVREPETTTADKEKTTEKDTPQTTTVAPKRTTIIPEETNKSETSATTKVTPTTTLAPKVTAPTEETSNKPEETTPAAEGVDTKTTLKPHKPTKVPKKPASTKKPHKAPKKHTSTKKPPTSTKKPKAPKRRKPKTTPPPLKTSAMPELNNTPLEVMLPTTTSPNQTPNSEIAGVNLDPEDADGGDRGKRLIPMPPVLSPIVISGTDHLARELNHGININPMLSDEMNLCNGKPVDGLTTLHNGTLVAFRGHYFWMLNPFRPPSPPRRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDVQDAGYPKQIVKGFGGLTGKIVAALSVAKYKDRPESVYFFKRGGNIQQYTYKHEPMRKCTGRRPAINYSVYGDTAQVRRRRFERAVGPFQTHTFRIHYSMPMRVAYQDKGFLHNEVKVSTMWRGFPNVVTSAITLPNIRKPDGYDYYAFSKDQYYNIDVPTRTARAVTTRSGQTLSKIWYNCP", "length": 1090, "header": "tr|A0A9J7G171-1|A0A9J7G171_CRIGR Isoform 1 of Proteoglycan 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Prg4 PE=4 SV=1 CANONICAL=A0A9J7G171-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G171-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171/entry#A0A9J7G171-1", "sequence": { "sequence": "MEWKILPICLSLLLPALLIQQVSSQDLSSCAGRCGEGYSRGATCNCDYNCQHYMECCPDFKRVCTTELSCKGRCFESFARGRECDCDSQCREFGKCCDDYDSFCEEVHNPTSPPPKTAPPPPGASHIIKSTTKRSPKSPKKKTKKVVESEEITEEHSVSENQESSSSSSSSSSTIRKIKSSKNSANRELQKNPKVKDNKKNTPKKEPNPEPRGVDEAGSGLDNGEPKPTPIPASPKTTAAKPASAKPSLAPNSETSKEASSTSNKETTVETKETTATNKQTSASKKEKTTSAKEIRSAENKDVAPTSDVPSPTTSKHSAPTTTKKPVPTTTKEPAPTTTKKPVTTTKEPAPTTPQKPEATTPKQPAPTTPKEPAPTTPKEPEATTPKESAPTTPKEPEATTPKEPAPTTPKEPAAIPPKEPAPTTPKEPEATTPKEPAPTTPKEPAATTPKESAPTTPKEPEATTSKESAPTTPKKPEATTSKESAPTTPKEPEATPPKEPAPTTPKKPEATPKEPAPTTSKEPAATPPKEPVPINPKEPEATPPKEPAPTTPKKPAPTTPKEPGATTPKTLAEETPGFSEVPIPEVLENDPKEAPVPPTKTPKVREPETTTADKEKTTEKDTPQTTTVAPKRTTIIPEETNKSETSATTKVTPTTTLAPKVTAPTEETSNKPEETTPAAEGVDTKTTLKPHKPTKVPKKPASTKKPHKAPKKHTSTKKPPTSTKKPKAPKRRKPKTTPPPLKTSAMPELNNTPLEVMLPTTTSPNQTPNSEIAGVNLDPEDADGGDRGKRLIPMPPVLSPIVISGTDHLARELNHGININPMLSDEMNLCNGKPVDGLTTLHNGTLVAFRGHYFWMLNPFRPPSPPRRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDVQDAGYPKQIVKGFGGLTGKIVAALSVAKYKDRPESVYFFKRGGNIQQYTYKHEPMRKCTGRRPAINYSVYGDTAQVRRRRFERAVGPFQTHTFRIHYSMPMRVAYQDKGFLHNEVKVSTMWRGFPNVVTSAITLPNIRKPDGYDYYAFSKDQYYNIDVPTRTARAVTTRSGQTLSKIWYNCP", "length": 1090, "header": "tr|A0A9J7G171-1|A0A9J7G171_CRIGR Isoform 1 of Proteoglycan 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Prg4 PE=4 SV=1 CANONICAL=A0A9J7G171-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171/entry#A0A9J7K9T2-1", "sequence": { "sequence": "MEWKILPICLSLLLPALLIQQVSSQDLSSCAGRCGEGYSRGATCNCDYNCQHYMECCPDFKRVCTTELSCKGRCFESFARGRECDCDSQCREFGKCCDDYDSFCEEVKDNKKNTPKKEPNPEPRGVDEAGSGLDNGTDHLARELNHGININPMLSDEMNLCNGKPVDGLTTLHNGTLVAFRGHYFWMLNPFRPPSPPRRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQYWRFTNDVQDAGYPKQIVKGFGGLTGKIVAALSVAKYKDRPESVYFFKRGGNIQQYTYKHEPMRKCTGRRPAINYSVYGDTAQVRRRRFERAVGPFQTHTFRIHYSMPMRVAYQDKGFLHNEVKVSTMWRGFPNVVTSAITLPNIRKPDGYDYYAFSKDQYYNIDVPTRTARAVTTRSGQTLSKIWYNCP", "length": 420, "header": "tr|A0A9J7K9T2-1|A0A9J7K9T2_CRIGR Computationally mapped isoform of Proteoglycan 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Prg4 PE=4 SV=1 CANONICAL=A0A9J7G171-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 313, "start_aa": "Thr", "end_pos": 313, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr313", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 368, "start_aa": "Thr", "end_pos": 368, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr368", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G171", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G171", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752278", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752278", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "polysaccharide binding", "id": "GO:0030247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030247", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G171", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171" } ], "pmid": "" }, { "name": "scavenger receptor activity", "id": "GO:0005044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005044", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G171", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G171", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G171", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" }, { "start_pos": 751, "end_pos": 753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" }, { "start_pos": 974, "end_pos": 976, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G171", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G171" }, { "id": "PS50958", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50958" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SMB", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 69, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 313, 368 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 642, "end_pos": 644 }, { "start_pos": 751, "end_pos": 753 }, { "start_pos": 766, "end_pos": 768 }, { "start_pos": 844, "end_pos": 846 }, { "start_pos": 974, "end_pos": 976 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G181-1", "uniprot_ac": "A0A9J7G181", "uniprot_id": "A0A9J7G181_CRIGR", "mass": { "chemical_mass": 14762.0, "monoisotopic_mass": 14762.0 }, "refseq": { "ac": "XP_027273347", "name": "guanine nucleotide exchange factor MSS4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273347" }, "gene_names": [ { "name": "Rabif", "type": "recommended", "evidence": [ { "id": "A0A9J7G181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G181" } ] }, { "name": "Rabif", "type": "synonym", "evidence": [ { "id": "XP_027273347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273347" } ] } ], "protein_names": [ { "name": "Guanine nucleotide exchange factor MSS4", "type": "recommended", "evidence": [ { "id": "A0A9J7G181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G181/entry#names_and_taxonomy" } ] }, { "name": "Rab-interacting factor", "type": "synonym", "evidence": [ { "id": "A0A9J7G181", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G181/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide exchange factor MSS4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027273347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273347" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273347" } ] }, { "annotation": "Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1, RAB3A and RAB10, but is less active on these proteins than on the SEC4 protein. Might play a general role in vesicular transport.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G181", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G181#function" }, { "database": "UniProtKB", "id": "ARBA00060031", "url": "https://www.uniprot.org/uniprotkb/ARBA00060031#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G181", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G181" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rabif", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G181", "locus": {} } ], "crossref": [ { "id": "A0A9J7G181", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G181", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00246", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00246", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753301", "url": "https://www.ncbi.nlm.nih.gov/gene/100753301", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753301", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753301", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G181", "url": "https://www.orthodb.org/?gene=A0A9J7G181", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13276", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13276", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13276:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13276:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273347", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G181", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G181", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G181-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G181-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLWRRGAAMEPAELQNQLVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPALADGGNPDGDLLQEHWLVNDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE", "length": 131, "header": "tr|A0A9J7G181-1|A0A9J7G181_CRIGR Isoform 1 of Guanine nucleotide exchange factor MSS4 OS=Cricetulus griseus OX=10029 GN=Rabif PE=4 SV=1 CANONICAL=A0A9J7G181-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G181-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G181/entry#A0A9J7G181-1", "sequence": { "sequence": "MLWRRGAAMEPAELQNQLVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPALADGGNPDGDLLQEHWLVNDMFIFENVGFTKDVGNIKFLVCADCEIGPIGWHCLDDKNSFYVALERVSHE", "length": 131, "header": "tr|A0A9J7G181-1|A0A9J7G181_CRIGR Isoform 1 of Guanine nucleotide exchange factor MSS4 OS=Cricetulus griseus OX=10029 GN=Rabif PE=4 SV=1 CANONICAL=A0A9J7G181-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A9J7G496-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G496-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5G8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5G8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5G8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JT76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JT76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JT76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JT76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADWRIGSGAALHLKRTNRTKTWKVTGKLMKVDEHVIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLVETKEKAKEEKEKLEHKYTMQINELEGQFHQKAKEIGMIQTELKTMKEFQKRKIVVEKELDELKENLRNSEKKHQETLKRLESRFFEEKHRLEQEAEKRIVMLAERAHHEAMMQLSTAGRNVFKENVYLHKALTYHLKEAETRQKTSEKLQESHSCLMHQKETNELLIKEKIMQLTQQKSQIQTLQKKVLSLENALTYMTTEFEAEVFKLQQKAIIENQAGKVEIDKLQYLLEMKDKEMNRVKKLAKNILDQRTEVEQFFLDALNQVKQQILINRKHYKQIAQAAFNLKMSAACAGRTEYPRIRTFDGKEHSTNSVNHDLMEAEKWPSTQKNVDIRDLTWEQKEKVLRLLFAKMNGLAARKYRSSSKPPVPDYISDSGEMKETGGEINLPDQTFITQQAPVSDSNKMMSPSIISNGLQDSDIVRNLLFSQTVHHWYLSLCDILLVHSSLLSKQLLGTDCRNFYNNVHTNKAAYYMYLENLLIPF", "length": 595, "header": "tr|A0A9J7G183-1|A0A9J7G183_CRIGR Isoform 1 of Basal body-orientation factor 1 OS=Cricetulus griseus OX=10029 GN=Bbof1 PE=3 SV=1 CANONICAL=A0A9J7G183-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G183-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G183/entry#A0A9J7G183-1", "sequence": { "sequence": "MADWRIGSGAALHLKRTNRTKTWKVTGKLMKVDEHVIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLVETKEKAKEEKEKLEHKYTMQINELEGQFHQKAKEIGMIQTELKTMKEFQKRKIVVEKELDELKENLRNSEKKHQETLKRLESRFFEEKHRLEQEAEKRIVMLAERAHHEAMMQLSTAGRNVFKENVYLHKALTYHLKEAETRQKTSEKLQESHSCLMHQKETNELLIKEKIMQLTQQKSQIQTLQKKVLSLENALTYMTTEFEAEVFKLQQKAIIENQAGKVEIDKLQYLLEMKDKEMNRVKKLAKNILDQRTEVEQFFLDALNQVKQQILINRKHYKQIAQAAFNLKMSAACAGRTEYPRIRTFDGKEHSTNSVNHDLMEAEKWPSTQKNVDIRDLTWEQKEKVLRLLFAKMNGLAARKYRSSSKPPVPDYISDSGEMKETGGEINLPDQTFITQQAPVSDSNKMMSPSIISNGLQDSDIVRNLLFSQTVHHWYLSLCDILLVHSSLLSKQLLGTDCRNFYNNVHTNKAAYYMYLENLLIPF", "length": 595, "header": "tr|A0A9J7G183-1|A0A9J7G183_CRIGR Isoform 1 of Basal body-orientation factor 1 OS=Cricetulus griseus OX=10029 GN=Bbof1 PE=3 SV=1 CANONICAL=A0A9J7G183-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G271-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G183/entry#A0A9J7G271-1", "sequence": { "sequence": "MAWQIEKLKQQLVETKEKAKEEKEKLEHKYTMQINELEGQFHQKAKEIGMIQTELKTMKEFQKRKIVVEKELDELKENLRNSEKKHQETLKRLESRFFEEKHRLEQEAEKRIVMLAERAHHEAMMQLSTAGRNVFKENVYLHKALTYHLKEAETRQKTSEKLQESHSCLMHQKETNELLIKEKIMQLTQQKSQIQTLQKKVLSLENALTYMTTEFEAEVFKLQQKAIIENQAGKVEIDKLQYLLEMKDKEMNRVKKLAKNILDQRTEVEQFFLDALNQVKQQILINRKHYKQIAQAAFNLKMSAACAGRTEYPRIRTFDGKEHSTNSVNHDLMEAEKWPSTQKNVDIRDLTWEQKEKVLRLLFAKMNGLAARKYRSSSKPPVPDYISDSGEMKETGGEINLPDQTFITQQAPVSDSNKMMSPSIISNGLQDSDIVRNLLFSQTVHHWYLSLCDILLVHSSLLSKQLLGTDCRNFYNNVHTNKAAYYMYLENLLIPF", "length": 496, "header": "tr|A0A9J7G271-1|A0A9J7G271_CRIGR Computationally mapped isoform of Basal body-orientation factor 1 OS=Cricetulus griseus OX=10029 GN=Bbof1 PE=3 SV=1 CANONICAL=A0A9J7G183-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G183/entry#A0A9J7G2C0-1", "sequence": { "sequence": "MADWRIGSGAALHLKRTNRTKTWKVTGKLMKVDEHVIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLVETKEKAKEEKEKLEHKYTMQINELEGQFHQKAKEIGMIQTELKTMKEFQKRKIVVEKELDELKENLRNSEKKHQETLKRLESRFFEEKHRLEQEAEKRIVMLAERAHHEAMMQLSTAGRNVFKENVYLHKALTYHLKEAETRQKTSEKLQESHSCLMHQKETNELLIKEKIMQLTQQKSQIQTLQKKVLSLENALTYMTTEFEAEVFKLQQKAIIENQAGKVEIDKLQYLLEMKDKEMNRVKKLAKNILDQRTEVEQFFLDALNQVKQQILINRKHYKQIAQAAFNLKMSAACAGRTEYPRIRTFDGKEHSTNSVNHDLMEAEKWPSTQKNVDIRDLTWEQKEKVLRLLFAKMNGLAARKYRSSSKPPVPDYISDSGEMKETGCLRNRAEKQMAASPFLM", "length": 512, "header": "tr|A0A9J7G2C0-1|A0A9J7G2C0_CRIGR Computationally mapped isoform of Basal body-orientation factor 1 OS=Cricetulus griseus OX=10029 GN=Bbof1 PE=3 SV=1 CANONICAL=A0A9J7G183-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G474-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G183/entry#A0A9J7G474-1", "sequence": { "sequence": "MKVDEHVIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLVETKEKAKEEKEKLEHKYTMQINELEGQFHQKAKEIGMIQTELKTMKEFQKRKIVVEKELDELKENLRNSEKKHQETLKRLESRFFEEKHRLEQEAEKRIVMLAERAHHEAMMQLSTAGRNVFKENVYLHKALTYHLKEAETRQKTSEKLQESHSCLMHQKETNELLIKEKIMQLTQQKSQIQTLQKKVLSLENALTYMTTEFEAEVFKLQQKAIIENQAGKVEIDKLQYLLEMKDKEMNRVKKLAKNILDQRTEVEQFFLDALNQVKQQILINRKHYKQIAQAAFNLKMSAACAGRTEYPRIRTFDGKEHSTNSVNHDLMEAEKWPSTQKNVDIRDLTWEQKEKVLRLLFAKMNGLAARKYRSSSKPPVPDYISDSGEMKETGGEINLPDQTFITQQAPVSDSNKMMSPSIISNGLQDSDIVRNLLFSQTVHHWYLSLCDILLVHSSLLSKQLLGTDCRNFYNNVHTNKAAYYMYLENLLIPF", "length": 566, "header": "tr|A0A9J7G474-1|A0A9J7G474_CRIGR Computationally mapped isoform of Basal body-orientation factor 1 OS=Cricetulus griseus OX=10029 GN=Bbof1 PE=3 SV=1 CANONICAL=A0A9J7G183-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G496-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G183/entry#A0A9J7G496-1", "sequence": { "sequence": "MADWRIGSGAALHLKRTNRTKTWKVTGKLMKVDEHVIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLVETKEKAKEEKEKLEHKYTMQINELEGQFHQKAKEIGMIQTELKTMKEFQKRKIVVEKELDELKENLRNSEKKHQETLKRLESRFFEEKHRLEQEAEKRIVMLAERAHHEAMMQLSTAGRNVFKENVYLHKALTYHLKEAETRQKTSEKLQESHSCLMHQKETNELLIKEKIMQLTQQKSQIQTLQKKVLSLENALTYMTTEFEAEVFKLQQKAIIENQAGKVEIDKLQYLLEMKDKEMNRVKKLAKNILDQRTEVEQFFLDALNQVKQQILINRKHYKQIAQAAFNLKMSAACAGRTEYPRIRTFDGKEHSTNSVNHDLMEAEKWPSTQKNVDIRDLTWEQKEKVLRLLFAKMNGLAARKYRSSSKPPVPDYISDSGEMKETGGEINLPDQTFITQQAPVSDSNKMMSPSIISNGLQDSDIMPEK", "length": 537, "header": "tr|A0A9J7G496-1|A0A9J7G496_CRIGR Computationally mapped isoform of Basal body-orientation factor 1 OS=Cricetulus griseus OX=10029 GN=Bbof1 PE=3 SV=1 CANONICAL=A0A9J7G183-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G5G8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G183/entry#A0A9J7G5G8-1", "sequence": { "sequence": "MPAKDKRKGKNKGKDKKKLMKVDEHVIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLVETKEKAKEEKEKLEHKYTMQINELEGQFHQKAKEIGMIQTELKTMKEFQKRKIVVEKELDELKENLRNSEKKHQETLKRLESRFFEEKHRLEQEAEKRIVMLAERAHHEAMMQLSTAGRNVFKENVYLHKALTYHLKEAETRQKTSEKLQESHSCLMHQKETNELLIKEKIMQLTQQKSQIQTLQKKVLSLENALTYMTTEFEAEVFKLQQKAIIENQAGKVEIDKLQYLLEMKDKEMNRVKKLAKNILDQRTEVEQFFLDALNQVKQQILINRKHYKQIAQAAFNLKMSAACAGRTEYPRIRTFDGKEHSTNSVNHDLMEAEKWPSTQKNVDIRDLTWEQKEKVLRLLFAKMNGLAARKYRSSSKPPVPDYISDSGEMKETGGEINLPDQTFITQQAPVSDSNKMMSPSIISNGLQDSDIVRNLLFSQTVHHWYLSLCDILLVHSSLLSKQLLGTDCRNFYNNVHTNKAAYYMYLENLLIPF", "length": 585, "header": "tr|A0A9J7G5G8-1|A0A9J7G5G8_CRIGR Computationally mapped isoform of Basal body-orientation factor 1 OS=Cricetulus griseus OX=10029 GN=Bbof1 PE=3 SV=1 CANONICAL=A0A9J7G183-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JT76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G183/entry#A0A9J7JT76-1", "sequence": { "sequence": "MADWRIGSGAALHLKRTNRTKTWKVTGKLMKVDEHVIERAKANASLWEARLEVTELSRIEYRDTSRRLAKNNEDLKKQQYKLEKDTMSVLSYLKKQDQEKDNMIEKLKQQLVETKEKAKEEKEKLEHKYTMQINELEGQFHQKAKEIGMIQTELKTMKEFQKRKIVVEKELDEHRLEQEAEKRIVMLAERAHHEAMMQLSTAGRNVFKENVYLHKALTYHLKEAETRQKTSEKLQESHSCLMHQKETNELLIKEKIMQLTQQKSQIQTLQKKVLSLENALTYMTTEFEAEVFKLQQKAIIENQAGKVEIDKLQYLLEMKDKEMNRVKKLAKNILDQRTEVEQFFLDALNQVKQQILINRKHYKQIAQAAFNLKMSAACAGRTEYPRIRTFDGKEHSTNSVNHDLMEAEKWPSTQKNVDIRDLTWEQKEKVLRLLFAKMNGLAARKYRSSSKPPVPDYISDSGEMKETGGEINLPDQTFITQQAPVSDSNKMMSPSIISNGLQDSDIVRNLLFSQTVHHWYLSLCDILLVHSSLLSKQLLGTDCRNFYNNVHTNKAAYYMYLENLLIPF", "length": 568, "header": "tr|A0A9J7JT76-1|A0A9J7JT76_CRIGR Computationally mapped isoform of Basal body-orientation factor 1 OS=Cricetulus griseus OX=10029 GN=Bbof1 PE=3 SV=1 CANONICAL=A0A9J7G183-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G183", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G183" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G183", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G183" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754703", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754703", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G183", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G183" }, { "id": "PF14988", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14988" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4515", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 278, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G191-1", "uniprot_ac": "A0A9J7G191", "uniprot_id": "A0A9J7G191_CRIGR", "mass": { "chemical_mass": 43118.0, "monoisotopic_mass": 43118.0 }, "refseq": { "ac": "XP_027273374", "name": "prolargin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273374" }, "gene_names": [ { "name": "Prelp", "type": "recommended", "evidence": [ { "id": "A0A9J7G191", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191" } ] }, { "name": "Prelp", "type": "synonym", "evidence": [ { "id": "XP_027273374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273374" } ] } ], "protein_names": [ { "name": "Prolargin", "type": "synonym", "evidence": [ { "id": "A0A9J7G191", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191/entry#names_and_taxonomy" } ] }, { "name": "prolargin", "type": "synonym", "evidence": [ { "id": "XP_027273374", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273374" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273374" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G191", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prelp", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191", "locus": {} } ], "crossref": [ { "id": "A0A9J7G191", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G191", "database": "AlphaFoldDB", "categories": [] }, { "id": "100765642", "url": "https://www.ncbi.nlm.nih.gov/gene/100765642", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765642", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765642", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G191", "url": "https://www.orthodb.org/?gene=A0A9J7G191", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273374", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273374", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G191", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G191-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRASFFWTLPLLLTLASVAQGQPRPKPGIRRKPKPRPTPSFPQPHEPAEPTDLPPPLPPGPPSVFPDCPRECYCPADFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPLESFKNATGLRWINLDNNRIRKVDQRVLEKLPSLAFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKADTFQGLKSLMQLNLAHNILRKMPPKVPPAIHQLYLDSNKIETIPNGYFKGFPNLAFIRMNYNKLSDRGLPKNSFNISNLLVLHLSHNKISNVPAISNKLEHLYLNNNSIEKINGTQICPNNLVAFHDFSSDLENVPHLRYLRLDGNFLKPPIPLDLMMCFRLLQSVII", "length": 377, "header": "tr|A0A9J7G191-1|A0A9J7G191_CRIGR Isoform 1 of Prolargin OS=Cricetulus griseus OX=10029 GN=Prelp PE=3 SV=1 CANONICAL=A0A9J7G191-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G191-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191/entry#A0A9J7G191-1", "sequence": { "sequence": "MRASFFWTLPLLLTLASVAQGQPRPKPGIRRKPKPRPTPSFPQPHEPAEPTDLPPPLPPGPPSVFPDCPRECYCPADFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPLESFKNATGLRWINLDNNRIRKVDQRVLEKLPSLAFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKADTFQGLKSLMQLNLAHNILRKMPPKVPPAIHQLYLDSNKIETIPNGYFKGFPNLAFIRMNYNKLSDRGLPKNSFNISNLLVLHLSHNKISNVPAISNKLEHLYLNNNSIEKINGTQICPNNLVAFHDFSSDLENVPHLRYLRLDGNFLKPPIPLDLMMCFRLLQSVII", "length": 377, "header": "tr|A0A9J7G191-1|A0A9J7G191_CRIGR Isoform 1 of Prolargin OS=Cricetulus griseus OX=10029 GN=Prelp PE=3 SV=1 CANONICAL=A0A9J7G191-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 38, "start_aa": "Thr", "end_pos": 38, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr38", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G191", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G191", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765642", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765642", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "heparin binding", "id": "GO:0008201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008201", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G191", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G191", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G191", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G191" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": 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"synonym", "evidence": [ { "id": "A0A9J7G1B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein GLI2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027273616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273616" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273616" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gli2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0", "locus": {} } ], "crossref": [ { "id": "100757572", "url": "https://www.ncbi.nlm.nih.gov/gene/100757572", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] 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"length": 1547, "header": "tr|A0A9J7G1B0-1|A0A9J7G1B0_CRIGR Isoform 1 of Zinc finger protein GLI2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Gli2 PE=3 SV=1 CANONICAL=A0A9J7G1B0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0/entry#A0A9J7G1K6-1", "sequence": { "sequence": "MRHQEGRYHYDPHSVHSVHGPPTLSGSPVISDISLIRLSPHPAGPGESPFSAHHPYMNPHMEHYLRSVHSSPTLSMISAARGLSPADVAHEHLKERGLFGLAAPGTNPSDYYHQMTLMASHPAPYGDLLMQSGGAAGAPHLHDYLNPADASRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLTQQPMALTSISTMPTQLSSNSSNCLNDANQNKQSSESAVSSTVNPITIHKRSKVKTEAEGLRSASPLGLTQEQLADLKEDLDRDDCKQEAEVVIYETNCHWADCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRAPLLKENGDNEASAEPGGQGSEDSVEASSTSHTVEDCLHIKAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALEDTSPGADTSALAAPATGGLQLRKHMTTMHRFEQLKREKLKSLKDSCSWAGPAPHTRNTKLPPLPANGSVLESFNGTGGGGPAGLLPNQRLPELTEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGGPGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERVSLRTRLALLDAPERALPGACPHPLGPRRGSDGPAYSHGHGHGYVGAAPAFPHEGPGSSMRRASDPVRRPDPLILPRVQRFHSTHNMNPGSLPPCTDRRGPHLQSHPSVDSSLTRNTYSPRPPSISENVMMEAIAAGVDGTGLESDLGLVEDELVLPDDVVQYIKAHTSGALDDSTRQGYPTESTGFPENSKLPSPGLQGHRRLAAADSNMSPSAPGLGGCQLSYSPSSNLNKSNMPVQWNEVSSGTMDALPSQVKPPPFPHSNLAVVQQKPAFGQYSGYSPQALQASSGGLDSTQPHLQLRGAPAAPRGSYTQQPRQPATGGQCLSVTAAMSPQASYSQAHPQLSPNIVSGPLNQFSPSCSNMAAKPSHLGLPPQMEVVPNATMMSGHQRELGVANSSLPGVSQPHAVLSYPQQEGYQQGSSLLSSHQPSFMESQQGTGFGLMQPRPPLEPNTASRHRRVHAGQQQLYARTASQAMVTSANQETAEAMPKGTAGTMVSLAPQPSQDTGRSQDQNTLYYYGQIHMYEQNGDCPAMQPQPPQPQACSDNIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPTLLHNLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEENKFLNMMT", "length": 1483, "header": "tr|A0A9J7G1K6-1|A0A9J7G1K6_CRIGR Computationally mapped isoform of Zinc finger protein GLI2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Gli2 PE=3 SV=1 CANONICAL=A0A9J7G1B0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0/entry#A0A9J7H1F5-1", "sequence": { "sequence": "MNPHMEHYLRSVHSSPTLSMISAARGLSPADVAHEHLKERGLFGLAAPGTNPSDYYHQMTLMASHPAPYGDLLMQSGGAAGAPHLHDYLNPADASRFSSPRVTPRLSRKRALSISPLSDASLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQILSQQRGLGSAFGHTPPLIQPSPTFLTQQPMALTSISTMPTQLSSNSSNCLNDANQNKQSSESAVSSTVNPITIHKRSKVKTEAEGLRSASPLGLTQEQLADLKEDLDRDDCKQEAEVVIYETNCHWADCTKEYDTQEQLVHHINNEHIHGEKKEFVCRWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPDAHVTKKQRNDVHLRAPLLKENGDNEASAEPGGQGSEDSVEASSTSHTVEDCLHIKAIKTESSGLCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALEDTSPGADTSALAAPATGGLQLRKHMTTMHRFEQLKREKLKSLKDSCSWAGPAPHTRNTKLPPLPANGSVLESFNGTGGGGPAGLLPNQRLPELTEVTMLSQLQERRDSSTSTVSSAYTVSRRSSGISPYFSSRRSSEASPLGAGRPHNASSADSYDPISTDASRRSSEASQCSGGGPGLLNLTPAQQYSLRAKYAAATGGPPPTPLPGLERVSLRTRLALLDAPERALPGACPHPLGPRRGSDGPAYSHGHGHGYVGAAPAFPHEGPGSSMRRASDPVRRPDPLILPRVQRFHSTHNMNPGSLPPCTDRRGPHLQSHPSVDSSLTRNTYSPRPPSISENVMMEAIAAGVDGTGLESDLGLVEDELVLPDDVVQYIKAHTSGALDDSTRQGYPTESTGFPENSKLPSPGLQGHRRLAAADSNMSPSAPGLGGCQLSYSPSSNLNKSNMPVQWNEVSSGTMDALPSQVKPPPFPHSNLAVVQQKPAFGQYSGYSPQALQASSGGLDSTQPHLQLRGAPAAPRGSYTQQPRQPATGGQCLSVTAAMSPQASYSQAHPQLSPNIVSGPLNQFSPSCSNMAAKPSHLGLPPQMEVVPNATMMSGHQRELGVANSSLPGVSQPHAVLSYPQQEGYQQGSSLLSSHQPSFMESQQGTGFGLMQPRPPLEPNTASRHRRVHAGQQQLYARTASQAMVTSANQETAEAMPKGTAGTMVSLAPQPSQDTGRSQDQNTLYYYGQIHMYEQNGDCPAMQPQPPQPQACSDNIQPQPLPSPGVNQVSSTVDSQLLEAPQIDFDAIMDDGDHSSLFSGALSPTLLHNLSQNSSRLTTPRNSLTLPSIPAGISNMAVGDMSSMLTSLAEENKFLNMMT", "length": 1427, "header": "tr|A0A9J7H1F5-1|A0A9J7H1F5_CRIGR Computationally mapped isoform of Zinc finger protein GLI2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Gli2 PE=3 SV=1 CANONICAL=A0A9J7G1B0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 223, "start_aa": "Thr", "end_pos": 223, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr223", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 888, "start_aa": "Thr", "end_pos": 888, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr888", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757572", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757572", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "forebrain development", "id": "GO:0030900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030900", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "lung development", "id": "GO:0030324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030324", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "proximal/distal pattern formation", "id": "GO:0009954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009954", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" }, { "name": "embryonic organ morphogenesis", "id": "GO:0048562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048562", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1105, "end_pos": 1107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1127, "end_pos": 1129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1277, "end_pos": 1279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1292, "end_pos": 1294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1497, "end_pos": 1499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1501, "end_pos": 1503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273871" } ] }, { "annotation": "Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1C4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1C4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G1C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1C4" }, { "id": "PS51352", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51352" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thioredoxin", "eco_id": "ECO_0000259", "start_pos": 214, "end_pos": 327, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273534" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Thsd7b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3", "locus": {} } ], "crossref": [ { "id": "100771852", "url": "https://www.ncbi.nlm.nih.gov/gene/100771852", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771852", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771852", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G1F3", "url": "https://www.orthodb.org/?gene=A0A9J7G1F3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11311", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11311", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11311:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11311:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23308", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23308", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273534", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G1F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFPRSDLAVTHWVLRSMRKLFLVFSLLLSQAAHLEGRKDSQFIWKTGPWGRCAGDCGPGGAQSRAVWCFHIEGWTSPMSNCDESTRPPRERSCFRVCDWHSDLFQWEVSDWHRCLLAPGAQGEPRPRASECVTAQHGLQHRTVRCLQKINRTMVANEICEHFAPLPPTEQACLIPCPRDCVVSEFSPWSTCREGCGKRLQHRTRVAIAPPLYGGLQCPNLTESRACEAPVSCPLGKEEYSFSLKVGPWSKCRLPHLKEVNLSGRNVQDFSSDSNEQVTLTHQSYKAHHHSQPGGVEIGFQTRQVWCTRSDGRNALLSLCMQDSFPLTVQPCVMPKDCETSEWSPWSPCSKTCRSGSLSPGVRSRSRNVKHIAIGGGQECPELLEKETCIAEAELLQPCPRYSWRTSEWKECQVSLLLEQQDPLWHDTGPVCGGGIQTREVYCAQSLPAAASSRAKEVSRPVESTLCLGPAPSASQLCNVPCSMACIVSSWSSWGPCVHDNCHDPQGKKGFRMRQRHVLMESTGPTGHCPHLVESVPCEDPMCYRWLASEGICIPDHGKCGLGHRILKAVCQNERGEEVSGSLCPVPPPPERMACDIPCRMDCVVSEWTVWSSCSQSCSNKNADGKQSRSRSLLALAGEGGKPCPSSQELQEYRLCNDHSCTQLYWETSAWGPCSENTLVTAFNVTIGWNGEATCGVGIQTRRVFCIKSHVGQVMTKRCPESTRPETVRPCFLPCKKDCLVTAFSEWTPCPHLCQPGNTTIKQSRYRIIIQEAANGGQECPDTLFEERDCEDISLCPTYRWKLQKWSPCILVPESVRQGRTGTSEACGKGLQTRAVSCISDDNQSAEMTECLKQMNGMPPLVQECTIPCREDCTFTPWSKFTPCSKNCEATQIRRRQLTGKSRKREKCQDAALYPLVEMEPCPCDAFMSHPYGNWSACILPESKRDPQRGGLWVQGAGKECGKGVRFRAIACSDKNGRPVDPSFCNSSGYVQEECVIPCPFDCKLSDWSSWGSCSSSCGIGVRIRSKWLKEKPYSGGRPCPKLDLKNQVHEAVPCYSECNQYSWVVEHWSPCQINNELRSPRCGRGTQSRRIRCVSTADSEGGTVDRNLCNQDDAPPETQACSLLCPSECVMSEWGTWSKCPQSCDPHATQRRSRHLLRPSLNSRTCGEDSQVRPCLLNENCFQFQYNLTEWSTCQLSENASCGQGVRTRLLSCVRSDGKPVGMDHCEQRNLEKPQRMSIPCLVECVANCQLSGWSAWTECSQTCGQGGRMSRTRFIIMPTQGEGRQCPTELTQQKPCPVMPCYSWVLGNWSACKLEGGDCGEGVQVRSFSCVVHNGSISHTAVHVGDALCGEVPFQEGILKQLCSVPCPGDCHITPWSEWSKCELTCIDGRSLETTGRQSRSRTFIVQSFENQDSCPQQVLETRPCAGGKCYHYTWKASLWNNNERTVWCQRSDGLNVTGGCSPQARPAAIRQCIPACRKPFSYCTQGGVCGCEKGYTEIMRSSGFLDYCMKVPGSEDKKADVKNLPGKNRPVNSKIHDIFKGWSLQPLDPDGRVKIWVYGVSGGSFLMMIFLVFTSYLVCKKPKPHQSTPRHQKPLTLAYDGDLDM", "length": 1607, "header": "tr|A0A9J7G1F3-1|A0A9J7G1F3_CRIGR Isoform 1 of Thrombospondin type-1 domain-containing protein 7B OS=Cricetulus griseus OX=10029 GN=Thsd7b PE=4 SV=1 CANONICAL=A0A9J7G1F3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G1F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3/entry#A0A9J7G1F3-1", "sequence": { "sequence": "MFPRSDLAVTHWVLRSMRKLFLVFSLLLSQAAHLEGRKDSQFIWKTGPWGRCAGDCGPGGAQSRAVWCFHIEGWTSPMSNCDESTRPPRERSCFRVCDWHSDLFQWEVSDWHRCLLAPGAQGEPRPRASECVTAQHGLQHRTVRCLQKINRTMVANEICEHFAPLPPTEQACLIPCPRDCVVSEFSPWSTCREGCGKRLQHRTRVAIAPPLYGGLQCPNLTESRACEAPVSCPLGKEEYSFSLKVGPWSKCRLPHLKEVNLSGRNVQDFSSDSNEQVTLTHQSYKAHHHSQPGGVEIGFQTRQVWCTRSDGRNALLSLCMQDSFPLTVQPCVMPKDCETSEWSPWSPCSKTCRSGSLSPGVRSRSRNVKHIAIGGGQECPELLEKETCIAEAELLQPCPRYSWRTSEWKECQVSLLLEQQDPLWHDTGPVCGGGIQTREVYCAQSLPAAASSRAKEVSRPVESTLCLGPAPSASQLCNVPCSMACIVSSWSSWGPCVHDNCHDPQGKKGFRMRQRHVLMESTGPTGHCPHLVESVPCEDPMCYRWLASEGICIPDHGKCGLGHRILKAVCQNERGEEVSGSLCPVPPPPERMACDIPCRMDCVVSEWTVWSSCSQSCSNKNADGKQSRSRSLLALAGEGGKPCPSSQELQEYRLCNDHSCTQLYWETSAWGPCSENTLVTAFNVTIGWNGEATCGVGIQTRRVFCIKSHVGQVMTKRCPESTRPETVRPCFLPCKKDCLVTAFSEWTPCPHLCQPGNTTIKQSRYRIIIQEAANGGQECPDTLFEERDCEDISLCPTYRWKLQKWSPCILVPESVRQGRTGTSEACGKGLQTRAVSCISDDNQSAEMTECLKQMNGMPPLVQECTIPCREDCTFTPWSKFTPCSKNCEATQIRRRQLTGKSRKREKCQDAALYPLVEMEPCPCDAFMSHPYGNWSACILPESKRDPQRGGLWVQGAGKECGKGVRFRAIACSDKNGRPVDPSFCNSSGYVQEECVIPCPFDCKLSDWSSWGSCSSSCGIGVRIRSKWLKEKPYSGGRPCPKLDLKNQVHEAVPCYSECNQYSWVVEHWSPCQINNELRSPRCGRGTQSRRIRCVSTADSEGGTVDRNLCNQDDAPPETQACSLLCPSECVMSEWGTWSKCPQSCDPHATQRRSRHLLRPSLNSRTCGEDSQVRPCLLNENCFQFQYNLTEWSTCQLSENASCGQGVRTRLLSCVRSDGKPVGMDHCEQRNLEKPQRMSIPCLVECVANCQLSGWSAWTECSQTCGQGGRMSRTRFIIMPTQGEGRQCPTELTQQKPCPVMPCYSWVLGNWSACKLEGGDCGEGVQVRSFSCVVHNGSISHTAVHVGDALCGEVPFQEGILKQLCSVPCPGDCHITPWSEWSKCELTCIDGRSLETTGRQSRSRTFIVQSFENQDSCPQQVLETRPCAGGKCYHYTWKASLWNNNERTVWCQRSDGLNVTGGCSPQARPAAIRQCIPACRKPFSYCTQGGVCGCEKGYTEIMRSSGFLDYCMKVPGSEDKKADVKNLPGKNRPVNSKIHDIFKGWSLQPLDPDGRVKIWVYGVSGGSFLMMIFLVFTSYLVCKKPKPHQSTPRHQKPLTLAYDGDLDM", "length": 1607, "header": "tr|A0A9J7G1F3-1|A0A9J7G1F3_CRIGR Isoform 1 of Thrombospondin type-1 domain-containing protein 7B OS=Cricetulus griseus OX=10029 GN=Thsd7b PE=4 SV=1 CANONICAL=A0A9J7G1F3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1280, "start_aa": "Thr", "end_pos": 1280, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1280", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771852", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771852", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1187, "end_pos": 1189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1199, "end_pos": 1201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1309, "end_pos": 1311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1335, "end_pos": 1337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1457, "end_pos": 1459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 683, "end_pos": 685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 757, "end_pos": 759, "annotation": "n_glycosylation_sequon" }, { "start_pos": 842, "end_pos": 844, "annotation": "n_glycosylation_sequon" }, { "start_pos": 933, "end_pos": 935, "annotation": "n_glycosylation_sequon" }, { "start_pos": 985, "end_pos": 987, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G1F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3" }, { "id": "PF19028", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spondin-like TSP1", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 229, "start_aa": "Cys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G1F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1F3" }, { "id": "PF23308", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23308" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thrombospondin type-1", "eco_id": "ECO_0000259", "start_pos": 1476, "end_pos": 1515, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1280 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1187, "end_pos": 1189 }, { "start_pos": 1199, "end_pos": 1201 }, { "start_pos": 1309, "end_pos": 1311 }, { "start_pos": 1335, "end_pos": 1337 }, { "start_pos": 1457, "end_pos": 1459 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 683, "end_pos": 685 }, { "start_pos": 757, "end_pos": 759 }, { "start_pos": 842, "end_pos": 844 }, { "start_pos": 933, "end_pos": 935 }, { "start_pos": 985, "end_pos": 987 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G1K1-1", "uniprot_ac": "A0A9J7G1K1", "uniprot_id": "A0A9J7G1K1_CRIGR", "mass": { "chemical_mass": 39821.0, "monoisotopic_mass": 39821.0 }, "refseq": { "ac": "XP_027272185", "name": "solute carrier family 25 member 47 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272185" }, "gene_names": [ { "name": "Slc25a47", "type": "recommended", "evidence": [ { "id": "A0A9J7G1K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1" } ] }, { "name": "Slc25a47", "type": "synonym", "evidence": [ { "id": "XP_027272185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272185" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 47", "type": "recommended", "evidence": [ { "id": "A0A9J7G1K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1/entry#names_and_taxonomy" } ] }, { "name": "Hepatocellular carcinoma down-regulated mitochondrial carrier homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7G1K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1/entry#names_and_taxonomy" } ] }, { "name": "Mitochondrial NAD(+) transporter SLC25A47", "type": "synonym", "evidence": [ { "id": "A0A9J7G1K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 25 member 47 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027272185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272185" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027272185.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272185" } ] }, { "annotation": "Mitochondrial NAD(+) transporter that acts as a 'metabolic gate' in hepatic lipogenesis. Provides NAD(+) substrate to mitochondrial SIRT3 deacetylase and enables its NAD(+)-dependent activities in mitochondrial energy metabolism. This triggers downstream activation of PRKAA1/AMPK-alpha signaling cascade that negatively regulates sterol regulatory element-binding protein (SREBP) transcriptional activities and ATP-consuming lipogenesis to restore cellular energy balance. May transport other mitochondrial metabolites having an aromatic nucleotide and phosphate groups, such as acetyl-CoA. Does not transport amino acids. The transport mechanism remains to be elucidated.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1#function" }, { "database": "UniProtKB", "id": "ARBA00053322", "url": "https://www.uniprot.org/uniprotkb/ARBA00053322#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc25a47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1", "locus": {} } ], "crossref": [ { "id": "A0A9J7G1K1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G1K1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100771881", "url": "https://www.ncbi.nlm.nih.gov/gene/100771881", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050567", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050567", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771881", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771881", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G1K1", "url": "https://www.orthodb.org/?gene=A0A9J7G1K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45624:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45624:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272185", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "65408", "url": "https://www.rhea-db.org/rhea/65408", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "75039", "url": "https://www.rhea-db.org/rhea/75039", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G1K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFRPRCVELRPSRSAGEGPISLLYLTCGIDRSWPVWHRERPESFPFPTLSMDFVAGAIGGVCGVAVGYPLDTVKVRIQTETKYTSIWHCIRDTYRQERVWGFYRGLSLPVCTVSLVSSVSFGTYHHCLAHLCRFRYGSTDAKPTKADITLSGCVSGLVRVFLTSPTEVAKVRLQTQAQAQTQQRRPSATWTSMAPALCPAPAACLEPRPAYRGPLHCLVTVAREEGLRGLYKGSSALLLREGHSFATYFLSYAMLCEWLTPAGHSRPDVLGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQQRYRGLLHCVVTSVREEGPRVLFKGLTLNCCRAFPVNMVVFVAYEAVLRLTRRLCT", "length": 361, "header": "tr|A0A9J7G1K1-1|A0A9J7G1K1_CRIGR Isoform 1 of Solute carrier family 25 member 47 OS=Cricetulus griseus OX=10029 GN=Slc25a47 PE=3 SV=1 CANONICAL=A0A9J7G1K1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G1K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1/entry#A0A9J7G1K1-1", "sequence": { "sequence": "MSFRPRCVELRPSRSAGEGPISLLYLTCGIDRSWPVWHRERPESFPFPTLSMDFVAGAIGGVCGVAVGYPLDTVKVRIQTETKYTSIWHCIRDTYRQERVWGFYRGLSLPVCTVSLVSSVSFGTYHHCLAHLCRFRYGSTDAKPTKADITLSGCVSGLVRVFLTSPTEVAKVRLQTQAQAQTQQRRPSATWTSMAPALCPAPAACLEPRPAYRGPLHCLVTVAREEGLRGLYKGSSALLLREGHSFATYFLSYAMLCEWLTPAGHSRPDVLGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQQRYRGLLHCVVTSVREEGPRVLFKGLTLNCCRAFPVNMVVFVAYEAVLRLTRRLCT", "length": 361, "header": "tr|A0A9J7G1K1-1|A0A9J7G1K1_CRIGR Isoform 1 of Solute carrier family 25 member 47 OS=Cricetulus griseus OX=10029 GN=Slc25a47 PE=3 SV=1 CANONICAL=A0A9J7G1K1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771881", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771881", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "65408", "name": "", "equation": "NAD(+)(in) = NAD(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "65408", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/65408" } ] }, { "id": "75039", "name": "", "equation": "acetyl-CoA(in) = acetyl-CoA(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "75039", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/75039" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G1L8-1", "uniprot_ac": "A0A9J7G1L8", "uniprot_id": "A0A9J7G1L8_CRIGR", "mass": { "chemical_mass": 81761.0, "monoisotopic_mass": 81761.0 }, "refseq": { "ac": "XP_027273606", "name": "band 4.1-like protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273606" }, "gene_names": [ { "name": "Epb41l5", "type": "recommended", "evidence": [ { "id": "A0A9J7G1L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ] }, { "name": "Epb41l5", "type": "synonym", "evidence": [ { "id": "XP_027273606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273606" } ] } ], "protein_names": [ { "name": "Band 4.1-like protein 5", "type": "recommended", "evidence": [ { "id": "A0A9J7G1L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8/entry#names_and_taxonomy" } ] }, { "name": "Erythrocyte membrane protein band 4.1-like 5", "type": "synonym", "evidence": [ { "id": "A0A9J7G1L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8/entry#names_and_taxonomy" } ] }, { "name": "band 4.1-like protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027273606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273606" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273606" } ] }, { "annotation": "Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8#function" }, { "database": "UniProtKB", "id": "ARBA00023750", "url": "https://www.uniprot.org/uniprotkb/ARBA00023750#function" }, { "database": "UniProtKB", "id": "A0A9J7G3D1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D1#function" }, { "database": "UniProtKB", "id": "A0A9J7G4K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4K4#function" }, { "database": "UniProtKB", "id": "A0A9J7JSR9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSR9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Epb41l5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8", "locus": {} } ], "crossref": [ { "id": "cd13186", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13186", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14473", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14473", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17205", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17205", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757297", "url": "https://www.ncbi.nlm.nih.gov/gene/100757297", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000798", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000798", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757297", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757297", "database": "KEGG 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"id": "PF09380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273606", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3D1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSR9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRFLRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDAKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLRQDILSGKLECPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKASTTKPDDLGVHYASAQNNDAQQAWGVRSPVPMNPSSSSGPVLVEIENLSQNSAADQHDRKCLPLNVDLLNSPDLLETTIGDVTRTSDTWETSPAPDDINVITRSNELEEPKVECEILKDDTEKLKQLEMEQNILPSPRPPVVDINVNSQEEVVKLTEKCLNNAIESPGLNAVRVPPDFKSNILKAQVEAVHKAAREDSLTHKNASVQEAATNSTVSNENNVPLCKDSLTLVHATAADSESVLKDATDELDALLLSLTENLMDHTVTPQVSSSSMITPRWIIPQSAAISSRLAGCGKSVAGAEGCATKDAYSLISPPAPFLVDAVTSSAPLAEDPALKQKCLLTTEL", "length": 730, "header": "tr|A0A9J7G1L8-1|A0A9J7G1L8_CRIGR Isoform 1 of Band 4.1-like protein 5 OS=Cricetulus griseus OX=10029 GN=Epb41l5 PE=4 SV=1 CANONICAL=A0A9J7G1L8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G1L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8/entry#A0A9J7G1L8-1", "sequence": { "sequence": "MLRFLRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDAKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLRQDILSGKLECPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKASTTKPDDLGVHYASAQNNDAQQAWGVRSPVPMNPSSSSGPVLVEIENLSQNSAADQHDRKCLPLNVDLLNSPDLLETTIGDVTRTSDTWETSPAPDDINVITRSNELEEPKVECEILKDDTEKLKQLEMEQNILPSPRPPVVDINVNSQEEVVKLTEKCLNNAIESPGLNAVRVPPDFKSNILKAQVEAVHKAAREDSLTHKNASVQEAATNSTVSNENNVPLCKDSLTLVHATAADSESVLKDATDELDALLLSLTENLMDHTVTPQVSSSSMITPRWIIPQSAAISSRLAGCGKSVAGAEGCATKDAYSLISPPAPFLVDAVTSSAPLAEDPALKQKCLLTTEL", "length": 730, "header": "tr|A0A9J7G1L8-1|A0A9J7G1L8_CRIGR Isoform 1 of Band 4.1-like protein 5 OS=Cricetulus griseus OX=10029 GN=Epb41l5 PE=4 SV=1 CANONICAL=A0A9J7G1L8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8/entry#A0A9J7G3D1-1", "sequence": { "sequence": "MLRFLRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDAKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLRQDILSGKLECPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKASTTKPDDLGVHYASAQNNDAQQAWGVRSPVPMNPSSSSGPVLVEIENLSQNSAADQHDRKWLSATSDCCQRGGNQWSTRALSPPQTAHRNYTDFVLEHNVKNAGVHHDAHFSGRAAMTEI", "length": 504, "header": "tr|A0A9J7G3D1-1|A0A9J7G3D1_CRIGR Computationally mapped isoform of Band 4.1-like protein 5 OS=Cricetulus griseus OX=10029 GN=Epb41l5 PE=4 SV=1 CANONICAL=A0A9J7G1L8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8/entry#A0A9J7G4K4-1", "sequence": { "sequence": "MLRFLRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDAKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLRQDILSGKLECPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKASTTKPDDLGVHYASAQNNDAQQAWGVRSPVPMNPSSSSGPVLVEIENLSQNSAADQHDRKCLPLNVDLLNSPDLLETTIGDVTRTSDTWETSPAPDDINVITRSNELEEPKVECEILKDDTEKLKQLEMEQNILPSPRPPVVDINVNSQEEVVKLTEKCLNNAIESPGLNAVRVPPDFKSNILKAQVEAVHKAAREDSLTHKNASVQEAATNSTVSNENNVPLCKDSLTLVHATAADSESVLKDATDELDALLLSLTENLMDHTVTPQVSSSSMITPRWIIPSAAISSRLAGCGKSVAGAEGCATKDAYSLISPPAPFLVDAVTSSAPLAEDPALKQKCLLTTEL", "length": 729, "header": "tr|A0A9J7G4K4-1|A0A9J7G4K4_CRIGR Computationally mapped isoform of Band 4.1-like protein 5 OS=Cricetulus griseus OX=10029 GN=Epb41l5 PE=4 SV=1 CANONICAL=A0A9J7G1L8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8/entry#A0A9J7JSR9-1", "sequence": { "sequence": "MLRFLRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDAKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLRQDILSGKLECPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGETKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKASTTKPDDLGLPLNVDLLNSPDLLETTIGDVTRTSDTWETSPAPDDINVITRSNELEEPKVECEILKDDTEKLKQLEMEQNILPSPRPPVVDINVNSQEEVVKLTEKCLNNAIESPGLNAVRVPPDFKSNILKAQVEAVHKAAREDSLTHKNASVQEAATNSTVSNENNVPLCKDSLTLVHATAADSESVLKDATDELDALLLSLTENLMDHTVTPQVSSSSMITPRWIIPQSAAISSRLAGCGKSVAGAEGCATKDAYSLISPPAPFLVDAVTSSAPLAEDPALKQKCLLTTEL", "length": 678, "header": "tr|A0A9J7JSR9-1|A0A9J7JSR9_CRIGR Computationally mapped isoform of Band 4.1-like protein 5 OS=Cricetulus griseus OX=10029 GN=Epb41l5 PE=4 SV=1 CANONICAL=A0A9J7G1L8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757297", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757297", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ], "pmid": "" }, { "name": "photoreceptor inner segment", "id": "GO:0001917", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001917", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "actomyosin structure organization", "id": "GO:0031032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031032", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytoskeletal protein binding", "id": "GO:0008092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008092", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 587, "end_pos": 589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G1L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L8" }, { "id": "PS50057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FERM", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 327, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 431, "end_pos": 433 }, { "start_pos": 587, "end_pos": 589 }, { "start_pos": 596, "end_pos": 598 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G1M1-1", "uniprot_ac": "A0A9J7G1M1", "uniprot_id": "A0A9J7G1M1_CRIGR", "mass": { "chemical_mass": 13676.0, "monoisotopic_mass": 13676.0 }, "refseq": { "ac": "XP_027273909", "name": "histone H2A.Z isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273909" }, "gene_names": [ { "name": "LOC100754667", "type": "recommended", "evidence": [ { "id": "A0A9J7G1M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1M1" } ] }, { "name": "LOC100754667", "type": "synonym", "evidence": [ { "id": "XP_027273909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273909" } ] } ], "protein_names": [ { "name": "Histone H2A", "type": "recommended", "evidence": [ { "id": "A0A9J7G1M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1M1/entry#names_and_taxonomy" } ] }, { "name": "histone H2A.Z isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027273909", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273909" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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"MKVITCEIAWHNKEPVYSLDFQHAAAWKSHRLASAGVDTAVRIWKVEKGPDGKAVVEFLSNLARHTRAVNVVRFSPSGEILASGGDDAVVLLWRMNDNKEPEPITFQDEDEAQLNKENWTVIKTLRGHLEDVCDICWANDGTLMASASVDNTVIIWDASKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRVYSTQKKRVAFNISKMLSGPGSEGEARSFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCVESGENVTNTTYVFSRKHLKRPIAHLPCPGKATLAVRCCPVYFELRPVPETERASEEPSPELVSLPYRMVFAVASEDSVVLYDTQQPFPFGYVSNIHYHTLSDISWSSDGTFLGISSTDGYCSFVTFEKGELGIPLKEKPVLNIRTPDTAKKTKSQTHQGSSPGPRSAEGTPTCRLQDPSSPSTTPSPTTQSPAPSAIKDSPSATPAGKSPLPRPPEEKTLQPASQNTKAPQPQRVTLNTLQFWGKTPPRRINLTPLKADTAPSPLPTGGTTTPSTEETEPGTQMEETVLLASDLCNTQPQLEDLDHFYPPESQAARLVSTLPLASLSSVRPPGPCNCLSDFQLEWGVLASLSLRRLFSGQALCSPCLWPKATTKGELRGVVREPGGRSYFLAYSSWLAQPASYRSQDHPPRDGTAHHGLGPPPQSLIKKMLAYSQIFQRHFLN", "length": 699, "header": "tr|A0A9J7G1Q4-1|A0A9J7G1Q4_CRIGR Isoform 1 of Chromatin assembly factor 1 subunit B OS=Cricetulus griseus OX=10029 GN=Chaf1b PE=3 SV=1 CANONICAL=A0A9J7G1Q4-1" }, "isoforms": [ { "isoform_ac": "A0A061I7A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4/entry#A0A061I7A8-1", "sequence": { "sequence": "MKVITCEIAWHNKEPVYSLDFQHAAAWKSHRLASAGVDTAVRIWKVEKGPDGKAVVEFLSNLARHTRAVNVVRFSPSGEILASGGDDAVVLLWRMNDNKEPEPITFQDEDEAQLNKENWTVIKTLRGHLEDVCDICWANDGTLMASASVDNTVIIWDASKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRVYSTQKKRVAFNISKMLSGPGSEGEARSFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCVESGENVTNTTYVFSRKHLKRPIAHLPCPGKATLAVRCCPVYFELRPVPETERASEEPSPELVSLPYRMVFAVASEDSVVLYDTQQPFPFGYVSNIHYHTLSDISWSSDGTFLGISSTDGYCSFVTFEKGELGIPLKEKPVLNIRTPDTAKKTKSQTHQGSSPGPRSAEGTPTCRLQDPSSPSTTPSPTTQSPAPSAIKDSPSATPAGKSPLPRPPEEKTLQPASQNTKAPQPQRVTLNTLQFWGKTPPRRINLTPLKADTAPSPLPTGGTTTPSTEETEPVMPGKPQGEPPELKRPRLQDQEGGAQTLGSDEASKSA", "length": 573, "header": "tr|A0A061I7A8-1|A0A061I7A8_CRIGR Computationally mapped isoform of Chromatin assembly factor 1 subunit B OS=Cricetulus griseus OX=10029 GN=Chaf1b PE=3 SV=1 CANONICAL=A0A9J7G1Q4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4/entry#A0A9J7G1Q4-1", "sequence": { "sequence": "MKVITCEIAWHNKEPVYSLDFQHAAAWKSHRLASAGVDTAVRIWKVEKGPDGKAVVEFLSNLARHTRAVNVVRFSPSGEILASGGDDAVVLLWRMNDNKEPEPITFQDEDEAQLNKENWTVIKTLRGHLEDVCDICWANDGTLMASASVDNTVIIWDASKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRVYSTQKKRVAFNISKMLSGPGSEGEARSFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCVESGENVTNTTYVFSRKHLKRPIAHLPCPGKATLAVRCCPVYFELRPVPETERASEEPSPELVSLPYRMVFAVASEDSVVLYDTQQPFPFGYVSNIHYHTLSDISWSSDGTFLGISSTDGYCSFVTFEKGELGIPLKEKPVLNIRTPDTAKKTKSQTHQGSSPGPRSAEGTPTCRLQDPSSPSTTPSPTTQSPAPSAIKDSPSATPAGKSPLPRPPEEKTLQPASQNTKAPQPQRVTLNTLQFWGKTPPRRINLTPLKADTAPSPLPTGGTTTPSTEETEPGTQMEETVLLASDLCNTQPQLEDLDHFYPPESQAARLVSTLPLASLSSVRPPGPCNCLSDFQLEWGVLASLSLRRLFSGQALCSPCLWPKATTKGELRGVVREPGGRSYFLAYSSWLAQPASYRSQDHPPRDGTAHHGLGPPPQSLIKKMLAYSQIFQRHFLN", "length": 699, "header": "tr|A0A9J7G1Q4-1|A0A9J7G1Q4_CRIGR Isoform 1 of Chromatin assembly factor 1 subunit B OS=Cricetulus griseus OX=10029 GN=Chaf1b PE=3 SV=1 CANONICAL=A0A9J7G1Q4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GY43-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4/entry#A0A9J7GY43-1", "sequence": { "sequence": "MKVITCEIAWHNKEPVYSLDFQHAAAWKSHRLASAGVDTAVRIWKVEKGPDGKAVVEFLSNLARHTRAVNVVRFSPSGEILASGGDDAVVLLWRMNDNKEPEPITFQDEDEAQLNKENWTVIKTLRGHLEDVCDICWANDGTLMASASVDNTVIIWDASKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRVYSTQKKRVAFNISKMLSGPGSEGEARSFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCVESGENVTNTTYVFSRKHLKRPIAHLPCPGKATLAVRCCPVYFELRPVPETERASEEPSPELVSLPYRMVFAVASEDSVVLYDTQQPFPFGYVSNIHYHTLSDISWSSDGTFLGISSTDGYCSFVTFEKGELGIPLKEKPVLNIRTPDTAKKTKSQTHQGSSPGPRSAEGTPTCRLQDPSSPSTTPSPTTQSPAPSAIKDSPSATPAGKSPLPRPPEEKTLQPASQNTKAPQPQRVTLNTLQFWGKTPPRRINLTPLKADTAPSPLPTGGTTTPSTEETEPGTQMEETVLLASDLCNTQPQLEDLDHFYPPESQAARLVSTLPLASLSSVRPPGPCNCLSDFQLEWGVLASLSLRRLFSGQALCSPCLWPKATTKGPPRSIQLKTGKVMARSWNSHPR", "length": 653, "header": "tr|A0A9J7GY43-1|A0A9J7GY43_CRIGR Computationally mapped isoform of Chromatin assembly factor 1 subunit B OS=Cricetulus griseus OX=10029 GN=Chaf1b PE=3 SV=1 CANONICAL=A0A9J7G1Q4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 440, "start_aa": "Thr", "end_pos": 440, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr440", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 460, "start_aa": "Thr", "end_pos": 460, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr460", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751472", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" } ], "pmid": "" }, { "name": "CAF-1 complex", "id": "GO:0033186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033186", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" } ], "pmid": "" }, { "name": "nucleosome assembly", "id": "GO:0006334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006334", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" } ], "pmid": "" }, { "name": "DNA replication-dependent chromatin assembly", "id": "GO:0006335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006335", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G1Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" }, { "id": "PF24105", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CAF1B/HIR1 beta-propeller", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 387, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G1Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q4" }, { "id": "PF15512", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15512" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chromatin assembly factor 1 subunit B C-terminal", "eco_id": "ECO_0000259", "start_pos": 417, "end_pos": 537, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 440, 460 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 508, "end_pos": 510 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G1Q9-1", "uniprot_ac": "A0A9J7G1Q9", "uniprot_id": "A0A9J7G1Q9_CRIGR", "mass": { "chemical_mass": 78425.0, "monoisotopic_mass": 78425.0 }, "refseq": { "ac": "XP_027273755", "name": "neutral and basic amino acid transport protein rBAT", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273755" }, "gene_names": [ { "name": "Slc3a1", "type": "recommended", "evidence": [ { "id": "A0A9J7G1Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q9" } ] }, { "name": "Slc3a1", "type": "synonym", "evidence": [ { "id": "XP_027273755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273755" } ] } ], "protein_names": [ { "name": "Amino acid transporter heavy chain SLC3A1", "type": "recommended", "evidence": [ { "id": "A0A9J7G1Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q9/entry#names_and_taxonomy" } ] }, { "name": "D2", "type": "synonym", "evidence": [ { "id": "A0A9J7G1Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q9/entry#names_and_taxonomy" } ] }, { "name": "Neutral and basic amino acid transport protein", "type": "synonym", "evidence": [ { "id": "A0A9J7G1Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q9/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 3 member 1", "type": "synonym", "evidence": [ { "id": "A0A9J7G1Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q9/entry#names_and_taxonomy" } ] }, { "name": "b(0,+)-type amino acid transporter-related heavy chain", "type": "synonym", "evidence": [ { "id": "A0A9J7G1Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Q9/entry#names_and_taxonomy" } ] }, { "name": "neutral and basic amino acid transport protein rBAT", "type": "synonym", "evidence": [ { "id": "XP_027273755", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273755" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF27974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273983", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273983", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G1R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1X1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G223", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G223", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G223-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G223-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3T3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEVEQDQHEARLKELFDSFDTLGTGSLGQEELTDLCHVLSLEDVAPVLQQTLLQDNLLGRVHFDQFKEALILILSRTLSSEEHFQESEAQPKYVKGGKRYGRRSLPEFQESVEEFAEVTVLEPLDEEAKPSHIPSGDCNEHWKTQHSEEYEAKGQLRFWNPDDLNASHSGSCPPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGAMLEEVFLSLDPDGTMSVEDFFYGLFKTGKSLAPSASTPYRQLKRHLSMQSFDESGRRTTTSSAMTSTIGFRVFSCLDDGMGQASVERILDAWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNECNLRKLDEEYKERIAALKNELRQEREQILQQVSKQRAELEREIEKAKTEENYIRDRLALSLKENHRLENELLENAAKLAEYESLTNKLQHNLENVLAEKFGDLDPSSAEFFLQEERLVQMRNEYEQQCRLLQDQVDELHSELEEYRAQGKVFRLPLKNSLSEELDVNSGGIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEEKVYHYEKQLDETRVTCEKEQAAMKQKYEHGMHTLETQISDLRGEIADLQGQAMVLKEAHHEASCRHEEEKKQLQLMFEEEKTQLQEELRLEHERELKARLQQAEENFEQEREELSRSAAWTEEKVRGLTQDLEQSYQEQLLSLVEKHTLEKEELRKELLERHQRELQEGREKMETECNRRASQIEAQFQADCEKVTERCEHTLQSLEGRYRQELKDLLDQHLEERSQWQFEKDELTQECTEAQEQLKEALQREKATALVLNQEREMLEKTYKERLSSLSMERDQLLQDLEDLRNTSESQQGLLSDQILELKRSQERQLRERELCQTGTSEQLASQWLERLQVEREQERGEMVGKLAALESAHRVSCERADLEKAELSAEIRRLQNTVKDMQQAASLSGLQGAHSLVMTGEEAEGNGAMSLLQQGEQLLEENGDVLISLQRAHERAVKENAKMATEISRLQQRLKKLEPGSVMSPCLEEHIIEISGSSREQAESFLSQVKQGESSTTKHILSDLGDCEAQDLGSTGTSSVQRQECKTEELETSLECFSELENSEDTRTESWDLKSQVVQLQEQLTVLRADCDQASERKQDLLFDISVLKKKLKMLERIPETSSRYKLLYEDATRENACLHEELRLMEARYDESLDSNKELTTEVFRLQDEMKKMEEVMETFLSLEKSYDEVKMENEELSALVLRLQGKMEKVLDRAPLHCDSYSLWEAPSEHLEVISDEKLLEFRQTPGCTPKVMSMHHTLEERRQETKWCEQESTRLLARIKAHEIAWFHGTIQTHQEKPSVQNPVLLEESAALLGLQDTHPQHQVTIAELELEKQKLQELTRKLRERVSTLIKQRDAPSQGEKEEELKAMMHDLQITCSEMQRKVELLRYESEKLQEENSILRNEITTLNEEDTISNLKLEELNGSQEELWQKIETVEQEKASIQKMVEKLKKQVSDLKIKNQQLDSENTELSQKNSQNKEELQKLNQRLAEMLCQKKEPGACTSEKWEQENSSLREELDRCKVQTSTLVASLEAELSEVKLQTHIVEQENLLLKDELEKLKQLHRCPDLSDLQQKMASILTYNEQLLKEKEALSEELNSCADKLAKSSVLEHKIATMKQEQTTWEQQSESLKAQLVTSQEKVQDLEDVLQNVNLQMSRIQSDLQVTQQEKEALKQEVMSLRRQLQNAGDKVWISETADHLSGLHGQQKRLSWDKLDHFMDEEPQLLCEESKRLQTVVQNTKADLTHSLEKVRQLESNLLPIKHQKQLHQSCTVKPTEQEKLTLKRECEQSQKEQSPTSRKVSQMSSLERELETIHLENEGLRKKQVRLDEMQPPRSTVTLSPPSHWDLQLLQQQTCPMVPREQFLQLQQQLLQAEQKNQNLQEELDNRTSETNTPQGSQEHLVNLMEERMIEVEQKLKLVKRLLQEKVNQLKEQLCKNTKTDAMVKNLYVENAQLLKALEMTEQRQKTAEKKNYLLEEKIASLSTIVRNLAPAPLASTPPLRS", "length": 2122, "header": "tr|A0A9J7G1X1-1|A0A9J7G1X1_CRIGR Isoform 1 of Ninein isoform X3 OS=Cricetulus griseus OX=10029 GN=Nin PE=4 SV=1 CANONICAL=A0A9J7G1X1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G1R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1X1/entry#A0A9J7G1R0-1", "sequence": { "sequence": "MDEVEQDQHEARLKELFDSFDTLGTGSLGQEELTDLCHVLSLEDVAPVLQQTLLQDNLLGRVHFDQFKEALILILSRTLSSEEHFQESEAQPKYVKGGKRYGRRSLPEFQESVEEFAEVTVLEPLDEEAKPSHIPSGDCNEHWKTQHSEEYEAKGQLRFWNPDDLNASHSGSCPPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGAMLEEVFLSLDPDGTMSVEDFFYGLFKTGKSLAPSASTPYRQLKRHLSMQSFDESGRRTTTSSAMTSTIGFRVFSCLDDGMGQASVERILDAWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNECNLRKLDEEYKERIAALKNELRQEREQILQQVSKQRAELEREIEKAKTEENYIRDRLALSLKENHRLENELLENAAKLAEYESLTNKLQHNLENVLAEKFGDLDPSSAEFFLQEERLVQMRNEYEQQCRLLQDQVDELHSELEEYRAQGKVFRLPLKNSLSEELDVNSGGIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEEKVYHYEKQLDETRVTCEKEQAAMKQKYEHGMHTLETQISDLRGEIADLQGQAMVLKEAHHEASCRHEEEKKQLQLMFEEEKTQLQEELRLEHERELKARLQQAEENFEQEREELSRSAAWTEEKVRGLTQDLEQSYQEQLLSLVEKHTLEKEELRKELLERHQRELQEGREKMETECNRRASQIEAQFQADCEKVTERCEHTLQSLEGRYRQELKDLLDQHLEERSQWQFEKDELTQECTEAQEQLKEALQREKATALVLNQEREMLEKTYKERLSSLSMERDQLLQDLEDLRNTSESQQGLLSDQILELKRSQERQLRERELCQTGTSEQLASQWLERLQVEREQERGEMVGKLAALESAHRVSCERADLEKAELSAEIRRLQNTVKDMQQAASLSGLQGAHSLVMTGEEAEGNGAMSLLQQGEQLLEENGDVLISLQRAHERAVKENAKMATEISRLQQRLKKLEPGSVMSPCLEEHIIEISGSSREQAESFLSQVKQGESSTTKHILSDLGDCEAQDLGSTGTSSVQRQECKTEELETSLECFSELENSEDTRTESWDLKSQVVQLQEQLTVLRADCDQASERKQDLLFDISVLKKKLKMLERIPETSSRYKLLYEDATRENACLHEELRLMEARYDESLDSNKELTTEVFRLQDEMKKMEEVMETFLSLEKSYDEVKMENEELSALVLRLQGKMEKVLDRAPLHCDSYSLWEAPSEHLEVISDEKLLEFRQTPGCTPKVMSMHHTLEERRQETKWCEQESTRLLARIKAHEIAWFHGTIQTHQEKPSVQNPVLLEESAALLGLQDTHPQHQVTIAELELEKQKLQELTRKLRERVSTLIKQRDAPSQGEKEEELKAMMHDLQITCSEMQRKVELLRYESEKLQEENSILRNEITTLNEEDTISNLKLEELNGSQEELWQKIETVEQEKASIQKMVEKLKKQVSDLKIKNQQLDSENTELSQKNSQNKEELQKLNQRLAEMLCQKKEPGACTSEKWEQENSSLREELDRCKVQTSTLVASLEAELSEVKLQTHIVEQENLLLKDELEKLKQLHRCPDLSDLQQKMASILTYNEQLLKEKEALSEELNSCADKLAKSSVLEHKIATMKQEQTTWEQQSESLKAQLVTSQEKVQDLEDVLQNVNLQMSRIQSDLQVTQQEKEALKQEVMSLRRQLQNAGDKVWISETADHLSGLHGQQKRLSWDKLDHFMDEEPQLLCEESKRLQTVVQNTKADLTHSLEKVRQLESNLLPIKHQKQLHQSCTVKPTEQEKLTLKRECEQSQKEQSPTSRKVSQMSSLERELETIHLENEGLRKKQVRLDEMQPPRSTVTLSPPSHWDLQLLQQQTCPMVPREQFLQLQQQLLQAEQKNQNLQEELDNRTSETNTPQALLPEQRAVHTDSYRRIGHL", "length": 2035, "header": "tr|A0A9J7G1R0-1|A0A9J7G1X1_CRIGR Computationally mapped isoform of Ninein isoform X3 OS=Cricetulus griseus OX=10029 GN=Nin PE=4 SV=1 CANONICAL=A0A9J7G1X1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1X1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1X1/entry#A0A9J7G1X1-1", "sequence": { "sequence": "MDEVEQDQHEARLKELFDSFDTLGTGSLGQEELTDLCHVLSLEDVAPVLQQTLLQDNLLGRVHFDQFKEALILILSRTLSSEEHFQESEAQPKYVKGGKRYGRRSLPEFQESVEEFAEVTVLEPLDEEAKPSHIPSGDCNEHWKTQHSEEYEAKGQLRFWNPDDLNASHSGSCPPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGAMLEEVFLSLDPDGTMSVEDFFYGLFKTGKSLAPSASTPYRQLKRHLSMQSFDESGRRTTTSSAMTSTIGFRVFSCLDDGMGQASVERILDAWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNECNLRKLDEEYKERIAALKNELRQEREQILQQVSKQRAELEREIEKAKTEENYIRDRLALSLKENHRLENELLENAAKLAEYESLTNKLQHNLENVLAEKFGDLDPSSAEFFLQEERLVQMRNEYEQQCRLLQDQVDELHSELEEYRAQGKVFRLPLKNSLSEELDVNSGGIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEEKVYHYEKQLDETRVTCEKEQAAMKQKYEHGMHTLETQISDLRGEIADLQGQAMVLKEAHHEASCRHEEEKKQLQLMFEEEKTQLQEELRLEHERELKARLQQAEENFEQEREELSRSAAWTEEKVRGLTQDLEQSYQEQLLSLVEKHTLEKEELRKELLERHQRELQEGREKMETECNRRASQIEAQFQADCEKVTERCEHTLQSLEGRYRQELKDLLDQHLEERSQWQFEKDELTQECTEAQEQLKEALQREKATALVLNQEREMLEKTYKERLSSLSMERDQLLQDLEDLRNTSESQQGLLSDQILELKRSQERQLRERELCQTGTSEQLASQWLERLQVEREQERGEMVGKLAALESAHRVSCERADLEKAELSAEIRRLQNTVKDMQQAASLSGLQGAHSLVMTGEEAEGNGAMSLLQQGEQLLEENGDVLISLQRAHERAVKENAKMATEISRLQQRLKKLEPGSVMSPCLEEHIIEISGSSREQAESFLSQVKQGESSTTKHILSDLGDCEAQDLGSTGTSSVQRQECKTEELETSLECFSELENSEDTRTESWDLKSQVVQLQEQLTVLRADCDQASERKQDLLFDISVLKKKLKMLERIPETSSRYKLLYEDATRENACLHEELRLMEARYDESLDSNKELTTEVFRLQDEMKKMEEVMETFLSLEKSYDEVKMENEELSALVLRLQGKMEKVLDRAPLHCDSYSLWEAPSEHLEVISDEKLLEFRQTPGCTPKVMSMHHTLEERRQETKWCEQESTRLLARIKAHEIAWFHGTIQTHQEKPSVQNPVLLEESAALLGLQDTHPQHQVTIAELELEKQKLQELTRKLRERVSTLIKQRDAPSQGEKEEELKAMMHDLQITCSEMQRKVELLRYESEKLQEENSILRNEITTLNEEDTISNLKLEELNGSQEELWQKIETVEQEKASIQKMVEKLKKQVSDLKIKNQQLDSENTELSQKNSQNKEELQKLNQRLAEMLCQKKEPGACTSEKWEQENSSLREELDRCKVQTSTLVASLEAELSEVKLQTHIVEQENLLLKDELEKLKQLHRCPDLSDLQQKMASILTYNEQLLKEKEALSEELNSCADKLAKSSVLEHKIATMKQEQTTWEQQSESLKAQLVTSQEKVQDLEDVLQNVNLQMSRIQSDLQVTQQEKEALKQEVMSLRRQLQNAGDKVWISETADHLSGLHGQQKRLSWDKLDHFMDEEPQLLCEESKRLQTVVQNTKADLTHSLEKVRQLESNLLPIKHQKQLHQSCTVKPTEQEKLTLKRECEQSQKEQSPTSRKVSQMSSLERELETIHLENEGLRKKQVRLDEMQPPRSTVTLSPPSHWDLQLLQQQTCPMVPREQFLQLQQQLLQAEQKNQNLQEELDNRTSETNTPQGSQEHLVNLMEERMIEVEQKLKLVKRLLQEKVNQLKEQLCKNTKTDAMVKNLYVENAQLLKALEMTEQRQKTAEKKNYLLEEKIASLSTIVRNLAPAPLASTPPLRS", "length": 2122, "header": "tr|A0A9J7G1X1-1|A0A9J7G1X1_CRIGR Isoform 1 of Ninein isoform X3 OS=Cricetulus griseus OX=10029 GN=Nin PE=4 SV=1 CANONICAL=A0A9J7G1X1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G223-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1X1/entry#A0A9J7G223-1", "sequence": { "sequence": "MDEVEQDQHEARLKELFDSFDTLGTGSLGQEELTDLCHVLSLEDVAPVLQQTLLQDNLLGRVHFDQFKEALILILSRTLSSEEHFQESEAQPKYVKGGKRYGRRSLPEFQESVEEFAEVTVLEPLDEEAKPSHIPSGDCNEHWKTQHSEEYEAKGQLRFWNPDDLNASHSGSCPPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGAMLEEVFLSLDPDGTMSVEDFFYGLFKTGKSLAPSASTPYRQLKRHLSMQSFDESGRRTTTSSAMTSTIGFRVFSCLDDGMGQASVERILDAWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNECNLRKLDEEYKERIAALKNELRQEREQILQQVSKQRAELEREIEKAKTEENYIRDRLALSLKENHRLENELLENAAKLAEYESLTNKLQHNLENVLAEKFGDLDPSSAEFFLQEERLVQMRNEYEQQCRLLQDQVDELHSELEEYRAQGKVFRLPLKNSLSEELDVNSGGIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEEKVYHYEKQLDETRVTCEKEQAAMKQKYEHGMHTLETQISDLRGEIADLQGQAMVLKEAHHEASCRHEEEKKQLQLMFEEEKTQLQEELRLEHERELKARLQQAEENFEQEREELSRSAAWTEEKVRGLTQDLEQSYQEQLLSLVEKHTLEKEELRKELLERHQRELQEGRYESEKLQEENSILRNEITTLNEEDTISNLKLEELNGSQEELWQKIETVEQEKASIQKMVEKLKKQVSDLKIKNQQLDSENTELSQKNSQNKEELQKLNQRLAEMLCQKKEPGACTSEKWEQENSSLREELDRCKVQTSTLVASLEAELSEVKLQTHIVEQENLLLKDELEKLKQLHRCPDLSDLQQKMASILTYNEQLLKEKEALSEELNSCADKLAKSSVLEHKIATMKQEQTTWEQQSESLKAQLVTSQEKVQDLEDVLQNVNLQMSRIQSDLQVTQQEKEALKQEVMSLRRQLQNAGDKVWISETADHLSGLHGQQKRLSWDKLDHFMDEEPQLLCEESKRLQTVVQNTKADLTHSLEKVRQLESNLLPIKHQKQLHQSCTVKPTEQEKLTLKRECEQSQKEQSPTSRKVSQMSSLERELETIHLENEGLRKKQVRLDEMQPPRSTVTLSPPSHWDLQLLQQQTCPMVPREQFLQLQQQLLQAEQKNQNLQEELDNRTSETNTPQGSQEHLVNLMEERMIEVEQKLKLVKRLLQEKVNQLKEQLCKNTKTDAMVKNLYVENAQLLKALEMTEQRQKTAEKKNYLLEEKIASLSTIVRNLAPAPLASTPPLRS", "length": 1412, "header": "tr|A0A9J7G223-1|A0A9J7G223_CRIGR Computationally mapped isoform of Ninein isoform X6 OS=Cricetulus griseus OX=10029 GN=Nin PE=4 SV=1 CANONICAL=A0A9J7G1X1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1X1/entry#A0A9J7G3T3-1", "sequence": { "sequence": "MDEVEQDQHEARLKELFDSFDTLGTGSLGQEELTDLCHVLSLEDVAPVLQQTLLQDNLLGRVHFDQFKEALILILSRTLSSEEHFQESEAQPKYVKGGKRYGRRSLPEFQESVEEFAEVTVLEPLDEEAKPSHIPSGDCNEHWKTQHSEEYEAKGQLRFWNPDDLNASHSGSCPPQDWIEEKLQEVCEDLGITRDGHLNRKKLVSICEQYGLQNVDGAMLEEVFLSLDPDGTMSVEDFFYGLFKTGKSLAPSASTPYRQLKRHLSMQSFDESGRRTTTSSAMTSTIGFRVFSCLDDGMGQASVERILDAWQEEGIENSQEILKALDFSLDGNVNLTELTLALENELLVTKNGIHQAALASFKAEIRHLLERVDQVVREKEKLRSDLDKAEKLKSLMASEVDDHHAAIERRNECNLRKLDEEYKERIAALKNELRQEREQILQQVSKQRAELEREIEKAKTEENYIRDRLALSLKENHRLENELLENAAKLAEYESLTNKLQHNLENVLAEKFGDLDPSSAEFFLQEERLVQMRNEYEQQCRLLQDQVDELHSELEEYRAQGKVFRLPLKNSLSEELDVNSGGIEPDQGLGSEECNPLNMSIEAELVIEQMKEQHHRDLCHLRLELEEKVYHYEKQLDETRVTCEKEQAAMKQKYEHGMHTLETQISDLRGEIADLQGQAMVLKEAHHEASCRHEEEKKQLQLMFEEEKTQLQEELRLEHERELKARLQQAEENFEQEREELSRSAAWTEEKVRGLTQDLEQSYQEQLLSLVEKHTLEKEELRKELLERHQRELQEGREKMETECNRRASQIEAQFQADCEKVTERCEHTLQSLEGRYRQELKDLLDQHLEERSQWQFEKDELTQECTEAQEQLKEALQREKATALVLNQEREMLEKTYKERLSSLSMERDQLLQDLEDLRNTSESQQGLLSDQILELKRSQERQLRERELCQTGTSEQLASQWLERLQVEREQERGEMVGKLAALESAHRVSCERADLEKAELSAEIRRLQNTVKDMQQAASLSGLQGAHSLVMTGEEAEGNGAMSLLQQGEQLLEENGDVLISLQRAHERAVKENAKMATEISRLQQRLKKLEPGSVMSPCLEEHIIEISGSSREQAESFLSQVKQGESSTTKHILSDLGDCEAQDLGSTGTSSVQRQECKTEELETSLECFSELENSEDTRTESWDLKSQVVQLQEQLTVLRADCDQASERKQDLLFDISVLKKKLKMLERIPETSSRYKLLYEDATRENACLHEELRLMEARYDESLDSNKELTTEVFRLQDEMKKMEEVMETFLSLEKSYDEVKMENEELSALVLRLQGKMEKVLDRAPLHCDSYSLWEAPSEHLEVISDEKLLEFRQTPGCTPKVMSMHHTLEERRQETKWCEQESTRLLARIKAHEIAWFHGTIQTHQEKPSVQNPVLLEESAALLGLQDTHPQHQVTIAELELEKQKLQELTRKLRERVSTLIKQRDAPSQGEKEEELKAMMHDLQITCSEMQRKVELLRYESEKLQEENSILRNEITTLNEEDTISNLKLEELNGSQEELWQKIETVEQEKASIQKMVEKLKKQVSDLKIKNQQLDSENTELSQKNSQNKEELQKLNQRLAEMLCQKKEPGACTSEKWEQENSSLREELDRCKVQTSTLVASLEAELSEVKLQTHIVEQENLLLKDELEKLKQLHRCPDLSDLQQKMASILTYNEQLLKEKEALSEELNSCADKLAKSSVLEHKIATMKQEQTTWEQQSESLKAQLVTSQEKVQDLEDVLQNVNLQMSRIQSDLQVTQQEKEALKQEVMSLRRQLQNAGDKVWISETADHLSGLHGQQKRLSWDKLDHFMDEEPQLLCEESKRLQTVVQNTKADLTHSLEKVRQLESNLLPIKHQKQLHQSCTVKPTEQEKLTLKRECEQSQKEQSPTSRKVSQMSSLERELETIHLENEGLRKKQMQPPRSTVTLSPPSHWDLQLLQQQTCPMVPREQFLQLQQQLLQAEQKNQNLQEELDNRTSETNTPQGSQEHLVNLMEERMIEVEQKLKLVKRLLQEKVNQLKEQLCKNTKTDAMVKNLYVENAQLLKALEMTEQRQKTAEKKNYLLEEKIASLSTIVRNLAPAPLASTPPLRS", "length": 2117, "header": "tr|A0A9J7G3T3-1|A0A9J7G3T3_CRIGR Computationally mapped isoform of Ninein isoform X2 OS=Cricetulus griseus OX=10029 GN=Nin PE=4 SV=1 CANONICAL=A0A9J7G1X1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1X1/entry#A0A9J7JPK8-1", "sequence": { "sequence": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766463", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766463", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "centrosome-templated microtubule nucleation", "id": "GO:0090222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090222", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1X1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1X1" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": 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"ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 43, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1542, "end_pos": 1544 }, { "start_pos": 1630, "end_pos": 1632 }, { "start_pos": 166, "end_pos": 168 }, { "start_pos": 2006, "end_pos": 2008 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 598, "end_pos": 600 }, { "start_pos": 921, "end_pos": 923 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"A0A9J7G260", "uniprot_id": "A0A9J7G260_CRIGR", "mass": { "chemical_mass": 44384.0, "monoisotopic_mass": 44384.0 }, "refseq": { "ac": "XP_027274181", "name": "DNA repair protein RAD51 homolog 2 isoform X11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274181" }, "gene_names": [ { "name": "Rad51b", "type": "recommended", "evidence": [ { "id": "A0A9J7G260", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" } ] }, { "name": "Rad51b", "type": "synonym", "evidence": [ { "id": "XP_027274181", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274181" } ] } ], "protein_names": [ { "name": "DNA repair protein RAD51 homolog 2", "type": "recommended", "evidence": [ { "id": "A0A9J7G260", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#names_and_taxonomy" } ] }, { "name": "DNA repair protein RAD51 homolog 2 isoform X11", "type": "synonym", "evidence": [ { "id": "XP_027274181", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274181" } ] }, { "name": "RAD51 homolog B", "type": "synonym", "evidence": [ { "id": "A0A9J7G260", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#names_and_taxonomy" } ] }, { "name": "RAD51-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7G260", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274181" } ] }, { "annotation": "Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD51 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G209", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G209#function" }, { "database": "UniProtKB", "id": "ARBA00053115", "url": "https://www.uniprot.org/uniprotkb/ARBA00053115#function" }, { "database": "UniProtKB", "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260#function" }, { "database": "UniProtKB", "id": "A0A9J7G2B1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2B1#function" }, { "database": "UniProtKB", "id": "A0A9J7JSQ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSQ8#function" }, { "database": "UniProtKB", "id": "A0A9J7JPQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPQ7#function" }, { "database": "UniProtKB", "id": "A0A9J7H230", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H230#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rad51b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260", "locus": {} } ], "crossref": [ { "id": "cd19493", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19493", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756125", "url": "https://www.ncbi.nlm.nih.gov/gene/100756125", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756125", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756125", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G260", "url": "https://www.orthodb.org/?gene=A0A9J7G260", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JRI2", "url": "https://www.orthodb.org/?gene=A0A9J7JRI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46456", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46456", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46456:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46456:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027274181", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274181", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G1R7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G209", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G209", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G209-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G209-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G260-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2B1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2B1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2B1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H230", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H230", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H230-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H230-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRI2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSQ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNKKLRRVGLSQELCDRLSRHQIVNCQDFLGLSPLELMKVTGLSYGGVQELLYMVSRACAPQMQTAYDIKMRRSAELSPAFLSTTLSALDKALHGGVACGSLTEITGPPGCGKTQFCIMMSVLATLPTNMGGLEGTVVYIDTESAFTAERLVEIAESRFPLYFNTEEKLLLISSKVHLHRELSCEAVLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLAKQASLLKYLAEEFSLPVILTNQITTHLSGALPSQADLVSPADDLSLSEGKGSVLERLKLDTDIQPPAESWETWLLDAGQCSLLEPGTSGSSCVVAALGNSWSHCVNTRLILQYLDSERRQLNTLHCHRPTDSIKPTQPTTCARWRKMFCVHFNSASPFHSGLHPPPL", "length": 403, "header": "tr|A0A9J7G260-1|A0A9J7G260_CRIGR Isoform 1 of DNA repair protein RAD51 homolog 2 OS=Cricetulus griseus OX=10029 GN=Rad51b PE=3 SV=1 CANONICAL=A0A9J7G260-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G1R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#A0A9J7G1R7-1", "sequence": { "sequence": "MSNKKLRRVGLSQELCDRLSRHQIVNCQDFLGLSPLELMKVTGLSYGGVQELLYMVSRACAPQMQTAYDIKMRRSAELSPAFLSTTLSALDKALHGGVACGSLTEITGPPGCGKTQFCIMMSVLATLPTNMGGLEGTVVYIDTESAFTAERLVEIAESRFPLYFNTEEKLLLISSKVHLHRELSCEAVLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLAKQASLLKYLAEEFSLPM", "length": 253, "header": "tr|A0A9J7G1R7-1|A0A9J7G1R7_CRIGR Computationally mapped isoform of DNA repair protein RAD51 homolog 2 isoform X19 OS=Cricetulus griseus OX=10029 GN=Rad51b PE=3 SV=1 CANONICAL=A0A9J7G260-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G209-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#A0A9J7G209-1", "sequence": { "sequence": "MSNKKLRRVGLSQELCDRLSRHQIVNCQDFLGLSPLELMKVTGLSYGGVQELLYMVSRACAPQMQTAYDIKMRRSAELSPAFLSTTLSALDKALHGGVACGSLTEITGPPGCGKTQFCIMMSVLATLPTNMGGLEGTVVYIDTESAFTAERLVEIAESRFPLYFNTEEKLLLISSKVHLHRELSCEAVLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLAKQASLLKYLAEEFSLPVILTNQITTHLSGALPSQADLVSPADDLSLSEGKGSVLERLKLDTDIQPPAESWETWLLDAGQCSLLEPGTSGSSCVVAALGNSWSHCVNTRLILQYLDSERRQILIAKSPLAAFTSFIYTIKGEGLVLQGQERP", "length": 387, "header": "tr|A0A9J7G209-1|A0A9J7G209_CRIGR Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Cricetulus griseus OX=10029 GN=Rad51b PE=3 SV=1 CANONICAL=A0A9J7G260-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G260-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#A0A9J7G260-1", "sequence": { "sequence": "MSNKKLRRVGLSQELCDRLSRHQIVNCQDFLGLSPLELMKVTGLSYGGVQELLYMVSRACAPQMQTAYDIKMRRSAELSPAFLSTTLSALDKALHGGVACGSLTEITGPPGCGKTQFCIMMSVLATLPTNMGGLEGTVVYIDTESAFTAERLVEIAESRFPLYFNTEEKLLLISSKVHLHRELSCEAVLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLAKQASLLKYLAEEFSLPVILTNQITTHLSGALPSQADLVSPADDLSLSEGKGSVLERLKLDTDIQPPAESWETWLLDAGQCSLLEPGTSGSSCVVAALGNSWSHCVNTRLILQYLDSERRQLNTLHCHRPTDSIKPTQPTTCARWRKMFCVHFNSASPFHSGLHPPPL", "length": 403, "header": "tr|A0A9J7G260-1|A0A9J7G260_CRIGR Isoform 1 of DNA repair protein RAD51 homolog 2 OS=Cricetulus griseus OX=10029 GN=Rad51b PE=3 SV=1 CANONICAL=A0A9J7G260-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#A0A9J7G2B1-1", "sequence": { "sequence": "MSNKKLRRVGLSQELCDRLSRHQIVNCQDFLGLSPLELMKVTGLSYGGVQELLYMVSRACAPQMQTAYDIKMRRSAELSPAFLSTTLSALDKALHGGVACGSLTEITGPPGCGKTQFCIMMSVLATLPTNMGGLEGTVVYIDTESAFTAERLVEIAESRFPLYFNTEEKLLLISSKVHLHRELSCEAVLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLAKQASLLKYLAEEFSLPVILTNQITTHLSGALPSQADLVSPADDLSLSEGTSGSSCVVAALGNSWSHCVNTRLILQYLDSERRQLNTLHCHRPTDSIKPTQPTTCARWRKMFCVHFNSASPFHSGLHPPPL", "length": 366, "header": "tr|A0A9J7G2B1-1|A0A9J7G2B1_CRIGR Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Cricetulus griseus OX=10029 GN=Rad51b PE=3 SV=1 CANONICAL=A0A9J7G260-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H230-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#A0A9J7H230-1", "sequence": { "sequence": "MSNKKLRRVGLSQELCDRLSRHQIVNCQDFLGLSPLELMKVTGLSYGGVQELLYMVSRACAPQMQTAYDIKMRRSAELSPAFLSTTLSALDKALHGGVACGSLTEITGPPGCGKTQFCIMMSVLATLPTNMGGLEGTVVYIDTESAFTAERLVEIAESRFPLYFNTEEKLLLISSKVHLHRELSCEAVLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLAKQASLLKYLAEEFSLPVILTNQITTHLSGALPSQADLVSPADDLSLSEGKGSVLERLKLDTDIQPPAESWETWLLDAGQCSLLEPGTSGSSCVVAALGNSWSHCVNTRLILQYLDSERRQVSSWLSVCLLDFGCYPYTLHSLGVVC", "length": 382, "header": "tr|A0A9J7H230-1|A0A9J7H230_CRIGR Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Cricetulus griseus OX=10029 GN=Rad51b PE=3 SV=1 CANONICAL=A0A9J7G260-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#A0A9J7JJM2-1", "sequence": { "sequence": "MSNKKLRRVGLSQELCDRLSRHQIVNCQDFLGLSPLELMKVTGLSYGGVQELLYMVSRACAPQMQTITGPPGCGKTQFCIMMSVLATLPTNMGGLEGTVVYIDTESAFTAERLVEIAESRFPLYFNTEEKLLLISSKVHLHRELSCEAVLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLAKQASLLKYLAEEFSLPVILTNQITTHLSGALPSQADLVSPADDLSLSEGKGSVLERLKLDTDIQPPAESWETWLLDAGQCSLLEPGTSGSSCVVAALGNSWSHCVNTRLILQYLDSERRQLNTLHCHRPTDSIKPTQPTTCARWRKMFCVHFNSASPFHSGLHPPPL", "length": 364, "header": "tr|A0A9J7JJM2-1|A0A9J7JJM2_CRIGR Computationally mapped isoform of DNA repair protein RAD51 homolog 2 isoform X16 OS=Cricetulus griseus OX=10029 GN=Rad51b PE=3 SV=1 CANONICAL=A0A9J7G260-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#A0A9J7JPQ7-1", "sequence": { "sequence": "MSNKKLRRVGLSQELCDRLSRHQIVNCQDFLGLSPLELMKVTGLSYGGVQELLYMVSRACAPQMQTAYDIKMRRSAELSPAFLSTTLSALDKALHGGVACGSLTEITGPPGCGKTQFCIMMSVLATLPTNMGGLEGTVVYIDTESAFTAERLVEIAESRFPLYFNTEEKLLLISSKVHLHRELSCEAVLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLAKQASLLKYLAEEFSLPVILTNQITTHLSGALPSQADLVSPADDLSLSEGKGSVLERLKLDTDIQPPAESWETWLLDAGQCSLLEPGTSGSSCVVAALGNSWSHCVNTRLILQYLDSERRQAKRGHRDPVTFV", "length": 368, "header": "tr|A0A9J7JPQ7-1|A0A9J7JPQ7_CRIGR Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Cricetulus griseus OX=10029 GN=Rad51b PE=3 SV=1 CANONICAL=A0A9J7G260-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#A0A9J7JRI2-1", "sequence": { "sequence": "MSNKKLRRVGLSQELCDRLSRHQIVNCQDFLGLSPLELMKVTGLSYGGVQELLYMVSRACAPQMQTAYDIKMRRSAELSPAFLSTTLSALDKALHGGVACGSLTEITGPPGCGKTQFCIMMSVLATLPTNMGGLEGTVVYIDTESAFTAERLVEIAESRFPLYFNTEEKLLLISSKVHLHRELSCEAVLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLAKQASLLKYLAEEFSLPVPDQI", "length": 257, "header": "tr|A0A9J7JRI2-1|A0A9J7JRI2_CRIGR Computationally mapped isoform of DNA repair protein RAD51 homolog 2 isoform X18 OS=Cricetulus griseus OX=10029 GN=Rad51b PE=3 SV=1 CANONICAL=A0A9J7G260-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260/entry#A0A9J7JSQ8-1", "sequence": { "sequence": "MSNKKLRRVGLSQELCDRLSRHQIVNCQDFLGLSPLELMKVTGLSYGGVQELLYMVSRACAPQMQTAYDIKMRRSAELSPAFLSTTLSALDKALHGGVACGSLTEITGPPGCGKTQFCIMMSVLATLPTNMGGLEGTVVYIDTESAFTAERLVEIAESRFPLYFNTEEKLLLISSKVHLHRELSCEAVLQRLESLEEEIISKGVKLVIVDSIASVVRKEFDPQLQGNIKERNKFLAKQASLLKYLAEEFSLPVILTNQITTHLSGALPSQADLVSPADDLSLSEGTSGSSCVVAALGNSWSHCVNTRLILQYLDSERRQILIAKSPLAAFTSFIYTIKGEGLVLQGQERP", "length": 350, "header": "tr|A0A9J7JSQ8-1|A0A9J7JSQ8_CRIGR Computationally mapped isoform of DNA repair protein RAD51 homolog 2 OS=Cricetulus griseus OX=10029 GN=Rad51b PE=3 SV=1 CANONICAL=A0A9J7G260-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G209", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G209" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G209", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G209" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756125", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756125", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" } ], "pmid": "" }, { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" } ], "pmid": "" }, { "name": "ATP-dependent DNA damage sensor activity", "id": "GO:0140664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140664", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" } ], "pmid": "" }, { "name": "Rad51B-Rad51C-Rad51D-XRCC2 complex", "id": "GO:0033063", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033063", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G260", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G260", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G260" }, { "id": "PS50162", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50162" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RecA family profile 1", "eco_id": "ECO_0000259", "start_pos": 79, "end_pos": 259, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G2C9-1", "uniprot_ac": "A0A9J7G2C9", "uniprot_id": "A0A9J7G2C9_CRIGR", "mass": { "chemical_mass": 257708.0, "monoisotopic_mass": 257708.0 }, "refseq": { "ac": "XP_027274226", "name": "pecanex-like protein 1 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274226" }, "gene_names": [ { "name": "Pcnx1", "type": "recommended", "evidence": [ { "id": "A0A9J7G2C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9" } ] }, { "name": "Pcnx1", "type": "synonym", "evidence": [ { "id": "XP_027274226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274226" } ] } ], "protein_names": [ { "name": "Pecanex-like protein", "type": "recommended", "evidence": [ { "id": "A0A9J7G2C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9/entry#names_and_taxonomy" } ] }, { "name": "pecanex-like protein 1 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_027274226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274226" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274226" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2C9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pcnx1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9", "locus": {} } ], "crossref": [ { "id": "100762643", "url": "https://www.ncbi.nlm.nih.gov/gene/100762643", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762643", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762643", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G2C9", "url": "https://www.orthodb.org/?gene=A0A9J7G2C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12372:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12372:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027274226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274226", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LGX6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LGX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2C9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRJ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMVIVAVYCPVVAAVFIVLKMVNYRLHRALDAGEVVDRRTAEFPDQRAKAKQGNCSARRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGLDPGNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVSLPSHSQHHHVDQSLSSACDTEVASLVPLHSHSYRKEHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDPVSELDSSKPHSGSRESLVEKSCPPAEFQPAGDLRKSNSQPPTKSGKSRALNADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTLSSYKSEQTSSTHIESILSEHEESPKVGKRSARKKCCADSAEERSHGAGDHRTGSDKLALEGSTSGGPPEDPDAQASGEGPDQVAPSSSASEDANKNPHANEFTLPGDRPSEQSAESRAEQSEKPSISTDSRVCKDSGGKQKEGDVRPKSSSVIHRTTSAHKPGRRRTGKKRASSFDSSRHRDYVSFRGVSGSKPHSAVFCHDEDSSDQSDLSRAPSVHSAHQFSSDSSSSATSHSCQSPEGKYSALKTKHGHKDRATDSEHTHRAHPGPEGTAKKRATRRTSSTNSAKTRARVLSLDSGTVACLNDANRLLAPESIKPLTTSKSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPSQVAFPEGEEQDAAPGAAQASEEAVAFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLSLQDGQQGQQSTAQVKVQSRPPSQAAVLSASASLLVRKGSVHLEASHDHASAVGGSSLHDELGKLSSTLYETGGCDMSLVNFEPAARRASNICDTDSHVSSSTSVRFYPHDVLSRPQIRLNRLLTIDTDLLEQQDIDLSPDLAATYGPTEEAAQKVKHYYRFWILPQLWISINFDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNLTTSKFKLYGITFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSIVAVALLYGLCYGALKDSWDGQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLMQSKIFPKTEEKNPEDPLSEVKDPLPEKLSNSVSERLQSDLVVCVVIGVLYFAIHVSTVFTALQPALKYVLYALVGCVGFVTHYVLPQVRKQLPWHCFSRPLLKTAEHNQYEVRNAATMMWFEKLHVWLLVVEKNVIYPLIVLNELSSSAETIASPKKLDTELGALMITVAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVPHSAMLFVQALVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVDPTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRRAKPLDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRHLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDTGGGTSCPGNNAPTVSDPHSNVSQGSTGNPGQAAGSGLHPPTTPYPPTLGTSHSAHSVQSSLVRQSPARASMASQSSYCYSSRHSSLRMSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEATSQSGMACVQHSLPSSSSSSQSIPACKHHTLVGFLGAEGSQSGVTEAQPGSTLSPANSSHARKGEVVYRVQIVDLSQILEGINLSKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPGTRSHIDKAVLLVQIDDKYVTVIETGVLELGAEV", "length": 2341, "header": "tr|A0A9J7G2C9-1|A0A9J7G2C9_CRIGR Isoform 1 of Pecanex-like protein OS=Cricetulus griseus OX=10029 GN=Pcnx1 PE=3 SV=1 CANONICAL=A0A9J7G2C9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LGX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9/entry#A0A8C2LGX6-1", "sequence": { "sequence": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMVIVAVYCPVVAAVFIVLKMVNYRLHRALDAGEVVDRRTAEFPDQRAKAKQGNCSARRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGLDPGNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVSLPSHSQHHHVDQSLSSACDTEVASLVPLHSHSYRKEHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDPVSELDSSKPHSGSRESLVEKSCPPAEFQPAGDLRKSNSQPPTKSGKSRALNADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTLSSYKSEQTSSTHIESILSEHEESPKVGKRSARKKCCADSAEERSHGAGDHRTGSDKLALEGSTSGGPPEDPDAQASGEGPDQVAPSSSASEDANKNPHANEFTLPGDRPSEQSAESRAEQSEKPSISTDSRVCKDSGGKQKEGDVRPKSSSVIHRTTSAHKPGRRRTGKKRASSFDSSRHRDYVSFRGVSGSKPHSAVFCHDEDSSDQSDLSRAPSVHSAHQFSSDSSSSATSHSCQSPEGKYSALKTKHGHKDRATDSEHTHRAHPGPEGTAKKRATRRTSSTNSAKTRARVLSLDSGTVACLNDANRLLAPESIKPLTTSKSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPSQVAFPEGEEQDAAPGAAQASEEAVAFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLSLQDGQQGQQSTAQVKVQSRPPSQAAVLSASASLLVRKGSVHLEASHDHASAVGGSSLHDELGKLSSTLYETGGCDMSLVNFEPAARRASNICDTDSHVSSSTSVRFYPHDVIRLNRLLTIDTDLLEQQDIDLSPDLAATYGPTEEAAQKVKHYYRFWILPQLWISINFDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNLTTSKFKLYGITFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSIVAVALLYGLCYGALKDSWDGQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLMQSKIFPKTEEKNPEDPLSEVKDPLPEKLSNSVSERLQSDLVVCVVIGVLYFAIHVSTVFTALQPALKYVLYALVGCVGFVTHYVLPQVRKQLPWHCFSRPLLKTAEHNQYEVRNAATMMWFEKLHVWLLVVEKNVIYPLIVLNELSSSAETIASPKKLDTELGALMITVAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVPHSAMLFVQALVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVDPTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRRAKPLDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRHLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDTGGGTSCPGNNAPTVSDPHSNVSQGSTGNPGQAAGSGLHPPTTPYPPTLGTSHSAHSVQSSLVRQSPARASMASQSSYCYSSRHSSLRMSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEATSQSGMACVQHSLPSSSSSSQSIPACKHHTLVGFLGAEGSQSGVTEAQPGSTLSPANSSHARKGEVVYRVQIVDLSQILEGINLSKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPGTRSHIDKAVLLVQIDDKYVTVIETGVLELGAEV", "length": 2336, "header": "tr|A0A8C2LGX6-1|A0A8C2LGX6_CRIGR Computationally mapped isoform of Pecanex-like protein OS=Cricetulus griseus OX=10029 GN=Pcnx1 PE=3 SV=1 CANONICAL=A0A9J7G2C9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9/entry#A0A9J7G1T7-1", "sequence": { "sequence": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMVIVAVYCPVVAAVFIVLKMVNYRLHRALDAGEVVDRRTAEFPDQRAKAKQGNCSARRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGLDPGNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVSLPSHSQHHHVDQSLSSACDTEVASLVPLHSHSYRKEHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDPVSELDSSKPHSGSRESLVEKSCPPAEFQPAGDLRKSNSQPPTKSGKSRALNADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTLSSYKSEQTSSTHIESILSEHEESPKVGKRSARKKCCADSAEERSHGAGDHRTGSDKLALEGSTSGGPPEDPDAQASGEGPDQVAPSSSASEDANKNPHANEFTLPGDRPSEQSAESRAEQSEKPSISTDSRVCKDSGGKQKEGDVRPKSSSVIHRTTSAHKPGRRRTGKKRASSFDSSRHRDYVSFRGVSGSKPHSAVFCHDEDSSDQSDLSRAPSVHSAHQFSSDSSSSATSHSCQSPEGKYSALKTKHGHKDRATDSEHTHRAHPGPEGTAKKRATRRTSSTNSAKTRARVLSLDSGTVACLNDANRLLAPESIKPLTTSKSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPSQVAFPEGEEQDAAPGGKLSSTLYETGGCDMSLVNFEPAARRASNICDTDSHVSSSTSVRFYPHDVIRLNRLLTIDTDLLEQQDIDLSPDLAATYGPTEEAAQKVKHYYRFWILPQLWISINFDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNLTTSKFKLYGITFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSIVAVALLYGLCYGALKDSWDGQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLMQSKIFPKTEEKNPEDPLSEVKDPLPEKLSNSVSERLQSDLVVCVVIGVLYFAIHVSTVFTALQPALKYVLYALVGCVGFVTHYVLPQVRKQLPWHCFSRPLLKTAEHNQYEVRNAATMMWFEKLHVWLLVVEKNVIYPLIVLNELSSSAETIASPKKLDTELGALMITVAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVPHSAMLFVQALVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVDPTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRRAKPLDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRHLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDTGGGTSCPGNNAPTVSDPHSNVSQGSTGNPGQAAGSGLHPPTTPYPPTLGTSHSAHSVQSSLVRQSPARASMASQSSYCYSSRHSSLRMSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEATSQSGMACVQHSLPSSSSSSQSIPACKHHTLVGFLGAEGSQSGVTEAQPGSTLSPANSSHARKGEVVYRVQIVDLSQILEGINLSKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPGTRSHIDKAVLLVQIDDKYVTVIETGVLELGAEV", "length": 2230, "header": "tr|A0A9J7G1T7-1|A0A9J7G2C9_CRIGR Computationally mapped isoform of Pecanex-like protein OS=Cricetulus griseus OX=10029 GN=Pcnx1 PE=3 SV=1 CANONICAL=A0A9J7G2C9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9/entry#A0A9J7G2C9-1", "sequence": { "sequence": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMVIVAVYCPVVAAVFIVLKMVNYRLHRALDAGEVVDRRTAEFPDQRAKAKQGNCSARRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGLDPGNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVSLPSHSQHHHVDQSLSSACDTEVASLVPLHSHSYRKEHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDPVSELDSSKPHSGSRESLVEKSCPPAEFQPAGDLRKSNSQPPTKSGKSRALNADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTLSSYKSEQTSSTHIESILSEHEESPKVGKRSARKKCCADSAEERSHGAGDHRTGSDKLALEGSTSGGPPEDPDAQASGEGPDQVAPSSSASEDANKNPHANEFTLPGDRPSEQSAESRAEQSEKPSISTDSRVCKDSGGKQKEGDVRPKSSSVIHRTTSAHKPGRRRTGKKRASSFDSSRHRDYVSFRGVSGSKPHSAVFCHDEDSSDQSDLSRAPSVHSAHQFSSDSSSSATSHSCQSPEGKYSALKTKHGHKDRATDSEHTHRAHPGPEGTAKKRATRRTSSTNSAKTRARVLSLDSGTVACLNDANRLLAPESIKPLTTSKSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPSQVAFPEGEEQDAAPGAAQASEEAVAFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLSLQDGQQGQQSTAQVKVQSRPPSQAAVLSASASLLVRKGSVHLEASHDHASAVGGSSLHDELGKLSSTLYETGGCDMSLVNFEPAARRASNICDTDSHVSSSTSVRFYPHDVLSRPQIRLNRLLTIDTDLLEQQDIDLSPDLAATYGPTEEAAQKVKHYYRFWILPQLWISINFDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNLTTSKFKLYGITFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSIVAVALLYGLCYGALKDSWDGQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLMQSKIFPKTEEKNPEDPLSEVKDPLPEKLSNSVSERLQSDLVVCVVIGVLYFAIHVSTVFTALQPALKYVLYALVGCVGFVTHYVLPQVRKQLPWHCFSRPLLKTAEHNQYEVRNAATMMWFEKLHVWLLVVEKNVIYPLIVLNELSSSAETIASPKKLDTELGALMITVAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVPHSAMLFVQALVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVDPTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRRAKPLDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRHLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDTGGGTSCPGNNAPTVSDPHSNVSQGSTGNPGQAAGSGLHPPTTPYPPTLGTSHSAHSVQSSLVRQSPARASMASQSSYCYSSRHSSLRMSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEATSQSGMACVQHSLPSSSSSSQSIPACKHHTLVGFLGAEGSQSGVTEAQPGSTLSPANSSHARKGEVVYRVQIVDLSQILEGINLSKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPGTRSHIDKAVLLVQIDDKYVTVIETGVLELGAEV", "length": 2341, "header": "tr|A0A9J7G2C9-1|A0A9J7G2C9_CRIGR Isoform 1 of Pecanex-like protein OS=Cricetulus griseus OX=10029 GN=Pcnx1 PE=3 SV=1 CANONICAL=A0A9J7G2C9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H0B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9/entry#A0A9J7H0B0-1", "sequence": { "sequence": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMVIVAVYCPVVAAVFIVLKMVNYRLHRALDAGEVVDRRTAEFPDQRAKAKQGNCSARRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGLDPGNQIGSGSSRLGTAATIKDLATDRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVSLPSHSQHHHVDQSLSSACDTEVASLVPLHSHSYRKEHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDPVSELDSSKPHSGSRESLVEKSCPPAEFQPAGDLRKSNSQPPTKSGKSRALNADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTLSSYKSEQTSSTHIESILSEHEESPKVGKRSARKKCCADSAEERSHGAGDHRTGSDKLALEGSTSGGPPEDPDAQASGEGPDQVAPSSSASEDANKNPHANEFTLPGDRPSEQSAESRAEQSEKPSISTDSRVCKDSGGKQKEGDVRPKSSSVIHRTTSAHKPGRRRTGKKRASSFDSSRHRDYVSFRGVSGSKPHSAVFCHDEDSSDQSDLSRAPSVHSAHQFSSDSSSSATSHSCQSPEGKYSALKTKHGHKDRATDSEHTHRAHPGPEGTAKKRATRRTSSTNSAKTRARVLSLDSGTVACLNDANRLLAPESIKPLTTSKSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPSQVAFPEGEEQDAAPGAAQASEEAVAFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLSLQDGQQGQQSTAQVKVQSRPPSQAAVLSASASLLVRKGSVHLEASHDHASAVGGSSLHDELGKLSSTLYETGGCDMSLVNFEPAARRASNICDTDSHVSSSTSVRFYPHDVLSRPQIRLNRLLTIDTDLLEQQDIDLSPDLAATYGPTEEAAQKVKHYYRFWILPQLWISINFDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNLTTSKFKLYGITFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSIVAVALLYGLCYGALKDSWDGQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLMQSKIFPKTEEKNPEDPLSEVKDPLPEKLSNSVSERLQSDLVVCVVIGVLYFAIHVSTVFTALQPALKYVLYALVGCVGFVTHYVLPQVRKQLPWHCFSRPLLKTAEHNQYEVRNAATMMWFEKLHVWLLVVEKNVIYPLIVLNELSSSAETIASPKKLDTELGALMITVAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVPHSAMLFVQALVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVDPTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRRAKPLDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRHLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDTGGGTSCPGNNAPTVSDPHSNVSQGSTGNPGQAAGSGLHPPTTPYPPTLGTSHSAHSVQSSLVRQSPARASMASQSSYCYSSRHSSLRMSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEATSQSGMACVQHSLPSSSSSSQSIPACKHHTLVGFLGAEGSQSGVTEAQPGSTLSPANSSHARKGEVVYRVQIVDLSQILEGINLSKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPGTRSHIDKAVLLVQIDDKYVTVIETGVLELGAEV", "length": 2311, "header": "tr|A0A9J7H0B0-1|A0A9J7H0B0_CRIGR Computationally mapped isoform of Pecanex-like protein OS=Cricetulus griseus OX=10029 GN=Pcnx1 PE=3 SV=1 CANONICAL=A0A9J7G2C9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9/entry#A0A9J7JJN2-1", "sequence": { "sequence": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMVIVAVYCPVVAAVFIVLKMVNYRLHRALDAGEVVDRRTAEFPDQRAKAKQGNCSARRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGLDPGNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVSLPSHSQHHHVDQSLSSACDTEVASLVPLHSHSYRKEHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDPVSELDSSKPHSGSRESLVEKSCPPAEFQPAGDLRKSNSQPPTKSGKSRALNADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTLSSYKSEQTSSTHIESILSEHEESPKVGKRSARKKCCADSAEERSHGAGDHRTGSDKLALEGSTSGGPPEDPDAQASGEGPDQVAPSSSASEDANKNPHANEFTLPGDRPSEQSAESRAEQSEKPSISTDSRVCKDSGGKQKEGDVRPKSSSVIHRTTSAHKPGRRRTGKKRASSFDSSRHRDYVSFRGVSGSKPHSAVFCHDEDSSDQSDLSRAPSVHSAHQFSSDSSSSATSHSCQSPEGKYSALKTKHGHKDRATDSEHTHRAHPGPEGTAKKRATRRTSSTNSAKTRARVLSLDSGTVACLNDANRLLAPESIKPLTTSKSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPSQVAFPEGEEQDAAPGAQASEEAVAFRRERSTFRRQAVRRRHNAGSNPTPPTLLIGSPLSLQDGQQGQQSTAQVKVQSRPPSQAAVLSASASLLVRKGSVHLEASHDHASAVGGSSLHDELGKLSSTLYETGGCDMSLVNFEPAARRASNICDTDSHVSSSTSVRFYPHDVLSRPQIRLNRLLTIDTDLLEQQDIDLSPDLAATYGPTEEAAQKVKHYYRFWILPQLWISINFDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNLTTSKFKLYGITFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSIVAVALLYGLCYGALKDSWDGQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLMQSKIFPKTEEKNPEDPLSEVKDPLPEKLSNSVSERLQSDLVVCVVIGVLYFAIHVSTVFTALQPALKYVLYALVGCVGFVTHYVLPQVRKQLPWHCFSRPLLKTAEHNQYEVRNAATMMWFEKLHVWLLVVEKNVIYPLIVLNELSSSAETIASPKKLDTELGALMITVAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVPHSAMLFVQALVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVDPTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRRAKPLDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRHLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDTGGGTSCPGNNAPTVSDPHSNVSQGSTGNPGQAAGSGLHPPTTPYPPTLGTSHSAHSVQSSLVRQSPARASMASQSSYCYSSRHSSLRMSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEATSQSGMACVQHSLPSSSSSSQSIPACKHHTLVGFLGAEGSQSGVTEAQPGSTLSPANSSHARKGEVVYRVQIVDLSQILEGINLSKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPGTRSHIDKAVLLVQIDDKYVTVIETGVLELGAEV", "length": 2340, "header": "tr|A0A9J7JJN2-1|A0A9J7JJN2_CRIGR Computationally mapped isoform of Pecanex-like protein OS=Cricetulus griseus OX=10029 GN=Pcnx1 PE=3 SV=1 CANONICAL=A0A9J7G2C9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9/entry#A0A9J7JRJ3-1", "sequence": { "sequence": "MGSQTLQILRQGVWAALSGGWYYDPHQATFVNALHLYLWLFLLGLPFTLYMALPSSMVIVAVYCPVVAAVFIVLKMVNYRLHRALDAGEVVDRRTAEFPDQRAKAKQGNCSARRKDSNGPSDPGGGIEMSEFIREATPPVGCSSRNSYAGLDPGNQIGSGSSRLGTAATIKGDTDTAKTSDDISLSLGQSSSLCKEGSEEQDLATDRKLFRLVSNDSFISIQPSLSSCGQDLPRDFSDKVSLPSHSQHHHVDQSLSSACDTEVASLVPLHSHSYRKEHRPRGVPRTSSSAVAFPDASLNDFPLYQQRRGLDPVSELDSSKPHSGSRESLVEKSCPPAEFQPAGDLRKSNSQPPTKSGKSRALNADKSVDSLRSLSTRSSGSTESYCSGTDRDTNSTLSSYKSEQTSSTHIESILSEHEESPKVGKRSARKKCCADSAEERSHGAGDHRTGSDKLALEGSTSGGPPEDPDAQASGEGPDQVAPSSSASEDANKNPHANEFTLPGDRPSEQSAESRAEQSEKPSISTDSRVCKDSGGKQKEGDVRPKSSSVIHRTTSAHKPGRRRTGKKRASSFDSSRHRDYVSFRGVSGSKPHSAVFCHDEDSSDQSDLSRAPSVHSAHQFSSDSSSSATSHSCQSPEGKYSALKTKHGHKDRATDSEHTHRAHPGPEGTAKKRATRRTSSTNSAKTRARVLSLDSGTVACLNDANRLLAPESIKPLTTSKSDLEAKEGEVLDELSLLGRASQLETVTRSRNSLPSQVAFPEGEEQDAAPGGKLSSTLYETGGCDMSLVNFEPAARRASNICDTDSHVSSSTSVRFYPHDVLSRPQIRLNRLLTIDTDLLEQQDIDLSPDLAATYGPTEEAAQKVKHYYRFWILPQLWISINFDRLTLLALFDRNREILENILAVVLAILVAFLGSILLIQGFFRDIWVFQFCLVIASCQYSLLKSVQPDSSSPRHGHNRIIAYSRPVYFCLCCGLIWLLDYGSRNLTTSKFKLYGITFTNPLVLLSARDLVIVFTLCFPIVFFIGLLPQVNTFVMYLCEQLDIHIFGGNATTSLLAALYSFLCSIVAVALLYGLCYGALKDSWDGQHIPVLFSVFCGLLVAVSYHLSRQSSDPSVLFSLMQSKIFPKTEEKNPEDPLSEVKDPLPEKLSNSVSERLQSDLVVCVVIGVLYFAIHVSTVFTALQPALKYVLYALVGCVGFVTHYVLPQVRKQLPWHCFSRPLLKTAEHNQYEVRNAATMMWFEKLHVWLLVVEKNVIYPLIVLNELSSSAETIASPKKLDTELGALMITVAGLKLLRSSFSSPTYQYITVIFTVLFFKFDYEAFSETMLLDLFFMSILFSKLWELLYKLQFVYTYVAPWQITWGSAFHAFAQPFAVPHSAMLFVQALVSAFFSTPLNPFLGSAIFITSYVRPVKFWERDYNTKRVDHSNTRLASQLDRNPGSDDNNLNSIFYEHLTRSLQHSLCGDLLLGRWGNYSTGDCFILASDYLNALVHLIEIGNGLVTFQLRGLEFRGTYCQQREVEAITEGVEEDEGFCCCEPGHVPHVLSFNAAFGQRWLAWEVVVTKYILEGYSITDNSAASMLQVFDLRRVLTTYYVKGIIYYVTTSSKLEEWLANETMQEGLRLCADRNYVDVDPTFNPNIDEDYDHRLAGISRESFCVIYLNWIEYCSSRRAKPLDVDKDSSLVTLCYGLCVLGRRALGTASHHMSSNLESFLYGLHALFKGDFRISSVRDEWIFADMELLRKVVVPGIRMSIKLHQDHFTSPDEYDDPTVLYEAIVSHEKNLVIAHEGDPAWRSAVLANSPSLLALRHVMDDGTNEYKIIMLNRRHLSFRVIKVNKECVRGLWAGQQQELVFLRNRNPERGSIQNAKQALRNMINSSCDQPIGYPIFVSPLTTSYSDSHDQLKEILGGPISLGNIRNFIVSTWHRLRKGCGAGCNSGGNIEDSDTGGGTSCPGNNAPTVSDPHSNVSQGSTGNPGQAAGSGLHPPTTPYPPTLGTSHSAHSVQSSLVRQSPARASMASQSSYCYSSRHSSLRMSTTGFVPCRRSSTSQISLRNLPSSIQSRLSMVNQMEATSQSGMACVQHSLPSSSSSSQSIPACKHHTLVGFLGAEGSQSGVTEAQPGSTLSPANSSHARKGEVVYRVQIVDLSQILEGINLSKRKELQWPDEGIRLKAGRNSWKDWSPQEGMEGHVIHRWVPCSRDPGTRSHIDKAVLLVQIDDKYVTVIETGVLELGAEV", "length": 2235, "header": "tr|A0A9J7JRJ3-1|A0A9J7JRJ3_CRIGR Computationally mapped isoform of Pecanex-like protein OS=Cricetulus griseus OX=10029 GN=Pcnx1 PE=3 SV=1 CANONICAL=A0A9J7G2C9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 804, "start_aa": "Thr", "end_pos": 804, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr804", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1T7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1T7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762643", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762643", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2C9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1091, "end_pos": 1093, "annotation": "n_glycosylation_sequon" }, { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1155, "end_pos": 1157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1579, "end_pos": 1581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1720, "end_pos": 1722, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1982, "end_pos": 1984, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2072, "end_pos": 2074, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2234, "end_pos": 2236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2260, "end_pos": 2262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G2C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2C9" }, { "id": "PF05041", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pecanex C-terminal", "eco_id": "ECO_0000259", "start_pos": 1782, "end_pos": 2008, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 804 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1091, "end_pos": 1093 }, { "start_pos": 109, "end_pos": 111 }, { "start_pos": 1155, "end_pos": 1157 }, { "start_pos": 1579, "end_pos": 1581 }, { "start_pos": 1720, "end_pos": 1722 }, { "start_pos": 1982, "end_pos": 1984 }, { "start_pos": 2072, "end_pos": 2074 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 2234, "end_pos": 2236 }, { "start_pos": 2260, "end_pos": 2262 }, { "start_pos": 394, "end_pos": 396 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G1U2-1", "uniprot_ac": "A0A9J7G1U2", "uniprot_id": "A0A9J7G1U2_CRIGR", "mass": { "chemical_mass": 40547.0, "monoisotopic_mass": 40547.0 }, "refseq": { "ac": "XP_007630815", "name": "REST corepressor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007630815" }, "gene_names": [ { "name": "Rcor1", "type": "recommended", "evidence": [ { "id": "A0A9J7G1U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1U2" } ] }, { "name": "Rcor1", "type": "synonym", "evidence": [ { "id": "XP_007630815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007630815" } ] } ], "protein_names": [ { "name": "REST corepressor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007630815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007630815" }, { "id": "A0A9J7G1U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1U2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613702.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007630815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007630815" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1U2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rcor1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1U2", "locus": {} } ], "crossref": [ { "id": "A0A9J7G1U2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G1U2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773394", "url": "https://www.ncbi.nlm.nih.gov/gene/100773394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051066", "database": "InterPro", "categories": [ 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274027", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274027" } ] }, { "annotation": "Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1Z0#function" }, { "database": "UniProtKB", "id": "ARBA00037306", "url": "https://www.uniprot.org/uniprotkb/ARBA00037306#function" }, { "database": "UniProtKB", "id": "A0A8C2MF06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF06#function" }, { "database": "UniProtKB", "id": "A0A9J7GZR9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZR9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": 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Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271852" } ] }, { "annotation": "RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G273", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273#function" }, { "database": "UniProtKB", "id": "ARBA00058359", "url": "https://www.uniprot.org/uniprotkb/ARBA00058359#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G273", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Msi1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273", "locus": {} } ], "crossref": [ { "id": "A0A9J7G273", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G273", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12323", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12323", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12576", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12576", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764296", "url": "https://www.ncbi.nlm.nih.gov/gene/100764296", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764296", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764296", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G273", "url": "https://www.orthodb.org/?gene=A0A9J7G273", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48032", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48032", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48032:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48032:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271852", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G273", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G273-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GTN3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GTN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METDAPQPGLASPDSPHDPGTMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 351, "header": "tr|A0A9J7G273-1|A0A9J7G273_CRIGR Isoform 1 of RNA-binding protein Musashi homolog 1 OS=Cricetulus griseus OX=10029 GN=Msi1 PE=3 SV=1 CANONICAL=A0A9J7G273-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G273-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273/entry#A0A9J7G273-1", "sequence": { "sequence": "METDAPQPGLASPDSPHDPGTMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 351, "header": "tr|A0A9J7G273-1|A0A9J7G273_CRIGR Isoform 1 of RNA-binding protein Musashi homolog 1 OS=Cricetulus griseus OX=10029 GN=Msi1 PE=3 SV=1 CANONICAL=A0A9J7G273-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GTN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273/entry#A0A9J7GTN3-1", "sequence": { "sequence": "MVTRTKKIFVGGLSVNTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERTPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSHPWTMAPPPGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH", "length": 259, "header": "tr|A0A9J7GTN3-1|A0A9J7GTN3_CRIGR Computationally mapped isoform of RNA-binding protein Musashi homolog 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Msi1 PE=3 SV=1 CANONICAL=A0A9J7G273-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 289, "start_aa": "Thr", "end_pos": 289, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr289", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G273", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G273", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764296", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764296", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G273", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G273", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G273", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G273", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273" } ], "pmid": "" }, { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G273", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G273", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G273" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 110, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 289 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G279-1", "uniprot_ac": "A0A9J7G279", "uniprot_id": "A0A9J7G279_CRIGR", "mass": { "chemical_mass": 31278.0, "monoisotopic_mass": 31278.0 }, "refseq": { "ac": "XP_003495023", "name": "RRP15-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495023" }, "gene_names": [ { "name": "Rrp15", "type": "recommended", "evidence": [ { "id": "A0A9J7G279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279" } ] }, { "name": "Rrp15", "type": "synonym", "evidence": [ { "id": "XP_003495023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495023" } ] } ], "protein_names": [ { "name": "RRP15-like protein", "type": "recommended", "evidence": [ { "id": "A0A9J7G279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279/entry#names_and_taxonomy" } ] }, { "name": "RRP15-like protein", "type": "synonym", "evidence": [ { "id": "XP_003495023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495023" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613581.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495023" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G279", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rrp15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279", "locus": {} } ], "crossref": [ { "id": "A0A9J7G279", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G279", "database": "AlphaFoldDB", "categories": [] }, { "id": "100750619", "url": "https://www.ncbi.nlm.nih.gov/gene/100750619", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750619", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750619", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G279", "url": "https://www.orthodb.org/?gene=A0A9J7G279", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13245:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13245:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07890", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07890", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G279", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G279-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATVQDSRVRAGKKLKRSLKRKKKMKLVAKAEMSNPEDELKHSSDGEGSEGSGESEMDQLSEDGAVEADSEDNVDSCEEEKEDAEPSAGTNSGWADAMAKILNKKTPSSKPTILTKNKELEKEKEKLKQERLEKRKQLDKKREWEMMCRVKPDVVKDKEAERNLQRIATRGVVQLFNAVQKHQRNVGEKVKEAGGSIRKRAKLMSTVSKKDFISVLRGMDSTNENSSAATNPKARQTEMKSEEGPGWKILQDDFMMGASMKDWDKESDEPGGGRAGSASD", "length": 281, "header": "tr|A0A9J7G279-1|A0A9J7G279_CRIGR Isoform 1 of RRP15-like protein OS=Cricetulus griseus OX=10029 GN=Rrp15 PE=3 SV=1 CANONICAL=A0A9J7G279-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G279-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279/entry#A0A9J7G279-1", "sequence": { "sequence": "MAATVQDSRVRAGKKLKRSLKRKKKMKLVAKAEMSNPEDELKHSSDGEGSEGSGESEMDQLSEDGAVEADSEDNVDSCEEEKEDAEPSAGTNSGWADAMAKILNKKTPSSKPTILTKNKELEKEKEKLKQERLEKRKQLDKKREWEMMCRVKPDVVKDKEAERNLQRIATRGVVQLFNAVQKHQRNVGEKVKEAGGSIRKRAKLMSTVSKKDFISVLRGMDSTNENSSAATNPKARQTEMKSEEGPGWKILQDDFMMGASMKDWDKESDEPGGGRAGSASD", "length": 281, "header": "tr|A0A9J7G279-1|A0A9J7G279_CRIGR Isoform 1 of RRP15-like protein OS=Cricetulus griseus OX=10029 GN=Rrp15 PE=3 SV=1 CANONICAL=A0A9J7G279-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G279", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G279", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750619", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750619", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "preribosome, large subunit precursor", "id": "GO:0030687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030687", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G279", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "maturation of 5.8S rRNA", "id": "GO:0000460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000460", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G279", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279" } ], "pmid": "" }, { "name": "maturation of LSU-rRNA", "id": "GO:0000470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000470", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G279", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G279" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G3A6-1", "uniprot_ac": "A0A9J7G3A6", "uniprot_id": "A0A9J7G3A6_CRIGR", "mass": { "chemical_mass": 51996.0, "monoisotopic_mass": 51996.0 }, "refseq": { "ac": "XP_027275082", "name": "cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275082" }, "gene_names": [ { "name": "Creb3l3", "type": "recommended", "evidence": [ { "id": "A0A9J7G3A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A6" } ] }, { "name": "Creb3l3", "type": "synonym", "evidence": [ { "id": "XP_027275082", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275082" } ] } ], "protein_names": [ { "name": "Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7G3A6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A6/entry#names_and_taxonomy" } ] }, { "name": "cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027275082", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275082" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275082" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3A6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Creb3l3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A6", "locus": {} } ], "crossref": [ { "id": "A0A9J7G3A6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G3A6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14689", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14689", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774488", "url": "https://www.ncbi.nlm.nih.gov/gene/100774488", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774488", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774488", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G3A6", "url": "https://www.orthodb.org/?gene=A0A9J7G3A6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45996", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45996", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45996:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45996:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275082", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G280", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G280", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G280-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G280-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3A6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6J4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYN4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGDIATGKMASPACTMGPLNSLELLDLLFDRQDGILRNVELAEGWGHAGKEQVLPNSDSDDFLNSILGPGDSDPSSPIWSPADSDSGFSEDLPSDPQDTPPHSSPGAANTTARCHPSQQDKGPCPPYLSSAPCPAPPRTQVLESSVAIDLDLWSTDMLYPEEQAGSPSRFNLTVKELLLSGSGGDLQQHSLASSQLLGPGSGHCQELVLTEDEKKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLRHLQALVVQSSSKSAHAGTCIAVLLLSFVLIVLPSISPFDSNKVDSPGDFVPVRVFSRTLHNHAASRVAPDITPGSEVPGPWPDVGTPHKGSPSSSLGADWGNFIEIPMLSDSTEELDNSTLVLVNTTEDLGRATLLDWVALESLLSPGRVGLEMPGMEMWLSWVPRWLRVRLVRGALEVL", "length": 479, "header": "tr|A0A9J7G3A6-1|A0A9J7G3A6_CRIGR Isoform 1 of Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Creb3l3 PE=3 SV=1 CANONICAL=A0A9J7G3A6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G280-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A6/entry#A0A9J7G280-1", "sequence": { "sequence": "MDGDIATGKMASPACTMGPLNSLELLDLLFDRQDGILRNVELAEGWGHAGKEQVLPNSDSDDFLNSILGPGDSDPSSPIWSPADSDSGFSEDLPSDPQDTPPHSSPGAANTTARCHPSQQDKGPCPPYLSSAPCPAPPRTQVLESSVAIDLDLWSTDMLYPEEQAGSPSRFNLTVKELLLSGSGGDLYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLRHLQALVVQSSSKSAHAGTCIAVLLLSFVLIVLPSISPFDSNKVDSPGDFVPVRVFSRTLHNHAASRVAPDITPGSEVPGPWPDVGTPHKGSPSSSLGADWGNFIEIPMLSDSTEELDNSTLVLVNTTEDLGRATLLDWVALESLLSPGRVGLEMPGMEMWLSWVPRWLRVRLVRGALEVL", "length": 433, "header": "tr|A0A9J7G280-1|A0A9J7G3A6_CRIGR Computationally mapped isoform of Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Creb3l3 PE=3 SV=1 CANONICAL=A0A9J7G3A6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A6/entry#A0A9J7G3A6-1", "sequence": { "sequence": "MDGDIATGKMASPACTMGPLNSLELLDLLFDRQDGILRNVELAEGWGHAGKEQVLPNSDSDDFLNSILGPGDSDPSSPIWSPADSDSGFSEDLPSDPQDTPPHSSPGAANTTARCHPSQQDKGPCPPYLSSAPCPAPPRTQVLESSVAIDLDLWSTDMLYPEEQAGSPSRFNLTVKELLLSGSGGDLQQHSLASSQLLGPGSGHCQELVLTEDEKKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLRHLQALVVQSSSKSAHAGTCIAVLLLSFVLIVLPSISPFDSNKVDSPGDFVPVRVFSRTLHNHAASRVAPDITPGSEVPGPWPDVGTPHKGSPSSSLGADWGNFIEIPMLSDSTEELDNSTLVLVNTTEDLGRATLLDWVALESLLSPGRVGLEMPGMEMWLSWVPRWLRVRLVRGALEVL", "length": 479, "header": "tr|A0A9J7G3A6-1|A0A9J7G3A6_CRIGR Isoform 1 of Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Creb3l3 PE=3 SV=1 CANONICAL=A0A9J7G3A6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A6/entry#A0A9J7G6J4-1", "sequence": { "sequence": "MDGDIATGKMASPACTMGPLNSLELLDLLFDRQDGILRNVELAEGWGHAGKEQVLPNSDSDDFLNSILGPGDSDPSSPIWSPADSDSGFSEDLPSDPQDTPPHSSPGAANTTARCHPSQQDKGPCPPYLSSAPCPAPPRTQVLESSVAIDLDLWSTDMLYPEEQAGSPSRFNLTVKELLLSGSGGDLQQHSLASSQLLGPGSGHCQELVLTEDEKKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLRHLQALVVQSSSKSAHAGTCIAPFRLQQGRQPWRLRASASVFQNPPQSRCIPRGSRHHPRLRGPRTLARRWHTPQRFSFQQPRCRLGEFYRNTNAE", "length": 394, "header": "tr|A0A9J7G6J4-1|A0A9J7G6J4_CRIGR Computationally mapped isoform of Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Creb3l3 PE=3 SV=1 CANONICAL=A0A9J7G3A6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A6/entry#A0A9J7JYN4-1", "sequence": { "sequence": "MASPACTMGPLNSLELLDLLFDRQDGILRNVELAEGWGHAGKEQVLPNSDSDDFLNSILGPGDSDPSSPIWSPADSDSGFSEDLPSDPQDTPPHSSPGAANTTARCHPSQQDKGPCPPYLSSAPCPAPPRTQVLESSVAIDLDLWSTDMLYPEEQAGSPSRFNLTVKELLLSGSGGDLQQHSLASSQLLGPGSGHCQELVLTEDEKKLLAKEGVTLPTQLPLTKYEERVLKKIRRKIRNKQSAQESRKKKKEYIDGLENRMSACTAQNQELQRKVLHLEKQNLSLLEQLRHLQALVVQSSSKSAHAGTCIAVLLLSFVLIVLPSISPFDSNKVDSPGDFVPVRVFSRTLHNHAASRVAPDITPGSEVPGPWPDVGTPHKGSPSSSLGADWGNFIEIPMLSDSTEELDNSTLVLVNTTEDLGRATLLDWVALESLLSPGRVGLEMPGMEMWLSWVPRWLRVRLVRGALEVL", "length": 470, "header": "tr|A0A9J7JYN4-1|A0A9J7JYN4_CRIGR Computationally mapped isoform of Cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Creb3l3 PE=3 SV=1 CANONICAL=A0A9J7G3A6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003613669.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274174" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G286", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G286" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rdh11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G286", "locus": {} } ], "crossref": [ { "id": "A0A9J7G286", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G286", "database": "AlphaFoldDB", "categories": [] }, { "id": "100759877", "url": "https://www.ncbi.nlm.nih.gov/gene/100759877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759877", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759877", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G286", "url": "https://www.orthodb.org/?gene=A0A9J7G286", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43157:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43157:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027274174", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274174", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25033", "url": "https://www.rhea-db.org/rhea/25033", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G286", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G286", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G286-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G286-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVAILLLLCLPFIFCLATPRIRKMLSCGMCTSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVQKGELVASEIQATTGNNQVLVRKLDLADTKSIRAFAKDFLAEEKHLHILINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLGKLRDSAPSRVVNVSSLAHHLGRIHFHNLQGEKFYSAGLAYCHSKLANILFTQELARRLKGSGVTTYSVHPGTVHSDLIRHSSFMKWLWQLFFLFIKTPQQGAQTSLYCALTEGLETLSGSHFSDCHLAWVSSQGRNETVARRLWDVSCDLLGLPLDW", "length": 316, "header": "tr|A0A9J7G286-1|A0A9J7G286_CRIGR Isoform 1 of NADP-retinol dehydrogenase OS=Cricetulus griseus OX=10029 GN=Rdh11 PE=3 SV=1 CANONICAL=A0A9J7G286-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G286-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G286/entry#A0A9J7G286-1", "sequence": { "sequence": "MVAILLLLCLPFIFCLATPRIRKMLSCGMCTSNVQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVQKGELVASEIQATTGNNQVLVRKLDLADTKSIRAFAKDFLAEEKHLHILINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTHLLLGKLRDSAPSRVVNVSSLAHHLGRIHFHNLQGEKFYSAGLAYCHSKLANILFTQELARRLKGSGVTTYSVHPGTVHSDLIRHSSFMKWLWQLFFLFIKTPQQGAQTSLYCALTEGLETLSGSHFSDCHLAWVSSQGRNETVARRLWDVSCDLLGLPLDW", "length": 316, "header": "tr|A0A9J7G286-1|A0A9J7G286_CRIGR Isoform 1 of NADP-retinol dehydrogenase OS=Cricetulus griseus OX=10029 GN=Rdh11 PE=3 SV=1 CANONICAL=A0A9J7G286-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G286", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G286" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759877", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759877", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "all-trans-retinol dehydrogenase (NADP+) activity", "id": "GO:0052650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052650", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G286", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G286" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { 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This record is derived from a genomic sequence (NW_003613777.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007639077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639077" } ] }, { "annotation": "Microtubule-dependent motor protein required for mitochondrion morphology and transport of mitochondria in neuronal cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2E5#function" }, { "database": "UniProtKB", "id": "ARBA00054688", "url": "https://www.uniprot.org/uniprotkb/ARBA00054688#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2E5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": 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"length": 1027, "header": "tr|A0A9J7G2E5-1|A0A9J7G2E5_CRIGR Isoform 1 of Kinesin-like protein KIF28 OS=Cricetulus griseus OX=10029 GN=LOC103161207 PE=3 SV=1 CANONICAL=A0A9J7G2E5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2E5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103161207", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103161207", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2E5" } ], "pmid": "" }, { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2E5" } ], "pmid": "" }, { "name": "microtubule motor activity", "id": "GO:0003777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003777", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2E5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2E5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "organelle transport along microtubule", "id": "GO:0072384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072384", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2E5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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} ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275219" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Abca7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2", "locus": {} } ], "crossref": [ { "id": "cd03263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764464", "url": "https://www.ncbi.nlm.nih.gov/gene/100764464", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764464", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764464", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G2F2", "url": "https://www.orthodb.org/?gene=A0A9J7G2F2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G3K1", "url": "https://www.orthodb.org/?gene=A0A9J7G3K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G5I4", "url": "https://www.orthodb.org/?gene=A0A9J7G5I4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G6R6", "url": "https://www.orthodb.org/?gene=A0A9J7G6R6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G7Y4", "url": "https://www.orthodb.org/?gene=A0A9J7G7Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JTU7", "url": "https://www.orthodb.org/?gene=A0A9J7JTU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275219", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3K1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3K1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5I4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5I4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6R6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6R6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7Y4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNEDQRQSGIYLEPHSSLSTYCFCCPLCCFPSRVIMAFCTQLMLLLWKNYTYRKRQPIQLLVELLWPLFLFFILVSVRHSHPPLEHHECHFTNKPLPSAGTVPWLQGLICNVNNSCFQQPTPGEKPGVLSNFKDSLISRLLADTRTVLGGRSTTEMLAALGKLMPLLRGLGGGVWPQDSNLQNKQASVTTELKKILQGVRRSWHGEVSLDPVLGQAQGPLRKFLDATGDLTQELLNLPSLLELRALLHRPRGSAGSLELISEVLCSTKGPSSPGGLSLNWYDTSQLNEFMDPELAPALPDSSLSPACSKFVGSLNDHPVSLLLWSRLKPLILGKILFTPDTNFTRKLMAQVNRTFEELALLRDLQEVWEVLGPQIFNFMNDSSNMAMLQRLLAVEDLGWRHQTPRGQQKLEAVRDFLDPSRGGYNWQKAHADIGHLAEILGQIMECVSLDKLEAVPSEAALVSRALELLGERRLWAGVVFLSTKDPVDRSELSSPALGPGHLRFKIRMDIDVVTSTDKIRDKFWDPGPSADPFMDLRYVWGGFVYLQDLLEQAAVRVLSGRDSHTGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLSWIYSVALTVKAVVHEKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGDILPYSHPAVLFFFLAAFAVATVAQSFLLSAFFSRANLAAACGGLIYFSLYLPYVLCVAWRERLPKGIRVAASLLSPVAFGFGCESLALLEEQGDGAQWHNLGSDPAEDIFSLAQVSAFLLVDAAIYGLALWYLEAVCPGQYGIPEPWDFPFRRSYWYGPGPPQGSDLAPAPQDPKVLVEEPLPGLIPGVSIRGLKKHFHGCPQPALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSASILGHDVQTNMAAIRPHLGICPQYNVLFDLLTVEEHVWFYGRLKGLSAAAMIPEQEHLIQDVGLILKRDTQTRHLSGGMQRKLSVAIAFVGGSRVVILDEPTAGVDPASRRGIWELLLKYREGRTLILSTHYLDEAELLGDRVAVVASGSLCCCGSPLFLRRRLGSGYYLTLVKSPQSRNIQGSKGNSGKSRQEQKPDSEGSMAGTTLTQETLDGSSQAPTPDAAPITPRTPKILDLVKRHVPEAQLVEELPHELVLALPYTGALDGSFGMVFQELDQQLEALGLTGYGISDTNLEEIFLKVVEDAQREGGDSGQYLHPRTATQQPHTGPEVSALENGELARLMLDPQGLQVFTPNAAPVQGWTLTCQQLRALLHKRFLLAHRSHWGLFAQIVLPALFVGLALLFSLIVPPFSQYPPLQLSPAMYGPQVSFFSEDAPQDPNQVKLLEALLEEAGLHNPSMQGVAARGPKCTHSLDCYFSVPEVPADVAHILALGNWTPESPSPACLCSQPGARRLLPDCPAGAGGPPPPQAIAGLGEVVQNLTGRNVSDFLVKTYSSLVRRGLKTKKWVDEVRYGGFSLGGGDPDLPSGYEVIHTVSEMRALLSPQPGKALDRILNNLTQWALGLDARNNLKIWFNNKGWHAMVAFVNRANNGLLHALLPTGTSHHAHGITTFNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLVSGLPQTLYWLGNFFWDMCNYLVAMCIVVFIFLAFQQRAYVSPQNLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELLSDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMEDAFERLGDKQFQSPLRWDVIGKNLLAMVVQGPLFLLITLILQHRNHLLPQSKPKLLPPLGEEDEDVAQERGRVTKGATTGDVLVLRDLTKVYRGQRSPAVDRLCLGIAPGECFGLLGVNGAGKTSTFRMVTGDTLPSSGEAVLAGHNVAQEPAAAHRSMGYCPQSDAIFDLLTGREHLELFARLRGLPKAQAAQTALSGLVRLGLSSYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLSVVHEGRSVVLTSHSMEECEALCTRLAIMVNGRFRCLGSPQHLKGRFGTGHTLTLMVPPEQPEPTIAFVMATFPGAVLREMHGSRLRFQLPPGGSCTLARVFQELAAQGKDHGVEDFSVSQTTLEEVFLHFSKDQGEEEDNWQETGAWELSTPGLQHPKRVSRFLEDPSSMETVL", "length": 2210, "header": "tr|A0A9J7G2F2-1|A0A9J7G2F2_CRIGR Isoform 1 of Phospholipid-transporting ATPase ABCA7 isoform X1 OS=Cricetulus griseus OX=10029 GN=Abca7 PE=4 SV=1 CANONICAL=A0A9J7G2F2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G2F2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2/entry#A0A9J7G2F2-1", "sequence": { "sequence": "MKNEDQRQSGIYLEPHSSLSTYCFCCPLCCFPSRVIMAFCTQLMLLLWKNYTYRKRQPIQLLVELLWPLFLFFILVSVRHSHPPLEHHECHFTNKPLPSAGTVPWLQGLICNVNNSCFQQPTPGEKPGVLSNFKDSLISRLLADTRTVLGGRSTTEMLAALGKLMPLLRGLGGGVWPQDSNLQNKQASVTTELKKILQGVRRSWHGEVSLDPVLGQAQGPLRKFLDATGDLTQELLNLPSLLELRALLHRPRGSAGSLELISEVLCSTKGPSSPGGLSLNWYDTSQLNEFMDPELAPALPDSSLSPACSKFVGSLNDHPVSLLLWSRLKPLILGKILFTPDTNFTRKLMAQVNRTFEELALLRDLQEVWEVLGPQIFNFMNDSSNMAMLQRLLAVEDLGWRHQTPRGQQKLEAVRDFLDPSRGGYNWQKAHADIGHLAEILGQIMECVSLDKLEAVPSEAALVSRALELLGERRLWAGVVFLSTKDPVDRSELSSPALGPGHLRFKIRMDIDVVTSTDKIRDKFWDPGPSADPFMDLRYVWGGFVYLQDLLEQAAVRVLSGRDSHTGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLSWIYSVALTVKAVVHEKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGDILPYSHPAVLFFFLAAFAVATVAQSFLLSAFFSRANLAAACGGLIYFSLYLPYVLCVAWRERLPKGIRVAASLLSPVAFGFGCESLALLEEQGDGAQWHNLGSDPAEDIFSLAQVSAFLLVDAAIYGLALWYLEAVCPGQYGIPEPWDFPFRRSYWYGPGPPQGSDLAPAPQDPKVLVEEPLPGLIPGVSIRGLKKHFHGCPQPALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSASILGHDVQTNMAAIRPHLGICPQYNVLFDLLTVEEHVWFYGRLKGLSAAAMIPEQEHLIQDVGLILKRDTQTRHLSGGMQRKLSVAIAFVGGSRVVILDEPTAGVDPASRRGIWELLLKYREGRTLILSTHYLDEAELLGDRVAVVASGSLCCCGSPLFLRRRLGSGYYLTLVKSPQSRNIQGSKGNSGKSRQEQKPDSEGSMAGTTLTQETLDGSSQAPTPDAAPITPRTPKILDLVKRHVPEAQLVEELPHELVLALPYTGALDGSFGMVFQELDQQLEALGLTGYGISDTNLEEIFLKVVEDAQREGGDSGQYLHPRTATQQPHTGPEVSALENGELARLMLDPQGLQVFTPNAAPVQGWTLTCQQLRALLHKRFLLAHRSHWGLFAQIVLPALFVGLALLFSLIVPPFSQYPPLQLSPAMYGPQVSFFSEDAPQDPNQVKLLEALLEEAGLHNPSMQGVAARGPKCTHSLDCYFSVPEVPADVAHILALGNWTPESPSPACLCSQPGARRLLPDCPAGAGGPPPPQAIAGLGEVVQNLTGRNVSDFLVKTYSSLVRRGLKTKKWVDEVRYGGFSLGGGDPDLPSGYEVIHTVSEMRALLSPQPGKALDRILNNLTQWALGLDARNNLKIWFNNKGWHAMVAFVNRANNGLLHALLPTGTSHHAHGITTFNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLVSGLPQTLYWLGNFFWDMCNYLVAMCIVVFIFLAFQQRAYVSPQNLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELLSDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMEDAFERLGDKQFQSPLRWDVIGKNLLAMVVQGPLFLLITLILQHRNHLLPQSKPKLLPPLGEEDEDVAQERGRVTKGATTGDVLVLRDLTKVYRGQRSPAVDRLCLGIAPGECFGLLGVNGAGKTSTFRMVTGDTLPSSGEAVLAGHNVAQEPAAAHRSMGYCPQSDAIFDLLTGREHLELFARLRGLPKAQAAQTALSGLVRLGLSSYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLSVVHEGRSVVLTSHSMEECEALCTRLAIMVNGRFRCLGSPQHLKGRFGTGHTLTLMVPPEQPEPTIAFVMATFPGAVLREMHGSRLRFQLPPGGSCTLARVFQELAAQGKDHGVEDFSVSQTTLEEVFLHFSKDQGEEEDNWQETGAWELSTPGLQHPKRVSRFLEDPSSMETVL", "length": 2210, "header": "tr|A0A9J7G2F2-1|A0A9J7G2F2_CRIGR Isoform 1 of Phospholipid-transporting ATPase ABCA7 isoform X1 OS=Cricetulus griseus OX=10029 GN=Abca7 PE=4 SV=1 CANONICAL=A0A9J7G2F2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2/entry#A0A9J7G3K1-1", "sequence": { "sequence": "MKNEDQRQSGIYLEPHSSLSTYCFCCPLCCFPSRVIMAFCTQLMLLLWKNYTYRKRQPIQLLVELLWPLFLFFILVSVRHSHPPLEHHECHFTNKPLPSAGTVPWLQGLICNVNNSCFQQPTPGEKPGVLSNFKDSLISRLLADTRTVLGGRSTTEMLAALGKLMPLLRGLGGGVWPQDSNLQNKQASVTTELKKILQGVRRSWHGEVSLDPVLGQAQGPLRKFLDATGDLTQELLNLPSLLELRALLHRPRGSAGSLELISEVLCSTKGPSSPGGLSLNWYDTSQLNEFMDPELAPALPDSSLSPACSKFVGSLNDHPVSLLLWSRLKPLILGKILFTPDTNFTRKLMAQVNRTFEELALLRDLQEVWEVLGPQIFNFMNDSSNMAMLQRLLAVEDLGWRHQTPRGQQKLEAVRDFLDPSRGGYNWQKAHADIGHLAEILGQIMECVSLDKLEAVPSEAALVSRALELLGERRLWAGVVFLSTKDPVDRSELSSPALGPGHLRFKIRMDIDVVTSTDKIRDKFWDPGPSADPFMDLRYVWGGFVYLQDLLEQAAVRVLSGRDSHTGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLSWIYSVALTVKAVVHEKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKSLLSPVAFGFGCESLALLEEQGDGAQWHNLGSDPAEDIFSLAQVSAFLLVDAAIYGLALWYLEAVCPGQYGIPEPWDFPFRRSYWYGPGPPQGSDLAPAPQDPKVLVEEPLPGLIPGVSIRGLKKHFHGCPQPALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSASILGHDVQTNMAAIRPHLGICPQYNVLFDLLTVEEHVWFYGRLKGLSAAAMIPEQEHLIQDVGLILKRDTQTRHLSGGMQRKLSVAIAFVGGSRVVILDEPTAGVDPASRRGIWELLLKYREGRTLILSTHYLDEAELLGDRVAVVASGSLCCCGSPLFLRRRLGSGYYLTLVKSPQSRNIQGSKGNSGKSRQEQKPDSEGSMAGTTLTQETLDGSSQAPTPDAAPITPRTPKILDLVKRHVPEAQLVEELPHELVLALPYTGALDGSFGMVFQELDQQLEALGLTGYGISDTNLEEIFLKVVEDAQREGGDSGQYLHPRTATQQPHTGPEVSALENGELARLMLDPQGLQVFTPNAAPVQGWTLTCQQLRALLHKRFLLAHRSHWGLFAQIVLPALFVGLALLFSLIVPPFSQYPPLQLSPAMYGPQVSFFSEDAPQDPNQVKLLEALLEEAGLHNPSMQGVAARGPKCTHSLDCYFSVPEVPADVAHILALGNWTPESPSPACLCSQPGARRLLPDCPAGAGGPPPPQAIAGLGEVVQNLTGRNVSDFLVKTYSSLVRRGLKTKKWVDEVRYGGFSLGGGDPDLPSGYEVIHTVSEMRALLSPQPGKALDRILNNLTQWALGLDARNNLKIWFNNKGWHAMVAFVNRANNGLLHALLPTGTSHHAHGITTFNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLVSGLPQTLYWLGNFFWDMCNYLVAMCIVVFIFLAFQQRAYVSPQNLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELLSDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMEDAFERLGDKQFQSPLRWDVIGKNLLAMVVQGPLFLLITLILQHRNHLLPQSKPKLLPPLGEEDEDVAQERGRVTKGATTGDVLVLRDLTKVYRGQRSPAVDRLCLGIAPGECFGLLGVNGAGKTSTFRMVTGDTLPSSGEAVLAGHNVAQEPAAAHRSMGYCPQSDAIFDLLTGREHLELFARLRGLPKAQAAQTALSGLVRLGLSSYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLSVVHEGRSVVLTSHSMEECEALCTRLAIMVNGRFRCLGSPQHLKGRFGTGHTLTLMVPPEQPEPTIAFVMATFPGAVLREMHGSRLRFQLPPGGSCTLARVFQELAAQGKDHGVEDFSVSQTTLEEVFLHFSKDQGEEEDNWQETGAWELSTPGLQHPKRVSRFLEDPSSMETVL", "length": 2136, "header": "tr|A0A9J7G3K1-1|A0A9J7G3K1_CRIGR Computationally mapped isoform of Phospholipid-transporting ATPase ABCA7 isoform X5 OS=Cricetulus griseus OX=10029 GN=Abca7 PE=4 SV=1 CANONICAL=A0A9J7G2F2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G5I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2/entry#A0A9J7G5I4-1", "sequence": { "sequence": "MAFCTQLMLLLWKNYTYRKRQPIQLLVELLWPLFLFFILVSVRHSHPPLEHHECHFTNKPLPSAGTVPWLQGLICNVNNSCFQQPTPGEKPGVLSNFKDSLISRLLADTRTVLGGRSTTEMLAALGKLMPLLRGLGGGVWPQDSNLQNKQASVTTELKKILQGVRRSWHGEVSLDPVLGQAQGPLRKFLDATGDLTQELLNLPSLLELRALLHRPRGSAGSLELISEVLCSTKGPSSPGGLSLNWYDTSQLNEFMDPELAPALPDSSLSPACSKFVGSLNDHPVSLLLWSRLKPLILGKILFTPDTNFTRKLMAQVNRTFEELALLRDLQEVWEVLGPQIFNFMNDSSNMAMLQRLLAVEDLGWRHQTPRGQQKLEAVRDFLDPSRGGYNWQKAHADIGHLAEILGQIMECVSLDKLEAVPSEAALVSRALELLGERRLWAGVVFLSTKDPVDRSELSSPALGPGHLRFKIRMDIDVVTSTDKIRDKFWDPGPSADPFMDLRYVWGGFVYLQDLLEQAAVRVLSGRDSHTGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLSWIYSVALTVKAVVHEKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGDILPYSHPAVLFFFLAAFAVATVAQSFLLSAFFSRANLAAACGGLIYFSLYLPYVLCVAWRERLPKGIRVAASLLSPVAFGFGCESLALLEEQGDGAQWHNLGSDPAEDIFSLAQVSAFLLVDAAIYGLALWYLEAVCPGQYGIPEPWDFPFRRSYWYGPGPPQGSDLAPAPQDPKVLVEEPLPGLIPGVSIRGLKKHFHGCPQPALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSASILGHDVQTNMAAIRPHLGICPQYNVLFDLLTVEEHVWFYGRLKGLSAAAMIPEQEHLIQDVGLILKRDTQTRHLSGGMQRKLSVAIAFVGGSRVVILDEPTAGVDPASRRGIWELLLKYREGRTLILSTHYLDEAELLGDRVAVVASGSLCCCGSPLFLRRRLGSGYYLTLVKSPQSRNIQGSKGNSGKSRQEQKPDSEGSMAGTTLTQETLDGSSQAPTPDAAPITPRTPKILDLVKRHVPEAQLVEELPHELVLALPYTGALDGSFGMVFQELDQQLEALGLTGYGISDTNLEEIFLKVVEDAQREGGDSGQYLHPRTATQQPHTGPEVSALENGELARLMLDPQGLQVFTPNAAPVQGWTLTCQQLRALLHKRFLLAHRSHWGLFAQIVLPALFVGLALLFSLIVPPFSQYPPLQLSPAMYGPQVSFFSEDAPQDPNQVKLLEALLEEAGLHNPSMQGVAARGPKCTHSLDCYFSVPEVPADVAHILALGNWTPESPSPACLCSQPGARRLLPDCPAGAGGPPPPQAIAGLGEVVQNLTGRNVSDFLVKTYSSLVRRGLKTKKWVDEVRYGGFSLGGGDPDLPSGYEVIHTVSEMRALLSPQPGKALDRILNNLTQWALGLDARNNLKIWFNNKGWHAMVAFVNRANNGLLHALLPTGTSHHAHGITTFNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLVSGLPQTLYWLGNFFWDMCNYLVAMCIVVFIFLAFQQRAYVSPQNLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELLSDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMEDAFERLGDKQFQSPLRWDVIGKNLLAMVVQGPLFLLITLILQHRNHLLPQSKPKLLPPLGEEDEDVAQERGRVTKGATTGDVLVLRDLTKVYRGQRSPAVDRLCLGIAPGECFGLLGVNGAGKTSTFRMVTGDTLPSSGEAVLAGHNVAQEPAAAHRSMGYCPQSDAIFDLLTGREHLELFARLRGLPKAQAAQTALSGLVRLGLSSYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLSVVHEGRSVVLTSHSMEECEALCTRLAIMVNGRFRCLGSPQHLKGRFGTGHTLTLMVPPEQPEPTIAFVMATFPGAVLREMHGSRLRFQLPPGGSCTLARVFQELAAQGKDHGVEDFSVSQTTLEEVFLHFSKDQGEEEDNWQETGAWELSTPGLQHPKRVSRFLEDPSSMETVL", "length": 2174, "header": "tr|A0A9J7G5I4-1|A0A9J7G5I4_CRIGR Computationally mapped isoform of Phospholipid-transporting ATPase ABCA7 isoform X4 OS=Cricetulus griseus OX=10029 GN=Abca7 PE=4 SV=1 CANONICAL=A0A9J7G2F2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2/entry#A0A9J7G6R6-1", "sequence": { "sequence": "MKNEDQRQSGIYLEPHSSLSTYCFCCPLCCFPSRVIMAFCTQLMLLLWKNYTYRKRQPIQLLVELLWPLFLFFILVSVRHSHPPLEHHECHFTNKPLPSAGTVPWLQGLICNVNNSCFQQPTPGEKPGVLSNFKDSLISRLLADTRTVLGGRSTTEMLAALGKLMPLLRGLGGGVWPQDSNLQNKQASVTTELKKILQGVSLDPVLGQAQGPLRKFLDATGDLTQELLNLPSLLELRALLHRPRGSAGSLELISEVLCSTKGPSSPGGLSLNWYDTSQLNEFMDPELAPALPDSSLSPACSKFVGSLNDHPVSLLLWSRLKPLILGKILFTPDTNFTRKLMAQVNRTFEELALLRDLQEVWEVLGPQIFNFMNDSSNMAMLQRLLAVEDLGWRHQTPRGQQKLEAVRDFLDPSRGGYNWQKAHADIGHLAEILGQIMECVSLDKLEAVPSEAALVSRALELLGERRLWAGVVFLSTKDPVDRSELSSPALGPGHLRFKIRMDIDVVTSTDKIRDKFWDPGPSADPFMDLRYVWGGFVYLQDLLEQAAVRVLSGRDSHTGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLSWIYSVALTVKAVVHEKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGDILPYSHPAVLFFFLAAFAVATVAQSFLLSAFFSRANLAAACGGLIYFSLYLPYVLCVAWRERLPKGIRVAASLLSPVAFGFGCESLALLEEQGDGAQWHNLGSDPAEDIFSLAQVSAFLLVDAAIYGLALWYLEAVCPGQYGIPEPWDFPFRRSYWYGPGPPQGSDLAPAPQDPKVLVEEPLPGLIPGVSIRGLKKHFHGCPQPALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSASILGHDVQTNMAAIRPHLGICPQYNVLFDLLTVEEHVWFYGRLKGLSAAAMIPEQEHLIQDVGLILKRDTQTRHLSGGMQRKLSVAIAFVGGSRVVILDEPTAGVDPASRRGIWELLLKYREGRTLILSTHYLDEAELLGDRVAVVASGSLCCCGSPLFLRRRLGSGYYLTLVKSPQSRNIQGSKGNSGKSRQEQKPDSEGSMAGTTLTQETLDGSSQAPTPDAAPITPRTPKILDLVKRHVPEAQLVEELPHELVLALPYTGALDGSFGMVFQELDQQLEALGLTGYGISDTNLEEIFLKVVEDAQREGGDSGQYLHPRTATQQPHTGPEVSALENGELARLMLDPQGLQVFTPNAAPVQGWTLTCQQLRALLHKRFLLAHRSHWGLFAQIVLPALFVGLALLFSLIVPPFSQYPPLQLSPAMYGPQVSFFSEDAPQDPNQVKLLEALLEEAGLHNPSMQGVAARGPKCTHSLDCYFSVPEVPADVAHILALGNWTPESPSPACLCSQPGARRLLPDCPAGAGGPPPPQAIAGLGEVVQNLTGRNVSDFLVKTYSSLVRRGLKTKKWVDEVRYGGFSLGGGDPDLPSGYEVIHTVSEMRALLSPQPGKALDRILNNLTQWALGLDARNNLKIWFNNKGWHAMVAFVNRANNGLLHALLPTGTSHHAHGITTFNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLVSGLPQTLYWLGNFFWDMCNYLVAMCIVVFIFLAFQQRAYVSPQNLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELLSDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMEDAFERLGDKQFQSPLRWDVIGKNLLAMVVQGPLFLLITLILQHRNHLLPQSKPKLLPPLGEEDEDVAQERGRVTKGATTGDVLVLRDLTKVYRGQRSPAVDRLCLGIAPGECFGLLGVNGAGKTSTFRMVTGDTLPSSGEAVLAGHNVAQEPAAAHRSMGYCPQSDAIFDLLTGREHLELFARLRGLPKAQAAQTALSGLVRLGLSSYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLSVVHEGRSVVLTSHSMEECEALCTRLAIMVNGRFRCLGSPQHLKGRFGTGHTLTLMVPPEQPEPTIAFVMATFPGAVLREMHGSRLRFQLPPGGSCTLARVFQELAAQGKDHGVEDFSVSQTTLEEVFLHFSKDQGEEEDNWQETGAWELSTPGLQHPKRVSRFLEDPSSMETVL", "length": 2202, "header": "tr|A0A9J7G6R6-1|A0A9J7G6R6_CRIGR Computationally mapped isoform of Phospholipid-transporting ATPase ABCA7 isoform X2 OS=Cricetulus griseus OX=10029 GN=Abca7 PE=4 SV=1 CANONICAL=A0A9J7G2F2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2/entry#A0A9J7G7Y4-1", "sequence": { "sequence": "MKNEDQRQSGIYLEPHSSLSTYCFCCPLCCFPSRVIMAFCTQLMLLLWKNYTYRKRQPIQLLVELLWPLFLFFILVSVRHSHPPLEHHECHFTNKPLPSAGTVPWLQGLICNVNNSCFQQPTPGEKPGVLSNFKDSLISRLLADTRTVLGGRSTTEMLAALGKLMPLLRGLGGGVWPQDSNLQNKQASVTTELKKILQGVRRSWHGEVSLDPVLGQAQGPLRKFLDATGDLTQELLNLPSLLELRALLHRPRGSAGSLELISEVLCSTKGPSSPGGLSLNWYDTSQLNEFMDPELAPALPDSSLSPACSKFVGSLNDHPVSLLLWSRLKPLILGKILFTPDTNFTRKLMAQVNRTFEELALLRDLQEVWEVLGPQIFNFMNDSSNMAMLQRLLAVEDLGWRHQTPRGQQKLEAVRDFLDPSRGGYNWQKAHADIGHLAEILGQIMECVSLDKLEAVPSEAALVSRALELLGERRLWAGVVFLSTKDPVDRSELSSPALGPGHLRFKIRMDIDVVTSTDKIRDKFWDPGPSADPFMDLRYVWGGFVYLQDLLEQAAVRVLSGRDSHTGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLSWIYSVALTVKAVVHEKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGDILPYSHPAVLFFFLAAFAVATVAQSFLLSAFFSRANLAAACGGLIYFSLYLPYVLCVAWRERLPKGIRVAASLLSPVAFGFGCESLALLEEQGDGAQWHNLGSDPAEDIFSLAQVSAFLLVDAAIYGLALWYLEAVCPGQYGIPEPWDFPFRRSYWYGPGPPQGSDLAPAPQDPKVLVEEPLPGLIPGVSIRGLKKHFHGCPQPALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSASILGHDVQTNMAAIRPHLGICPQYNVLFDLLTVEEHVWFYGRLKGLSAAAMIPEQEHLIQDVGLILKRDTQTRHLSGGMQRKLSVAIAFVGGSRVVILDEPTAGVDPASRRGIWELLLKYREGRTLILSTHYLDEAELLGDRVAVVASGSLCCCGSPLFLRRRLGSGYYLTLVKSPQSRNIQGSKGNSGKSRQEQKPDSEGSMAGTTLTQETLDGSSQAPTPDAAPITPRTPKILDLVKRHVPEAQLVEELPHELVLALPYTGALDGSFGMVFQELDQQLEALGLTGYGISDTNLEEIFLKVVEDAQREGGDSGQYLHPRTATQQPHTGPEVSALENGELARLMLDPQGLQVFTPNAAPVQGWTLTCQQLRALLHKRFLLAHRSHWGLFAQIVLPALFVGLALLFSLIVPPFSQYPPLQLSPAMYGPQVSFFSEDAPQDPNQVKLLEALLEEAGLHNPSMQGVAARGPKCTHSLDCYFSVPEVPADVAHILALGNWTPESPSPACLCSQPGARRLLPDCPAGAGGPPPPQAIAGLGEVVQNLTGRNVSDFLVKTYSSLVRRGLKTKKWVDEVRYGGFSLGGGDPDLPSGYEVIHTVSEMRALLSPQPGKALDRILNNLTQWALGLDARNNLKIWFNNKGWHAMVAFVNRANNGLLHALLPTGTSHHAHGITTFNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLVSGLPQTLYWLGNFFWDMCNYLVAMCIVVFIFLAFQQRAYVSPQNLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELLSDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMEDAFERLGDKQFQSPLRWDVIGKNLLAMVVQGPLFLLITLILQHRNHLLPQSKPKLLPPLGEEDEDVAQERGRVTKGATTGDVLVLRDLTKVYRGQRSPAVDRLCLGIAPGECFGLLGVNGAGKTSTFRMVTGDTLPSSGEAVLAGHKHPCNPVWVVHKDLSILFPTAV", "length": 1944, "header": "tr|A0A9J7G7Y4-1|A0A9J7G7Y4_CRIGR Computationally mapped isoform of Phospholipid-transporting ATPase ABCA7 isoform X6 OS=Cricetulus griseus OX=10029 GN=Abca7 PE=3 SV=1 CANONICAL=A0A9J7G2F2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2/entry#A0A9J7JTU7-1", "sequence": { "sequence": "MKNEDQRQSGIYLEPHSSLSTYCFCCPLCCFPSRVIMAFCTQLMLLLWKNYTYRKRQPIQLLVELLWPLFLFFILVSVRHSHPPLEHHECHFTNKPLPSAGTVPWLQGLICNVNNSCFQQPTPGEKPGVLSNFKDSLISRLLADTRTVLGGRSTTEMLAALGKLMPLLRGLGGGVWPQDSNLQNKQASVTTELKKILQGVRRSWHGEVSLDPVLGQAQGPLRKFLDATGDLTQELLNLPSLLELRALLHRPRGSAGSLELISEVLCSTKGPSSPGGLSLNWYDTSQLNEFMDPELAPALPDSSLSPACSKFVGSLNDHPVSLLLWSRLKPLILGKILFTPDTNFTRKLMAQVNRTFEELALLRDLQEVWEVLGPQIFNFMNDSSNMAMLQRLLAVEDLGWRHQTPRGQQKLEAVRDFLDPSRGGYNWQKAHADIGHLAEILGQIMECVSLDKLEAVPSEAALVSRALELLGERRLWAGVVFLSTKDPVDRSELSSPALGPGHLRFKIRMDIDVVTSTDKIRDKFWDPGPSADPFMDLRYVWGGFVYLQDLLEQAAVRVLSGRDSHTGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLSWIYSVALTVKAVVHEKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGDILPYSHPAVLFFFLAAFAVATVAQSFLLSAFFSRANLAAACGGLIYFSLYLPYVLCVAWRERLPKGIRVAASLLSPVAFGFGCESLALLEEQGDGAQWHNLGSDPAEDIFSLAQVSAFLLVDAAIYGLALWYLEAVCPGQYGIPEPWDFPFRRSYWYGPGPPQGSDLAPAPQDPKVLVEEPLPGLIPGVSIRGLKKHFHGCPQPALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSASILGHDVQTNMAAIRPHLGICPQYNVLFDLLTVEEHVWFYGRLKGLSAAAMIPEQEHLIQDVGLILKRDTQTRHLSGGMQRKLSVAIAFVGGSRVVILDEPTAGVDPASRRGIWELLLKYREGRTLILSTHYLDEAELLGDRVAVVASGSLCCCGSPLFLRRRLGSGYYLTLVKSPQSRNIQGSKGNSGKSRQEQKPDSEGSMAGTTLTQETLDGSSQAPTPDAAPITPRTPKILDLVKRHVPEAQLVEELPHELVLALPYTGALDGSFGMVFQELDQQLEALGLTGYGISDTNLEEIFLKVVEDAQREGGDSGQYLHPRTATQQPHTGPEVSALENGELARLMLDPQGLQVFTPNAAPVQGWTLTCQQLRALLHKRFLLAHRSHWGLFAQIVLPALFVGLALLFSLIVPPFSQYPPLQLSPAMYGPQVSFFSEDAPQDPNQVKLLEALLEEAGLHNPSMQGVAARGPKCTHSLDCYFSVPEVPADVAHILALGNWTPESPSPACLCSQPGARRLLPDCPAGAGGPPPPQAIAGLGEVVQNLTGRNVSDFLVKTYSSLVRRGLKTKKWVDEVRYGGFSLGGGDPDLPSGYEVIHTVSEMRALLSPQPGKALDRILNNLTQWALGLDARNNLKIWFNNKGWHAMVAFVNRANNGLLHALLPTGTSHHAHGITTFNHPLNLTKEQLSEAALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLVSGLPQTLYWLGNFFWDMCNYLVAMCIVVFIFLAFQQRAYVSPQNLPALLLLLLLYGTAYVVLTCINLFIGINSSMATFVLELLSDQKLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMEDAFERLGDKQFQSPLRWDVIGKNLLAMVVQGPLFLLITLILQHRNHLLPQSKPKLLPPLGEEDEDVAQERGRVTKGATTGDVLVLRDLTKVYRGQRSPAVDRLCLGIAPGECFGLLGVNGAGKTSTFRMVTGDTLPSSGEAVLAGHNVAQEPAAAHRSMGYCPQSDAIFDLLTGREHLELFARLRGLPKAQAAQTALSGLVRLGLSSYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLSVVHEGRSVVLTSHSMEECEALCTRLAIMVNGRFRCLGSPQHLKGRFGTGHTLTLMVPPEQPEPTIAFVMATFPGAVLREMHGSRLRFQLPPGGSCTLARVFQELAAQGKDHGVEDFSVSQTTLEEVFLHFSKDQGEEEDNWQETGAWELSTPGLQHPKRVSRFLEDPSSMETVL", "length": 2192, "header": "tr|A0A9J7JTU7-1|A0A9J7JTU7_CRIGR Computationally mapped isoform of Phospholipid-transporting ATPase ABCA7 isoform X3 OS=Cricetulus griseus OX=10029 GN=Abca7 PE=4 SV=1 CANONICAL=A0A9J7G2F2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1127, "start_aa": "Thr", "end_pos": 1127, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1127", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 122, "start_aa": "Thr", "end_pos": 122, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr122", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764464", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764464", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 7, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "pmid": "" }, { "name": "apolipoprotein A-I receptor activity", "id": "GO:0034188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034188", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "pmid": "" }, { "name": "phosphatidylcholine floppase activity", "id": "GO:0090554", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090554", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "pmid": "" }, { "name": "phosphatidylserine floppase activity", "id": "GO:0090556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "pmid": "" }, { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phospholipid efflux", "id": "GO:0033700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2F2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2F2" } ], "pmid": "" }, { "name": "cholesterol efflux", "id": 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Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027275257.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275257" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bsg", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7", "locus": {} } ], "crossref": [ { "id": "A0A9J7G2H7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G2H7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100689246", "url": "https://www.ncbi.nlm.nih.gov/gene/100689246", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100689246", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100689246", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G2H7", "url": "https://www.orthodb.org/?gene=A0A9J7G2H7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275257", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G2H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAPLPPSLLIERRSGAALGRGDMAAALLLALGFALLCGQGACAAAGTVVTSINDVGSKTHLTCSLNSSGVDIIGHRWMRGGKILQEDTLPDLQTQYTVDIDDRSGDYACIFLPEPVGRSNIVVEGPPRIKVGKKSEHSSEGENVRLICKSESSHPPVTEWSWFKTSDSGDQLITNSSESKYVVISTADRSELTISNLDINSDPGTYMCNATNTQGSVQEIMTLRVRSRLAALWPFLGIVAEVLVLVTIIFIYEKRRKPDQTLDEDDPGAAPLKGSGHHMNDKDKNVRQRNAT", "length": 293, "header": "tr|A0A9J7G2H7-1|A0A9J7G2H7_CRIGR Isoform 1 of Basigin OS=Cricetulus griseus OX=10029 GN=Bsg PE=4 SV=1 CANONICAL=A0A9J7G2H7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G2H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7/entry#A0A9J7G2H7-1", "sequence": { "sequence": "MRAPLPPSLLIERRSGAALGRGDMAAALLLALGFALLCGQGACAAAGTVVTSINDVGSKTHLTCSLNSSGVDIIGHRWMRGGKILQEDTLPDLQTQYTVDIDDRSGDYACIFLPEPVGRSNIVVEGPPRIKVGKKSEHSSEGENVRLICKSESSHPPVTEWSWFKTSDSGDQLITNSSESKYVVISTADRSELTISNLDINSDPGTYMCNATNTQGSVQEIMTLRVRSRLAALWPFLGIVAEVLVLVTIIFIYEKRRKPDQTLDEDDPGAAPLKGSGHHMNDKDKNVRQRNAT", "length": 293, "header": "tr|A0A9J7G2H7-1|A0A9J7G2H7_CRIGR Isoform 1 of Basigin OS=Cricetulus griseus OX=10029 GN=Bsg PE=4 SV=1 CANONICAL=A0A9J7G2H7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100689246", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100689246", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2H7" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": 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"type": "recommended", "evidence": [ { "id": "A0A9J7G2I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2I4/entry#names_and_taxonomy" } ] }, { "name": "3.6.1.7", "type": "synonym", "evidence": [ { "id": "A0A9J7G2I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2I4/entry#names_and_taxonomy" } ] }, { "name": "acylphosphatase-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007641576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641576" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613913.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007641576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641576" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2I4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2I4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Acyp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2I4", "locus": {} } ], "crossref": [ { "id": "A0A9J7G2I4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G2I4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100755378", "url": "https://www.ncbi.nlm.nih.gov/gene/100755378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001792", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001792", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755378", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G2I4", "url": "https://www.orthodb.org/?gene=A0A9J7G2I4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JJR2", "url": "https://www.orthodb.org/?gene=A0A9J7JJR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10029", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10029", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10029:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10029:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00708", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00708", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007641576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14965", "url": "https://www.rhea-db.org/rhea/14965", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G2I4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2I4-1", 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MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613783.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003500303.1. 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G2S2-1", "uniprot_ac": "A0A9J7G2S2", "uniprot_id": "A0A9J7G2S2_CRIGR", "mass": { "chemical_mass": 42991.0, "monoisotopic_mass": 42991.0 }, "refseq": { "ac": "XP_003500163", "name": "LIM/homeobox protein Lhx4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500163" }, "gene_names": [ { "name": "Lhx4", "type": "recommended", "evidence": [ { "id": "A0A9J7G2S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2" } ] }, { "name": "Lhx4", "type": "synonym", "evidence": [ { "id": "XP_003500163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500163" } ] } ], "protein_names": [ { "name": "LIM/homeobox protein Lhx4", "type": "synonym", "evidence": [ { "id": "XP_003500163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500163" }, { "id": "A0A9J7G2S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613774.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003500163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500163" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lhx4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2", "locus": {} } ], "crossref": [ { "id": "A0A9J7G2S2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G2S2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09376", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09376", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09468", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09468", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750849", "url": "https://www.ncbi.nlm.nih.gov/gene/100750849", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750849", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750849", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GLDYTMD", "url": "https://omabrowser.org/oma/group/GLDYTMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G2S2", "url": "https://www.orthodb.org/?gene=A0A9J7G2S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24208:SF116", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24208:SF116", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003500163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500163", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G2S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQSAAVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLVDRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGGSKQGKESSAEDCGVSDSELSFQEDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGVIAHAGQGVSQTLRAMAGGPTSDLSTGSSVGYPDFPTSPASWLDEMDHPPF", "length": 390, "header": "tr|A0A9J7G2S2-1|A0A9J7G2S2_CRIGR Isoform 1 of LIM/homeobox protein Lhx4 OS=Cricetulus griseus OX=10029 GN=Lhx4 PE=4 SV=1 CANONICAL=A0A9J7G2S2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G2S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2/entry#A0A9J7G2S2-1", "sequence": { "sequence": "MMQSAAVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLVDRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGGSKQGKESSAEDCGVSDSELSFQEDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGVIAHAGQGVSQTLRAMAGGPTSDLSTGSSVGYPDFPTSPASWLDEMDHPPF", "length": 390, "header": "tr|A0A9J7G2S2-1|A0A9J7G2S2_CRIGR Isoform 1 of LIM/homeobox protein Lhx4 OS=Cricetulus griseus OX=10029 GN=Lhx4 PE=4 SV=1 CANONICAL=A0A9J7G2S2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 360, "start_aa": "Thr", "end_pos": 360, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr360", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750849", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750849", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0S5S7-1", "protein_name": "LIM/homeobox protein Lhx4", "gene_name": "lhx4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKMMQSAAVLPGESAVKGLPDILGVPLQQIPQCAGCSQHILDKFILKVLDRHWHSKCLKCADCHALLADKCFSRAGNVYCKEDFFKRFGTKCASCQQGIPPTQVVRKAQDFVYHLHCFACVMCSRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSETGAKRPRTTITAKQLETLKSAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRNRGSSKTEKESSADDAGLSDSELSFRDDQILSDLGHANGLYGSVGDVSNGNMLNGSFSLDGGGQPYHDLRAGSPYGLPQSPSSITSLPGHTPLLNNLGFSMDGLMGQAGQPSVGQALRAMAGGPTSDLSTGSSTGYPDFPTSPASWLDEMDHSQF", "length": 391 }, "evidence": [ { "id": "A0A9J7G2S2", "url": "https://omabrowser.org/oma/group/A0A9J7G2S2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LZ08-1", "protein_name": "LIM homeobox 4", "gene_name": "Lhx4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMQSAAVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGGSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLSGLDYTVDSNLGVIAHPGQGVSQTLRAMAGGPTSDLSTGSSVGYPDFPTSPASWLDEMDHPPF", "length": 390 }, "evidence": [ { "id": "A0A9J7G2S2", "url": "https://omabrowser.org/oma/group/A0A9J7G2S2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MFM7-1", "protein_name": "LIM homeobox 4", "gene_name": "LHX4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMQSAAVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGGSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVSGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDISTGSSVGYPDFPTSPASWLDEMDHPPF", "length": 390 }, "evidence": [ { "id": "A0A9J7G2S2", "url": "https://omabrowser.org/oma/group/A0A9J7G2S2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S681-1", "protein_name": "LIM homeobox 4", "gene_name": "LHX4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMQSAAVPAEGAVKGLSEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLPCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIVAHAGQGGSQTLRAMAGGPTSDISTGSSVGYPDFPTSPASWLDEMDHPPF", "length": 390 }, "evidence": [ { "id": "A0A9J7G2S2", "url": "https://omabrowser.org/oma/group/A0A9J7G2S2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P53776-1", "protein_name": "LIM/homeobox protein Lhx4", "gene_name": "Lhx4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMQSAAVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGGSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDLSTGSSVGYPDFPTSPASWLDEMDHPPF", "length": 390 }, "evidence": [ { "id": "A0A9J7G2S2", "url": "https://omabrowser.org/oma/group/A0A9J7G2S2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q969G2-1", "protein_name": "LIM/homeobox protein Lhx4", "gene_name": "LHX4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQSATVPAEGAVKGLPEMLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCKEDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRLVCKEDYETAKQNDDSEAGAKRPRTTITAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRHRWGQFYKSVKRSRGSSKQEKESSAEDCGVSDSELSFREDQILSELGHTNRIYGNVGDVTGGQLMNGSFSMDGTGQSYQDLRDGSPYGIPQSPSSISSLPSHAPLLNGLDYTVDSNLGIIAHAGQGVSQTLRAMAGGPTSDISTGSSVGYPDFPTSPGSWLDEMDHPPF", "length": 390 }, "evidence": [ { "id": "A0A9J7G2S2", "url": "https://omabrowser.org/oma/group/A0A9J7G2S2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2" } ], "pmid": "" }, { "name": "placenta development", "id": "GO:0001890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001890", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S2" } ], "pmid": "" }, { "name": "motor neuron 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isoform of Interferon-activable protein 204 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100758550 PE=3 SV=1 CANONICAL=A0A9J7G2S5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 176, "start_aa": "Thr", "end_pos": 176, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr176", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758550", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758550", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S5" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2S5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2S5" } ], "pmid": "" }, { "name": "cellular response to interferon-beta", "id": 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Required for centriole subdistal appendage assembly.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9#function" }, { "database": "UniProtKB", "id": "ARBA00053332", "url": "https://www.uniprot.org/uniprotkb/ARBA00053332#function" }, { "database": "UniProtKB", "id": "A0A9J7G5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Z8#function" }, { "database": "UniProtKB", "id": "A0A9J7JTG8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTG8#function" }, { "database": "UniProtKB", "id": "A0A9J7K9M4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9M4#function" }, { "database": "UniProtKB", "id": "A0A9J7H2B5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2B5#function" }, { "database": "UniProtKB", "id": "A0A9J7GX47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX47#function" }, { "database": "UniProtKB", "id": "A0A9J7GYA9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYA9#function" }, { "database": "UniProtKB", "id": "A0A9J7GZ39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZ39#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cep170", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9", "locus": {} } ], "crossref": [ { "id": "cd22724", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22724", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771665", "url": "https://www.ncbi.nlm.nih.gov/gene/100771665", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771665", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771665", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XINAMID", "url": "https://omabrowser.org/oma/group/XINAMID/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G2T9", "url": "https://www.orthodb.org/?gene=A0A9J7G2T9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G5Z8", "url": "https://www.orthodb.org/?gene=A0A9J7G5Z8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GZ39", "url": "https://www.orthodb.org/?gene=A0A9J7GZ39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H2B5", "url": "https://www.orthodb.org/?gene=A0A9J7H2B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JTG8", "url": "https://www.orthodb.org/?gene=A0A9J7JTG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7K9M4", "url": "https://www.orthodb.org/?gene=A0A9J7K9M4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15715", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15715", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15715:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15715:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15308", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15308", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007638776", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638776", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G2T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GX47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GX47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYA9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZ39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZ39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZ39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZ39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2B5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTG8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9M4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9M4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYEASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVDATTEVPHRATEALKSEEKSMDVSAMPRGTPLYGQPSWWGDDEVDEQRAFKSNGKPEEKNHETGTSGCSIDAKQAEEQSAAANEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHIAGAGHASFTIEFDDSMPGKVTIRDHVTKFTSDHRHKSKKATPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKTQSTEKHQDQAVTSSTHHRGGHGVPHGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPIINEKHKGLVKDWALNSAAVVMEERKPFSTPGFHNSEEGMSSSGSKRWVSQWASLAANHTRHDPEERLMGLSATVENETNTGEVGISLRSTSSAASLASQGERKRRTLPQLPNEEKPLENSRAKVVPQRSEIGEKQDTELQEKEAAAQVHQNEKRAAAKSLSQVDRPVNGEIPNTGGDNKALPPSGSSSSKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKLSSKSASGHIDKYREESSKQESQLVEKLSGHSTSKGERVIQNESKRRKAEEIPKSQTSKGDKKESSKPLVRQGSFTIEKPSSNIPIELIPHINKQNSSAPTSLALASASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDATKSGTREKIEKKAKSRSTDIGARADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRNPLTSADEHNIHSKLEGGKGTKSKTSPVASGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPIGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRTRANSISRLSDSKVKSVTSTHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSCDSRPQAAETPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHTSPGQTPALCPPETRALDPAAAAASAEFDNAESEADFSIHFNRFNPDGEEEDVVVHE", "length": 1586, "header": "tr|A0A9J7G2T9-1|A0A9J7G2T9_CRIGR Isoform 1 of Centrosomal protein of 170 kDa OS=Cricetulus griseus OX=10029 GN=Cep170 PE=3 SV=1 CANONICAL=A0A9J7G2T9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G2T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9/entry#A0A9J7G2T9-1", "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYEASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVDATTEVPHRATEALKSEEKSMDVSAMPRGTPLYGQPSWWGDDEVDEQRAFKSNGKPEEKNHETGTSGCSIDAKQAEEQSAAANEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHIAGAGHASFTIEFDDSMPGKVTIRDHVTKFTSDHRHKSKKATPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKTQSTEKHQDQAVTSSTHHRGGHGVPHGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPIINEKHKGLVKDWALNSAAVVMEERKPFSTPGFHNSEEGMSSSGSKRWVSQWASLAANHTRHDPEERLMGLSATVENETNTGEVGISLRSTSSAASLASQGERKRRTLPQLPNEEKPLENSRAKVVPQRSEIGEKQDTELQEKEAAAQVHQNEKRAAAKSLSQVDRPVNGEIPNTGGDNKALPPSGSSSSKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKLSSKSASGHIDKYREESSKQESQLVEKLSGHSTSKGERVIQNESKRRKAEEIPKSQTSKGDKKESSKPLVRQGSFTIEKPSSNIPIELIPHINKQNSSAPTSLALASASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDATKSGTREKIEKKAKSRSTDIGARADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRNPLTSADEHNIHSKLEGGKGTKSKTSPVASGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPIGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRTRANSISRLSDSKVKSVTSTHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSCDSRPQAAETPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHTSPGQTPALCPPETRALDPAAAAASAEFDNAESEADFSIHFNRFNPDGEEEDVVVHE", "length": 1586, "header": "tr|A0A9J7G2T9-1|A0A9J7G2T9_CRIGR Isoform 1 of Centrosomal protein of 170 kDa OS=Cricetulus griseus OX=10029 GN=Cep170 PE=3 SV=1 CANONICAL=A0A9J7G2T9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G5Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9/entry#A0A9J7G5Z8-1", "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYEASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVDATTEVPHRATEALKSEEKSMDVSAMPRGTPLYGQPSWWGDDEVDEQRAFKSNGKPEEKNHETGTSGCSIDAKQAEEQSAAANEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHIAGAGHASFTIEFDDSMPGKVTIRDHVTKFTSDHRHKSKKATPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKTQSTEKHQDQAVTSSTHHRGGHGVPHGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPIINEKHKGLVKDWALNSAAVVMEERKPFSTPGFHNSEEGMSSSGSKRWVSQWASLAANHTRHDPEERLMGLSATVENETNTGEVGISLRSTSSAASLASQGERKRRTLPQLPNEEKPLENSRAKVVPQRSEIGEKQDTELQEKEAAAQVHQNEKRAAAKSLSQVDRPVNGEIPNTGGDNKALPPSGSSSSKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKLSSKSASGHIDKYREESSKQESQLVEKLSGHSTSKGERVIQNESKRRKAEEIPKSQTSKGDKKESSKPLVRQGSFTIEKPSSNIPIELIPHINKQNSSAPTSLALASASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDATKSGTREKIEKKAKSRSTDIGARADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRNPLTSADEHNIHSKLEGGKGTKSKTSPVASGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPIGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRTRANSISRLSDSKVKSVTSTHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSCDSRPQAAETPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHTSPGQTPALCPPETRALDPAAAAASAEFDNAESEADFSIHFNRFNPDGEEEDVVVHE", "length": 1559, "header": "tr|A0A9J7G5Z8-1|A0A9J7G5Z8_CRIGR Computationally mapped isoform of Centrosomal protein of 170 kDa OS=Cricetulus griseus OX=10029 GN=Cep170 PE=3 SV=1 CANONICAL=A0A9J7G2T9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GX47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9/entry#A0A9J7GX47-1", "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYEASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVDATTEVPHRATEALKSEEKSMDVSAMPRGTPLYGQPSWWGDDEVDEQRAFKSNGKPEEKNHETGTSGCSIDAKQAEEQSAAANEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHIAGAGHASFTIEFDDSMPGKVTIRDHVTKFTSDHRHKSKKATPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKTQSTEKHQDQAVVFGVDDNQDYNRPIINEKHKGLVKDWALNSAAVVMEERKPFSTPGFHNSEEGMSSSGSKRWVSQWASLAANHTRHDPEERLMGLSATVENETNTGEVGISLRSTSSAASLASQGERKRRTLPQLPNEEKPLENSRAKVVPQRSEIGEKQDTELQEKEAAAQVHQNEKRAAAKSLSQVDRPVNGEIPNTGGDNKALPPSGSSSSKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKLSSKSASGHIDKYREESSKQESQLVEKLSGHSTSKGERVIQNESKRRKAEEIPKSQTSKGDKKESSKPLVRQGSFTIEKPSSNIPIELIPHINKQNSSAPTSLALASASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDATKSGTREKIEKKAKSRSTDIGARADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRNPLTSADEHNIHSKLEGGKGTKSKTSPVASGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPIGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRTRANSISRLSDSKVKSVTSTHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSCDSRPQAAETPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHTSPGQTPALCPPETRALDPAAAAASAEFDNAESEADFSIHFNRFNPDGEEEDVVVHE", "length": 1488, "header": "tr|A0A9J7GX47-1|A0A9J7GX47_CRIGR Computationally mapped isoform of Centrosomal protein of 170 kDa OS=Cricetulus griseus OX=10029 GN=Cep170 PE=3 SV=1 CANONICAL=A0A9J7G2T9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9/entry#A0A9J7GYA9-1", "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYEASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVDATTEVPHRATEALKSEEKSMDVSAMPRGTPLYGQPSWWGDDEVDEQRAFKSNGKPEEKNHETGTSGCSIDAKQAEEQSAAANEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHIAGAGHASFTIEFDDSMPGKVTIRDHVTKFTSDHRHKSKKATPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKTQSTEKHQDQAVTSSTHHRGGHGVPHGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKEGMSSSGSKRWVSQWASLAANHTRHDPEERLMGLSATVENETNTGEVGISLRSTSSAASLASQGERKRRTLPQLPNEEKPLENSRAKVVPQRSEIGEKQDTELQEKEAAAQVHQNEKRAAAKSLSQVDRPVNGEIPNTGGDNKALPPSGSSSSKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKLSSKSASGHIDKYREESSKQESQLVEKLSGHSTSKGERVIQNESKRRKAEEIPKSQTSKGDKKESSKPLVRQGSFTIEKPSSNIPIELIPHINKQNSSAPTSLALASASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDATKSGTREKIEKKAKSRSTDIGARADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRNPLTSADEHNIHSKLEGGKGTKSKTSPVASGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPIGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRTRANSISRLSDSKVKSVTSTHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSCDSRPQAAETPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHTSPGQTPALCPPETRALDPAAAAASAEFDNAESEADFSIHFNRFNPDGEEEDVVVHE", "length": 1536, "header": "tr|A0A9J7GYA9-1|A0A9J7GYA9_CRIGR Computationally mapped isoform of Centrosomal protein of 170 kDa OS=Cricetulus griseus OX=10029 GN=Cep170 PE=3 SV=1 CANONICAL=A0A9J7G2T9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZ39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9/entry#A0A9J7GZ39-1", "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYEASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVDATTEVPHRATEALKSEEKSMDVSAMPRGTPLYGQPSWWGDDEVDEQRAFKSNGKPEEKNHETGTSGCSIDAKQAEEQSAAANEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHIAGAGHASFTIEFDDSMPGKVTIRDHVTKFTSDHRHKSKKATPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKTQSTEKHQDQAVTSSTHHRGGHGVPHGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPIINEKHKGLVKDWALNSAAVVMEERKPFSTPGFHNSEEGMSSSGSKRWVSQWASLAANHTRHDPEERLMGLSATVENETNTGEVGISLRSTSSAASLASQGERKRRTLPQLPNEEKPLENSRAKVVPQRSEIGEKQDTELQEKEAAAQVHQNEKRAAAKSLSQVDRPVNGEIPNTGGDNKALPPSGSSSSKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKLSSKSASGHIDKYREESSKQESQLVEKLSGHSTSKGERVIQNESKRRKAEEIPKSQTSKGDKKESSKPLVRQGSFTIEKPSSNIPIELIPHINKQNSSAPTSLALASASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDATKSGTREKIEKKAKSRSTDIGARADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRNPLTSADEHNIHSKLEGGKGTKSKTSPVASGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPIGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRTRANSISRLSDSKVKSVTSTHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVFDESLNFRKIPPLVHSKTPEGNNGRSCDSRPQAAETPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHTSPGQTPALCPPETRALDPAAAAASAEFDNAESEADFSIHFNRFNPDGEEEDVVVHE", "length": 1576, "header": "tr|A0A9J7GZ39-1|A0A9J7GZ39_CRIGR Computationally mapped isoform of Centrosomal protein of 170 kDa OS=Cricetulus griseus OX=10029 GN=Cep170 PE=3 SV=1 CANONICAL=A0A9J7G2T9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2B5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9/entry#A0A9J7H2B5-1", "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYEASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVDATTEVPHRATEALKSEEKSMDVSAMPRGTPLYGQPSWWGDDEVDEQRAFKSNGKPEEKNHETGTSGCSIDAKQAEEQSAAANEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHIAGAGHASFTIEFDDSMPGKVTIRDHVTKFTSDHRHKSKKATPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKTQSTEKHQDQAVVFGVDDNQDYNRPIINEKHKGLVKDWALNSAAVVMEERKPFSTPGFHNSEEGMSSSGSKRWVSQWASLAANHTRHDPEERLMGLSATVENETNTGEVGISLRSTSSAASLASQGERKRRTLPQLPNEEKPLENSRAKVVPQRSEIGEKQDTELQEKEAAAQVHQNEKRAAAKSLSQVDRPVNGEIPNTGGDNKALPPSGSSSSKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKLSSKSASGHIDKYREESSKQESQLVEKLSGHSTSKGERVIQNESKRRKAEEIPKSQTSKGDKKESSKPLVRQGSFTIEKPSSNIPIELIPHINKQNSSAPTSLALASASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDATKSGTREKIEKKAKSRSTDIGARADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRNPLTSADEHNIHSKLEGGKGTKSKTSPVASGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPIGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRTRANSISRLSDSKVKSVTSTHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREELVDRVFDESLNFRKIPPLVHSKTPEGNNGRSCDSRPQAAETPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHTSPGQTPALCPPETRALDPAAAAASAEFDNAESEADFSIHFNRFNPDGEEEDVVVHE", "length": 1478, "header": "tr|A0A9J7H2B5-1|A0A9J7H2B5_CRIGR Computationally mapped isoform of Centrosomal protein of 170 kDa OS=Cricetulus griseus OX=10029 GN=Cep170 PE=3 SV=1 CANONICAL=A0A9J7G2T9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9/entry#A0A9J7JTG8-1", "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYEASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVDATTEVPHRATEALKSEEKSMDVSAMPRGTPLYGQPSWWGDDEVDEQRAFKSNGKPEEKNHETGTSGCSIDAKQAEEQSAAANEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHIAGAGHASFTIEFDDSMPGKVTIRDHVTKFTSDHRHKSKKATPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKTQSTEKHQDQAVTSSTHHRGGHGVPHGKLLKQKSEEPSVSIPFLQTALLRSSGSLGHRPSQEMDKMLKNQATSATSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPIINEKHKGLVKDWALNSAAVVMEERKPFSTPGFHNSEEGMSSSGSKRWVSQWASLAANHTRHDPEERLMGLSATVENETNTGEVGISLRSTSSAASLASQGERKRRTLPQLPNEEKPLENSRAKVVPQRSEIGEKQDTELQEKEAAAQVHQNEKRAAAKSLSQVDRPVNGEIPNTGGDNKALPPSGSSSSKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKLSSKSASGHIDKYREESSKQESQLVEKLSGHSTSKGERVIQNESKRRKAEEIPKSQTSKGDKKESSKPLVRQGSFTIEKPSSNIPIELIPHINKQNSSAPTSLALASASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDATKSGTREKIEKKAKSRSTDIGARADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRNPLTSADEHNIHSKLEGGKGTKSKTSPVASGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPIGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRTRANSISRLSDSKVKSVTSTHGSPSALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSCDSRPQAAETPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHTSPGQTPALCPPETRALDPAAAAASAEFDNAESEADFSIHFNRFNPDGEEEDVVVHE", "length": 1550, "header": "tr|A0A9J7JTG8-1|A0A9J7JTG8_CRIGR Computationally mapped isoform of Centrosomal protein of 170 kDa OS=Cricetulus griseus OX=10029 GN=Cep170 PE=3 SV=1 CANONICAL=A0A9J7G2T9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9/entry#A0A9J7K9M4-1", "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYEASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVDATTEVPHRATEALKSEEKSMDVSAMPRGTPLYGQPSWWGDDEVDEQRAFKSNGKPEEKNHETGTSGCSIDAKQAEEQSAAANEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHIAGAGHASFTIEFDDSMPGKVTIRDHVTKFTSDHRHKSKKATPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKTQSTEKHQDQAVVFGVDDNQDYNRPIINEKHKGLVKDWALNSAAVVMEERKPFSTPGFHNSEEGMSSSGSKRWVSQWASLAANHTRHDPEERLMGLSATVENETNTGEVGISLRSTSSAASLASQGERKRRTLPQLPNEEKPLENSRAKVVPQRSEIGEKQDTELQEKEAAAQVHQNEKRAAAKSLSQVDRPVNGEIPNTGGDNKALPPSGSSSSKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKLSSKSASGHIDKYREESSKQESQLVEKLSGHSTSKGERVIQNESKRRKAEEIPKSQTSKGDKKESSKPLVRQGSFTIEKPSSNIPIELIPHINKQNSSAPTSLALASASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDATKSGTREKIEKKAKSRSTDIGARADGRKFVQSSGRIRQPSVDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRNPLTSADEHNIHSKLEGGKGTKSKTSPVASGSSSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPIGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAIIRSGARLVPSDKFSPRTRANSISRLSDSKVKSVTSTHGSPSALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSCDSRPQAAETPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIESKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHTSPGQTPALCPPETRALDPAAAAASAEFDNAESEADFSIHFNRFNPDGEEEDVVVHE", "length": 1452, "header": "tr|A0A9J7K9M4-1|A0A9J7K9M4_CRIGR Computationally mapped isoform of Centrosomal protein of 170 kDa OS=Cricetulus griseus OX=10029 GN=Cep170 PE=3 SV=1 CANONICAL=A0A9J7G2T9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771665", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771665", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K315-1", "protein_name": "Centrosomal protein of 170 kDa", "gene_name": "Cep170", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTESKVEAAAEVPHRATEALKAEEKPVDVSAMPRGTPLYGQPSWWGDEEVDEQRAFKANGKPEGKSQEPATSGCSMEAKQLEEQSAAASEEALFPFCREPSYFEIPTKEFQPPSQIAESTIHEIPTKDTPSSHTAGAGHASFTIEFDDSTPGKVTIRDHVTKFASDQRHKSKKASPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERAEEDSKSIQSDAPVYLRRLKGNKHDDGTQSDSENAGVHRRCGKRAALEEHLRRHHSEQKKKIQSAEKHQDQAAVSQTAFMIAFFDEDHSRKRRSHSFTQSSGTLCQETTFSTPHTKLAKAESPPADAKVVSLSLQTSSTHHRGGHGVPHGKLLKQKSEEPSVSLPFLQTALLRSSGSLGHRPSQEMDIMLKNQATSASSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDFNRPIIKEKHKGLIKDWALNSAAVVMEERKPLSTPGFHNSEEAISSSGSKRWVSQWASLAANHTRHDPEERLMELSATRENETDTGEAGVSLRSTSCAASLASQGERKRRTLPQLPNEEKALENSRGKVVTPRSEIGEKQDTELQEKEAQGYQSEKHDADRGLSKMSRAVNGESPKTGGDSKALLHSGSNSSKEKSETDKETSLVKQTLAKIQQQEQKEQAQWTPTKFSSKNALGHIDKCREESSKQESQLGEKNSVHSTSKGERLVQNESKRRKAEEIPKSQTSKGDKKESSKSLVRQGSFTIDKPSSNIPIELIPHINKQNSSAPTALALTSASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGESERKSTQKRKSFTSLYKDRCSTSSPSKDVTKSGSREKIEKKTKSRSTDIGARADGRKFVQSSGRIRQPSIDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRTPLTSADEHSIHSKLEGGKAAKSKTSPVASGSASKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASSRTAEAVIRSGARLVPSDKLSPRTRANSISRLSDSKVKSMTSTHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSVDSRPQPPEHPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIENKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHSSPSQTPALCPAEARALHPAAAAAAAAASTEFENAESEADFSIHFNRFNPDGEEEDVTVHE", "length": 1650 }, "evidence": [ { "id": "A0A9J7G2T9", "url": "https://omabrowser.org/oma/group/A0A9J7G2T9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6A065-1", "protein_name": "Centrosomal protein of 170 kDa", "gene_name": "Cep170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASMDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVRGEMRVPEEALKHEKFTIQLQLSQKSSESELPKSASAKGTDSKVEAAAEVQPRATEALKSEEKPMDVSAMPRGTPLYGQPSWWGDAEEDEQRAFKANGKPEGKSQEAGASGCSTEAKHVEGQSAAASEEALFPFCREPSYFEIPTKEFQQPSQIAESTIHEIPTKDTPSSHTAGAGHASFTIEFDDSTPGKVTIRDHVTKFTSDQRHKSKKASPGTQDLPGIQTGMMAPENKVADWLAQNNPPQMVWERTEEDSKSIKSDVPVYLKRLKGNKHDDGTQSDSENAGAHRRCSKRATLEEHLRRHHSEQKKKAQSTEKHQEQAATSSTHHRGGHGVPHGKLLKQKSEEPSVSLPFLQTALLRSSGSLGHRPSQEMDVMLKNQATSASSEKDNDDDQSDKGTYTIELENPNSEEVEARKMIDKVFGVDDNQDYNRPIINEKHKGLIKDWALNSAAVVMEERKPLSTPGFHNSEEAISSSGSKRWVSQWASLAANHTRHDPEERLMELSATVENETDTGDAGVSLRSTSCTTSLASQGERKRRTLPQLPNEEKLLESSRAKVVPQRSEIGEKQDTELQEKEAQVYQSEKHDADRGLSKMSRAVNGESPKTGGDGKALLHSGSSSSKEKSETEKETSLVKQTLAKMQQQEQKEQAQWTPTKFPSKNALGHIDKCREESSKQESQLLEKVSGHSTSKGDRVIQNESKRRKAEEIPKCQASKGDKKESSKSLVRQGSFTIDKPSSNIPIELIPHINKQNSSVPTALALTSASRLRERSDSLDTDSSMDTTLILKDTEAVMAFLEAKLREDNNKTDEGPDTPSYNRDNSISPESDVDTASTISLVTGETERKSTQKRKSFTSLYKDRCSTSSPSKDVTKSGSREKIEKKAKSRSADIGARADGRKFVQSSGRIRQPSIDLTDDDQTSSVPHSAISDIMSSDQETYSCKSHGRTPLTSADEHNIHSKLEGGKATKSKTSPVASGSTSKSTTLPRPRPTRTSLLRRARLGEASDSELADADKASVASEVSTTSSTSKPPTGRRTISRIDLLAQPRRTRLGSLSARSDSEATISRSSASARTAEAVIRSGARLVPSDKLSPRTRANSISRLSDSKVKSMSSTHGSPSVNSRWRRFPTDYASTSEDEFGSNRNSPKHTRLRTSPALKTTRMQSTGSAMPASSSFKHRIKEQEDYIRDWTAHREEIARISQDLALIAREINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTREEVGDLHGEMHKLVDRVFDESLNFRKIPPLVHSKTPEGNNGRSVDSRPQPAEHPDHLTITRRRTWSRDEVMGDNLLLSSVFQFSRKIRQSIDKTAGKIRILFKDKDRNWDDIENKLRAESEVPIVKTSSMEISSILQELKRVEKQLQVINAMIDPDGTLEALNNMGFPNAILPSPPKQKSSPVNNHSSPSQTPALCPPETRALHPAAAGVAAAASTEFENAESEADFSIHFNRFNPDGEEEDVTVHE", "length": 1588 }, "evidence": [ { "id": "A0A9J7G2T9", "url": "https://omabrowser.org/oma/group/A0A9J7G2T9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2T9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T9" } ], "pmid": "" } ] } ] }, 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273162" } ] }, { "annotation": "Testis-specific spindle-associated factor that plays a role in spermatogenesis. 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Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2Y3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y3" } ], "pmid": "" }, { "name": "complement activation", "id": "GO:0006956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006956", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2Y3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "complement component C3b binding", "id": "GO:0001851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001851", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2Y3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G2Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y3" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 147, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 149, "end_pos": 151 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 223, "end_pos": 225 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G2Y7-1", "uniprot_ac": "A0A9J7G2Y7", "uniprot_id": "A0A9J7G2Y7_CRIGR", "mass": { "chemical_mass": 24315.0, "monoisotopic_mass": 24315.0 }, "refseq": { "ac": "XP_003500289", "name": "mucosal pentraxin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500289" }, "gene_names": [ { "name": "LOC100774861", "type": "recommended", "evidence": [ { "id": "A0A9J7G2Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y7" } ] }, { "name": "LOC100774861", "type": "synonym", "evidence": [ { "id": "XP_003500289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500289" } ] } ], "protein_names": [ { "name": "Pentraxin family member", "type": "recommended", "evidence": [ { "id": "A0A9J7G2Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y7/entry#names_and_taxonomy" } ] }, { "name": "mucosal pentraxin", "type": "synonym", "evidence": [ { "id": "XP_003500289", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500289" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613783.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003500289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500289" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2Y7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100774861", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y7", "locus": {} } ], "crossref": [ { "id": "A0A9J7G2Y7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G2Y7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774861", "url": "https://www.ncbi.nlm.nih.gov/gene/100774861", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774861", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774861", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G2Y7", "url": "https://www.orthodb.org/?gene=A0A9J7G2Y7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45869", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45869", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45869:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45869:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003500289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500289", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G2Y7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKLIVGALLLSVLLGCSFQEDMTGKAFVFPQESATAYVTLIPKMRKSLQNFTLCLKAFTDLTRPYSLFSYSTKTKHNEILLFVTKLGEYDIAVGNSEVIFKVPPNPYAPQHVCVSWESASGIVELWLDGKPMGRKGLKKGYSVGAEAKIIIGQEQDSFGGAFDAKQSFVGDIWEVSLWDHVVPLKEMDGGCYNGNLINWQALNFEDNGYVVTKPKLWA", "length": 219, "header": "tr|A0A9J7G2Y7-1|A0A9J7G2Y7_CRIGR Isoform 1 of Pentraxin family member OS=Cricetulus griseus OX=10029 GN=LOC100774861 PE=3 SV=1 CANONICAL=A0A9J7G2Y7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G2Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2Y7/entry#A0A9J7G2Y7-1", "sequence": { "sequence": "MTKLIVGALLLSVLLGCSFQEDMTGKAFVFPQESATAYVTLIPKMRKSLQNFTLCLKAFTDLTRPYSLFSYSTKTKHNEILLFVTKLGEYDIAVGNSEVIFKVPPNPYAPQHVCVSWESASGIVELWLDGKPMGRKGLKKGYSVGAEAKIIIGQEQDSFGGAFDAKQSFVGDIWEVSLWDHVVPLKEMDGGCYNGNLINWQALNFEDNGYVVTKPKLWA", "length": 219, "header": "tr|A0A9J7G2Y7-1|A0A9J7G2Y7_CRIGR Isoform 1 of Pentraxin family member OS=Cricetulus griseus OX=10029 GN=LOC100774861 PE=3 SV=1 CANONICAL=A0A9J7G2Y7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274930", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274930" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G324", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G324" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppp4r3a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G324", "locus": {} } ], "crossref": [ { "id": "A0A9J7G324", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G324", "database": "AlphaFoldDB", "categories": [] }, { "id": "100754152", "url": "https://www.ncbi.nlm.nih.gov/gene/100754152", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": 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"tr|A0A3L7HHD1-1|A0A3L7HHD1_CRIGR Computationally mapped isoform of SMEK homolog 1 OS=Cricetulus griseus OX=10029 GN=Ppp4r3a PE=3 SV=1 CANONICAL=A0A9J7G324-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G324-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G324/entry#A0A9J7G324-1", "sequence": { "sequence": "MTDTRRRVKVYTLNEDRQWDDRGTGHVSSGYVERLKGMSLLVRAESDGSLLLESKINPNTAYQKQQDTLIVWSEAENYDLALSFQEKAGCDEIWEKICQVQGKDPSVDITQDLVDESEEERFDDMSSPGLELPSCELSRLEEIAELVASSLPSPLRREKLALALENEGYIKKLLELFHVCEDLENIEGLHHLYEIIKGIFLLNRTALFEVMFSEECIMDVIGCLEYDPTLSQPRKHREFLTKTAKFKEVIPISDPELKQKIHQTYRVQYIQDMVLPTPSVFEENMLSTLHSFIFFNKVEIVGMLQEDEKFLTDLFAQLTDEATDEEKRQELVNFLKEFCAFSQTLQPQNRDAFFKTLSNMGILPALEVILGMDDTQVRSAATDIFSYLVEYNPSMVREFVMQEAQQNDDVSKKLTEQKITSKDILLINLIIEHMICDTDPELGGAVQLMGLLRTLVDPENMLATANKTEKTEFLGFFYKHCMHVLTAPLLANTTEDKPSKDDFQTAQLLALVLELLTFCVEHHTYHIKNYIINKDILRRVLVLMASKHAFLALCALRFKRKIIGLKDEFYNRYIMKSFLFEPVVKAFLNNGSRYNLMNSAIIEMFEFIRVEDIKSLTAHVIENYWKALEDVDYVQTFKGLKLRFEQQRERQDNPKLDSMRSILRNHRYRRDARTLEDEEEMWFNTDEDDMEDGEAVVSPSDKTKNDDDIMDPISKFMERKKLKESEEKEVLLKTNLSGRQSPSFKLSLSSGTKTNLSSQSSAASLPGSPGSPGSPGSPGSPGSVPKSTSQTAAITTKGGLVGLVDYPDDDEDDDEDEDKEDSLPLSKKAKFES", "length": 833, "header": "tr|A0A9J7G324-1|A0A9J7G324_CRIGR Isoform 1 of SMEK homolog 1 OS=Cricetulus griseus OX=10029 GN=Ppp4r3a PE=3 SV=1 CANONICAL=A0A9J7G324-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 277, "start_aa": "Thr", "end_pos": 277, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr277", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G324", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G324" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G324", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G324" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754152", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754152", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G324", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G324" } ], "pmid": "" }, { "name": "protein phosphatase 4 complex", "id": "GO:0030289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030289", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G324", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G324" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G324", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G324" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G324", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G324" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G324", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G324" } ], "pmid": "" }, { "name": "positive regulation of gluconeogenesis", "id": "GO:0045722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045722", "evidence": 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"length": 1177, "header": "tr|A0A9J7G327-1|A0A9J7G327_CRIGR Isoform 1 of Liprin-alpha-4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ppfia4 PE=3 SV=1 CANONICAL=A0A9J7G327-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027273362.1. 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[ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751054", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751054", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G338", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G338-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G338-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGKATSEASVSSPEETEPEPAKVPTTEASGEVAASESTGQEQAPEPQKPGSQALDHVAPEASATPATTKPEPPSEDVPSAPLQLTLEDVSHSSLTVSWEPPEKLGKLGLQGYVLELCREGASEWVPVNPRPVMVTQQTVRNLALGDKFFLRVTAVSSAGAGPAAVLDHPVHIQEIIEAPKIRVPRHLRQTYIRQVGESVNLQIPFQGKPKPQASWTHNGHALDSQRVNVRTGDQDSILFIRSAQRSDSGRYELTVHLEGLEAKANIDILVIEKPGPPSSIRLLDVWGCNAALEWTPPQDTGNTELLGYTVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSDQATTTKELAHIQKADITAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMDIQGDPKYRAVSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKVLKDLVEVQGCVNKENVREDP", "length": 501, "header": "tr|A0A9J7G338-1|A0A9J7G338_CRIGR Isoform 1 of Myosin-binding protein H OS=Cricetulus griseus OX=10029 GN=Mybph PE=3 SV=1 CANONICAL=A0A9J7G338-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G338-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G338/entry#A0A9J7G338-1", "sequence": { "sequence": "MTGKATSEASVSSPEETEPEPAKVPTTEASGEVAASESTGQEQAPEPQKPGSQALDHVAPEASATPATTKPEPPSEDVPSAPLQLTLEDVSHSSLTVSWEPPEKLGKLGLQGYVLELCREGASEWVPVNPRPVMVTQQTVRNLALGDKFFLRVTAVSSAGAGPAAVLDHPVHIQEIIEAPKIRVPRHLRQTYIRQVGESVNLQIPFQGKPKPQASWTHNGHALDSQRVNVRTGDQDSILFIRSAQRSDSGRYELTVHLEGLEAKANIDILVIEKPGPPSSIRLLDVWGCNAALEWTPPQDTGNTELLGYTVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSDQATTTKELAHIQKADITAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMDIQGDPKYRAVSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKVLKDLVEVQGCVNKENVREDP", "length": 501, "header": "tr|A0A9J7G338-1|A0A9J7G338_CRIGR Isoform 1 of Myosin-binding protein H OS=Cricetulus griseus OX=10029 GN=Mybph PE=3 SV=1 CANONICAL=A0A9J7G338-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 65, "start_aa": "Thr", "end_pos": 65, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr65", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G338", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G338" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751054", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751054", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G338", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G338" } ], "pmid": "" }, { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G338", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G338" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G338", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G338" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G338", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G338" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G338", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G338" }, { "id": "PS50853", "database": 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Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614753.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509740" } ] }, { "annotation": "D-glutamate cyclase that converts D-glutamate to 5-oxo-D-proline.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G353", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353#function" }, { "database": "UniProtKB", "id": "ARBA00056433", "url": "https://www.uniprot.org/uniprotkb/ARBA00056433#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G353", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dglucy", "url": 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"https://www.genome.jp/dbget-bin/www_bget?cge:100753550", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIGHPGL", "url": "https://omabrowser.org/oma/group/HIGHPGL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G353", "url": "https://www.orthodb.org/?gene=A0A9J7G353", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32022", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32022", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32022:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32022:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07286", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07286", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509740", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "22360", "url": "https://www.rhea-db.org/rhea/22360", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G353", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G353-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPFSLLLRSHLPSAIRSLPKAAHIRNTSSMTEGLQPASVVVLPRSLAPDFESFCQANRGPLPLLGRCEPEKVLPRLSTVPDIRAICPQFQKYEFGALTGILASLEEYSEQLEDMVIFTIDCSFSIEEALEQAGISRRDPAGPSHAGAYKTTVPCAAIAGFCCPLVATMRPIPKDKLERLLQVTHSLGGQQGQPIHIGDPELLGIKALSKPDYGNYVECEPEDVPVFWPSQLTGLEAVSSCKAPLAFSSTPGCTVMILKDTVSPASCLIPEMVPEVHAISKDPLHYSIVSAAAVQKIRKLESIIGIDPGNRGIGHLLGKDELLRAALSLSHAHSVLVTTGFPTHFNHEPPEETDGPPGAIALAAFLQALGKETSMVVDQRALNLHTKLVEDAVKQGVLKTPIPLLTYQGKSVEDAQAFLCKDGDPKSPRFDHLVAIERAGRAADGNYYNARKMNIKHLVDPIDDIFLAAQKIPGISSTGVGDGGNELGMGTVKEAVKKYIRNGEVIACDVEADFAVIAGVSNWGGYALACALYILNSCDIHERYLRRAVGPSRVAVEQSWTQALPSVAKEEKMLGILVQNQVRSGVSGIVGMEVDGLPFYGVHDEMVQKLLDVTAGHL", "length": 618, "header": "tr|A0A9J7G353-1|A0A9J7G353_CRIGR Isoform 1 of D-glutamate cyclase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Dglucy PE=3 SV=1 CANONICAL=A0A9J7G353-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G353-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353/entry#A0A9J7G353-1", "sequence": { "sequence": "MVPFSLLLRSHLPSAIRSLPKAAHIRNTSSMTEGLQPASVVVLPRSLAPDFESFCQANRGPLPLLGRCEPEKVLPRLSTVPDIRAICPQFQKYEFGALTGILASLEEYSEQLEDMVIFTIDCSFSIEEALEQAGISRRDPAGPSHAGAYKTTVPCAAIAGFCCPLVATMRPIPKDKLERLLQVTHSLGGQQGQPIHIGDPELLGIKALSKPDYGNYVECEPEDVPVFWPSQLTGLEAVSSCKAPLAFSSTPGCTVMILKDTVSPASCLIPEMVPEVHAISKDPLHYSIVSAAAVQKIRKLESIIGIDPGNRGIGHLLGKDELLRAALSLSHAHSVLVTTGFPTHFNHEPPEETDGPPGAIALAAFLQALGKETSMVVDQRALNLHTKLVEDAVKQGVLKTPIPLLTYQGKSVEDAQAFLCKDGDPKSPRFDHLVAIERAGRAADGNYYNARKMNIKHLVDPIDDIFLAAQKIPGISSTGVGDGGNELGMGTVKEAVKKYIRNGEVIACDVEADFAVIAGVSNWGGYALACALYILNSCDIHERYLRRAVGPSRVAVEQSWTQALPSVAKEEKMLGILVQNQVRSGVSGIVGMEVDGLPFYGVHDEMVQKLLDVTAGHL", "length": 618, "header": "tr|A0A9J7G353-1|A0A9J7G353_CRIGR Isoform 1 of D-glutamate cyclase, mitochondrial OS=Cricetulus griseus OX=10029 GN=Dglucy PE=3 SV=1 CANONICAL=A0A9J7G353-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G353", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G353", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753550", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753550", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IQ88-1", "protein_name": "D-glutamate cyclase, mitochondrial", "gene_name": "dglucy", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLLKCARVTNFLQRAVGTKGLTYSTRARKKPGFQQANVVILHKDLADDFEAFCRANSSPLPLLYRSKCGEWSAGPLATASDIREDCPEYCVFENGRLMKKVSSLSSFTSELEHMVTFYLGCSFGFESALTAAGVPVRNVEQGRNVSMYKTSVPCIKAGQIHCPMVVTMRPVPEDKLDATAQCTHAIPLAHGGPVHIGDPKLLGIRDLSRPDYGDPVDARPADVPVFWACGVTGVEAVKSCKSALAFTHSPGCMFITDQKAEAISPLSLEPAQRPLTFRISQDPQHYSMASERAVQQIRAIEELAVEDPGSRGIRALFLQDELLKACLSLSHSSSVLITTGFPTHYMHNPPEETDGPPGALAMAAMLQALHKEVVIVTDQRALEMNQHIMQDAVEKGVIKSAVPVISFQSNGPDSALHFLCGDGDPTKPRFDHLVAIERSGRAADGNYYNMRGVNIKHLLDPIDELFTAASTIAGITTTGIGDGGNELGMGKVKAAVKAHMPNGKLIACDVAADFAITAGVSNWGGYAVACALYVLNLCPVHQRYLQRGLGLSPTPEQQSKWAECLPTVAKEEEMLRILVKYGVRSGKTANLGLEVDGLTFHPYHSDIIQRLRHLTYD", "length": 618 }, "evidence": [ { "id": "A0A9J7G353", "url": "https://omabrowser.org/oma/group/A0A9J7G353/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A9W3-1", "protein_name": "D-glutamate cyclase, mitochondrial", "gene_name": "Dglucy", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MENTQVLCGSFWDGMVPFSLLLRSCLPSAIRSLPKAAHIRNISSMTGGLQPASVVVLPRSLAPAFESFCQGNHGPLPLLGQSEPEKTFPQLSAVPDIRTICPQFQKYEFGTCTGILTSLEEYSEQLKDMVTFIMDCSFSIEEALEQAGIPRRDLTGSGHAGAYKTAVPCATIAGFCCPLVVTMRPVPKDKLERLLLATHSLGGQQGQPIHIGDPELLGIKPLSKPDYGSYVECRPGDVPVFWPSHLTSLEAVIGCKAPLAFASPPGCTVMIPRDTVSPASRPTPQMVPEVHAISKDPLHYSIVSAPAAQKIRELESTIATDPGNRGIGHLLLKDELLLAALSLSHAHSVLVTTGFPTHFSHEPPEETDGPPGAIALAAFLQALGKEAAMVVDRRALNLHTKIVEDAVKQGVLKTPIPILTYRGGSVEDARAFLCKDGDPKSPRFDHLVAVERAGRAADGNYYNARKVNIKHLVDPIDDIFLAAQKIPGISSTGVGDGGNELGMGRVKEAVKKHIRNGDVIACDVEADFAVIAGVSNWGGYALACALYILNSCPVHERYLRRATGPSGEAGEQSWIQALPSVAKEEKMLGILVQNQVRSGVSGIVGMEVDGLPFHGVHAEMIQKLVDVTTVPM", "length": 632 }, "evidence": [ { "id": "A0A9J7G353", "url": "https://omabrowser.org/oma/group/A0A9J7G353/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z3D6-1", "protein_name": "D-glutamate cyclase, mitochondrial", "gene_name": "DGLUCY", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFTLHLRSRLPSAIRSLILQKKPNIRNTSSMAGELRPASLVVLPRSLAPAFERFCQVNTGPLPLLGQSEPEKWMLPPQGAISETRMGHPQFWKYEFGACTGSLASLEQYSEQLKDMVAFFLGCSFSLEEALEKAGLPRRDPAGHSQTTVPCVTHAGFCCPLVVTMRPIPKDKLEGLVRACCSLGGEQGQPVHMGDPELLGIKELSKPAYGDAMVCPPGEVPVFWPSPLTSLGAVSSCETPLAFASIPGCTVMTDLKDAKAPPGCLTPERIPEVHHISQDPLHYSIASVSASQKIRELESMIGIDPGNRGIGHLLCKDELLKASLSLSHARSVLITTGFPTHFNHEPPEETDGPPGAVALVAFLQALEKEVAIIVDQRAWNLHQKIVEDAVEQGVLKTQIPILTYQGGSVEAAQAFLCKNGDPQTPRFDHLVAIERAGRAADGNYYNARKMNIKHLVDPIDDLFLAAKKIPGISSTGVGDGGNELGMGKVKEAVRRHIRHGDVIACDVEADFAVIAGVSNWGGYALACALYILYSCAVHSQYLRKAVGPSRAPGDQAWTQALPSVIKEEKMLGILVQHKVRSGVSGIVGMEVDGLPFHNTHAEMIQKLVDVTTAQV", "length": 616 }, "evidence": [ { "id": "A0A9J7G353", "url": "https://omabrowser.org/oma/group/A0A9J7G353/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BH86-1", "protein_name": "D-glutamate cyclase, mitochondrial", "gene_name": "Dglucy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTISFLLRSCLRSAVRSLPKAALIRNTSSMTEGLQPASVVVLPRSLAPAFESFCQGNRGPLPLLGQSEAVKTLPQLSAVSDIRTICPQLQKYKFGTCTGILTSLEEHSEQLKEMVTFIIDCSFSIEEALEQAGIPRRDLTGPSHAGAYKTTVPCATIAGFCCPLVVTMRPIPKDKLERLLQATHAIRGQQGQPIHIGDPGLLGIEALSKPDYGSYVECRPEDVPVFWPSPLTSLEAVISCKAPLAFASPPGCMVMVPKDTASSASCLTPEMVPEVHAISKDPLHYSIVSAPAAQKVRELESTIAVDPGNRGIGHLLLKDELLQAALSLSHARSVLVTTGFPTHFNHEPPEETDGPPGAIALAAFLQALGKETAMVVDQRALNLHMRIVEDAIRQGVLKTPIPILTYQGRSMEDARAFLCKDGDPKSPRFDHLVAIERAGRAADGNYYNARKMNIKHLVDPIDDIFLAAQKIPGISSTGVGDGGNELGMGKVKAAVKKHIRNGDVIACDVEADFAVIAGVSNWGGYALACALYILNSCQVHERYLRRATGPSRRAGEQSWIQALPSVAKEEKMLGILVENQVRSGVSGIVGMEVDGLPFHDVHAEMIRKLVGATTVHM", "length": 617 }, "evidence": [ { "id": "A0A9J7G353", "url": "https://omabrowser.org/oma/group/A0A9J7G353/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "D-glutamate cyclase activity", "id": "GO:0047820", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047820", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G353", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G353", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glutamate metabolic process", "id": "GO:0006536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006536", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G353", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "22360", "name": "", "equation": "D-glutamate = 5-oxo-D-proline + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7G353-1" ], "evidence": [ { "id": "22360", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/22360" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7G353", "gene_name": "Dglucy", "activity": [ { "ec_number": "4.2.1.48", "activity": "D-glutamate = 5-oxo-D-proline + H2O.", "evidence": [ { "id": "A0A9J7G353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353" } ] }, { "ec_number": "4.2.1.48", "activity": "", "evidence": [ { "id": "A0A9J7G353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G353", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G353" }, { "id": "PF14336", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14336" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "D-glutamate cyclase-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 300, "end_pos": 610, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.1.48", "ec_name": "D-glutamate = 5-oxo-D-proline + H2O.", "evidence": [ { "id": "4.2.1.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.48" }, { "id": "4.2.1.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.48" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 250 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G398-1", "uniprot_ac": "A0A9J7G398", "uniprot_id": "A0A9J7G398_CRIGR", "mass": { "chemical_mass": 56673.0, "monoisotopic_mass": 56673.0 }, "refseq": { "ac": "XP_027275063", "name": "megakaryocyte-associated tyrosine-protein kinase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275063" }, "gene_names": [ { "name": "Matk", "type": "recommended", "evidence": [ { "id": "A0A9J7G398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398" } ] }, { "name": "Matk", "type": "synonym", "evidence": [ { "id": "XP_027275063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275063" } ] } ], "protein_names": [ { "name": "Tyrosine-protein kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7G398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.2", "type": "synonym", "evidence": [ { "id": "A0A9J7G398", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398/entry#names_and_taxonomy" } ] }, { "name": "megakaryocyte-associated tyrosine-protein kinase", "type": "synonym", "evidence": [ { "id": "XP_027275063", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275063" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027275063.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275063", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275063" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G398", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Matk", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398", "locus": {} } ], "crossref": [ { "id": "A0A9J7G398", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G398", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09937", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09937", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764076", "url": "https://www.ncbi.nlm.nih.gov/gene/100764076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764076", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G398", "url": "https://www.orthodb.org/?gene=A0A9J7G398", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275063", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275063", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G398", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G398-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGRGRGRDSGVSWLAFDGWESKDLPRVSPRFLRAWHPSPAAARMPTRRWAPGTQCMTKCENSRPKPGELAFRKGDMVTILEACEDKSWYRAKHHSSGQEGLLAAAALRQREALSTDPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVCFCNLMDMVEHYTKDKGAICTKLVKPKRKQGTKSAEEELAKAGWLLNLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKLQHRNLVRLLGVILHHGLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFSLHVAEGMEYLESKKLVHRDLAARNILISEDLVAKVSDFGLAKAERKGLDSSRLPVKWSAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPDGCPGPVHTLMGSCWEAEPARRPPFRKIAEKLGRELRSAGATAPLGGQEAEGSALPRSQEP", "length": 510, "header": "tr|A0A9J7G398-1|A0A9J7G398_CRIGR Isoform 1 of Tyrosine-protein kinase OS=Cricetulus griseus OX=10029 GN=Matk PE=3 SV=1 CANONICAL=A0A9J7G398-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G398-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398/entry#A0A9J7G398-1", "sequence": { "sequence": "MAGRGRGRDSGVSWLAFDGWESKDLPRVSPRFLRAWHPSPAAARMPTRRWAPGTQCMTKCENSRPKPGELAFRKGDMVTILEACEDKSWYRAKHHSSGQEGLLAAAALRQREALSTDPKLSLMPWFHGKISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTIDEAVCFCNLMDMVEHYTKDKGAICTKLVKPKRKQGTKSAEEELAKAGWLLNLQHLTLGAQIGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKLQHRNLVRLLGVILHHGLYIVMEHVSKGNLVNFLRTRGRALVSTSQLLQFSLHVAEGMEYLESKKLVHRDLAARNILISEDLVAKVSDFGLAKAERKGLDSSRLPVKWSAPEALKNGRFSSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPDGCPGPVHTLMGSCWEAEPARRPPFRKIAEKLGRELRSAGATAPLGGQEAEGSALPRSQEP", "length": 510, "header": "tr|A0A9J7G398-1|A0A9J7G398_CRIGR Isoform 1 of Tyrosine-protein kinase OS=Cricetulus griseus OX=10029 GN=Matk PE=3 SV=1 CANONICAL=A0A9J7G398-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G398", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G398", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764076", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764076", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G398", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G398", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G398", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G398", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G398" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3HE98-1", "Q63980-1", "G3HAZ9-1", "G3IFY3-1", "G3GY19-1", "G3GYQ3-1", "G3H552-1", "G3HQK4-1", "G3HQP4-1", "G3HVB0-1", "G3IG17-1", "A0A9J7GY37-1", "G3H0L5-1", "G3GVI7-1", "G3HGZ0-1", "G3HGZ1-1", "G3HY52-1", "G3HEH4-1", "A0A9J7FB39-1", "G3IIC0-1", "A0A8C2QBZ6-1", "A0A9J7EY99-1", "A0A9J7FT87-1", "A0A9J7G180-1", "A0A8C2MTI7-1", "A0A8C2N3H2-1", "A0A9J7K5K0-1", "A0A8C2LY52-1", "A0A8C2MDG3-1", "A0A8C2QJN6-1", "A0A8C2MCF8-1", "A0A8C2MPY4-1", "A0A8C2QMK6-1", "A0A8C2N9X1-1", "A0A9J7KFV4-1", "A0A9J7EUZ9-1", "A0A9J7F492-1", "A0A8C2LIN5-1", "A0A9J7F1W8-1", "A0A9J7F4U9-1", "A0A9J7FIT0-1", "A0A9J7FX84-1", "A0A8C2MH43-1", "A0A9J7G9F9-1", "A0A9J7GHS8-1", "A0A9J7GVQ2-1", "A0A8C2MAM4-1", "A0A9J7H847-1", "A0A9J7H9K9-1", "A0A9J7HE43-1", "A0A061I765-1", "A0A061IKX8-1", "A0A8C2M5A7-1", "A0A9J7K378-1", "A0A8C2MJB3-1", "A0A9J7F773-1", "A0A8C2LKN1-1", "A0A9J7JQV6-1", "A0A9J7K3R5-1", "A0A9J7K8D7-1", "A0A9J7KAA7-1", "A0A8C2MV78-1", "A0A8C2N756-1", "A0A9J7KBU9-1", "A0A8C2QPB0-1", "A0A9J7F6S3-1", "A0A9J7FEZ2-1", "A0A9J7FS53-1", "A0A9J7FUX7-1", "A0A9J7FZG2-1", "A0A9J7FZH7-1", "A0A9J7G654-1", "A0A8C2QLE7-1", "A0A9J7GBI2-1", "A0A9J7GHB3-1", "A0A9J7GIN7-1", "A0A9J7GJW5-1", "A0A9J7GMF3-1", "A0A9J7GSH6-1", "A0A8C2MTN3-1", "A0A9J7JZS0-1", "A0A8C2M187-1", "A0A9J7GT89-1", "A0A9J7GVJ0-1", "A0A9J7GYA4-1", "A0A9J7H167-1", "A0A9J7H923-1", "A0A9J7JLX1-1", "A0A8C2LP31-1", "A0A8C2QHC0-1", "A0A8C2LWB2-1", "A0A9J7G398-1", "A0A8C2N659-1", "A0A9J7JTY4-1", "A0A9J7GP54-1", "A0A9J7K499-1", "A0A9J7HEE3-1", "A0A061IJA8-1", "A0A061IR93-1", "A0A8C2LLJ5-1", "A0A8C2M0D7-1", "A0A8C2M0T0-1", "A0A8C2M8I7-1", "A0A8C2N2G1-1", "A0A8C2N2R2-1", "A0A9J7G2Q4-1", "A0A8C2LHA9-1", "A0A8C2M4P9-1", "A0A9J7F8T9-1", "A0A9J7GLP2-1", "A0A9J7GRN1-1", "A0A3L7HKL8-1", "A0A8C2L7Q1-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061I765", "gene_name": "Wee1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I765", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I765" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061I765", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I765" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IKX8", "gene_name": "Epha7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IKX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IKX8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A061IKX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IKX8" } ] } ] }, { "uniprot_ac": "A0A061IR93", "gene_name": "Kdr", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IR93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IR93" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A061IR93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IR93" } ] } ] }, { "uniprot_ac": "A0A3L7HKL8", "gene_name": "Pkdcc", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKL8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7HKL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKL8" } ] } ] }, { "uniprot_ac": "A0A8C2L7Q1", "gene_name": "Alk", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7Q1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8C2L7Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7Q1" } ] } ] }, { "uniprot_ac": "A0A8C2LHA9", "gene_name": "Fgfr4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHA9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8C2LHA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHA9" } ] } ] }, { "uniprot_ac": "A0A8C2LIN5", "gene_name": "Ntrk1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIN5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8C2LIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIN5" } ] } ] }, { "uniprot_ac": "A0A8C2LKN1", "gene_name": "Wee2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKN1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2LKN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKN1" } ] } ] }, { "uniprot_ac": "A0A8C2LLJ5", "gene_name": "Jak1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LLJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLJ5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2LLJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLJ5" } ] } ] }, { "uniprot_ac": "A0A8C2LP31", "gene_name": "Epha5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LP31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP31" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8C2LP31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP31" } ] } ] }, { "uniprot_ac": "A0A8C2LWB2", "gene_name": "Frk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LWB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWB2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2LWB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWB2" } ] } ] }, { 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"id": "A0A9J7F6S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6S3" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": 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O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G2Q4", "gene_name": "Abl2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ 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{ "id": "A0A9J7GHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHS8" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": 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"ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GP54", "gene_name": "Lck", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP54" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GP54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP54" } ] } ] }, { "uniprot_ac": "A0A9J7GRN1", "gene_name": "Ntrk2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRN1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7GRN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRN1" } ] } ] }, { "uniprot_ac": "A0A9J7GSH6", "gene_name": "Lyn", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GSH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GSH6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GSH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GSH6" } ] } ] }, { "uniprot_ac": "A0A9J7GT89", "gene_name": "LOC100774420", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A9J7GVQ2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7GVQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVQ2" } ] } ] }, { "uniprot_ac": "A0A9J7GY37", "gene_name": "Src", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY37" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GY37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY37" } ] } ] }, { "uniprot_ac": "A0A9J7GYA4", "gene_name": "Ephb1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GYA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYA4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7GYA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYA4" } ] } ] }, { "uniprot_ac": "A0A9J7H167", "gene_name": "Epha3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H167", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H167" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7H167", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H167" } ] } ] }, { "uniprot_ac": "A0A9J7H847", "gene_name": "Jak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H847", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H847" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7H847", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H847" } ] } ] }, { "uniprot_ac": "A0A9J7H923", "gene_name": "Bmx", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H923" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7H923", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H923" } ] } ] }, { "uniprot_ac": "A0A9J7H9K9", "gene_name": "Erbb3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9K9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7H9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9K9" } ] } ] }, { "uniprot_ac": "A0A9J7HE43", "gene_name": "Egfr", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HE43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE43" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7HE43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HE43" } ] } ] }, { "uniprot_ac": "A0A9J7HEE3", "gene_name": "LOC100774072", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HEE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7HEE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEE3" } ] } ] }, { "uniprot_ac": "A0A9J7JLX1", "gene_name": "Tyro3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLX1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7JLX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLX1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JTY4", "gene_name": "Fgr", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTY4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JTY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTY4" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K378", "gene_name": "Musk", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K378" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7K378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K378" } ] } ] }, { "uniprot_ac": "A0A9J7K3R5", "gene_name": "LOC100760475", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3R5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7K3R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3R5" } ] } ] }, { "uniprot_ac": "A0A9J7K499", "gene_name": "Flt1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K499", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K499" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7K499", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K499" } ] } ] }, { "uniprot_ac": "A0A9J7K5K0", "gene_name": "Ptk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K5K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5K0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7K5K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5K0" } ] } ] }, { "uniprot_ac": "A0A9J7K8D7", "gene_name": "Flt3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8D7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7K8D7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8D7" } ] } ] }, { "uniprot_ac": "A0A9J7KAA7", "gene_name": "Flt4", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KAA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAA7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A9J7KAA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAA7" } ] } ] }, { "uniprot_ac": "A0A9J7KBU9", "gene_name": "Itk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KBU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBU9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7KBU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBU9" } ] } ] }, { "uniprot_ac": "A0A9J7KFV4", "gene_name": "LOC100767740", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7KFV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV4" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H0L5", "gene_name": "Blk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H0L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H0L5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3H0L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H0L5" } ] } ] }, { "uniprot_ac": "G3H552", "gene_name": "Fer", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H552", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H552" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3H552", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H552" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HE98", "gene_name": "Hck", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HE98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HE98" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3HE98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HE98" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ 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{ "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "G3HGZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HGZ1" } ] } ] }, { "uniprot_ac": "G3HQK4", "gene_name": "Ddr2", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HQK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HQK4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "G3HQK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HQK4" } ] } ] }, { "uniprot_ac": "G3HQP4", "gene_name": "Ddr1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HQP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HQP4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "G3HQP4", "database": "UniProtKB", 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"protein_names": [ { "name": "Major facilitator superfamily domain-containing protein 12", "type": "recommended", "evidence": [ { "id": "A0A9J7G3A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A1/entry#names_and_taxonomy" } ] }, { "name": "major facilitator superfamily domain-containing protein 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007645153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645153" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 339 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614244.1) and transcript sequence (IACG01043541.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007645153.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645153" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3A1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mfsd12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A1", "locus": {} } ], "crossref": [ { "id": "A0A9J7G3A1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G3A1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17491", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17491", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771307", "url": "https://www.ncbi.nlm.nih.gov/gene/100771307", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771307", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771307", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G3A1", "url": "https://www.orthodb.org/?gene=A0A9J7G3A1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11328:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11328:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645153", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29655", "url": "https://www.rhea-db.org/rhea/29655", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G3A1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPPPGGAGPGPPRTLSPAARLSFAVGHFLNDLCAGMWFTYLLLFLHSVRGYSSRGAGLLLLLGQAADGLCTPLVGYEADRAACARCGPRKAWHLAGTVCVLLSFPFIFSPCLGCGEATPEWAALLYYGPFIVIFQFGWAATQIAHLSLIPELVTSDHEKVELTALRYAFTVVANITVYGAAWLLLHLQGSSHAGQDISVGDQLGVQDVPVFRNLALMVVGVGAIFSLLFHLGTKEGRRPCPREMEPDEHSPLVAPTARPLLLWKHWLREPAFYQVGMLYMTTRLIVNLSQTYIAMYLTYSLSLPKKFIATIPLVMYLSGFLSSFLMKPVNRRIGRNMTYFSGLLVILAFAAWVALVDKLGVAVYGAAVLLGAGCATVLVTSLAMTADLIGPHTHSGAFVYGAMSFSDKVANGLAVMAVQSLHPCPSELCCRACVGFYHWVMVTVTGGVGVAAALALCSLLIWPIRIRTRTGDPRDRP", "length": 478, "header": "tr|A0A9J7G3A1-1|A0A9J7G3A1_CRIGR Isoform 1 of Major facilitator superfamily domain-containing protein 12 OS=Cricetulus griseus OX=10029 GN=Mfsd12 PE=3 SV=1 CANONICAL=A0A9J7G3A1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G3A1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A1/entry#A0A9J7G3A1-1", "sequence": { "sequence": "MSPPPGGAGPGPPRTLSPAARLSFAVGHFLNDLCAGMWFTYLLLFLHSVRGYSSRGAGLLLLLGQAADGLCTPLVGYEADRAACARCGPRKAWHLAGTVCVLLSFPFIFSPCLGCGEATPEWAALLYYGPFIVIFQFGWAATQIAHLSLIPELVTSDHEKVELTALRYAFTVVANITVYGAAWLLLHLQGSSHAGQDISVGDQLGVQDVPVFRNLALMVVGVGAIFSLLFHLGTKEGRRPCPREMEPDEHSPLVAPTARPLLLWKHWLREPAFYQVGMLYMTTRLIVNLSQTYIAMYLTYSLSLPKKFIATIPLVMYLSGFLSSFLMKPVNRRIGRNMTYFSGLLVILAFAAWVALVDKLGVAVYGAAVLLGAGCATVLVTSLAMTADLIGPHTHSGAFVYGAMSFSDKVANGLAVMAVQSLHPCPSELCCRACVGFYHWVMVTVTGGVGVAAALALCSLLIWPIRIRTRTGDPRDRP", "length": 478, "header": "tr|A0A9J7G3A1-1|A0A9J7G3A1_CRIGR Isoform 1 of Major facilitator superfamily domain-containing protein 12 OS=Cricetulus griseus OX=10029 GN=Mfsd12 PE=3 SV=1 CANONICAL=A0A9J7G3A1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3A1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774111", "url": "https://www.ncbi.nlm.nih.gov/gene/100774111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042917", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042917", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774111", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774111", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G679", "url": "https://www.orthodb.org/?gene=A0A9J7G679", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47656:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47656:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027274860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LZM1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LZM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G679", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G679-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAGSQQLQFAEGAVFPSFPAAHPGGPPLPPHAPPDSRAPAVTPCFSGRSPGPAAQTPAGLDPPRAPKGAAAPSAPPQRRKRTSFSSEQLQLLELVFRQTMYPDIQLRERLASLTLLPESRIQVTVRCFPPVSQVWFQNRRAKSRRQSGKWFQPLSARREAWLHRSAPGTEARCLKPQPPLQADVNCLPDPNRAGGGVCDSGSQGQSFDTYPPLSEDFGSKLDSWEEHIFSAFGNF", "length": 237, "header": "tr|A0A9J7G679-1|A0A9J7G679_CRIGR Isoform 1 of Homeobox protein MIXL1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mixl1 PE=4 SV=1 CANONICAL=A0A9J7G679-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LZM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679/entry#A0A8C2LZM1-1", "sequence": { "sequence": "MAAAGSQQLQFAEGAVFPSFPAAHPGGPPLPPHAPPDSRAPAVTPCFSGRSPGPAAQTPAGLDPPRAPKGAAAPSAPPQRRKRTSFSSEQLQLLELVFRQTMYPDIQLRERLASLTLLPESRIQVWFQNRRAKSRRQSGKWFQPLSARREAWLHRSAPGTEARCLKPQPPLQADVNCLPDPNRAGGGVCDSGSQGQSFDTYPPLSEDFGSKLDSWEEHIFSAFGNF", "length": 226, "header": "tr|A0A8C2LZM1-1|A0A9J7G679_CRIGR Computationally mapped isoform of Homeobox protein MIXL1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mixl1 PE=4 SV=1 CANONICAL=A0A9J7G679-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G679-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679/entry#A0A9J7G679-1", "sequence": { "sequence": "MAAAGSQQLQFAEGAVFPSFPAAHPGGPPLPPHAPPDSRAPAVTPCFSGRSPGPAAQTPAGLDPPRAPKGAAAPSAPPQRRKRTSFSSEQLQLLELVFRQTMYPDIQLRERLASLTLLPESRIQVTVRCFPPVSQVWFQNRRAKSRRQSGKWFQPLSARREAWLHRSAPGTEARCLKPQPPLQADVNCLPDPNRAGGGVCDSGSQGQSFDTYPPLSEDFGSKLDSWEEHIFSAFGNF", "length": 237, "header": "tr|A0A9J7G679-1|A0A9J7G679_CRIGR Isoform 1 of Homeobox protein MIXL1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mixl1 PE=4 SV=1 CANONICAL=A0A9J7G679-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 44, "start_aa": "Thr", "end_pos": 44, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr44", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LZM1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZM1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LZM1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZM1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774111", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G679", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G679", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G679", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G679", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679" } ], "pmid": "" }, { "name": "hematopoietic progenitor cell differentiation", "id": "GO:0002244", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G679", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679" } ], "pmid": "" }, { "name": "negative regulation of hematopoietic progenitor cell differentiation", "id": "GO:1901533", "url": 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"name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G679", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G679", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679" } ], "pmid": "" }, { "name": "RNA polymerase II-specific DNA-binding transcription factor binding", "id": "GO:0061629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G679", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G679" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], 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{ "id": "A0A9J7G4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ] }, { "name": "Jdp2", "type": "synonym", "evidence": [ { "id": "XP_016831256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831256" } ] } ], "protein_names": [ { "name": "Protein c-Fos", "type": "recommended", "evidence": [ { "id": "A0A9J7G4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7/entry#names_and_taxonomy" } ] }, { "name": "Cellular oncogene fos", "type": "synonym", "evidence": [ { "id": "A0A9J7G4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7/entry#names_and_taxonomy" } ] }, { "name": "Transcription factor AP-1 subunit c-Fos", "type": "synonym", "evidence": [ { "id": "A0A9J7G4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7/entry#names_and_taxonomy" } ] }, { "name": "jun dimerization protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016831256", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831256" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613913.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016831256", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831256" } ] }, { "annotation": "Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M4W5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4W5#function" }, { "database": "UniProtKB", "id": "ARBA00045619", "url": "https://www.uniprot.org/uniprotkb/ARBA00045619#function" }, { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Jdp2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7", "locus": {} } ], "crossref": [ { "id": "A0A9J7G4A7", "url": 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"categories": [ "Protein" ] }, { "id": "A0A8C2M4W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY10-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSEVRLLFSRQSPGFQLDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRHRPTCIVRTDSVRTPESEGNPLLEQLDKK", "length": 176, "header": "tr|A0A9J7G4A7-1|A0A9J7G4A7_CRIGR Isoform 1 of Protein c-Fos OS=Cricetulus griseus OX=10029 GN=Jdp2 PE=4 SV=1 CANONICAL=A0A9J7G4A7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M4W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7/entry#A0A8C2M4W5-1", "sequence": { "sequence": "MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRHRPTCIVRTDSVRTPESEGNPLLEQLDKK", "length": 163, "header": "tr|A0A8C2M4W5-1|A0A9J7G4A7_CRIGR Computationally mapped isoform of Protein c-Fos OS=Cricetulus griseus OX=10029 GN=Jdp2 PE=4 SV=1 CANONICAL=A0A9J7G4A7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7/entry#A0A9J7G4A7-1", "sequence": { "sequence": "MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSEVRLLFSRQSPGFQLDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRHRPTCIVRTDSVRTPESEGNPLLEQLDKK", "length": 176, "header": "tr|A0A9J7G4A7-1|A0A9J7G4A7_CRIGR Isoform 1 of Protein c-Fos OS=Cricetulus griseus OX=10029 GN=Jdp2 PE=4 SV=1 CANONICAL=A0A9J7G4A7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7/entry#A0A9J7GWU9-1", "sequence": { "sequence": "MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSEVRLLFSRQSPGFQLDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRLLLVTVFRHGDRSGWCRRNGW", "length": 136, "header": "tr|A0A9J7GWU9-1|A0A9J7GWU9_CRIGR Computationally mapped isoform of Jun dimerization protein 2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Jdp2 PE=4 SV=1 CANONICAL=A0A9J7G4A7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GY10-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7/entry#A0A9J7GY10-1", "sequence": { "sequence": "MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSEVRLLFSRQSPGFQMRKKSEGKGAGRRTKSPRPDAGTRRRSARSFCRGCFWSRCFVTAIEVDGVAEMDGDRP", "length": 138, "header": "tr|A0A9J7GY10-1|A0A9J7GY10_CRIGR Computationally mapped isoform of Jun dimerization protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Jdp2 PE=4 SV=1 CANONICAL=A0A9J7G4A7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M4W5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4W5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M4W5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4W5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759902", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759902", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ADC6-1", "protein_name": "Jun dimerization protein 2", "gene_name": "JDP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRHRPTCIVRTDSVKTPESEGNPLLEQLEKK", "length": 163 }, "evidence": [ { "id": "A0A9J7G4A7", "url": "https://omabrowser.org/oma/group/A0A9J7G4A7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97875-1", "protein_name": "Jun dimerization protein 2", "gene_name": "Jdp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRHRPTCIVRTDSVRTPESEGNPLLEQLDKK", "length": 163 }, "evidence": [ { "id": "A0A9J7G4A7", "url": "https://omabrowser.org/oma/group/A0A9J7G4A7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WYK2-1", "protein_name": "Jun dimerization protein 2", "gene_name": "JDP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMPGQIPDPSVTTGSLPGLGPLTGLPSSALTVEELKYADIRNLGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRHRPTCIVRTDSVKTPESEGNPLLEQLEKK", "length": 163 }, "evidence": [ { "id": "A0A9J7G4A7", "url": "https://omabrowser.org/oma/group/A0A9J7G4A7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 10, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": 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"histone chaperone activity", "id": "GO:0140713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140713", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4A7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G4A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A7" }, { "id": "PS50217", "database": "PROSITE", "url": 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GLYR1 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279762" }, "gene_names": [ { "name": "Glyr1", "type": "recommended", "evidence": [ { "id": "A0A9J7G8F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ] }, { "name": "Glyr1", "type": "synonym", "evidence": [ { "id": "XP_027279762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279762" } ] } ], "protein_names": [ { "name": "Cytokine-like nuclear factor N-PAC", "type": "recommended", "evidence": [ { "id": "A0A9J7G8F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4/entry#names_and_taxonomy" } ] }, { "name": "Glyoxylate reductase 1 homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7G8F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4/entry#names_and_taxonomy" } ] }, { "name": "Nuclear protein NP60", "type": "synonym", "evidence": [ { "id": "A0A9J7G8F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4/entry#names_and_taxonomy" } ] }, { "name": "Putative oxidoreductase GLYR1", "type": "synonym", "evidence": [ { "id": "A0A9J7G8F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4/entry#names_and_taxonomy" } ] }, { "name": "putative oxidoreductase GLYR1 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_027279762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279762" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279762" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Glyr1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4", "locus": {} } ], "crossref": [ { "id": "A0A9J7G8F4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G8F4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05836", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05836", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771020", "url": "https://www.ncbi.nlm.nih.gov/gene/100771020", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006115", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006115", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008927", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008927", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051265", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051265", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771020", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771020", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G8F4", "url": "https://www.orthodb.org/?gene=A0A9J7G8F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43580", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43580", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43580:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43580:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03446", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03446", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279762", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MM93", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MM93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H119", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H119", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H119-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H119-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H281", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H281", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H281-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H281-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9X7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHTSADDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVTSGSTERGSKCLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVAALSRLALDHLFSGSPRPRLTTPKASAGWNCHGRSLQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH", "length": 590, "header": "tr|A0A9J7G8F4-1|A0A9J7G8F4_CRIGR Isoform 1 of Cytokine-like nuclear factor N-PAC OS=Cricetulus griseus OX=10029 GN=Glyr1 PE=3 SV=1 CANONICAL=A0A9J7G8F4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MM93-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4/entry#A0A8C2MM93-1", "sequence": { "sequence": "MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHTSADDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVTSGSTERGSKCLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH", "length": 552, "header": "tr|A0A8C2MM93-1|A0A9J7G8F4_CRIGR Computationally mapped isoform of Cytokine-like nuclear factor N-PAC OS=Cricetulus griseus OX=10029 GN=Glyr1 PE=3 SV=1 CANONICAL=A0A9J7G8F4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4/entry#A0A9J7G8F4-1", "sequence": { "sequence": "MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHTSADDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVTSGSTERGSKCLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVAALSRLALDHLFSGSPRPRLTTPKASAGWNCHGRSLQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH", "length": 590, "header": "tr|A0A9J7G8F4-1|A0A9J7G8F4_CRIGR Isoform 1 of Cytokine-like nuclear factor N-PAC OS=Cricetulus griseus OX=10029 GN=Glyr1 PE=3 SV=1 CANONICAL=A0A9J7G8F4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H119-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4/entry#A0A9J7H119-1", "sequence": { "sequence": "MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHTSADDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVTSGSTERGSKCLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVAALSRLALDHLFSGSPRPRLTTPKASAGWNCHGRSLQASRQEAPCCQPFCSEKPPDCQYGLFGLSNYLQ", "length": 442, "header": "tr|A0A9J7H119-1|A0A9J7H119_CRIGR Computationally mapped isoform of Cytokine-like nuclear factor N-PAC OS=Cricetulus griseus OX=10029 GN=Glyr1 PE=3 SV=1 CANONICAL=A0A9J7G8F4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H281-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4/entry#A0A9J7H281-1", "sequence": { "sequence": "MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHTSADDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVTSGSTERGSKCLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH", "length": 546, "header": "tr|A0A9J7H281-1|A0A9J7H281_CRIGR Computationally mapped isoform of Cytokine-like nuclear factor N-PAC OS=Cricetulus griseus OX=10029 GN=Glyr1 PE=3 SV=1 CANONICAL=A0A9J7G8F4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4/entry#A0A9J7K9X7-1", "sequence": { "sequence": "MHRPQRGGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHTSADDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVTSGSTERGSKCLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVAALSRLALDHLFSGSPRPRLTTPKASAGWNCHGRSLQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH", "length": 584, "header": "tr|A0A9J7K9X7-1|A0A9J7K9X7_CRIGR Computationally mapped isoform of Cytokine-like nuclear factor N-PAC OS=Cricetulus griseus OX=10029 GN=Glyr1 PE=3 SV=1 CANONICAL=A0A9J7G8F4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4/entry#A0A9J7KBD8-1", "sequence": { "sequence": "MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHTSADDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVTSGSTERGSKCLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVAALSRLALDHLFSGSPRPRLTTPKASAGWNCHGRSLQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH", "length": 584, "header": "tr|A0A9J7KBD8-1|A0A9J7KBD8_CRIGR Computationally mapped isoform of Cytokine-like nuclear factor N-PAC OS=Cricetulus griseus OX=10029 GN=Glyr1 PE=3 SV=1 CANONICAL=A0A9J7G8F4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MM93", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM93" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MM93", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM93" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771020", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771020", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" }, { "name": "NAD binding", "id": "GO:0051287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051287", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" }, { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" }, { "name": "NADP binding", "id": "GO:0050661", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" }, { "name": "chromatin-protein adaptor activity", "id": "GO:0140463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140463", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "transcription initiation-coupled chromatin remodeling", "id": "GO:0045815", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045815", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" }, { "name": "transcription elongation-coupled chromatin remodeling", "id": "GO:0140673", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140673", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8F4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G8F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F4" }, { "id": "PS50812", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50812" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 66, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 296, "end_pos": 298 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G4J5-1", "uniprot_ac": "A0A9J7G4J5", "uniprot_id": "A0A9J7G4J5_CRIGR", "mass": { "chemical_mass": 131807.0, "monoisotopic_mass": 131807.0 }, "refseq": { "ac": "XP_016831584", "name": "plakophilin-4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831584" }, "gene_names": [ { "name": "Pkp4", "type": "recommended", "evidence": [ { "id": "A0A9J7G4J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ] }, { "name": "Pkp4", "type": "synonym", "evidence": [ { "id": "XP_016831584", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831584" } ] } ], "protein_names": [ { "name": "Plakophilin-4 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7G4J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#names_and_taxonomy" } ] }, { "name": "plakophilin-4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016831584", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831584" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613966.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016831584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831584" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pkp4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5", "locus": {} } ], "crossref": [ { "id": "A0A9J7G4J5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G4J5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100757509", "url": "https://www.ncbi.nlm.nih.gov/gene/100757509", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", 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"MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1191, "header": "tr|A0A9J7G4J5-1|A0A9J7G4J5_CRIGR Isoform 1 of Plakophilin-4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N7K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A8C2N7K0-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1190, "header": "tr|A0A8C2N7K0-1|A0A9J7G4J5_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7G4J5-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1191, "header": "tr|A0A9J7G4J5-1|A0A9J7G4J5_CRIGR Isoform 1 of Plakophilin-4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7G4S3-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSGSSKPSPIYISSYSSPAREQNRRLQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1147, "header": "tr|A0A9J7G4S3-1|A0A9J7G4S3_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X7 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7G4T7-1", "sequence": { "sequence": "MNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1043, "header": "tr|A0A9J7G4T7-1|A0A9J7G4T7_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X9 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7G6Q8-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSGSSKPSPIYISSYSSPAREQNRRLQQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1148, "header": "tr|A0A9J7G6Q8-1|A0A9J7G6Q8_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X6 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7G6R3-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHERSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1188, "header": "tr|A0A9J7G6R3-1|A0A9J7G6R3_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X5 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G845-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7G845-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1190, "header": "tr|A0A9J7G845-1|A0A9J7G845_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G963-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7G963-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSAPTAVLSR", "length": 1049, "header": "tr|A0A9J7G963-1|A0A9J7G963_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X8 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2B7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7H2B7-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSGSSKPSPIYISSYSSPAREQNRRLQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1146, "header": "tr|A0A9J7H2B7-1|A0A9J7H2B7_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X14 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7H2V4-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHERSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1187, "header": "tr|A0A9J7H2V4-1|A0A9J7H2V4_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X13 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7JKU3-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1189, "header": "tr|A0A9J7JKU3-1|A0A9J7JKU3_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X11 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7JSV5-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHERSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSGSSKPSPIYISSYSSPAREQNRRLQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1144, "header": "tr|A0A9J7JSV5-1|A0A9J7JSV5_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X15 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JU66-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7JU66-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHERSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1188, "header": "tr|A0A9J7JU66-1|A0A9J7JU66_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X12 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JUH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7JUH0-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHERSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV", "length": 1189, "header": "tr|A0A9J7JUH0-1|A0A9J7JUH0_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KA59-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5/entry#A0A9J7KA59-1", "sequence": { "sequence": "MPAPEQASLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDTVHPNNYLIRTEQEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNNQTVNKADSRQHPFTGPTSNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSTTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPAPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPIQYRVQECNYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYKLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKILSESGEGGSPGLKYIVAVSGPPEHLQKGWVESEPFHYTCVHTRARPIQVTPFSVHHQPTDVTHHSVSTNSCTIKMTPPGRPWMHTGCTCSLLVAMKTLILMTEFTFQLLLITQHSMD", "length": 976, "header": "tr|A0A9J7KA59-1|A0A9J7KA59_CRIGR Computationally mapped isoform of Plakophilin-4 isoform X10 OS=Cricetulus griseus OX=10029 GN=Pkp4 PE=3 SV=1 CANONICAL=A0A9J7G4J5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N7K0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N7K0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N7K0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N7K0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757509", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757509", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 13, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "spindle midzone", "id": "GO:0051233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051233", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "midbody", "id": "GO:0030496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030496", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "cell-cell contact zone", "id": "GO:0044291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044291", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" }, { "name": "positive regulation of cytokinesis", "id": "GO:0032467", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032467", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 640, "end_pos": 642, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 691, "end_pos": 693, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" }, { "start_pos": 729, "end_pos": 731, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 851, "end_pos": 853, "annotation": "n_glycosylation_sequon" }, { "start_pos": 966, "end_pos": 968, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 }, { "start_pos": 640, "end_pos": 642 }, { "start_pos": 671, "end_pos": 673 }, { "start_pos": 672, "end_pos": 674 }, { "start_pos": 691, "end_pos": 693 }, { "start_pos": 698, "end_pos": 700 }, { "start_pos": 729, "end_pos": 731 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 851, "end_pos": 853 }, { "start_pos": 966, "end_pos": 968 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G8W8-1", "uniprot_ac": "A0A9J7G8W8", "uniprot_id": "A0A9J7G8W8_CRIGR", "mass": { "chemical_mass": 68780.0, "monoisotopic_mass": 68780.0 }, "refseq": { "ac": "XP_007619604", "name": "WD repeat-containing protein 76 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007619604" }, "gene_names": [ { "name": "Wdr76", "type": "recommended", "evidence": [ { "id": "A0A9J7G8W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8" } ] }, { "name": "Wdr76", "type": "synonym", "evidence": [ { "id": "XP_007619604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007619604" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 76", "type": "recommended", "evidence": [ { "id": "A0A9J7G8W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 76 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007619604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007619604" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007619604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007619604" } ] }, { "annotation": "Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.", "evidence": [ { "database": "UniProtKB", "id": "G3H0T6", "url": "https://www.uniprot.org/uniprotkb/G3H0T6#function" }, { "database": "UniProtKB", "id": "ARBA00002530", "url": "https://www.uniprot.org/uniprotkb/ARBA00002530#function" }, { "database": "UniProtKB", "id": "RU365004", "url": "https://www.uniprot.org/uniprotkb/RU365004#function" }, { "database": "UniProtKB", "id": "A0A9J7G737", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G737#function" }, { "database": "UniProtKB", "id": "A0A9J7G8W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8#function" }, { "database": "UniProtKB", "id": "A0A9J7JZW0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZW0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wdr76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8", "locus": {} } ], "crossref": [ { "id": "A0A9J7G8W8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G8W8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100753189", "url": "https://www.ncbi.nlm.nih.gov/gene/100753189", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753189", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753189", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DPNTLYW", "url": "https://omabrowser.org/oma/group/DPNTLYW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G8W8", "url": "https://www.orthodb.org/?gene=A0A9J7G8W8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3H0T6", "url": "https://www.orthodb.org/?gene=G3H0T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14773", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14773", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14773:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14773:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007619604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007619604", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G737", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G737", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G737-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G737-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZW0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H0T6", "url": "https://www.uniprot.org/uniprotkb/G3H0T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H0T6-1", "url": "https://www.uniprot.org/uniprotkb/G3H0T6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGCNAEAEEKAGSKQCPQVQVNEYKENGNCAYTSLRPIQTTTSGKTAKAYCLSPFSLSNSKRARFKLSTSPFESHPNNAVACKKTGRKKTCRKGVTSKMKAVSSKAESLLLKPPVDAYTDSELRHSSTAESVTLSVDMGSSDEDSAPGLGDFSELSPYERKRLKNIKENANFFASLELSESAARLRGMIKKRQPPESKRKRPKKKENEIGCRRSMRLLKVDPLGVSLPAAPTQPMLEEEEENPLLPPGPLEMIPENQDDSNELFRASLKTWADMSKTSNERTKEGLSSIKSYKANLSGMVISEATVRKVTRGAISSVALHPSEVRTLVAAGAKSGQIGLWDLTRQCEDGVYVFYPHSQPVSCLYFSPTNPAHLLSLSYDGTLRCGDFSSAVFEEVYRNEGNSPSSFDFLAKDASTLLVGHWDGHLSLVDRRTPGTSHEKFFNSSMGKIRTVHVHPVSRQYFITAGLRDVHVYDVRCLNSRGSQPMISLAEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSLSSQIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCFIVGSMAHPRRVEVFHETGESVRSLSGDCLVSVCSLSVMHPTRYVLAGGNSSGRLHVFMSQESF", "length": 624, "header": "tr|A0A9J7G8W8-1|A0A9J7G8W8_CRIGR Isoform 1 of WD repeat-containing protein 76 OS=Cricetulus griseus OX=10029 GN=Wdr76 PE=3 SV=1 CANONICAL=A0A9J7G8W8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G737-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8/entry#A0A9J7G737-1", "sequence": { "sequence": "MIKKRQPPESKRKRPKKKENEIGCRRSMRLLKVDPLGVSLPAAPTQPMLEEEEENPLLPPGPLEMIPENQDDSNELFRASLKTWADMSKTSNERTKEGLSSIKSYKANLSGMVISEATVRKVTRGAISSVALHPSEVRTLVAAGAKSGQIGLWDLTRQCEDGVYVFYPHSQPVSCLYFSPTNPAHLLSLSYDGTLRCGDFSSAVFEEVYRNEGNSPSSFDFLAKDASTLLVGHWDGHLSLVDRRTPGTSHEKFFNSSMGKIRTVHVHPVSRQYFITAGLRDVHVYDVRCLNSRGSQPMISLAEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSLSSQIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCFIVGSMAHPRRVEVFHETGESVRSLSGDCLVSVCSLSVMHPTRYVLAGGNSSGRLHVFMSQESF", "length": 436, "header": "tr|A0A9J7G737-1|A0A9J7G737_CRIGR Computationally mapped isoform of WD repeat-containing protein 76 OS=Cricetulus griseus OX=10029 GN=Wdr76 PE=3 SV=1 CANONICAL=A0A9J7G8W8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8/entry#A0A9J7G8W8-1", "sequence": { "sequence": "MSGCNAEAEEKAGSKQCPQVQVNEYKENGNCAYTSLRPIQTTTSGKTAKAYCLSPFSLSNSKRARFKLSTSPFESHPNNAVACKKTGRKKTCRKGVTSKMKAVSSKAESLLLKPPVDAYTDSELRHSSTAESVTLSVDMGSSDEDSAPGLGDFSELSPYERKRLKNIKENANFFASLELSESAARLRGMIKKRQPPESKRKRPKKKENEIGCRRSMRLLKVDPLGVSLPAAPTQPMLEEEEENPLLPPGPLEMIPENQDDSNELFRASLKTWADMSKTSNERTKEGLSSIKSYKANLSGMVISEATVRKVTRGAISSVALHPSEVRTLVAAGAKSGQIGLWDLTRQCEDGVYVFYPHSQPVSCLYFSPTNPAHLLSLSYDGTLRCGDFSSAVFEEVYRNEGNSPSSFDFLAKDASTLLVGHWDGHLSLVDRRTPGTSHEKFFNSSMGKIRTVHVHPVSRQYFITAGLRDVHVYDVRCLNSRGSQPMISLAEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSLSSQIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCFIVGSMAHPRRVEVFHETGESVRSLSGDCLVSVCSLSVMHPTRYVLAGGNSSGRLHVFMSQESF", "length": 624, "header": "tr|A0A9J7G8W8-1|A0A9J7G8W8_CRIGR Isoform 1 of WD repeat-containing protein 76 OS=Cricetulus griseus OX=10029 GN=Wdr76 PE=3 SV=1 CANONICAL=A0A9J7G8W8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8/entry#A0A9J7JZW0-1", "sequence": { "sequence": "MQTFLLPLSYLRKRPKKKENEIGCRRSMRLLKVDPLGVSLPAAPTQPMLEEEEENPLLPPGPLEMIPENQDDSNELFRASLKTWADMSKTSNERTKEGLSSIKSYKANLSGMVISEATVRKVTRGAISSVALHPSEVRTLVAAGAKSGQIGLWDLTRQCEDGVYVFYPHSQPVSCLYFSPTNPAHLLSLSYDGTLRCGDFSSAVFEEVYRNEGNSPSSFDFLAKDASTLLVGHWDGHLSLVDRRTPGTSHEKFFNSSMGKIRTVHVHPVSRQYFITAGLRDVHVYDVRCLNSRGSQPMISLAEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSLSSQIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCFIVGSMAHPRRVEVFHETGESVRSLSGDCLVSVCSLSVMHPTRYVLAGGNSSGRLHVFMSQESF", "length": 436, "header": "tr|A0A9J7JZW0-1|A0A9J7JZW0_CRIGR Computationally mapped isoform of WD repeat-containing protein 76 OS=Cricetulus griseus OX=10029 GN=Wdr76 PE=3 SV=1 CANONICAL=A0A9J7G8W8-1" }, "locus": {} }, { "isoform_ac": "G3H0T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8/entry#G3H0T6-1", "sequence": { "sequence": "MKAVSSKAESLLLKPPVDAYTDSELRHSSTAESVTLSVDMGSSDEDSAPGLGDFSELSPYERKRLKNIKENANFFASLELSESAARLRGMIKKRQPPESKRKRPKKKENEIGCRRSMRLLKVDPLGVSLPAAPTQPMLEEEEENPLLPPGPLEMIPENQDDSNELFRASLKTWADMSKTSNERTKEGLSSIKSYKANLSGMVISEATVRKVTRGAISSVALHPSEVRTLVAAGAKSGQIGLWDLTRQCEDGVYVFYPHSQPVSCLYFSPTNPAHLLSLSYDGTLRCGDFSSAVFEEVYRNEGNSPSSFDFLAKDASTLLVGHWDGHLSLVDRRTPGTSHEKFFNSSMGKIRTVHVHPVSRQYFITAGLRDVHVYDVRCLNSRGSQPMISLAEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSLSSQIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCFIVGSMAHPRRVEVFHETGESVRSLSGDCLVSVCSLSVMHPTRYVLAGGNSSGRLHVFMSQESF", "length": 525, "header": "tr|G3H0T6-1|A0A9J7G8W8_CRIGR Computationally mapped isoform of WD repeat-containing protein 76 OS=Cricetulus griseus OX=10029 GN=Wdr76 PE=3 SV=1 CANONICAL=A0A9J7G8W8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H0T6", "url": "https://www.uniprot.org/uniprotkb/G3H0T6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H0T6", "url": "https://www.uniprot.org/uniprotkb/G3H0T6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753189", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753189", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9Q1Q9-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "wdr76", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDTDKSDLSLETMKLLQERTPPQNPGMDGSVLRTSRRIKEKQNQRKKQNLPPKCLTFRSEVKSTKRVVKRRISGSEKEKEVKRSKADPDHESLPQGYREGLSEYQLERLENIRKNQAFLNSLNLTEISEALRPKQKPTQKGLKKEKTQVEMLPVRKSLRLQNKGPQSTTATEFTFPTTYELEKEAKPPGPIPLDPINLDEDATLPDDLLDVWNEVPLEQSTGTPDLKSYERMLKKLSIDDSRVVKVVKERICCAAFHPSSNLLMAAGDKYGHLGLWRPDAEWGDDGVVCFEPHSRAITALAFTSQPCNLITASYDGSARSMDLEKAVFDEVYRSSSSLKSFDFLSSDCSTLLFGEWNGDVAVVDRRTGNLCESLHAMTAAPLRGVHVHPVQQHYFLVAESSFVNIYDLRHLKKRNSPAVCELYGHNRSTSSAFFSPLTGSRVLTTCMDDCIRVFDSSQIAGRIPALTSIRHNMQTGRWLSRLCAVWDPKHQECFVIGTMDRPRKIKVYHESGRLLHTLQNTEHLTTVCSVTAFHPSRNALLGGNASGRLHIYTD", "length": 554 }, "evidence": [ { "id": "A0A9J7G8W8", "url": "https://omabrowser.org/oma/group/A0A9J7G8W8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6PWY4-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "Wdr76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGSKAESEEKAGSKQCPLVQVNEYKENEHIAYTSLRPIQITTLRKTAKVYLYPFSLSNSKLGLLKLSKSPVVNNSSKSVVHKKKDRKKTRRKVLTSKMKALSSKADSLLLKSSVDAYTESTRLGPKRTSDSATLSVDAESSDEDSAPGLDDFSGLSPYERKRLRNIRENANFFASLQLAESAARLRGMIKKRESPESKRKRPKKKENEIGCRRSMRLLKVDPLGVSLPASPTQPTLVEEEENPLLPPGPLEMIPENQDDSSELLKASLKTWAEMSQTSNEKTKKGLSSIKSYKANLSGMVISEATVRKVTKGAISSVALHPSEVRTLVAAGAKSGQIGLWDLTQQSEDAMYVFYAHSRYVSCLSFSPTNPAHLLSLSYDGTLRCGDFSSAVFEEVYRNEGNSPSSFDFLNDSSSLLVGHWDGHLSLVDRRTPGTSYEKFFNSSLEKIRTVHVHPLSRQYFVTAGLRDVHVYDARFLKSRGSQPLISLTEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSISSQLPLLSTIRHNTVTGRWLTRFQAVWDPKQEDCFIVGSMDHPRRVEVFHESGKNVHSLWGECLVSVCSLSAVHPTRYILAGGNSSGKLHVFMHQET", "length": 622 }, "evidence": [ { "id": "A0A9J7G8W8", "url": "https://omabrowser.org/oma/group/A0A9J7G8W8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZJT1-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "Wdr76", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGFIAVAEEKAGSKQCPQVQVNEYKENENIAYTSLRPIQITTRRKAAKVYLYPFSLSNPKLGLFKLSKSPVENKSSSEMVQKKTDQKKTCRRVLTSKMKALSSKAESCLLKPALDSHTESSELEHKSISDPVTPSVDMESSDEDSAPGPDDFSGLSPYERKRMKNIRENANFFASLQLAESAARLRGMIKKNQPPESKRKRPKKKENEVGCRRSMRLLKVDPLGVSLPASLTQPTLVEEETPMIPPGPLEMIPENQDDCSELFKASLKTWAEMSQTSNEKTKKGLSSIKSYKASLSGMVVSEATIRKVTKGAISSVAIHPSGVRTLVAAGSKSGQVGLWDLTQQSEDGAYAFCPHSQPVSCLSFSPTNPAHLLSLSYDGTVRCGDFSTAVFEEVYRNERNSLSSFDFLDDASTLLVGHWSGHLSLVDRRTPGTSYEKFINSSLEKIRTVHVHPLSRQYFITAGLRDVHVYDVRCLKSGKSQPLISLTEHSKSIASAYFSPVTGNRVVTTCADCKLRVFDSSSLSSQFPLVSTIRHNTITGRWLTRFQAVWDPKQEDCFTVGSMAHPRRVEVFHETGKNVHSFGGECLVSVCSLSVMHPTRYILAGGNCSGRLHVFMHQET", "length": 621 }, "evidence": [ { "id": "A0A9J7G8W8", "url": "https://omabrowser.org/oma/group/A0A9J7G8W8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BHI0-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "WDR76", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGSRAEAEQKGGSRQRLQVNEYKENQNIADTSLRPVQTTVLGVTAKVCLVPFSLSNYNTGQLKRPKSLLDKNSNSEVTCKKSKKAEIKKSCRRLLTPKMEATSSKEESTLQKSSLDVHAESNKWQYKSPSDTVVLSPDTESSQEGDSDEDTTPGLDDFSELSPYERKRLKNISENANFFASLQLSESAARFREMIKKRQPPESKRKKPKKKENETGCRRSMRLLKVDPSGVPLPAAPIQTVLEVDENPLIPPGPLEMTPENQDDDNALFKGFLQTWAEMSKTRSKNTEKELSSIKSYKVHLNGMVISEDTVCKVTRGSISSMAIHPSEMRTLVAAGAKSGQVGLWDLTHQPKEDGVYLFQPHSQPVSCLYFSPANPAHLLSLSYDGTLRCGDFSRAVFEEVYRDETRSFSSFDFLTEDASTLIVGHWDGSMSLVDRRTPGTSCEKLIKTSLSKIRTVHVHPVQRQYLITAGLRDIHVYDARCLNLSRNQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCKLRIFDSSCISSKIPLLTTIRHNTITGRWLTRFQAVWDPKQEDCIVVGSMAQPRRVEVFHETGKWVHSFLGGECLASVCSINAMHPTRYILAGGNSSGRVHVFMN", "length": 627 }, "evidence": [ { "id": "A0A9J7G8W8", "url": "https://omabrowser.org/oma/group/A0A9J7G8W8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q12510-1", "protein_name": "DNA damage-binding protein CMR1", "gene_name": "CMR1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPELTEFQKKRLENIKRNNDLLKKLHLSGVASQIKHEAGVLEKSRAPAKKKQKTTNTRATKSASPTLPTRRSRRLRGESADDVKGIPNVNDNQLLKMGSPDGQDKNFIDAIKEKPVIGDVKLSDLIKDEDESALLEKFKRFNNGNFSSGDFFEEIKKRQGDVTGMDEFDLDLYDVFQPNEIKITYERISATYFHPAMEKKLIIAGDTSGTVGFWNVRDEPLADSEEDRMEEPDITRVKLFTKNVGRIDCFPADTSKILLTSYDGSIRSVHLNNLQSEEVLTLKNEYDDSLGISDCQFSYENPNVLFLTTLGGEFTTFDTRVKKSEYNLRRLADKKIGSMAINPMRPYEIATGSLDRTLKIWDTRNLVKKPEWSQYEDYPSHEIVSTYDSRLSVSAVSYSPTDGTLVCNGYDDTIRLFDVKSRDHLSAKLEPKLTIQHNCQTGRWTSILKARFKPNKNVFAIANMKRAIDIYNSEGQQLAHLPTATVPAVISWHPLRNWIAGGNSSGKIFLFTDDSGTIKQEE", "length": 522 }, "evidence": [ { "id": "A0A9J7G8W8", "url": "https://omabrowser.org/oma/group/A0A9J7G8W8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9H967-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "WDR76", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSGAAAEKADSRQRPQMKVNEYKENQNIAYVSLRPAQTTVLIKTAKVYLAPFSLSNYQLDQLMCPKSLSEKNSNNEVACKKTKIKKTCRRIIPPKMKNTSSKAESTLQNSSSAVHTESNKLQPKRTADAMNLSVDVESSQDGDSDEDTTPSLDFSGLSPYERKRLKNISENADFFASLQLSESAARLREMIEKRQPPKSKRKKPKRENGIGCRRSMRLLKVDPSGVSLPAAPTPPTLVADETPLLPPGPLEMTSENQEDNNERFKGFLHTWAGMSKPSSKNTEKGLSSIKSYKANLNGMVISEDTVYKVTTGPIFSMALHPSETRTLVAVGAKFGQVGLCDLTQQPKEDGVYVFHPHSQPVSCLYFSPANPAHILSLSYDGTLRCGDFSRAIFEEVYRNERSSFSSFDFLAEDASTLIVGHWDGNMSLVDRRTPGTSYEKLTSSSMGKIRTVHVHPVHRQYFITAGLRDTHIYDARRLNSRRSQPLISLTEHTKSIASAYFSPLTGNRVVTTCADCNLRIFDSSCISSKIPLLTTIRHNTFTGRWLTRFQAMWDPKQEDCVIVGSMAHPRRVEIFHETGKRVHSFGGEYLVSVCSINAMHPTRYILAGGNSSGKIHVFMNEKSC", "length": 626 }, "evidence": [ { "id": "A0A9J7G8W8", "url": "https://omabrowser.org/oma/group/A0A9J7G8W8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SAI7-1", "protein_name": "WD repeat-containing protein 76", "gene_name": "DRS1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATEYERKRLENIRRNDEMLAALNVRAKASSLLSAAKRSRDDSKSFKKKKPKPASTPTVIRMSLRTRGLNPDSAGLPDGFSDFRMGSQITHNQPSPQKQSPRLLAPIPFESAYEGYGSYTQLVDTLLGIESKSCRGKLVKGEIGVVKDENESPMVRTRSSSRVSKVSVKKEEPEDDSFSDYVNKEFSIPVKPEKIEFDLDLLTLEPQNVARVVPGRIFVVQFLPCENVKMVAAGDKLGNVGFWNLDCGNEEDNDGIYLFTPHSAPVSSIVFQQNSLSRVISSSYDGLIRLMDVEKSVFDLVYSTDEAIFSLSQRPNDEQSLYFGQDYGVFNVWDLRAGKSVFHWELHERRINSIDFNPQNPHVMATSSTDGTACLWDLRSMGAKKPKTLSTVNHSRAVHSAYFSPSGLSLATTSLDNYIGVLSGANFENTCMIYHNNTSRWISKFKAVWGWDDSYIYVGNLSKKIDVINPKLKRTVMELHNPLQRAIPCRIHCHPYNVGTLAGSTAGGQVYVWTTK", "length": 516 }, "evidence": [ { "id": "A0A9J7G8W8", "url": "https://omabrowser.org/oma/group/A0A9J7G8W8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA damage checkpoint", "id": "GO:2000001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000001", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8" } ], "pmid": "" }, { "name": "heterochromatin", "id": "GO:0000792", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000792", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8" } ], "pmid": "" }, { "name": "site of DNA damage", "id": "GO:0090734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090734", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8W8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 296, "end_pos": 298 }, { "start_pos": 443, "end_pos": 445 }, { "start_pos": 610, "end_pos": 612 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GA36-1", "uniprot_ac": "A0A9J7GA36", "uniprot_id": "A0A9J7GA36_CRIGR", "mass": { "chemical_mass": 39567.0, "monoisotopic_mass": 39567.0 }, "refseq": { "ac": "XP_007640259", "name": "SH3 domain-containing YSC84-like protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640259" }, "gene_names": [ { "name": "Sh3yl1", "type": "recommended", "evidence": [ { "id": "A0A9J7GA36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36" } ] }, { "name": "Sh3yl1", "type": "synonym", "evidence": [ { "id": "XP_007640259", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640259" } ] } ], "protein_names": [ { "name": "SH3 domain-containing YSC84-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7GA36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36/entry#names_and_taxonomy" } ] }, { "name": "SH3 domain-containing YSC84-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007640259", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640259" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613848.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640259", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640259" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA36", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sh3yl1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36", "locus": {} } ], "crossref": [ { "id": "A0A9J7GA36", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GA36", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11525", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11525", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11841", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11841", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752304", "url": "https://www.ncbi.nlm.nih.gov/gene/100752304", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035511", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035511", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051702", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051702", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752304", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752304", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SNCKARN", "url": "https://omabrowser.org/oma/group/SNCKARN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GA36", "url": "https://www.orthodb.org/?gene=A0A9J7GA36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GF40", "url": "https://www.orthodb.org/?gene=A0A9J7GF40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HBH3", "url": "https://www.orthodb.org/?gene=G3HBH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15629", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15629", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15629:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15629:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640259", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640259", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GA36", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GA36-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GF40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GF40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HBH3", "url": "https://www.uniprot.org/uniprotkb/G3HBH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HBH3-1", "url": "https://www.uniprot.org/uniprotkb/G3HBH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLKYILKLDVFSPSVVCFFNLSVNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAVLSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDKAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAGISLEGSCLIERKETNKKFYCQDIRAYDILFGDVPQPAQAEDLYEILNSFTEKYENEGQRINLRKVAREQRKAKELPPKPSSRPQQSRAPVQLNSGSQSNGNGYKLYPELSSYHEKNGSLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN", "length": 363, "header": "tr|A0A9J7GA36-1|A0A9J7GA36_CRIGR Isoform 1 of SH3 domain-containing YSC84-like protein 1 OS=Cricetulus griseus OX=10029 GN=Sh3yl1 PE=3 SV=1 CANONICAL=A0A9J7GA36-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GA36-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36/entry#A0A9J7GA36-1", "sequence": { "sequence": "MKLKYILKLDVFSPSVVCFFNLSVNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAVLSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDKAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAGISLEGSCLIERKETNKKFYCQDIRAYDILFGDVPQPAQAEDLYEILNSFTEKYENEGQRINLRKVAREQRKAKELPPKPSSRPQQSRAPVQLNSGSQSNGNGYKLYPELSSYHEKNGSLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN", "length": 363, "header": "tr|A0A9J7GA36-1|A0A9J7GA36_CRIGR Isoform 1 of SH3 domain-containing YSC84-like protein 1 OS=Cricetulus griseus OX=10029 GN=Sh3yl1 PE=3 SV=1 CANONICAL=A0A9J7GA36-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GF40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36/entry#A0A9J7GF40-1", "sequence": { "sequence": "MKLKYILKLDVFSPSVVCFFNLSVNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAVLSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDKAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAGISLEGSCLIERKETNKKFYCQDIRAYDILFGDVPQPAQAEDLYEILNSFTEKYENEGQRINLRKVAREQRKAKELPPKPSSRPQQSRAPVQLNSGSQSNGNGYKLYPELSSYHEKNGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN", "length": 347, "header": "tr|A0A9J7GF40-1|A0A9J7GF40_CRIGR Computationally mapped isoform of SH3 domain-containing YSC84-like protein 1 OS=Cricetulus griseus OX=10029 GN=Sh3yl1 PE=3 SV=1 CANONICAL=A0A9J7GA36-1" }, "locus": {} }, { "isoform_ac": "G3HBH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36/entry#G3HBH3-1", "sequence": { "sequence": "MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAVLSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDKAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAGISLEGSCLIERKETNKKFYCQDIRAYDILFGDVPQPAQAEDLYEILNSFTEKYENEGQRINLRKVAREQRKAKELPPKPSSRPQQSRAPVQLNSGSQSNGNGYKLYPELSSYHEKNGSLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN", "length": 340, "header": "tr|G3HBH3-1|A0A9J7GA36_CRIGR Computationally mapped isoform of SH3 domain-containing YSC84-like protein 1 OS=Cricetulus griseus OX=10029 GN=Sh3yl1 PE=3 SV=1 CANONICAL=A0A9J7GA36-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HBH3", "url": "https://www.uniprot.org/uniprotkb/G3HBH3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HBH3", "url": "https://www.uniprot.org/uniprotkb/G3HBH3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752304", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752304", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UN95-1", "protein_name": "SH3 domain-containing YSC84-like protein 1", "gene_name": "SH3YL1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFELGIEVSDLVIILNYGRAVEAFAKGGNLTLGGNCTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAGISLEGSCLIERKETNRKFYCQDVRAYDILFGDIPRPAQAEDLYEVLDSFTEKYESEGQRINARKAAREQKKAQAKELPPKPLSRPQQSSAQVQLNSGSQSNRNEYKLYPELPSYHERVGSLNQPTEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGELRGQTGIFPANYVTMN", "length": 342 }, "evidence": [ { "id": "A0A9J7GA36", "url": "https://omabrowser.org/oma/group/A0A9J7GA36/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XHH4-1", "protein_name": "SH3 domain-containing YSC84-like protein 1", "gene_name": "SH3YL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDLWSDTTCMYYWEALLLINLQMVGVDTSKIVNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPPHVIAKAKGLAVLSVIKAGFLVTARGGSGIVLARLPNGTWSAPSAIGIAGLGGGFEIGIEVSDLVIILNHERAVEAFAKGGNLTLGGNLTVAIGPLGRNLEGDVALRSSAAVYTYCKSRGLFAGVSLEGTCLIERKETNRKFYGQDIRASAILLGDVPFPAQAEDLYETLASFIEVYENEEQRNNPGKAVNDPPGRPSRPEPHKPSVRPTPPAKKNSNKLYPELPSDYASLSNSTSNPVEVTALYSFEGQQPGDLTFKAGDKIIVTTKTGSQFDWWEGRIGGQTGIFPANYVAISND", "length": 365 }, "evidence": [ { "id": "A0A9J7GA36", "url": "https://omabrowser.org/oma/group/A0A9J7GA36/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B0BNA1-1", "protein_name": "SH3 domain-containing YSC84-like protein 1", "gene_name": "Sh3yl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAVLSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAGISLEGSCLIERKETNRKFYCQDIRAYDILFGDVPQPAQAEDLYEILNSFTEKYETEGQRINLKKVAREQRKAKELPPKPSSRPQPSRPPVQLNAGSQSNRNEYKLYPELSSYHEKTGSLSQPIEVTALYSFEGQQPGDLNFQAGDRIIVISKTDSNFDWWEGKLRGQTGIFPANYVTMN", "length": 340 }, "evidence": [ { "id": "A0A9J7GA36", "url": "https://omabrowser.org/oma/group/A0A9J7GA36/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O08641-1", "protein_name": "SH3 domain-containing YSC84-like protein 1", "gene_name": "Sh3yl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAVLSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNFTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAGISLEGSCLIERKETNRKFYCQDIRAYDILFGDVPQPAQAEDLYEILNSFTEKYETEGQRINLKKVAREQRKAKELPPKPSSRPQPAHPPVQLNAGSQGNRNEYKLYPELSSYHEKTGNLNQPIEVTALYSFEGQQPGDLNFQAGDRIIVISKTDSNFDWWEGKLRGQTGIFPANYVTMN", "length": 340 }, "evidence": [ { "id": "A0A9J7GA36", "url": "https://omabrowser.org/oma/group/A0A9J7GA36/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P43603-1", "protein_name": "LAS seventeen-binding protein 3", "gene_name": "LSB3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGINNPIPRSLKSETKKAAKILASFVKPNQVFGADQVIPPDVLKRAKGLAIITILKAGFLFSGRAGSGVIVARLKDGTWSAPSAIAMAGAGAGGMVGIELTDFVFILNTQDAVKSFSEFGTITLGGNVSVSAGPLGRSAEAAASASAGGVAAVFAYSKSKGLFAGVSVEGSAIIERREANRKFYGDNCTAKMILSGRIRPPPAVDPLFRVLESRAFNYRPSNGGRGSFDDDEDDYYDDDDYYNDIPSSFSSTDASSTRPNTRSTRRRAQSGSRYTFDDDDDDDDYGTGYSRNSRLAPTNSGGSGGKLDDPSGASSYYASHRRSGTAQSRARSSRNRWADDEYDDYDDDYESGYRRGNGRDRTKDREVDDLSNRFSKSRISSASTPQTSQGRFTAPTSPSTSSPKAVALYSFAGEESGDLPFRKGDVITILKKSDSQNDWWTGRVNGREGIFPANYVELV", "length": 459 }, "evidence": [ { "id": "A0A9J7GA36", "url": "https://omabrowser.org/oma/group/A0A9J7GA36/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3SZ01-1", "protein_name": "SH3 domain-containing YSC84-like protein 1", "gene_name": "SH3YL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVTARGGSGIVLARLPDGKWSAPSAIGIAGLGGGFELGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNLTVAVGPLGRNLEGNVSLRSSAAVFTYCKSRGLFAGISLEGSCLIERKETNRKFYCQDIRAYDILFGDITRPAQAEDLYEVLDSFTEKYEIEGQRVNARRAAREQKKASAKLPPKPSSRPEQSSAQVQLSSGSQSSRNEYNLYPELSSYRERVGNSNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGRTGIFPANYVTMN", "length": 341 }, "evidence": [ { "id": "A0A9J7GA36", "url": "https://omabrowser.org/oma/group/A0A9J7GA36/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96HL8-1", "protein_name": "SH3 domain-containing YSC84-like protein 1", "gene_name": "SH3YL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVTARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFYCQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN", "length": 342 }, "evidence": [ { "id": "A0A9J7GA36", "url": "https://omabrowser.org/oma/group/A0A9J7GA36/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X1WFC4-1", "protein_name": "SH3 domain-containing YSC84-like protein 1", "gene_name": "sh3yl1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNNPIPANLKSEAKKAAKILREFTEISNRMGPDKLIPAHVIAKAQGLAILSVFKAGFMITARGGSGIVIARLADGSWSAPSAIGIAGLGGGFEIGLESSDFVIILNQRRAVEAFSKGGNLTLGGNFTVAVGPLGRNVEADVAVRSTAAVYSYCKSRGLYAGVSLVGSYLIERKDTNRKFYGKDIRASAILNGDVEPPPEAYDLYTILQDYTEKYTTEWQNKHMRSSSKMSSAPARPRPPTQKSASSYTPRTQAPPAVKPALYPNLNSWDTGSDQASGGALVVTAVHPFTGQQPGDLSFNAGDRITVVTKTDSQYDWWEGELKGQVGIFPANFVSYS", "length": 336 }, "evidence": [ { "id": "A0A9J7GA36", "url": "https://omabrowser.org/oma/group/A0A9J7GA36/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of ruffle assembly", "id": "GO:1900027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900027", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA36", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA36", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA36", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA36", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA36" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": 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{ "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 148, "end_pos": 150 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 21, "end_pos": 23 }, { "start_pos": 300, "end_pos": 302 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G3I2-1", "uniprot_ac": "A0A9J7G3I2", "uniprot_id": "A0A9J7G3I2_CRIGR", "mass": { "chemical_mass": 77974.0, "monoisotopic_mass": 77974.0 }, "refseq": { "ac": "XP_007641381", "name": "PWWP domain-containing DNA repair factor 3A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641381" }, "gene_names": [ { "name": "Pwwp3a", "type": "recommended", "evidence": [ { "id": "A0A9J7G3I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2" } ] }, { "name": "Pwwp3a", "type": "synonym", "evidence": [ { "id": "XP_007641381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641381" } ] } ], "protein_names": [ { "name": "PWWP domain-containing DNA repair factor 3A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007641381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641381" }, { "id": "A0A9J7G3I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613904.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007641381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641381" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pwwp3a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2", "locus": {} } ], "crossref": [ { "id": "cd06080", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06080", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766402", "url": "https://www.ncbi.nlm.nih.gov/gene/100766402", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR035504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766402", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766402", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PPWAHRC", "url": "https://omabrowser.org/oma/group/PPWAHRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G3H9", "url": "https://www.orthodb.org/?gene=A0A9J7G3H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G3I2", "url": "https://www.orthodb.org/?gene=A0A9J7G3I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JQE9", "url": "https://www.orthodb.org/?gene=A0A9J7JQE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HF72", "url": "https://www.orthodb.org/?gene=G3HF72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31333:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31333:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007641381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641381", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G3H9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HF72", "url": "https://www.uniprot.org/uniprotkb/G3HF72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HF72-1", "url": "https://www.uniprot.org/uniprotkb/G3HF72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTDAKYVLCRWEKRLWPAKVLAITETSVKNRRKKELFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPAAPLEELTYRRSLRVALDLLNERTNLSPESHLMKDETTLSQKEKPHADMASWIPSAPSLSFHGEDGEDVAAQRISKSRWEYVPQSLSGLSASEEDPRCKVDRKTGLSKNGTPRAALLSPTGDGSRDSSGSRLDRGQEDTTSKRRRDLGEKPTRRHKTESRLSKGESVVENEGQASSCVTPASPRLLSQTWEEDPCAGVKGFDRVVPSGSSRLLPASERGRRHPTKRPRLDGGQNPQARQLGTGTVGAVPSLRSWSGEAMVLRSAGDNDKPEEADPVSSEESTGFKSIHSLLEDEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHTLLERAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISHPVRKSIQQDVLGTRFPQLGKGDAEEPVGDSRPGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSGQYVTCVETYLEDEAQLDEVVEYLQGICRDMDGEVPARGSGDRIRFVLDVLLPEAIICAISAVESVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR", "length": 692, "header": "tr|A0A9J7G3I2-1|A0A9J7G3I2_CRIGR Isoform 1 of PWWP domain-containing DNA repair factor 3A isoform X1 OS=Cricetulus griseus OX=10029 GN=Pwwp3a PE=3 SV=1 CANONICAL=A0A9J7G3I2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G3H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2/entry#A0A9J7G3H9-1", "sequence": { "sequence": "MKDETTLSQKEKPHADMASWIPSAPSLSFHGEDGEDVAAQRISKSRWEYVPQSLSGLSASEEDPRCKVDRKTGLSKNGTPRAALLSPTGDGSRDSSGSRLDRGQEDTTSKRRRDLGEKPTRRHKTESRLSKGESVVENEGQASSCVTPASPRLLSQTWEEDPCAGVKGFDRVVPSGSSRLLPASERGRRHPTKRPRLDGGQNPQARQLGTGTVGAVPSLRSWSGEAMVLRSAGDNDKPEEADPVSSEESTGFKSIHSLLEDEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHTLLERAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISHPVRKSIQQDVLGTRFPQLGKGDAEEPVGDSRPGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSGQYVTCVETYLEDEAQLDEVVEYLQGICRDMDGEVPARGSGDRIRFVLDVLLPEAIICAISAVESVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR", "length": 582, "header": "tr|A0A9J7G3H9-1|A0A9J7G3H9_CRIGR Computationally mapped isoform of PWWP domain-containing DNA repair factor 3A isoform X4 OS=Cricetulus griseus OX=10029 GN=Pwwp3a PE=3 SV=1 CANONICAL=A0A9J7G3I2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2/entry#A0A9J7G3I2-1", "sequence": { "sequence": "MTDAKYVLCRWEKRLWPAKVLAITETSVKNRRKKELFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPAAPLEELTYRRSLRVALDLLNERTNLSPESHLMKDETTLSQKEKPHADMASWIPSAPSLSFHGEDGEDVAAQRISKSRWEYVPQSLSGLSASEEDPRCKVDRKTGLSKNGTPRAALLSPTGDGSRDSSGSRLDRGQEDTTSKRRRDLGEKPTRRHKTESRLSKGESVVENEGQASSCVTPASPRLLSQTWEEDPCAGVKGFDRVVPSGSSRLLPASERGRRHPTKRPRLDGGQNPQARQLGTGTVGAVPSLRSWSGEAMVLRSAGDNDKPEEADPVSSEESTGFKSIHSLLEDEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHTLLERAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISHPVRKSIQQDVLGTRFPQLGKGDAEEPVGDSRPGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSGQYVTCVETYLEDEAQLDEVVEYLQGICRDMDGEVPARGSGDRIRFVLDVLLPEAIICAISAVESVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR", "length": 692, "header": "tr|A0A9J7G3I2-1|A0A9J7G3I2_CRIGR Isoform 1 of PWWP domain-containing DNA repair factor 3A isoform X1 OS=Cricetulus griseus OX=10029 GN=Pwwp3a PE=3 SV=1 CANONICAL=A0A9J7G3I2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2/entry#A0A9J7JQE9-1", "sequence": { "sequence": "MCPGDRTQGLVHITASQNEVPAAPLEELTYRRSLRVALDLLNERTNLSPESHLMKDETTLSQKEKPHADMASWIPSAPSLSFHGEDGEDVAAQRISKSRWEYVPQSLSGLSASEEDPRCKVDRKTGLSKNGTPRAALLSPTGDGSRDSSGSRLDRGQEDTTSKRRRDLGEKPTRRHKTESRLSKGESVVENEGQASSCVTPASPRLLSQTWEEDPCAGVKGFDRVVPSGSSRLLPASERGRRHPTKRPRLDGGQNPQARQLGTGTVGAVPSLRSWSGEAMVLRSAGDNDKPEEADPVSSEESTGFKSIHSLLEDEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHTLLERAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISHPVRKSIQQDVLGTRFPQLGKGDAEEPVGDSRPGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSGQYVTCVETYLEDEAQLDEVVEYLQGICRDMDGEVPARGSGDRIRFVLDVLLPEAIICAISAVESVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR", "length": 635, "header": "tr|A0A9J7JQE9-1|A0A9J7JQE9_CRIGR Computationally mapped isoform of PWWP domain-containing DNA repair factor 3A isoform X3 OS=Cricetulus griseus OX=10029 GN=Pwwp3a PE=3 SV=1 CANONICAL=A0A9J7G3I2-1" }, "locus": {} }, { "isoform_ac": "G3HF72-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2/entry#G3HF72-1", "sequence": { "sequence": "MTDAKYVLCRWEKRLWPAKVLAITETSVKNRRKKELFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPAAPLEELTYRRSLRVALDLLNERTNLSPESHLMKDETTLSQKEKPHADMASWIPSAPSLSFHGEDGEDVAAQRISKSRWEYVPQSLSGLSASEEDPRCKVDRKTGLSKNGTPRAALLSPTGDGSRDSSGSRLDRGQEDTTSKRRRDLGEKPTRRHKTESRLSKGESVVENEGQASSCVTPASPRLLSQTWEEDPCAGVKGFDRVVPSGSSRLLPASERGRRHPTKRPRLDGGQNPQARQLGTGTVGAVPSLRSWSGEAMVLRSAGDNDKPEEDPVSSEESTGFKSIHSLLEDEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHTLLERAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISHPVRKSIQQDVLGTRFPQLGKGDAEEPVGDSRPGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSGQYVTCVETYLEDEAQLDEVVEYLQGICRDMDGEVPARGSGDRIRFVLDVLLPEAIICAISAVESVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR", "length": 691, "header": "tr|G3HF72-1|A0A9J7G3I2_CRIGR Computationally mapped isoform of PWWP domain-containing DNA repair factor 3A isoform X1 OS=Cricetulus griseus OX=10029 GN=Pwwp3a PE=3 SV=1 CANONICAL=A0A9J7G3I2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 257, "start_aa": "Thr", "end_pos": 257, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr257", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HF72", "url": "https://www.uniprot.org/uniprotkb/G3HF72" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HF72", "url": "https://www.uniprot.org/uniprotkb/G3HF72" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766402", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766402", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B1H224-1", "protein_name": "PWWP domain-containing DNA repair factor 3A", "gene_name": "Pwwp3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTDAKYVLCRWEKRLWPAKVLARTETSAKNKRKKEFFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERTSLSPESHPVENGSTPSQKGKPDADMASQVSSAPSPSFLSEDDQAVAAQCASKRRWECSPKSLSPLSASEEDLRCKVDPKTGLSESGALGTEVPAPTGDESQNGSGSQLDHGQESTTKKRQRNSGEKPARRGKAESGLSKGDSVAESGGQASSCVALASPRLPSQTWEGDPCAGVEGCDPVESSGNIRPLLDSERSKGRLTKRPRLDGGRNPLPRHLGTRTVGAVPSRRSCSGEVTTLRRAGDSDRPEEADPMSSEESTGFKSVHSLLEEEEEEEEEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQLGKGDPEEPMGDSRLGQWRPCRKVLPDRSRAARDKANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSNQYVTCMETYLEDEAQLDEVVEYLQGVCRDMDGEMPARGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYLRGPTLSYREKEIFDNELLEERNRRRR", "length": 698 }, "evidence": [ { "id": "A0A9J7G3I2", "url": "https://omabrowser.org/oma/group/A0A9J7G3I2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S6R2-1", "protein_name": "PWWP domain containing 3A, DNA repair factor", "gene_name": "PWWP3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTDAKYVLCKWKERLWPAKVLAGTEKSAKNKRKKNIFLNVQILSLDKKIKVMNKRAKILEKSHIESIASSLASESAVLAAPLEELAYRRALRVALDVLNERSYLQEESTSREERATVSPSEKPAEPAPSPYGPSPTPSLLEDALGCRRAQRRERLHQRLSGPTPLEKDPTCQVDHKDGLGRGGCPPAPALSSADGGPRRSRENWTTPSKRGRSPAQEASFSQNRLLVSEENKALCSPPRAGEEGTLGSPATLLSPGPVAYPHARSPDTRSPDGSTVRLGPAEDFGNDHLLDEARQSSEESVELNSVRSILEEDEEDEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKQAFLDEAKEDFGQAIGWCVSLITDYRVRLGCGSFTGSFLEYYAADISYPVRKSIQQDVQGTRFPQLSRGDLEEPTVGGPKGRRQACRKVLPDRSRAARDRANQRLVEYIVKARGAEGHLRDILKNRRPSRWLKTFLSSGQHVTCVETYLEDDEQLDLVVKYLQGLCQEAGNRALAHTGADRIRFVLDVLLPEAIICAISAVDSVDYKTAEEKYIRGPSLSYREKEIFDNQLLEERNRRC", "length": 631 }, "evidence": [ { "id": "A0A9J7G3I2", "url": "https://omabrowser.org/oma/group/A0A9J7G3I2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q08DK9-1", "protein_name": "PWWP domain-containing DNA repair factor 3A", "gene_name": "PWWP3A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTDAKYVLCRWKKRLWPAKVLAGTEKSAKNKRKKGYFLNVQILSLDKKIKVKSAEAKVLRKVHIEDIASSLASQDGTPAAPLEELTYRRSLRVALDVLNERQGSSSREGTTPRPPRVKPMEPASWPPKPSLSPSFLEDTAGSPGPTRRERMSQRLSGLPAGEEDLEYGVDHKEGLKRSGGLDAPAMCSASGGAQDREASRKQQADWMTPLGKQGRNPAQGPHSGQRVAPSSEGAGQEDGETGAGPAALCSPPGGRDLSPLDGCPAEHLGLDSGQRPRAHMSPHSPAQLGPAEEAADTRPLEEARPLSEEFMEPSAVNSLLEEDEDDEEPPRILLYHEPRSFEVGMLVWHKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPRGRGISVLLRRLKHFDCKEKQALLDEAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISSPVRKSIQQDVQGTRFPQLSGGDPEEPVAGSPQGRRPAYRKVLPDRSRAARDRANQKLVEYIVKARGAESHLRAILRNRKPSRWLKTFLSSGQYMTCVETYLEDEEQLDLVVKYLQGVYKQAGCQLLARGHGDGIRFILDVLLPEAIICAISAVDAVDYKTAEEKYIRGPALSSREKEIFDNQLLEERNRRC", "length": 641 }, "evidence": [ { "id": "A0A9J7G3I2", "url": "https://omabrowser.org/oma/group/A0A9J7G3I2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2TAK8-1", "protein_name": "PWWP domain-containing DNA repair factor 3A", "gene_name": "PWWP3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADAKYVLCRWEKRLWPAKVLARTATSTKNKRRKEYFLAVQILSLEEKIKVKSTEVEILEKSQIEAIASSLASQNEVPAAPLEELAYRRSLRVALDVLSEGSIWSQESSAGTGRADRSLRGKPMEHVSSPCDSNSSSLPRGDVLGSSRPHRRRPCVQQSLSSSFTCEKDPECKVDHKKGLRKSENPRGPLVLPAGGGAQDESGSRIHHKNWTLASKRGGNSAQKASLCLNGSSLSEDDTERDMGSKGGSWAAPSLPSGVREDDPCANAEGHDPGLPLGSLTAPPAPEPSACSEPGECPAKKRPRLDGSQRPPAVQLEPMAAGAAPSPGPGPGPRESVTPRSTARLGPPPSHASADATRCLPCPDSQKLEKECQSSEESMGSNSMRSILEEDEEDEEPPRVLLYHEPRSFEVGMLVWHKHKKYPFWPAVVKSVRQRDKKASVLYIEGHMNPKMKGFTVSLKSLKHFDCKEKQTLLNQAREDFNQDIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTKLPQLSKGSPEEPVVGCPLGQRQPCRKMLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILKSRKPSRWLQTFLSSSQYVTCVETYLEDEGQLDLVVKYLQGVYQEVGAKVLQRTNGDRIRFILDVLLPEAIICAISAVDEVDYKTAEEKYIKGPSLSYREKEIFDNQLLEERNRRRR", "length": 710 }, "evidence": [ { "id": "A0A9J7G3I2", "url": "https://omabrowser.org/oma/group/A0A9J7G3I2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6DID5-1", "protein_name": "PWWP domain-containing DNA repair factor 3A", "gene_name": "Pwwp3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTDAKYVLCRWGKRLWPAKVLARTETSAKNKKKKEFFLDVQILSLKEKIQVKSSAVEALQKSHIENIAAFLASQNEVPATPLEELTYRRSLRVALDVLNERTSLSPESHPIEDGITLSQKEKTDADVASQVSSAPSPSLLGEDGQAVVAQCASKRRSEYSSKSLLPSSALEDHLRCQVGPKTGLSESGAGDKSQDDSGLQLDHGQESTTKKRQRNLGEKPTRRRRSESGLSKGESVLKSQGQASSCVALASPRPPSQTRDEEPCAGVKGCDWVKSSGNIRPLSASERSRGCPTKRPRLDGGQNPPTRQLGTRTVGAAPCPRSCSGEVTMLCSAGAGDKPEEDPVSSEESTGFKSTHSLLEEEEEEEEEPPRILLYHEPRSFEVGMLVWLKYQKYPFWPAVVKSVRRRDKKASVLFIEGNMNPKGRGITVSLRRLKHFDCKEKHALLDRAKEDFAQAIGWCVSLITDYRVRLGCGSFAGSFLEYYAADISYPVRKSIQQDVLGTRFPQLGKGDPEEPVGDSQLGQWRPCRKVLPDRSRAARDRANQKLVEYIVKAKGAESHLRAILHSRKPSRWLKTFLSSSQCVTCMETYLEDEAQLDEVVEYLQGVCRDMDGQVPERGSGDRIRFILDVLLPEAIICAISAVEAVDYKTAEQKYIRGPTLSYREKEIFDNELLEERNRRRR", "length": 682 }, "evidence": [ { "id": "A0A9J7G3I2", "url": "https://omabrowser.org/oma/group/A0A9J7G3I2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleosome binding", "id": "GO:0031491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031491", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G3I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2" }, { "id": "PF20884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MUM1-like PWWP", "eco_id": "ECO_0000259", "start_pos": 391, "end_pos": 470, "start_aa": "Phe", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G3I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3I2" }, { "id": "PF20887", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20887" }, { "id": "PF20886", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 100, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 257 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 187, "end_pos": 189 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G405-1", "uniprot_ac": "A0A9J7G405", "uniprot_id": "A0A9J7G405_CRIGR", "mass": { "chemical_mass": 59840.0, "monoisotopic_mass": 59840.0 }, "refseq": { "ac": "XP_027275712", "name": "YTH domain-containing family protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275712" }, "gene_names": [ { "name": "Ythdf1", "type": "recommended", "evidence": [ { "id": "A0A9J7G405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405" } ] }, { "name": "Ythdf1", "type": "synonym", "evidence": [ { "id": "XP_027275712", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275712" } ] } ], "protein_names": [ { "name": "YTH domain-containing family protein", "type": "recommended", "evidence": [ { "id": "A0A9J7G405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405/entry#names_and_taxonomy" } ] }, { "name": "YTH domain-containing family protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027275712", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275712" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275712", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275712" } ] }, { "annotation": "Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.", "evidence": [ { "database": "UniProtKB", "id": "G3HGX9", "url": "https://www.uniprot.org/uniprotkb/G3HGX9#function" }, { "database": "UniProtKB", "id": "RU369095", "url": "https://www.uniprot.org/uniprotkb/RU369095#function" }, { "database": "UniProtKB", "id": "A0A9J7G405", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G405", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ythdf1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405", "locus": {} } ], "crossref": [ { "id": "A0A9J7G405", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G405", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21134", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21134", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766305", "url": "https://www.ncbi.nlm.nih.gov/gene/100766305", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045168", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045168", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766305", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766305", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G405", "url": "https://www.orthodb.org/?gene=A0A9J7G405", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12357:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12357:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04146", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04146", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275712", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275712", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G405", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G405-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HGX9", "url": "https://www.uniprot.org/uniprotkb/G3HGX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HGX9-1", "url": "https://www.uniprot.org/uniprotkb/G3HGX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTLSTDCHSRNVSSFTSLMLHFQRLKRNTMESNSYPSMSDPYLSSYYPPSIGFPYSLSEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQTGFHSDTLNKAPGMNSLEQGMVGLKIGDVTTSAVKTVGSVVNSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKAKSGPIVGGALPPPPIKHNMDIGTWDNKGPVSKASAPQQTPSPQAAPQPQQVAQPLPVQPPPLVQPQYQSPQQPLQPRWVAPRNRNAAFGQSGVANSDSNSVGNAQPTSAPSVESHPVLEKLKAAHSYNPKEFDWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAFRSMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEEVVRKERQNRNKQ", "length": 547, "header": "tr|A0A9J7G405-1|A0A9J7G405_CRIGR Isoform 1 of YTH domain-containing family protein OS=Cricetulus griseus OX=10029 GN=Ythdf1 PE=3 SV=1 CANONICAL=A0A9J7G405-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G405-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405/entry#A0A9J7G405-1", "sequence": { "sequence": "MSTLSTDCHSRNVSSFTSLMLHFQRLKRNTMESNSYPSMSDPYLSSYYPPSIGFPYSLSEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQTGFHSDTLNKAPGMNSLEQGMVGLKIGDVTTSAVKTVGSVVNSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKAKSGPIVGGALPPPPIKHNMDIGTWDNKGPVSKASAPQQTPSPQAAPQPQQVAQPLPVQPPPLVQPQYQSPQQPLQPRWVAPRNRNAAFGQSGVANSDSNSVGNAQPTSAPSVESHPVLEKLKAAHSYNPKEFDWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAFRSMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEEVVRKERQNRNKQ", "length": 547, "header": "tr|A0A9J7G405-1|A0A9J7G405_CRIGR Isoform 1 of YTH domain-containing family protein OS=Cricetulus griseus OX=10029 GN=Ythdf1 PE=3 SV=1 CANONICAL=A0A9J7G405-1" }, "locus": {} }, { "isoform_ac": "G3HGX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405/entry#G3HGX9-1", "sequence": { "sequence": "MSDPYLSSYYPPSIGFPYSLSEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQTGFHSDTLNKAPGMNSLEQGMVGLKIGDVTTSAVKTVGSVVNSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKAKSGPIVGGALPPPPIKHNMDIGTWDNKGPVSKASAPQQTPSPQAAPQPQQVAQPLPVQPPPLVQPQYQSPQQPLQPRWVAPRNRNAAFGQSGVANSDSNSVGNAQPTSAPSVESHPVLEKLKAAHSYNPKEFDWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDGAFRSMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEEVVRKERQNRNKQ", "length": 509, "header": "tr|G3HGX9-1|A0A9J7G405_CRIGR Computationally mapped isoform of YTH domain-containing family protein OS=Cricetulus griseus OX=10029 GN=Ythdf1 PE=3 SV=1 CANONICAL=A0A9J7G405-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HGX9", "url": "https://www.uniprot.org/uniprotkb/G3HGX9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HGX9", "url": "https://www.uniprot.org/uniprotkb/G3HGX9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766305", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766305", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G405", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405" } ], "pmid": "" }, { "name": "N6-methyladenosine-containing RNA reader activity", "id": "GO:1990247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990247", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G405", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G405", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G405", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA destabilization", "id": "GO:0061157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061157", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G405", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G405", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G405" }, { "id": "PS50882", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50882" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YTH", "eco_id": "ECO_0000259", "start_pos": 377, "end_pos": 511, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 429, "end_pos": 431 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G456-1", "uniprot_ac": "A0A9J7G456", "uniprot_id": "A0A9J7G456_CRIGR", "mass": { "chemical_mass": 55127.0, "monoisotopic_mass": 55127.0 }, "refseq": { "ac": "XP_027275925", "name": "RNA-binding protein 45 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275925" }, "gene_names": [ { "name": "Rbm45", "type": "recommended", "evidence": [ { "id": "A0A9J7G456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456" } ] }, { "name": "Rbm45", "type": "synonym", "evidence": [ { "id": "XP_027275925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275925" } ] } ], "protein_names": [ { "name": "RNA-binding protein 45", "type": "recommended", "evidence": [ { "id": "A0A9J7G456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456/entry#names_and_taxonomy" } ] }, { "name": "Developmentally-regulated RNA-binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7G456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding motif protein 45", "type": "synonym", "evidence": [ { "id": "A0A9J7G456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456/entry#names_and_taxonomy" } ] }, { "name": "RNA-binding protein 45 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027275925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275925" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275925" } ] }, { "annotation": "RNA-binding protein with binding specificity for poly(C). May play an important role in neural development.", "evidence": [ { "database": "UniProtKB", "id": "G3HAC0", "url": "https://www.uniprot.org/uniprotkb/G3HAC0#function" }, { "database": "UniProtKB", "id": "ARBA00057759", "url": "https://www.uniprot.org/uniprotkb/ARBA00057759#function" }, { "database": "UniProtKB", "id": "A0A9J7G456", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456#function" }, { "database": "UniProtKB", "id": "A0A9J7G489", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G489#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G456", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rbm45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456", "locus": {} } ], "crossref": [ { "id": "A0A9J7G456", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G456", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12366", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12366", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12367", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12367", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12368", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12368", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12369", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12369", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764756", "url": "https://www.ncbi.nlm.nih.gov/gene/100764756", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764756", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764756", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MIPKTYT", "url": "https://omabrowser.org/oma/group/MIPKTYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G456", "url": "https://www.orthodb.org/?gene=A0A9J7G456", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G489", "url": "https://www.orthodb.org/?gene=A0A9J7G489", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HAC0", "url": "https://www.orthodb.org/?gene=G3HAC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275925", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G456", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G456-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G489", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G489", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G489-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G489-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HAC0", "url": "https://www.uniprot.org/uniprotkb/G3HAC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HAC0-1", "url": "https://www.uniprot.org/uniprotkb/G3HAC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDSSSSAGSGGFRPGVDSLDEPPNSRIFLVISKYTSESVLRERFSPFGDIQDIWVVRDKHTKESKGVAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVLHWGAYVRVCEVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRALLAEPKNKVPESPEQDYYSSMRQEALGHEPRVNLFPFVGEQQSEFSSFDKSDSRSQEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAVYAKYKLHGFQYPPGNRIGVSFLDDGSNSADLIRKMATQMVASQLASMVWSNPSQQQQFLQFGGSSGSQLPQIQTDVVLPSCKKKAPPETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYVKYADRMSANDAISTLHGKILNGVRLKVMLADSPREEPKKRQRTY", "length": 489, "header": "tr|A0A9J7G456-1|A0A9J7G456_CRIGR Isoform 1 of RNA-binding protein 45 OS=Cricetulus griseus OX=10029 GN=Rbm45 PE=4 SV=1 CANONICAL=A0A9J7G456-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G456-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456/entry#A0A9J7G456-1", "sequence": { "sequence": "MEDSSSSAGSGGFRPGVDSLDEPPNSRIFLVISKYTSESVLRERFSPFGDIQDIWVVRDKHTKESKGVAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVLHWGAYVRVCEVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRALLAEPKNKVPESPEQDYYSSMRQEALGHEPRVNLFPFVGEQQSEFSSFDKSDSRSQEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAVYAKYKLHGFQYPPGNRIGVSFLDDGSNSADLIRKMATQMVASQLASMVWSNPSQQQQFLQFGGSSGSQLPQIQTDVVLPSCKKKAPPETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYVKYADRMSANDAISTLHGKILNGVRLKVMLADSPREEPKKRQRTY", "length": 489, "header": "tr|A0A9J7G456-1|A0A9J7G456_CRIGR Isoform 1 of RNA-binding protein 45 OS=Cricetulus griseus OX=10029 GN=Rbm45 PE=4 SV=1 CANONICAL=A0A9J7G456-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G489-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456/entry#A0A9J7G489-1", "sequence": { "sequence": "MEDSSSSAGSGGFRPGVDSLDEPPNSRIFLVISKYTSESVLRERFSPFGDIQDIWVVRDKHTKESKGVAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVLHWGAYVRVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRALLAEPKNKVPESPEQDYYSSMRQEALGHEPRVNLFPFVGEQQSEFSSFDKSDSRSQEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAVYAKYKLHGFQYPPGNRIGVSFLDDGSNSADLIRKMATQMVASQLASMVWSNPSQQQQFLQFGGSSGSQLPQIQTDVVLPSCKKKAPPETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYVKYADRMSANDAISTLHGKILNGVRLKVMLADSPREEPKKRQRTY", "length": 486, "header": "tr|A0A9J7G489-1|A0A9J7G489_CRIGR Computationally mapped isoform of RNA-binding protein 45 OS=Cricetulus griseus OX=10029 GN=Rbm45 PE=4 SV=1 CANONICAL=A0A9J7G456-1" }, "locus": {} }, { "isoform_ac": "G3HAC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456/entry#G3HAC0-1", "sequence": { "sequence": "MEDSSSSAGSGGFRPGVDSLDEPPNSRIFLVISKYTSESVLRERFSPFGDIQDIWVVRDKHTKESKGVAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRALLAEPKNKVPESPEQDYYSSMRQEALGHEPRVNLFPFVGEQQSEFSSFDKSDSRSQEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAVYAKYKLHGFQYPPGNRIGVSFLDDGSNSADLIRKMATQMVASQLASMVWSNPSQQQQFLQFGGSSGSQLPQIQTDVVLPSCKKKAPPETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYVKYADRMSANDAISTLHGKILNGVRLKVMLADSPREEPKKRQRTY", "length": 477, "header": "tr|G3HAC0-1|A0A9J7G456_CRIGR Computationally mapped isoform of RNA-binding protein 45 OS=Cricetulus griseus OX=10029 GN=Rbm45 PE=4 SV=1 CANONICAL=A0A9J7G456-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HAC0", "url": "https://www.uniprot.org/uniprotkb/G3HAC0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HAC0", "url": "https://www.uniprot.org/uniprotkb/G3HAC0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764756", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764756", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZY00-1", "protein_name": "RNA binding motif protein 45", "gene_name": "RBM45", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLSPRRKEAGGSSSPGPEQSQRSTTAREPSGSSAMEESSGFRLSAECLDEPPNSRVFVVLGKDAGEALIRERFAPFGDIQNIWLLRDKRTNESRGIAFIKFARSSQACRAMEEMHGRSLVPDTKPIKVFIAQSRASGSHRDVEDEELTRIFVMIPKTYTEEDLREKFKMYGDIEYCSIIKNKTTGESKGLGYVRYLKPSQAARAIEECDRSYRAILAEPKNKSSESFEHEYYSNNARQEPRGNVFPFCAQPEFCSFEKNETRIQESVSKRLSVVSRLPFIQEQLFALFDLVPGLEYCDVQRDPHTNNGYAVIQYSTAASAIYAKYKLHGFEYPPGNRLTVIFLEDGNDSSDLIRKMATQLVTAHMTSVLRNNNAVVQPYRTPPQAFGGASGSPLLQPQTDAMLPPPKKKMPPDTTVKERLFVLFHPHPLPVTILEDVFCRFGNLIKVYLVAGKNVAYAKFADRASASEAITALHGKIVNGVRLKVRLADSPTEESNKRQRTY", "length": 502 }, "evidence": [ { "id": "A0A9J7G456", "url": "https://omabrowser.org/oma/group/A0A9J7G456/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B0S522-1", "protein_name": "RNA-binding protein 45", "gene_name": "rbm45", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDDSNRPSSYLDEPPNSRLFLVTSKSITEDTIRESFASFGEIQDIWVVKDKQTKESKGVAFIKFAKSSQACTAMEEMHGRCLAEGTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKTFTEDDLKETFKVYGDIEYAIIIRNKTTGDSKGLGYVRFHKPSQAAKAVENCDKTFRAIIAEPRTKNSSADNDYFSNPRTTEHSTSELGSSSYAFAQESSSYSAAESYSSDIITRCLMVSSRVSVSQEQIYSLFDLIPGLDYCEIQRDQYGFSKGQVVVRYSNLGSAVYAKEKLNGFEYPPGNRLSVSFVDDGEDRTSPVGKMAMQLVAAQMMSMVWNGPSGSQLMKTSAGYTAPPVPQKARLQTDANLPAPKKLLALDSVVKERLFVIFNPSPLPVEVLEDVFCRFGSLIEVYLVPGRNVGYIKYADRRSAHDAIDTMHGKVVNGVKMKVMLADPPKEESHKRQRTY", "length": 467 }, "evidence": [ { "id": "A0A9J7G456", "url": "https://omabrowser.org/oma/group/A0A9J7G456/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BHN5-1", "protein_name": "RNA-binding protein 45", "gene_name": "Rbm45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDAGGLGGSGGFRPGVDSLDEPPNSRIFLVISKHTSELVLRERFSPFGDIQDIWVVRDKHTKESKGVAFVKFARSSQACRAMEEMHGQCLGPSDTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRALLAEPKNKVSGSPEQDDYSSGRQEALGQEPRANLFPFVGEQQSEFSTFDKNDSRGQEAVSKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVPRDPYSNYGHGVVQYFNVASAIYAKYKLHGFQYPPGNRIVVSFLDDGSNMTELIRKMATQMVAAQLASMVWSTTSQQQFLQYGGNAASQAPQIQTDVVLPSCKKKAPPETPVKERLFVVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYVKYADRKSANEAITTLHGKILNGVRLKVMLADSPREESKKRQRTY", "length": 476 }, "evidence": [ { "id": "A0A9J7G456", "url": "https://omabrowser.org/oma/group/A0A9J7G456/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CFD1-1", "protein_name": "RNA-binding protein 45", "gene_name": "Rbm45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDAGSSGGSGGFRPGVDSLDEPPNSRIFLVISKYTSESVLREHFSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSVIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRALLAEPKNKVLESPEQDYYSSVRQETLGHEPRGNLFPFVGEQQSEFSTFDKNDSRGQEAISKRLSVASRVPFTEEQLFSIFDIVPGLEYCEVHRDPYLNYGHGVVQYFNVASAVYAQYKLHGFQYPPGNRIAVSFLDDGSNSADLIRKMATQMVAAQLASTVWSNPSHQQFLQFGGSAGSQVPQIQTDVVLPSCRKKAPPETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYVKYADRMSANDAITTLHGKILNGVRLKVMLADSPREVSKKRQRTY", "length": 476 }, "evidence": [ { "id": "A0A9J7G456", "url": "https://omabrowser.org/oma/group/A0A9J7G456/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IUH3-1", "protein_name": "RNA-binding protein 45", "gene_name": "RBM45", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFVGEQQSEFSSFDKNDSRGQEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYAKYKLHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQFGGSSGSQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY", "length": 476 }, "evidence": [ { "id": "A0A9J7G456", "url": "https://omabrowser.org/oma/group/A0A9J7G456/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VZE4-1", "protein_name": "RRM domain-containing protein", "gene_name": "cg1316", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDYRSQSRSGGGRGGQEYSNDDDPPMSRLFIICNKAHTEEDFREAFSPYGEIEDIWVVKDKHTQENKGIAYVKFSKTSDAAKAQEEMNGKTIGKMDRTLKVLVAANRNQGSNKSENEQEKYVRLFIVIPKTATEEDIREEFSQWGDVESVTIVKEKNNGNPKGFGYVRFTKFYYAAVAFENCSAKYKAVFAEPKGSTRTQRDQYGRPSEDNPLYSSSGRGNSNFNGGGSSSGGGGSNSYNNDWNVSQNNDMAAFLRMQNVPVAQPSCLEVNVSNCVNQDQLWRLFDIIPGLDYCQIMREHGPRTNEALVVYDNPEAAIYAKDKLHGLEYPMGERIIVKVNGMSSARMDTSFIDKRTKKDAICNVPLPPTQPLASPDDQVAQRLFIVLSANLPHSILKNIFSCWSGLIDVYLLPNKNCGYVKYAEVESAQLAIRTLNGAEICGTKIKVMEAEERSGSDGDDGGRKRLRRN", "length": 470 }, "evidence": [ { "id": "A0A9J7G456", "url": "https://omabrowser.org/oma/group/A0A9J7G456/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G456", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G456", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G456", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G456", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G456", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G456", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G456" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 101, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G443-1", "uniprot_ac": "A0A9J7G443", "uniprot_id": "A0A9J7G443_CRIGR", "mass": { "chemical_mass": 36478.0, "monoisotopic_mass": 36478.0 }, "refseq": { "ac": "XP_007643379", "name": "serine/threonine-protein kinase Nek7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643379" }, "gene_names": [ { "name": "Nek7", "type": "recommended", "evidence": [ { "id": "A0A9J7G443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ] }, { "name": "Nek7", "type": "synonym", "evidence": [ { "id": "XP_007643379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643379" } ] } ], "protein_names": [ { "name": "NEK6-subfamily protein kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7G443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.34", "type": "synonym", "evidence": [ { "id": "A0A9J7G443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase Nek7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007643379", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643379" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614079.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007643379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643379" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nek7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443", "locus": {} } ], "crossref": [ { "id": "cd08224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765727", "url": "https://www.ncbi.nlm.nih.gov/gene/100765727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765727", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765727", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEQMNAH", "url": "https://omabrowser.org/oma/group/SEQMNAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G443", "url": "https://www.orthodb.org/?gene=A0A9J7G443", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HM24", "url": "https://www.orthodb.org/?gene=G3HM24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43289:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43289:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007643379", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643379", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G443-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2Q8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HM24", "url": "https://www.uniprot.org/uniprotkb/G3HM24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HM24-1", "url": "https://www.uniprot.org/uniprotkb/G3HM24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEQPQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYESPLKLLCAYISFTGSVLQMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACTANS", "length": 320, "header": "tr|A0A9J7G443-1|A0A9J7G443_CRIGR Isoform 1 of NEK6-subfamily protein kinase OS=Cricetulus griseus OX=10029 GN=Nek7 PE=3 SV=1 CANONICAL=A0A9J7G443-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G443-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443/entry#A0A9J7G443-1", "sequence": { "sequence": "MDEQPQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYESPLKLLCAYISFTGSVLQMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACTANS", "length": 320, "header": "tr|A0A9J7G443-1|A0A9J7G443_CRIGR Isoform 1 of NEK6-subfamily protein kinase OS=Cricetulus griseus OX=10029 GN=Nek7 PE=3 SV=1 CANONICAL=A0A9J7G443-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443/entry#A0A9J7H2Q8-1", "sequence": { "sequence": "MDEQPQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVFFRFLNPEQNCDLTGS", "length": 213, "header": "tr|A0A9J7H2Q8-1|A0A9J7H2Q8_CRIGR Computationally mapped isoform of NEK6-subfamily protein kinase OS=Cricetulus griseus OX=10029 GN=Nek7 PE=3 SV=1 CANONICAL=A0A9J7G443-1" }, "locus": {} }, { "isoform_ac": "G3HM24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443/entry#G3HM24-1", "sequence": { "sequence": "MDEQPQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACTANS", "length": 302, "header": "tr|G3HM24-1|A0A9J7G443_CRIGR Computationally mapped isoform of NEK6-subfamily protein kinase OS=Cricetulus griseus OX=10029 GN=Nek7 PE=3 SV=1 CANONICAL=A0A9J7G443-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HM24", "url": "https://www.uniprot.org/uniprotkb/G3HM24" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HM24", "url": "https://www.uniprot.org/uniprotkb/G3HM24" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765727", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765727", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SPG3-1", "protein_name": "NEK6-subfamily protein kinase", "gene_name": "NEK7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDITYVYDVAKRMHTCTASS", "length": 302 }, "evidence": [ { "id": "A0A9J7G443", "url": "https://omabrowser.org/oma/group/A0A9J7G443/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9TMM9-1", "protein_name": "NEK6-subfamily protein kinase", "gene_name": "NEK7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFPRQEYWSGLPFPSPGDLLDPETEPASPVLQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDITYVYDVAKRMHACTASA", "length": 316 }, "evidence": [ { "id": "A0A9J7G443", "url": "https://omabrowser.org/oma/group/A0A9J7G443/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZBE5-1", "protein_name": "Serine/threonine-protein kinase Nek7", "gene_name": "Nek7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDEQPQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACTASS", "length": 302 }, "evidence": [ { "id": "A0A9J7G443", "url": "https://omabrowser.org/oma/group/A0A9J7G443/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6DEH7-1", "protein_name": "NEK6-subfamily protein kinase", "gene_name": "nek7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDAQSQGQQPPVPVYQPQKIDMGYNSLANFAIEKKIGRGQFSEVYRATYVLDHTIVALKKIQIFDLMDAKARQDCIKEIDLLKQLNHPNVIKYHASFIEENELNIVLELADAGDLSQMIRHFKKQRRLIPEKTVWKYFVQLCSALEHMHSRRIMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSQELRKLVDMCINPDPEKRPDITYVYSMAKHMHGRIAN", "length": 297 }, "evidence": [ { "id": "A0A9J7G443", "url": "https://omabrowser.org/oma/group/A0A9J7G443/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8TDX7-1", "protein_name": "Serine/threonine-protein kinase Nek7", "gene_name": "NEK7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEQSQGMQGPPVPQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRMHACTASS", "length": 302 }, "evidence": [ { "id": "A0A9J7G443", "url": "https://omabrowser.org/oma/group/A0A9J7G443/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ES74-1", "protein_name": "Serine/threonine-protein kinase Nek7", "gene_name": "Nek7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEQSQGMQGPPVTQFQPQKALRPDMGYNTLANFRIEKKIGRGQFSEVYRASCLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALDHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNICINPDPEKRPDIAYVYDVAKRMHACTAST", "length": 302 }, "evidence": [ { "id": "A0A9J7G443", "url": "https://omabrowser.org/oma/group/A0A9J7G443/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" }, { "name": "molecular function activator activity", "id": "GO:0140677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of mitotic cell cycle", "id": "GO:0007346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007346", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" }, { "name": "positive regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900227", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" }, { "name": "cellular response to potassium ion", "id": "GO:0035865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035865", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G443", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G443", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G443" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 317, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.34", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.34", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.34" }, { "id": "2.7.11.34", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.34" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GAN6-1", "uniprot_ac": "A0A9J7GAN6", "uniprot_id": "A0A9J7GAN6_CRIGR", "mass": { "chemical_mass": 83792.0, "monoisotopic_mass": 83792.0 }, "refseq": { "ac": "XP_027280674", "name": "FLYWCH-type zinc finger-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280674" }, "gene_names": [ { "name": "Flywch1", "type": "recommended", "evidence": [ { "id": "A0A9J7GAN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6" } ] }, { "name": "Flywch1", "type": "synonym", "evidence": [ { "id": "XP_027280674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280674" } ] } ], "protein_names": [ { "name": "FLYWCH-type zinc finger-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7GAN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6/entry#names_and_taxonomy" } ] }, { "name": "FLYWCH-type zinc finger-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027280674", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280674" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280674" } ] }, { "annotation": "Transcription cofactor. Negatively regulates transcription activation by catenin beta-1 CTNNB1, perhaps acting by competing with TCF4 for CTNNB1 binding. May play a role in DNA-damage response signaling. Binds specifically to DNA sequences at peri-centromeric chromatin loci.", "evidence": [ { "database": "UniProtKB", "id": "G3IFB3", "url": "https://www.uniprot.org/uniprotkb/G3IFB3#function" }, { "database": "UniProtKB", "id": "ARBA00056066", "url": "https://www.uniprot.org/uniprotkb/ARBA00056066#function" }, { "database": "UniProtKB", "id": "A0A9J7G9K6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K6#function" }, { "database": "UniProtKB", "id": "A0A9J7GAN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6#function" }, { "database": "UniProtKB", "id": "A0A9J7GE77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE77#function" }, { "database": "UniProtKB", "id": "A0A9J7H2W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2W4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Flywch1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6", "locus": {} } ], "crossref": [ { "id": "A0A9J7GAN6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GAN6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100772983", "url": "https://www.ncbi.nlm.nih.gov/gene/100772983", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772983", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772983", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9K6", "url": "https://www.orthodb.org/?gene=A0A9J7G9K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GAN6", "url": "https://www.orthodb.org/?gene=A0A9J7GAN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GE77", "url": "https://www.orthodb.org/?gene=A0A9J7GE77", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3IFB3", "url": "https://www.orthodb.org/?gene=G3IFB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31665", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31665", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31665:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31665:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04500", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04500", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280674", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280674", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G9K6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GE77", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GE77-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3IFB3", "url": "https://www.uniprot.org/uniprotkb/G3IFB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3IFB3-1", "url": "https://www.uniprot.org/uniprotkb/G3IFB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLPEPNEQESESVKAGQEPSLGARKPQEPSNLVKDKGGSKPTGAMALETSGPATLSSNTSQTLPAKKQGRIIHRKRSRVDAAAPQPLEFLKTQYGGRLLVHKSFLYKQEKAVGDKVYWKCRQHSELSCRGRAITRGFRVTVMRDHCHPPDEEGLQVRRQKEKPPSSDLPEGSEGQEEGVSLWLYPVEPEPTPQQSTETPEEDQGYRSLALQSLPPKKRPTPGVVRYRPLEFLKTCYGGTFLVHQSFLYKREKTVGSKVYWTCREHAVHGCRSRAITQGQRVTVMRSHCHSPDMEGLQARRQQEKTIKKIQARRIGAGDLEDCDDIEDTLLQGVDSLFYRRGKRTLTLSRSRSRSRSRKRAKKRKESFQEPPEQEDQDVDPRGPEFLRTPLGGSFLVYESFLYRREKVAGEKVYWTCRDQARMGCRSRAITQGRQVTVMRGHCHPPDLLGLETLRQREKRPGPTQWDGPEGPEFLKTPLGGSFLVYESFLYRREKATGNKVYWTCRDQARMGCRSRAITQGQRVMVMRRHCHPPDMGSLEALRQRENFPNLTNWEGPEPLQPLELLRTPLGGRFLVYESFLYRKEKAAGEKVYWMCRDQARLGCRSRAITQGRRVMVMRSHCHPPDLDGLEALRERDREQREREQEQEKEREQELERVREREREREREREREREREREQERRSSAAKKKKKKRKKKKSTKSTKSTKSTKSTKSTKRTSKKSKN", "length": 723, "header": "tr|A0A9J7GAN6-1|A0A9J7GAN6_CRIGR Isoform 1 of FLYWCH-type zinc finger-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Flywch1 PE=4 SV=1 CANONICAL=A0A9J7GAN6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G9K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6/entry#A0A9J7G9K6-1", "sequence": { "sequence": "MPLPEPNEQESESVKAGQEPSLGARKPQEPSNLVKDKGGSKPTGAMALETSGPATLSSNTSQTLPAKKQGRIIHRKRSRVDAAAPQPLEFLKTQYGGRLLVHKSFLYKQEKAVGDKVYWKCRQHSELSCRGRAITRGFRVTVMRDHCHPPDEEGLQVRRQKEKPPSSDLPEGSEGQEEGVSLWLYPVEPEPTPQQSTETPEEDQGYRSLALQSLPPKKRPTPGVVRYRPLEFLKTCYGGTFLVHQSFLYKREKTVGSKVYWTCREHAVHGCRSRAITQGQRVTVMRSHCHSPDMEGLQARRQQEKTIKKIQARRIGAGDLEDCDDIEDTLLQGVDSLFYRRGKRTLTLSRSRSRSRSRKRAKKRKESFQEPPEQEDQDVDPRGPEFLRTPLGGSFLVYESFLYRREKVAGEKVYWTCRDQARMGCRSRAITQGRQVTVMRGHCHPPDLLGLETLRQREKRPGPTQWDGPEGPEFLKTPLGGSFLVYESFLYRREKATGNKVYWTCRDQARMGCRSRAITQGQRVMVMRRHCHPPDMGSLEALRQRENFPNLTNWEGPEPLQPLELLRTPLGGRFLVYESFLYRKEKAAGEKVYWMCRDQARLGCRSRAITQGRRVMVMRSHCHPPDLDGLEALRERDREQREREQEQEKEREQELERVREREREREREREREREREREQERRSSAAKKKKKKRKKKKSTKSTKRTSKKSKN", "length": 711, "header": "tr|A0A9J7G9K6-1|A0A9J7G9K6_CRIGR Computationally mapped isoform of FLYWCH-type zinc finger-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Flywch1 PE=4 SV=1 CANONICAL=A0A9J7GAN6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6/entry#A0A9J7GAN6-1", "sequence": { "sequence": "MPLPEPNEQESESVKAGQEPSLGARKPQEPSNLVKDKGGSKPTGAMALETSGPATLSSNTSQTLPAKKQGRIIHRKRSRVDAAAPQPLEFLKTQYGGRLLVHKSFLYKQEKAVGDKVYWKCRQHSELSCRGRAITRGFRVTVMRDHCHPPDEEGLQVRRQKEKPPSSDLPEGSEGQEEGVSLWLYPVEPEPTPQQSTETPEEDQGYRSLALQSLPPKKRPTPGVVRYRPLEFLKTCYGGTFLVHQSFLYKREKTVGSKVYWTCREHAVHGCRSRAITQGQRVTVMRSHCHSPDMEGLQARRQQEKTIKKIQARRIGAGDLEDCDDIEDTLLQGVDSLFYRRGKRTLTLSRSRSRSRSRKRAKKRKESFQEPPEQEDQDVDPRGPEFLRTPLGGSFLVYESFLYRREKVAGEKVYWTCRDQARMGCRSRAITQGRQVTVMRGHCHPPDLLGLETLRQREKRPGPTQWDGPEGPEFLKTPLGGSFLVYESFLYRREKATGNKVYWTCRDQARMGCRSRAITQGQRVMVMRRHCHPPDMGSLEALRQRENFPNLTNWEGPEPLQPLELLRTPLGGRFLVYESFLYRKEKAAGEKVYWMCRDQARLGCRSRAITQGRRVMVMRSHCHPPDLDGLEALRERDREQREREQEQEKEREQELERVREREREREREREREREREREQERRSSAAKKKKKKRKKKKSTKSTKSTKSTKSTKSTKRTSKKSKN", "length": 723, "header": "tr|A0A9J7GAN6-1|A0A9J7GAN6_CRIGR Isoform 1 of FLYWCH-type zinc finger-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Flywch1 PE=4 SV=1 CANONICAL=A0A9J7GAN6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GE77-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6/entry#A0A9J7GE77-1", "sequence": { "sequence": "MPLPEPNEQESESVKAGQEPSLGARKPQEPSNLVKDKGGSKPTGAMALETSGPATLSSNTSQTLPAKKQGRIIHRKRSRVDAAAPQPLEFLKTQYGGRLLVHKSFLYKQEKAVGDKVYWKCRQHSELSCRGRAITRGFRVTVMRDHCHPPDEEGLQVRRQKEKPPSSDLPEGSEGQEEGVSLWLYPVEPEPTPQQSTETPEEDQGYRSLALQSLPPKKRPTPGVVRYRPLEFLKTCYGGTFLVHQSFLYKREKTVGSKVYWTCREHAVHGCRSRAITQGQRVTVMRSHCHSPDMEGLQARRQQEKTIKKIQARRIGAGDLEDCDDIEDTLLQGVDSLFYRRGKRTLTLSRSRSRSRSRKRAKKRKESFQEPPEQEDQDVDPRGPEFLRTPLGGSFLVYESFLYRREKVAGEKVYWTCRDQARMGCRSRAITQGRQVTVMRGHCHPPDLLGLETLRQREKRPGPTQWDGPEGPEFLKTPLGGSFLVYESFLYRREKATGNKVYWTCRDQARMGCRSRAITQGQRVMVMRRHCHPPDMGSLEALRQRENFPNLTNWEGPEPLQPLELLRTPLGGRFLVYESFLYRKEKAAGEKVYWMCRDQARLGCRSRAITQGRRVMVMRSHCHPPDLDGLEALRERDREQREREQEQEKEREQELERVREREREREREREREREREREQERRSSAAKKKKKKRKKKKSTKRTSKKSKN", "length": 708, "header": "tr|A0A9J7GE77-1|A0A9J7GE77_CRIGR Computationally mapped isoform of FLYWCH-type zinc finger-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Flywch1 PE=4 SV=1 CANONICAL=A0A9J7GAN6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6/entry#A0A9J7H2W4-1", "sequence": { "sequence": "MPLPEPNEQESESVKAGQEPSLGARKPQEPSNLVKDKGGSKPTGAMALETSGPATLSSNTSQTLPAKKQGRIIHRKRSRVDAAAPQPLEFLKTQYGGRLLVHKSFLYKQEKAVGDKVYWKCRQHSELSCRGRAITRGFRVTVMRDHCHPPDEEGLQVRRQKEKPPSSDLPEGSEGQEEGVSLWLYPVEPEPTPQQSTETPEEDQGYRSLALQSLPPKKRPTPGVVRYRPLEFLKTCYGGTFLVHQSFLYKREKTVGSKVYWTCREHAVHGCRSRAITQGQRVTVMRSHCHSPDMEGLQARRQQEKTIKKIQARRIGAGDLEDCDDIEDTLLQGVDSLFYRRGKRTLTLSRSRSRSRSRKRAKKRKESFQEPPEQEDQDVDPRGPEFLRTPLGGSFLVYESFLYRREKVAGEKVYWTCRDQARMGCRSRAITQGRQVTVMRGHCHPPDLLGLETLRQREKRPGPTQWDGPEGPEFLKTPLGGSFLVYESFLYRREKATGNKVYWTCRDQARMGCRSRAITQGQRVMVMRRHCHPPDMGSLEALRQRENFPNLTNWEGPEPLQPLELLRTPLGGRFLVYESFLYRKEKAAGEKVYWMCRDQARLGCRSRAITQGRRVMVMRSHCHPPDLDGLEALRERDREQREREQEQEKEREQELERVREREREREREREREREREREQERRSSAAKKKKKKRKKKKSTKSTKSTKSTKSTKRTSKKSKN", "length": 720, "header": "tr|A0A9J7H2W4-1|A0A9J7H2W4_CRIGR Computationally mapped isoform of FLYWCH-type zinc finger-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Flywch1 PE=4 SV=1 CANONICAL=A0A9J7GAN6-1" }, "locus": {} }, { "isoform_ac": "G3IFB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6/entry#G3IFB3-1", "sequence": { "sequence": "MPLPEPNEQESESVKAGQEPSLGARKPQEPSNLVKDKGGSKPTGAMALETSGPATLSSNTSQTLPAKKQGRIIHRKRSRVDAAAPQPLEFLKTQYGGRLLVHKSFLYKQEKAVGDKVYWKCRQHSELSCRGRAITRGFRVTVMRDHCHPPDEEGLQVRRQKEKPPSSDLPEGSEGQEEGVSLWLYPVEPEPTPQQSTETPEEDQGYRSLALQSLPPKKRPTPGVVRYRPLEFLKTCYGGTFLVHQSFLYKREKTVGSKVYWTCREHAVHGCRSRAITQGQRVTVMRSHCHSPDMEGLQARRQQEKTIKKIQARRIGAGDLEDCDDIEDTLLQGVDSLFYRRGKRTLTLSRSRSRSRSRKRAKKRKESFQEPPEQEDQDVDPRGPEFLRTPLGGSFLVYESFLYRREKVAGEKVYWTCRDQARMGCRSRAITQGRQVTVMRGHCHPPDLLGLETLRQREKRPGPTQWDGPEGPEFLKTPLGGSFLVYESFLYRREKATGNKVYWTCRDQARMGCRSRAITQGQRVMVMRRHCHPPDMGSLEALRQRENFPNLTNWEGPEPLQPLELLRTPLGGRFLVYESFLYRKEKAAGEKVYWMCRDQARLGCRSRAITQGRRVMVMRSHCHPPDLDGLEALRERDREQREREQEQEKEREQELERVREREREREREREREREREREQERRSSAAKKKKKKRKKKKSTKSTKSTKSTKRTSKKSKN", "length": 717, "header": "tr|G3IFB3-1|A0A9J7GAN6_CRIGR Computationally mapped isoform of FLYWCH-type zinc finger-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Flywch1 PE=4 SV=1 CANONICAL=A0A9J7GAN6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 192, "start_aa": "Thr", "end_pos": 192, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr192", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 221, "start_aa": "Thr", "end_pos": 221, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr221", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 464, "start_aa": "Thr", "end_pos": 464, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr464", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3IFB3", "url": "https://www.uniprot.org/uniprotkb/G3IFB3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3IFB3", "url": "https://www.uniprot.org/uniprotkb/G3IFB3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772983", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772983", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAN6", "url": 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"name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 135, 192, 221, 464 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 550, "end_pos": 552 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", 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"type": "synonym", "evidence": [ { "id": "XP_027281159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281159" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281159" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Aspscr1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92", "locus": {} } ], "crossref": [ { "id": "A0A9J7GA92", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GA92", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16105", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16105", "database": "CDD", "categories": [ "Protein Classification" ] 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"PF11470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281159", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GA92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GA92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDA8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5D9-1", "url": 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"MAAPAAAGAPRCRAGPKRAAHTVKVTPSTVLLQVLEDTCRRQDFNPSEYDLKFQRTVLDLSLQWRFANLPNNAKLEMVPVSRSREGPENMVRIALQLDDGSRLQDTFCSRQTLWELLSHFVQTRERLQHLGERTPVCVYMRDEVTGRTALQNTTLQSLGLTGGSATIRFVIKQCDTVGKQEPIAVRSKAPGSPISSMSADQASSSPLLPLNSGEFSRGDLNHQGDANTSEASLGSGPKPADAQTKQSTKESASAPFVPFSGGGQRLGGPSGSLRSLTSHSAKSLKSSSGSGGPSKPKKSKPGEEPQQEPEPPVDRDPVVCHPDLEDLLQPWPAEVPDEFFEVTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQMKEKLERYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTLTLFQANLFPAALVHFGAEEPAGLYLEPGLLEHTVSPSAADVLVARCMSRAAGSPPLLPAPDSVSLESEPITEEGALGPPEPIQGAAQPVRRSLGKVPKWLKLPAGKR", "length": 549, "header": "tr|A0A9J7GA92-1|A0A9J7GA92_CRIGR Isoform 1 of Tether containing UBX domain for GLUT4 OS=Cricetulus griseus OX=10029 GN=Aspscr1 PE=4 SV=1 CANONICAL=A0A9J7GA92-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GA92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92/entry#A0A9J7GA92-1", "sequence": { "sequence": "MAAPAAAGAPRCRAGPKRAAHTVKVTPSTVLLQVLEDTCRRQDFNPSEYDLKFQRTVLDLSLQWRFANLPNNAKLEMVPVSRSREGPENMVRIALQLDDGSRLQDTFCSRQTLWELLSHFVQTRERLQHLGERTPVCVYMRDEVTGRTALQNTTLQSLGLTGGSATIRFVIKQCDTVGKQEPIAVRSKAPGSPISSMSADQASSSPLLPLNSGEFSRGDLNHQGDANTSEASLGSGPKPADAQTKQSTKESASAPFVPFSGGGQRLGGPSGSLRSLTSHSAKSLKSSSGSGGPSKPKKSKPGEEPQQEPEPPVDRDPVVCHPDLEDLLQPWPAEVPDEFFEVTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQMKEKLERYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTLTLFQANLFPAALVHFGAEEPAGLYLEPGLLEHTVSPSAADVLVARCMSRAAGSPPLLPAPDSVSLESEPITEEGALGPPEPIQGAAQPVRRSLGKVPKWLKLPAGKR", "length": 549, "header": "tr|A0A9J7GA92-1|A0A9J7GA92_CRIGR Isoform 1 of Tether containing UBX domain for GLUT4 OS=Cricetulus griseus OX=10029 GN=Aspscr1 PE=4 SV=1 CANONICAL=A0A9J7GA92-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92/entry#A0A9J7GDA8-1", "sequence": { "sequence": "MAAPAAAGAPRCRAGPKRAAHTVKVTPSTVLLQVLEDTCRRQDFNPSEYDLKFQRTVLDLSLQWRFANLPNNAKLEMVPVSRSREGPENMVRIALQLDDGSRLQDTFCSRQTLWELLSHFVQTRERLQHLGERTPVCVYMRDEVTGRTALQNTTLQSLGLTGGSATIRFVIKQCDTVGKQEPIAVRSKAPGSPISSMSADQASSSPLLPLNSGEFSRGDLNHQGDANTSEASLGSGPKPADAQTKQSTKESASAPFVPFSGGGQRLGGPSGSLRSLTSHSAKSLKSSSGSGGPSKPKKSKPGEEPQQEPEPPVDRDPVVCHPDLEDLLQPWPAEVPDEFFEVTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQMKEKLERYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTLTLFQANLFPAALVHFGAEEPAVCG", "length": 466, "header": "tr|A0A9J7GDA8-1|A0A9J7GDA8_CRIGR Computationally mapped isoform of Tether containing UBX domain for GLUT4 OS=Cricetulus griseus OX=10029 GN=Aspscr1 PE=4 SV=1 CANONICAL=A0A9J7GA92-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92/entry#A0A9J7H5D9-1", "sequence": { "sequence": "MAAPAAAGAPRCRAGPKRAAHTVKVTPSTVLLQVLEDTCRRQDFNPSEYDLKFQRTVLDLSLQWRFANLPNNAKLEMVPVSRSREGPENMVRIALQLDDGSRLQDTFCSRQTLWELLSHFVQTRERLQHLGERTPVCVYMRDEVTGRTALQNTTLQSLGLTGGSATIRFVIKQCDTVGKQEPIAVRSKAPGSPISSMSADQASSSPLLPLNSGEFSRGDLNHQGDANTSEASLGSGPKPADAQTKQSTKESASAPFVPFSGGGQRLGGPSGSLRSLTSHSAKSLKSSSGSGGPSKPKKSKPGEEPQQEPEPPVDRDPVVCHPDLEDLLQPWPAEVPDEFFEVTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQMKEKLERYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTLTLFQANLFPAALVHFGAEEPAESNHSEVLVGLGDLQPRTHLPGAPA", "length": 488, "header": "tr|A0A9J7H5D9-1|A0A9J7H5D9_CRIGR Computationally mapped isoform of Tether containing UBX domain for GLUT4 OS=Cricetulus griseus OX=10029 GN=Aspscr1 PE=4 SV=1 CANONICAL=A0A9J7GA92-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92/entry#A0A9J7KAG9-1", "sequence": { "sequence": "MDLTPVFLWRTADLSLFSLRERLQHLGERTPVCVYMRDEVTGRTALQNTTLQSLGLTGGSATIRFVIKQCDTVGKQEPIAVRSKAPGSPISSMSADQASSSPLLPLNSGEFSRGDLNHQGDANTSEASLGSGPKPADAQTKQSTKESASAPFVPFSGGGQRLGGPSGSLRSLTSHSAKSLKSSSGSGGPSKPKKSKPGEEPQQEPEPPVDRDPVVCHPDLEDLLQPWPAEVPDEFFEVTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQMKEKLERYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTLTLFQANLFPAALVHFGAEEPAGLYLEPGLLEHTVSPSAADVLVARCMSRAAGSPPLLPAPDSVSLESEPITEEGALGPPEPIQGAAQPVRRSLGKVPKWLKLPAGKR", "length": 445, "header": "tr|A0A9J7KAG9-1|A0A9J7KAG9_CRIGR Computationally mapped isoform of Tether containing UBX domain for GLUT4 isoform X8 OS=Cricetulus griseus OX=10029 GN=Aspscr1 PE=4 SV=1 CANONICAL=A0A9J7GA92-1" }, "locus": {} }, { "isoform_ac": "G3GXC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92/entry#G3GXC5-1", "sequence": { "sequence": "MVPVSRSREGPENMVRIALQLDDGSRLQDTFCSRQTLWELLSHFVQTRERLQHLGERTPVCVYMRDEVTGRTALQNTTLQSLGLTGGSATIRFVIKQCDTVGKQEPIAVRSKAPGSPISSMSADQASSSPLLPLNSGEFSRGDLNHQGDANTSEASLGSGPKPADAQTKQSTKESASAPFVPFSGGGQRLGGPSGSLRSLTSHSAKSLKSSSGSGGPSKPKKSKPGEEPQQEPEPPVDRDPVVCHPDLEDLLQPWPAEVPDEFFEVTVDDVRRRLAQLKSERKRLEEAPLVTKAFREAQMKEKLERYPKVALRVLFPDRYILQGFFRPSETVGDLRDFVRSHLGNPELSFYLFIAPPKMVLDDHTLTLFQANLFPAALVHFGAEEPAGLYLEPGLLEHTVSPSAADVLVARCMSRAAGSPPLLPAPDSVSLESEPITEEGALGPPEPIQGAAQPVRRSLGKVPKWLKLPAGKR", "length": 473, "header": "tr|G3GXC5-1|A0A9J7GA92_CRIGR Computationally mapped isoform of Tether containing UBX domain for GLUT4 OS=Cricetulus griseus OX=10029 GN=Aspscr1 PE=4 SV=1 CANONICAL=A0A9J7GA92-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GXC5", "url": "https://www.uniprot.org/uniprotkb/G3GXC5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GXC5", "url": "https://www.uniprot.org/uniprotkb/G3GXC5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768779", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768779", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92" } ], "pmid": "" }, { "name": "endoplasmic reticulum-Golgi intermediate compartment membrane", "id": "GO:0033116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033116", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92" } ], "pmid": "" }, { "name": "glucose homeostasis", "id": "GO:0042593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042593", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GA92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA92" }, { "id": "PS50033", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBX", "eco_id": "ECO_0000259", "start_pos": 381, "end_pos": 457, "start_aa": "Glu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 227, "end_pos": 229 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"XP_007606097", "name": "ral GTPase-activating protein subunit beta isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007606097" }, "gene_names": [ { "name": "Ralgapb", "type": "recommended", "evidence": [ { "id": "A0A9J7G5Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4" } ] }, { "name": "Ralgapb", "type": "synonym", "evidence": [ { "id": "XP_007606097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007606097" } ] } ], "protein_names": [ { "name": "Ral GTPase-activating protein subunit beta", "type": "recommended", "evidence": [ { "id": "A0A9J7G5Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4/entry#names_and_taxonomy" } ] }, { "name": "p170", "type": "synonym", "evidence": [ { "id": "A0A9J7G5Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4/entry#names_and_taxonomy" } ] }, { "name": "ral GTPase-activating protein subunit beta isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007606097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007606097" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613641.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007606097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007606097" } ] }, { "annotation": "Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALB.", "evidence": [ { "database": "UniProtKB", "id": "G3GXZ7", "url": "https://www.uniprot.org/uniprotkb/G3GXZ7#function" }, { "database": "UniProtKB", "id": "ARBA00053327", "url": "https://www.uniprot.org/uniprotkb/ARBA00053327#function" }, { "database": "UniProtKB", "id": "A0A9J7G5Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4#function" }, { "database": "UniProtKB", "id": "A0A9J7G9B4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9B4#function" }, { "database": "UniProtKB", "id": "A0A9J7JV25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV25#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ralgapb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4", "locus": {} } ], "crossref": [ { "id": "100760158", "url": "https://www.ncbi.nlm.nih.gov/gene/100760158", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760158", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760158", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G5Q4", "url": "https://www.orthodb.org/?gene=A0A9J7G5Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G9B4", "url": "https://www.orthodb.org/?gene=A0A9J7G9B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JV25", "url": "https://www.orthodb.org/?gene=A0A9J7JV25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3GXZ7", "url": "https://www.orthodb.org/?gene=G3GXZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21344:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21344:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007606097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007606097", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G5Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9B4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9B4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JV25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JV25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3GXZ7", "url": "https://www.uniprot.org/uniprotkb/G3GXZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3GXZ7-1", "url": "https://www.uniprot.org/uniprotkb/G3GXZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYSEWRSLHLVIQNDQGHTSVLHSYPESVGREVANAVVRPLGQALGTSSVAGSESLLKTDKEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPIIKEPNLYVQSILKHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLSEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSTAVNTTPPHNRRHRAVTVNKATMKTSAVTTVHTSKVQHQASSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAIATQASMEFRRKGSQMSTDTMVSNPVFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDYVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYDVALGYILALNTDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDLGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEDRHEKLRSGMAQQIAYEIHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRNVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINSCDDGEGSEQDEVNSSEDAGASIFNGQKKVLYYADALTEIAFVVPSPMESLTDSLESNISDQDSDSNMDLMPGILKQPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGRHVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "length": 1503, "header": "tr|A0A9J7G5Q4-1|A0A9J7G5Q4_CRIGR Isoform 1 of Ral GTPase-activating protein subunit beta OS=Cricetulus griseus OX=10029 GN=Ralgapb PE=4 SV=1 CANONICAL=A0A9J7G5Q4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G5Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4/entry#A0A9J7G5Q4-1", "sequence": { "sequence": "MYSEWRSLHLVIQNDQGHTSVLHSYPESVGREVANAVVRPLGQALGTSSVAGSESLLKTDKEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPIIKEPNLYVQSILKHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLSEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSTAVNTTPPHNRRHRAVTVNKATMKTSAVTTVHTSKVQHQASSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAIATQASMEFRRKGSQMSTDTMVSNPVFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDYVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYDVALGYILALNTDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDLGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEDRHEKLRSGMAQQIAYEIHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRNVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINSCDDGEGSEQDEVNSSEDAGASIFNGQKKVLYYADALTEIAFVVPSPMESLTDSLESNISDQDSDSNMDLMPGILKQPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGRHVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "length": 1503, "header": "tr|A0A9J7G5Q4-1|A0A9J7G5Q4_CRIGR Isoform 1 of Ral GTPase-activating protein subunit beta OS=Cricetulus griseus OX=10029 GN=Ralgapb PE=4 SV=1 CANONICAL=A0A9J7G5Q4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4/entry#A0A9J7G9B4-1", "sequence": { "sequence": "MYSEWRSLHLVIQNDQGHTSVLHSYPESVGREVANAVVRPLGQALGTSSVAGSESLLKTDKEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPIIKEPNLYVQSILKHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLSEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSTAVNTTPPHNRRHRAVTVNKATMKTSAVTTVHTSKVQHQASSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAIATQASMEFRRKGSQMSTDTMVSNPVFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDYVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDLGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEDRHEKLRSGMAQQIAYEIHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRNVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINSCDDGEGSEQDEVNSSEDAGASIFNGQKKVLYYADALTEIAFVVPSPMESLTDSLESNISDQDSDSNMDLMPGILKQPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGRHVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "length": 1491, "header": "tr|A0A9J7G9B4-1|A0A9J7G9B4_CRIGR Computationally mapped isoform of Ral GTPase-activating protein subunit beta OS=Cricetulus griseus OX=10029 GN=Ralgapb PE=4 SV=1 CANONICAL=A0A9J7G5Q4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JV25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4/entry#A0A9J7JV25-1", "sequence": { "sequence": "MARETWEVLLLFLLQINDILLAPPTVQGGIAENLSEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSTAVNTTPPHNRRHRAVTVNKATMKTSAVTTVHTSKVQHQASSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAIATQASMEFRRKGSQMSTDTMVSNPVFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDYVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYDVALGYILALNTDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDLGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEDRHEKLRSGMAQQIAYEIHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRNVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINSCDDGEGSEQDEVNSSEDAGASIFNGQKKVLYYADALTEIAFVVPSPMESLTDSLESNISDQDSDSNMDLMPGILKQPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGRHVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "length": 1346, "header": "tr|A0A9J7JV25-1|A0A9J7JV25_CRIGR Computationally mapped isoform of Ral GTPase-activating protein subunit beta OS=Cricetulus griseus OX=10029 GN=Ralgapb PE=4 SV=1 CANONICAL=A0A9J7G5Q4-1" }, "locus": {} }, { "isoform_ac": "G3GXZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4/entry#G3GXZ7-1", "sequence": { "sequence": "MYSEWRSLHLVIQNDQGHTSVLHSYPESVGREVANAVVRPLGQALGTSSVAGSESLLKTDKEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPIIKEPNLYVQSILKHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLSEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSTAVNTTPPHNRRHRAVTVNKATMKTSAVTTVHTSKVQHQASSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAIATQASMEFRRKGSQMSTDTMVSNPVFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDYVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYALNTDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDLGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNSEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEDRHEKLRSGMAQQIAYEIHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRNVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINSCDDGEGSEQDEVNSSEDAGASIFNGQKKVLYYADALTEIAFVVPSPMESLTDSLESNISDQDSDSNMDLMPGILKQPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGRHVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "length": 1495, "header": "tr|G3GXZ7-1|A0A9J7G5Q4_CRIGR Computationally mapped isoform of Ral GTPase-activating protein subunit beta OS=Cricetulus griseus OX=10029 GN=Ralgapb PE=4 SV=1 CANONICAL=A0A9J7G5Q4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 213, "start_aa": "Thr", "end_pos": 213, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr213", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 363, "start_aa": "Thr", "end_pos": 363, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr363", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GXZ7", "url": "https://www.uniprot.org/uniprotkb/G3GXZ7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GXZ7", "url": "https://www.uniprot.org/uniprotkb/G3GXZ7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760158", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760158", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1244, "end_pos": 1246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1288, "end_pos": 1290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1317, "end_pos": 1319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1323, "end_pos": 1325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1384, "end_pos": 1386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1500, "end_pos": 1502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" }, { "start_pos": 935, "end_pos": 937, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G5Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Q4" }, { "id": "PS50085", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50085" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rap-GAP", "eco_id": "ECO_0000259", "start_pos": 1157, "end_pos": 1401, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 213, 363 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1244, "end_pos": 1246 }, { "start_pos": 1288, "end_pos": 1290 }, { "start_pos": 1317, "end_pos": 1319 }, { "start_pos": 1323, "end_pos": 1325 }, { "start_pos": 1384, "end_pos": 1386 }, { "start_pos": 1500, "end_pos": 1502 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 314, "end_pos": 316 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 677, "end_pos": 679 }, { "start_pos": 935, "end_pos": 937 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G9W2-1", "uniprot_ac": "A0A9J7G9W2", "uniprot_id": "A0A9J7G9W2_CRIGR", "mass": { "chemical_mass": 56195.0, "monoisotopic_mass": 56195.0 }, "refseq": { "ac": "XP_027278606", "name": "diphthine methyltransferase isoform X9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278606" }, "gene_names": [ { "name": "Dph7", "type": "recommended", "evidence": [ { "id": "A0A9J7G9W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2" } ] }, { "name": "Dph7", "type": "synonym", "evidence": [ { "id": "XP_027278606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278606" } ] } ], "protein_names": [ { "name": "methylated diphthine methylhydrolase", "type": "recommended", "evidence": [ { "id": "A0A9J7G9W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.97", "type": "synonym", "evidence": [ { "id": "A0A9J7G9W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2/entry#names_and_taxonomy" } ] }, { "name": "diphthine methyltransferase isoform X9", "type": "synonym", "evidence": [ { "id": "XP_027278606", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278606" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278606" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9W2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dph7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2", "locus": {} } ], "crossref": [ { "id": "A0A9J7G9W2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G9W2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100753959", "url": "https://www.ncbi.nlm.nih.gov/gene/100753959", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753959", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753959", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9W2", "url": "https://www.orthodb.org/?gene=A0A9J7G9W2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46042", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46042", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46042:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46042:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278606", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278606", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "42656", "url": "https://www.rhea-db.org/rhea/42656", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G7U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7U1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7U1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G839", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G839", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G839-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G839-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9W2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9W7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCI3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVY5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGSWSGTMQALQAVDTEYTADSVEWCPVEGCQHLLVCGTYQLRTPEDQPALDVSEPQVRLGRLYLYSFNEDNTAKPLVEVQRRDSSAILDMKWCHIPVSGHILLGLANANGSVELLRLMEYEKNSYTLQPISSLILEERCLSLSLDWSTGKPGRYPRGRLGGMVVCYLRKIWGLEEDGCDGSFCNASIQEAEAGGFQVVGDQPLKMISSDSKGQLHLLMLSEGAAELQRVASWPAHHFEAWIAAFNYWQTELVYSGGDDGLLRGWDTRMLGTPVFTSKRHSMGVCSIQSNPHQEHILATGSYDEHVLLWDTRNIKQPLADVPVKGGVWRLKWHPVHPHLLLAVCMHNGFKILNCQKAIEEKQDVTVLISQEMPNSLVYGADWSWLLFRSKKPTLTWSFDQNGMGAQAADHCSLKVAEGPPAPFQEQIVDHHVEGPTKAHRRAELNTSLLPLTEDMKSFSQLHCSSKICDLSPFSGGNFDSSLLSTCSFYDHVLHLWKWETK", "length": 502, "header": "tr|A0A9J7G9W2-1|A0A9J7G9W2_CRIGR Isoform 1 of methylated diphthine methylhydrolase OS=Cricetulus griseus OX=10029 GN=Dph7 PE=3 SV=1 CANONICAL=A0A9J7G9W2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G7U1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2/entry#A0A9J7G7U1-1", "sequence": { "sequence": "MAGSWSGTMQALQAVDTEYTADSVEWCPVEGCQHLLVCGTYQLRTPEDQPALDVSEPQVRLGRLYLYSFNEDNTAKPLVEVQRRDSSAILDMKWCHIPVSGHILLGLANANGSVELLRLMEYEKNSYTLQPISSLILEERCLSLSLDWSTGKPGRYPRGRLGGMVVCYLRKIWGLEEDGCDGSFCNASIQEAEAGGFQVVGDQPLKMISSDSKGQLHLLMLSEGAAELQRVASWPAHHFEAWIAAFNYWQTELVYSGGDDGLLRGWDTRMLGTPVFTSKRHSMGVCSIQSNPHQEHILATGSYDEHVLLWDTRNIKQPLADVPVKGGVWRLKWHPVHPHLLLAVCMHNGFKILNCQKAIASPGSHVTQTGFNCLCLPSSGIKGIRHHRPPFFILLMQTCQLLSECVLTEWLPLVEVEGRHKWRLISFA", "length": 428, "header": "tr|A0A9J7G7U1-1|A0A9J7G7U1_CRIGR Computationally mapped isoform of methylated diphthine methylhydrolase OS=Cricetulus griseus OX=10029 GN=Dph7 PE=3 SV=1 CANONICAL=A0A9J7G9W2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G839-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2/entry#A0A9J7G839-1", "sequence": { "sequence": "MVVCYLRKIWGLEEDGCDGSFCNASIQEAEAGGFQVVGDQPLKMISSDSKGQLHLLMLSEGAAELQRVASWPAHHFEAWIAAFNYWQTELVYSGGDDGLLRGWDTRMLGTPVFTSKRHSMGVCSIQSNPHQEHILATGSYDEHVLLWDTRNIKQPLADVPVKGGVWRLKWHPVHPHLLLAVCMHNGFKILNCQKAIEEKQDVTVLISQEMPNSLVYGADWSWLLFRSKKPTLTWSFDQNGMGAQAADHCSLKVAEGPPAPFQEQIVDHHVEGPTKAHRRAELNTSLLPLTEDMKSFSQLHCSSKICDLSPFSGGNFDSSLLSTCSFYDHVLHLWKWETK", "length": 339, "header": "tr|A0A9J7G839-1|A0A9J7G839_CRIGR Computationally mapped isoform of methylated diphthine methylhydrolase OS=Cricetulus griseus OX=10029 GN=Dph7 PE=3 SV=1 CANONICAL=A0A9J7G9W2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9W2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2/entry#A0A9J7G9W2-1", "sequence": { "sequence": "MAGSWSGTMQALQAVDTEYTADSVEWCPVEGCQHLLVCGTYQLRTPEDQPALDVSEPQVRLGRLYLYSFNEDNTAKPLVEVQRRDSSAILDMKWCHIPVSGHILLGLANANGSVELLRLMEYEKNSYTLQPISSLILEERCLSLSLDWSTGKPGRYPRGRLGGMVVCYLRKIWGLEEDGCDGSFCNASIQEAEAGGFQVVGDQPLKMISSDSKGQLHLLMLSEGAAELQRVASWPAHHFEAWIAAFNYWQTELVYSGGDDGLLRGWDTRMLGTPVFTSKRHSMGVCSIQSNPHQEHILATGSYDEHVLLWDTRNIKQPLADVPVKGGVWRLKWHPVHPHLLLAVCMHNGFKILNCQKAIEEKQDVTVLISQEMPNSLVYGADWSWLLFRSKKPTLTWSFDQNGMGAQAADHCSLKVAEGPPAPFQEQIVDHHVEGPTKAHRRAELNTSLLPLTEDMKSFSQLHCSSKICDLSPFSGGNFDSSLLSTCSFYDHVLHLWKWETK", "length": 502, "header": "tr|A0A9J7G9W2-1|A0A9J7G9W2_CRIGR Isoform 1 of methylated diphthine methylhydrolase OS=Cricetulus griseus OX=10029 GN=Dph7 PE=3 SV=1 CANONICAL=A0A9J7G9W2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2/entry#A0A9J7G9W7-1", "sequence": { "sequence": "MAGSWSGTMQALQAVDTEYTADSVEWCPVEGCQHLLVCGTYQLRTPEDQPALDVSEPQVRLGRLYLYSFNEDNTAKPLVEVQRRDSSAILDMKWCHIPVSGHILLGLANANGSVELLRLMEYEKNSYTLQPISSLILEERCLSLSLDWSTGKPGRVGDQPLKMISSDSKGQLHLLMLSEGAAELQRVASWPAHHFEAWIAAFNYWQTELVYSGGDDGLLRGWDTRMLGTPVFTSKRHSMGVCSIQSNPHQEHILATGSYDEHVLLWDTRNIKQPLADVPVKGGVWRLKWHPVHPHLLLAVCMHNGFKILNCQKAIEEKQDVTVLISQEMPNSLVYGADWSWLLFRSKKPTLTWSFDQNGMGAQAADHCSLKVAEGPPAPFQEQIVDHHVEGPTKAHRRAELNTSLLPLTEDMKSFSQLHCSSKICDLSPFSGGNFDSSLLSTCSFYDHVLHLWKWETK", "length": 458, "header": "tr|A0A9J7G9W7-1|A0A9J7G9W2_CRIGR Computationally mapped isoform of methylated diphthine methylhydrolase OS=Cricetulus griseus OX=10029 GN=Dph7 PE=3 SV=1 CANONICAL=A0A9J7G9W2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2/entry#A0A9J7GCI3-1", "sequence": { "sequence": "MKWCHIPVSGHILLGLANANGSVELLRLMEYEKNSYTLQPISSLILEERCLSLSLDWSTGKPGRYPRGRLGGMVVCYLRKIWGLEEDGCDGSFCNASIQEAEAGGFQVVGDQPLKMISSDSKGQLHLLMLSEGAAELQRVASWPAHHFEAWIAAFNYWQTELVYSGGDDGLLRGWDTRMLGTPVFTSKRHSMGVCSIQSNPHQEHILATGSYDEHVLLWDTRNIKQPLADVPVKGGVWRLKWHPVHPHLLLAVCMHNGFKILNCQKAIEEKQDVTVLISQEMPNSLVYGADWSWLLFRSKKPTLTWSFDQNGMGAQAADHCSLKVAEGPPAPFQEQIVDHHVEGPTKAHRRAELNTSLLPLTEDMKSFSQLHCSSKICDLSPFSGGNFDSSLLSTCSFYDHVLHLWKWETK", "length": 411, "header": "tr|A0A9J7GCI3-1|A0A9J7GCI3_CRIGR Computationally mapped isoform of methylated diphthine methylhydrolase OS=Cricetulus griseus OX=10029 GN=Dph7 PE=3 SV=1 CANONICAL=A0A9J7G9W2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JMB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2/entry#A0A9J7JMB1-1", "sequence": { "sequence": "MVVMVLFVMPAFRRLRVGDQPLKMISSDSKGQLHLLMLSEGAAELQRVASWPAHHFEAWIAAFNYWQTELVYSGGDDGLLRGWDTRMLGTPVFTSKRHSMGVCSIQSNPHQEHILATGSYDEHVLLWDTRNIKQPLADVPVKGGVWRLKWHPVHPHLLLAVCMHNGFKILNCQKAIEEKQDVTVLISQEMPNSLVYGADWSWLLFRSKKPTLTWSFDQNGMGAQAADHCSLKVAEGPPAPFQEQIVDHHVEGPTKAHRRAELNTSLLPLTEDMKSFSQLHCSSKICDLSPFSGGNFDSSLLSTCSFYDHVLHLWKWETK", "length": 319, "header": "tr|A0A9J7JMB1-1|A0A9J7JMB1_CRIGR Computationally mapped isoform of methylated diphthine methylhydrolase OS=Cricetulus griseus OX=10029 GN=Dph7 PE=3 SV=1 CANONICAL=A0A9J7G9W2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2/entry#A0A9J7JSR2-1", "sequence": { "sequence": "MAGSWSGTMQALQAVDTEYTADSVEWCPVEGCQHLLVCGTYQLRTPEDQPALDVSEPQVRLGRLYLYSFNEDNTAKPLVEVQRRDSSAILDMKWCHIPVSGHILLGLANANGSVELLRLMEYEKNSYTLQPISSLILEERCLSLSLDWSTGKPGRYPRGRLGGMVVCYLRKIWGLEEDGCDGSFCNASIQEAEAGGFQVVGDQPLKMISSDSKGQLHLLMLSEGAAELQRVASWPAHHFEAWIAAFNYWQTELVYSGGDDGLLRGWDTRMLGTPVFTSKRHSMGVCSIQSNPHQEHILATGSYDEHVLLWDTRNIKQPLADVPVKGGVWRLKWHPVHPHLLLAVCMHNGFKILNCQKAIDPGIS", "length": 364, "header": "tr|A0A9J7JSR2-1|A0A9J7JSR2_CRIGR Computationally mapped isoform of methylated diphthine methylhydrolase OS=Cricetulus griseus OX=10029 GN=Dph7 PE=3 SV=1 CANONICAL=A0A9J7G9W2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2/entry#A0A9J7JVY5-1", "sequence": { "sequence": "MISSDSKGQLHLLMLSEGAAELQRVASWPAHHFEAWIAAFNYWQTELVYSGGDDGLLRGWDTRMLGTPVFTSKRHSMGVCSIQSNPHQEHILATGSYDEHVLLWDTRNIKQPLADVPVKGGVWRLKWHPVHPHLLLAVCMHNGFKILNCQKAIEEKQDVTVLISQEMPNSLVYGADWSWLLFRSKKPTLTWSFDQNGMGAQAADHCSLKVAEGPPAPFQEQIVDHHVEGPTKAHRRAELNTSLLPLTEDMKSFSQLHCSSKICDLSPFSGGNFDSSLLSTCSFYDHVLHLWKWETK", "length": 296, "header": "tr|A0A9J7JVY5-1|A0A9J7JVY5_CRIGR Computationally mapped isoform of methylated diphthine methylhydrolase OS=Cricetulus griseus OX=10029 GN=Dph7 PE=3 SV=1 CANONICAL=A0A9J7G9W2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 437, "start_aa": "Thr", "end_pos": 437, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr437", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9W7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9W7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753959", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753959", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "diphthine methylesterase activity", "id": "GO:0061685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061685", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9W2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2" } ], "pmid": "" }, { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9W2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9W2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9W2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2" } ], "pmid": "" }, { "name": "protein histidyl modification to diphthamide", "id": "GO:0017183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017183", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9W2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280133", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280133" } ] }, { "annotation": "Binds cAMP regulatory element DNA sequence. 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Pathway" ] }, { "id": "A0A3L7HDV0", "url": "https://www.orthodb.org/?gene=A0A3L7HDV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G9N8", "url": "https://www.orthodb.org/?gene=A0A9J7G9N8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GA54", "url": "https://www.orthodb.org/?gene=A0A9J7GA54", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12375", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12375", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03194", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03194", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280133", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280133", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HDV0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDV0", "database": "UniProtKB", 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRSRDHKRSRSRDRRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSSSREKQSEDTNPESKESDTKNEVNGTSEDIKSEVQRKYAQMKTDLSRVRRHTKASSEGKDSVVLQNILRYIVLSQLFCSRLVPPLVCLFGNYCPRM", "length": 486, "header": "tr|A0A9J7G9N8-1|A0A9J7G9N8_CRIGR Isoform 1 of Luc7-like protein OS=Cricetulus griseus OX=10029 GN=Luc7l3 PE=3 SV=1 CANONICAL=A0A9J7G9N8-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HDV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N8/entry#A0A3L7HDV0-1", "sequence": { "sequence": "MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRSRDHKRSRSRDRRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSSSREKQSEDTNPESKESDTKNEVNGTSEDIKSEVQRKYAQMKTDLSRVRRHTKASSEGKDSVVLQNILRTTVEDFLKNTENGIQ", "length": 474, "header": "tr|A0A3L7HDV0-1|A0A3L7HDV0_CRIGR Computationally mapped isoform of Luc7-like protein OS=Cricetulus griseus OX=10029 GN=Luc7l3 PE=3 SV=1 CANONICAL=A0A9J7G9N8-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QF06-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N8/entry#A0A8C2QF06-1", "sequence": { "sequence": "MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRSRDHKRSRSRDRRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSSSREKQSEDTNPESKESDTKNEVNGTSEDIKSEVQRKYAQMKTDLSRVRRHTKASSEGKDSVVLQNILSVGVVSGP", "length": 466, "header": "tr|A0A8C2QF06-1|A0A9J7G9N8_CRIGR Computationally mapped isoform of Luc7-like protein OS=Cricetulus griseus OX=10029 GN=Luc7l3 PE=3 SV=1 CANONICAL=A0A9J7G9N8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N8/entry#A0A9J7G9N8-1", "sequence": { "sequence": "MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRSRDHKRSRSRDRRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSSSREKQSEDTNPESKESDTKNEVNGTSEDIKSEVQRKYAQMKTDLSRVRRHTKASSEGKDSVVLQNILRYIVLSQLFCSRLVPPLVCLFGNYCPRM", "length": 486, "header": "tr|A0A9J7G9N8-1|A0A9J7G9N8_CRIGR Isoform 1 of Luc7-like protein OS=Cricetulus griseus OX=10029 GN=Luc7l3 PE=3 SV=1 CANONICAL=A0A9J7G9N8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GA54-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N8/entry#A0A9J7GA54-1", "sequence": { "sequence": "MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRSRDHKRSRSRDRRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSSSREKQSEDTNPESKESDTKNEVNGTSEDIKSEGDTQSN", "length": 429, "header": "tr|A0A9J7GA54-1|A0A9J7GA54_CRIGR Computationally mapped isoform of Luc7-like protein OS=Cricetulus griseus OX=10029 GN=Luc7l3 PE=3 SV=1 CANONICAL=A0A9J7G9N8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N8/entry#A0A9J7JTT0-1", "sequence": { "sequence": "MISAAQLLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENLRKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRSRDHKRSRSRDRRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKGQKIRFLDY", "length": 385, "header": "tr|A0A9J7JTT0-1|A0A9J7JTT0_CRIGR Computationally mapped isoform of RNA-binding protein Luc7-like OS=Cricetulus griseus OX=10029 GN=Luc7l3 PE=3 SV=1 CANONICAL=A0A9J7G9N8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QF06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QF06" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QF06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QF06" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767266", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767266", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "U1 snRNP", "id": "GO:0005685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005685", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N8" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splice site recognition", "id": "GO:0006376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006376", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9N8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 414, "end_pos": 416 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G514-1", "uniprot_ac": "A0A9J7G514", "uniprot_id": "A0A9J7G514_CRIGR", "mass": { "chemical_mass": 133659.0, "monoisotopic_mass": 133659.0 }, "refseq": { "ac": "XP_027276440", "name": "liprin-alpha-3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276440" }, "gene_names": [ { "name": "Ppfia3", "type": "recommended", "evidence": [ { "id": "A0A9J7G514", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514" } ] }, { "name": "Ppfia3", "type": "synonym", "evidence": [ { "id": "XP_027276440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276440" } ] } ], "protein_names": [ { "name": "Liprin-alpha-3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7G514", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514/entry#names_and_taxonomy" } ] }, { "name": "liprin-alpha-3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027276440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276440" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276440" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G514", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppfia3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514", "locus": {} } ], "crossref": [ { "id": "cd09562", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09562", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09565", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09565", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09568", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09568", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770934", "url": "https://www.ncbi.nlm.nih.gov/gene/100770934", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770934", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770934", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LMMMCEV", "url": "https://omabrowser.org/oma/group/LMMMCEV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G514", "url": "https://www.orthodb.org/?gene=A0A9J7G514", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25526", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25526", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276440", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QHN4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QHN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G514", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G514-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G540", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G540", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G540-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G540-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMCEVMPTISEDGRRGSALGPDEAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQETLNLRDQLSRRRSGLEEPGKDGDGQTLANGLGPIGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLSKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAPLDPYGAGSGRAGKRGRWSGAKDESSKGQDWDRSTPAGSIPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTEKTNHVPKEEAGVPRGEGPAIPGDTPPPTPRSARLERMTQALALQAGSLEDGAPPRGSEGTPDSLHKAPKKKSIKSSIGRLFGKKEKGRMGPPGRESASLAGTPSDETLATDPLGLSKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTPTGNVWMTHEEMESLTAATKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC", "length": 1196, "header": "tr|A0A9J7G514-1|A0A9J7G514_CRIGR Isoform 1 of Liprin-alpha-3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfia3 PE=3 SV=1 CANONICAL=A0A9J7G514-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QHN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514/entry#A0A8C2QHN4-1", "sequence": { "sequence": "MMCEVMPTISEDGRRGSALGPDEAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQETLNLRDQLSRRRSGLEEPGKDGDGQTLANGLGPIGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLSKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAPLDPYGAGSGRAGKRGRWSGAKDESSKDWDRSTPAGSIPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTEKTNHVPKEEAGVPRGEGPAIPGDTPPPTPRSARLERMTQALALQAGSLEDGAPPRGSEGTPDSLHKAPKKKSIKSSIGRLFGKKEKGRMGPPGRESASLAGTPSDETLATDPLGLSKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTPTGNVWMTHEEMESLTAATKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC", "length": 1194, "header": "tr|A0A8C2QHN4-1|A0A9J7G514_CRIGR Computationally mapped isoform of Liprin-alpha-3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfia3 PE=3 SV=1 CANONICAL=A0A9J7G514-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G514-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514/entry#A0A9J7G514-1", "sequence": { "sequence": "MMCEVMPTISEDGRRGSALGPDEAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQETLNLRDQLSRRRSGLEEPGKDGDGQTLANGLGPIGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLSKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAPLDPYGAGSGRAGKRGRWSGAKDESSKGQDWDRSTPAGSIPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTEKTNHVPKEEAGVPRGEGPAIPGDTPPPTPRSARLERMTQALALQAGSLEDGAPPRGSEGTPDSLHKAPKKKSIKSSIGRLFGKKEKGRMGPPGRESASLAGTPSDETLATDPLGLSKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTPTGNVWMTHEEMESLTAATKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC", "length": 1196, "header": "tr|A0A9J7G514-1|A0A9J7G514_CRIGR Isoform 1 of Liprin-alpha-3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfia3 PE=3 SV=1 CANONICAL=A0A9J7G514-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G540-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514/entry#A0A9J7G540-1", "sequence": { "sequence": "MMCEVMPTISEDGRRGSALGPDEAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQETLNLRDQLSRRRSGLEEPGKDGDGQTLANGLGPIGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLSKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAPLDPYGAGSGRAGKRGRWSGAKDESSKGQDWDRSTPAGSIPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTEKTNHVPKEEAGVPRGEGPAIPGDTPPPTPRSARLERMTQALALQAGSLEDGAPPRGSEGTPDSLHKAPKKKSIKSSIGRLFGKKEKGRMGPPGRESASLAGTPSDETLATDPLGLSKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTPTGNVWMTHEEMESLTAATKPILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC", "length": 1187, "header": "tr|A0A9J7G540-1|A0A9J7G540_CRIGR Computationally mapped isoform of Liprin-alpha-3 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ppfia3 PE=3 SV=1 CANONICAL=A0A9J7G514-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 720, "start_aa": "Thr", "end_pos": 720, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr720", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QHN4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHN4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QHN4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHN4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770934", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770934", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MF33-1", "protein_name": "PTPRF interacting protein alpha 3", "gene_name": "PPFIA3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMCEVMPTISEDGRRGSALGPDEAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQETLSLREQLSRRRSGLEEPGKDGDGQTLANGLGPGGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANAKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAHLDPYGAGSGRASKRGRWSGVKDEPSKEWERSAPAGSMPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSGSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTDKANHVPKEEAVAPRGEGPAIPGDTPPPTPRSARLERMTQALALQAGSLEDGGPSRGSEGTPDSLHKAPKKKSIKSSIGRLFGKKEKGRMGPPGRDSSSLAGTPSDETLATDPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTSTGNVWMTHEEMESLTATTKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC", "length": 1194 }, "evidence": [ { "id": "A0A9J7G514", "url": "https://omabrowser.org/oma/group/A0A9J7G514/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LBV8-1", "protein_name": "PTPRF interacting protein alpha 3", "gene_name": "PPFIA3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMCEVMPTISEDGRRGSALGPDEAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQETLSLREQLSRRRSGLEEPGKDGDGQTLANGLGPGGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANAKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAHLDPYGAGSGRATKRGRWSGVKDEPSKEWERSAPAGPMPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSGSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGADKANHVPKEDAGAPRGEGPAIPGDTPPPTPRSARLERMTQALALQAGSLEDGGPSRGEGTPDSLHKAPKKKSIKSSIGRLFGKKEKGRMGPPGRDSSSLAGTPSDETLAADPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTSTGNVWMTHEEMESLTATTKPILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYTDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRAEGVSVRTYSC", "length": 1184 }, "evidence": [ { "id": "A0A9J7G514", "url": "https://omabrowser.org/oma/group/A0A9J7G514/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75145-1", "protein_name": "Liprin-alpha-3", "gene_name": "PPFIA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMCEVMPTISEDGRRGSALGPDEAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQETLNLREQLSRRRSGLEEPGKDGDGQTLANGLGPGGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAHLDPYVAGSGRAGKRGRWSGVKEEPSKDWERSAPAGSIPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTDKANHVPKEEAGAPRGEGPAIPGDTPPPTPRSARLERMTQALALQAGSLEDGGPPRGSEGTPDSLHKAPKKKSIKSSIGRLFGKKEKGRMGPPGRDSSSLAGTPSDETLATDPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTSTGNVWMTHEEMESLTATTKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC", "length": 1194 }, "evidence": [ { "id": "A0A9J7G514", "url": "https://omabrowser.org/oma/group/A0A9J7G514/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P60469-1", "protein_name": "Liprin-alpha-3", "gene_name": "Ppfia3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMCEVMPTISEDGRRGSALGPDEAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQEALNLRDQLSRRRSGLEEPGKDGDGQTLANGLGPVGESNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAPTLPSGAPLDPYGAGSGRAGKRGRWSGAKDESSKDWDRSAPAGSIPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTDKTNHVSKEEAGVPRGEGPAVPGDTPPPTPRSARLERMAQALALQAGSPEDGAPPRGSESTPDSLHKAPKRKSIKSSIGRLFGKKEKGRMGPPGRESVSLAGTPSDETLATDPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTPTGNVWMTHEEMESLTAATKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC", "length": 1194 }, "evidence": [ { "id": "A0A9J7G514", "url": "https://omabrowser.org/oma/group/A0A9J7G514/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91Z79-1", "protein_name": "Liprin-alpha-3", "gene_name": "Ppfia3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMCEVMPTISEDGRRGSALGPDDAGGELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQEALNLRDQLSRRRSGLEEPGKDGDGQTLANGLGPVGESSRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGRPPSYSRSLPGSALELRYSQAPTLPSGAPLDPYGAGSGRAGKRGRWSGAKDESSKDWDRSTPAGSIPPPFPGELDGSDEEETEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLDSLGRYRSSCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPARETDKTNHVPKDEAGVPRGEGPAIPGDTPPPTPRSARLERMTQALALQAGSLEDGAPPRGSESTPDSLHKAPKRKSIKSSIGRLFGKKEKGRMGPPGRESVSLAGTPSDETLATDPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTPTGNVWMTHEEMESLTAATKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELREQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC", "length": 1192 }, "evidence": [ { "id": "A0A9J7G514", "url": "https://omabrowser.org/oma/group/A0A9J7G514/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G514", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514" } ], "pmid": "" }, { "name": "presynaptic active zone cytoplasmic component", "id": "GO:0098831", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098831", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G514", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514" } ], "pmid": "" }, { "name": "acrosomal vesicle", "id": "GO:0001669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001669", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G514", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G514", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G514", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G514", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514" } ], "pmid": "" }, { "name": "synaptic vesicle docking", "id": "GO:0016081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016081", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G514", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1063, "end_pos": 1065, "annotation": "n_glycosylation_sequon" }, { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 875, "end_pos": 877, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G514", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G514" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 840, "end_pos": 906, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 720 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1063, "end_pos": 1065 }, { "start_pos": 111, "end_pos": 113 }, { "start_pos": 875, "end_pos": 877 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G3X6-1", "uniprot_ac": "A0A9J7G3X6", "uniprot_id": "A0A9J7G3X6_CRIGR", "mass": { "chemical_mass": 101778.0, "monoisotopic_mass": 101778.0 }, "refseq": { "ac": "XP_027272159", "name": "HHIP-like protein 1 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272159" }, "gene_names": [ { "name": "Hhipl1", "type": "recommended", "evidence": [ { "id": "A0A9J7G3X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6" } ] }, { "name": "Hhipl1", "type": "synonym", "evidence": [ { "id": "XP_027272159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272159" } ] } ], "protein_names": [ { "name": "HHIP-like protein 1 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_027272159", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272159" }, { "id": "A0A9J7G3X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272159" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hhipl1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6", "locus": {} } ], "crossref": [ { "id": "A0A9J7G3X6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G3X6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100769577", "url": "https://www.ncbi.nlm.nih.gov/gene/100769577", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769577", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769577", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G3X6", "url": "https://www.orthodb.org/?gene=A0A9J7G3X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19328:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19328:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272159", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272159", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FZF8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZM4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H022", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H022", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H022-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H022-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNE6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQ88", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQ88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQ88-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQ88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYCEVAASSLLPRAQTSLLVRSRATPPVSCTTPPFLNTLLRFLSGSEMGGTTNQESLLWALEFLLLGGQVGSVPRQEAETPRCNRATRLPRGQATALVGKARGQEEGAARRAGVRLCPASPVLQECSQAEIAWRMAGRRAVAGIGPGALLALRALLAAAHPQCLDFRPPFRPPQPLSFCVQYSSFGCCTAEQDAALARRFRALETRLDPGMWATCAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQICRGLFRHLSPDHELWALESNRAKLCRYLSLDDTDYCFPSLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHAGDGSHRFFVAEQVGLVWTYLPDLSRLEKPFLNVSQAVLTSPWEGDERGFLGLAFHPHFPHPSKLYVYYSVGVGYREWIRISEFRVSEDDENTVDHGSERIILEIEEPASNHNGGQLLFGYDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRNERGPPYRIPPDNPFVDDPGARPEVYALGVRNMWRCSFDRGDPMSGTGRGRLFCGDVGQNKYEEVDLVERGRNYGWRAREGFECYDRKLCANASLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENPETGQWKYSEVCMGRGQTCAFPGLINNYYPYIISFAEDEAGELYFMSTGVPSATAARGVIYKVIDPSRRAPPGKCKIHPAQVTVKSHLIPFVPKERFIRTPESTPRPTARAPTKAPRRRRPTAAPPAPTLRPTKPARPTRRPGARKGGGRRRGRPSTAVPAPQNGSVRLVRPAGLSPGRGRVEVFVGGHWGTVCDDAWDTKAAAVVCRQLGFAHAVRAAKRAEFGEGRALPILLDDVRCAGSERNLLECAHAGVGTHNCKHEEDAGVECSHQDPDL", "length": 925, "header": "tr|A0A9J7G3X6-1|A0A9J7G3X6_CRIGR Isoform 1 of HHIP-like protein 1 isoform X6 OS=Cricetulus griseus OX=10029 GN=Hhipl1 PE=3 SV=1 CANONICAL=A0A9J7G3X6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FZF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6/entry#A0A9J7FZF8-1", "sequence": { "sequence": "MYCEVAASSLLPRAQTSLLVRSRATPPVSCTTPPFLNTLLRFLSGSEMGGTTNQESLLWALEFLLLGGQVGSVPRQEAETPRCNRATRLPRGQATALVGKARGQEEGAARRAGVRLCPASPVLQECSQAEIAWRMAGRRAVAGIGPGALLALRALLAAAHPQCLDFRPPFRPPQPLSFCVQYSSFGCCTAEQDAALARRFRALETRLDPGMWATCAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQICRGLFRHLSPDHELWALESNRAKLCRYLSLDDTDYCFPSLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHAGDGSHRFFVAEQVGLVWTYLPDLSRLEKPFLNVSQAVLTSPWEGDERGFLGLAFHPHFPHPSKLYVYYSVGVGYREWIRISEFRVSEDDENTVDHGSERIILEIEEPASNHNGGQLLFGYDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRNERGPPYRIPPDNPFVDDPGARPEVYALGVRNMWRCSFDRGDPMSGTGRGRLFCGDVGQNKYEEVDLVERGRNYGWRAREGFECYDRKLCANASLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENPETGQWKYSEVCMGRGQTCAFPGLINNYYPYIISFAEDEAGELYFMSTGVPSATAARGVIYKVIDPSRVHPDTREHSSTHGPRPHQGASPQTPYGRSPGAHPTAHKARTAHPATRGQEGRRASAGTSEHRGPCAPERLGAPGTACGPESRPRARGSVCRRTLGHGVRRRLGHQGGRRGVSPAGLCARGASRQARGVRRGPRTTDPAGRRALRGQRAQPAGVRARWRGHA", "length": 878, "header": "tr|A0A9J7FZF8-1|A0A9J7FZF8_CRIGR Computationally mapped isoform of HHIP-like protein 1 isoform X7 OS=Cricetulus griseus OX=10029 GN=Hhipl1 PE=3 SV=1 CANONICAL=A0A9J7G3X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6/entry#A0A9J7FZM4-1", "sequence": { "sequence": "MYCEVAASSLLPRAQTSLLVRSRATPPVSCTTPPFLNTLLRFLSGSEMGGTTNQESLLWALEFLLLGGQVGSVPRQEAETPRCNRATRLPRGQATALVGKARGQEEGAARRAGVRLCPASPVLQECSQAEIAWRMAGRRAVAGIGPGALLALRALLAAAHPQCLDFRPPFRPPQPLSFCVQYSSFGCCTAEQDAALARRFRALETRLDPGMWATCAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQICRGLFRHLSPDHELWALESNRAKLCRYLSLDDTDYCFPSLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHAGDGSHRFFVAEQVGLVWTYLPDLSRLEKPFLNVSQAVLTSPWEGDERGFLGLAFHPHFPHPSKLYVYYSVGVGYREWIRISEFRVSEDDENTVDHGSERIILEIEEPASNHNGGQLLFGYDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRNERGPPYRIPPDNPFVDDPGARPEVYALGVRNMWRCSFDRGDPMSGTGRGRLFCGDVGQNKYEEVDLVERGRNYGWRAREGFECYDRKLCANASLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENPETGQWKYSEVCMGRGQTCAFPGLINNYYPYIISFAEDEAGELYFMSTGVPSATAARGVIYKVIDPSRRAPPGKCKIHPAQVTVKSHLIPFVPKETPVPSTVSDTFQRPETQQVSIDLQVQGILFNRTFSQVPGSGEATPGGCSLRQGVARRV", "length": 802, "header": "tr|A0A9J7FZM4-1|A0A9J7FZM4_CRIGR Computationally mapped isoform of HHIP-like protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Hhipl1 PE=3 SV=1 CANONICAL=A0A9J7G3X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6/entry#A0A9J7G3X6-1", "sequence": { "sequence": "MYCEVAASSLLPRAQTSLLVRSRATPPVSCTTPPFLNTLLRFLSGSEMGGTTNQESLLWALEFLLLGGQVGSVPRQEAETPRCNRATRLPRGQATALVGKARGQEEGAARRAGVRLCPASPVLQECSQAEIAWRMAGRRAVAGIGPGALLALRALLAAAHPQCLDFRPPFRPPQPLSFCVQYSSFGCCTAEQDAALARRFRALETRLDPGMWATCAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQICRGLFRHLSPDHELWALESNRAKLCRYLSLDDTDYCFPSLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHAGDGSHRFFVAEQVGLVWTYLPDLSRLEKPFLNVSQAVLTSPWEGDERGFLGLAFHPHFPHPSKLYVYYSVGVGYREWIRISEFRVSEDDENTVDHGSERIILEIEEPASNHNGGQLLFGYDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRNERGPPYRIPPDNPFVDDPGARPEVYALGVRNMWRCSFDRGDPMSGTGRGRLFCGDVGQNKYEEVDLVERGRNYGWRAREGFECYDRKLCANASLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENPETGQWKYSEVCMGRGQTCAFPGLINNYYPYIISFAEDEAGELYFMSTGVPSATAARGVIYKVIDPSRRAPPGKCKIHPAQVTVKSHLIPFVPKERFIRTPESTPRPTARAPTKAPRRRRPTAAPPAPTLRPTKPARPTRRPGARKGGGRRRGRPSTAVPAPQNGSVRLVRPAGLSPGRGRVEVFVGGHWGTVCDDAWDTKAAAVVCRQLGFAHAVRAAKRAEFGEGRALPILLDDVRCAGSERNLLECAHAGVGTHNCKHEEDAGVECSHQDPDL", "length": 925, "header": "tr|A0A9J7G3X6-1|A0A9J7G3X6_CRIGR Isoform 1 of HHIP-like protein 1 isoform X6 OS=Cricetulus griseus OX=10029 GN=Hhipl1 PE=3 SV=1 CANONICAL=A0A9J7G3X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H022-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6/entry#A0A9J7H022-1", "sequence": { "sequence": "MAGRRAVAGIGPGALLALRALLAAAHPQCLDFRPPFRPPQPLSFCVQYSSFGCCTAEQDAALARRFRALETRLDPGMWATCAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQICRGLFRHLSPDHELWALESNRAKLCRYLSLDDTDYCFPSLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHAGDGSHRFFVAEQVGLVWTYLPDLSRLEKPFLNVSQAVLTSPWEGDERGFLGLAFHPHFPHPSKLYVYYSVGVGYREWIRISEFRVSEDDENTVDHGSERIILEIEEPASNHNGGQLLFGYDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRNERGPPYRIPPDNPFVDDPGARPEVYALGVRNMWRCSFDRGDPMSGTGRGRLFCGDVGQNKYEEVDLVERGRNYGWRAREGFECYDRKLCANASLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENPETGQWKYSEVCMGRGQTCAFPGLINNYYPYIISFAEDEAGELYFMSTGVPSATAARGVIYKVIDPSRRAPPGKCKIHPAQVTVKSHLIPFVPKERFIRTPESTPRPTARAPTKAPRRRRPTAAPPAPTLRPTKPARPTRRPGARKGGGRRRGRPSTAVPAPQNGSVRLVRPAGLSPGRGRVEVFVGGHWGTVCDDAWDTKAAAVVCRQLGFAHAVRAAKRAEFGEGRALPILLDDVRCAGSERNLLECAHAGVGTHNCKHEEDAGVECSHQDPDL", "length": 791, "header": "tr|A0A9J7H022-1|A0A9J7H022_CRIGR Computationally mapped isoform of HHIP-like protein 1 isoform X9 OS=Cricetulus griseus OX=10029 GN=Hhipl1 PE=3 SV=1 CANONICAL=A0A9J7G3X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6/entry#A0A9J7JNE6-1", "sequence": { "sequence": "MHAPGKSRCCSPRWQVPGCGVLRIPGPRGSVYVCSWGEAEIAWRMAGRRAVAGIGPGALLALRALLAAAHPQCLDFRPPFRPPQPLSFCVQYSSFGCCTAEQDAALARRFRALETRLDPGMWATCAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQICRGLFRHLSPDHELWALESNRAKLCRYLSLDDTDYCFPSLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHAGDGSHRFFVAEQVGLVWTYLPDLSRLEKPFLNVSQAVLTSPWEGDERGFLGLAFHPHFPHPSKLYVYYSVGVGYREWIRISEFRVSEDDENTVDHGSERIILEIEEPASNHNGGQLLFGYDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRNERGPPYRIPPDNPFVDDPGARPEVYALGVRNMWRCSFDRGDPMSGTGRGRLFCGDVGQNKYEEVDLVERGRNYGWRAREGFECYDRKLCANASLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENPETGQWKYSEVCMGRGQTCAFPGLINNYYPYIISFAEDEAGELYFMSTGVPSATAARGVIYKVIDPSRRAPPGKCKIHPAQVTVKSHLIPFVPKERFIRTPESTPRPTARAPTKAPRRRRPTAAPPAPTLRPTKPARPTRRPGARKGGGRRRGRPSTAVPAPQNGSVRLVRPAGLSPGRGRVEVFVGGHWGTVCDDAWDTKAAAVVCRQLGFAHAVRAAKRAEFGEGRALPILLDDVRCAGSERNLLECAHAGVGTHNCKHEEDAGVECSHQDPDL", "length": 835, "header": "tr|A0A9J7JNE6-1|A0A9J7JNE6_CRIGR Computationally mapped isoform of HHIP-like protein 1 isoform X8 OS=Cricetulus griseus OX=10029 GN=Hhipl1 PE=3 SV=1 CANONICAL=A0A9J7G3X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQ88-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6/entry#A0A9J7JQ88-1", "sequence": { "sequence": "MYCEVAASSLLPRAQTSLLVRSRATPPVSCTTPPFLNTLLRFLSGSEMGGTTNQESLLWALEFLLLGGQVGSVPRQEAETPRCNRATRLPRGQATALVGKARGQEEGAARRAGVRLCPASPVLQECSQAEIAWRMAGRRAVAGIGPGALLALRALLAAAHPQCLDFRPPFRPPQPLSFCVQYSSFGCCTAEQDAALARRFRALETRLDPGMWATCAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQICRGLFRHLSPDHELWALESNRAKLCRYLSLDDTDYCFPSLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHAGDGSHRFFVAEQVGLVWTYLPDLSRLEKPFLNVSQAVLTSPWEGDERGFLGLAFHPHFPHPSKLYVYYSVGVGYREWIRISEFRVSEDDENTVDHGSERIILEIEEPASNHNGGQLLFGYDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRNERGPPYRIPPDNPFVDDPGARPEVYALGVRNMWRCSFDRGDPMSGTGRGRLFCGDVGQNKYEEVDLVERGRNYGWRAREGFECYDRKLCANASLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENPETGQWKYSEVCMGRGQTCAFPGLINNYYPYIISFAEDEAGELYFMSTGVPSATAARGVIYKVIDPSRS", "length": 718, "header": "tr|A0A9J7JQ88-1|A0A9J7JQ88_CRIGR Computationally mapped isoform of HHIP-like protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Hhipl1 PE=3 SV=1 CANONICAL=A0A9J7G3X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6/entry#A0A9J7JRD2-1", "sequence": { "sequence": "MYCEVAASSLLPRAQTSLLVRSRATPPVSCTTPPFLNTLLRFLSGSEMGGTTNQESLLWALEFLLLGGQVGSVPRQEAETPRCNRATRLPRGQATALVGKARGQEEGAARRAGVRLCPASPVLQECSQAEIAWRMAGRRAVAGIGPGALLALRALLAAAHPQCLDFRPPFRPPQPLSFCVQYSSFGCCTAEQDAALARRFRALETRLDPGMWATCAGYALDLLCQECSPYAAHLYDAEDPATPLRTVPGLCEDYCLDMWQICRGLFRHLSPDHELWALESNRAKLCRYLSLDDTDYCFPSLLVNENLNSNLGRVVADAKGCLQLCLEEVANGLRNPVAMVHAGDGSHRFFVAEQVGLVWTYLPDLSRLEKPFLNVSQAVLTSPWEGDERGFLGLAFHPHFPHPSKLYVYYSVGVGYREWIRISEFRVSEDDENTVDHGSERIILEIEEPASNHNGGQLLFGYDGYLYIFTGDGGMAGDPFGKFGNAQNKSALLGKVLRIDVDRNERGPPYRIPPDNPFVDDPGARPEVYALGVRNMWRCSFDRGDPMSGTGRGRLFCGDVGQNKYEEVDLVERGRNYGWRAREGFECYDRKLCANASLDDVLPIFAYPHKLGKSVTGGYVYRGCEYPNLNGLYIFGDFMSGRLMSLRENPETGQWKYSEVCMGRGQTCAFPGLINNYYPYIISFAEDEAGELYFMSTGVPSATAARGVIYKVIDPSRRAPPGKCKIHPAQVTVKSHLIPFVPKEKTGDPASVN", "length": 753, "header": "tr|A0A9J7JRD2-1|A0A9J7JRD2_CRIGR Computationally mapped isoform of HHIP-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Hhipl1 PE=3 SV=1 CANONICAL=A0A9J7G3X6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769577", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769577", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G3X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X6" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 816, "end_pos": 919, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 374, "end_pos": 376 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 813, "end_pos": 815 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G567-1", "uniprot_ac": "A0A9J7G567", "uniprot_id": "A0A9J7G567_CRIGR", "mass": { "chemical_mass": 66905.0, "monoisotopic_mass": 66905.0 }, "refseq": { "ac": "XP_027273128", "name": "torsin-1A-interacting protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273128" }, "gene_names": [ { "name": "Tor1aip1", "type": "recommended", "evidence": [ { "id": "A0A9J7G567", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567" } ] }, { "name": "Tor1aip1", "type": "synonym", "evidence": [ { "id": "XP_027273128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273128" } ] } ], "protein_names": [ { "name": "Torsin-1A-interacting protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7G567", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567/entry#names_and_taxonomy" } ] }, { "name": "Lamina-associated polypeptide 1B", "type": "synonym", "evidence": [ { "id": "A0A9J7G567", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567/entry#names_and_taxonomy" } ] }, { "name": "torsin-1A-interacting protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027273128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273128" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273128", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273128" } ] }, { "annotation": "Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G567", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567#function" }, { "database": "UniProtKB", "id": "ARBA00037580", "url": "https://www.uniprot.org/uniprotkb/ARBA00037580#function" }, { "database": "UniProtKB", "id": "A0A9J7G0N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N4#function" }, { "database": "UniProtKB", "id": "A0A9J7G0X5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0X5#function" }, { "database": "UniProtKB", "id": "A0A9J7JP23", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP23#function" }, { "database": "UniProtKB", "id": "A0A9J7K9H9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H9#function" }, { "database": "UniProtKB", "id": "A0A9J7H1G3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1G3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G567", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tor1aip1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567", "locus": {} } ], "crossref": [ { "id": "A0A9J7G567", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G567", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751143", "url": "https://www.ncbi.nlm.nih.gov/gene/100751143", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751143", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751143", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G567", "url": "https://www.orthodb.org/?gene=A0A9J7G567", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18843", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18843", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18843:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18843:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05609", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05609", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273128", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273128", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G0N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0X5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G567", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G567-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1G3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP23", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP23-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9H9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGDRRLTQAPGGGWAIDVTPRAPIREPRRRLAPQNGDSSDAPAYGTHPSRHGRREVRFSEEPPEVYGDFEPPVTKERSPGGRRTPPEKFRPDSAKEEVRESAYNLRSRPRRRRGPQEAEEMKTRRSTRLEQTSQQPQPQLSPATSRRGLRDSQSSEDEPSSSQTVTSQTASKRTVRTPDASMMSEDPISNLCRPPLRSPRSDSTYKTNGNSKMSEIEAVSTQPVHFSEEGETEDDLESSYSDTTVKVRSRNSVESRDEATRSSSYCQESSWRLPQSQDFTAHENQPSVLNSRCQKNAQEWVEQVIRMRTRLLQNNIQESEFGNQSPSTSGQPEPAEQPDNEPSVNRKRWLLGLVVSLAIGLLWFFYTPAVQTTAVQEFQNQMKQLQSKYQSQDEKLWKRGTTFLERHLNSSVPRPQPAILLLTAAQDAKEVLKCLSEQIADAYSSFRSVRAIRIDGAGKAAQDSDLVKQEVDQELSNGFRNGQNAAVVHRFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEKTLKASLGLKEIEEKVRDFLKVKFTNSNKASSYNHMDPDKLNGLWSRISHVVLPVQPENALKGGSCL", "length": 594, "header": "tr|A0A9J7G567-1|A0A9J7G567_CRIGR Isoform 1 of Torsin-1A-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Tor1aip1 PE=3 SV=1 CANONICAL=A0A9J7G567-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G0N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567/entry#A0A9J7G0N4-1", "sequence": { "sequence": "MEGDRRLTQAPGGGWAIDVTPRAPIREPRRRLAPQNGDSSDAPAYGTHPSRHGRREVRFSEEPPEVYGDFEPPVTKERSPGGRRTPPEKFRPDSAKEEVRESAYNLRSRPRRRRGPQEAEEMKTRRSTRLEQTSQQPQPQLSPATSRRGLRDSQSSEDEPSSSQTVTSQTASKRTVRTPDASMMSEDPISNLCRPPLRSPRSDSTYKTNGNSKMSEIEAVSTQPVHFSEEGETEDDLESSYSDTTVKVRSRNSVESRDEATRSSSYCQESSWRLPQSQDFTAHENQPSVLNSRCQKNAQEWVEQVIRMRTRLLQNNIQESEFGNQSPSTSGQQPAEQPDNEPSVNRKRWLLGLVVSLAIGLLWFFYTPAVQTTAVQEFQNQMKQLQSKYQSQDEKLWKRGTTFLERHLNSSVPRPQPAILLLTAAQDAKEVLKCLSEQIADAYSSFRSVRAIRIDGAGKAAQDSDLVKQEVDQELSNGFRNGQNAAVVHRFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEKTLKASLGLKEIEEKVRDFLKVKFTNSNKASSYNHMDPDKLNGLWSRISHVVLPVQPENALKGGSCL", "length": 593, "header": "tr|A0A9J7G0N4-1|A0A9J7G567_CRIGR Computationally mapped isoform of Torsin-1A-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Tor1aip1 PE=3 SV=1 CANONICAL=A0A9J7G567-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G0X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567/entry#A0A9J7G0X5-1", "sequence": { "sequence": "MEGDRRLTQAPGGGWAIDVTPRAPIREPRRRLAPQNGDSSDAPAYGTHPSRHGRREVRFSEEPPEVYGDFEPPVTKERSPGGRRTPPEKFRPDSAKEEVRESAYNLRSRPRRRRGPQEAEEMKTRRSTRLEQTSQQPQPQLSPATSRRGLRDSQSSEDEPSSSQTVTSQTASKRTVRTPDASMMSEDPISNLCRPPLRSPRSDSTYKTNGNSKMSEIEAVSTQPVHFSEEGETEDDLESSYSDTTVKVRSRNSVESRGQDFTAHENQPSVLNSRCQKNAQEWVEQVIRMRTRLLQNNIQESEFGNQSPSTSGQQPAEQPDNEPSVNRKRWLLGLVVSLAIGLLWFFYTPAVQTTAVQEFQNQMKQLQSKYQSQDEKLWKRGTTFLERHLNSSVPRPQPAILLLTAAQDAKEVLKCLSEQIADAYSSFRSVRAIRIDGAGKAAQDSDLVKQEVDQELSNGFRNGQNAAVVHRFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEKTLKASLGLKEIEEKVRDFLKVKFTNSNKASSYNHMDPDKLNGLWSRISHVVLPVQPENALKGGSCL", "length": 574, "header": "tr|A0A9J7G0X5-1|A0A9J7G567_CRIGR Computationally mapped isoform of Torsin-1A-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Tor1aip1 PE=3 SV=1 CANONICAL=A0A9J7G567-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G567-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567/entry#A0A9J7G567-1", "sequence": { "sequence": "MEGDRRLTQAPGGGWAIDVTPRAPIREPRRRLAPQNGDSSDAPAYGTHPSRHGRREVRFSEEPPEVYGDFEPPVTKERSPGGRRTPPEKFRPDSAKEEVRESAYNLRSRPRRRRGPQEAEEMKTRRSTRLEQTSQQPQPQLSPATSRRGLRDSQSSEDEPSSSQTVTSQTASKRTVRTPDASMMSEDPISNLCRPPLRSPRSDSTYKTNGNSKMSEIEAVSTQPVHFSEEGETEDDLESSYSDTTVKVRSRNSVESRDEATRSSSYCQESSWRLPQSQDFTAHENQPSVLNSRCQKNAQEWVEQVIRMRTRLLQNNIQESEFGNQSPSTSGQPEPAEQPDNEPSVNRKRWLLGLVVSLAIGLLWFFYTPAVQTTAVQEFQNQMKQLQSKYQSQDEKLWKRGTTFLERHLNSSVPRPQPAILLLTAAQDAKEVLKCLSEQIADAYSSFRSVRAIRIDGAGKAAQDSDLVKQEVDQELSNGFRNGQNAAVVHRFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEKTLKASLGLKEIEEKVRDFLKVKFTNSNKASSYNHMDPDKLNGLWSRISHVVLPVQPENALKGGSCL", "length": 594, "header": "tr|A0A9J7G567-1|A0A9J7G567_CRIGR Isoform 1 of Torsin-1A-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Tor1aip1 PE=3 SV=1 CANONICAL=A0A9J7G567-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567/entry#A0A9J7H1G3-1", "sequence": { "sequence": "MEGDRRLTQAPGGGWAIDVTPRAPIREPRRRLAPQNGDSSDAPAYGTHPSRHGRREVRFSEEPPEVYGDFEPPVTKERSPGGRRTPPEKFRPDSAKEEVRESAYNLRSRPRRRRGPQEAEEMKTRRSTRLEQTSQQPQPQLSPATSRRGLRDSQSSEDEPSSSQTVTSQTASKRTVRTPDASMMSEDPISNLCRPPLRSPRSEAVSTQPVHFSEEGETEDDLESSYSDTTVKVRSRNSVESRDEATRSSSYCQESSWRLPQSQDFTAHENQPSVLNSRCQKNAQEWVEQVIRMRTRLLQNNIQESEFGNQSPSTSGQQPAEQPDNEPSVNRKRWLLGLVVSLAIGLLWFFYTPAVQTTAVQEFQNQMKQLQSKYQSQDEKLWKRGTTFLERHLNSSVPRPQPAILLLTAAQDAKEVLKCLSEQIADAYSSFRSVRAIRIDGAGKAAQDSDLVKQEVDQELSNGFRNGQNAAVVHRFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEKTLKASLGLKEIEEKVRDFLKVKFTNSNKASSYNHMDPDKLNGLWSRISHVVLPVQPENALKGGSCL", "length": 578, "header": "tr|A0A9J7H1G3-1|A0A9J7H1G3_CRIGR Computationally mapped isoform of Torsin-1A-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Tor1aip1 PE=3 SV=1 CANONICAL=A0A9J7G567-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JP23-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567/entry#A0A9J7JP23-1", "sequence": { "sequence": "MEGDRRLTQAPGGGWAIDVTPRAPIREPRRRLAPQNGDSSDAPAYGTHPSRHGRREVRFSEEPPEVYGDFEPPVTKERSPGGRRTPPEKFRPDSAKEEVRESAYNLRSRPRRRRGPQEAEEMKTRRSTRLEQTSQQPQPQLSPATSRRGLRDSQSSEDEPSSSQTVTSQTASKRTVRTPDASMMSEDPISNLCRPPLRSPRSDSTYKTNGNSKMSEIEAVSTQPVHFSEEGETEDDLESSYSDTTVKVRSRNSVESRGQDFTAHENQPSVLNSRCQKNAQEWVEQVIRMRTRLLQNNIQESEFGNQSPSTSGQPEPAEQPDNEPSVNRKRWLLGLVVSLAIGLLWFFYTPAVQTTAVQEFQNQMKQLQSKYQSQDEKLWKRGTTFLERHLNSSVPRPQPAILLLTAAQDAKEVLKCLSEQIADAYSSFRSVRAIRIDGAGKAAQDSDLVKQEVDQELSNGFRNGQNAAVVHRFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEKTLKASLGLKEIEEKVRDFLKVKFTNSNKASSYNHMDPDKLNGLWSRISHVVLPVQPENALKGGSCL", "length": 575, "header": "tr|A0A9J7JP23-1|A0A9J7JP23_CRIGR Computationally mapped isoform of Torsin-1A-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Tor1aip1 PE=3 SV=1 CANONICAL=A0A9J7G567-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567/entry#A0A9J7K9H9-1", "sequence": { "sequence": "MEGDRRLTQAPGGGWAIDVTPRAPIREPRRRLAPQNGDSSDAPAYGTHPSRHGRREVRFSEEPPEVYGDFEPPVTKERSPGGRRTPPEKFRPDSAKEEVRESAYNLRSRPRRRRGPQEAEEMKTRRSTRLEQTSQQPQPQLSPATSRRGLRDSQSSEDEPSSSQTVTSQTASKRTVRTPDASMMSEDPISNLCRPPLRSPRSEAVSTQPVHFSEEGETEDDLESSYSDTTVKVRSRNSVESRDEATRSSSYCQESSWRLPQSQDFTAHENQPSVLNSRCQKNAQEWVEQVIRMRTRLLQNNIQESEFGNQSPSTSGQPEPAEQPDNEPSVNRKRWLLGLVVSLAIGLLWFFYTPAVQTTAVQEFQNQMKQLQSKYQSQDEKLWKRGTTFLERHLNSSVPRPQPAILLLTAAQDAKEVLKCLSEQIADAYSSFRSVRAIRIDGAGKAAQDSDLVKQEVDQELSNGFRNGQNAAVVHRFESLPAGSTLIFYKYCDHENAAFKDVALVLTVLLEEKTLKASLGLKEIEEKVRDFLKVKFTNSNKASSYNHMDPDKLNGLWSRISHVVLPVQPENALKGGSCL", "length": 579, "header": "tr|A0A9J7K9H9-1|A0A9J7K9H9_CRIGR Computationally mapped isoform of Torsin-1A-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Tor1aip1 PE=3 SV=1 CANONICAL=A0A9J7G567-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0N4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751143", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751143", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATPase activator activity", "id": "GO:0001671", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001671", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G567", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G567", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nuclear membrane organization", "id": "GO:0071763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071763", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G567", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G567", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567" }, { "id": "PF05609", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05609" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Torsin-1A-interacting protein 1/2 AAA+ activator", "eco_id": "ECO_0000259", "start_pos": 368, "end_pos": 594, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G567", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G567" }, { "id": "PF20443", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20443" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Torsin-1A-interacting protein 1/2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 357, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 324, "end_pos": 326 }, { "start_pos": 410, "end_pos": 412 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G5C5-1", "uniprot_ac": "A0A9J7G5C5", "uniprot_id": "A0A9J7G5C5_CRIGR", "mass": { "chemical_mass": 359252.0, "monoisotopic_mass": 359252.0 }, "refseq": { "ac": "XP_027273244", "name": "abnormal spindle-like microcephaly-associated protein isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273244" }, "gene_names": [ { "name": "Aspm", "type": "recommended", "evidence": [ { "id": "A0A9J7G5C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5C5" } ] }, { "name": "Aspm", "type": "synonym", "evidence": [ { "id": "XP_027273244", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273244" } ] } ], "protein_names": [ { "name": "Abnormal spindle-like microcephaly-associated protein isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7G5C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5C5/entry#names_and_taxonomy" } ] }, { "name": "abnormal spindle-like microcephaly-associated protein isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027273244", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273244" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273244", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273244" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5C5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Aspm", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5C5", "locus": {} } ], "crossref": [ { "id": "cd21223", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21223", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23767", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23767", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764564", "url": "https://www.ncbi.nlm.nih.gov/gene/100764564", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031549", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031549", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764564", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764564", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G5C5", "url": "https://www.orthodb.org/?gene=A0A9J7G5C5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22706:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22706:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273244", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273244", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G0U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5C5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATRQAAYNREESGRRVHRDPAPAAAESPPPVLPLSHFCAAPFLCFGDVRVGASRTRSLVLQNPHEEPLLVELSLLRAASQGFSVVPSRCELKPKEKVTVSVTWAPLKEGRVREIVTFLVNDFLKHQAILLGNAEEHRKKKRSRWNTIKKIPNSSKHNKGTSKSQNCNEAFTISQNVGRIRSPLQACENLAMSECCSPTENSSLSLEENKIPTSSVTPVKESQNETCLATPFLSSTAYSSLPGSKDAHVKVQDASISDDCNFNEELTNQTFLNPLSISDQIEGKGQHPLAPNYSSPLNIMQSQIHFLSPDSFVNNSYASDNGLGLVRNVLSETFRKDNSEPLCSESQKVGEVCQTIISPESFLNDNYGLKKTLKSDSVNPILAPQFSKDNMVHIGQQTCKLSTLSNKTSQDWRISEGLAYNLECLHSETPKVRFEKQNLEEIMSPNPGFTKHPSISNASLYNQSKQPKRRPILSATVTKKKPTNGREKLPEIDKPNAKRCLKGLVGQCGEEMTNLKEKSCHSHLPVVEPVISKPQGYKSESTPLTTISISRKRKSSGNMADANGKLAVTEHVDVCEIKRVHFSPLESTSSTTSRTKKKETFTSEHTGNWEKASLMKKTDSLVLKTPLSKTKKRTRPIVAVAQSHLTFIKPLKAAIPRHPMPFAAKNMFYDERWKEKQEQGFTWWLNYILTPDDFTVKTNVSEVNAATLVLGVENQHKVSVPKAPTKDEVSLRAYTASCRINRLRRTACSLFTSDKMVKAIKKLEIEIEVGRLIVRKDRHLWKDIGQRQKVLNWLLSYNPLWLRIGLETVYGELIPLADNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPLLFRDGHEAALSKFTLKKLLLLICFLDYAKISRLIDHDPCLFCKDAEFKASKELLLAFSRDFLRGEGDLSRHLSLLGLPVSHIQTPLDEFDFAVTNIAVDLQCGVRLVRTMELLTQNWNLSKKLRIPAISRVQKMHNVDIVLQVLKSRGVQLTDEHGNTILSKDIVDRHREKTLGLLWKIAFAFQVNISLNLDQLKEEIDFLKCTHKIKRAMSDISCHSRAGADKQKDKRNSGPFEHYGDSVKLLMDWVNAVCAFYDKQVENFTVSFSDGRVLCYLIHHYHPCHVPFDAICQRTTQSVACAQTGSVVLNSSSESDGSCLDLSLEALTHENTPDLYRELLENEKSNFHLVRSAARDLGGIPAMIHHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKRDLKHHQERDKAARIIQSVVLSFLTRRRLQKWTSAALVIQKCWRRVLAQRQLQMLKNEKLAKLQSKSASVIQAYWRRYFTRKQFLKLKYYSVILQSRIRMKIALTAYKRYLWATVTIQRRWRACLRSKQDQQRFKMLKSSALIIQCMFRRWKRRKLQLQTQAAVTLQRAFREWHLRKQARERSAVVIQSWYRRHRQVQKYTHIRSCVVAIQRRFRCFQAQKLYKKRKVAVLTLQKHYRAYRKGKLARTDYLQKQAAAILLQAAFRRMKARNSHREIRAACVLQSYWRMRQERVGFLNLKKIVIRLQAHIRRHQQVQKYKRIKEAAIIIQTRFRASVSARKALVSYQKTRSSVIVLQSAYRGMQARKMFSHTLKSVVKIQSYYRAYTSRKKFQSFRKATIKLQSIVRMKQTRKQYLHLRAAVLFIQQWYRFQKLAAQKRKEYIQVCESCIKLQAYFRGCLVRRQMRLQSKAAISLQSYFRMRKTRQQYLKMCKAAVVIQNFYRAYKAQVSQRKKFLQVKGAAVCLQAAFRGHKARQVLKQQSTAAVTIQRVFRGYSQRMKFQTVLQSAVKIQRWYRAHKIASDMRTQFLTTGVAVVSLQSAYPGWRVGQQLRRKHEAAVKIQSTFRMLLAMKRFKLLRTAAVVIQQHARARAAAKRQRLEYLELRRAALVFQATWKGKTLRRQIERQHGCAALIQSYYRMHVQRRKWKMMRTAALQIQVFYRTYKVGQEQRRLYLETKAAIVILQSAYRGMKVRKRLKECSKAAVTLQSKFRAYRARKKYTNYRASAIIIQRWYRNIKITARQHQDYLHLKKAAVKVQAVYRGVRVRRHIQHMHMAATLIKAMFKMHQSRARYHGMRRAAVVIQRRYRAYCLGKIQREKYLSTLQAIRTLQAGVRGARVRQTVREMRIAATLIQSHFRRYRQQTYFHRLRKVTKMVQQRFRAVRERNIQFHRYHRLRRSVILIQAAFRGLRARRHLKAMHRAAVLIQRRYRTLLMRRKFLSLRKSVICIQRQFRANLHTKYHRQFLLEKAVVRIQSSYKGWAVRKRMQKMHRAATVIQATFRRHRAHVRYQGLKQASVVIQRQRHAAVILQAAFRGMKARSQLKTMHSSATLIQSKFRALVVRRRFIALRKAAIFVQRKYRAAIYTKRELHQFLQLQKAAITIQSSYRRLLVKKKLQEMHRAAVLIQATFRMHRTYVRFHTWKRASIIIQQHYRTYRTMKLQREKLIRHIGHWDSAVAAHDGMKASQLLKEKHSAAVIIQSTYRMHRQRRFYQQLRWAAKVIQEKYRANKERQQALLLNACKEETTLMQMHFQDLNTTKQIQDQHEAAMIIQKHFRAFKARRHVECERGFQAGWRNYKAKKYLSKVEAACRIQAWYRCWRARKRYLALVKAAKIIQGYFCAKMERMRFLKMRSSAIIIQRKWRSKLSARLAHEKLILKVSELKAKIQLLHFTAAAYYHLCALRIQRAYRRHVAARKAQEHIDAVISVQRWFRRRLQQKRCIEQYRKIIKTEHEVQECRQQQSRAASVIQKAVRHFLLRRRQEKLNSSATKIQAWWRGYSWRKKNDGTKIKAIRLSLRAVNRNVDEENKLYRRTERALHHLLTYKHLSAILDALKHLEVVTRLSPLCCENMAESGAISTIFVVIRSCNRSVPCMEVVGYAVQVLLNVAKYEKTTSAVYDAENCVDTLLELLQVYREKPGDRLSEKSASIFTRTCCLLAVLLKTEHCASDVQSRSKVIDRIYRLYKLKVPKHKVHMERLFDKQKQNPCIGFPFTPASSVKTRIVSRFQPQWVLRRDNMEEITNSLQAIQLVMDTLGIPYQ", "length": 3078, "header": "tr|A0A9J7G5C5-1|A0A9J7G5C5_CRIGR Isoform 1 of Abnormal spindle-like microcephaly-associated protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Aspm PE=4 SV=1 CANONICAL=A0A9J7G5C5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G0U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5C5/entry#A0A9J7G0U9-1", "sequence": { "sequence": "MATRQAAYNREESGRRVHRDPAPAAAESPPPVLPLSHFCAAPFLCFGDVRVGASRTRSLVLQNPHEEPLLVELSLLRAASQGFSVVPSRCELKPKEKVTVSVTWAPLKEGRVREIVTFLVNDFLKHQAILLGNAEEHRKKKRSRWNTIKKIPNSSKHNKGTSKSQNCNEAFTISQNVGRIRSPLQACENLAMSECCSPTENSSLSLEENKIPTSSVTPVKESQNETCLATPFLSSTAYSSLPGSKDAHVKVQDASISDDCNFNEELTNQTFLNPLSISDQIEGKGQHPLAPNYSSPLNIMQSQIHFLSPDSFVNNSYASDNGLGLVRNVLSETFRKDNSEPLCSESQKVGEVCQTIISPESFLNDNYGLKKTLKSDSVNPILAPQFSKDNMVHIGQQTCKLSTLSNKTSQDWRISEGLAYNLECLHSETPKVRFEKQNLEEIMSPNPGFTKHPSISNASLYNQSKQPKRRPILSATVTKKKPTNGREKLPEIDKPNAKRCLKGLVGQCGEEMTNLKEKSCHSHLPVVEPVISKPQGYKSESTPLTTISISRKRKSSGNMADANGKLAVTEHVDVCEIKRVHFSPLESTSSTTSRTKKKETFTSEHTGNWEKASLMKKTDSLVLKTPLSKTKKRTRPIVAVAQSHLTFIKPLKAAIPRHPMPFAAKNMFYDERWKEKQEQGFTWWLNYILTPDDFTVKTNVSEVNAATLVLGVENQHKVSVPKAPTKDEVSLRAYTASCRINRLRRTACSLFTSDKMVKAIKKLEIEIEVGRLIVRKDRHLWKDIGQRQKVLNWLLSYNPLWLRIGLETVYGELIPLADNSDVTGLAMFILNRLLWNPDIAAEYRHPTVPLLFRDGHEAALSKFTLKKLLLLICFLDYAKISRLIDHDPCLFCKDAEFKASKELLLAFSRDFLRGEGDLSRHLSLLGLPVSHIQTPLDEFDFAVTNIAVDLQCGVRLVRTMELLTQNWNLSKKLRIPAISRVQKMHNVDIVLQVLKSRGVQLTDEHGNTILSKDIVDRHREKTLGLLWKIAFAFQVNISLNLDQLKEEIDFLKCTHKIKRAMSDISCHSRAGADKQKDKRNSGPFEHYGDSVKLLMDWVNAVCAFYDKQVENFTVSFSDGRVLCYLIHHYHPCHVPFDAICQRTTQSVACAQTGSVVLNSSSESDGSCLDLSLEALTHENTPDLYRELLENEKSNFHLVRSAARDLGGIPAMIHHSDMSNTIPDEKVVITYLSFLCARLLDLRKEIRAARLIQTTWRKYKLKRDLKHHQERDKAARIIQSVVLSFLTRRRLQKWTSAALVIQKCWRRVLAQRQLQMLKNEKLAKLQSKSASVIQAGWRNYKAKKYLSKVEAACRIQAWYRCWRARKRYLALVKAAKIIQGYFCAKMERMRFLKMRSSAIIIQRKWRSKLSARLAHEKLILKVSELKAKIQLLHFTAAAYYHLCALRIQRAYRRHVAARKAQEHIDAVISVQRWFRRRLQQKRCIEQYRKIIKTEHEVQECRQQQSRAASVIQKAVRHFLLRRRQEKLNSSATKIQAWWRGYSWRKKNDGTKIKAIRLSLRAVNRNVDEENKLYRRTERALHHLLTYKHLSAILDALKHLEVVTRLSPLCCENMAESGAISTIFVVIRSCNRSVPCMEVVGYAVQVLLNVAKYEKTTSAVYDAENCVDTLLELLQVYREKPGDRLSEKSASIFTRTCCLLAVLLKTEHCASDVQSRSKVIDRIYRLYKLKVPKHKVHMERLFDKQKQNPCIGFPFTPASSVKTRIVSRFQPQWVLRRDNMEEITNSLQAIQLVMDTLGIPYQ", "length": 1800, "header": "tr|A0A9J7G0U9-1|A0A9J7G5C5_CRIGR Computationally mapped isoform of Abnormal spindle-like microcephaly-associated protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Aspm PE=4 SV=1 CANONICAL=A0A9J7G5C5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G5C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5C5/entry#A0A9J7G5C5-1", "sequence": { "sequence": 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"length": 3078, "header": "tr|A0A9J7G5C5-1|A0A9J7G5C5_CRIGR Isoform 1 of Abnormal spindle-like microcephaly-associated protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Aspm PE=4 SV=1 CANONICAL=A0A9J7G5C5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0U9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764564", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764564", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5C5" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5C5", "url": 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"tRNA (32-2'-O)-methyltransferase regulator THADA", "type": "recommended", "evidence": [ { "id": "A0A9J7G4P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3/entry#names_and_taxonomy" } ] }, { "name": "thyroid adenoma-associated protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027273727", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273727" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273727" } ] }, { "annotation": "Together with methyltransferase FTSJ1, methylates the 2'-O-ribose of nucleotides at position 32 of the anticodon loop of substrate tRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K4#function" }, { "database": "UniProtKB", "id": "ARBA00035625", "url": "https://www.uniprot.org/uniprotkb/ARBA00035625#function" }, { "database": "UniProtKB", "id": "A0A9J7G3H0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H0#function" }, { "database": "UniProtKB", "id": "A0A9J7G4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3#function" }, { "database": "UniProtKB", "id": "A0A9J7JST9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JST9#function" }, { "database": "UniProtKB", "id": "A0A8C2MLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MLJ5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Thada", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3", "locus": {} } ], "crossref": [ { "id": "100759859", "url": "https://www.ncbi.nlm.nih.gov/gene/100759859", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759859", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759859", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MLJ5", "url": "https://www.orthodb.org/?gene=A0A8C2MLJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G4P3", "url": "https://www.orthodb.org/?gene=A0A9J7G4P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14387", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14387", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14387:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14387:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25150", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25150", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273727", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MLJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MLJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MLJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MLJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3H0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JST9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JST9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JST9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JST9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVKKKREVQVAAVTVCHQDLETLRSFADVEGTNLASLLLHCVQLTDGVSQIQSVKQIVPLLEKVDKNGVCDPATQSCLDILAGIYFSLALKNPLKKVLASSLNGLPEFFLTEATHSFTSHLQEELNTADLHSYRKVIDNISSCMENFNLGRSSVVNLLENVLQFLNKSLIEILEENRKFAGNHIVQTQLMNDLLVGIRVSMTLVQKVQGLQGDLCSEPGSPIWQTVCDLLSMFTRCLNDDDLLQTIQSTSGLAVILFVKTMFHPPEKLPGLISSLLLQSVDCTSIPEWFMNSCRSLCCADVSASTLLFLCQGTLAMLDWQDRSMGPSGEALLLDTVRVLFTLSSHMFMELDNHHHSQPQSAPIFLDGHGGVVGRQRIKESTLEMFLSRILASWTNSAIQILESSSPNLKASLNGDSSIARRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHQLTMGGADSVTDPFFLELTKSLLKLEWHIKGKYSCLGCLVESIGVEHILSIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKCQTVTNTWMDEWHETWVSPLLSILCGGNLDQKSYVIDYYLPRLLNYSPESLQYMVKILQASIDTETGSYNRRGALGALMACLRTARAHGHLQSATHAWEDLMCGTRIKQGLIHQHCQVRIDTLGLLCESNRSTEVVSIEEMQWVRFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSAPDSESGSSSERPPVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALSILGSVAEVFAVSEGNIQPVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMKLSSVTARQFQDAEKLQGLFQAALELSTSTKPYDCVTASYLLNLLIWQDALPASLTASQAQQLTHRAHGAAEKATVLERNTLVVIKCLMENLEDEISQAEDSLLQAASSFPMYGRVHCITRAFQKLPLNDLRLVSEWRPVVEGLLLLSYRLSAVVSPVIQSSSPEGLIPMDTDSESASRLQVILNEIQPRDTNAYFNQAKILKECDSFDLEDLSASVSNIDSSAEIKGKETKTCDVTAQMVLVCCWRSMKEVALLLGTLCQLLPMRPVPESSNGLLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSAVSLQKLPEQWLWNVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEPKKSKMDLLKITMKELISLALSVDGSKGTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSSLITRIFGVKRGKDELSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDTGKPDRHPSMFLLLLVLERLYPSPMDGTSSALSLAPFVPFIIRCGRSPIYRSREMAARALVPFITIDQIPSTLHALLDSLPNSTDQCFRQNHIHGTLLQVFHLLQAYVTDSRHRTNADFQHELSDITACTKAKLWLATRQNPCLVTRAVYIDILFLLTKCLDRPAESKQPALQSLGLQEDVRRIVLGSELVTGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQAIAIPLSFSRLLESSFPEVRLLTLDTLLERVMSSELEEKGPPPLLCSMGEDFLLLAMKENHPGCFCQVLKILYHMNPSEWLSQTEHCVHLSPKEFLIWTMDIASKDRSEIQSVALKLASKLIAHHVQTCEENKDSIAPELRQWVQLVVWSCGDHLPTASRLAAAEVLTSATPLFLTNPRPILELQDTLALWKCVLTLLQSEEQAVREAATEIVTVAMSQGNTCQSTAGGSHTGMEGSICDLQMRDPKARREFAFCQVNASVALALALAVLCDLLQQWDQLVPGLPILLGWLLGESDDPQYLMQSPHQGEDDYIFEKSEVNFWAETLTFVRYLCWQLFHLPCQSGQPYPHSQLCHLQTIASEKRHLVSELFRELPLSAEFLKTVEYTRLRIQEERSLAVLRLLAFLEGKEVLRAEDCPREWRQLMAPRTEASC", "length": 1995, "header": "tr|A0A9J7G4P3-1|A0A9J7G4P3_CRIGR Isoform 1 of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Cricetulus griseus OX=10029 GN=Thada PE=3 SV=1 CANONICAL=A0A9J7G4P3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MLJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3/entry#A0A8C2MLJ5-1", "sequence": { "sequence": "MGVKKKREVQVAAVTVCHQDLETLRSFADVEGTNLASLLLHCVQLTDGVSQIQSVKQIVPLLEKVDKNGVCDPATQSCLDILAGIYFSLALKNPLKKVLASSLNGLPEFFLTEATHSFTSHLQEELNTADLHSYRKVIDNISSCMENFNLGRSSVVNLLENVLQFLNKSLIEILEENRKFAGNHIVQTQLMNDLLVGIRVSMTLVQKVQGLQGDLCSEPGSPIWQTVCDLLSMFTRCLNDDDLLQTIQSTSGLAVILFVKTMFHPPEKLPGLISSLLLQSVDCTSIPEWFMNSCRSLCCADVSASTLLFLCQGTLAMLDWQDRSMGPSGEALLLDTVRVLFTLSSQIKESTLEMFLSRILASWTNSAIQILESSSPNLKASLNGDSSIARRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHQLTMGGADSVTDPFFLELTKSLLKLEWHIKGKYSCLGCLVESIGVEHILSIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKCQTVTNTWMDEWHETWVSPLLSILCGGNLDQKSYVIDYYLPRLLNYSPESLQYMVKILQASIDTETGSYNRRGALGALMACLRTARAHGHLQSATHAWEDLMCGTRIKQGLIHQHCQVRIDTLGLLCESNRSTEVVSIEEMQWVRFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSAPDSESGSSSERPPVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALSILGSVAEVFAVSEGNIQPVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMKLSSVTARQFQDAEKLQGLFQAALELSTSTKPYDCVTASYLLNLLIWQDALPASLTASQAQQLTHRAHGAAEKATVLERNTLVVIKCLMENLEDEISQAEDSLLQAASSFPMYGRVHCITRAFQKLPLNDLRLVSEWRPVVEGLLLLSYRLSAVVSPVIQSSSPEGLIPMDTDSESASRLQVILNEIQPRDTNAYFNQAKILKECDSFDLEDLSASVSNIDSSAEIKGKETKTCDVTAQMVLVCCWRSMKEVALLLGTLCQLLPMRPVPESSNGLLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSAVSLQKLPEQWLWNVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEPKKSKMDLLKITMKELISLALSVDGSKGTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSSLITRIFGVKRGKDELSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDTGKPDRHPSMFLLLLVLERLYPSPMDGTSSALSLAPFVPFIIRCGRSPIYRSREMAARALVPFITIDQIPSTLHALLDSLPNSTDQCFRQNHIHGTLLQVFHLLQAYVTDSRHRTNADFQHELSDITACTKAKLWLATRQNPCLVTRAVYIDILFLLTKCLDRPAESKQPALQSLGLQEDVRRIVLGSELVTGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQAIAIPLSFSRLLESSFPEVRLLTLDTLLERVMSSELEEKGPPPLLCSMGEDFLLLAMKENHPGCFCQVLKILYHMNPSEWLSQTEHCVHLSPKEFLIWTMDIASKDRSEIQSVALKLASKLIAHHVQTCEENKDSIAPELRQWVQLVVWSCGDHLPTASRLAAAEVLTSATPLFLTNPRPILELQDTLALWKCVLTLLQSEEQAVREAATEIVTVAMSQGNTCQSTEFAFCQVNASVALALALAVLCDLLQQWDQLVPGLPILLGWLLGESDDPQYLMQSPHQGEDDYIFEKSEVNFWAETLTFVRYLCWQLFHLPCQSGQPYPHSQLCHLQTIASEKRHLVSELFRELPLSAEFLKTVEYTRLRIQEERSLAVLRLLAFLEGKEVLRAEDCPREWRQLMAPRTEASC", "length": 1940, "header": "tr|A0A8C2MLJ5-1|A0A8C2MLJ5_CRIGR Computationally mapped isoform of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Cricetulus griseus OX=10029 GN=Thada PE=3 SV=1 CANONICAL=A0A9J7G4P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3/entry#A0A9J7G1K4-1", "sequence": { "sequence": "MGVKKKREVQVAAVTVCHQDLETLRSFADVEGTNLASLLLHCVQLTDGVSQIQSVKQIVPLLEKVDKNGVCDPATQSCLDILAGIYFSLALKNPLKKVLASSLNGLPEFFLTEATHSFTSHLQEELNTADLHSYRKVIDNISSCMENFNLGRSSVVNLLENVLQFLNKSLIEILEENRKFAGNHIVQTQLMNDLLVGIRVSMTLVQKVQGLQGDLCSEPGSPIWQTVCDLLSMFTRCLNDDDLLQTIQSTSGLAVILFVKTMFHPPEKLPGLISSLLLQSVDCTSIPEWFMNSCRSLCCADVSASTLLFLCQGTLAMLDWQDRSMGPSGEALLLDTVRVLFTLSSHMFMELDNHHHSQPQSAPIFLDGHGGVVGRQRIKESTLEMFLSRILASWTNSAIQILESSSPNLKASLNGDSSIARRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHQLTMGGADSVTDPFFLELTKSLLKLEWHIKGKYSCLGCLVESIGVEHILSIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKCQTVTNTWMDEWHETWVSPLLSILCGGNLDQKSYVIDYYLPRLLNYSPESLQYMVKILQASIDTETGSYNRRGALGALMACLRTARAHGHLQSATHAWEDLMCGTRIKQGLIHQHCQVRIDTLGLLCESNRSTEVVSIEEMQWVRFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSAPDSESGSSSERPPVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALSILGSVAEVFAVSEGNIQPVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMKLSSVTARQFQDAEKLQGLFQAALELSTSTKPYDCVTASYLLNLLIWQDALPASLTASQAQQLTHRAHGAAEKATVLERNTLVVIKCLMENLEDEISQAEDSLLQAASSFPMYGRVHCITRAFQKLPLNDLRLVSEWRPVVEGLLLLSYRLSAVVSPVIQSSSPEGLIPMDTDSESASRLQVILNEIQPRDTNAYFNQAKILKECDSFDLEDLSASVSNIDSSAEIKGKETKTCDVTAQMVLVCCWRSMKEVALLLGTLCQLLPMRPVPESSNGLLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSAVSLQKLPEQWLWNVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEPKKSKMDLLKITMKELISLALSVDGSKGTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSSLITRIFGVKRGKDELSKTNRCGRSPIYRSREMAARALVPFITIDQIPSTLHALLDSLPNSTDQCFRQNHIHGTLLQVFHLLQAYVTDSRHRTNADFQHELSDITACTKAKLWLATRQNPCLVTRAVYIDILFLLTKCLDRPAESKQPALQSLGLQEDVRRIVLGSELVTGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQAIAIPLSFSRLLESSFPEVRLLTLDTLLERVMSSELEEKGPPPLLCSMGEDFLLLAMKENHPGCFCQVLKILYHMNPSEWLSQTEHCVHLSPKEFLIWTMDIASKDRSEIQSVALKLASKLIAHHVQTCEENKDSIAPELRQWVQLVVWSCGDHLPTASRLAAAEVLTSATPLFLTNPRPILELQDTLALWKCVLTLLQSEEQAVREAATEIVTVAMSQGNTCQSTAGGSHTGMEGSICDLQMRDPKARREFAFCQVNASVALALALAVLCDLLQQWDQLVPGLPILLGWLLGESDDPQYLMQSPHQGEDDYIFEKSEVNFWAETLTFVRYLCWQLFHLPCQSGQPYPHSQLCHLQTIASEKRHLVSELFRELPLSAEFLKTVEYTRLRIQEERSLAVLRLLAFLEGKEVLRAEDCPREWRQLMAPRTEASC", "length": 1921, "header": "tr|A0A9J7G1K4-1|A0A9J7G4P3_CRIGR Computationally mapped isoform of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Cricetulus griseus OX=10029 GN=Thada PE=3 SV=1 CANONICAL=A0A9J7G4P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3/entry#A0A9J7G3H0-1", "sequence": { "sequence": "MGVKKKREVQVAAVTVCHQDLETLRSFADVEGTNLASLLLHCVQLTDGVSQIQSVKQIVPLLEKVDKNGVCDPATQSCLDILAGIYFSLALKNPLKKVLASSLNGLPEFFLTEATHSFTSHLQEELNTADLHSYRKVIDNISSCMENFNLGRSSVVNLLENVLQFLNKSLIEILEENRKFAGNHIVQTQLMNDLLVGIRVSMTLVQKVQGLQGDLCSEPGSPIWQTVCDLLSMFTRCLNDDDLLQTIQSTSGLAVILFVKTMFHPPEKLPGLISSLLLQSVDCTSIPEWFMNSCRSLCCADVSASTLLFLCQGTLAMLDWQDRSMGPSGEALLLDTVRVLFTLSSQIKESTLEMFLSRILASWTNSAIQILESSSPNLKASLNGDSSIARRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHQLTMGGADSVTDPFFLELTKSLLKLEWHIKGKYSCLGCLVESIGVEHILSIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKCQTVTNTWMDEWHETWVSPLLSILCGGNLDQKSYVIDYYLPRLLNYSPESLQYMVKILQASIDTETGSYNRRGALGALMACLRTARAHGHLQSATHAWEDLMCGTRIKQGLIHQHCQVRIDTLGLLCESNRSTEVVSIEEMQWVRFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSAPDSESGSSSERPPVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALSILGSVAEVFAVSEGNIQPVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMKLSSVTARQFQDAEKLQGLFQAALELSTSTKPYDCVTASYLLNLLIWQDALPASLTASQAQQLTHRAHGAAEKATVLERNTLVVIKCLMENLEDEISQAEDSLLQAASSFPMYGRVHCITRAFQKLPLNDLRLVSEWRPVVEGLLLLSYRLSAVVSPVIQSSSPEGLIPMDTDSESASRLQVILNEIQPRDTNAYFNQAKILKECDSFDLEDLSASVSNIDSSAEIKGKETKTCDVTAQMVLVCCWRSMKEVALLLGTLCQLLPMRPVPESSNGLLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSAVSLQKLPEQWLWNVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEPKKSKMDLLKITMKELISLALSVDGSKGTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSSLITRIFGVKRGKDELSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDTGKPDRHPSMFLLLLVLERLYPSPMDGTSSALSLAPFVPFIIRCGRSPIYRSREMAARALVPFITIDQIPSTLHALLDSLPNSTDQCFRQNHIHGTLLQVFHLLQAYVTDSRHRTNADFQHELSDITACTKAKLWLATRQNPCLVTRAVYIDILFLLTKCLDRPAESKQPALQSLGLQEDVRRIVLGSELVTGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQAIAIPLSFSRLLESSFPEVRLLTLDTLLERVMSSELEEKGPPPLLCSMGEDFLLLAMKENHPGCFCQVLKILYHMNPSEWLSQTEHCVHLSPKEFLIWTMDIASKDRSEIQSVALKLASKLIAHHVQTCEENKDSIAPELRQWVQLVVWSCGDHLPTASRLAAAEVLTSATPLFLTNPRPILELQDTLALWKCVLTLLQSEEQAVREAATEIVTVAMSQGNTCQSTAGGSHTGMEGSICDLQMRDPKARREFAFCQVNASVALALALAVLCDLLQQWDQLVPGLPILLGWLLGESDDPQYLMQSPHQGEDDYIFEKSEVNFWAETLTFVRYLCWQLFHLPCQSGQPYPHSQLCHLQTIASEKRHLVSELFRELPLSAEFLKTVEYTRLRIQEERSLAVLRLLAFLEGKEVLRAEDCPREWRQLMAPRTEASC", "length": 1964, "header": "tr|A0A9J7G3H0-1|A0A9J7G3H0_CRIGR Computationally mapped isoform of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Cricetulus griseus OX=10029 GN=Thada PE=3 SV=1 CANONICAL=A0A9J7G4P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3/entry#A0A9J7G4P3-1", "sequence": { "sequence": "MGVKKKREVQVAAVTVCHQDLETLRSFADVEGTNLASLLLHCVQLTDGVSQIQSVKQIVPLLEKVDKNGVCDPATQSCLDILAGIYFSLALKNPLKKVLASSLNGLPEFFLTEATHSFTSHLQEELNTADLHSYRKVIDNISSCMENFNLGRSSVVNLLENVLQFLNKSLIEILEENRKFAGNHIVQTQLMNDLLVGIRVSMTLVQKVQGLQGDLCSEPGSPIWQTVCDLLSMFTRCLNDDDLLQTIQSTSGLAVILFVKTMFHPPEKLPGLISSLLLQSVDCTSIPEWFMNSCRSLCCADVSASTLLFLCQGTLAMLDWQDRSMGPSGEALLLDTVRVLFTLSSHMFMELDNHHHSQPQSAPIFLDGHGGVVGRQRIKESTLEMFLSRILASWTNSAIQILESSSPNLKASLNGDSSIARRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHQLTMGGADSVTDPFFLELTKSLLKLEWHIKGKYSCLGCLVESIGVEHILSIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKCQTVTNTWMDEWHETWVSPLLSILCGGNLDQKSYVIDYYLPRLLNYSPESLQYMVKILQASIDTETGSYNRRGALGALMACLRTARAHGHLQSATHAWEDLMCGTRIKQGLIHQHCQVRIDTLGLLCESNRSTEVVSIEEMQWVRFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSAPDSESGSSSERPPVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALSILGSVAEVFAVSEGNIQPVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMKLSSVTARQFQDAEKLQGLFQAALELSTSTKPYDCVTASYLLNLLIWQDALPASLTASQAQQLTHRAHGAAEKATVLERNTLVVIKCLMENLEDEISQAEDSLLQAASSFPMYGRVHCITRAFQKLPLNDLRLVSEWRPVVEGLLLLSYRLSAVVSPVIQSSSPEGLIPMDTDSESASRLQVILNEIQPRDTNAYFNQAKILKECDSFDLEDLSASVSNIDSSAEIKGKETKTCDVTAQMVLVCCWRSMKEVALLLGTLCQLLPMRPVPESSNGLLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSAVSLQKLPEQWLWNVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEPKKSKMDLLKITMKELISLALSVDGSKGTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSSLITRIFGVKRGKDELSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDTGKPDRHPSMFLLLLVLERLYPSPMDGTSSALSLAPFVPFIIRCGRSPIYRSREMAARALVPFITIDQIPSTLHALLDSLPNSTDQCFRQNHIHGTLLQVFHLLQAYVTDSRHRTNADFQHELSDITACTKAKLWLATRQNPCLVTRAVYIDILFLLTKCLDRPAESKQPALQSLGLQEDVRRIVLGSELVTGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQAIAIPLSFSRLLESSFPEVRLLTLDTLLERVMSSELEEKGPPPLLCSMGEDFLLLAMKENHPGCFCQVLKILYHMNPSEWLSQTEHCVHLSPKEFLIWTMDIASKDRSEIQSVALKLASKLIAHHVQTCEENKDSIAPELRQWVQLVVWSCGDHLPTASRLAAAEVLTSATPLFLTNPRPILELQDTLALWKCVLTLLQSEEQAVREAATEIVTVAMSQGNTCQSTAGGSHTGMEGSICDLQMRDPKARREFAFCQVNASVALALALAVLCDLLQQWDQLVPGLPILLGWLLGESDDPQYLMQSPHQGEDDYIFEKSEVNFWAETLTFVRYLCWQLFHLPCQSGQPYPHSQLCHLQTIASEKRHLVSELFRELPLSAEFLKTVEYTRLRIQEERSLAVLRLLAFLEGKEVLRAEDCPREWRQLMAPRTEASC", "length": 1995, "header": "tr|A0A9J7G4P3-1|A0A9J7G4P3_CRIGR Isoform 1 of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Cricetulus griseus OX=10029 GN=Thada PE=3 SV=1 CANONICAL=A0A9J7G4P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JST9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3/entry#A0A9J7JST9-1", "sequence": { "sequence": "MGVKKKREVQVAAVTVCHQDLETLRSFADVEGTNLASLLLHCVQLTDGVSQIQSVKQIVPLLEKVDKNGVCDPATQSCLDILAGIYFSLALKNPLKKVLASSLNGLPEFFLTEATHSFTSHLQEELNTADLHSYRKVIDNISSCMENFNLGRSSVVNLLENVLQFLNKSLIEILEENRKFAGNHIVQTQLMNDLLVGIRVSMTLVQKVQGLQGDLCSEPGSPIWQTVCDLLSMFTRCLNDDDLLQTIQSTSGLAVILFVKTMFHPPEKLPGLISSLLLQSVDCTSIPEWFMNSCRSLCCADVSASTLLFLCQGTLAMLDWQDRSMGPSGEALLLDTVRVLFTLSSHMFMELDNHHHSQPQSAPIFLDGHGGVVGRQRIKESTLEMFLSRILASWTNSAIQILESSSPNLKASLNGDSSIARRLLEYVYTHWEHPLDALRHQTKIIFRNLLQMHQLTMGGADSVTDPFFLELTKSLLKLEWHIKGKYSCLGCLVESIGVEHILSIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKCQTVTNTWMDEWHETWVSPLLSILCGGNLDQKSYVIDYYLPRLLNYSPESLQYMVKILQASIDTETGSYNRRGALGALMACLRTARAHGHLQSATHAWEDLMCGTRIKQGLIHQHCQVRIDTLGLLCESNRSTEVVSIEEMQWVRFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSAPDSESGSSSERPPVSLQQYKNFMSSVCNILFEALFPGSSYSTRFSALSILGSVAEVFAVSEGNIQPVYQLSHDIDAGRFQILMECFTSTFEEVKTLAFDLLMKLSSVTARQFQDAEKLQGLFQAALELSTSTKPYDCVTASYLLNLLIWQDALPASLTASQAQQLTHRAHGAAEKATVLERNTLVVIKCLMENLEDEISQAEDSLLQAASSFPMYGRVHCITRAFQKLPLNDLRLVSEWRPVVEGLLLLSYRLSAVVSPVIQSSSPEGLIPMDTDSESASRLQVILNEIQPRDTNAYFNQAKILKECDSFDLEDLSASVSNIDSSAEIKGKETKTCDVTAQMVLVCCWRSMKEVALLLGTLCQLLPMRPVPESSNGLLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSAVSLQKLPEQWLWNVLEEIKSSDPSSKLCATRRSAGIPFYIQALLASEPKKSKMDLLKITMKELISLALSVDGSKGTVPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSSLITRIFGVKRGKDELSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDTGKPDRHPSMFLLLLVLERLYPSPMDGTSSALSLAPFVPFIIRCGRSPIYRSREMAARALVPFITIDQIPSTLHALLDSLPNSTDQCFRQNHIHGTLLQVFHLLQAYVTDSRHRTNADFQHELSDITACTKAKLWLATRQNPCLVTRAVYIDILFLLTKCLDRPAESKQPALQSLGLQEDVRRIVLGSELVTGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAEGQAIAIPLSFSRLLESSFPEVRLLTLDTLLERVMSSELEEKGPPPLLCSMGEDFLLLAMKENHPGCFCQVLKILYHMNPSEWLSQTEHCVHLSPKEFLIWTMDIASKDRSEIQSVALKLASKLIAHHVQTCEENKDSIAPELRQWVQLVVWSCGDHLPTASRLAAAEVLTSATPLFLTNPRPILELQDTLALWKCVLTLLQSEEQAVREAATEIVTVAMSQGNTCQSTEFAFCQVNASVALALALAVLCDLLQQWDQLVPGLPILLGWLLGESDDPQYLMQSPHQGEDDYIFEKSEVNFWAETLTFVRYLCWQLFHLPCQSGQPYPHSQLCHLQTIASEKRHLVSELFRELPLSAEFLKTVEYTRLRIQEERSLAVLRLLAFLEGKEVLRAEDCPREWRQLMAPRTEASC", "length": 1971, "header": "tr|A0A9J7JST9-1|A0A9J7JST9_CRIGR Computationally mapped isoform of tRNA (32-2'-O)-methyltransferase regulator THADA OS=Cricetulus griseus OX=10029 GN=Thada PE=3 SV=1 CANONICAL=A0A9J7G4P3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G1K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1K4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759859", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759859", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3" } ], "pmid": "" }, { "name": "tRNA nucleoside ribose methylation", "id": "GO:0002128", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002128", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3" } ], "pmid": "" }, { "name": "negative regulation of endoplasmic reticulum calcium ion concentration", "id": "GO:0032471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032471", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1276, "end_pos": 1278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1417, "end_pos": 1419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1821, "end_pos": 1823, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 671, "end_pos": 673, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G4P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3" }, { "id": "PF10350", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10350" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF2428", "eco_id": "ECO_0000259", "start_pos": 973, "end_pos": 1273, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G4P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3" }, { "id": "PF25151", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "tRNA (32-2'-O)-methyltransferase regulator THADA-like C-terminal TPR repeats region", "eco_id": "ECO_0000259", "start_pos": 1275, "end_pos": 1438, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G4P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4P3" }, { "id": "PF25150", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25150" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "tRNA (32-2'-O)-methyltransferase regulator THADA-like TPR repeats region", "eco_id": "ECO_0000259", "start_pos": 553, "end_pos": 825, "start_aa": "Trp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1276, "end_pos": 1278 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 1417, "end_pos": 1419 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 1821, "end_pos": 1823 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 671, "end_pos": 673 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G468-1", "uniprot_ac": "A0A9J7G468", "uniprot_id": "A0A9J7G468_CRIGR", "mass": { "chemical_mass": 58247.0, "monoisotopic_mass": 58247.0 }, "refseq": { "ac": "XP_007643844", "name": "DDB1- and CUL4-associated factor 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643844" }, "gene_names": [ { "name": "Dcaf4", "type": "recommended", "evidence": [ { "id": "A0A9J7G468", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468" } ] }, { "name": "Dcaf4", "type": "synonym", "evidence": [ { "id": "XP_007643844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643844" } ] } ], "protein_names": [ { "name": "DDB1- and CUL4-associated factor 4", "type": "recommended", "evidence": [ { "id": "A0A9J7G468", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468/entry#names_and_taxonomy" } ] }, { "name": "DDB1- and CUL4-associated factor 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007643844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643844" } ] }, { "name": "WD repeat-containing protein 21A", "type": "synonym", "evidence": [ { "id": "A0A9J7G468", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614123.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007643844", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643844" } ] }, { "annotation": "May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G237", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G237#function" }, { "database": "UniProtKB", "id": "ARBA00002614", "url": "https://www.uniprot.org/uniprotkb/ARBA00002614#function" }, { "database": "UniProtKB", "id": "A0A9J7G288", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G288#function" }, { "database": "UniProtKB", "id": "A0A9J7G468", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468#function" }, { "database": "UniProtKB", "id": "A0A9J7JPS0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPS0#function" }, { "database": "UniProtKB", "id": "A0A9J7K5U0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5U0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G468", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dcaf4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468", "locus": {} } ], "crossref": [ { "id": "A0A9J7G468", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G468", "database": "AlphaFoldDB", "categories": [] }, { "id": "100752324", "url": "https://www.ncbi.nlm.nih.gov/gene/100752324", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752324", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752324", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G237", "url": "https://www.orthodb.org/?gene=A0A9J7G237", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G288", "url": "https://www.orthodb.org/?gene=A0A9J7G288", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G468", "url": "https://www.orthodb.org/?gene=A0A9J7G468", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44472", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44472", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44472:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44472:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23761", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23761", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007643844", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643844", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G237", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G237", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G237-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G237-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G288", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G288", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G288-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G288-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G468", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G468-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPS0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5U0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5U0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSALLGAEGTEMSRSIWQSRRRRGRGRQQNPAFRQSDSSERYTTATSKSPQDSGHHDAEAPSTSSGTAGESSVPELPGFYFDPEKNRYFRLLPGHNNCNPLTKEGIRHKEMESRRLQLLQQEDRQKKKITRMGFNASSILRKKQLGFLNITNYCRLAHELRVSCMERRKVEIQSSDPSALASDQFNFILADTSSDRLFTVNDVQIGGSKYGIINLQGLKAPTFKVHMYENLYFTNRKVNSVCWASLNHLDSHILLCLMGLAETPGCATLLPASLFVSNHQAGTDQPGVLCSFRIPGAWSCAWSLNTQANNCFSTGLSRRVLLTNVVTGHRQSYGTNSDVLAQQFAVKTPLLFNGCRSGEIFAIDLRSPSQAKGWKATHIFHDSAVTSVRVLKEEQYVMASDMAGKIKLWDLRATKCVRQYEGHVNEYAYLPLHVHEEEGILVAVGQDCYTRIWSLHDAHLLRTIPSPYPTSKANIPSVAFSPRLGGPQGAPGLLMAVQQDLYCFSYSSFCPGNLEEDRWE", "length": 521, "header": "tr|A0A9J7G468-1|A0A9J7G468_CRIGR Isoform 1 of DDB1- and CUL4-associated factor 4 OS=Cricetulus griseus OX=10029 GN=Dcaf4 PE=4 SV=1 CANONICAL=A0A9J7G468-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G237-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468/entry#A0A9J7G237-1", "sequence": { "sequence": "MSRSIWQSRRRRGRGRQQNPAFRQSDSSERYTTATSKSPQDSGHHDAEAPSTSSGTAGESSVPELPGFYFDPEKNRYFRLLPGHNNCNPLTKEGIRHKEMESRRLQLLQQEDRQKKKITRMGFNASSILRKKQLGFLNITNYCRLAHELRVSCMERRKVEIQSSDPSALASDQFNFILADTSSDRLFTVNDVQIGGSKYGIINLQGLKAPTFKVHMYENLYFTNRKVNSVCWASLNHLDSHILLCLMGLAETPGCATLLPASLFVSNHQAGTDQPGVLCSFRIPGAWSCAWSLNTQANNCFSTGLSRRVLLTNVVTGHRQSYGTNSDVLAQQFAVKTPLLFNGCRSGEIFAIDLRSPSQAKGWKATHIFHDSAVTSVRVLKEEQYVMASDMAGKIKLWDLRATKCVRQYEGHVNEYAYLPLHVHEEEGILVAVGQDCYTRIWSLHDAHLLRTIPSPYPTSKANIPSVAFSPRLGGPQGAPGLLMAVQQDLYCFSYSSFCPGNLEEDRWE", "length": 509, "header": "tr|A0A9J7G237-1|A0A9J7G468_CRIGR Computationally mapped isoform of DDB1- and CUL4-associated factor 4 OS=Cricetulus griseus OX=10029 GN=Dcaf4 PE=4 SV=1 CANONICAL=A0A9J7G468-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G288-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468/entry#A0A9J7G288-1", "sequence": { "sequence": "MPSALLGAEGTEMSRSIWQSRRRRGRGRQQNPAFRQSDSSERYTTATSKSPQDSGHHDAEAPSTSSGTAGESSVPELPGFYFDPEKNRYFRLLPGHNNCNPLTKEGIRHKEMESRRLQLLQQEDRQKKKITRMGFNASSILRKKQLGFLNITNYCRLAHELRVSCMERRKVEIQSSDPSALASDQFNFILADTSSDRLFTVNDVQIGGSKYGIINLQGLKAPTFKVHMYENLYFTNRKVNSVCWASLNHLDSHILLCLMGLAETPGCATLLPASLFVSNHQGTDQPGVLCSFRIPGAWSCAWSLNTQANNCFSTGLSRRVLLTNVVTGHRQSYGTNSDVLAQQFAVKTPLLFNGCRSGEIFAIDLRSPSQAKGWKATHIFHDSAVTSVRVLKEEQYVMASDMAGKIKLWDLRATKCVRQYEGHVNEYAYLPLHVHEEEGILVAVGQDCYTRIWSLHDAHLLRTIPSPYPTSKANIPSVAFSPRLGGPQGAPGLLMAVQQDLYCFSYSSFCPGNLEEDRWE", "length": 520, "header": "tr|A0A9J7G288-1|A0A9J7G468_CRIGR Computationally mapped isoform of DDB1- and CUL4-associated factor 4 OS=Cricetulus griseus OX=10029 GN=Dcaf4 PE=4 SV=1 CANONICAL=A0A9J7G468-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G468-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468/entry#A0A9J7G468-1", "sequence": { "sequence": "MPSALLGAEGTEMSRSIWQSRRRRGRGRQQNPAFRQSDSSERYTTATSKSPQDSGHHDAEAPSTSSGTAGESSVPELPGFYFDPEKNRYFRLLPGHNNCNPLTKEGIRHKEMESRRLQLLQQEDRQKKKITRMGFNASSILRKKQLGFLNITNYCRLAHELRVSCMERRKVEIQSSDPSALASDQFNFILADTSSDRLFTVNDVQIGGSKYGIINLQGLKAPTFKVHMYENLYFTNRKVNSVCWASLNHLDSHILLCLMGLAETPGCATLLPASLFVSNHQAGTDQPGVLCSFRIPGAWSCAWSLNTQANNCFSTGLSRRVLLTNVVTGHRQSYGTNSDVLAQQFAVKTPLLFNGCRSGEIFAIDLRSPSQAKGWKATHIFHDSAVTSVRVLKEEQYVMASDMAGKIKLWDLRATKCVRQYEGHVNEYAYLPLHVHEEEGILVAVGQDCYTRIWSLHDAHLLRTIPSPYPTSKANIPSVAFSPRLGGPQGAPGLLMAVQQDLYCFSYSSFCPGNLEEDRWE", "length": 521, "header": "tr|A0A9J7G468-1|A0A9J7G468_CRIGR Isoform 1 of DDB1- and CUL4-associated factor 4 OS=Cricetulus griseus OX=10029 GN=Dcaf4 PE=4 SV=1 CANONICAL=A0A9J7G468-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468/entry#A0A9J7JPS0-1", "sequence": { "sequence": "MYENLYFTNRKVNSVCWASLNHLDSHILLCLMGLAETPGCATLLPASLFVSNHQAGTDQPGVLCSFRIPGAWSCAWSLNTQANNCFSTGLSRRVLLTNVVTGHRQSYGTNSDVLAQQFAVKTPLLFNGCRSGEIFAIDLRSPSQAKGWKATHIFHDSAVTSVRVLKEEQYVMASDMAGKIKLWDLRATKCVRQYEGHVNEYAYLPLHVHEEEGILVAVGQDCYTRIWSLHDAHLLRTIPSPYPTSKANIPSVAFSPRLGGPQGAPGLLMAVQQDLYCFSYSSFCPGNLEEDRWE", "length": 294, "header": "tr|A0A9J7JPS0-1|A0A9J7JPS0_CRIGR Computationally mapped isoform of DDB1- and CUL4-associated factor 4 OS=Cricetulus griseus OX=10029 GN=Dcaf4 PE=4 SV=1 CANONICAL=A0A9J7G468-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468/entry#A0A9J7K5U0-1", "sequence": { "sequence": "MESRRLQLLQQEDRQKKKITRMGFNASSILRKKQLGFLNITNYCRLAHELRVSCMERRKVEIQSSDPSALASDQFNFILADTSSDRLFTVNDVQIGGSKYGIINLQGLKAPTFKVHMYENLYFTNRKVNSVCWASLNHLDSHILLCLMGLAETPGCATLLPASLFVSNHQAGTDQPGVLCSFRIPGAWSCAWSLNTQANNCFSTGLSRRVLLTNVVTGHRQSYGTNSDVLAQQFAVKTPLLFNGCRSGEIFAIDLRSPSQAKGWKATHIFHDSAVTSVRVLKEEQYVMASDMAGKIKLWDLRATKCVRQYEGHVNEYAYLPLHVHEEEGILVAVGQDCYTRIWSLHDAHLLRTIPSPYPTSKANIPSVAFSPRLGGPQGAPGLLMAVQQDLYCFSYSSFCPGNLEEDRWE", "length": 410, "header": "tr|A0A9J7K5U0-1|A0A9J7K5U0_CRIGR Computationally mapped isoform of DDB1- and CUL4-associated factor 4 OS=Cricetulus griseus OX=10029 GN=Dcaf4 PE=4 SV=1 CANONICAL=A0A9J7G468-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G237", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G237" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G237", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G237" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752324", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752324", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Cul4-RING E3 ubiquitin ligase complex", "id": "GO:0080008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080008", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G468", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G468" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 150, "end_pos": 152 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G769-1", "uniprot_ac": "A0A9J7G769", "uniprot_id": "A0A9J7G769_CRIGR", "mass": { "chemical_mass": 46749.0, "monoisotopic_mass": 46749.0 }, "refseq": { "ac": "XP_027275514", "name": "sorting nexin-6 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275514" }, "gene_names": [ { "name": "Snx6", "type": "recommended", "evidence": [ { "id": "A0A9J7G769", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G769" } ] }, { "name": "Snx6", "type": "synonym", "evidence": [ { "id": "XP_027275514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275514" } ] } ], "protein_names": [ { "name": "Sorting nexin", "type": "recommended", "evidence": [ { "id": "A0A9J7G769", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G769/entry#names_and_taxonomy" } ] }, { "name": "sorting nexin-6 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027275514", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275514" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275514", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275514" } ] }, { "annotation": "Involved in several stages of intracellular trafficking.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V5#function" }, { "database": "UniProtKB", "id": "PIRNR036924", "url": "https://www.uniprot.org/uniprotkb/PIRNR036924#function" }, { "database": "UniProtKB", "id": "A0A9J7G769", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G769#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G769", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G769" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Snx6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G769", "locus": {} } ], "crossref": [ { "id": "A0A9J7G769", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G769", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07292", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07292", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07662", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07662", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757927", "url": "https://www.ncbi.nlm.nih.gov/gene/100757927", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014637", "database": "InterPro", 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"categories": [ "Protein" ] }, { "id": "A0A9J7G2V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G769", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G769", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G769-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G769-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMQEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRKDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT", "length": 407, "header": "tr|A0A9J7G769-1|A0A9J7G769_CRIGR Isoform 1 of Sorting nexin OS=Cricetulus griseus OX=10029 GN=Snx6 PE=3 SV=1 CANONICAL=A0A9J7G769-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G2V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G769/entry#A0A9J7G2V5-1", "sequence": { "sequence": "MMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRKDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT", "length": 406, "header": "tr|A0A9J7G2V5-1|A0A9J7G769_CRIGR Computationally mapped isoform of Sorting nexin OS=Cricetulus griseus OX=10029 GN=Snx6 PE=3 SV=1 CANONICAL=A0A9J7G769-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G769-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G769/entry#A0A9J7G769-1", "sequence": { "sequence": "MMQEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRKDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGDT", "length": 407, "header": "tr|A0A9J7G769-1|A0A9J7G769_CRIGR Isoform 1 of Sorting nexin OS=Cricetulus griseus OX=10029 GN=Snx6 PE=3 SV=1 CANONICAL=A0A9J7G769-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G2V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2V5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757927", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757927", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G769", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G769" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G769", "url": 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} ] } ], "protein_names": [ { "name": "Tight junction protein ZO-3 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7G7P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3/entry#names_and_taxonomy" } ] }, { "name": "tight junction protein ZO-3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027275046", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275046" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275046" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tjp3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3", "locus": {} } ], "crossref": [ { "id": "A0A9J7G7P3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G7P3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06727", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06727", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772461", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G7P3", "url": "https://www.orthodb.org/?gene=A0A9J7G7P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13865", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13865", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13865:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13865:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275046", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275046", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G383", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G383", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G383-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G383-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3A9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQB3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVRFQVAHMEELTIWEQHTATLCKDPRRGFGIAVSGGHNRGGSGSVLVSDVIPGGPAEGRLQTGDHIVMVNGVSVENVTSAFAIQILKTCTKTANITVKRPRRIQLPATKASASPDPEEADHGRGYEGDSSSGSGRSWGERSRRTRTGRRSRLGSQGRWSSGGGSEPNGLDLVSGYKRLPKQDMLMRPHKSVLVKRRNSEEFGVKLGSQIFIKHITDSGLAARNRGLQEGDLILQINGVSSANLSLSDTRQLIEKSEGELTLLVLRDSGQFLVNIPPAVSDSDSSLMEDISDLTSELSQALPSHIPPPPLQGQRSPEASPMDSPVESPRPRTRELSMDSRAIAEPECPGESGYDIYRVPSRQSLEDRGYSPDTRVVRFPKGASIGLRLAGGNDVGIFVSGVQAGSPADGQGIQEGDEILQVNGMPFRNLTREEAVQFLLELPPGEDVELVTQSKQDIFRKMVQSRVGDSFYIRTHFELEPSPPYGLGFTRGDVFHVVDTLYPGSGLGHGGRGGLWLAARMGRDLQEQERGVIPNQSRAEQLASLEAVQRAAGVGPGASSASNPRAEFWRLRGLRRGAKKTTQRSREDLSALTRQGHYPPYERVVLREASFKRPVVILGPVADIAMKRLTAEMPDQFEIAESVSRADNPNKIIKLDTVRVIAERDKHALLDVTPSAIERLNYVQYYPIVVFCAPESRPALKALREWLAPASRRSSRRLYAQAQKLQKHSGHLFTAIVPLHGTGDSWYREVKAVVQQQQARPIWTAEDQLEGSSEDLDLPGRSLDASSGDLSCDSRANSDYEDTDGVYTDGEGSGPQDADEEPRLPALARSSEPAWEGIAAEWDMRADSRHPQGQDSMRPAPTSAPRTYEHDALRKKFTRARDVESSDDDGYDWGPATDL", "length": 899, "header": "tr|A0A9J7G7P3-1|A0A9J7G7P3_CRIGR Isoform 1 of Tight junction protein ZO-3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tjp3 PE=3 SV=1 CANONICAL=A0A9J7G7P3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G383-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3/entry#A0A9J7G383-1", "sequence": { "sequence": "MAVRFQVAHMEELTIWEQHTATLCKDPRRGFGIAVSGGHNRGGSGSVLVSDVIPGGPAEGRLQTGDHIVMVNGVSVENVTSAFAIQILKTCTKTANITVKRPRRIQLPATKASASPDPEEADHGRGYEGDSSSGSGRSWGERSRRTRTGRRSRLGSQGRWSSGGGSEPNGLDLVSGYKRLPKQDMLMRPHKSVLVKRRNSEEFGVKLGSQIFIKHITDSGLAARNRGLQEGDLILQINGVSSANLSLSDTRQLIEKSEGELTLLVLRDSGQFLVNIPPAVSDSDSSLMEDISDLTSELSQALPSHIPPPPLQGQRSPEASPMDSPVESPRPRTRELSMDSRAIAEPECPGESGYDIYRVPSRQSLEDRGPDTRVVRFPKGASIGLRLAGGNDVGIFVSGVQAGSPADGQGIQEGDEILQVNGMPFRNLTREEAVQFLLELPPGEDVELVTQSKQDIFRKMVQSRVGDSFYIRTHFELEPSPPYGLGFTRGDVFHVVDTLYPGSGLGHGGRGGLWLAARMGRDLQEQERGVIPNQSRAEQLASLEAVQRAAGVGPGASSASNPRAEFWRLRGLRRGAKKTTQRSREDLSALTRQGHYPPYERVVLREASFKRPVVILGPVADIAMKRLTAEMPDQFEIAESVSRADNPNKIIKLDTVRVIAERDKHALLDVTPSAIERLNYVQYYPIVVFCAPESRPALKALREWLAPASRRSSRRLYAQAQKLQKHSGHLFTAIVPLHGTGDSWYREVKAVVQQQQARPIWTAEDQLEGSSEDLDLPGRSLDASSGDLSCDSRANSDYEDTDGVYTDGEGSGPQDADEEPRLPALARSSEPAWEGIAAEWDMRADSRHPQGQDSMRPAPTSAPRTYEHDALRKKFTRARDVESSDDDGYDWGPATDL", "length": 897, "header": "tr|A0A9J7G383-1|A0A9J7G7P3_CRIGR Computationally mapped isoform of Tight junction protein ZO-3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tjp3 PE=3 SV=1 CANONICAL=A0A9J7G7P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3/entry#A0A9J7G3A9-1", "sequence": { "sequence": "MAVRFQVAHMEELTIWEQHTATLCKDPRRGFGIAVSGGHNRGGSGSVLVSDVIPGGPAEGRLQTGDHIVMVNGVSVENVTSAFAIQILKTCTKTANITVKRPRRIQLPATKASASPDPEEADHGRGYEGDSSSGSGRSWGERSRRTRTGRRSRLGSQGRWSSGGGSEPNGLDLVSGYKRLPKQDMLMRPHKSVLVKRRNSEEFGVKLGSQIFIKHITDSGLAARNRGLQEGDLILQINGVSSANLSLSDTRQLIEKSEGELTLLVLRDSGQFLVNIPPAVSDSDSSLMEDISDLTSELSQALPSHIPPPPLQGQRSPEASPMDSPVESPRPRTRELSMDSRAIAEPECPGESGYDIYRVPSRQSLEDRGYSPDTRVVRFPKGASIGLRLAGGNDVGIFVSGVQAGSPADGQGIQEGDEILQVNGMPFRNLTREEAVQFLLELPPGEDVELVTQSKQDIFRKMVQSRVGDSFYIRTHFELEPSPPYGLGFTRGDVFHVVDTLYPGSGLGHGGRGGLWLAARMGRDLQEQERGVIPNQSRAEQLASLEAVQRAAGVGPGASSASNPRAEFWRLRGLRRGAKKTTQRSREDLSALTRQGHYPPYERVVLREASFKRPVVILGPVADIAMKRLTAEMPDQFEIAESVSRADNPNKIIKLDTVRVIAERDKHALLDVTPSAIERLNYVQYYPIVVFCAPESRPALKALREWLAPASRRSSRRLYAQAQKLQKHSGHLFTAIVPLHGTGDSWYREVKAVVQQQQARPIWTAEDQLEGSSEDLDLPGRSLDASSGDLSCDSRANSDYEDTDGVYTDGEGSGPQDADEEPRLPALARSSEPAWEGIAAEWDMRADSRHPQGQDSMRTYEHDALRKKFTRARDVESSDDDGYDWGPATDL", "length": 891, "header": "tr|A0A9J7G3A9-1|A0A9J7G7P3_CRIGR Computationally mapped isoform of Tight junction protein ZO-3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tjp3 PE=3 SV=1 CANONICAL=A0A9J7G7P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3/entry#A0A9J7G7P3-1", "sequence": { "sequence": "MAVRFQVAHMEELTIWEQHTATLCKDPRRGFGIAVSGGHNRGGSGSVLVSDVIPGGPAEGRLQTGDHIVMVNGVSVENVTSAFAIQILKTCTKTANITVKRPRRIQLPATKASASPDPEEADHGRGYEGDSSSGSGRSWGERSRRTRTGRRSRLGSQGRWSSGGGSEPNGLDLVSGYKRLPKQDMLMRPHKSVLVKRRNSEEFGVKLGSQIFIKHITDSGLAARNRGLQEGDLILQINGVSSANLSLSDTRQLIEKSEGELTLLVLRDSGQFLVNIPPAVSDSDSSLMEDISDLTSELSQALPSHIPPPPLQGQRSPEASPMDSPVESPRPRTRELSMDSRAIAEPECPGESGYDIYRVPSRQSLEDRGYSPDTRVVRFPKGASIGLRLAGGNDVGIFVSGVQAGSPADGQGIQEGDEILQVNGMPFRNLTREEAVQFLLELPPGEDVELVTQSKQDIFRKMVQSRVGDSFYIRTHFELEPSPPYGLGFTRGDVFHVVDTLYPGSGLGHGGRGGLWLAARMGRDLQEQERGVIPNQSRAEQLASLEAVQRAAGVGPGASSASNPRAEFWRLRGLRRGAKKTTQRSREDLSALTRQGHYPPYERVVLREASFKRPVVILGPVADIAMKRLTAEMPDQFEIAESVSRADNPNKIIKLDTVRVIAERDKHALLDVTPSAIERLNYVQYYPIVVFCAPESRPALKALREWLAPASRRSSRRLYAQAQKLQKHSGHLFTAIVPLHGTGDSWYREVKAVVQQQQARPIWTAEDQLEGSSEDLDLPGRSLDASSGDLSCDSRANSDYEDTDGVYTDGEGSGPQDADEEPRLPALARSSEPAWEGIAAEWDMRADSRHPQGQDSMRPAPTSAPRTYEHDALRKKFTRARDVESSDDDGYDWGPATDL", "length": 899, "header": "tr|A0A9J7G7P3-1|A0A9J7G7P3_CRIGR Isoform 1 of Tight junction protein ZO-3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tjp3 PE=3 SV=1 CANONICAL=A0A9J7G7P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3/entry#A0A9J7JQB3-1", "sequence": { "sequence": "MAVAHMEELTIWEQHTATLCKDPRRGFGIAVSGGHNRGGSGSVLVSDVIPGGPAEGRLQTGDHIVMVNGVSVENVTSAFAIQILKTCTKTANITVKRPRRIQLPATKASASPDPEEADHGRGYEGDSSSGSGRSWGERSRRTRTGRRSRLGSQGRWSSGGGSEPNGLDLVSGYKRLPKQDMLMRPHKSVLVKRRNSEEFGVKLGSQIFIKHITDSGLAARNRGLQEGDLILQINGVSSANLSLSDTRQLIEKSEGELTLLVLRDSGQFLVNIPPAVSDSDSSLMEDISDLTSELSQALPSHIPPPPLQGQRSPEASPMDSPVESPRPRTRELSMDSRAIAEPECPGESGYDIYRVPSRQSLEDRGYSPDTRVVRFPKGASIGLRLAGGNDVGIFVSGVQAGSPADGQGIQEGDEILQVNGMPFRNLTREEAVQFLLELPPGEDVELVTQSKQDIFRKMVQSRVGDSFYIRTHFELEPSPPYGLGFTRGDVFHVVDTLYPGSGLGHGGRGGLWLAARMGRDLQEQERGVIPNQSRAEQLASLEAVQRAAGVGPGASSASNPRAEFWRLRGLRRGAKKTTQRSREDLSALTRQGHYPPYERVVLREASFKRPVVILGPVADIAMKRLTAEMPDQFEIAESVSRADNPNKIIKLDTVRVIAERDKHALLDVTPSAIERLNYVQYYPIVVFCAPESRPALKALREWLAPASRRSSRRLYAQAQKLQKHSGHLFTAIVPLHGTGDSWYREVKAVVQQQQARPIWTAEDQLEGSSEDLDLPGRSLDASSGDLSCDSRANSDYEDTDGVYTDGEGSGPQDADEEPRLPALARSSEPAWEGIAAEWDMRADSRHPQGQDSMRPAPTSAPRTYEHDALRKKFTRARDVESSDDDGYDWGPATDL", "length": 895, "header": "tr|A0A9J7JQB3-1|A0A9J7JQB3_CRIGR Computationally mapped isoform of Tight junction protein ZO-3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Tjp3 PE=3 SV=1 CANONICAL=A0A9J7G7P3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G383", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G383" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G383", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G383" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772461", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein localization to cell-cell junction", "id": "GO:0150105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0150105", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" } ], "pmid": "" }, { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" } ], "pmid": "" }, { "name": "establishment of endothelial intestinal barrier", "id": "GO:0090557", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090557", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" } ], "pmid": "" }, { "name": "cell-cell junction organization", "id": "GO:0045216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045216", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" } ], "pmid": "" }, { "name": "positive regulation of blood-brain barrier permeability", "id": "GO:1905605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905605", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G7P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 655, "end_pos": 755, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G7P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7P3" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 103, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 244, "end_pos": 246 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 78, "end_pos": 80 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3H2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767851", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767851", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3H2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": 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"monoisotopic_mass": 95533.0 }, "refseq": { "ac": "XP_027275228", "name": "mediator of RNA polymerase II transcription subunit 16 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275228" }, "gene_names": [ { "name": "Med16", "type": "recommended", "evidence": [ { "id": "A0A9J7G3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8" } ] }, { "name": "MED16", "type": "synonym", "evidence": [ { "id": "A0A9J7G3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8" } ] }, { "name": "Med16", "type": "synonym", "evidence": [ { "id": "XP_027275228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275228" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 16", "type": "recommended", "evidence": [ { "id": "A0A9J7G3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8/entry#names_and_taxonomy" } ] }, { "name": "Mediator complex subunit 16", "type": "synonym", "evidence": [ { "id": "A0A9J7G3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8/entry#names_and_taxonomy" } ] }, { "name": "mediator of RNA polymerase II transcription subunit 16 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027275228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275228" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275228" } ] }, { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3H8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8#function" }, { "database": "UniProtKB", "id": "RU364149", "url": "https://www.uniprot.org/uniprotkb/RU364149#function" }, { "database": "UniProtKB", "id": "ARBA00025687", "url": "https://www.uniprot.org/uniprotkb/ARBA00025687#function" }, { "database": "UniProtKB", "id": "A0A9J7G3J9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J9#function" }, { "database": "UniProtKB", "id": "A0A9J7JQF9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQF9#function" }, { "database": "UniProtKB", "id": "A0A9J7GZH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZH3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3H8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Med16", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8", "locus": {} } ], "crossref": [ { "id": "A0A9J7G3H8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G3H8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100763586", "url": "https://www.ncbi.nlm.nih.gov/gene/100763586", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021665", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021665", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048616", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048616", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763586", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763586", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G3H8", "url": "https://www.orthodb.org/?gene=A0A9J7G3H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13224:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13224:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11635", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11635", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275228", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G3H8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3J9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3J9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQF9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPDPGRWGECGSRQPGRLGARSGQEPGTVLGAVGIMELVYVCEWENWAKNTYCPSLPLACAWSCRNLIAFTTDLRNDDQDLTHMIHILDTEHPWEVHSVNSGHSEAITCLEWDQSGSRLLSADADGHIKCWSMADHLANSWESSVGSQVEGDSIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVAAADGSSASPVKFYKVCVSVVSEKCRIDTEILPSLFMRCTTDPNRKDRFPAITHLKFLARDMSEQVLLCASSQTSSLVECWSLRKEGLPVNNIFQQISPVVGDKQPMILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASETQFYPGLGLVLAFQDGSVQMVHRLSLQTMAAFYSSTPRSLDEPTLKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGKLSMLRISPSLGHPLEPKLALQHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVERLHEEYTRQKPALQQVLSTRILAMKASLCKLSPCTVARVCDYHTKLFLMAITSTLKSLLRPHFLNTPDKSPGDRLAEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLVSLPNQGSPLRPGHSFLRDGTSLGTLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPASEPDEGLVDECCLLPSQLLVPSLDWLPASDGLVSRLQPKQPLRLRFGRAPTLPSNTSTLQLDGLARAPGQPKIDHLRRLHLGAYPTEECKACTRCGCVTMLKSPNKATAVKQWEQRWIKNCLCGGLWRRVPLSCP", "length": 865, "header": "tr|A0A9J7G3H8-1|A0A9J7G3H8_CRIGR Isoform 1 of Mediator of RNA polymerase II transcription subunit 16 OS=Cricetulus griseus OX=10029 GN=Med16 PE=3 SV=1 CANONICAL=A0A9J7G3H8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G3H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8/entry#A0A9J7G3H8-1", "sequence": { "sequence": "MAAPDPGRWGECGSRQPGRLGARSGQEPGTVLGAVGIMELVYVCEWENWAKNTYCPSLPLACAWSCRNLIAFTTDLRNDDQDLTHMIHILDTEHPWEVHSVNSGHSEAITCLEWDQSGSRLLSADADGHIKCWSMADHLANSWESSVGSQVEGDSIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVAAADGSSASPVKFYKVCVSVVSEKCRIDTEILPSLFMRCTTDPNRKDRFPAITHLKFLARDMSEQVLLCASSQTSSLVECWSLRKEGLPVNNIFQQISPVVGDKQPMILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASETQFYPGLGLVLAFQDGSVQMVHRLSLQTMAAFYSSTPRSLDEPTLKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGKLSMLRISPSLGHPLEPKLALQHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVERLHEEYTRQKPALQQVLSTRILAMKASLCKLSPCTVARVCDYHTKLFLMAITSTLKSLLRPHFLNTPDKSPGDRLAEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLVSLPNQGSPLRPGHSFLRDGTSLGTLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPASEPDEGLVDECCLLPSQLLVPSLDWLPASDGLVSRLQPKQPLRLRFGRAPTLPSNTSTLQLDGLARAPGQPKIDHLRRLHLGAYPTEECKACTRCGCVTMLKSPNKATAVKQWEQRWIKNCLCGGLWRRVPLSCP", "length": 865, "header": "tr|A0A9J7G3H8-1|A0A9J7G3H8_CRIGR Isoform 1 of Mediator of RNA polymerase II transcription subunit 16 OS=Cricetulus griseus OX=10029 GN=Med16 PE=3 SV=1 CANONICAL=A0A9J7G3H8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3J9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8/entry#A0A9J7G3J9-1", "sequence": { "sequence": "MAAPDPGRWGECGSRQPGRLGARSGQEPGTVLGAVGIMELVYVCEWENWAKNTYCPSLPLACAWSCRNLIAFTTDLRNDDQDLTHMIHILDTEHPWEVHSVNSGHSEAITCLEWDQSGSRLLSADADGHIKCWSMADHLANSWESSVGSQVEGDSIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVAAADGSSASPVKFYKVCVSVVSEKCRIDTEILPSLFMRCTTDPNRKDRFPAITHLKFLARDMSEQVLLCASSQTSSLVECWSLRKEGLPVNNIFQQISPVVGDKQPMILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASETQFYPGLGLVLAFQDGSVQMVHRLSLQTMAAFYSSTPRSLDEPTLKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGKLSMLRISPSLGHPLEPKLALQHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVERLHEEYTRQKPALQQVLSTRILAMKASLCKLSPCTVARVCDYHTKLFLMAITSTLKSLLRPHFLNTPDKSPGDRLAEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLVSLPNQGSPLRPGHSFLRDGTSLGTLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCETLCPLAVMRAQPVNPMRAWWMSAVCCPASCWCPAWTGFLPATAWSAACNPNSPCACASAGHLLCQATPPLCSWMALPGPLASQRSTTSGGCTWALTQLRSVKPAPGVAVSPC", "length": 837, "header": "tr|A0A9J7G3J9-1|A0A9J7G3J9_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 16 OS=Cricetulus griseus OX=10029 GN=Med16 PE=3 SV=1 CANONICAL=A0A9J7G3H8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8/entry#A0A9J7GZH3-1", "sequence": { "sequence": "MAAPDPGRWGECGSRQPGRLGARSGQEPGTVLGAVGIMELVYVCEWENWAKNTYCPSLPLACAWSCRNLIAFTTDLRNDDQGSRLLSADADGHIKCWSMADHLANSWESSVGSQVEGDSIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVAAADGSSASPVKFYKVCVSVVSEKCRIDTEILPSLFMRCTTDPNRKDRFPAITHLKFLARDMSEQVLLCASSQTSSLVECWSLRKEGLPVNNIFQQISPVVGDKQPMILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASETQFYPGLGLVLAFQDGSVQMVHRLSLQTMAAFYSSTPRSLDEPTLKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGKLSMLRISPSLGHPLEPKLALQHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVERLHEEYTRQKPALQQVLSTRILAMKASLCKLSPCTVARVCDYHTKLFLMAITSTLKSLLRPHFLNTPDKSPGDRLAEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLVSLPNQGSPLRPGHSFLRDGTSLGTLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPASEPDEGLVDECCLLPSQLLVPSLDWLPASDGLVSRLQPKQPLRLRFGRAPTLPSNTSTLQLDGLARAPGQPKIDHLRRLHLGAYPTEECKACTRCGCVTMLKSPNKATAVKQWEQRWIKNCLCGGLWRRVPLSCP", "length": 829, "header": "tr|A0A9J7GZH3-1|A0A9J7GZH3_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 16 OS=Cricetulus griseus OX=10029 GN=Med16 PE=3 SV=1 CANONICAL=A0A9J7G3H8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8/entry#A0A9J7JQF9-1", "sequence": { "sequence": "MELVYVCEWENWAKNTYCPSLPLACAWSCRNLIAFTTDLRNDDQDLTHMIHILDTEHPWEVHSVNSGHSEAITCLEWDQSGSRLLSADADGHIKCWSMADHLANSWESSVGSQVEGDSIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVAAADGSSASPVKFYKVCVSVVSEKCRIDTEILPSLFMRCTTDPNRKDRFPAITHLKFLARDMSEQVLLCASSQTSSLVECWSLRKEGLPVNNIFQQISPVVGDKQPMILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASETQFYPGLGLVLAFQDGSVQMVHRLSLQTMAAFYSSTPRSLDEPTLKRPRTTGPAVHFKAMQLSWTSLALVGIDNHGKLSMLRISPSLGHPLEPKLALQHLLFLLEYCMVTGYDWWDILLHVQPGMVQSLVERLHEEYTRQKPALQQVLSTRILAMKASLCKLSPCTVARVCDYHTKLFLMAITSTLKSLLRPHFLNTPDKSPGDRLAEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLVSLPNQGSPLRPGHSFLRDGTSLGTLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRDEGPASEPDEGLVDECCLLPSQLLVPSLDWLPASDGLVSRLQPKQPLRLRFGRAPTLPSNTSTLQLDGLARAPGQPKIDHLRRLHLGAYPTEECKACTRCGCVTMLKSPNKATAVKQWEQRWIKNCLCGGLWRRVPLSCP", "length": 828, "header": "tr|A0A9J7JQF9-1|A0A9J7JQF9_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 16 OS=Cricetulus griseus OX=10029 GN=Med16 PE=3 SV=1 CANONICAL=A0A9J7G3H8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 208, "start_aa": "Thr", "end_pos": 208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr208", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3H8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3H8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763586", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763586", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3H8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3H8" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3H8", "url": 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:: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273750" } ] }, { "annotation": "Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762687", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762687", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J5" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3J5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J5" }, { "id": "PF00326", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00326" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S9 prolyl oligopeptidase catalytic", "eco_id": "ECO_0000259", "start_pos": 484, "end_pos": 699, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G3J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3J5" }, { "id": "PF02897", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02897" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S9A N-terminal", "eco_id": "ECO_0000259", "start_pos": 102, "end_pos": 420, "start_aa": "Tyr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 48, "end_pos": 50 }, { "start_pos": 649, "end_pos": 651 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G4C1-1", "uniprot_ac": "A0A9J7G4C1", "uniprot_id": "A0A9J7G4C1_CRIGR", "mass": { "chemical_mass": 228854.0, "monoisotopic_mass": 228854.0 }, "refseq": { "ac": "XP_027276066", "name": "sodium channel protein type 1 subunit alpha isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276066" }, "gene_names": [ { "name": "Scn1a", "type": "recommended", "evidence": [ { "id": "A0A9J7G4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1" } ] }, { "name": "Scn1a", "type": "synonym", "evidence": [ { "id": "XP_027276066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276066" } ] } ], "protein_names": [ { "name": "Sodium channel protein", "type": "recommended", "evidence": [ { "id": "A0A9J7G4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1/entry#names_and_taxonomy" } ] }, { "name": "sodium channel protein type 1 subunit alpha isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027276066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276066" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276066" } ] }, { "annotation": "Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4E9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E9#function" }, { "database": "UniProtKB", "id": "RU361132", "url": "https://www.uniprot.org/uniprotkb/RU361132#function" }, { "database": "UniProtKB", "id": "A0A9J7G3K6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3K6#function" }, { "database": "UniProtKB", "id": "A0A9J7G4C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1#function" }, { "database": "UniProtKB", "id": "A0A9J7G7Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7Y5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Scn1a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1", "locus": {} } ], "crossref": [ { "id": "cd13433", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13433", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752032", "url": "https://www.ncbi.nlm.nih.gov/gene/100752032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752032", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G4C1", "url": "https://www.orthodb.org/?gene=A0A9J7G4C1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10037", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10037", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10037:SF280", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10037:SF280", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06512", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06512", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11933", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11933", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24609", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24609", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276066", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G3K6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3K6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4E9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7Y5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQTVLVPPGPDSFNFFTRESLAAIERRIAEEKAKNPKPDKKDDDENGPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYILTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKIIARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVQWPPTNASLEEHSIEKNITTDYNGTLVNETVFEFDWKSYIQDSRYHYFLEGFLDALLCGNSSDAGQCPEGYMCVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEAAQQAAAATASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDEDEFHKSESEDSVRRKGFRFSIEGNRLTYEKRYSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPRRHGERRNSNLSQTSRSSRMLAVFPANGKMHSTVDCNGVVSLVGGPSVPTSPVGQLLPEVIIDKPATDDNGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRAMSIASILTNTVEELEESRQKCPPCWYKFSNIFLIWDCSPYWLKVKHIVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNNVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIASDCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGIAYVKRKIYEFIQQSFVRKQKILDEIKPLDDLNNRKDNCISNHTTEIGKDLDCLKDVNGTTSGIGTGSSVEKYIIDESDYMSFINNPSLTVTVPIAVGESDFENLNTEDFSSESDLEESKEKLNESSSSSEGSTVDIGAPAEEQPVMEPEETLEPEACFTEGCVRRFKCCQISVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCVNTTTGDRFEITEVNNHSDCLKLIERNETARWKNVKVNFDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSDYVTSILSRINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAAALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRVQMEERFMASNPSKVSYQPITTTLKRKQEEVSAVIIQRAYRRHLLKRTVKQASFTYNKNKLKGGANLLVKEDMIIDRINENSITEKTDLTMSTAACPPSYDRVTKPIVEKHEQEGKDEKAKGK", "length": 2009, "header": "tr|A0A9J7G4C1-1|A0A9J7G4C1_CRIGR Isoform 1 of Sodium channel protein OS=Cricetulus griseus OX=10029 GN=Scn1a PE=3 SV=1 CANONICAL=A0A9J7G4C1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G3K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1/entry#A0A9J7G3K6-1", "sequence": { "sequence": "MMMKMAQSQTVTWKLGRTFHLSMETFLQRWCQSPWRTWTPTISTRKYTFTGIYTFESLIKIIARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVQWPPTNASLEEHSIEKNITTDYNGTLVNETVFEFDWKSYIQDSRYHYFLEGFLDALLCGNSSDAGQCPEGYMCVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEAAQQAAAATASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDEDEFHKSESEDSVRRKGFRFSIEGNRLTYEKRYSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPRRHGERRNSNLSQTSRSSRMLAVFPANGKMHSTVDCNGVVSLVGGPSVPTSPVGQLLPEVIIDKPATDDNGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRAMSIASILTNTVEELEESRQKCPPCWYKFSNIFLIWDCSPYWLKVKHIVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNNVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIASDCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGIAYVKRKIYEFIQQSFVRKQKILDEIKPLDDLNNRKDNCISNHTTEIGKDLDCLKDVNGTTSGIGTGSSVEKYIIDESDYMSFINNPSLTVTVPIAVGESDFENLNTEDFSSESDLEESKEKLNESSSSSEGSTVDIGAPAEEQPVMEPEETLEPEACFTEGCVRRFKCCQISVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCVNTTTGDRFEITEVNNHSDCLKLIERNETARWKNVKVNFDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSDYVTSILSRINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAAALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRVQMEERFMASNPSKVSYQPITTTLKRKQEEVSAVIIQRAYRRHLLKRTVKQASFTYNKNKLKGGANLLVKEDMIIDRINENSITEKTDLTMSTAACPPSYDRVTKPIVEKHEQEGKDEKAKGK", "length": 1897, "header": "tr|A0A9J7G3K6-1|A0A9J7G4C1_CRIGR Computationally mapped isoform of Sodium channel protein OS=Cricetulus griseus OX=10029 GN=Scn1a PE=3 SV=1 CANONICAL=A0A9J7G4C1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4C1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1/entry#A0A9J7G4C1-1", "sequence": { "sequence": "MEQTVLVPPGPDSFNFFTRESLAAIERRIAEEKAKNPKPDKKDDDENGPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYILTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKIIARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVQWPPTNASLEEHSIEKNITTDYNGTLVNETVFEFDWKSYIQDSRYHYFLEGFLDALLCGNSSDAGQCPEGYMCVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEAAQQAAAATASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDEDEFHKSESEDSVRRKGFRFSIEGNRLTYEKRYSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPRRHGERRNSNLSQTSRSSRMLAVFPANGKMHSTVDCNGVVSLVGGPSVPTSPVGQLLPEVIIDKPATDDNGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRAMSIASILTNTVEELEESRQKCPPCWYKFSNIFLIWDCSPYWLKVKHIVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNNVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIASDCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGIAYVKRKIYEFIQQSFVRKQKILDEIKPLDDLNNRKDNCISNHTTEIGKDLDCLKDVNGTTSGIGTGSSVEKYIIDESDYMSFINNPSLTVTVPIAVGESDFENLNTEDFSSESDLEESKEKLNESSSSSEGSTVDIGAPAEEQPVMEPEETLEPEACFTEGCVRRFKCCQISVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCVNTTTGDRFEITEVNNHSDCLKLIERNETARWKNVKVNFDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSDYVTSILSRINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAAALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRVQMEERFMASNPSKVSYQPITTTLKRKQEEVSAVIIQRAYRRHLLKRTVKQASFTYNKNKLKGGANLLVKEDMIIDRINENSITEKTDLTMSTAACPPSYDRVTKPIVEKHEQEGKDEKAKGK", "length": 2009, "header": "tr|A0A9J7G4C1-1|A0A9J7G4C1_CRIGR Isoform 1 of Sodium channel protein OS=Cricetulus griseus OX=10029 GN=Scn1a PE=3 SV=1 CANONICAL=A0A9J7G4C1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1/entry#A0A9J7G4E9-1", "sequence": { "sequence": "MEQTVLVPPGPDSFNFFTRESLAAIERRIAEEKAKNPKPDKKDDDENGPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYILTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKIIARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVQWPPTNASLEEHSIEKNITTDYNGTLVNETVFEFDWKSYIQDSRYHYFLEGFLDALLCGNSSDAGQCPEGYMCVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEAAQQAAAATASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDEDEFHKSESEDSVRRKGFRFSIEGNRLTYEKRYSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPRRHGERRNSNLSQTSRSSRMLAVFPANGKMHSTVDCNGVVSLVGGPSVPTSPVGQLLPEGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRAMSIASILTNTVEELEESRQKCPPCWYKFSNIFLIWDCSPYWLKVKHIVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNNVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIASDCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGIAYVKRKIYEFIQQSFVRKQKILDEIKPLDDLNNRKDNCISNHTTEIGKDLDCLKDVNGTTSGIGTGSSVEKYIIDESDYMSFINNPSLTVTVPIAVGESDFENLNTEDFSSESDLEESKEKLNESSSSSEGSTVDIGAPAEEQPVMEPEETLEPEACFTEGCVRRFKCCQISVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCVNTTTGDRFEITEVNNHSDCLKLIERNETARWKNVKVNFDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSDYVTSILSRINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAAALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRVQMEERFMASNPSKVSYQPITTTLKRKQEEVSAVIIQRAYRRHLLKRTVKQASFTYNKNKLKGGANLLVKEDMIIDRINENSITEKTDLTMSTAACPPSYDRVTKPIVEKHEQEGKDEKAKGK", "length": 1998, "header": "tr|A0A9J7G4E9-1|A0A9J7G4E9_CRIGR Computationally mapped isoform of Sodium channel protein OS=Cricetulus griseus OX=10029 GN=Scn1a PE=3 SV=1 CANONICAL=A0A9J7G4C1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1/entry#A0A9J7G7Y5-1", "sequence": { "sequence": "MIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEAAQQAAAATASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDEDEFHKSESEDSVRRKGFRFSIEGNRLTYEKRYSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPRRHGERRNSNLSQTSRSSRMLAVFPANGKMHSTVDCNGVVSLVGGPSVPTSPVGQLLPEVIIDKPATDDNGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRAMSIASILTNTVEELEESRQKCPPCWYKFSNIFLIWDCSPYWLKVKHIVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNNVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIASDCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGIAYVKRKIYEFIQQSFVRKQKILDEIKPLDDLNNRKDNCISNHTTEIGKDLDCLKDVNGTTSGIGTGSSVEKYIIDESDYMSFINNPSLTVTVPIAVGESDFENLNTEDFSSESDLEESKEKLNESSSSSEGSTVDIGAPAEEQPVMEPEETLEPEACFTEGCVRRFKCCQISVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCVNTTTGDRFEITEVNNHSDCLKLIERNETARWKNVKVNFDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSDYVTSILSRINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAAALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRVQMEERFMASNPSKVSYQPITTTLKRKQEEVSAVIIQRAYRRHLLKRTVKQASFTYNKNKLKGGANLLVKEDMIIDRINENSITEKTDLTMSTAACPPSYDRVTKPIVEKHEQEGKDEKAKGK", "length": 1610, "header": "tr|A0A9J7G7Y5-1|A0A9J7G7Y5_CRIGR Computationally mapped isoform of Sodium channel protein OS=Cricetulus griseus OX=10029 GN=Scn1a PE=3 SV=1 CANONICAL=A0A9J7G4C1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3K6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3K6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3K6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3K6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752032", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752032", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "neuronal action potential", "id": "GO:0019228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1" } ], "pmid": "" }, { "name": "membrane depolarization during action potential", "id": "GO:0086010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086010", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "voltage-gated sodium channel activity", "id": "GO:0005248", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005248", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "voltage-gated sodium channel complex", "id": "GO:0001518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001518", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4C1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1064, "end_pos": 1066, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1080, "end_pos": 1082, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1146, "end_pos": 1148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1378, "end_pos": 1380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1392, "end_pos": 1394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1403, "end_pos": 1405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1788, "end_pos": 1790, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 892, "end_pos": 894, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1" }, { "id": "PF00520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ion transport", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 432, "start_aa": "His", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1" }, { "id": "PF24609", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24609" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCN5A-like C-terminal IQ motif", "eco_id": "ECO_0000259", "start_pos": 1908, "end_pos": 1941, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1" }, { "id": "PF06512", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06512" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sodium ion transport-associated", "eco_id": "ECO_0000259", "start_pos": 1006, "end_pos": 1213, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G4C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C1" }, { "id": "PF11933", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11933" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Voltage-gated Na+ ion channel cytoplasmic", "eco_id": "ECO_0000259", "start_pos": 555, "end_pos": 718, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1064, "end_pos": 1066 }, { "start_pos": 1080, "end_pos": 1082 }, { "start_pos": 1146, "end_pos": 1148 }, { "start_pos": 1378, "end_pos": 1380 }, { "start_pos": 1392, "end_pos": 1394 }, { "start_pos": 1403, "end_pos": 1405 }, { "start_pos": 1788, "end_pos": 1790 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 621, "end_pos": 623 }, { "start_pos": 681, "end_pos": 683 }, { "start_pos": 892, "end_pos": 894 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G5M5-1", "uniprot_ac": "A0A9J7G5M5", "uniprot_id": "A0A9J7G5M5_CRIGR", "mass": { "chemical_mass": 204288.0, "monoisotopic_mass": 204288.0 }, "refseq": { "ac": "XP_007643405", "name": "protein Wiz isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643405" }, "gene_names": [ { "name": "Wiz", "type": "recommended", "evidence": [ { "id": "A0A9J7G5M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5" } ] }, { "name": "Wiz", "type": "synonym", "evidence": [ { "id": "XP_007643405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643405" } ] } ], "protein_names": [ { "name": "Protein Wiz", "type": "recommended", "evidence": [ { "id": "A0A9J7G5M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#names_and_taxonomy" } ] }, { "name": "Widely-interspaced zinc finger-containing protein", "type": "synonym", "evidence": [ { "id": "A0A9J7G5M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#names_and_taxonomy" } ] }, { "name": "protein Wiz isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007643405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643405" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614083.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007643405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643405" } ] }, { "annotation": "May link EHMT1 and EHMT2 histone methyltransferases to the CTBP corepressor machinery. May be involved in EHMT1-EHMT2 heterodimer formation and stabilization.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3L8#function" }, { "database": "UniProtKB", "id": "ARBA00057825", "url": "https://www.uniprot.org/uniprotkb/ARBA00057825#function" }, { "database": "UniProtKB", "id": "A0A9J7G3P1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3P1#function" }, { "database": "UniProtKB", "id": "A0A9J7G3P7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3P7#function" }, { "database": "UniProtKB", "id": "A0A9J7G5M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5#function" }, { "database": "UniProtKB", "id": "A0A9J7G826", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G826#function" }, { "database": "UniProtKB", "id": "A0A9J7JKB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKB7#function" }, { "database": "UniProtKB", "id": "A0A9J7JQI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQI0#function" }, { "database": "UniProtKB", "id": "A0A9J7K5V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5V0#function" }, { "database": "UniProtKB", "id": "A0A9J7GZG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZG4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wiz", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5", "locus": {} } ], "crossref": [ { "id": "100771986", "url": "https://www.ncbi.nlm.nih.gov/gene/100771986", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771986", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771986", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G5M5", "url": "https://www.orthodb.org/?gene=A0A9J7G5M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JQI0", "url": "https://www.orthodb.org/?gene=A0A9J7JQI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24396:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24396:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23015", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007643405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643405", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G3L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3P1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3P1", "database": "UniProtKB", "categories": [ 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYI2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K969", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K969", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K969-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K969-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISDGQPHPGLSEALPRATSATHRISSCYWDGDSLDFQPGSPPPHLLGPFPASLDVQGSWEHPMVQEAGEGIRSEQSFEDSVIVRTMKPHAKLKGSRKFLRHQGELKFLEKYPSSHHKLDWLQDANEQGPLKDAGLHLDLPAQPPTVTSFRRVIVPVDDTPKTLAMEFMGTREDLEDFAGLAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLISPVPTEPYLCELLQEVADGVDSHEEEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPPAELAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKRFPGDEGREARLQCPKCVFGTNSSRAFMQHAKLHMREILPNQQAKAPFRGGSPVIDVSTLVCPSYGDSSGLNTCIYCSFTAPSKNLLREHIRLIHAHAHWEEDGEAFEEILTSQPGTSQDTHIHFPDSVTTDYFSKSEPLLASMWQENPAGYDPGLAFGPDCQQAGMRDFSLLNSGQQPLGKLAFPSPMASASYPIQLNRNKSAVHLQRMDNKSRPWSDEEEEEDEDVVLTSEMDFTSENGAFPSPAITSLIPQSALELKQTFQDALQAAEASQDQQQQLQGMVPVVLVAKLRPQVMATASQASPKLTPEELGLGSNHPLDFLVIDTPLGDPLGLDTLLEGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDGLCSEENTMVAMDLGSPLLPKKSLPVSGTLEQVASRLSSKVAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRDGIQIRLPPGRGALAQLGRPPSASTALSLLPPPPPAKKAKLKASGMAIPWGKQDLSAAGIFWASDVEPSPLNLSSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1879, "header": "tr|A0A9J7G5M5-1|A0A9J7G5M5_CRIGR Isoform 1 of Protein Wiz OS=Cricetulus griseus OX=10029 GN=Wiz PE=3 SV=1 CANONICAL=A0A9J7G5M5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G3L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7G3L8-1", "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISDGQPHPGLSEALPRATSATHRISSCYWDGDSLDFQPGSPPPHLLGPFPASLDVQGSWEHPMVQEAGEGIRSEQSFEDSVIVRTMKPHAKLKGSRKFLRHQGELKFLEKYPSSHHKLDWLQDANEQGPLKDAGLHLDLPAQPPTVTSFRRVIVPVDDTPKTLAMEFMGTREDLEDFAGLAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLISPVPTEPYLCELLQEVADGVDSHEEEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPPAELAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKRFPGDEGREARLQCPKCVFGTNSSRAFMQHAKLHMREILPNQQAKAPFRGGSPVIDVSTLVCPSYGDSSGLNTCIYCSFTAPSKNLLREHIRLIHAHAHWEEDGEAFEEILTSQPGTSQDTHIHFPDSVTTDYFSKSEPLLASMWQENPAGYDPGLAFGPDCQQAGMRDFSLLNSGQQPLGKLAFPSPMASASYPIQLNRNKSAVHLQRMDNKSRPWSDEEEEEDEDVVLTSEMDFTSENGAFPSPAITSLIPQSALELKQTFQDALQAAEASQDQQQQLQGMVPVVLVAKLRPQVMATASQASPKLTPEELGLGSNHPLDFLVIDTPLGDPLGLDTLLEGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRDGIQIRLPPGRGALAQLGRPPSASTALSLLPPPPPAKKAKLKASGMAIPWGKQDLSAAGIFWASDVEPSPLNLSSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1822, "header": "tr|A0A9J7G3L8-1|A0A9J7G5M5_CRIGR Computationally mapped isoform of Protein Wiz OS=Cricetulus griseus OX=10029 GN=Wiz PE=3 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7G3P1-1", "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISDGQPHPGLSEALPRATSATHRISSCYWDGDSLDFQPGSPPPHLLGPFPASLDVQGSWEHPMVQEAGEGIRSEQSFEDSVIVRTMKPHAKLKGSRKFLRHQGELKFLEKYPSSHHKLDWLQDANEQGPLKDAGLHLDLPAQPPTVTSFRRVIVPVDDTPKTLAMEFMGTREDLEDFAGLAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLISPVPTEPYLCELLQEVADGVDSHEEEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPPAELAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKRFPGDEGREARLQCPKCVFGTNSSRAFMQHAKLHMREILPNQQAKAPFRGGSPVIDVSTLVCPSYGDSSGLNTCIYCSFTAPSKNLLREHIRLIHAHAHWEEDGEAFEEILTSQPGTSQDTHIHFPDSVTTDYFSKSEPLLASMWQENPAGYDPGLAFGPDCQQAGMRDFSLLNSGQQPLGKLAFPSPMASASYPIQLNRNKSAVHLQRMDNKSRPWSDEEEEEDEDVVLTSEMDFTSENGAFPSPAITSLIPQSALELKQTFQDALQAAEASQDQQQQLQGMVPVVLVAKLRPQVMATASQASPKLTPEELGLGSNHPLDFLVIDTPLGDPLGLDTLLEGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDGLCSEENTMVAMDLGSPLLPKKSLPVSGTLEQVASRLSSKVAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1749, "header": "tr|A0A9J7G3P1-1|A0A9J7G3P1_CRIGR Computationally mapped isoform of Protein Wiz OS=Cricetulus griseus OX=10029 GN=Wiz PE=3 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3P7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7G3P7-1", "sequence": { "sequence": "MLLKGKVIFFDLLITCLSPRKDHETFWMAEVAFLMGSPILASAKPSPVPPPLPIGSAAGECHAGPDLSYWDGDSLDFQPGSPPPHLLGPFPASLDVQGSWEHPMVQEAGEGIRSEQSFEDSVIVRTMKPHAKLKGSRKFLRHQGELKFLEKYPSSHHKLDWLQDANEQGPLKDAGLHLDLPAQPPTVTSFRRVIVPVDDTPKTLAMEFMGTREDLEDFAGLAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLISPVPTEPYLCELLQEVADGVDSHEEEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPPAELAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKRFPGDEGREARLQCPKCVFGTNSSRAFMQHAKLHMREILPNQQAKAPFRGGSPVIDVSTLVCPSYGDSSGLNTCIYCSFTAPSKNLLREHIRLIHAHAHWEEDGEAFEEILTSQPGTSQDTHIHFPDSVTTDYFSKSEPLLASMWQENPAGYDPGLAFGPDCQQAGMRDFSLLNSGQQPLGKLAFPSPMASASYPIQLNRNKSAVHLQRMDNKSRPWSDEEEEEDEDVVLTSEMDFTSENGAFPSPAITSLIPQSALELKQTFQDALQAAEASQDQQQQLQGMVPVVLVAKLRPQVMATASQASPKLTPEELGLGSNHPLDFLVIDTPLGDPLGLDTLLEGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDGLCSEENTMVAMDLGSPLLPKKSLPVSGTLEQVASRLSSKVAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRDGIQIRLPPGRGALAQLGRPPSASTALSLLPPPPPAKKAKLKASGMAIPWGKQDLSAAGIFWASDVEPSPLNLSSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1854, "header": "tr|A0A9J7G3P7-1|A0A9J7G3P7_CRIGR Computationally mapped isoform of Protein Wiz OS=Cricetulus griseus OX=10029 GN=Wiz PE=3 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G5M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7G5M5-1", "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISDGQPHPGLSEALPRATSATHRISSCYWDGDSLDFQPGSPPPHLLGPFPASLDVQGSWEHPMVQEAGEGIRSEQSFEDSVIVRTMKPHAKLKGSRKFLRHQGELKFLEKYPSSHHKLDWLQDANEQGPLKDAGLHLDLPAQPPTVTSFRRVIVPVDDTPKTLAMEFMGTREDLEDFAGLAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLISPVPTEPYLCELLQEVADGVDSHEEEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPPAELAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKRFPGDEGREARLQCPKCVFGTNSSRAFMQHAKLHMREILPNQQAKAPFRGGSPVIDVSTLVCPSYGDSSGLNTCIYCSFTAPSKNLLREHIRLIHAHAHWEEDGEAFEEILTSQPGTSQDTHIHFPDSVTTDYFSKSEPLLASMWQENPAGYDPGLAFGPDCQQAGMRDFSLLNSGQQPLGKLAFPSPMASASYPIQLNRNKSAVHLQRMDNKSRPWSDEEEEEDEDVVLTSEMDFTSENGAFPSPAITSLIPQSALELKQTFQDALQAAEASQDQQQQLQGMVPVVLVAKLRPQVMATASQASPKLTPEELGLGSNHPLDFLVIDTPLGDPLGLDTLLEGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDGLCSEENTMVAMDLGSPLLPKKSLPVSGTLEQVASRLSSKVAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRDGIQIRLPPGRGALAQLGRPPSASTALSLLPPPPPAKKAKLKASGMAIPWGKQDLSAAGIFWASDVEPSPLNLSSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1879, "header": "tr|A0A9J7G5M5-1|A0A9J7G5M5_CRIGR Isoform 1 of Protein Wiz OS=Cricetulus griseus OX=10029 GN=Wiz PE=3 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G826-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7G826-1", "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISDGQPHPGLSEALPRATSATHRISSCYWDGDSLDFQPGSPPPHLLGPFPASLDVQGSWEHPMVQEAGEGIRSEQSFEDSVIVRTMKPHAKLKGSRKFLRHQGELKFLEKYPSSHHKLDWLQDANEQGPLKDAGLHLDLPAQPPTVTSFRRVIVPVDDTPKTLAMEFMGTREDLEDFAGLAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLISPVPTEPYLCELLQEVADGVDSHEEEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPPAELAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKRFPGDEGREARLQCPKCVFGTNSSRAFMQHAKLHMREILPNQQAKAPFRGGSPVIDVSTLVCPSYGDSSGLNTCIYCSFTAPSKNLLREHIRLIHAHAHWEEDGEAFEEILTSQPGTSQDTHIHFPDSVTTDYFSKSEPLLASMWQENPAGYDPGLAFGPDCQQAGMRDFSLLNSGQQPLGKLAFPSPMASASYPIQLNRNKSAVHLQRMDNKSRPWSDEEEEEDEDVVLTSEMDFTSENGAFPSPAITSLIPQSALELKQTFQDALQAAEASQDQQQQLQGMVPVVLVAKLRPQVMATASQASPKLTPEELGLGSNHPLDFLVIDTPLGDPLGLDTLLEGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDGLCSEENTMVAMDLGSPLLPKKSLPVSGTLEQVASRLSSKVAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRDGIQIRLPPGRGALAQLGRPPSASTALSLLPPPPPAKKAKLKASASGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1850, "header": "tr|A0A9J7G826-1|A0A9J7G826_CRIGR Computationally mapped isoform of Protein Wiz OS=Cricetulus griseus OX=10029 GN=Wiz PE=3 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7GZG4-1", "sequence": { "sequence": "MPGLEYGQPHPGLSEALPRATSATHRISSCYWDGDSLDFQPGSPPPHLLGPFPASLDVQGSWEHPMVQEAGEGIRSEQSFEDSVIVRTMKPHAKLKGSRKFLRHQGELKFLEKYPSSHHKLDWLQDANEQGPLKDAGLHLDLPAQPPTVTSFRRVIVPVDDTPKTLAMEFMGTREDLEDFAGLAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLISPVPTEPYLCELLQEVADGVDSHEEEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPPAELAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKRFPGDEGREARLQCPKCVFGTNSSRAFMQHAKLHMREILPNQQAKAPFRGGSPVIDVSTLVCPSYGDSSGLNTCIYCSFTAPSKNLLREHIRLIHAHAHWEEDGEAFEEILTSQPGTSQDTHIHFPDSVTTDYFSKSEPLLASMWQENPAGYDPGLAFGPDCQQAGMRDFSLLNSGQQPLGKLAFPSPMASASYPIQLNRNKSAVHLQRMDNKSRPWSDEEEEEDEDVVLTSEMDFTSENGAFPSPAITSLIPQSALELKQTFQDALQAAEASQDQQQQLQGMVPVVLVAKLRPQVMATASQASPKLTPEELGLGSNHPLDFLVIDTPLGDPLGLDTLLEGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDGLCSEENTMVAMDLGSPLLPKKSLPVSGTLEQVASRLSSKVAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRDGIQIRLPPGRGALAQLGRPPSASTALSLLPPPPPAKKAKLKASGMAIPWGKQDLSAAGIFWASDVEPSPLNLSSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1816, "header": "tr|A0A9J7GZG4-1|A0A9J7GZG4_CRIGR Computationally mapped isoform of Protein Wiz OS=Cricetulus griseus OX=10029 GN=Wiz PE=3 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7GZT6-1", "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDGLCSEENTMVAMDLGSPLLPKKSLPVSGTLEQVASRLSSKVAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRDGIQIRLPPGRGALAQLGRPPSASTALSLLPPPPPAKKAKLKASGMAIPWGKQDLSAAGIFWASDVEPSPLNLSSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1149, "header": "tr|A0A9J7GZT6-1|A0A9J7GZT6_CRIGR Computationally mapped isoform of Protein Wiz isoform X14 OS=Cricetulus griseus OX=10029 GN=Wiz PE=4 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7JKB7-1", "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISDGQPHPGLSEALPRATSATHRISSCYWDGDSLDFQPGSPPPHLLGPFPASLDVQGSWEHPMVQEAGEGIRSEQSFEDSVIVRTMKPHAKLKGSRKFLRHQGELKFLEKYPSSHHKLDWLQDANEQGPLKDAGLHLDLPAQPPTVTSFRRVIVPVDDTPKTLAMEFMGTREDLEDFAGLAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLISPVPTEPYLCELLQEVADGVDSHEEEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPPAELAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKRFPGDEGREARLQCPKCVFGTNSSRAFMQHAKLHMREILPNQQAKAPFRGGSPVIDVSTLVCPSYGDSSGLNTCIYCSFTAPSKNLLREHIRLIHAHAHWEEDGEAFEEILTSQPGTSQDTHIHFPDSVTTDYFSKSEPLLASMWQENPAGYDPGLAFGPDCQQAGMRDFSLLNSGQQPLGKLAFPSPMASASYPIQLNRNKSAVHLQRMDNKSRPWSDEEEEEDEDVVLTSEMDFTSENGAFPSPAITSLIPQSALELKQTFQDALQAAEASQDQQQQLQGMVPVVLVAKLRPQVMATASQASPKLTPEELGLGSNHPLDFLVIDTPLGDPLGLDTLLEGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1692, "header": "tr|A0A9J7JKB7-1|A0A9J7JKB7_CRIGR Computationally mapped isoform of Protein Wiz OS=Cricetulus griseus OX=10029 GN=Wiz PE=3 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7JQI0-1", "sequence": { "sequence": "MVQEAGEGIRSEQSFEDSVIVRTMKPHAKLKGSRKFLRHQGELKFLEKYPSSHHKLDWLQDANEQGPLKDAGLHLDLPAQPPTVTSFRRVIVPVDDTPKTLAMEFMGTREDLEDFAGLAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLISPVPTEPYLCELLQEVADGVDSHEEEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPPAELAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKRFPGDEGREARLQCPKCVFGTNSSRAFMQHAKLHMREILPNQQAKAPFRGGSPVIDVSTLVCPSYGDSSGLNTCIYCSFTAPSKNLLREHIRLIHAHAHWEEDGEAFEEILTSQPGTSQDTHIHFPDSVTTDYFSKSEPLLASMWQENPAGYDPGLAFGPDCQQAGMRDFSLLNSGQQPLGKLAFPSPMASASYPIQLNRNKSAVHLQRMDNKSRPWSDEEEEEDEDVVLTSEMDFTSENGAFPSPAITSLIPQSALELKQTFQDALQAAEASQDQQQQLQGMVPVVLVAKLRPQVMATASQASPKLTPEELGLGSNHPLDFLVIDTPLGDPLGLDTLLEGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDGLCSEENTMVAMDLGSPLLPKKSLPVSGTLEQVASRLSSKVAAEVPHGSKQELPDLKAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRDGIQIRLPPGRGALAQLGRPPSASTALSLLPPPPPAKKAKLKASGMAIPWGKQDLSAAGIFWASDVEPSPLNLSSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1751, "header": "tr|A0A9J7JQI0-1|A0A9J7JQI0_CRIGR Computationally mapped isoform of Protein Wiz OS=Cricetulus griseus OX=10029 GN=Wiz PE=3 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7JYI2-1", "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTLDSDGGRELDCQLCGAWFETRKGLSSHARAHLRHLGVSDPDAKGSPIDVLHGLIRRDGIQIRLPPGRGALAQLGRPPSASTALSLLPPPPPAKKAKLKASGMAIPWGKQDLSAAGIFWASDVEPSPLNLSSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1092, "header": "tr|A0A9J7JYI2-1|A0A9J7JYI2_CRIGR Computationally mapped isoform of Protein Wiz isoform X3 OS=Cricetulus griseus OX=10029 GN=Wiz PE=4 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7K5V0-1", "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISDGQPHPGLSEALPRATSATHRISSCYWDGDSLDFQPGSPPPHLLGPFPASLDVQGSWEHPMVQEAGEGIRSEQSFEDSVIVRTMKPHAKLKGSRKFLRHQGELKFLEKYPSSHHKLDWLQDANEQGPLKDAGLHLDLPAQPPTVTSFRRVIVPVDDTPKTLAMEFMGTREDLEDFAGLAQPSEWGLHTSASEVATQTWTVNSEASVERLQPLISPVPTEPYLCELLQEVADGVDSHEEEEEEEEPAVFPCIECSIYFKHKEHLLEHMSQHRRAPGQEPPAELAPLACSECGWAFTEPTALEQHWQLHQASREKIIEEIQKLKRFPGDEGREARLQCPKCVFGTNSSRAFMQHAKLHMREILPNQQAKAPFRGGSPVIDVSTLVCPSYGDSSGLNTCIYCSFTAPSKNLLREHIRLIHAHAHWEEDGEAFEEILTSQPGTSQDTHIHFPDSVTTDYFSKSEPLLASMWQENPAGYDPGLAFGPDCQQAGMRDFSLLNSGQQPLGKLAFPSPMASASYPIQLNRNKSAVHLQRMDNKSRPWSDEEEEEDEDVVLTSEMDFTSENGAFPSPAITSLIPQSALELKQTFQDALQAAEASQDQQQQLQGMVPVVLVAKLRPQVMATASQASPKLTPEELGLGSNHPLDFLVIDTPLGDPLGLDTLLEGDPAMALKHEERKCPYCPDRFHNGIGLANHVRGHLNRVGVSYNVRHFISAEEVKAIERRFSFQKKKKKVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDASGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 1524, "header": "tr|A0A9J7K5V0-1|A0A9J7K5V0_CRIGR Computationally mapped isoform of Protein Wiz OS=Cricetulus griseus OX=10029 GN=Wiz PE=3 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K7S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7K7S6-1", "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDASGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 794, "header": "tr|A0A9J7K7S6-1|A0A9J7K7S6_CRIGR Computationally mapped isoform of Protein Wiz isoform X5 OS=Cricetulus griseus OX=10029 GN=Wiz PE=4 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K969-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5/entry#A0A9J7K969-1", "sequence": { "sequence": "MEGVLAGGLAAPDHPRGPERLPGPAPREDIEGGTDAAEGEGDIFRSAHYLPITKEGPRDILDGRSGISVANFDPGTFSLMRCDFCGAGFDTRAGLSSHARAHLRDFGITNWELTISPINILQELLATSAAELPPSPLDHEPSVPPGSFLTSRRPRLPLTMPFPPTWAEDPGPIYGDAQSLTTCEVCGACFETRKGLSSHARSHLRQLGVAESESSGAPIDLLYELVKQKGLPDAPLGLPPSLTKKSNSPKELVAGATRPGLLSLAKPMDAPAVNKAIKSPPGFSAKGLAHPSSSPVLKKAPLTLAGSPTPKNPEDKSPQLSLSPRPTSPKAQWSQSEDEGPLNLTSGPEPTRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWYVNGSPIDTLREILKRRTQSRPGGHLHPPGPSPKTLAKVVGSGGPGSSLEAHSPSDLHISPLAKKLPPPPGSPLGHSPTASPPPTARKMFSGLATPSLPKKLKPEQMRVEIKREMPPGSLHGEPHPPEGPWGTPREDLAPLNLSSRAEPVRDIRCEFCGEFFENRKGLSSHARSHLRQMGVTEWSVNGSPIDTLREILKKKSKLCLIKKEPPAGDLAPALAEDGSPTAAPGAMHSPLPLSPLASRPGKPGAGPTQVPRELSLSPISGAKPSATSYMGSVATKRPLQEDHFLPAEVKTKTYIQTELPFKAKTLHEKTSHSSTEACCELCGLYFENRKALASHARAHLRQFGVTEWCVNGSPIETLSEWIKHRPQKAGAYRSYIQGGRPFTKKFRSAGHGRDSDKRPPLGLAPGGLSLVGRSAGGEPGPEAGRAADSGERPLATSPPGTVKSEEHQRQNINKFERRQARPPDASAARGGEEANDLQQKLEEVRQPPPRVRPVPSLVPRPPQTSLVKFVGNIYTLKCRFCEVEFQGPLSIQEDWVRHLQRHILEMNFSKADPPPEEPQAPQAQTAAVEAP", "length": 962, "header": "tr|A0A9J7K969-1|A0A9J7K969_CRIGR Computationally mapped isoform of Protein Wiz isoform X4 OS=Cricetulus griseus OX=10029 GN=Wiz PE=4 SV=1 CANONICAL=A0A9J7G5M5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1397, "start_aa": "Thr", "end_pos": 1397, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1397", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1556, "start_aa": "Thr", "end_pos": 1556, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1556", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3L8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3L8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771986", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771986", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5" } ], "pmid": "" }, { "name": "histone methyltransferase binding", "id": "GO:1990226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5M5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1130, "end_pos": 1132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1260, "end_pos": 1262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1305, "end_pos": 1307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1444, "end_pos": 1446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1489, "end_pos": 1491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1659, "end_pos": 1661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1855, "end_pos": 1857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G5M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5M5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 338, "start_aa": "Phe", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1397, 1556 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1130, "end_pos": 1132 }, { "start_pos": 1260, "end_pos": 1262 }, { "start_pos": 1305, "end_pos": 1307 }, { "start_pos": 1444, "end_pos": 1446 }, { "start_pos": 1489, "end_pos": 1491 }, { "start_pos": 1659, "end_pos": 1661 }, { "start_pos": 1855, "end_pos": 1857 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 591, "end_pos": 593 }, { "start_pos": 602, "end_pos": 604 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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{ "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G3Y8-1", "uniprot_ac": "A0A9J7G3Y8", "uniprot_id": "A0A9J7G3Y8_CRIGR", "mass": { "chemical_mass": 178640.0, "monoisotopic_mass": 178640.0 }, "refseq": { "ac": "XP_027275507", "name": "bromodomain adjacent to zinc finger domain protein 1A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275507" }, "gene_names": [ { "name": "Baz1a", "type": "recommended", "evidence": [ { "id": "A0A9J7G3Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ] }, { "name": "Baz1a", "type": "synonym", "evidence": [ { "id": "XP_027275507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275507" } ] } ], "protein_names": [ { "name": "Bromodomain adjacent to zinc finger domain protein 1A", "type": "recommended", "evidence": [ { "id": "A0A9J7G3Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8/entry#names_and_taxonomy" } ] }, { "name": "bromodomain adjacent to zinc finger domain protein 1A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027275507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275507" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275507" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Baz1a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8", "locus": {} } ], "crossref": [ { "id": "cd05504", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05504", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15627", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15627", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757354", "url": "https://www.ncbi.nlm.nih.gov/gene/100757354", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757354", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757354", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G3Y8", "url": "https://www.orthodb.org/?gene=A0A9J7G3Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46510", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46510", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46510:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46510:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10537", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10537", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15613", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15613", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275507", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G3M4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKF2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTR0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLLHRKPFVRQKPPGDLRPDEEVFHCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPGLTYQEALESEKKARQNLQSFPEPLIIPVLYLTNLTHRSRLHEICDDIFAYVKDRYFVEETVEVIRNNGTRLQCRILEVLPPLHQNGFANGHVGSVDGETIVISDSDDSETQSSSFQHGKKKDAVDPLLFRYRVQPTKKEIYESAVVKATQISRRKHLFSRDKLKLFLKQHCEPQDGIIKIKASSLSTYNIAEQDFSYFFPDDPPTFIFSPVNRRRGRPPKRLSLGQEDNIASKQTIAGCRSKATKERDKLLKQEEMKALVLNLTFPKAFEKAKLKREKADALEARKKEKEDKEKKREELKKIVEEERLKKKEEKERLKIEREKEREKLREEKRKYMEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPEGVTLEVLEEALVGNDSEGPLCELLFFFLTAIFQAMAEEEEEVAKEQITDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSSPSLVKKLSSTAVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDVLRQAKQEFRELKAEQHRKEREATAARIRRRKEEKLKEQEQKMKEKQEKLKEDEQRNSAADLGEEGKEDFDTSIESKETEQKDLDPDMVTEDEDDPGSQRRSRRGKAGQSGVKQCIKQEEINCCIKQEPLAADTEEALRQEHQRKEKELLDKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDFSGLTEDMLLPRPSSFHDNAQSHNAQVSVKTEESFMSESTSSLDQGPFDDSILLPKPVHKPNRWCFYSSEDQLDQLIEALNSRGHRESALKDTLLQEKSRICAQLAHFSEEKFHFSDNPQADTKPVSSRGRSSNVCDTSQMSAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRQIWRSALENGRYELLSEENKENGVIKTINEDAEEMEVEQARVIVRDRLLGIKTETPSAVSTNSSTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDGSDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVMWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEEVEENMEGDNEVDDDDEEGQSEEEEYEVEQDEEDSEEEELSPPKRGRPQVRLPIKTRGRLSSSFSSRNQRQDHGRYPSRSQHSTPKTTASPKTSGRSLRKIRSAPSTETRSLRIASRSTRHSPGTLQADVFVELLSPPGKRKVRKSADNTQEHSPSFTNFKVSTSRSSGQLTPLNTATGLSLQDSESKRRGRKRQSTESSPVPLNRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHYQAQKLGLHVSSSSVDQVSVPVAAKKSRV", "length": 1561, "header": "tr|A0A9J7G3Y8-1|A0A9J7G3Y8_CRIGR Isoform 1 of Bromodomain adjacent to zinc finger domain protein 1A OS=Cricetulus griseus OX=10029 GN=Baz1a PE=3 SV=1 CANONICAL=A0A9J7G3Y8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G3M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8/entry#A0A9J7G3M4-1", "sequence": { "sequence": "MPLLHRKPFVRQKPPGDLRPDEEVFHCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPGLTYQEALESEKKARQNLQSFPEPLIIPVLYLTNLTHRSRLHEICDDIFAYVKDRYFVEETVEVIRNNGTRLQCRILEVLPPLHQNGFANGHVGSVDGETIVISDSDDSETQSSSFQHGKKKDAVDPLLFRYRVQPTKKEIYESAVVKATQISRRKHLFSRDKLKLFLKQHCEPQDGIIKIKASSLSTYNIAEQDFSYFFPDDPPTFIFSPVNRRRGRPPKRLSLGQEDNIASKQTIAGCRSKATKERDKLLKQEEMKALAFEKAKLKREKADALEARKKEKEDKEKKREELKKIVEEERLKKKEEKERLKIEREKEREKLREEKRKYMEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPEGVTLEVLEEALVGNDSEGPLCELLFFFLTAIFQAMAEEEEEVAKEQITDADTKGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSSPSLVKKLSSTAVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDVLRQAKQEFRELKAEQHRKEREATAARIRRRKEEKLKEQEQKMKEKQEKLKEDEQRNSAADLGEEGKEDFDTSIESKETEQKDLDPDMVTEDEDDPGSQRRSRRGKAGQSGVKQCIKQEEINCCIKQEPLAADTEEALRQEHQRKEKELLDKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDFSGLTEDMLLPRPSSFHDNAQSHNAQVSVKTEESFMSESTSSLDQGPFDDSILLPKPVHKPNRWCFYSSEDQLDQLIEALNSRGHRESALKDTLLQEKSRICAQLAHFSEEKFHFSDNPQADTKPVSSRGRSSNVCDTSQMSAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRQIWRSALENGRYELLSEENKENGVIKTINEDAEEMEVEQARVIVRDRLLGIKTETPSAVSTNSSTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDGSDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVMWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEEVEENMEGDNEVDDDDEEGQSEEEEYEVEQDEEDSEEEELSPPKRGRPQVRLPIKTRGRLSSSFSSRNQRQDHGRYPSRSQHSTPKTTASPKTSGRSLRKIRSAPSTETRSLRIASRSTRHSPGTLQADVFVELLSPPGKRKVRKSADNTQEHSPSFTNFKVSTSRSSGQLTPLNTATGLSLQDSESKRRGRKRQSTESSPVPLNRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHYQAQKLGLHVSSSSVDQVSVPVAAKKSRV", "length": 1521, "header": "tr|A0A9J7G3M4-1|A0A9J7G3Y8_CRIGR Computationally mapped isoform of Bromodomain adjacent to zinc finger domain protein 1A OS=Cricetulus griseus OX=10029 GN=Baz1a PE=3 SV=1 CANONICAL=A0A9J7G3Y8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8/entry#A0A9J7G3Y8-1", "sequence": { "sequence": "MPLLHRKPFVRQKPPGDLRPDEEVFHCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPGLTYQEALESEKKARQNLQSFPEPLIIPVLYLTNLTHRSRLHEICDDIFAYVKDRYFVEETVEVIRNNGTRLQCRILEVLPPLHQNGFANGHVGSVDGETIVISDSDDSETQSSSFQHGKKKDAVDPLLFRYRVQPTKKEIYESAVVKATQISRRKHLFSRDKLKLFLKQHCEPQDGIIKIKASSLSTYNIAEQDFSYFFPDDPPTFIFSPVNRRRGRPPKRLSLGQEDNIASKQTIAGCRSKATKERDKLLKQEEMKALVLNLTFPKAFEKAKLKREKADALEARKKEKEDKEKKREELKKIVEEERLKKKEEKERLKIEREKEREKLREEKRKYMEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPEGVTLEVLEEALVGNDSEGPLCELLFFFLTAIFQAMAEEEEEVAKEQITDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSSPSLVKKLSSTAVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDVLRQAKQEFRELKAEQHRKEREATAARIRRRKEEKLKEQEQKMKEKQEKLKEDEQRNSAADLGEEGKEDFDTSIESKETEQKDLDPDMVTEDEDDPGSQRRSRRGKAGQSGVKQCIKQEEINCCIKQEPLAADTEEALRQEHQRKEKELLDKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDFSGLTEDMLLPRPSSFHDNAQSHNAQVSVKTEESFMSESTSSLDQGPFDDSILLPKPVHKPNRWCFYSSEDQLDQLIEALNSRGHRESALKDTLLQEKSRICAQLAHFSEEKFHFSDNPQADTKPVSSRGRSSNVCDTSQMSAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRQIWRSALENGRYELLSEENKENGVIKTINEDAEEMEVEQARVIVRDRLLGIKTETPSAVSTNSSTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDGSDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVMWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEEVEENMEGDNEVDDDDEEGQSEEEEYEVEQDEEDSEEEELSPPKRGRPQVRLPIKTRGRLSSSFSSRNQRQDHGRYPSRSQHSTPKTTASPKTSGRSLRKIRSAPSTETRSLRIASRSTRHSPGTLQADVFVELLSPPGKRKVRKSADNTQEHSPSFTNFKVSTSRSSGQLTPLNTATGLSLQDSESKRRGRKRQSTESSPVPLNRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHYQAQKLGLHVSSSSVDQVSVPVAAKKSRV", "length": 1561, "header": "tr|A0A9J7G3Y8-1|A0A9J7G3Y8_CRIGR Isoform 1 of Bromodomain adjacent to zinc finger domain protein 1A OS=Cricetulus griseus OX=10029 GN=Baz1a PE=3 SV=1 CANONICAL=A0A9J7G3Y8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8/entry#A0A9J7JKF2-1", "sequence": { "sequence": "MPLLHRKPFVRQKPPGDLRPDEEVFHCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPGLTYQEALESEKKARQNLQSFPEPLIIPVLYLTNLTHRSRLHEICDDIFAYVKDRYFVEETVEVIRNNGTRLQCRILEVLPPLHQNGFANGHVGSVDGETIVISDSDDSETQSSSFQHGKKKDAVDPLLFRYRVQPTKKEIYESAVVKATQIRRKHLFSRDKLKLFLKQHCEPQDGIIKIKASSLSTYNIAEQDFSYFFPDDPPTFIFSPVNRRRGRPPKRLSLGQEDNIASKQTIAGCRSKATKERDKLLKQEEMKALVLNLTFPKAFEKAKLKREKADALEARKKEKEDKEKKREELKKIVEEERLKKKEEKERLKIEREKEREKLREEKRKYMEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPEGVTLEVLEEALVGNDSEGPLCELLFFFLTAIFQAMAEEEEEVAKEQITDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSSPSLVKKLSSTAVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDVLRQAKQEFRELKAEQHRKEREATAARIRRRKEEKLKEQEQKMKEKQEKLKEDEQRNSAADLGEEGKEDFDTSIESKETEQKDLDPDMVTEDEDDPGSQRRSRRGKAGQSGVKQCIKQEEINCCIKQEPLAADTEEALRQEHQRKEKELLDKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDFSGLTEDMLLPRPSSFHDNAQSHNAQVSVKTEESFMSESTSSLDQGPFDDSILLPKPVHKPNRWCFYSSEDQLDQLIEALNSRGHRESALKDTLLQEKSRICAQLAHFSEEKFHFSDNPQADTKPVSSRGRSSNVCDTSQMSAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRQIWRSALENGRYELLSEENKENGVIKTINEDAEEMEVEQARVIVRDRLLGIKTETPSAVSTNSSTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDGSDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVMWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEEVEENMEGDNEVDDDDEEGQSEEEEYEVEQDEEDSEEEELSPPKRGRPQVRLPIKTRGRLSSSFSSRNQRQDHGRYPSRSQHSTPKTTASPKTSGRSLRKIRSAPSTETRSLRIASRSTRHSPGTLQADVFVELLSPPGKRKVRKSADNTQEHSPSFTNFKVSTSRSSGQLTPLNTATGLSLQDSESKRRGRKRQSTESSPVPLNRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHYQAQKLGLHVSSSSVDQVSVPVAAKKSRV", "length": 1560, "header": "tr|A0A9J7JKF2-1|A0A9J7JKF2_CRIGR Computationally mapped isoform of Bromodomain adjacent to zinc finger domain protein 1A OS=Cricetulus griseus OX=10029 GN=Baz1a PE=3 SV=1 CANONICAL=A0A9J7G3Y8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8/entry#A0A9J7JSE9-1", "sequence": { "sequence": "MPLLHRKPFVRQKPPGDLRPDEEVFHCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPGLTYQEALESEKKARQNLQSFPEPLIIPVLYLTNLTHRSRLHEICDDIFAYVKDRYFVEETVEVIRNNGTRLQCRILEVLPPLHQNGFANGHVGSVDGETIVISDSDDSETQSSSFQHGKKKDAVDPLLFRYRVQPTKKEIYESAVVKATQISRRKHLFSRDKLKLFLKQHCEPQDGIIKIKASSLSTYNIAEQDFSYFFPDDPPTFIFSPVNRRRGRPPKRLSLGQEDNIASKQTIAGCRSKATKERDKLLKQEEMKALVLNLTFPKAFEKAKLKREKADALEARKKEKEDKEKKREELKKIVEEERLKKKEEKERLKIEREKEREKLREEKRKYMEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPEGVTLEVLEEALVGNDSEGPLCELLFFFLTAIFQAMAEEEEEVAKEQITDADTKGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSSPSLVKKLSSTAVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDVLRQAKQEFRELKAEQHRKEREATAARIRRRKEEKLKEQEQKMKEKQEKLKEDEQRNSAADLGEEGKEDFDTSIESKETEQKDLDPDMVTEDEDDPGSQRRSRRGKAGQSGVKQCIKQEEINCCIKQEPLAADTEEALRQEHQRKEKELLDKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDFSGLTEDMLLPRPSSFHDNAQSHNAQVSVKTEESFMSESTSSLDQGPFDDSILLPKPVHKPNRWCFYSSEDQLDQLIEALNSRGHRESALKDTLLQEKSRICAQLAHFSEEKFHFSDNPQADTKPVSSRGRSSNVCDTSQMSAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRQIWRSALENGRYELLSEENKENGVIKTINEDAEEMEVEQARVIVRDRLLGIKTETPSAVSTNSSTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDGSDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVMWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEEVEENMEGDNEVDDDDEEGQSEEEEYEVEQDEEDSEEEELSPPKRGRPQVRLPIKTRGRLSSSFSSRNQRQDHGRYPSRSQHSTPKTTASPKTSGRSLRKIRSAPSTETRSLRIASRSTRHSPGTLQADVFVELLSPPGKRKVRKSADNTQEHSPSFTNFKVSTSRSSGQLTPLNTATGLSLQDSESKRRGRKRQSTESSPVPLNRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHYQAQKLGLHVSSSSVDQVSVPVAAKKSRV", "length": 1529, "header": "tr|A0A9J7JSE9-1|A0A9J7JSE9_CRIGR Computationally mapped isoform of Bromodomain adjacent to zinc finger domain protein 1A OS=Cricetulus griseus OX=10029 GN=Baz1a PE=3 SV=1 CANONICAL=A0A9J7G3Y8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8/entry#A0A9J7JTR0-1", "sequence": { "sequence": "MPLLHRKPFVRQKPPGDLRPDEEVFHCKVTNEIFRHYDDFFERTILCNSLVWSCAVTGRPGLTYQEALESEKKARQNLQSFPEPLIIPVLYLTNLTHRSRLHEICDDIFAYVKDRYFVEETVEVIRNNGTRLQCRILEVLPPLHQNGFANGHVGSVDGETIVISDSDDSETQSSSFQHGKKKDAVDPLLFRYRVQPTKKEIYESAVVKATQISRRKHLFSRDKLKLFLKQHCEPQDGIIKIKASSLSTYNIAEQDFSYFFPDDPPTFIFSPVNRRRGRPPKRLSLGQEDNIASKQTIAGCRSKATKERDKLLKQEEMKALAFEKAKLKREKADALEARKKEKEDKEKKREELKKIVEEERLKKKEEKERLKIEREKEREKLREEKRKYMEYLKQWSKPREDMECDDLKELPEPTPVKTRLPPEIFGDALMVLEFLNAFGELFDLQDEFPEGVTLEVLEEALVGNDSEGPLCELLFFFLTAIFQAMAEEEEEVAKEQITDADTKDLTEALDEDADPTKSALSAVASLAAAWPQLHQGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMELRLSSPSLVKKLSSTAVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDVLRQAKQEFRELKAEQHRKEREATAARIRRRKEEKLKEQEQKMKEKQEKLKEDEQRNSAADLGEEGKEDFDTSIESKETEQKDLDPDMVTEDEDDPGSQRRSRRGKAGQSGVKQCIKQEEINCCIKQEPLAADTEEALRQEHQRKEKELLDKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIEEDFSGLTEDMLLPRPSSFHDNAQSHNAQVSVKTEESFMSESTSSLDQGPFDDSILLPKPVHKPNRWCFYSSEDQLDQLIEALNSRGHRESALKDTLLQEKSRICAQLAHFSEEKFHFSDNPQADTKPVSSRGRSSNVCDTSQMSAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRQIWRSALENGRYELLSEENKENGVIKTINEDAEEMEVEQARVIVRDRLLGIKTETPSAVSTNSSTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDGSDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVMWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEEVEENMEGDNEVDDDDEEGQSEEEEYEVEQDEEDSEEEELSPPKRGRPQVRLPIKTRGRLSSSFSSRNQRQDHGRYPSRSQHSTPKTTASPKTSGRSLRKIRSAPSTETRSLRIASRSTRHSPGTLQADVFVELLSPPGKRKVRKSADNTQEHSPSFTNFKVSTSRSSGQLTPLNTATGLSLQDSESKRRGRKRQSTESSPVPLNRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFFHYQAQKLGLHVSSSSVDQVSVPVAAKKSRV", "length": 1553, "header": "tr|A0A9J7JTR0-1|A0A9J7JTR0_CRIGR Computationally mapped isoform of Bromodomain adjacent to zinc finger domain protein 1A OS=Cricetulus griseus OX=10029 GN=Baz1a PE=3 SV=1 CANONICAL=A0A9J7G3Y8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 422, "start_aa": "Thr", "end_pos": 422, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr422", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3M4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3M4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3M4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3M4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757354", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757354", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ], "pmid": "" }, { "name": "positive regulation of DNA replication", "id": "GO:0045740", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045740", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ], "pmid": "" }, { "name": "regulation of heterochromatin formation", "id": "GO:0031445", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031445", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nuclear chromosome", "id": "GO:0000228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ], "pmid": "" }, { "name": "pericentric heterochromatin", "id": "GO:0005721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y8" } ], "pmid": "" }, 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Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027275286.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275286" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3N3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3N3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Brd4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3N3", "locus": {} } ], "crossref": [ { "id": "cd05497", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05497", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05498", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05498", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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This record is derived from a genomic sequence (NW_003613661.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003497780.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497780", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497780" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772422", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5", "locus": {} } ], "crossref": [ { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772422", "url": "https://www.ncbi.nlm.nih.gov/gene/100772422", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040514", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040514", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772422", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772422", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G3Q5", "url": "https://www.orthodb.org/?gene=A0A9J7G3Q5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19325:SF551", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19325:SF551", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18453", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18453", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497780", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497780", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSAWSCLELWKTSHSTLFQMTLATVLMAPVLGDCGPPPSLPFASPINQLFETTFSSGTVLKYTCHHGFKKVNSSHLTCDENGSWVYNVFCAKKRCRNPGELVNGKVEIMTDLFLGSTIEFSCAKGYLLIGSTTSRCEVQGKGVDWSDSLPECVIVTCESPPDISNGRHSGRDEDLYTYGSSVTYSCDPSFTLLGNASIVCTVVNKTVGVWSPSPPACEKTVCHHPXIAKGELIPGFTQFYSYKHSVEVRCMKGYVLRGSSLIRCEANREWYSSIPTCVPNGCIDLPDIPYAFWEGNKIPLRNFEVFEIGTKLKYQCKPGYRPASNEPQIVRCQENLTWSPSKGCERICCPVPNMEKIKIVSERRDFTGVCIYAYGDYVFYICGEGTYPMSTDGRSSCLADGKWDPAIPACRSDSEIQNRLALITPPSFAETMTKSNKYLSDTEERTRFTSYKSLCSKPVIIHGKLSVDKDHYAEMENITVQCDPGYGLVGSPNIICSEKKTWYPEIPNCKMELPEDCKFVVEGRKLLQCLSIPEEVKKAMEIYKLSLEIERLEQEKERWLRFHRKPSKRVKMKGPFRPFG", "length": 581, "header": "tr|A0A9J7G3Q5-1|A0A9J7G3Q5_CRIGR Isoform 1 of Zona pellucida sperm-binding protein 3 receptor OS=Cricetulus griseus OX=10029 GN=LOC100772422 PE=4 SV=1 CANONICAL=A0A9J7G3Q5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G3Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5/entry#A0A9J7G3Q5-1", "sequence": { "sequence": "MMSAWSCLELWKTSHSTLFQMTLATVLMAPVLGDCGPPPSLPFASPINQLFETTFSSGTVLKYTCHHGFKKVNSSHLTCDENGSWVYNVFCAKKRCRNPGELVNGKVEIMTDLFLGSTIEFSCAKGYLLIGSTTSRCEVQGKGVDWSDSLPECVIVTCESPPDISNGRHSGRDEDLYTYGSSVTYSCDPSFTLLGNASIVCTVVNKTVGVWSPSPPACEKTVCHHPXIAKGELIPGFTQFYSYKHSVEVRCMKGYVLRGSSLIRCEANREWYSSIPTCVPNGCIDLPDIPYAFWEGNKIPLRNFEVFEIGTKLKYQCKPGYRPASNEPQIVRCQENLTWSPSKGCERICCPVPNMEKIKIVSERRDFTGVCIYAYGDYVFYICGEGTYPMSTDGRSSCLADGKWDPAIPACRSDSEIQNRLALITPPSFAETMTKSNKYLSDTEERTRFTSYKSLCSKPVIIHGKLSVDKDHYAEMENITVQCDPGYGLVGSPNIICSEKKTWYPEIPNCKMELPEDCKFVVEGRKLLQCLSIPEEVKKAMEIYKLSLEIERLEQEKERWLRFHRKPSKRVKMKGPFRPFG", "length": 581, "header": "tr|A0A9J7G3Q5-1|A0A9J7G3Q5_CRIGR Isoform 1 of Zona pellucida sperm-binding protein 3 receptor OS=Cricetulus griseus OX=10029 GN=LOC100772422 PE=4 SV=1 CANONICAL=A0A9J7G3Q5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772422", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772422", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5" } ], "pmid": "" }, { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5" } ], "pmid": "" }, { "name": "complement activation, classical pathway", "id": "GO:0006958", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "acrosomal matrix", "id": "GO:0043159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043159", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5" } ], "pmid": "" }, { "name": "acrosomal lumen", "id": "GO:0043160", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043160", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G3Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Q5" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 93, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G866-1", "uniprot_ac": "A0A9J7G866", "uniprot_id": "A0A9J7G866_CRIGR", "mass": { "chemical_mass": 64482.0, "monoisotopic_mass": 64482.0 }, "refseq": { "ac": "XP_016832616", "name": "spermatogenesis-associated protein 7 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832616" }, "gene_names": [ { "name": "LOC100751616", "type": "recommended", "evidence": [ { "id": "A0A9J7G866", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866" } ] }, { "name": "LOC100751616", "type": "synonym", "evidence": [ { "id": "XP_016832616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832616" } ] } ], "protein_names": [ { "name": "Spermatogenesis-associated protein 7 isoform X8", "type": "synonym", "evidence": [ { "id": "A0A9J7G866", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866/entry#names_and_taxonomy" } ] }, { "name": "spermatogenesis-associated protein 7 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_016832616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832616" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 987 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613607.1) and transcript sequence (JI893411.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016832616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832616" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G866", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100751616", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866", "locus": {} } ], "crossref": [ { "id": "A0A9J7G866", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G866", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751616", "url": "https://www.ncbi.nlm.nih.gov/gene/100751616", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G3R1", "url": "https://www.orthodb.org/?gene=A0A9J7G3R1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G866", "url": "https://www.orthodb.org/?gene=A0A9J7G866", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JKD2", "url": "https://www.orthodb.org/?gene=A0A9J7JKD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JTM9", "url": "https://www.orthodb.org/?gene=A0A9J7JTM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14917", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14917", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14917:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14917:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15244", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15244", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016832616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832616", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G3R1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G866", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G866-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1M6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1M6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2A6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9L9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9L9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGSRRAFCTDSSSLRLTTLQLVKNHMTVHYNKILSAKATVDCSIPVSVSTSIKYADQQRREKLKKELARCEKEYKLNKSIMQNNSKMNSKPLFNSLQKPSGEPQGQDVLIEEITRYPSFSKSFVPSSNGLHLSQPESNKMLMNGTQKHLSTSPSSMVCTGSATRSPCPGHGCDGKPRSAFPGAHRFQLVISKTPSGDLLEKHSDLFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFPGQRMEAETQTELSSFNSEFGTAETRNSKDSEVNTKQAPNYMINGAEDKISPLPLEGQTLGWDKIKDGALQQSSKRTLCELSTQLSSDSKIYPDEEELLYLNFMENVTDEILKLGLFSNRFLERLFERHIKQNKHHLEEGKMRYLLHGLKVDLGCISEEQPEKQNSFRMLNQLDFQKALISKHTELVSNDDTLIQQERQQFQEALDMLSSMPKDEDKMFSLPGEFLIPVHRFKYSGVTVQQVNDETDLEASTWNENNPRISDSLIDQETSVDVIEGDSDYEKVETSRELCCLNTSLSPSVQFPSVKNGSNHDKELTLKIMEMSIED", "length": 568, "header": "tr|A0A9J7G866-1|A0A9J7G866_CRIGR Isoform 1 of Spermatogenesis-associated protein 7 isoform X8 OS=Cricetulus griseus OX=10029 GN=LOC100751616 PE=4 SV=1 CANONICAL=A0A9J7G866-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G3R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866/entry#A0A9J7G3R1-1", "sequence": { "sequence": "MTVHYNKILSAKATVDCSIPVSVSTSIKYADQQRREKLKKELARCEKEYKLNKSIMQNNSKMNSKPLFNSLQKPSGEPQGQDVLIEEITRYPSFSKSFVPSSNGLHLSQPESNKMLMNGTQKHLSTSPSSMVCTGSATRSPCPGHGCDGKPRSAFPGAHRFQLVISKTPSGDLLEKHSDLFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFPGQRMEAETQTELSSFNSEFGTAETRNSKDSEVNTKQAPNYMINGAEDKISPLPLEGQTLGWDKIKDGALQQSSKRTLCELSTQLSSDSKIYPDEEELLYLNFMENVTDEILKLGLFSNRFLERLFERHIKQNKHHLEEGKMRYLLHGLKVDLGCISEEQPEKQNSFRMLNQLDFQKALISKHTELVSNDDTLIQQERQQFQEALDMLSSMPKDEDKMFSLPGEFLIPVHRFKYSGVTVQQVNDETDLEASTWNENNPRISDSLIDQETSVDVIEGDSDYEKVETSRELCCLNTSLSPSVQFPSVKNGSNHDKELTLKIMEMSIED", "length": 542, "header": "tr|A0A9J7G3R1-1|A0A9J7G866_CRIGR Computationally mapped isoform of Spermatogenesis-associated protein 7 isoform X8 OS=Cricetulus griseus OX=10029 GN=LOC100751616 PE=4 SV=1 CANONICAL=A0A9J7G866-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G866-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866/entry#A0A9J7G866-1", "sequence": { "sequence": "MDGSRRAFCTDSSSLRLTTLQLVKNHMTVHYNKILSAKATVDCSIPVSVSTSIKYADQQRREKLKKELARCEKEYKLNKSIMQNNSKMNSKPLFNSLQKPSGEPQGQDVLIEEITRYPSFSKSFVPSSNGLHLSQPESNKMLMNGTQKHLSTSPSSMVCTGSATRSPCPGHGCDGKPRSAFPGAHRFQLVISKTPSGDLLEKHSDLFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFPGQRMEAETQTELSSFNSEFGTAETRNSKDSEVNTKQAPNYMINGAEDKISPLPLEGQTLGWDKIKDGALQQSSKRTLCELSTQLSSDSKIYPDEEELLYLNFMENVTDEILKLGLFSNRFLERLFERHIKQNKHHLEEGKMRYLLHGLKVDLGCISEEQPEKQNSFRMLNQLDFQKALISKHTELVSNDDTLIQQERQQFQEALDMLSSMPKDEDKMFSLPGEFLIPVHRFKYSGVTVQQVNDETDLEASTWNENNPRISDSLIDQETSVDVIEGDSDYEKVETSRELCCLNTSLSPSVQFPSVKNGSNHDKELTLKIMEMSIED", "length": 568, "header": "tr|A0A9J7G866-1|A0A9J7G866_CRIGR Isoform 1 of Spermatogenesis-associated protein 7 isoform X8 OS=Cricetulus griseus OX=10029 GN=LOC100751616 PE=4 SV=1 CANONICAL=A0A9J7G866-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866/entry#A0A9J7H1M6-1", "sequence": { "sequence": "MQNNSKMNSKPLFNSLQKPSGEPQGQDVLIEEITRYPSFSKSFVPSSNGLHLSQPESNKMLMNGTQKHLSTSPSSMVCTGSATRSPCPGHGCDGKPRSAFPGAHRFQLVISKTPSGDLLEKHSDLFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFPGQRMEAETQTELSSFNSEFGTAETRNSKDSEVNTKQAPNYMINGAEDKISPLPLEGQTLGWDKIKDGALQQSSKRTLCELSTQLSSDSKIYPDEEELLYLNFMENVTDEILKLGLFSNRFLERLFERHIKQNKHHLEEGKMRYLLHGLKVDLGCISEEQPEKQNSFRMLNQLDFQKALISKHTELVSNDDTLIQQERQQFQEALDMLSSMPKDEDKMFSLPGEFLIPVHRFKYSGVTVQQVNDETDLEASTWNENNPRISDSLIDQETSVDVIEGDSDYEKVETSRELCCLNTSLSPSVQFPSVKNGSNHDKELTLKIMEMSIED", "length": 487, "header": "tr|A0A9J7H1M6-1|A0A9J7H1M6_CRIGR Computationally mapped isoform of Spermatogenesis-associated protein 7 isoform X14 OS=Cricetulus griseus OX=10029 GN=LOC100751616 PE=4 SV=1 CANONICAL=A0A9J7G866-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866/entry#A0A9J7H2A6-1", "sequence": { "sequence": "MDGSRRVRATSVLPRYNPPCLFTGHLSTKSNAFCTDSSSLRLTTLQLVKNHMTVHYNKILSAKATVDCSIPVSVSTSIKYADQQRREKLKKELARCEKEYKLNKSIMQNNSKMNSKPLFNSLQKPSGEPQGQDVLIEEITRYPSFSKSFVPSSNGLHLSQPESNKMLMNGTQKHLSTSPSSMVCTGSATRSPCPGHGCDGKPRSAFPGAHRFQLVISKTPSGDLLEKHSDLFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFPGQRMEAETQTELSSFNSEFGTAETRNSKDSEVNTKQAPNYMINGAEDKISPLPLEGQTLGWDKIKDGALQQSSKRTLCELSTQLSSDSKIYPEFLERLFERHIKQNKHHLEEGKMRYLLHGLKVDLGCISEEQPEKQNSFRMLNQLDFQKALISKHTELVSNDDTLIQQERQQFQEALDMLSSMPKDEDKMFSLPGEFLIPVHRFKYSGVTVQQVNDETDLEASTWNENNPRISDSLIDQETSVDVIEGDSDYEKVETSRELCCLNTSLSPSVQFPSVKNGSNHDKELTLKIMEMSIED", "length": 567, "header": "tr|A0A9J7H2A6-1|A0A9J7H2A6_CRIGR Computationally mapped isoform of Spermatogenesis-associated protein 7 isoform X9 OS=Cricetulus griseus OX=10029 GN=LOC100751616 PE=4 SV=1 CANONICAL=A0A9J7G866-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866/entry#A0A9J7JKD2-1", "sequence": { "sequence": "MDGSRRATVDCSIPVSVSTSIKYADQQRREKLKKELARCEKEYKLNKSIMQNNSKMNSKPLFNSLQKPSGEPQGQDVLIEEITRYPSFSKSFVPSSNGLHLSQPESNKMLMNGTQKHLSTSPSSMVCTGSATRSPCPGHGCDGKPRSAFPGAHRFQLVISKTPSGDLLEKHSDLFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFPGQRMEAETQTELSSFNSEFGTAETRNSKDSEVNTKQAPNYMINGAEDKISPLPLEGQTLGWDKIKDGALQQSSKRTLCELSTQLSSDSKIYPDEEELLYLNFMENVTDEILKLGLFSNRFLERLFERHIKQNKHHLEEGKMRYLLHGLKVDLGCISEEQPEKQNSFRMLNQLDFQKALISKHTELVSNDDTLIQQERQQFQEALDMLSSMPKDEDKMFSLPGEFLIPVHRFKYSGVTVQQVNDETDLEASTWNENNPRISDSLIDQETSVDVIEGDSDYEKVETSRELCCLNTSLSPSVQFPSVKNGSNHDKELTLKIMEMSIED", "length": 536, "header": "tr|A0A9J7JKD2-1|A0A9J7JKD2_CRIGR Computationally mapped isoform of Spermatogenesis-associated protein 7 isoform X12 OS=Cricetulus griseus OX=10029 GN=LOC100751616 PE=4 SV=1 CANONICAL=A0A9J7G866-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866/entry#A0A9J7JTM9-1", "sequence": { "sequence": "MTYADQQRREKLKKELARCEKEYKLNKSIMQNNSKMNSKPLFNSLQKPSGEPQGQDVLIEEITRYPSFSKSFVPSSNGLHLSQPESNKMLMNGTQKHLSTSPSSMVCTGSATRSPCPGHGCDGKPRSAFPGAHRFQLVISKTPSGDLLEKHSDLFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFPGQRMEAETQTELSSFNSEFGTAETRNSKDSEVNTKQAPNYMINGAEDKISPLPLEGQTLGWDKIKDGALQQSSKRTLCELSTQLSSDSKIYPDEEELLYLNFMENVTDEILKLGLFSNRFLERLFERHIKQNKHHLEEGKMRYLLHGLKVDLGCISEEQPEKQNSFRMLNQLDFQKALISKHTELVSNDDTLIQQERQQFQEALDMLSSMPKDEDKMFSLPGEFLIPVHRFKYSGVTVQQVNDETDLEASTWNENNPRISDSLIDQETSVDVIEGDSDYEKVETSRELCCLNTSLSPSVQFPSVKNGSNHDKELTLKIMEMSIED", "length": 516, "header": "tr|A0A9J7JTM9-1|A0A9J7JTM9_CRIGR Computationally mapped isoform of Spermatogenesis-associated protein 7 isoform X13 OS=Cricetulus griseus OX=10029 GN=LOC100751616 PE=4 SV=1 CANONICAL=A0A9J7G866-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866/entry#A0A9J7K9L9-1", "sequence": { "sequence": "MDGSRRVRATSVLPRYNPPCLFTGHLSTKSNATVDCSIPVSVSTSIKYADQQRREKLKKELARCEKEYKLNKSIMQNNSKMNSKPLFNSLQKPSGEPQGQDVLIEEITRYPSFSKSFVPSSNGLHLSQPESNKMLMNGTQKHLSTSPSSMVCTGSATRSPCPGHGCDGKPRSAFPGAHRFQLVISKTPSGDLLEKHSDLFSNKQLPFTPRTLKTEAKSFLSQYRYYTPAKRRKDFPGQRMEAETQTELSSFNSEFGTAETRNSKDSEVNTKQAPNYMINGAEDKISPLPLEGQTLGWDKIKDGALQQSSKRTLCELSTQLSSDSKIYPDEEELLYLNFMENVTDEILKLGLFSNRFLERLFERHIKQNKHHLEEGKMRYLLHGLKVDLGCISEEQPEKQNSFRMLNQLDFQKALISKHTELVSNDDTLIQQERQQFQEALDMLSSMPKDEDKMFSLPGEFLIPVHRFKYSGVTVQQVNDETDLEASTWNENNPRISDSLIDQETSVDVIEGDSDYEKVETSRELCCLNTSLSPSVQFPSVKNGSNHDKELTLKIMEMSIED", "length": 561, "header": "tr|A0A9J7K9L9-1|A0A9J7K9L9_CRIGR Computationally mapped isoform of Spermatogenesis-associated protein 7 isoform X10 OS=Cricetulus griseus OX=10029 GN=LOC100751616 PE=4 SV=1 CANONICAL=A0A9J7G866-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 234, "start_aa": "Thr", "end_pos": 234, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr234", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3R1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3R1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3R1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3R1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "photoreceptor cell maintenance", "id": "GO:0045494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045494", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G866", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G866", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G866", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G866", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866" } ], "pmid": "" }, { "name": "photoreceptor distal connecting cilium", "id": "GO:0120206", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120206", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G866", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866" } ], "pmid": "" }, { "name": "rod photoreceptor outer segment", "id": "GO:0120200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120200", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G866", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G866" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 549, "end_pos": 551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 234 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 549, "end_pos": 551 }, { "start_pos": 78, "end_pos": 80 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G3R9-1", "uniprot_ac": "A0A9J7G3R9", "uniprot_id": "A0A9J7G3R9_CRIGR", "mass": { "chemical_mass": 94269.0, "monoisotopic_mass": 94269.0 }, "refseq": { "ac": "XP_027275355", "name": "LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275355" }, "gene_names": [ { "name": "Hcn2", "type": "recommended", "evidence": [ { "id": "A0A9J7G3R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3R9" } ] }, { "name": "Hcn2", "type": "synonym", "evidence": [ { "id": "XP_027275355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275355" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027275355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275355" }, { "id": "A0A9J7G3R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3R9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 5 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 434 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616113.1) and transcript sequence (JP055598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016818740", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818740" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prorp", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S6", "locus": {} } ], "crossref": [ { "id": "cd18718", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18718", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757198", "url": "https://www.ncbi.nlm.nih.gov/gene/100757198", "database": "GeneID", "categories": [ "Genome 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"MTYLLGFRNIQKLWRSTPCFELGLATSPVSLFLGVTRNQHRWLCVKTTFPLNSKAINLLVAKTRTLKEENDSSRQVSSDHYFAAGAAKKRAHLNNNLQQRDHAVSRKRGTIEVPTTPLNSEEWDQLKEDFKGKISFEDKVISQMVRNRSSVDVAKSLLAWVAAKNNGIVGYNLLVKYLYLCVYHKETSEVIDVYEIMKAKYKCLETGANSILIRGLIHSDRWREALLRLEEIKKVTIPSKKNYNDCIQGALFHQDVNLAWSLYQELIDHNLIPLLDTLKAFFDFGKHINDDHYSNKLLDILLYLRNNQMFPGESLAHSIKTWFESIPGRQWKGQFTTVQKSGQCSGCGRVLESIHLSPEEYEFLKEKIMRHVIDGGDQYKKTTPQELKRFEKFVNSCPPFDIVIDGLNVAKMVFKNRESQTLLDVVSQLAQQNLRLLVLGRKHMLTPSSQWKKDEMKQVQEQADCFFADNI", "length": 471, "header": "tr|A0A9J7G760-1|A0A9J7G760_CRIGR Computationally mapped isoform of ribonuclease P OS=Cricetulus griseus OX=10029 GN=Prorp PE=3 SV=1 CANONICAL=A0A9J7G3S6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JU11-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S6/entry#A0A9J7JU11-1", "sequence": { "sequence": "MVTCKHAWRGELVNAVSFVCRSSEHIPGRQWKGQFTTVQKSGQCSGCGRVLESIHLSPEEYEFLKEKIMRHVIDGGDQYKKTTPQELKRFEKFVNSCPPFDIVIDGLNVAKMVFKNRESQTLLDVVSQLAQQNLRLLVLGRKHMLTPSSQWKKDEMKQVQEQADCFFADNISKDDPFLLYATLNSGNHCKFITKDLMRDHKACLPDAHTRHLFFKWQQGHQLTIMNCLQRSKLAFQHTFSYDTVVQTTGDSWHIPYDEDQVQRSSYEVPTKWLCLQRKTKTSAPC", "length": 285, "header": "tr|A0A9J7JU11-1|A0A9J7JU11_CRIGR Computationally mapped isoform of Mitochondrial ribonuclease P catalytic subunit isoform X6 OS=Cricetulus griseus OX=10029 GN=Prorp PE=3 SV=1 CANONICAL=A0A9J7G3S6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757198", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757198", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S6" } ], "pmid": "" }, { "name": "mitochondrial ribonuclease P complex", "id": "GO:0030678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030678", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S6" } ], "pmid": "" }, { "name": "ribonuclease P activity", "id": "GO:0004526", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004526", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "tRNA 5'-leader removal", "id": "GO:0001682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S6" } ], "pmid": "" }, { "name": "mitochondrial tRNA 5'-end processing", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G3U4-1", "uniprot_ac": "A0A9J7G3U4", "uniprot_id": "A0A9J7G3U4_CRIGR", "mass": { "chemical_mass": 222988.0, "monoisotopic_mass": 222988.0 }, "refseq": { "ac": "XP_027275414", "name": "echinoderm microtubule-associated protein-like 5 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275414" }, "gene_names": [ { "name": "Eml5", "type": "recommended", "evidence": [ { "id": "A0A9J7G3U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4" } ] }, { "name": "Eml5", "type": "synonym", "evidence": [ { "id": "XP_027275414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275414" } ] } ], "protein_names": [ { "name": "Echinoderm microtubule-associated protein-like 5 isoform X5", "type": "synonym", "evidence": [ { "id": "A0A9J7G3U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4/entry#names_and_taxonomy" } ] }, { "name": "echinoderm microtubule-associated protein-like 5 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_027275414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275414" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275414" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Eml5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4", "locus": {} } ], "crossref": [ { "id": "100771482", "url": "https://www.ncbi.nlm.nih.gov/gene/100771482", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771482", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771482", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G3U4", "url": "https://www.orthodb.org/?gene=A0A9J7G3U4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03451", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03451", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275414", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G3U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKD6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTN5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHTAGIFSMNACEEGFATGGRDGCIRLWDLAFKPITVIDLRETDQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNVDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECVGSLSFITHMDWSSDSRYLQTNDGSGKRLLYRMPGGKEVTSKEETKGVHWASWTCVSGLEVNGIWPKYSDVNDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLAESNSDESDSDLSDVPELDSEIEQETQLTYHRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFIHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHIWDTETIKPLSILKGYHQYGVCAVDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGRKGYIGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLVKTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDRTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIQFSPGSGKYLAVASHDSFIDIYNVMSSKRVGICKGATSYITHIDWDARGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKISWASWTSVLGLCCEGIWPIIGEVTDVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTNEMESCREKKSCDSEESDIDSEEDGGYDSDVTRENEISYTIRALSTNIRPMLGVKPHLQQKEPSVDERPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFGYRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSPDMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTITIWRWQEGARIASRAGHNQRIFVAEFRPDSDTQFVSVGIKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAVAFGANNLTFTGTISGDVCVWKDHMLCRVVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCVRSVCRGKGKILVGTRNAEIIEVGEKNAACNVLVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHIVSAGGDDCRSVVSQCRKSTATLCKDSVTPLYSFSNQHSQHSSDGTITSDSKVIHLI", "length": 2005, "header": "tr|A0A9J7G3U4-1|A0A9J7G3U4_CRIGR Isoform 1 of Echinoderm microtubule-associated protein-like 5 isoform X5 OS=Cricetulus griseus OX=10029 GN=Eml5 PE=3 SV=1 CANONICAL=A0A9J7G3U4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G3U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4/entry#A0A9J7G3U4-1", "sequence": { "sequence": "MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHTAGIFSMNACEEGFATGGRDGCIRLWDLAFKPITVIDLRETDQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNVDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECVGSLSFITHMDWSSDSRYLQTNDGSGKRLLYRMPGGKEVTSKEETKGVHWASWTCVSGLEVNGIWPKYSDVNDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLAESNSDESDSDLSDVPELDSEIEQETQLTYHRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFIHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHIWDTETIKPLSILKGYHQYGVCAVDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGRKGYIGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLVKTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDRTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIQFSPGSGKYLAVASHDSFIDIYNVMSSKRVGICKGATSYITHIDWDARGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKISWASWTSVLGLCCEGIWPIIGEVTDVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTNEMESCREKKSCDSEESDIDSEEDGGYDSDVTRENEISYTIRALSTNIRPMLGVKPHLQQKEPSVDERPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFGYRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSPDMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTITIWRWQEGARIASRAGHNQRIFVAEFRPDSDTQFVSVGIKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAVAFGANNLTFTGTISGDVCVWKDHMLCRVVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCVRSVCRGKGKILVGTRNAEIIEVGEKNAACNVLVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHIVSAGGDDCRSVVSQCRKSTATLCKDSVTPLYSFSNQHSQHSSDGTITSDSKVIHLI", "length": 2005, "header": "tr|A0A9J7G3U4-1|A0A9J7G3U4_CRIGR Isoform 1 of Echinoderm microtubule-associated protein-like 5 isoform X5 OS=Cricetulus griseus OX=10029 GN=Eml5 PE=3 SV=1 CANONICAL=A0A9J7G3U4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4/entry#A0A9J7JKD6-1", "sequence": { "sequence": "MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHTAGIFSMNACEEGFATGGRDGCIRLWDLAFKPITVIDLRETDQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNVDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECVGSLSFITHMDWSSDSRYLQTNDGSGKRLLYRMPGGKEVTSKEETKGVHWASWTCVSGLEVNGIWPKYSDVNDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLAESNSDESDSDLSDVPELDSEIEQETQLTYHRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFIHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHIWDTETIKPLSILKGYHQYGVCAVDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGRKGYIGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLVKTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDRTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIQFSPGSGKYLAVASHDSFIDIYNVMSSKRVGICKGATSYITHIDWDARGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKISWASWTSVLGLCCEGIWPIIGEVTDVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTNEMESCREKKSCDSEESDIDSEEDGGYDSDVTRENEISYTIRALSTNIRPMLGVKPHLQQKEPSVDERQGVVRPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFGYRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSPDMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTITIWRWQEGARIASRAGHNQRIFVAEFRPDSDTQFVSVGIKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAVAFGANNLTFTGTISGDVCVWKDHMLCRVVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCVRSVCRGKGKILVGTRNAEIIEVGEKNAACNVLVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHIVSAGGDDCSLFVWKCVYMPH", "length": 1974, "header": "tr|A0A9J7JKD6-1|A0A9J7JKD6_CRIGR Computationally mapped isoform of Echinoderm microtubule-associated protein-like 5 isoform X6 OS=Cricetulus griseus OX=10029 GN=Eml5 PE=3 SV=1 CANONICAL=A0A9J7G3U4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4/entry#A0A9J7JSC9-1", "sequence": { "sequence": "MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHTAGIFSMNACEEGFATGGRDGCIRLWDLAFKPITVIDLRETDQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNVDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECVGSLSFITHMDWSSDSRYLQTNDGSGKRLLYRMPGGKEVTSKEETKGVHWASWTCVSGLEVNGIWPKYSDVNDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLAESNSDESDSDLSDVPELDSEIEQETQLTYHRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFIHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHIWDTETIKPLSILKGYHQYGVCAVDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGRKGYIGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLVKTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDRTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIQFSPGSGKYLAVASHDSFIDIYNVMSSKRVGICKGATSYITHIDWDARGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKISWASWTSVLGLCCEGIWPIIGEVTDVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTNEMESCREKKSCDSEESDIDSEEDGGYDSDVTRENEISYTIRALSTNIRPMLGVKPHLQQKEPSVDERQGVVRPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFGYRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSPDMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTITIWRWQEGARIASRAGHNQRIFVAEFRPDSDTQFVSVGIKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAVAFGAVPSVVMSVCGKITCCVEWWLERTMGLCLPCIPPCEMDSS", "length": 1616, "header": "tr|A0A9J7JSC9-1|A0A9J7JSC9_CRIGR Computationally mapped isoform of Echinoderm microtubule-associated protein-like 5 isoform X8 OS=Cricetulus griseus OX=10029 GN=Eml5 PE=3 SV=1 CANONICAL=A0A9J7G3U4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4/entry#A0A9J7JTN5-1", "sequence": { "sequence": "MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGRMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHTAGIFSMNACEEGFATGGRDGCIRLWDLAFKPITVIDLRETDQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMEEPIRCAAVNVDGIHLALGMKDGSFTVLRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECVGSLSFITHMDWSSDSRYLQTNDGSGKRLLYRMPGGKEVTSKEETKGVHWASWTCVSGLEVNGIWPKYSDVNDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLAESNSDESDSDLSDVPELDSEIEQETQLTYHRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFIHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHIWDTETIKPLSILKGYHQYGVCAVDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVTRGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGRKGYIGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLVKTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPITLLVQGHMEGEVWGLATHPYLPICATVSDDRTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDIISDIQFSPGSGKYLAVASHDSFIDIYNVMSSKRVGICKGATSYITHIDWDARGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKISWASWTSVLGLCCEGIWPIIGEVTDVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTNEMESCREKKSCDSEESDIDSEEDGGYDSDVTRENEISYTIRALSTNIRPMLGVKPHLQQKEPSVDERPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFGYRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSPDMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTITIWRWQEGARIASRAGHNQRIFVAEFRPDSDTQFVSVGIKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAVAFGANNLTFTGTISGDVCVWKDHMLCRVVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCVRSVCRGKGKILVGTRNAEIIEVGEKNAACNVLVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHIVSAGGDDCSLFVWKCVYMPH", "length": 1969, "header": "tr|A0A9J7JTN5-1|A0A9J7JTN5_CRIGR Computationally mapped isoform of Echinoderm microtubule-associated protein-like 5 isoform X7 OS=Cricetulus griseus OX=10029 GN=Eml5 PE=3 SV=1 CANONICAL=A0A9J7G3U4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771482", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771482", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3U4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1574, "end_pos": 1576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 863, "end_pos": 865, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G3U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4" }, { "id": "PF23409", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like first beta-propeller", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 307, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G3U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3U4" }, { "id": "PF23414", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23414" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EML-like second beta-propeller", "eco_id": "ECO_0000259", "start_pos": 328, "end_pos": 592, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1574, "end_pos": 1576 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 863, "end_pos": 865 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G3V7-1", "uniprot_ac": "A0A9J7G3V7", "uniprot_id": "A0A9J7G3V7_CRIGR", "mass": { "chemical_mass": 125834.0, "monoisotopic_mass": 125834.0 }, "refseq": { "ac": "XP_027275431", "name": "basic proline-rich protein-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275431" }, "gene_names": [ { "name": "LOC100768287", "type": "recommended", "evidence": [ { "id": "A0A9J7G3V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3V7" } ] }, { "name": "LOC100768287", "type": "synonym", "evidence": [ { "id": "XP_027275431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275431" } ] } ], "protein_names": [ { "name": "Basic proline-rich protein-like isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7G3V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3V7/entry#names_and_taxonomy" } ] }, { "name": "basic proline-rich protein-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027275431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275431" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027275431.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275431" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G3V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3V7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100768287", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3V7", "locus": {} } ], "crossref": [ { "id": "A0A9J7G3V7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G3V7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768287", "url": "https://www.ncbi.nlm.nih.gov/gene/100768287", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768287", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768287", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G3V7", "url": "https://www.orthodb.org/?gene=A0A9J7G3V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23158:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23158:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_027275431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275431", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G3V7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3V7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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"protein_names": [ { "name": "Cytohesin-2", "type": "recommended", "evidence": [ { "id": "A0A9J7G3Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y3/entry#names_and_taxonomy" } ] }, { "name": "PH, SEC7 and coiled-coil domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A9J7G3Y3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3Y3/entry#names_and_taxonomy" } ] }, { "name": "cytohesin-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027276382", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276382" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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hybrid assembly strategy.", "journal": "Biotechnol. 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"cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 675 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 477, "end_pos": 479 }, { "start_pos": 545, "end_pos": 547 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", 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{ "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G4X6-1", "uniprot_ac": "A0A9J7G4X6", "uniprot_id": "A0A9J7G4X6_CRIGR", "mass": { "chemical_mass": 85248.0, "monoisotopic_mass": 85248.0 }, "refseq": { "ac": "XP_016835378", "name": "mediator of RNA polymerase II transcription subunit 25 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835378" }, "gene_names": [ { "name": "Med25", "type": "recommended", "evidence": [ { "id": "A0A9J7G4X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6" } ] }, { "name": "Med25", "type": "synonym", "evidence": [ { "id": "XP_016835378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835378" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 25", "type": "recommended", "evidence": [ { "id": "A0A9J7G4X6", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NW_003614984.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016835378.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016835378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835378" } ] }, { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G749", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G749#function" }, { "database": "UniProtKB", "id": "RU369088", "url": "https://www.uniprot.org/uniprotkb/RU369088#function" }, { "database": "UniProtKB", "id": "A0A9J7G8I0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I0#function" }, { "database": "UniProtKB", "id": "A0A9J7G440", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G440#function" }, { "database": "UniProtKB", "id": "A0A9J7G4X2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X2#function" }, { "database": "UniProtKB", "id": "A0A9J7G4X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6#function" }, { "database": "UniProtKB", "id": "A0A8C2MWP8", "url": 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"Enzyme and Pathway" ] }, { "id": "NDQQKIP", "url": "https://omabrowser.org/oma/group/NDQQKIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MWP8", "url": "https://www.orthodb.org/?gene=A0A8C2MWP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G440", "url": "https://www.orthodb.org/?gene=A0A9J7G440", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G4X2", "url": "https://www.orthodb.org/?gene=A0A9J7G4X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G4X6", "url": "https://www.orthodb.org/?gene=A0A9J7G4X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G8I0", "url": "https://www.orthodb.org/?gene=A0A9J7G8I0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12433", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12433", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12433:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12433:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11265", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11265", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18658", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18658", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016835378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835378", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MWP8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MWP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G440", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G440", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G440-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G440-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4X2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4X6-1", "url": 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"MVPGSEGPARAGGLVADVVFVIEGTANLGPYFDELRDHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLNGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPVDVSQDPRHMVLVRGLVLPVGGSSVPGPLQPKQPVPLPPTPSSAAPQQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLAPGPPGAPKPPPASQPSLVSTVAPGTGLAPTAQPGAPSMQAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQALPGLGPILEDQARPPQNLLQLRAPQPQPQGAVGASVATGQPQPQGTTQAPTGAPQGPPGTAPGPPPSGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQSLGQPQLGPQLLHPPPAQSWPTQLPQRAPLPVAKRKKEGEGRVFREKWERDYFFVEVKNMPTCLICKKNVSVLKEYNLKRHYESQHSKSYDQYTAQHRDVVLQELKRALRASEALENPE", "length": 798, "header": "tr|A0A9J7G4X6-1|A0A9J7G4X6_CRIGR Isoform 1 of Mediator of RNA polymerase II transcription subunit 25 OS=Cricetulus griseus OX=10029 GN=Med25 PE=3 SV=1 CANONICAL=A0A9J7G4X6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MWP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6/entry#A0A8C2MWP8-1", "sequence": { "sequence": "MVPGSEGPARAGGLVADVVFVIEGTANLGPYFDELRDHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLNGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPVDVSQDPRHMVLVRGLVLPVGGSSVPGPLQPKQPVPLPPTPSSAAPQQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLAPGPPGAPKPPPASQPSLVSTVAPGTGLAPTAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQALPGLGPILEDQARPPQNLLQLRAPQPQPQGAVGASVATGQPQPQGTTQAPTGAPQGPPGTAPGPPPSGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQSLGQPQLGPQLLHPPPAQSWPTQLPQRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI", "length": 741, "header": "tr|A0A8C2MWP8-1|A0A8C2MWP8_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 25 OS=Cricetulus griseus OX=10029 GN=Med25 PE=3 SV=1 CANONICAL=A0A9J7G4X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G440-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6/entry#A0A9J7G440-1", "sequence": { "sequence": "MVPGSEGPARAGGLVADVVFVIEGTANLGPYFDELRDHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLNGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPVDVSQDPRHMVLVRGLVLPVGGSSVPGPLQPKQPVPLPPTPSSAAPQQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLAPGPPGAPKPPPASQPSLVSTVAPGTGLAPTAQPGAPSMQAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGLQLRAPQPQPQGAVGASVATGQPQPQGTTQAPTGAPQGPPGTAPGPPPSGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQSLGQPQLGPQLLHPPPAQSWPTQLPQRAPLPVAKRKKEGEGRVFREKWERDYFFVEVKNMPTCLICKKNVSVLKEYNLKRHYESQHSKSYDQYTAQHRDVVLQELKRALRASEALENPE", "length": 774, "header": "tr|A0A9J7G440-1|A0A9J7G4X6_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 25 OS=Cricetulus griseus OX=10029 GN=Med25 PE=3 SV=1 CANONICAL=A0A9J7G4X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6/entry#A0A9J7G4X2-1", "sequence": { "sequence": "MVPGSEGPARAGGLVADVVFVIEGTANLGPYFDELRDHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLNGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPVDVSQDPRHMVLVRGLVLPVGGSSVPGPLQPKQPVPLPPTPSSAAPQQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLAPGPPGAPKPPPASQPSLVSTVAPGTGLAPTAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQALPGLGPILEDQARPPQNLLQLRAPQPQPQGAVGASVATGQPQPQGTTQAPTGAPQGPPGTAPGPPPSGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQSLGQPQLGPQLLHPPPAQSWPTQLPQRAPLPVAKRKKEGEGRVFREKWERDYFFVEVKNMPTCLICKKNVSVLKEYNLKRHYESQHSKSYDQYTAQHRDVVLQELKRALRASEALENPE", "length": 797, "header": "tr|A0A9J7G4X2-1|A0A9J7G4X2_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 25 OS=Cricetulus griseus OX=10029 GN=Med25 PE=3 SV=1 CANONICAL=A0A9J7G4X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6/entry#A0A9J7G4X6-1", "sequence": { "sequence": "MVPGSEGPARAGGLVADVVFVIEGTANLGPYFDELRDHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLNGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPVDVSQDPRHMVLVRGLVLPVGGSSVPGPLQPKQPVPLPPTPSSAAPQQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLAPGPPGAPKPPPASQPSLVSTVAPGTGLAPTAQPGAPSMQAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQALPGLGPILEDQARPPQNLLQLRAPQPQPQGAVGASVATGQPQPQGTTQAPTGAPQGPPGTAPGPPPSGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQSLGQPQLGPQLLHPPPAQSWPTQLPQRAPLPVAKRKKEGEGRVFREKWERDYFFVEVKNMPTCLICKKNVSVLKEYNLKRHYESQHSKSYDQYTAQHRDVVLQELKRALRASEALENPE", "length": 798, "header": "tr|A0A9J7G4X6-1|A0A9J7G4X6_CRIGR Isoform 1 of Mediator of RNA polymerase II transcription subunit 25 OS=Cricetulus griseus OX=10029 GN=Med25 PE=3 SV=1 CANONICAL=A0A9J7G4X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G749-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6/entry#A0A9J7G749-1", "sequence": { "sequence": "MVPGSEGPARAGGLVADVVFVIEGTANLGPYFDELRDHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLNGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPVDVSQDPRHMVLVRGLVLPVGGSSVPGPLQPKQPVPLPPTPSSAAPQQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLAPGPPGAPKPPPASQPSLVSTVAPGTGLAPTAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGLQLRAPQPQPQGAVGASVATGQPQPQGTTQAPTGAPQGPPGTAPGPPPSGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQSLGQPQLGPQLLHPPPAQSWPTQLPQRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI", "length": 717, "header": "tr|A0A9J7G749-1|A0A9J7G749_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 25 OS=Cricetulus griseus OX=10029 GN=Med25 PE=3 SV=1 CANONICAL=A0A9J7G4X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6/entry#A0A9J7G8I0-1", "sequence": { "sequence": "MVPGSEGPARAGGLVADVVFVIEGTANLGPYFDELRDHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLNGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPVDVSQDPRHMVLVRGLVLPVGGSSVPGPLQPKQPVPLPPTPSSAAPQQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLAPGPPGAPKPPPASQPSLVSTVAPGTGLAPTAQPGAPSMQAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQALPGLGPILEDQARPPQNLLQLRAPQPQPQGAVGASVATGQPQPQGTTQAPTGAPQGPPGTAPGPPPSGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQSLGQPQLGPQLLHPPPAQSWPTQLPQRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI", "length": 742, "header": "tr|A0A9J7G8I0-1|A0A9J7G8I0_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 25 OS=Cricetulus griseus OX=10029 GN=Med25 PE=3 SV=1 CANONICAL=A0A9J7G4X6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6/entry#A0A9J7H3F7-1", "sequence": { "sequence": "MGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPVDVSQDPRHMVLVRGLVLPVGGSSVPGPLQPKQPVPLPPTPSSAAPQQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLAPGPPGAPKPPPASQPSLVSTVAPGTGLAPTAQPGAPSMQAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQALPGLGPILEDQARPPQNLLQLRAPQPQPQGAVGASVATGQPQPQGTTQAPTGAPQGPPGTAPGPPPSGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQSLGQPQLGPQLLHPPPAQSWPTQLPQRAPLPVAKRKKEGEGRVFREKWERDYFFVEVKNMPTCLICKKNVSVLKEYNLKRHYESQHSKSYDQYTAQHRDVVLQELKRALRASEALENPE", "length": 695, "header": "tr|A0A9J7H3F7-1|A0A9J7H3F7_CRIGR Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 25 OS=Cricetulus griseus OX=10029 GN=Med25 PE=3 SV=1 CANONICAL=A0A9J7G4X6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 250, "start_aa": "Thr", "end_pos": 250, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr250", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G440", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G440" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G440", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G440" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767409", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767409", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6B1T5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 25", "gene_name": "Med25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRQGRDKTTTPKMPRTNMAVSASAEVARRPAGVRAPRKRTSVRPGTATASAALAAAAAARGMVPGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPADVSQDPRHMVLVRGLVLPVGGSSAPGPLQPKQAVPLPPAPTSAATLSAAPQQTLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQAASGVGPPFSQAPAPPLAPGPPGAPKPPPASQPSLVSTVAPGPGLAAPAQPGAPSMQAGTVTPGGVSGPSPAQLGGPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPPQNLLQLRAPQPQPQGAVGASAATGQPQPQGTTQAPTGAPQGPPGAAPGPPPSGPILRPQNPGANPQLRSLLLNPAPPQTGVPPPQASLHHLQPPGAPALLPPHQSLGQPQLGPQLLHPPPTQSWPTQLPQRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI", "length": 807 }, "evidence": [ { "id": "A0A9J7G4X6", "url": "https://omabrowser.org/oma/group/A0A9J7G4X6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2VE44-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 25", "gene_name": "MED25", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVPGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTETLVQKIGERGIYFSIVSPRKLPALRLLFEKAAPPAMLEPLQPPADVSQDPRHMVLVRGLVLPVGGGSAPGPLQPKQPVPLPPAAPAGATLSTAPQQPLPPVPQQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPINPLQQATPGVGPPYSQTQATQLPPGPPGAPKPPPASQPSLVSTVAPGPGLAPPAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLDSLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGTVGASAAAGQPQPQGAAPAPPGAPQGPPGAAPGPPPPGPLLRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRASLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI", "length": 746 }, "evidence": [ { "id": "A0A9J7G4X6", "url": "https://omabrowser.org/oma/group/A0A9J7G4X6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PEH8-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 25", "gene_name": "med25", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDPTSKSGLNQVSDVVFVIEGTANLGPYFESLRNNYILPTIEYFNGGPPAETDFGGDYGGTQYGLVVFNTVDCAPESYVQCHAPTSSAFEFVSWIDSIQFMGGGAESCSLIAEGLSVALQLFDDFKKMREQIGQTHKVCVLLCNSPPYLLPAVESVSYTGCTADSLVQIIRDRGIHFSVIAPRKLPALRSLFERASSVAGLPESSHPDYSQDPFHMVLVRGIALPVAPGGGSVPVSLKPVLPPQSLPVNQNPLVPVASTAPQMNTFQNVSLHAAHDAAQKALEEAANQQQKNRFGQISTPPFSQSPVLPPGGKPSLSTVTTVSPPVLTQQQVPPQQPQQQTQVPQPGLPAVNQQPPQASQQQPNNQQTPPPTQPGMAAVPAPPPGAQQGVANKVVAWSGVLEWQEKPKASSMDSNTKLTRSLPCQVQVSQGENLNTDQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFLFTNKDMESLKGLFRIMTSGFAGCVHFPHSAPCEVRVLMLLYSSRKRIFMGLIPNDQSGFVNGIRQVITNHKQVQQQRSMQPGQVQPNQNFLNRPPGPIPVTHGNVPQQLRAAATGNQQAPVTGAPPNQVQGQAQAPGGGMLRLQNPGANPQLRSLLLSQQPQGGMQGMQGMHPIQQMVHAAPGGGAQMQPQWRQPHQGPLMVPTGPRGPVTQNPGMPSVSSVMEDEILMDLI", "length": 701 }, "evidence": [ { "id": "A0A9J7G4X6", "url": "https://omabrowser.org/oma/group/A0A9J7G4X6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q71SY5-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 25", "gene_name": "MED25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPGSEGPARAGSVVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTENLVQQIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPTDVSQDPRHMVLVRGLVLPVGGGSAPGPLQSKQPVPLPPAAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAPQLPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQQRGMGGQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGTVGASGATGQPQPQGTAQPPPGAPQGPPGAASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI", "length": 747 }, "evidence": [ { "id": "A0A9J7G4X6", "url": "https://omabrowser.org/oma/group/A0A9J7G4X6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VCB2-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 25", "gene_name": "Med25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVPGSEGPARAGGLVADVVFVIEGTANLGPYFEELRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTESLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQQPADVSQDPRHMVLVRGLVLPVGGSSTSGSLQTKQAVPLPPAPASAATLSAAPPQALPPVPPQYQVPGNLSAAQVAAQNAVEAAKSQKAGLGPRFSPINPLQQAAPGVGPPFSQAPAPPLAPVPPGAPKPPPASQPSLVSTVAPGPVLAAPAQPGAPSLAGTVTPGGVNGPSAAQLGGPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPVLGPILEEQARPPQNLLQLRAPQPQPQGAVGASAATGQPQPQGATQAPTGAPQGPPGAAPGPPPSGPILRPQNPGANPQLRSLLLNPAPPQTGVPPPQASLHHLQPPGAPTLLPPHQSMGQPQLGPQLLHPPPAQSWPTQLPQRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI", "length": 745 }, "evidence": [ { "id": "A0A9J7G4X6", "url": "https://omabrowser.org/oma/group/A0A9J7G4X6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VDR1-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 25", "gene_name": "MED25", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEVDQIPLADVVFVIEGSAINGAYINELKTNYILPTLEHFTTGSIDEREYLIAERFATLYGIVVYRTAANLLEPVCSTYGPFLQPQKVMETIERLPLVGGGMESCAHMAEGFAAAHGCFDDISERRQLLDQTSVQRHCILICNSPPYQMPTTESWKYPGKSCEQLAALFNERKINLSIIAPRKMPVLFKLFMKADGDQPITSKNYAKNIRHLVLLKGYSLKERAPSPNSMAAQMAAPNAAQATVQQQQQQQQNQAGQQQQGQGMPMDTTPAQQQQQQQQQQQQQQQQGNPQQQVMNMNTMQQQQPGPNPPAGLLNPQQQQQLLQQQQQNQFVSNQMQNQNFQQNVGPGQNRWMYPNQPGQARPPFMQGAGNVGGVGQGGGMQQNPNSALISRINAPPPNQTVTSLQQQQQQQAQQQQQQQQQAQQQQQQRMQMLSQQQMLNHQQLQQQQQLAQQQQQQQQGQQQQQVNPNAGNNMMPASNAGNMSNPQQQQQQVGQQSNPQQQGNPQQQQQGNSQQEQASLREKIWTGVLEWSEKPKSDQQKIPHTLQCTVCTNIKDGEPEIKAENWPPKLLMQLMPKHLVGNIGGQFLKDSKMVVFRPTPGEALDSLAKMMTSGYAGCVHFSSIPNSPACDLKVLILLYTPDRNAFLGFIPNNQAMFVERLRKVIQQKQHGNMQQQQQQQQMMQQQGKSPMELQQQQQQQQQQQQMQQDNSQQQHYNQFQLNMQMGGGGPGGGPGPGPGGMPMQQNQMQMNMMQQQRMPLGVGVGVGVGPGGVPNPNLQQQLQQVAPNVAAMQQQQAQQQQQRMVRPMMSNNNPGLRQLLQHQTTPGNQFRPQMGGQNPNQMGAGGPMVGNRNFDDGNYEFM", "length": 863 }, "evidence": [ { "id": "A0A9J7G4X6", "url": "https://omabrowser.org/oma/group/A0A9J7G4X6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6" } ], "pmid": "" }, { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G4X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6" }, { "id": "PF11232", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11232" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator complex subunit Med25 PTOV", "eco_id": "ECO_0000259", "start_pos": 393, "end_pos": 542, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G4X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6" }, { "id": "PF11235", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator complex subunit Med25 synapsin 1", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 379, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G4X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6" }, { "id": "PF11265", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11265" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator of RNA polymerase II transcription subunit 25 von Willebrand factor type A", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 226, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G4X6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X6" }, { "id": "PF18658", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18658" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SPIN-DOC-like zinc-finger", "eco_id": "ECO_0000259", "start_pos": 725, "end_pos": 783, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 250 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 272, "end_pos": 274 }, { "start_pos": 748, "end_pos": 750 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G446-1", "uniprot_ac": "A0A9J7G446", "uniprot_id": "A0A9J7G446_CRIGR", "mass": { "chemical_mass": 251906.0, "monoisotopic_mass": 251906.0 }, "refseq": { "ac": "XP_007641939", "name": "death-inducer obliterator 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641939" }, "gene_names": [ { "name": "Dido1", "type": "recommended", "evidence": [ { "id": "A0A9J7G446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ] }, { "name": "Dido1", "type": "synonym", "evidence": [ { "id": "XP_007641939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641939" } ] } ], "protein_names": [ { "name": "Death-inducer obliterator 1", "type": "recommended", "evidence": [ { "id": "A0A9J7G446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446/entry#names_and_taxonomy" } ] }, { "name": "Death-associated transcription factor 1", "type": "synonym", "evidence": [ { "id": "A0A9J7G446", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446/entry#names_and_taxonomy" } ] }, { "name": "death-inducer obliterator 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007641939", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641939" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613943.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007641939", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641939" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dido1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446", "locus": {} } ], "crossref": [ { "id": "cd15639", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15639", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21547", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21547", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757601", "url": "https://www.ncbi.nlm.nih.gov/gene/100757601", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": 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Classification" ] }, { "id": "A0A8C2LUV1", "url": "https://www.orthodb.org/?gene=A0A8C2LUV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G446", "url": "https://www.orthodb.org/?gene=A0A9J7G446", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G469", "url": "https://www.orthodb.org/?gene=A0A9J7G469", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JTV1", "url": "https://www.orthodb.org/?gene=A0A9J7JTV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11477", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11477", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11477:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11477:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46174", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G446-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G469", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G469", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G469-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G469-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0C0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDKGHLSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDTEVDPSEQPPQQHSLSLRRSGRQPKRTERVEEFLTTVRRRGRKSVPVSLEDSSEPTSSTVTDVETASEGSVESSSEVRSGPAPGSSGNEHPASSEKAKGVDEEEDTSDSDSDGLTLKELQNRLRRKREQEPSERPLRGIQNRLRKKRREEDPAETGSVLTGSADESVPLCKPEPEASQGPVSQSEKDDRENQSEGKATQGSKEEGPRDAGKPKPECEVYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETSASAADEQDTGCRPLGADGTDCTSIGVVEQKSGEDQGIKGRIEKAANPSGKKKLKIFQPVVEAPGAAKCIGPGCSNVAQPDSVYCSNDCILKHAAATMRFLSSGKEQKPKPKEKVKMKPEKFSLPKCSVQAGIKISSVHKRLASEKKENPVKKVMVAPRSETCGKEVTCESTTPSWASDHNYNAVKPEKPEKPEKPTALSPTLLSKSMKEDRRAEDRTVAVAAVPKKTIPPGSLMGRQTSPRNLAPKKLPPYASMAGAKPAIKKLPSGFKGTIPKRPWPSATPSGTSARQAGPTPVTAASKKLPGSAAVVGVIRKPMSANASAASPAPGRLGPVSSAPSQPNSQIRQNIRRSLKEILWKRWAVIHVIHFADTALMIVFWISLLGKCPLVYVIPLFILFRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRMKPEELVSKELSMWTEKPTKSVIESRTKLLNESKKNTAKPETIPDMEDSPPVSDSEEQQESVRAAPEKSTKPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSSEDEPAPKKQKLSASAKKEDLKPRHDSSPSDPVPNTADEGIAEILPENASEPDLENMSSLNQERKCFPGPPGDGHPEPSPLDGLSPCSASGGSGVVTTVTVSGRDPRTALSGSCTVTASMAAHLDNSHTSETKLDTLKPALTPAVVPKSILAKPSSSPDPRYLSVPPSPNMSISESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCLDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAKDPVPSKLLPFEGPGLESQRPNIILGLVICQKVKRPTSAGELDKTDEKRARLQQEEAETSVYPKVAATLPSEKKPPKYHLHSADTAASSTTPPGSPPPPPPLPEPPVLKILSSLKPGSTSTVAAPTTSAVITTTAPPVVSASSKTASPLEHILQTLFGKKKSFEPSAKESVGSTLSPHQDPKAKGEDAVSSAAPLLDPIVQQFGQFSKDKALEEEEEGDDRPYDPEEEYNPERAFHTLLAEPGRRHDVENVPETAEREEVAYDPEDETILEEAKVTIDDLPNRMCVKVSSTERPADFATDATNPSLVEQQKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGASMAHFSVSDALMSPPPKSSLAKTDLFSQEQQAQDPSHGALGANHSLDSRHSRDPRQARRLAAENTESEPLPRAPTGSTPGPQGTLPAREMPAAGTAAVQGPALAPEAKESEAVPWAPGENAVLRPEHDMQKCEHPGNPVSLPLDNSHLPAAGDGASRPTAPRRVLLPTPPSTAFPPSFPLQPEAQNFTSGGREPFPGPMFLSQETSLGSSQYEDTRGAQSAGRSDSPVADTEDSREPQLRTGEGTTQFPQPGQRGGGPQPQFPAQREPLPRTFGMSGHHGPGFPGPRGPVPPFSEESIVPNNDGPRGPPPARFGAQKPPIPSLFSGQHGPPPYGDNRGLSPSYLGGPRGGAPAQFEERKDPHGEKREFQDTPYNEMAGAPAQCEGPDQAQFMGNRAPFQFGGQRRPLLTQMKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETPRGPHPGQFEGPRGQAPGFMPGPRGVQPQQFEEQRVNSPPRFAGQRAPAPLPYGGPRGPAPFAEKNEQPPSRFHFQGQSSQPVKPPPRPLLELPSHPPQHRKDRWDDAGPATALPSGAGSGQGPEADGQWATPEFREGKGHEYRSPAFEGRQRERFEGGPKEKPLDEPEAQGLENRQGRAFEDRRRERGRNWSRERDWERSREWDRHREWDKGRDRSSNRDRERDADRAKDWDRNRERSRNRDRDRERRRDRDRSRSRDRDRDRERARDRDRDRGRDRKDRSKSRESPRDLKSEARTSDGGPATAQA", "length": 2302, "header": "tr|A0A9J7G446-1|A0A9J7G446_CRIGR Isoform 1 of Death-inducer obliterator 1 OS=Cricetulus griseus OX=10029 GN=Dido1 PE=4 SV=1 CANONICAL=A0A9J7G446-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446/entry#A0A8C2LUV1-1", "sequence": { "sequence": "MDDKGHLSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDTEVDPSEQPPQQHSLSLRRSGRQPKRTERVEEFLTTVRRRGRKSVPVSLEDSSEPTSSTVTDVETASEGSVESSSEVRSGPAPGSSGNEHPASSEKAKGVDEEEDTSDSDSDGLTLKELQNRLRRKREQEPSERPLRGIQNRLRKKRREEDPAETGSVLTGSADESVPLCKPEPEASQGPVSQSEKDDRENQSEGKATQGSKEEGPRDAGKPKPECEVYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETSASAADEQDTGCRPLGADGTDCTSIGVVEQKSGEDQGIKGRIEKAANPSGKKKLKIFQPVVEAPGAAKCIGPGCSNVAQPDSVYCSNDCILKHAAATMRFLSSGKEQKPKPKEKVKMKPEKFSLPKCSVQAGIKISSVHKRLASEKKENPVKKVMVAPRSETCGKEVTCESTTPSWASDHNYNAVKPEKPEKPEKPTALSPTLLSKSMKEDRRAEDRTVAVAAVPKKTIPPGSLMGRQTSPRNLAPKKLPPYASMAGAKPAIKKLPSGFKGTIPKRPWPSATPSGTSARQAGPTPVTAASKKLPGSAAVVGVIRKPMSANASAASPAPGRLGPVSSAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRMKPEELVSKELSMWTEKPTKSVIESRTKLLNESKKNTAKPETIPDMEDSPPVSDSEEQQESVRAAPEKSTKPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSSEDEPAPKKQKLSASAKKEDLKPRHDSSPSDPVPNTADEGIAEILPENASEPDLENMSSLNQERKCFPGPPGDGHPEPSPLDGLSPCSASGGSGVVTTVTVSGRDPRTALSGSCTVTASMAAHLDNSHTSETKLDTLKPALTPAVVPKSILAKPSSSPDPRYLSVPPSPNMSISESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCLDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAKDPVPSKLLPFEGPGLESQRPNIILGLVICQKVKRPTSAGELDKTDEKRARLQQEEAETSVYPKVAATLPSEKKPPKYHLHSADTAASSTTPPGSPPPPPPLPEPPVLKILSSLKPGSTSTVAAPTTSAVITTTAPPVVSASSKTASPLEHILQTLFGKKKSFEPSAKESVGSTLSPHQDPKAKGEDAVSSAAPLLDPIVQQFGQFSKDKALEEEEEGDDRPYDPEEEYNPERAFHTLLAEPGRRHDVENVPETAEREEVAYDPEDETILEEAKVTIDDLPNRMCVKVSSTERPADFATDATNPSLVEQQKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGASMAHFSVSDALMSPPPKSSLAKTDLFSQEQQAQDPSHGALGANHSLDSRHSRDPRQARRLAAENTESEPLPRAPTGSTPGPQGTLPAREMPAAGTAAVQGPALAPEAKESEAVPWAPGENAVLRPEHDMQKCEHPGNPVSLPLDNSHLPAAGDGASRPTAPRRVLLPTPPSTAFPPSFPLQPEAQNFTSGGREPFPGPMFLSQETSLGSSQYEDTRGAQSAGRSDSPVADTEDSREPQLRTGEGTTQFPQPGQRGGGPQPQFPAQREPLPRTFGMSGHHGPGFPGPRGPVPPFSEESIVPNNDGPRGPPPARFGAQKPPIPSLFSGQHGPPPYGDNRGLSPSYLGGPRGGAPAQFEERKDPHGEKREFQDTPYNEMAGAPAQCEGPDQAQFMGNRAPFQFGGQRRPLLTQMKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETPRGPHPGQFEGPRGQAPGFMPGPRGVQPQQFEEQRVNSPPRFAGQRAPAPLPYGGPRGPAPFAEKNEQPPSRFHFQGQSSQPVKPPPRPLLELPSHPPQHRKDRWDDAGPATALPSGAGSGQGPEADGQWATPEFREGKGHEYRSPAFEGRQRERFEGGPKEKPLDEPEAQGLENRQGRAFEDRRRERGRNWSRERDWERSREWDRHREWDKGRDRSSNRDRERDADRAKDWDRNRERSRNRDRDRERRRDRDRSRSRDRDRDRERARDRDRDRGRDRKDRSKSRESPRDLKSEARTSDGGPATAQA", "length": 2263, "header": "tr|A0A8C2LUV1-1|A0A8C2LUV1_CRIGR Computationally mapped isoform of Death-inducer obliterator 1 OS=Cricetulus griseus OX=10029 GN=Dido1 PE=4 SV=1 CANONICAL=A0A9J7G446-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G446-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446/entry#A0A9J7G446-1", "sequence": { "sequence": "MDDKGHLSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDTEVDPSEQPPQQHSLSLRRSGRQPKRTERVEEFLTTVRRRGRKSVPVSLEDSSEPTSSTVTDVETASEGSVESSSEVRSGPAPGSSGNEHPASSEKAKGVDEEEDTSDSDSDGLTLKELQNRLRRKREQEPSERPLRGIQNRLRKKRREEDPAETGSVLTGSADESVPLCKPEPEASQGPVSQSEKDDRENQSEGKATQGSKEEGPRDAGKPKPECEVYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETSASAADEQDTGCRPLGADGTDCTSIGVVEQKSGEDQGIKGRIEKAANPSGKKKLKIFQPVVEAPGAAKCIGPGCSNVAQPDSVYCSNDCILKHAAATMRFLSSGKEQKPKPKEKVKMKPEKFSLPKCSVQAGIKISSVHKRLASEKKENPVKKVMVAPRSETCGKEVTCESTTPSWASDHNYNAVKPEKPEKPEKPTALSPTLLSKSMKEDRRAEDRTVAVAAVPKKTIPPGSLMGRQTSPRNLAPKKLPPYASMAGAKPAIKKLPSGFKGTIPKRPWPSATPSGTSARQAGPTPVTAASKKLPGSAAVVGVIRKPMSANASAASPAPGRLGPVSSAPSQPNSQIRQNIRRSLKEILWKRWAVIHVIHFADTALMIVFWISLLGKCPLVYVIPLFILFRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRMKPEELVSKELSMWTEKPTKSVIESRTKLLNESKKNTAKPETIPDMEDSPPVSDSEEQQESVRAAPEKSTKPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSSEDEPAPKKQKLSASAKKEDLKPRHDSSPSDPVPNTADEGIAEILPENASEPDLENMSSLNQERKCFPGPPGDGHPEPSPLDGLSPCSASGGSGVVTTVTVSGRDPRTALSGSCTVTASMAAHLDNSHTSETKLDTLKPALTPAVVPKSILAKPSSSPDPRYLSVPPSPNMSISESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCLDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAKDPVPSKLLPFEGPGLESQRPNIILGLVICQKVKRPTSAGELDKTDEKRARLQQEEAETSVYPKVAATLPSEKKPPKYHLHSADTAASSTTPPGSPPPPPPLPEPPVLKILSSLKPGSTSTVAAPTTSAVITTTAPPVVSASSKTASPLEHILQTLFGKKKSFEPSAKESVGSTLSPHQDPKAKGEDAVSSAAPLLDPIVQQFGQFSKDKALEEEEEGDDRPYDPEEEYNPERAFHTLLAEPGRRHDVENVPETAEREEVAYDPEDETILEEAKVTIDDLPNRMCVKVSSTERPADFATDATNPSLVEQQKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGASMAHFSVSDALMSPPPKSSLAKTDLFSQEQQAQDPSHGALGANHSLDSRHSRDPRQARRLAAENTESEPLPRAPTGSTPGPQGTLPAREMPAAGTAAVQGPALAPEAKESEAVPWAPGENAVLRPEHDMQKCEHPGNPVSLPLDNSHLPAAGDGASRPTAPRRVLLPTPPSTAFPPSFPLQPEAQNFTSGGREPFPGPMFLSQETSLGSSQYEDTRGAQSAGRSDSPVADTEDSREPQLRTGEGTTQFPQPGQRGGGPQPQFPAQREPLPRTFGMSGHHGPGFPGPRGPVPPFSEESIVPNNDGPRGPPPARFGAQKPPIPSLFSGQHGPPPYGDNRGLSPSYLGGPRGGAPAQFEERKDPHGEKREFQDTPYNEMAGAPAQCEGPDQAQFMGNRAPFQFGGQRRPLLTQMKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETPRGPHPGQFEGPRGQAPGFMPGPRGVQPQQFEEQRVNSPPRFAGQRAPAPLPYGGPRGPAPFAEKNEQPPSRFHFQGQSSQPVKPPPRPLLELPSHPPQHRKDRWDDAGPATALPSGAGSGQGPEADGQWATPEFREGKGHEYRSPAFEGRQRERFEGGPKEKPLDEPEAQGLENRQGRAFEDRRRERGRNWSRERDWERSREWDRHREWDKGRDRSSNRDRERDADRAKDWDRNRERSRNRDRDRERRRDRDRSRSRDRDRDRERARDRDRDRGRDRKDRSKSRESPRDLKSEARTSDGGPATAQA", "length": 2302, "header": "tr|A0A9J7G446-1|A0A9J7G446_CRIGR Isoform 1 of Death-inducer obliterator 1 OS=Cricetulus griseus OX=10029 GN=Dido1 PE=4 SV=1 CANONICAL=A0A9J7G446-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G469-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446/entry#A0A9J7G469-1", "sequence": { "sequence": "MDDKGHLSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDTEVDPSEQPPQQHSLSLRRSGRQPKRTERVEEFLTTVRRRGRKSVPVSLEDSSEPTSSTVTDVETASEGSVESSSEVRSGPAPGSSGNEHPASSEKAKGVDEEEDTSDSDSDGLTLKELQNRLRRKREQEPSERPLRGIQNRLRKKRREEDPAETGSVLTGSADESVPLCKPEPEASQGPVSQSEKDDRENQSEGKATQGSKEEGPRDAGKPKPECEVYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETSASAADEQDTGCRPLGADGTDCTSIGVVEQKSGEDQGIKGRIEKAANPSGKKKLKIFQPVVEAPGAAKCIGPGCSNVAQPDSVYCSNDCILKHAAATMRFLSSGKEQKPKPKEKVKMKPEKFSLPKCSVQAGIKISSVHKRLASEKKENPVKKVMVAPRSETCGKEVTCESTTPSWASDHNYNAVKPEKPEKPEKPTALSPTLLSKSMKEDRRAEDRTVAVAAVPKKTIPPGSLMGRQTSPRNLAPKKLPPYASMAGAKPAIKKLPSGFKGTIPKRPWPSATPSGTSARQAGPTPVTAASKKLPGSAAVVGVIRKPMSANASAASPAPGRLGPVSSAPSQPNSQIRQNIRRSLKEILWKRWAVIHVIHFADTALMIVFWISLLGKCPLVYVIPLFILFRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRMKPEELVSKELSMWTEKPTKSVIESRTKLLNESKKNTAKPETIPDMEDSPPVSDSEEQQESVRAAPEKSTKPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSSEDEPAPKKQKLSASAKKEDLKPRHDSSPSDPVPNTADEGIAEILPENASEPDLENMSSLNQERKCFPGPPGDGHPEPSPLDGLSPCSASGGSGVVTTVTVSGRDPRTALSGSCTVTASMAAHLDNSHTSETKLDTLKPALTPAVVPKSILAKPSSSPDPSISESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCLDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAKDPVPSKLLPFEGPGLESQRPNIILGLVICQKVKRPTSAGELDKTDEKRARLQQEEAETSVYPKVAATLPSEKKPPKYHLHSADTAASSTTPPGSPPPPPPLPEPPVLKILSSLKPGSTSTVAAPTTSAVITTTAPPVVSASSKTASPLEHILQTLFGKKKSFEPSAKESVGSTLSPHQDPKAKGEDAVSSAAPLLDPIVQQFGQFSKDKALEEEEEGDDRPYDPEEEYNPERAFHTLLAEPGRRHDVENVPETAEREEVAYDPEDETILEEAKVTIDDLPNRMCVKVSSTERPADFATDATNPSLVEQQKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGASMAHFSVSDALMSPPPKSSLAKTDLFSQEQQAQDPSHGALGANHSLDSRHSRDPRQARRLAAENTESEPLPRAPTGSTPGPQGTLPAREMPAAGTAAVQGPALAPEAKESEAVPWAPGENAVLRPEHDMQKCEHPGNPVSLPLDNSHLPAAGDGASRPTAPRRVLLPTPPSTAFPPSFPLQPEAQNFTSGGREPFPGPMFLSQETSLGSSQYEDTRGAQSAGRSDSPVADTEDSREPQLRTGEGTTQFPQPGQRGGGPQPQFPAQREPLPRTFGMSGHHGPGFPGPRGPVPPFSEESIVPNNDGPRGPPPARFGAQKPPIPSLFSGQHGPPPYGDNRGLSPSYLGGPRGGAPAQFEERKDPHGEKREFQDTPYNEMAGAPAQCEGPDQAQFMGNRAPFQFGGQRRPLLTQMKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETPRGPHPGQFEGPRGQAPGFMPGPRGVQPQQFEEQRVNSPPRFAGQRAPAPLPYGGPRGPAPFAEKNEQPPSRFHFQGQSSQPVKPPPRPLLELPSHPPQHRKDRWDDAGPATALPSGAGSGQGPEADGQWATPEFREGKGHEYRSPAFEGRQRERFEGGPKEKPLDEPEAQGLENRQGRAFEDRRRERGRNWSRERDWERSREWDRHREWDKGRDRSSNRDRERDADRAKDWDRNRERSRNRDRDRERRRDRDRSRSRDRDRDRERARDRDRDRGRDRKDRSKSRESPRDLKSEARTSDGGPATAQA", "length": 2291, "header": "tr|A0A9J7G469-1|A0A9J7G469_CRIGR Computationally mapped isoform of Death-inducer obliterator 1 OS=Cricetulus griseus OX=10029 GN=Dido1 PE=4 SV=1 CANONICAL=A0A9J7G446-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H0C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446/entry#A0A9J7H0C0-1", "sequence": { "sequence": "MDDKGHLSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDTEVDPSEQPPQQHSLSLRRSGRQPKRTERVEEFLTTVRRRGRKSVPVSLEDSSEPTSSTVTDVETASEGSVESSSEVRSGPAPGSSGNEHPASSEKAKGVDEEEDTSDSDSDGLTLKELQNRLRRKREQEPSERPLRGIQNRLRKKRREEDPAETGSVLTGSADESVPLCKPEPEASQGPVSQSEKDDRENQSEGKATQGSKEEGPRDAGKPKPECEVYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETSASAADEQDTGCRPLGADGTDCTSIGVVEQKSGEDQGIKGRIEKAANPSGKKKLKIFQPVVEAPGAAKCIGPGCSNVAQPDSVYCSNDCILKHAAATMRFLSSGKEQKPKPKEKVKMKPEKFSLPKCSVQAGIKISSVHKRLASEKKENPVKKVMVAPRSETCGKEVTCESTTPSWASDHNYNAVKPEKPEKPEKPTALSPTLLSK", "length": 531, "header": "tr|A0A9J7H0C0-1|A0A9J7H0C0_CRIGR Computationally mapped isoform of Death-inducer obliterator 1 isoform X5 OS=Cricetulus griseus OX=10029 GN=Dido1 PE=4 SV=1 CANONICAL=A0A9J7G446-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446/entry#A0A9J7JTV1-1", "sequence": { "sequence": "MDDKGHLSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDTEVDPSEQPPQQHSLSLRRSGRQPKRTERVEEFLTTVRRRGRKSVPVSLEDSSEPTSSTVTDVETASEGSVESSSEVRSGPAPGSSGNEHPASSEKAKGVDEEEDTSDSDSDGLTLKELQNRLRRKREQEPSERPLRGIQNRLRKKRREEDPAETGSVLTGSADESVPLCKPEPEASQGPVSQSEKDDRENQSEGKATQGSKEEGPRDAGKPKPECEVYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETSASAADEQDTGCRPLGADGTDCTSIGVVEQKSGEDQGIKGRIEKAANPSGKKKLKIFQPVVEAPGAAKCIGPGCSNVAQPDSVYCSNDCILKHAAATMRFLSSGKEQKPKPKEKVKMKPEKFSLPKCSVQAGIKISSVHKRLASEKKENPVKKVMVAPRSETCGKEVTCESTTPSWASDHNYNAVKPEKPEKPEKPTALSPTLLSKFCPCVSFTSLKYLPVNLRSCGSKGY", "length": 556, "header": "tr|A0A9J7JTV1-1|A0A9J7JTV1_CRIGR Computationally mapped isoform of Death-inducer obliterator 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Dido1 PE=4 SV=1 CANONICAL=A0A9J7G446-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1626, "start_aa": "Thr", "end_pos": 1626, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1626", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 607, "start_aa": "Thr", "end_pos": 607, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr607", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 619, "start_aa": "Thr", "end_pos": 619, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr619", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757601", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757601", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZXE0-1", "protein_name": "Death-inducer obliterator 1", "gene_name": "Dido1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDKGDLSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDTEVDPSEQQPQQHNLSLRRSGRQPKRTERVEEFLTTVRRRGRKNVPVSLEDSSEPTSSTVTDVETASEGSVESSSEIRSGPAPGTLGKEHPSSSEKVKGGDEEEDTSDSDSDGLTLKELQNRLRRKREQEPVERSLRGIQNRLRKQRREEDPAEAGSVQIGSIEEDTPRCKQEPEASQGPVSQSEKDDRENQLEGKATQGSKEESPREAGKPKPECEVYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETSSSAADEQDAGCRPVGADGTDCTSIGTVEQRSGEDQGIKGRIEKAANPSGKKKLKIFQPVVEAPGAAKCIGPGCSNVAQPDSVYCSNDCILKHAAATMKILSSGKEQKPKPKEKVKMKPEKFSLPKCSVQAGIKISSVHKRLASEKRENPVKKVTLASRSETSVKEATCESTPSWASDHNYNAVKPEKPEKPEKPTALSPTLLSKSMKDDKRVEDRTVAAAAVPKKAVPPGSVMGRQTSPRNLVPKKLPPYPNMAGAKTAVKKLPSGFKGTIPKRPWPSATLSGTSARQAGPTPVIAASKKLPGSAAVVGIARKPMSANVPAASPVPGRLGPVSPAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRMKPEELVSKELSMWTEKPTKSVIESRTKLLNESKKNSTKPETIPDMEDSPPVSDSEEQESVRAAPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSSEDEPAPKKQKLSASSKKEDLKARHDSSPPDAVPSTADEGIAETPENTCDPDLETVSSLNQERKGFPESAGDSHPEPSSLDGLSSSFASGGSGVVTTVTVSGRDPRTALSGSCTVTASMAAHMDNSQTSETKLEILKPALTSAVVPKSILAKPSSSPDPRYLSVPPSPNTSISESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCLDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAKDPVPSKLLPFEGPGLESPRPNIILGLVICQKVKRPSSAGELDKTDEKRPRLQQEETETSVYPKVTAALPSEKKPPKYSVHSADTTASSTTPPGSPPPPPPLPEPPVLKILSSLKPGSTSTVTAPTTSAVITTTASPVTAATSKTASPLEHILQTLFGKKKSFEPSGKESVGSTLAPHHDSKAKGEDTMSAAPLLDPIVQQFGQFSKDKALEEEEEDDRPYDPEEEYNPDRAFHTLLAEPGRPHDVPSVPETAEREEVAYDPEDETILEEAKVTIDDLPNRMCVKVSSTERPADFSTDASSASLVEQQKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGVSMAHFSVSDALMSPPPKSSLGKTELFSQEQQALDPSQGSLSTNHSLDSRQSRDPRQARRLAAENTENESLPRAPTGSTSGPQGTLPARETPAGAAVAQGPGLAAEAKESMASPWAPGENTVLRPEHDIQKCEHSSNPVSLPLDTSHLPTAGDGTARPAPPRRVLLPTPPSTTFPPSFPLQPEAQNFSSGGREPFSGPTFLSQETSLGSSQYEDPRGAQSAGRSDSPVADMEDSREPQPRPGEGATSFPSPAQRGGGPQPQFPGQREPAPRTFGMSGHHGPSFPGPRGPVPPFSEENIVPNSDGSRGPPPPRFGAQKPPIPSLFSGQHGPPPYGDNRGLSPSYLGGPRGGAPAQFEDRKDPHGEKREFQDTPYEMTGAPAQCEGPDQAQFMGNRAPFQFGGQRRPLLTQIKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETSRGTHPGQFEGARGQAPGFMPGPRGVQPQQFEEQRVNSPPRFAGQRASAPLPYGGPRGPAPFPEKNEQPPSRFHFQGPSSQPVKPPPRPLLELPSHPPQHRKDRWDEAGTATALPPSSGPGQGHEADGQWATSEFREGKGHEYRSPAFEGRQRERFEAGPKEKPLDEPEAQGLESRQGRAFEDRRRERERGRNWSREKDWERSRDWDRHREWDKGRDRSSNRDRERDTDRGKEWDRSRERSRNRDRDRERRRDRDRSRSRDRDRDRERARDRDRDRGRDRKDRSKSRESPRDLKPEARTSEGGPAAAQA", "length": 2258 }, "evidence": [ { "id": "A0A9J7G446", "url": "https://omabrowser.org/oma/group/A0A9J7G446/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZVZ7-1", "protein_name": "Death-inducer obliterator 1", "gene_name": "DIDO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCDELEILNREIERLLQSSSVEGSTLSNSDCLQTSQTDSLDVITGSDSGAKYQLEQESSEKEFLVLAPADNSERRSGASGSRNSACAGRIMLNDSDPLLPSSGSPFNSAQQGETVQTSNAVSVFQGGESGVYTMEQAVSLQPVSMESESNTDNMENSSPASALDEKGEQSNEEEQKSIKPTSKEFRKTWGFRRTTIAKREGAGDIDMDSSEQQPQQQQQSLNLRRSGRQPKRTERVEEFLTTVRRRGRRNAPIALEDSSEPASCPATDAETASEDSVESASDIKSGTRRTGTRNSKDQKGSKNRRTKEEEEEEDEEEEEEEDTSDSDSDGLTLKELQNRLRNKRVEQKPTQLTLKEMQNRLRKRTSEQDPAETDNVQSDQPVKTELSVKQEPDIVDNTEIASQVVVSEENTEDLQVQKEIKPAAGAKGIADEEPEELPKSKPESEIYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQGQDESISETDQQEAKAGQVNVDGTEFTSIGTIEHKSVEDQGIKGRIEKAANPSGKKKLKIFQPVVDAPGVSKCIGPGCFNVAQPDSVYCSNDCILKHAAATMKYLSTGKDTKPKPKEKTKPKSEKPGVTKSHLQASTKPLSNQKRQFPEKKETNVKKTVLSAAKTEANTQPIAREPAAENTTPSWASDHNYNAVKPEKTAAISSSLLFKSQKGEKKKEDKAAEHTVASKRAVASTSVAEKQTSSLTKNLLPKKAPTFSSLPLTKQPLKSSTGSFKGVIPKKPWPSSDSVPSKPSAPPGSSLPKKPVASSSLGAGLKRPAPSSVPTASGSSQVKVSAIPIQSQPNSQIRQNIRRSLKEILWKRVNDSDDLVMTESEVGKVALNIEKEMFNLFHVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLHGEISLSKLVRMKPEELLSKELSVWKEKPAKAVIESRKKSHEVKKVAVKREHAPDVNMEDSPPVSDSDEQQESARNVPKSNSAPSLDVFSSMLKDTTSQHRAHLFDLNCKICTGQISASEDEVPAKKSKTVASVKKVETKSKPEVQQKYESSAPPAAAEPAKEAVSEDAMETDVEPAAEVVSQSNIERSYIPTTQVQNDTDSSVPEEASALPAVCAGGVVTTVTVSGRDPRTALGSASAAAATAPRSGPASEKVSVGESKQETSKPVMTVPKSILTKPSSSPDPRYLAVHQLPSINVAEPRSPQDSDTSLFLSRLNTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRISPKTVWDYVGKLKSSLSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSSKDPIPSKLLPFEGPGLESSRPNLILGLVICQKGKRPATGMETDKIEEKRSRIQLQEEAEPSQFLKGPTASFQEKKTPKYTLYSGDSAVSTTPPGSPPPPPPPLPVPESSAVTPSVLKILSSIKSGSTTTAPPPVSATASPSVTATHSSSSKTATPLEHILQTLFGKKKSFEPAAKESETAQSSNQKAQAAAEGGMAAVPLLDPIVQQFGQMSKDKAIEEEEDDRPYDPEEEYDPEKAFEMQTGESEKLYSVEKPSNTAVLEDEAYDPEDETILEEAKVTVDDLPNKMYTDAKSSATETPAPYVPDLSASSSLVEQQKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGVSMAHFSVSDALMSPPPKSSLIKTELFQQGQQAVQKVDLPSSANQQAQVLNQGSDPRQTRDPRQARRMATEINDNNDARIKPQAVQSETPAREILPASFPSALSASLGKEDNTLMSAPQLSYTGDNWVSGEQACTVSQKEVSSSKFENTAQVNLENVNQTVPGEPSTSKPLRKVLLPTPPTTCFQPNFSTPNDSQSLQDMHQVSWPNEPKEAIGRDSFPNAMFTSQENAGGHYEPERGLSSLQYEEQRNPQPHQFVEQTESTSIQGEGGPLPQHFEENRLPFSLPGQKGGPPQPPIHNAPGGPHGPNFRGPAPQFSEEHGSPNSDGQRGPAPGRFGPQKGPIPSLFSSQHGSPLFGDNRGPAPSYGVPRGMSPSQFEDHMEPHMEQREFSDSQYNEMIRPPGQFEGSDQPQFMGNRGPFPFGGQRRPPPAQFKGQRGGPQFGGPRGPAPGHFGGPRGPHTNQFEGQRGPAPNHGPGPRGLLPQPFEERRGSPPPRFANQRGPAPPQYGGPRGPSPALFPEQNEPPSRFHFQGQSQQSMKSTPRPLLDLPGHLSAHRKEMWEEAGPSASLPNVSGQGHESEGQWSASDFRESKNIEYRGQTFEGRQRERYEGGNKDKGLDQPEPQQADNRQGRPFEERRRDREHGRPWERDRGRNWNRDRDWERHRDKEWDKNRDRNQNKDREKDSEHAKDWERSRDRDRARTRDRESYRRRDRERSRSRDRDRDRDKDRDRDRSREKERDRERDRDRERGKDRKDRSKTRETGKEVKPEAPKESQKPTETEASSSTSQS", "length": 2493 }, "evidence": [ { "id": "A0A9J7G446", "url": "https://omabrowser.org/oma/group/A0A9J7G446/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BCR2-1", "protein_name": "Death-inducer obliterator 1", "gene_name": "DIDO1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDDKGDPSGEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEVDTLEPSPRQQQSPSLRRSGRQPKRTERVEEFLTTVRRRGRRSAPVSLEDSGEPASCPATDAETASEGSVESASDGKSGPRSSSTGAKQRLASSAKAREGEDEDDTSDSDSDGLTLKELQNRLRKKREQEPADRPTRGIQNRLRRKRREEDPAETVDVQAGDVMEGSLPASREPEGDLGAAAQAVKEDREGRQDGRVAPGGRAEEAADSIRHKPECEVYDPSALYCLCRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDEASSEATDMQDTRSGPLGADSTDFTSIGTVEQKSSEDQGIKGRIEKAANPSGKKKLKIFQPVVEAPGAAKCIGPGCSSVAQPDSVYCSNDCILKHAAATMRFLSAGKEQKPKAKEKLKTKPEKIVLQKCSVQAGIKISSVHKRLASDKKENAVKKAAVAPPRNEVLTKEPVCESSTPSWASDHNYNAVKPEQTAAPWPPLLYKSVKEDRRMEDKMAVVVAKKLAPPGSSGAGRQPPGRNLLPKKSPSFANTAVAKPTVRKSPSGFKGTIPKRPWLSSTTSPSGSAPSAKQAGLVTAAATSASRKFPSSTASVGAVRKPGSTSVPLASPAPGRLGPVSPASSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALLIEKEMFNLFRVTDNRYKSKYRSLMFNLKDPKNQGLFHRVLREEISLAKLVRMKPEELVSKELSVWRERTTKPVMESRTKLHNETKKPAIKQEAVPDMEDSPPVSDSDEQQESVRAAPERSAAPLPGVFSSMLQDTTSQHRAHLFDLNCKICTGQVPSSEDEPAPKKQKLSASVKKEESKSKRDSPPPDPVLSEADDAAPETPPENASEPDLESAAHTHLEGKYLPVPLEDNQPEPPALEGLPCPTPGGGSVLTMVTMSGRDPRTALGGPSTATASAATHLEGTTPAEPRQDVPKPVPPSVTVPKSILAKPSASPEPRYLLSVPPSPSISISESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYIGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRDRFGVVANNSRHVKDLYLIPLSATDPIPSKLLPFEGPGLESPRPNIILGLVICQKTKRPSGAGELDKTEEKRARLLTQDEVEPVHPKVPAALPPEKRPTKYQLCPGDAAVSTTPPGSPPPPPPPPEAPGAPGSSSMLKILSTLKPGATAPSGTAAAAPAAASSVSSTSKTASPLEHILQTLFGKKKSFDPLSKEPVESAPAPHQDSKAKTDGGLTAAPLLDPIVQQFGQISKDRALEEEEDDRPYDPEEEYGPERALDTPPSDRTRHQDAEEAPEAAEREEVAYDPEDETILEEAKVTIDDLPNRMCVDTRGGPGLSAPSLVEQQKMIEELNKQIEEQKRQVEEQEEALRQQRAAVGASMAHFSVSDALMSPPPKATLPKAELFPQEPQAAVKPAPAPATNQAPGPNAEARLSRDPRQARRLAVENNESEAALRAPPAREAPGGVSAGPGLLPAQEEPESAPPPWTPGEEAPLPAKQDGPPHEPSETLGPESMAGLDAVARPARKVLLPTPPGASFQPLYPPQSEGQAFPPPGFSGPMYAPQENPMGSSQYDDPRNAQFAEKSDALATDTEGDREPQPRPGEGAGVFPALAQKGGPPPQFQGQREPTPRAFGMSGLHGPSFPAPRGPVPPFSEENTNNDGPRGGPPPARFGPPKGPIPSLFSGPHGPPPYGDGRGPSPSHLGGPRGAGPPLLEERKDAHGEKREYPDALYGEASGGPAQCEGPEQAPFPGGRGATPFQFGGQRRPLLSQFKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPGQFEGPRGQAPGFVPGPRGMQPQQFEEQRVHSPPRFSGQRAPAPLPFGGPRGGAPFPEKSEPVPPRFHFQGPAPPGPKPAPRPLLELPSHPPAPSAAPAQGPEADFREGGRGHEYRGPAFEGRPRDKAPEDPEAPPPDSRSGRALDDRRRERERGKPWERERGRTWSRERDWDRGRDWDRHRDKDAGRDWDRSRERNGSRDKGREWDRGRERSRNRDRDRRRDRERSRSRDRDRDKARERERRRDRSRSPERPRDPKTETPRAAAPTAQT", "length": 2196 }, "evidence": [ { "id": "A0A9J7G446", "url": "https://omabrowser.org/oma/group/A0A9J7G446/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8C9B9-1", "protein_name": "Death-inducer obliterator 1", "gene_name": "Dido1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDKGHLSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDTEVDPSEQQPQQHNLSLRRSGRQPKRTERVEEFLTTVRRRGKKNVPVSLEDSSEPTSSTVTDVETASEGSVESSSEIRSGPVSDSLGKEHPASSEKAKGGEEEEDTSDSDSDGLTLKELQNRLRRKREQEPVERSLRGSQNRLRKKRREEDSAETGSVQIGSAEQDRPLCKQEPEASQGPVSQSETDDIENQLEGKATQGNTEENPREAGKPKPECEVYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETNGSATDEQDSGCRSVGADGTDCTSIGTVEQKSGEDQGIKGRIEKAANPSGKKKLKIFQPVVEAPGAPKCIGPGCSSVAQPDSVYCSNDCILKHAAATMRFLSSGKEQKTKPKEKVKTKPEKFSLPKCSVQVGIKISSVHKRLASEKRENPVKKVMLASRSETSGKEAACESSTPSWASDHNYNAVKPEKPEKPTALSPTLLSKSMKDDRRVEDRTMAAVTIPKKALPSASLVGRQTSPRNLVPKKLPPYSNMAGAKPAIKKLPSGFKGTIPKRPWPSATLSGTSARQAGPTPMTAASKKLPGSAAVVGVTRKPMSANVPAASPAPGRLGPVSPAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRMKPEELVSKELSMWTEKPTKSVIESRTKLLNESKKNTTKPETIPDMEDSPPVSDSEEQQESVRAAPEKSAAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSSEDEPAPKKQKLSASSKKEDFKPRHDSSPPNAVPNTADEGIADTLPENASEPDPESTSSLNQERKCFPESPGDSHPEPSSLGGLSPSSASGGSGVVTTVTMSGRDPRTALSGSCTVTASMAAHLDNSQASETKLDMIKPALTSAVVPKSILAKPSSSPDPRYLSVPPSPSISESRSPPEGDTTLFLSRLNTIWKGFINMQSVAKFVTKAYPVSGCLDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAKDPVPSKLLPFEGPGLESPRPNIILGLVICQKVKRPSSAGELDKTDEKRTRLQQEELETSVYPKVTAALPSEKKPPKYSVHSIDTAATSTTPPGSPPPPPPLPEPPVLKILSSLKPGSTSTVTAPTTAAITTTASPVTAATSKTASPLEHILQTLFGKKKSFEPSGKESVGSTLSPHQDSKAKGEDTMSAAPLLDPIVQQFGQFSKDKALEEEEEDDRPYDPEEEYNPDRAFHTLLAEPGRPHDVQSVSETAEREEVAYDPEDETILEEAKVTIDDLPNRMCMKVSATERPADFTTDASSASLVEQQKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGVSMAHFSVSDALMSPPPKSSLGKTELFSQEQQAPDPSQGAPNTNHNLDSRQSRDPRQARRLAAENTENESLPRAPTGSTPGPQGTLPARETPAGTAVVQGPGLAAEAKESMAVPWAPGENAVLRPEHDIQKCEHPGNPVSLPLDTSHLPTAGDGAARPAPPRRVLLPTPPSTTFPPSFPLQPKAQNFSSGSREPFSGPTFMSQETSLGSSQYEDPRGAQSAGKNDSPVADMEDSREPQPRPGESTTSFPQPGQRGGGPQPQFPGQREPAPRTFGMSGHHGPSFPGPRGPVPPYSEENLVPNSDGPRGPPPARFGAQKPPIPSLFSGQHGPPPYGDNRGLSPSYLGGPRGGAPAQFEDRKDPHGEKREFQDTPYNEMTGAPAQCEGPDQAQFMGNRAPFQFGGQRRPLLTQMKGPRGGPPPSQFGAQRGPPPGHFVGPRGPHPSQFENSRGTHPGQFEGARGQAPGFMPGPRGIQPQQFEEQRVNSPPRFAGQRASAPLPYGGPRGPAPFPEKNEQPPSRFHFQGPSSQPVKPPPRPLLELPSHPPQHRKDRWDEAGPATALPSSAGPGQGHEADGQWATSEFREGKGHEYRSPAFEGRQRERFEAGSKEKPLDEPEAQGLESRQGRAFEDRRRERERGRNWSRERDWERSRDWDRHREWDKGRDRSSNRDRERDNDRAKEWDRSRERSRNRDRDRERRRDRDRSRSRDRDRDRERARDRDRDRGRDRKDRSKSRESPRDQKPEARTSEGGPAAAQA", "length": 2256 }, "evidence": [ { "id": "A0A9J7G446", "url": "https://omabrowser.org/oma/group/A0A9J7G446/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BTC0-4", "protein_name": "Death-inducer obliterator 1", "gene_name": "DIDO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDKGDPSNEEAPKAIKPTSKEFRKTWGFRRTTIAKREGAGDAEADPLEPPPPQQQLGLSLRRSGRQPKRTERVEQFLTIARRRGRRSMPVSLEDSGEPTSCPATDAETASEGSVESASETRSGPQSASTAVKERPASSEKVKGGDDHDDTSDSDSDGLTLKELQNRLRRKREQEPTERPLKGIQSRLRKKRREEGPAETVGSEASDTVEGVLPSKQEPENDQGVVSQAGKDDRESKLEGKAAQDIKDEEPGDLGRPKPECEGYDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQVQDETHSETADQQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPSGKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKPKPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAACESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPAPRNLVPKKSSFANVAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSVMESRTKLHNESKKTAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKSTAPLLDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDSSAPDPAPDSADEVMPEAVPEVASEPGLESASHPNVDRTYFPGPPGDGHPEPSPLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKPVLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFINMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPGLESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQFSKDKALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEAAAAEREEVAYDPEDETILEEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQQKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGVSMAHFSVSDALMSPPPKSSLPKAELFQQEQQSADKPASLPPASQASNHRDPRQARRLATETGEGEGEPLSRLSARGAQGALPERDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPAGSEQDGWKAEPGEGTRPATVGDSSARPARRVLLPTPPCGALQPGFPLQHDGERDPFTCPGFASQDKALGSAQYEDPRNLHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPNFPGPRGPAPPFPEENIASNDGPRGPPPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPSYLGGPRGVAPSQFEERKDPHGEKREFQDAPYNEVTGAPAQFEGTEQAPFLGSRGGAPFQFGGQRRPLLSQLKGPRGGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNFMPGPRGIQPQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDAGTASQA", "length": 2240 }, "evidence": [ { "id": "A0A9J7G446", "url": "https://omabrowser.org/oma/group/A0A9J7G446/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ], "pmid": "" }, { "name": "apoptotic signaling pathway", "id": "GO:0097190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097190", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G446", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G446" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1071, "end_pos": 1073, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1591, "end_pos": 1593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1734, "end_pos": 1736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2186, "end_pos": 2188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" }, { "start_pos": 949, "end_pos": 951, "annotation": "n_glycosylation_sequon" }, { "start_pos": 957, 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829, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 607, 619, 1626 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1071, "end_pos": 1073 }, { "start_pos": 1591, "end_pos": 1593 }, { "start_pos": 1734, "end_pos": 1736 }, { "start_pos": 2186, "end_pos": 2188 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 645, "end_pos": 647 }, { "start_pos": 726, "end_pos": 728 }, { "start_pos": 826, "end_pos": 828 }, { "start_pos": 949, "end_pos": 951 }, { "start_pos": 957, "end_pos": 959 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G450-1", "uniprot_ac": "A0A9J7G450", "uniprot_id": "A0A9J7G450_CRIGR", "mass": { "chemical_mass": 46293.0, "monoisotopic_mass": 46293.0 }, "refseq": { "ac": "XP_027275667", "name": "protein LSM14 homolog B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275667" }, "gene_names": [ { "name": "Lsm14b", "type": "recommended", "evidence": [ { "id": "A0A9J7G450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ] }, { "name": "Lsm14b", "type": "synonym", "evidence": [ { "id": "XP_027275667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275667" } ] } ], "protein_names": [ { "name": "Protein LSM14 homolog B isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7G450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450/entry#names_and_taxonomy" } ] }, { "name": "protein LSM14 homolog B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027275667", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275667" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275667" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lsm14b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450", "locus": {} } ], "crossref": [ { "id": "A0A9J7G450", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G450", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01736", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01736", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769638", "url": "https://www.ncbi.nlm.nih.gov/gene/100769638", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769638", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769638", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G450", "url": "https://www.orthodb.org/?gene=A0A9J7G450", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13586", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13586", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13586:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13586:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275667", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275667", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MKW4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MKW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G450-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKH6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTT9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRPAPPREEIYEYIIFRGSDIKDITVCEPPKAQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFRGMPPYGQLAASSLLSQQYAASLGLEKLVSPPASAAASSPSSSPSPQPVSELDMSSEPPQLTSKGAGFPSTPVSKSPMVEQAVQTSSADNLNAKKLLPSKVTSGTQLNGRQAQPSSKTASDVVQPTPVHTQGQVNDENRRPPRRRSGNRRTRNRSRGQNRPTNVKENTIKFEGDFDFESANAQFNREELDKEFKKKLNFKDDKAEKGEEKDPAVMTQSEETPAEEDLLGPNCYYDKSKSFFDNISSELKTSSRRTTWAEERKLNTETFGVSGRFLRGRSSRGGFRGGRGNGTTRRNPTSHRAGTGRV", "length": 424, "header": "tr|A0A9J7G450-1|A0A9J7G450_CRIGR Isoform 1 of Protein LSM14 homolog B isoform X2 OS=Cricetulus griseus OX=10029 GN=Lsm14b PE=3 SV=1 CANONICAL=A0A9J7G450-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MKW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450/entry#A0A8C2MKW4-1", "sequence": { "sequence": "MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRPAPPREEIYEYIIFRGSDIKDITVCEPPKAQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFRGMPPYGQLAASSLLSQQYAASLGLGAGFPSTPVSKSPMVEQAVQTSSADNLNAKKLLPSKVTSGTQLNGRQAQPSSKTASDVVQPTPVHTQGQVNDENRRPPRRRSGNRRTRNRSRGQNRPTNVKENTIKFEGDFDFESANAQFNREELDKEFKKKLNFKDDKAEKGEEKDPAVMTQSEETPAEEDLLGPNCYYDKSKSFFDNISSELKTSSRRTTWAEERKLNTETFGVSGRFLRGRSSRGGFRGGRGNGTTRRNPTSHRAGTGRV", "length": 385, "header": "tr|A0A8C2MKW4-1|A0A8C2MKW4_CRIGR Computationally mapped isoform of Protein LSM14 homolog B isoform X5 OS=Cricetulus griseus OX=10029 GN=Lsm14b PE=3 SV=1 CANONICAL=A0A9J7G450-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G450-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450/entry#A0A9J7G450-1", "sequence": { "sequence": "MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRPAPPREEIYEYIIFRGSDIKDITVCEPPKAQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFRGMPPYGQLAASSLLSQQYAASLGLEKLVSPPASAAASSPSSSPSPQPVSELDMSSEPPQLTSKGAGFPSTPVSKSPMVEQAVQTSSADNLNAKKLLPSKVTSGTQLNGRQAQPSSKTASDVVQPTPVHTQGQVNDENRRPPRRRSGNRRTRNRSRGQNRPTNVKENTIKFEGDFDFESANAQFNREELDKEFKKKLNFKDDKAEKGEEKDPAVMTQSEETPAEEDLLGPNCYYDKSKSFFDNISSELKTSSRRTTWAEERKLNTETFGVSGRFLRGRSSRGGFRGGRGNGTTRRNPTSHRAGTGRV", "length": 424, "header": "tr|A0A9J7G450-1|A0A9J7G450_CRIGR Isoform 1 of Protein LSM14 homolog B isoform X2 OS=Cricetulus griseus OX=10029 GN=Lsm14b PE=3 SV=1 CANONICAL=A0A9J7G450-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450/entry#A0A9J7JKH6-1", "sequence": { "sequence": "MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRPAPPREEIYEYIIFRGSDIKDITVCEPPKAQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFRGMPPYGQLAASSLLSQQYAASLGLEKLVSPPASAAASSPSSSPSPQPVSELDMSSEPPQLTSKGAGFPSTPVSKSPMVEQAVQTSSADNLNAKKLLPSKVTSGTQLNGRQAQPSSKTASDVVQPTPVHTQGQVNDENRRPPRRRSGNRRTRNRSRGQNRPTNVKENTIKFEGDFDFESANAQFNREELDKEFKKKLNFKDDKAEKGEEKDPAVMTQSEETPAEEDLLGPNCYYDKSKSFFDNISSELKTSSRRTTWAEERKLNTETFGVSGRFLRGRSSRGGFRGGF", "length": 405, "header": "tr|A0A9J7JKH6-1|A0A9J7JKH6_CRIGR Computationally mapped isoform of Protein LSM14 homolog B isoform X3 OS=Cricetulus griseus OX=10029 GN=Lsm14b PE=3 SV=1 CANONICAL=A0A9J7G450-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTT9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450/entry#A0A9J7JTT9-1", "sequence": { "sequence": "MSGSSGTPYLGSKISLISKAQIRYEGILYTIDTDNSTVALAKVRSFGTEDRPTDRPAPPREEIYEYIIFRGSDIKDITVCEPPKAQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFRGMPPYGQLAASSLLSQQYAASLGLEKLVSPPASAAASSPSSSPSPQPVSELDMSSEPPQLTSKGAGFPSTPVSKSPMVEQAVQTSSADNLNAKKLLPSKVTSGTQLNGRQAQPSSKTASGNRRTRNRSRGQNRPTNVKENTIKFEGDFDFESANAQFNREELDKEFKKKLNFKDDKAEKGEEKDPAVMTQSEETPAEEDLLGPNCYYDKSKSFFDNISSELKTSSRRTTWAEERKLNTETFGVSGRFLRGRSSRGGFRGGRGNGTTRRNPTSHRAGTGRV", "length": 398, "header": "tr|A0A9J7JTT9-1|A0A9J7JTT9_CRIGR Computationally mapped isoform of Protein LSM14 homolog B isoform X4 OS=Cricetulus griseus OX=10029 GN=Lsm14b PE=3 SV=1 CANONICAL=A0A9J7G450-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 243, "start_aa": "Thr", "end_pos": 243, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr243", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769638", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769638", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "pmid": "" }, { "name": "ovarian follicle development", "id": "GO:0001541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001541", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "pmid": "" }, { "name": "membraneless organelle assembly", "id": "GO:0140694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140694", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "pmid": "" }, { "name": "meiotic cell cycle process involved in oocyte maturation", "id": "GO:1903537", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903537", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "pmid": "" }, { "name": "maternal mRNA clearance", "id": "GO:0141065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141065", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G450", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" }, { "id": "PS51512", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51512" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DFDF", "eco_id": "ECO_0000259", "start_pos": 280, "end_pos": 316, "start_aa": "Asn", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" }, { "id": "PRU00846", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00846" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "FFD box", "eco_id": "ECO_0000256", "start_pos": 349, "end_pos": 365, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" }, { "id": "PS51513", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51513" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FFD box profile", "eco_id": "ECO_0000259", "start_pos": 349, "end_pos": 365, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G450", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G450" }, { "id": "PS52002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sm", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 83, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G450", "database": "UniProtKB", "url": 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"mass": { "chemical_mass": 18355.0, "monoisotopic_mass": 18355.0 }, "refseq": { "ac": "XP_027274221", "name": "cytochrome c oxidase assembly protein COX16 homolog, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274221" }, "gene_names": [ { "name": "LOC100758725", "type": "recommended", "evidence": [ { "id": "A0A9J7G458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G458" } ] }, { "name": "LOC100758725", "type": "synonym", "evidence": [ { "id": "XP_027274221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274221" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A9J7G458", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G458/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase assembly protein COX16 homolog, mitochondrial", "type": "synonym", "evidence": [ { 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267469", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267469", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MF38", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MF38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G473", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G473", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G473-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G473-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"Thr", "end_pos": 175, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr175", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G473", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G473" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G473", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G473" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754663", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754663", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G473", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G473" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G473", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G473" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G473", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G473" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G473", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G473" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G473", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G473" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 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predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613827.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003501075.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501075" } ] }, { "annotation": "May play a role in p53/TP53-mediated apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G481", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481#function" }, { "database": "UniProtKB", "id": "ARBA00060301", "url": "https://www.uniprot.org/uniprotkb/ARBA00060301#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G481", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf385b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481", "locus": {} } ], "crossref": [ { "id": "A0A9J7G481", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G481", "database": "AlphaFoldDB", "categories": [] }, { "id": "100767842", "url": "https://www.ncbi.nlm.nih.gov/gene/100767842", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767842", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767842", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G481", "url": "https://www.orthodb.org/?gene=A0A9J7G481", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23067:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23067:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501075", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501075", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G481", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G481-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKCSLSPDNHCEDGSMNMATFLRGFEEKGLKNDRPGDQFNKEKKKILFSFCDVCNIQLNSAAQAQVHYDGKSHRKRVKQLSDGQPPPPAQGSGPLLASSCPCPGANTSTGSACHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKMVSSKDSAKANPSCSIRPITGDSSDKSDDKGKLKATSSTQPSGSEGGSFLLKSGTGPLPPAAITSPSKSTNGAPGSVAESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDLMKPLAPTFLSSPLAAAAVSSALSLPPRPSASLFQAAAIPPALLRPGHGPIRATPASILFAPY", "length": 495, "header": "tr|A0A9J7G481-1|A0A9J7G481_CRIGR Isoform 1 of Zinc finger protein 385B OS=Cricetulus griseus OX=10029 GN=Znf385b PE=4 SV=1 CANONICAL=A0A9J7G481-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G481-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481/entry#A0A9J7G481-1", "sequence": { "sequence": "MKCSLSPDNHCEDGSMNMATFLRGFEEKGLKNDRPGDQFNKEKKKILFSFCDVCNIQLNSAAQAQVHYDGKSHRKRVKQLSDGQPPPPAQGSGPLLASSCPCPGANTSTGSACHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDSSSAVGLFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSKHAKKVKALEATKNKPKMVSSKDSAKANPSCSIRPITGDSSDKSDDKGKLKATSSTQPSGSEGGSFLLKSGTGPLPPAAITSPSKSTNGAPGSVAESEEEKAKKLLYCSLCKVAVNSLSQLEAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNGSKGSGLQNKTFHCEICDVHVNSEIQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDLMKPLAPTFLSSPLAAAAVSSALSLPPRPSASLFQAAAIPPALLRPGHGPIRATPASILFAPY", "length": 495, "header": "tr|A0A9J7G481-1|A0A9J7G481_CRIGR Isoform 1 of Zinc finger protein 385B OS=Cricetulus griseus OX=10029 GN=Znf385b PE=4 SV=1 CANONICAL=A0A9J7G481-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 486, "start_aa": "Thr", "end_pos": 486, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr486", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G481", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G481", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767842", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767842", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G481", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G481", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G481", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G481", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G481" }, { "id": "PS00028", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 206, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 486 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 370, "end_pos": 372 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G482-1", "uniprot_ac": "A0A9J7G482", "uniprot_id": "A0A9J7G482_CRIGR", "mass": { "chemical_mass": 148157.0, "monoisotopic_mass": 148157.0 }, "refseq": { "ac": "XP_027275726", "name": "collagen alpha-1(XX) chain", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275726" }, "gene_names": [ { "name": "Col20a1", "type": "recommended", "evidence": [ { "id": "A0A9J7G482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482" } ] }, { "name": "Col20a1", "type": "synonym", "evidence": [ { "id": "XP_027275726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275726" } ] } ], "protein_names": [ { "name": "Collagen alpha-1(XX) chain", "type": "recommended", "evidence": [ { "id": "A0A9J7G482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482/entry#names_and_taxonomy" } ] }, { "name": "collagen alpha-1(XX) chain", "type": "synonym", "evidence": [ { "id": "XP_027275726", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275726" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275726" } ] }, { "annotation": "Probable collagen protein.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G482", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482#function" }, { "database": "UniProtKB", "id": "ARBA00056720", "url": "https://www.uniprot.org/uniprotkb/ARBA00056720#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G482", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Col20a1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482", "locus": {} } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01482", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01482", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759714", "url": "https://www.ncbi.nlm.nih.gov/gene/100759714", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759714", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759714", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G482", "url": 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G482", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G482-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1389, "header": "tr|A0A9J7G482-1|A0A9J7G482_CRIGR Isoform 1 of Collagen alpha-1(XX) chain OS=Cricetulus griseus OX=10029 GN=Col20a1 PE=4 SV=1 CANONICAL=A0A9J7G482-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G482-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482/entry#A0A9J7G482-1", "sequence": { "sequence": "MSPRGSYLHFCLWMLSATLALGQGQVSGRLRLAVLPEDQLQMKWREAEGSSLGYLVQVTPMAGDLEQELILTTKTPKATVGGLSPSKGYTLQIFELTDSGPVLLARREFVIEDLKSHSLSRGSRRLVGPTLDPTSFLLGASDPEKTLEPSIAFTSSKDRPILGDPQFHCTPPTPTDIIFLVDGSWSIGHRHFQKVKDFLASIITPFEIGPDKVQVGLTQYSGDPRTEWDLNSFHTKEQVLAAVHSLHYRGGNTFTGLALTHVLGQNLKPAAGARPEAAKVLILVTDGKSQDDVRTAARILKDQDIDVFVVGVKNADEAELKLLASQPLDITVHSVLDFPQLATLAALLSRLICQKIQGRGPGKDTQPHWPRGRLAEATPGQFLRPMRVCRLSQVVICPWICTWPPGGARCSCLLSCFLAFLLAPRLPFPTVKPAATTLALDPLPMPTRLDLTHITSSSVHLSWTPALYPPLKYLIVWQPSRGGAPKEVVVEGPVSSMELRNLTSNTEYLVSVLPVYENGFGKSLQGLATTAPLPPPGALTLASVTPRTLRLTWQPSAGATQYLVRYLLAASPGEEQRREVHVGQPEALLDGLEPGRDYEVSVQSLRGPEVSEVRSINARTTALGPPRHLSFSDVSYNSACVSWEAQRPVRLVKVSYVSSDGSHSGQAQVPGNTTSATLGPLSSSTKYTVRVTCFYFGGGSSMLTGHVTTKKAPSPSQLSVTELPGDAVKLSWVAAALSGVLVYQIKWMPLGEGKAHEISVPGTLDTAVLPGLMSHVEYEITILAYYRDGTRSDPVSLRYIPSSASRSPPSNLVLSSETPNSLQVSWTPPSGHVLHYRVNYALASGSGPEKWISVPGTRSHVVLPDLLSATKYRVLVSAVYGAGESVAVTATYRTAACPALHPDSSLSGFDLMVAFGLVAKEYASIRGVAMEPSALGAAPTFTLFKDAQLMRRASDIYPAALPPEHTIVFLVRLLPETPREAFALWQMMAEDFQPIVGVLLDAGRKSLTYFNHDPRAALQEVTFDLQDAKKIFFGSFHKVHVAVGHSKVRLYVDCRKVAERPIGDAGSPPTAGFITLGRLAKVRGPRSSSATFQLQMLQIVCSDSWADKDRCCELPALRDGETCPAFPSTCVCSSETPGPPGPQGPPGLPGRNGTPGQQGHPGPKGEPGPPGQTGPEGPGGQQGSPGTQGRTVQGPMGPPGVKGEKGDHGLPGLQGLSGQQGIPGKTGLQGPKGMRGLEGPAGLPGPPGPRGFQGLAGARGSNGERGPPGAVGPTGLPGSKGERGEKGEPQSLATIFQLVSQACESAIQTHVLRLNSFLHENARPPMPFMVETAKPSRPVSIEPPGSHNEALLPGDGGHVHHPEDQGEPEAISHISSPGLQESQTPEPLE", "length": 1389, "header": "tr|A0A9J7G482-1|A0A9J7G482_CRIGR Isoform 1 of Collagen alpha-1(XX) chain OS=Cricetulus griseus OX=10029 GN=Col20a1 PE=4 SV=1 CANONICAL=A0A9J7G482-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1070, "start_aa": "Thr", "end_pos": 1070, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1070", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1274, "start_aa": "Thr", "end_pos": 1274, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1274", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 378, "start_aa": "Thr", "end_pos": 378, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr378", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G482", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G482", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759714", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759714", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G482", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1152, "end_pos": 1154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 445, "end_pos": 534, "start_aa": "Met", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G482", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G482" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", 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"exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G497-1", "uniprot_ac": "A0A9J7G497", "uniprot_id": "A0A9J7G497_CRIGR", "mass": { "chemical_mass": 35259.0, "monoisotopic_mass": 35259.0 }, "refseq": { "ac": "XP_027276696", "name": "olfactory receptor 4F3/4F16/4F29-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276696" }, "gene_names": [ { "name": "LOC100774008", "type": "recommended", "evidence": [ { "id": "A0A9J7G497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G497" } ] }, { "name": "LOC100774008", "type": "synonym", "evidence": [ { "id": "XP_027276696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276696" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7G497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G497/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4F3/4F16/4F29-like", "type": "synonym", "evidence": [ { "id": "XP_027276696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276696" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G687-1", "uniprot_ac": "A0A9J7G687", "uniprot_id": "A0A9J7G687_CRIGR", "mass": { "chemical_mass": 40733.0, "monoisotopic_mass": 40733.0 }, "refseq": { "ac": "XP_027240263", "name": "transcription elongation factor A protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240263" }, "gene_names": [ { "name": "Tcea2", "type": "recommended", "evidence": [ { "id": "A0A9J7G687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687" } ] }, { "name": "Tcea2", "type": "synonym", "evidence": [ { "id": "XP_027240263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240263" } ] } ], "protein_names": [ { "name": "Transcription elongation factor", "type": "recommended", "evidence": [ { "id": "A0A9J7G687", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687/entry#names_and_taxonomy" } ] }, { "name": "transcription elongation factor A protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027240263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240263" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615430.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027240263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240263" } ] }, { "annotation": "Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G689", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G689#function" }, { "database": "UniProtKB", "id": "ARBA00025408", "url": "https://www.uniprot.org/uniprotkb/ARBA00025408#function" }, { "database": "UniProtKB", "id": "A0A9J7G4A9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A9#function" }, { "database": "UniProtKB", "id": "A0A9J7G4C9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C9#function" }, { "database": "UniProtKB", "id": "A0A9J7G687", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687#function" }, { "database": "UniProtKB", "id": "A0A9J7G8Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q2#function" }, { "database": "UniProtKB", "id": "A0A9J7K6W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6W4#function" }, { "database": "UniProtKB", "id": "A0A9J7H234", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H234#function" }, { "database": "UniProtKB", "id": "RU368078", "url": "https://www.uniprot.org/uniprotkb/RU368078#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G687", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tcea2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687", "locus": {} } ], "crossref": [ { "id": "A0A9J7G687", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G687", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00183", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00183", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13749", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13749", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768573", "url": "https://www.ncbi.nlm.nih.gov/gene/100768573", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001222", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001222", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006289", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006289", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768573", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768573", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G4A9", "url": "https://www.orthodb.org/?gene=A0A9J7G4A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G4C9", "url": "https://www.orthodb.org/?gene=A0A9J7G4C9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G687", "url": "https://www.orthodb.org/?gene=A0A9J7G687", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G8Q2", "url": "https://www.orthodb.org/?gene=A0A9J7G8Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H234", "url": "https://www.orthodb.org/?gene=A0A9J7H234", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11477", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11477", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11477:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11477:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07500", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07500", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027240263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240263", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G4A9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4C9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4C9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G687", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G687-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G689", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G689", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G689-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G689-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H234", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H234", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H234-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H234-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6W4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKEEEIARIARRLDKMVTRKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEELIALAKSLIKSWKKLLDVSDGKTRDQGRGTPLPTSSSKDTSGTTDLRLCLSSCKKPDPPRTLSTPRITTFPSVPITCDAVRNKCREMLTLALQTDHDHKAVGVDCEHLSAQIEECIFLDVGNTDMKYKNRVRSRISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCSKCKKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKVGGWAQNAHLQSCLSTYWTLSRNQGPLYPASLLGVSGMEPHACPISALGVMWGLGQIFSAFLQFC", "length": 367, "header": "tr|A0A9J7G687-1|A0A9J7G687_CRIGR Isoform 1 of Transcription elongation factor OS=Cricetulus griseus OX=10029 GN=Tcea2 PE=3 SV=1 CANONICAL=A0A9J7G687-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G4A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687/entry#A0A9J7G4A9-1", "sequence": { "sequence": "MGKEEEIARIARRLDKMVTRKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEELIALAKSLIKSWKKLLDVSDGKTRDQGRGTPLPTSSSKDTSGTTDLRLCLSSCKKPDPPRTLSTPRITTFPSVPITCDAVRNKCREMLTLALQTDHDHKAVGVDCEHLSAQIEECIFLDVGNTDMKYKNRVRSRISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCSKCKKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKFC", "length": 304, "header": "tr|A0A9J7G4A9-1|A0A9J7G687_CRIGR Computationally mapped isoform of Transcription elongation factor OS=Cricetulus griseus OX=10029 GN=Tcea2 PE=3 SV=1 CANONICAL=A0A9J7G687-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687/entry#A0A9J7G4C9-1", "sequence": { "sequence": "MGKEEEIARIARRLDKMVTRKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEELIALAKSLIKSWKKLLDVSDGKTRDQGRGTPLPTSSSKDTSGTTDLRLCLSSCKKPDPPRTLSTPRITTFPSVPITCDAVRNKCREMLTLALQTDHDHKAVGVDCEHLSAQIEECIFLDVGNTDMKYKNRVRSRISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCSKCKKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKGSCGALVRYSLPSCSSADPLY", "length": 323, "header": "tr|A0A9J7G4C9-1|A0A9J7G4C9_CRIGR Computationally mapped isoform of Transcription elongation factor OS=Cricetulus griseus OX=10029 GN=Tcea2 PE=3 SV=1 CANONICAL=A0A9J7G687-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G687-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687/entry#A0A9J7G687-1", "sequence": { "sequence": "MGKEEEIARIARRLDKMVTRKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEELIALAKSLIKSWKKLLDVSDGKTRDQGRGTPLPTSSSKDTSGTTDLRLCLSSCKKPDPPRTLSTPRITTFPSVPITCDAVRNKCREMLTLALQTDHDHKAVGVDCEHLSAQIEECIFLDVGNTDMKYKNRVRSRISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCSKCKKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKVGGWAQNAHLQSCLSTYWTLSRNQGPLYPASLLGVSGMEPHACPISALGVMWGLGQIFSAFLQFC", "length": 367, "header": "tr|A0A9J7G687-1|A0A9J7G687_CRIGR Isoform 1 of Transcription elongation factor OS=Cricetulus griseus OX=10029 GN=Tcea2 PE=3 SV=1 CANONICAL=A0A9J7G687-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G689-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687/entry#A0A9J7G689-1", "sequence": { "sequence": "MGKEEEIARIARRLDKMVTRKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEELIALAKSLIKSWKKLLDVSDGKTRDQGRGTPLPTSSSKDTSGTTDLSCKKPDPPRTLSTPRITTFPSVPITCDAVRNKCREMLTLALQTDHDHKAVGVDCEHLSAQIEECIFLDVGNTDMKYKNRVRSRISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCSKCKKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKVGGWAQNAHLQSCLSTYWTLSRNQGPLYPASLLGVSGMEPHACPISALGVMWGLGQIFSAFLQFC", "length": 362, "header": "tr|A0A9J7G689-1|A0A9J7G689_CRIGR Computationally mapped isoform of Transcription elongation factor OS=Cricetulus griseus OX=10029 GN=Tcea2 PE=3 SV=1 CANONICAL=A0A9J7G687-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687/entry#A0A9J7G8Q2-1", "sequence": { "sequence": "MGKEEEIARIARRLDKMVTRKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEELIALAKSLIKSWKKLLDVSDGKTRDQGRGTPLPTSSSKDTSGTTDLRLCLSSCKKPDPPRTLSTPRITTFPSVPITCDAVRNKCREMLTLALQTDHDHKAVGVDCEHLSAQIEECIFLDVGNTDMKYKNRVRSRISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCSKCKKKNCTYTQVQTRSSDEPMTTYVVCNECGNRWKIFSAFLQFC", "length": 311, "header": "tr|A0A9J7G8Q2-1|A0A9J7G8Q2_CRIGR Computationally mapped isoform of Transcription elongation factor OS=Cricetulus griseus OX=10029 GN=Tcea2 PE=3 SV=1 CANONICAL=A0A9J7G687-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H234-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G687/entry#A0A9J7H234-1", "sequence": { "sequence": "MGKEEEIARIARRLDKMVTRKSAEGAMDLLRELKAMPVTLHLLQSTRVGMSVNALRKQSSDEELIALAKSLIKSWKKLLDVSDGKTRDQGRGTPLPTSSSKDTSGTTDLRLCLSSCKKPDPPRTLSTPRITTFPSVPITCDAVRNKCREMLTLALQTDHDHKAVGVDCEHLSAQIEECIFLDVGNTDMKYKNRVRSRISNLKDAKNPGLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAIREHQMARTGGTQTDLFTCSKCKKKNCTYTQAKVTVIARRCRHLP", "length": 292, "header": 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003613838.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Dec 18, 2018 this sequence version replaced XP_003501252.2. 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"https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { 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"ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { 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[ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] } ] }, { "uniprot_ac": "A0A8C2N3U2", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] }, { "uniprot_ac": "A0A8C2N6L4", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] } ] }, { "uniprot_ac": "A0A8C2N756", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] } ] }, { "uniprot_ac": "A0A8C2N9X1", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] } ] }, { "uniprot_ac": "A0A8C2QDX9", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] } ] }, { "uniprot_ac": "A0A8C2QEB8", "gene_name": "Bub1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] } ] }, { "uniprot_ac": "A0A8C2QGY5", "gene_name": "Ttbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] } ] }, { "uniprot_ac": "A0A8C2QH69", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] } ] }, { "uniprot_ac": "A0A8C2QHF9", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] } ] }, { "uniprot_ac": "A0A8C2QHS8", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] } ] }, { "uniprot_ac": "A0A8C2QJ34", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] } ] }, { "uniprot_ac": "A0A8C2QJA4", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] } ] }, { "uniprot_ac": "A0A8C2QKP7", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKP7" } ] } ] }, { "uniprot_ac": "A0A8C2QL63", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": 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"ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { 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"activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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[ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] } ] }, { "uniprot_ac": "A0A9J7G969", "gene_name": "LOC100754771", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H0E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0E7" } ] } ] }, { "uniprot_ac": "A0A9J7H0W8", "gene_name": "Dapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H0W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0W8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H0W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0W8" } ] } ] }, { "uniprot_ac": "A0A9J7H1I4", "gene_name": "LOC100764243", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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{ "id": "A0A9J7H8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ] } ] }, { "uniprot_ac": "A0A9J7H8L4", "gene_name": "Irak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8L4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8L4" } ] } ] }, { "uniprot_ac": "A0A9J7H8U3", "gene_name": "Wnk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8U3", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J728" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J728" } ] } ] }, { "uniprot_ac": "A0A9J7JA07", "gene_name": "LOC100750629", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] } ] }, { "uniprot_ac": "A0A9J7JAB2", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] } ] }, { "uniprot_ac": "G3IN30", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] } ] }, { "uniprot_ac": "O55076", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] } ] }, { "uniprot_ac": "P25321", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] } ] }, { "uniprot_ac": "P50310", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "P50310", 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eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 30% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027272558.1. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4D5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4D5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"name": "interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003501069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501069" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613827.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501069" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4E8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prkra", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E8", "locus": {} } ], "crossref": [ { "id": "A0A9J7G4E8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G4E8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19889", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19889", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766102", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766102", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PEYEFEK", "url": "https://omabrowser.org/oma/group/PEYEFEK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G4E8", "url": "https://www.orthodb.org/?gene=A0A9J7G4E8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JQW9", "url": "https://www.orthodb.org/?gene=A0A9J7JQW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46205:SF2", "url": 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"MSHSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPSMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIAKEQGFSITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK", "length": 313, "header": "tr|A0A9J7G4E8-1|A0A9J7G4E8_CRIGR Isoform 1 of Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Cricetulus griseus OX=10029 GN=Prkra PE=3 SV=1 CANONICAL=A0A9J7G4E8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G4E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E8/entry#A0A9J7G4E8-1", "sequence": { "sequence": "MSHSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPSMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIAKEQGFSITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK", "length": 313, "header": "tr|A0A9J7G4E8-1|A0A9J7G4E8_CRIGR Isoform 1 of Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Cricetulus griseus OX=10029 GN=Prkra PE=3 SV=1 CANONICAL=A0A9J7G4E8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E8/entry#A0A9J7JQW9-1", "sequence": { "sequence": "MPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIAKEQGFSITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK", "length": 200, "header": "tr|A0A9J7JQW9-1|A0A9J7JQW9_CRIGR Computationally mapped isoform of Interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X2 OS=Cricetulus griseus OX=10029 GN=Prkra PE=3 SV=1 CANONICAL=A0A9J7G4E8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4E8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4E8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766102", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766102", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A5I9-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A", "gene_name": "PRKRA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSQSRHRAAAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK", "length": 313 }, "evidence": [ { "id": "A0A9J7G4E8", "url": "https://omabrowser.org/oma/group/A0A9J7G4E8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B0V3F8-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A homolog", "gene_name": "prkra", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPQRSQDKTPIQLLHEYGIKISSAPKYELIHADGDAHQPSFMFSVTIGEVTCKGRGSTKKAAKHEAAEAALKLLKRDSQIIDQRDNNGLSPEAGEASNPVGILQELAMQRVWCLPEYVVFMETGPGHMKEFTIACRLEGLEETGSGSSKKLARRAAAENMIAKLQSLSGSSEITWSPPSRVYVESLRNSTGEKVSLLKRTPLSLPNTDYIQMLLEISLELGFQVTYIDIDELTVNGQYQCLVELSTRPVTVCHGSGVTSSNAHNAAAHNALQYIKMVASKH", "length": 282 }, "evidence": [ { "id": "A0A9J7G4E8", "url": "https://omabrowser.org/oma/group/A0A9J7G4E8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O75569-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A", "gene_name": "PRKRA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK", "length": 313 }, "evidence": [ { "id": "A0A9J7G4E8", "url": "https://omabrowser.org/oma/group/A0A9J7G4E8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2HJ92-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A", "gene_name": "PRKRA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQSRHRAAAPPMEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNMVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLLSEIAKEQGFNITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCSSAQSDAAHNALQYLKIIAERK", "length": 313 }, "evidence": [ { "id": "A0A9J7G4E8", "url": "https://omabrowser.org/oma/group/A0A9J7G4E8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4V8C7-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A", "gene_name": "Prkra", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHSRHRAEAPPLQREDSGTFSLGKMITAKPGKTPIQVLHEYGTKTKNIPVYECERSDVQVHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIAKEQGFSITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK", "length": 313 }, "evidence": [ { "id": "A0A9J7G4E8", "url": "https://omabrowser.org/oma/group/A0A9J7G4E8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WTX2-1", "protein_name": "Interferon-inducible double-stranded RNA-dependent protein kinase activator A", "gene_name": "Prkra", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHSRHRAEAPPLQREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQVHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSLPNTDYIQLLSEIASEQGFNITYLDIEELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLKIIAERK", "length": 313 }, "evidence": [ { "id": "A0A9J7G4E8", "url": "https://omabrowser.org/oma/group/A0A9J7G4E8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4E8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4E8" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": 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This record is derived from a genomic sequence (NW_003613827.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003501071.1. 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"https://www.uniprot.org/uniprotkb/A0A9J7G4H1" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 150, "end_pos": 210, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"mass": { "chemical_mass": 12793.0, "monoisotopic_mass": 12793.0 }, "refseq": { "ac": "XP_003498385", "name": "homeobox protein Hox-D8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498385" }, "gene_names": [ { "name": "Hoxd8", "type": "recommended", "evidence": [ { "id": "A0A9J7G4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4I4" } ] }, { "name": "Hoxd8", "type": "synonym", "evidence": [ { "id": "XP_003498385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498385" } ] } ], "protein_names": [ { "name": "Homeobox protein Hox-D8", "type": "recommended", "evidence": [ { "id": "A0A9J7G4I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4I4/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Hox-D8", "type": "synonym", "evidence": [ { "id": "XP_003498385", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498385" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 356 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613688.1) and transcript sequence (IACG01089651.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003498385.3. 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Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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"monoisotopic_mass": 35609.0 }, "refseq": { "ac": "XP_027276866", "name": "olfactory receptor 4A5-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276866" }, "gene_names": [ { "name": "LOC100766317", "type": "recommended", "evidence": [ { "id": "A0A9J7G4J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J7" } ] }, { "name": "LOC100766317", "type": "synonym", "evidence": [ { "id": "XP_027276866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276866" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7G4J7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4A5-like", "type": "synonym", "evidence": [ { "id": "XP_027276866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276866" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276866" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4J7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766317", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J7", "locus": {} } ], "crossref": [ { "id": "A0A9J7G4J7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G4J7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766317", "url": "https://www.ncbi.nlm.nih.gov/gene/100766317", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766317", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766317", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G4J7", "url": "https://www.orthodb.org/?gene=A0A9J7G4J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276866", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G4J7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQHNNVTEFVLLGFTEDPAGKKALFVMFLLIYIVTMVGNLLIVVTVIVSPALGTPMYFFLASLSLMDAVYSTAISPRLIVDLLCDKKTIFFTACMSQLFIEHLFGGVDIVILVAMAYDRYVAICKPLHYLIIMNRRVCILFLGMAWAGGFAHAMFQVLVVCKLPFCGPNIIDHFICDTYPLLLLACTDTYSIGLSATVNNGAMCIVIFILLLLSYGIILRSLKNHSQEGRRKALFTCSSHITVVFLFFVPCIFMYARPVSSFPVDKSITVFYTVVTPMLNPLIYTLRNSEMKVSMEKLKQKILSPARIRLSSSCFIY", "length": 318, "header": "tr|A0A9J7G4J7-1|A0A9J7G4J7_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100766317 PE=3 SV=1 CANONICAL=A0A9J7G4J7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G4J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4J7/entry#A0A9J7G4J7-1", "sequence": { "sequence": "MGQHNNVTEFVLLGFTEDPAGKKALFVMFLLIYIVTMVGNLLIVVTVIVSPALGTPMYFFLASLSLMDAVYSTAISPRLIVDLLCDKKTIFFTACMSQLFIEHLFGGVDIVILVAMAYDRYVAICKPLHYLIIMNRRVCILFLGMAWAGGFAHAMFQVLVVCKLPFCGPNIIDHFICDTYPLLLLACTDTYSIGLSATVNNGAMCIVIFILLLLSYGIILRSLKNHSQEGRRKALFTCSSHITVVFLFFVPCIFMYARPVSSFPVDKSITVFYTVVTPMLNPLIYTLRNSEMKVSMEKLKQKILSPARIRLSSSCFIY", "length": 318, "header": "tr|A0A9J7G4J7-1|A0A9J7G4J7_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100766317 PE=3 SV=1 CANONICAL=A0A9J7G4J7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276899" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100762534", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3", "locus": {} } ], "crossref": [ { "id": "A0A9J7G4M3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G4M3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762534", "url": "https://www.ncbi.nlm.nih.gov/gene/100762534", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762534", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762534", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G4M3", "url": "https://www.orthodb.org/?gene=A0A9J7G4M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G4M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNQSFVTEFIFLGLSQNPKVQKIVSLVFLFVYIATVGGNMIIVVTIVCSPTLVDCPMYFFLAFLSLLDACFSSVITPKMVVDSLYEKKTISFEGCMIQLFAEHFLAAVEVIILTAMAYDRYVAICKPLHYSSIMNWKLCVMLMGIAWTGGFLHSIIQIIFTLQLPFCGPNVIDHFMCDLFPLLELACTDTYIFGLLVVANSGSICIIIFSILLVSYGVILFSLRSHSSEGRWKALSTCGSHIAVVVLFFVPCIFIYARPPSAFYFDKMVAIFYTILTPFLNPVIYTFRNKDMKSAMKKLWKRLIMVSDGK", "length": 311, "header": "tr|A0A9J7G4M3-1|A0A9J7G4M3_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100762534 PE=3 SV=1 CANONICAL=A0A9J7G4M3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G4M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3/entry#A0A9J7G4M3-1", "sequence": { "sequence": "MQNQSFVTEFIFLGLSQNPKVQKIVSLVFLFVYIATVGGNMIIVVTIVCSPTLVDCPMYFFLAFLSLLDACFSSVITPKMVVDSLYEKKTISFEGCMIQLFAEHFLAAVEVIILTAMAYDRYVAICKPLHYSSIMNWKLCVMLMGIAWTGGFLHSIIQIIFTLQLPFCGPNVIDHFMCDLFPLLELACTDTYIFGLLVVANSGSICIIIFSILLVSYGVILFSLRSHSSEGRWKALSTCGSHIAVVVLFFVPCIFIYARPPSAFYFDKMVAIFYTILTPFLNPVIYTFRNKDMKSAMKKLWKRLIMVSDGK", "length": 311, "header": "tr|A0A9J7G4M3-1|A0A9J7G4M3_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100762534 PE=3 SV=1 CANONICAL=A0A9J7G4M3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762534", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762534", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G4M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4M3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 286, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G4N4-1", "uniprot_ac": "A0A9J7G4N4", "uniprot_id": "A0A9J7G4N4_CRIGR", "mass": { "chemical_mass": 98906.0, "monoisotopic_mass": 98906.0 }, "refseq": { "ac": "XP_027276255", "name": "LOW QUALITY PROTEIN: transcription factor Sp3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276255" }, "gene_names": [ { "name": "Sp3", "type": "recommended", "evidence": [ { "id": "A0A9J7G4N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4N4" } ] }, { "name": "Sp3", "type": "synonym", "evidence": [ { "id": "XP_027276255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276255" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: transcription factor Sp3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027276255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276255" }, { "id": "A0A9J7G4N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4N4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 21% of CDS bases frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276255" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4N4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sp3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4N4", "locus": {} } ], "crossref": [ { "id": "A0A9J7G4N4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G4N4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22537", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22537", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774926", "url": "https://www.ncbi.nlm.nih.gov/gene/100774926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774926", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G4N4", "url": "https://www.orthodb.org/?gene=A0A9J7G4N4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276255", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G4N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4N4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTASPGPPPPPPAPGPECATECLWRRKAALPFASLPPPASSQPAASHERPALQPQQRRSARRVGRAASPPGSAIPLCAGAGRRAGVCELLTLPKSVKNKRKGADVDSGGWRRRAMERFCRQQAQQQQQHSSHGNGRGGRLAGGPVCKCARPPGWEPGGGEARRAAVRRGAAERAERRERRRRPGGGGGGGGERGPGWPARSGAEDTQPSPLALLAATCSKIGPPSPGDDEREAAAAAGAARRAAPPAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPGAATSSGQYVLPLQNLQNQQIFSVAPGSDSSNGTVSNVQYQVIPQIQSTDAQQVQIGFTGSSDNGGINQENSQIQIIPGSNQTLLASGTPPANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVPLGLPGNITFVPINSVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDVNETNADTDLFVPTSSSSQLPVTIDSTGILQQNTNSLTTSSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQDSQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGALTSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKKVIHSSSTVLASVEAGRDDTLITAGGTTLILANIQQGSVSGIGTVNTSATSNQDILTNTEIPLQLVTVSGNETME", "length": 938, "header": "tr|A0A9J7G4N4-1|A0A9J7G4N4_CRIGR Isoform 1 of LOW QUALITY PROTEIN: transcription factor Sp3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Sp3 PE=3 SV=1 CANONICAL=A0A9J7G4N4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G4N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4N4/entry#A0A9J7G4N4-1", "sequence": { "sequence": "MTASPGPPPPPPAPGPECATECLWRRKAALPFASLPPPASSQPAASHERPALQPQQRRSARRVGRAASPPGSAIPLCAGAGRRAGVCELLTLPKSVKNKRKGADVDSGGWRRRAMERFCRQQAQQQQQHSSHGNGRGGRLAGGPVCKCARPPGWEPGGGEARRAAVRRGAAERAERRERRRRPGGGGGGGGERGPGWPARSGAEDTQPSPLALLAATCSKIGPPSPGDDEREAAAAAGAARRAAPPAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPGAATSSGQYVLPLQNLQNQQIFSVAPGSDSSNGTVSNVQYQVIPQIQSTDAQQVQIGFTGSSDNGGINQENSQIQIIPGSNQTLLASGTPPANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVPLGLPGNITFVPINSVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDVNETNADTDLFVPTSSSSQLPVTIDSTGILQQNTNSLTTSSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQDSQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNTAAQQITLTPVQTLTLGQVAAGGALTSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKKVIHSSSTVLASVEAGRDDTLITAGGTTLILANIQQGSVSGIGTVNTSATSNQDILTNTEIPLQLVTVSGNETME", "length": 938, "header": "tr|A0A9J7G4N4-1|A0A9J7G4N4_CRIGR 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{ "name": "M-type receptor", "type": "synonym", "evidence": [ { "id": "A0A9J7G4S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S0/entry#names_and_taxonomy" } ] }, { "name": "secretory phospholipase A2 receptor", "type": "synonym", "evidence": [ { "id": "XP_027276146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276146" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276146", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276146" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4S0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pla2r1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S0", "locus": {} } ], "crossref": [ { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00062", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00062", "database": "CDD", 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF01843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276402", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276402", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G4S1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSGERKEGGSPRFGKLHLPVGLWINSPRKQLAKLGRRWPSAASVKSSSSDTGSRSSEPLPPPPPHVELRRVGAVKAAGGASGSRAKRISQLFRGSGAGGAGGPGTPGGAQRWASEKKLPELAAGVAPEPPLPTRAAVPPGVLKIFAAGLASGANYKSVLATERSTARELVAEALERYGLAGGRGAGDGGCVDAYALCDALGRPAAGVGGGEWRAEHLRVLADAERPLLVQDLWRARPGWARRFELRGREEARRLEQEVFGAADGDGTNAPSWRTQKNRSRAASGGAALASPGPGSGSGTPTGSGGKERSENLSLRRSVSELSLQGRRRRQQERRQQALSMAPGAADTQMVPTDPGDFDQLTQCLIQAPSNRPYFLLLQGYQDAQDFVVYVMTREQHVFGRGGPSSSRGGSPAPYVDTFLNAPDILPRHCTVRAGPEPPAMVRPSRGAPVTHNGCLLLREAELHPGDLLGLGEHFLFMYKDPRAGGSGPARPPWLPSRPGAAPPGPGWAFSCRLCGRGLQERGEALAAYLDGREPVLRFRPREEEALLGEIVRAAASGAGDLPPLGPATLLALCVQHSARELELGHLPRLLGRLARLIKEAVWEKIKEIGDRQPENHPEGVPEEPLTPEAVSVELRPLILWMANTTELLSFVQEKVLEMEKEADQEGLSSDPQLCNDLELCDEALALLDEVIMCTFQQSVYYLTKTLYSTLPALLDSNPFTAGAELPGPGAELEAMPPGLRPTLGVFQAALELTSQCELHPDLVSQTFGYLFFFSNASLLNSLMERGQGRPFYQWSRAVQIRTNLDLVLDWLQGAGLGDIATEFFRKLSIAVNLLCVPRTSLLKASWSSLRTDYPTLTPAQLHHLLSHYQLGPGRGPPPAWDPPPAERDAVDTGDIFESFSSHPPLILPLGSSRLRLTGLVTDDALHRELRRLRRLLWDLEQQELPANHRHGPPVAASP", "length": 959, "header": "tr|A0A9J7G4S1-1|A0A9J7G4S1_CRIGR Isoform 1 of Ras-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Rasip1 PE=4 SV=1 CANONICAL=A0A9J7G4S1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G4S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1/entry#A0A9J7G4S1-1", "sequence": { "sequence": "MLSGERKEGGSPRFGKLHLPVGLWINSPRKQLAKLGRRWPSAASVKSSSSDTGSRSSEPLPPPPPHVELRRVGAVKAAGGASGSRAKRISQLFRGSGAGGAGGPGTPGGAQRWASEKKLPELAAGVAPEPPLPTRAAVPPGVLKIFAAGLASGANYKSVLATERSTARELVAEALERYGLAGGRGAGDGGCVDAYALCDALGRPAAGVGGGEWRAEHLRVLADAERPLLVQDLWRARPGWARRFELRGREEARRLEQEVFGAADGDGTNAPSWRTQKNRSRAASGGAALASPGPGSGSGTPTGSGGKERSENLSLRRSVSELSLQGRRRRQQERRQQALSMAPGAADTQMVPTDPGDFDQLTQCLIQAPSNRPYFLLLQGYQDAQDFVVYVMTREQHVFGRGGPSSSRGGSPAPYVDTFLNAPDILPRHCTVRAGPEPPAMVRPSRGAPVTHNGCLLLREAELHPGDLLGLGEHFLFMYKDPRAGGSGPARPPWLPSRPGAAPPGPGWAFSCRLCGRGLQERGEALAAYLDGREPVLRFRPREEEALLGEIVRAAASGAGDLPPLGPATLLALCVQHSARELELGHLPRLLGRLARLIKEAVWEKIKEIGDRQPENHPEGVPEEPLTPEAVSVELRPLILWMANTTELLSFVQEKVLEMEKEADQEGLSSDPQLCNDLELCDEALALLDEVIMCTFQQSVYYLTKTLYSTLPALLDSNPFTAGAELPGPGAELEAMPPGLRPTLGVFQAALELTSQCELHPDLVSQTFGYLFFFSNASLLNSLMERGQGRPFYQWSRAVQIRTNLDLVLDWLQGAGLGDIATEFFRKLSIAVNLLCVPRTSLLKASWSSLRTDYPTLTPAQLHHLLSHYQLGPGRGPPPAWDPPPAERDAVDTGDIFESFSSHPPLILPLGSSRLRLTGLVTDDALHRELRRLRRLLWDLEQQELPANHRHGPPVAASP", "length": 959, "header": "tr|A0A9J7G4S1-1|A0A9J7G4S1_CRIGR Isoform 1 of Ras-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Rasip1 PE=4 SV=1 CANONICAL=A0A9J7G4S1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 106, "start_aa": "Thr", "end_pos": 106, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr106", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4S1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4S1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751764", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751764", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4S1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4S1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4S1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4S1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4S1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" } ], "pmid": "" }, { "name": "Golgi stack", "id": "GO:0005795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4S1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4S1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G4S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" }, { "id": "PS51126", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51126" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dilute", "eco_id": "ECO_0000259", "start_pos": 592, "end_pos": 893, "start_aa": "Gly", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G4S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S1" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 251, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 106 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 278, "end_pos": 280 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 644, "end_pos": 646 }, { "start_pos": 776, "end_pos": 778 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", 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"A0A9J7G4S7", "uniprot_id": "A0A9J7G4S7_CRIGR", "mass": { "chemical_mass": 35172.0, "monoisotopic_mass": 35172.0 }, "refseq": { "ac": "XP_027276977", "name": "olfactory receptor 8H1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276977" }, "gene_names": [ { "name": "LOC100757037", "type": "recommended", "evidence": [ { "id": "A0A9J7G4S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S7" } ] }, { "name": "LOC100757037", "type": "synonym", "evidence": [ { "id": "XP_027276977", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276977" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7G4S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4S7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 8H1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027276977", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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"phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614844.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007649008.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007649008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649008" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100756768", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3", "locus": {} } ], "crossref": [ { "id": "A0A9J7G4X3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G4X3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756768", "url": "https://www.ncbi.nlm.nih.gov/gene/100756768", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756768", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756768", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G4X3", "url": "https://www.orthodb.org/?gene=A0A9J7G4X3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007649008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649008", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G4X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGHPHPWKWTVATLVATLVLGVSEPVLAEDVSSCGDPSGNRPSGTNRDLSRESESGEDTRSDSSSRIINGSDCEKDAQPWQGALLLGPNKLYCGAVLINPQWLLTAAHCRKPVYRIRLGHHSMSPVYESGQQMFQGIKSIPHPGYSHPGHSNDLMLIKMNRKIRDSHSVKPIKIASDCPAQGTRCLVSGWGTTSSSHNNFPKVLQCLNITVLSEEKCKNSYPGQIDKSMFCAGDEEGRDSCQGDSGGPVICNGQLQGLVSWGDFPCAQRNRPGVYTKLCEFSKWIDDTIKSNS", "length": 294, "header": "tr|A0A9J7G4X3-1|A0A9J7G4X3_CRIGR Isoform 1 of Kallikrein-5 OS=Cricetulus griseus OX=10029 GN=LOC100756768 PE=3 SV=1 CANONICAL=A0A9J7G4X3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G4X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3/entry#A0A9J7G4X3-1", "sequence": { "sequence": "MAGHPHPWKWTVATLVATLVLGVSEPVLAEDVSSCGDPSGNRPSGTNRDLSRESESGEDTRSDSSSRIINGSDCEKDAQPWQGALLLGPNKLYCGAVLINPQWLLTAAHCRKPVYRIRLGHHSMSPVYESGQQMFQGIKSIPHPGYSHPGHSNDLMLIKMNRKIRDSHSVKPIKIASDCPAQGTRCLVSGWGTTSSSHNNFPKVLQCLNITVLSEEKCKNSYPGQIDKSMFCAGDEEGRDSCQGDSGGPVICNGQLQGLVSWGDFPCAQRNRPGVYTKLCEFSKWIDDTIKSNS", "length": 294, "header": "tr|A0A9J7G4X3-1|A0A9J7G4X3_CRIGR Isoform 1 of Kallikrein-5 OS=Cricetulus griseus OX=10029 GN=LOC100756768 PE=3 SV=1 CANONICAL=A0A9J7G4X3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756768", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756768", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3" } ], "pmid": "" }, { "name": "extracellular matrix disassembly", "id": "GO:0022617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022617", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3" } ], "pmid": "" }, { "name": "amelogenesis", "id": "GO:0097186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097186", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3" } ], "pmid": "" }, { "name": "positive regulation of antibacterial peptide production", "id": "GO:0002803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002803", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "secretory granule", "id": "GO:0030141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030141", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G4X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X3" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 291, "start_aa": "Ile", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G4X8-1", "uniprot_ac": "A0A9J7G4X8", "uniprot_id": "A0A9J7G4X8_CRIGR", "mass": { "chemical_mass": 184263.0, "monoisotopic_mass": 184263.0 }, "refseq": { "ac": "XP_027276266", "name": "methyl-CpG-binding domain protein 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276266" }, "gene_names": [ { "name": "Mbd5", "type": "recommended", "evidence": [ { "id": "A0A9J7G4X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8" } ] }, { "name": "Mbd5", "type": "synonym", "evidence": [ { "id": "XP_027276266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276266" } ] } ], "protein_names": [ { "name": "Methyl-CpG-binding domain protein 5", "type": "recommended", "evidence": [ { "id": "A0A9J7G4X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8/entry#names_and_taxonomy" } ] }, { "name": "Methyl-CpG-binding protein MBD5", "type": "synonym", "evidence": [ { "id": "A0A9J7G4X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8/entry#names_and_taxonomy" } ] }, { "name": "methyl-CpG-binding domain protein 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027276266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276266" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276266", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276266" } ] }, { "annotation": "Non-catalytic component of the polycomb repressive deubiquitinase (PR-DUB) complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-120' (H2AK119ub1). Important for stability of PR-DUB components and stimulating its ubiquitinase activity. As part of the PR-DUB complex, associates with chromatin enriched in histone marks H3K4me1, H3K4me3, and H3K27Ac, but not in H3K27me3. The PR-DUB complex is an epigenetic regulator of gene expression, including genes involved in cell growth and survivability. MBD5 and MBD6 containing complexes associate with distinct chromatin regions enriched in genes involved in different pathways. Heterochromatin recruitment is not mediated by DNA methylation. The PR-DUB complex is an epigenetic regulator of gene expression, including genes involved in development, cell communication, signaling, cell proliferation and cell viability.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8#function" }, { "database": "UniProtKB", "id": "ARBA00057571", "url": "https://www.uniprot.org/uniprotkb/ARBA00057571#function" }, { "database": "UniProtKB", "id": "A0A9J7JU91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU91#function" }, { "database": "UniProtKB", "id": "A0A9J7KAY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mbd5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8", "locus": {} } ], "crossref": [ { "id": "cd20141", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20141", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750416", "url": "https://www.ncbi.nlm.nih.gov/gene/100750416", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750416", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750416", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G4X8", "url": "https://www.orthodb.org/?gene=A0A9J7G4X8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16112:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16112:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_027276266", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276266", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G4X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JU91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JU91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGGKECDGGDKEGGLPAIQVPVGWQRRVDHSGVLYISPSGSLLSCLEQVKTYLLTDGTCKCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPHPSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMTGSSNAMGRLYVQDLPGNQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPRTDPLGSPDVFTRNNPSFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLSPTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGILDPIPSKPVNQNPIIINPTSFHSNVHSQVPVMNVSMPPAVVPLPSNLPLPTVKPGHMNHGSHVQRIQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQATCSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKEIPNPLIAGMSNVLNTPSSAAFPTASAGNGSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSSSSNNSGAVASSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDSLRKRKQPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNSTPGCGGSNTALPCSANQLHFPDPNMNSSVLQNSLTQSIPLRGEAVHCHNANTNFVHSNSPVPNHHLAGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISASSTPVIPNSVVSSYNQTSSEAGGPSLPSSIAIAGSNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHFPSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGFLNPNVNAALAFLSSDMDGQVLQPVHFQLLAALLQNQAQAAAMLPLTSLNLTISDLLQQQNTPLPLLTQMTAPSDRLPSNQSDNSRAETHLTSPLGNPLPSFTGSDTTFNPLLLPAVTGASGLMALNPQLLGGVLNSASANTANHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVVSMAETLLNISNNAGNPPGPAKLNSNSVVPQLLNPLLGTGLLGDISSINNSLNNHQLSHLQSLLNSNQMFPPSQQQQQHLLQGHQNLQAFQGQPTVPCPANNNPMACLFQNFQVRMQGDAALLNKRISTQPGLTALPENPNTALPHFQDTPCELQPRIDPSFGQPVKDGLVMGGQGDASVDAIYKAVVDAASKGMQVVITTAVNSTTQISPVPALSAMSAFTASIGDPLNLSSAVSAVIHGRSMGGVDHDGRLRNARGARLPKSIDHGKHSSEGDGFEYFKSASCHTSRKQWDGEQSPRGERNRWKYEEFLEHPGHVHSSPCHERPNNVSTLPFLAGEQHPLLLPPRNCQGDKILEENFRYNNYKRTMMSFKERLESTVERCTHINGNRPRQSRGFGELLGTAKQDLVLEGQSPGSSNSLESSLVKDYIHYNGDFNAKSINGCVPSPSDAKSISSEDDLRNPDSPSSHELIHYRPRTFNVGDLVWGQIKGLTSWPGKFIREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRRKISR", "length": 1733, "header": "tr|A0A9J7G4X8-1|A0A9J7G4X8_CRIGR Isoform 1 of Methyl-CpG-binding domain protein 5 OS=Cricetulus griseus OX=10029 GN=Mbd5 PE=4 SV=1 CANONICAL=A0A9J7G4X8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G4X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8/entry#A0A9J7G4X8-1", "sequence": { "sequence": "MNGGKECDGGDKEGGLPAIQVPVGWQRRVDHSGVLYISPSGSLLSCLEQVKTYLLTDGTCKCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPHPSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMTGSSNAMGRLYVQDLPGNQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPRTDPLGSPDVFTRNNPSFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLSPTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGILDPIPSKPVNQNPIIINPTSFHSNVHSQVPVMNVSMPPAVVPLPSNLPLPTVKPGHMNHGSHVQRIQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQATCSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKEIPNPLIAGMSNVLNTPSSAAFPTASAGNGSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSSSSNNSGAVASSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDSLRKRKQPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNSTPGCGGSNTALPCSANQLHFPDPNMNSSVLQNSLTQSIPLRGEAVHCHNANTNFVHSNSPVPNHHLAGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISASSTPVIPNSVVSSYNQTSSEAGGPSLPSSIAIAGSNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHFPSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGFLNPNVNAALAFLSSDMDGQVLQPVHFQLLAALLQNQAQAAAMLPLTSLNLTISDLLQQQNTPLPLLTQMTAPSDRLPSNQSDNSRAETHLTSPLGNPLPSFTGSDTTFNPLLLPAVTGASGLMALNPQLLGGVLNSASANTANHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVVSMAETLLNISNNAGNPPGPAKLNSNSVVPQLLNPLLGTGLLGDISSINNSLNNHQLSHLQSLLNSNQMFPPSQQQQQHLLQGHQNLQAFQGQPTVPCPANNNPMACLFQNFQVRMQGDAALLNKRISTQPGLTALPENPNTALPHFQDTPCELQPRIDPSFGQPVKDGLVMGGQGDASVDAIYKAVVDAASKGMQVVITTAVNSTTQISPVPALSAMSAFTASIGDPLNLSSAVSAVIHGRSMGGVDHDGRLRNARGARLPKSIDHGKHSSEGDGFEYFKSASCHTSRKQWDGEQSPRGERNRWKYEEFLEHPGHVHSSPCHERPNNVSTLPFLAGEQHPLLLPPRNCQGDKILEENFRYNNYKRTMMSFKERLESTVERCTHINGNRPRQSRGFGELLGTAKQDLVLEGQSPGSSNSLESSLVKDYIHYNGDFNAKSINGCVPSPSDAKSISSEDDLRNPDSPSSHELIHYRPRTFNVGDLVWGQIKGLTSWPGKFIREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRRKISR", "length": 1733, "header": "tr|A0A9J7G4X8-1|A0A9J7G4X8_CRIGR Isoform 1 of Methyl-CpG-binding domain protein 5 OS=Cricetulus griseus OX=10029 GN=Mbd5 PE=4 SV=1 CANONICAL=A0A9J7G4X8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JU91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8/entry#A0A9J7JU91-1", "sequence": { "sequence": "MNGGKECDGGDKEGGLPAIQVPVGWQRRVDHSGVLYISPSGSLLSCLEQVKTYLLTDGTCKCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPHPSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMTGSSNAMGRLYVQDLPGNQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPRTDPLGSPDVFTRNNPSFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLSPTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGILDPIPSKPVNQNPIIINPTSFHSNVHSQVPVMNVSMPPAVVPLPSNLPLPTVKPGHMNHGSHVQRIQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQATCSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKEIPNPLIAGMSNVLNTPSSAAFPTASAGNGSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSSSSNNSGAVASSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDSLRKRKQPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNSTPGCGGSNTALPCSANQLHFPDPNMNSSVLQNSLTQSIPLRGEAVHCHNANTNFVHSNSPVPNHHLAGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISASSTPVIPNSVVSSYNQTSSEAGGPSLPSSIAIAGSNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHFPSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGDISSINNSLNNHQLSHLQSLLNSNQMFPPSQQQQQHLLQGHQNLQAFQGQPTVPCPANNNPMACLFQNFQVRMQGDAALLNKRISTQPGLTALPENPNTALPHFQDTPCELQPRIDPSFGQPVKDGLVMGGQGDASVDAIYKAVVDAASKGMQVVITTAVNSTTQISPVPALSAMSAFTASIGDPLNLSSAVSAVIHGRSMGGVDHDGRLRNARGARLPKSIDHGKHSSEGDGFEYFKSASCHTSRKQWDGEQSPRGERNRWKYEEFLEHPGHVHSSPCHERPNNVSTLPFLAGEQHPLLLPPRNCQGDKILEENFRYNNYKRTMMSFKERLESTVERCTHINGNRPRQSRGFGELLGTAKQDLVLEGQSPGSSNSLESSLVKDYIHYNGDFNAKSINGCVPSPSDAKSISSEDDLRNPDSPSSHELIHYRPRTFNVGDLVWGQIKGLTSWPGKFIREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKRNRKSGKLNNHLEAAIHEAMSELDKMSGTVHQIPQGDRQMRPPKPKRRKISR", "length": 1500, "header": "tr|A0A9J7JU91-1|A0A9J7JU91_CRIGR Computationally mapped isoform of Methyl-CpG-binding domain protein 5 OS=Cricetulus griseus OX=10029 GN=Mbd5 PE=4 SV=1 CANONICAL=A0A9J7G4X8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8/entry#A0A9J7KAY8-1", "sequence": { "sequence": "MNGGKECDGGDKEGGLPAIQVPVGWQRRVDHSGVLYISPSGSLLSCLEQVKTYLLTDGTCKCGLECPLILPKVFNFDPGAAVKQRTAEDVKADEDVTKLCIHKRKIIAVATLHKSMEAPHPSLVLTSPGGGTNATPVVPSRAATPRSVRNKSHEGITNSVMPECKNPFKLMTGSSNAMGRLYVQDLPGNQQQELHPVYPRQRLGSSEHGQKSPFRGSHGGLPSPASSGSQIYGDGSISPRTDPLGSPDVFTRNNPSFHGAPNSSPIHLNRTPLSPPSVMLHGSPVQSSCAMAGRTNIPLSPTLTTKSPVMKKPMCNFSTNMEIPRAMFHHKPPQGPPPPPPPSCALQKKPLTSEKDPLGILDPIPSKPVNQNPIIINPTSFHSNVHSQVPVMNVSMPPAVVPLPSNLPLPTVKPGHMNHGSHVQRIQHSASTSLSPSPVTSPVHMMGTGIGRIEASPQRSRSSSTSSDHGNFMMPPVGPQATCSGIKVPPRSPRSTIGSPRPSMPSSPSTKSDGHHQYKEIPNPLIAGMSNVLNTPSSAAFPTASAGNGSVKSQPGLLGMPLNQILNQHNAASFPASSLLSAAAKAQLANQNKLAGNNSSSSNNSGAVASSGNTEGHSTLNTMFPPTANMLLPTGEGQSGRAALRDKLMSQQKDSLRKRKQPPTTVLSLLRQSQMDSSAVPKPGPDLLRKQGQGSFPISSMSQLLQSMSCQSSHLSSNSTPGCGGSNTALPCSANQLHFPDPNMNSSVLQNSLTQSIPLRGEAVHCHNANTNFVHSNSPVPNHHLAGLINQIQASGNCGMLSQSGMALGNSLHPNPPQSRISASSTPVIPNSVVSSYNQTSSEAGGPSLPSSIAIAGSNHPAITKTTSVLQDGVIVTTAAGNPLQSQLPIGSDFPFVGQEHALHFPSNSTSNNHLPHPLNPSLLSSLPISLPVNQQHLLNQNLLNILQPSAGEGKSEINLHPLGFLNPNVNAALAFLSSDMDGQVLQPVHFQLLAALLQNQAQAAAMLPLTSLNLTISDLLQQQNTPLPLLTQMTAPSDRLPSNQSDNSRAETHLTSPLGNPLPSFTGSDTTFNPLLLPAVTGASGLMALNPQLLGGVLNSASANTANHPEVSIATSSQATTTTTTTSSAVAALTVSTLGGTAVVSMAETLLNISNNAGNPPGPAKLNSNSVVPQLLNPLLGTGLLGDISSINNSLNNHQLSHLQSLLNSNQMFPPSQQQQQHLLQGHQNLQAFQGQPTVPCPANNNPMACLFQNFQVRMQGDAALLNKRISTQPGLTALPENPNTALPHFQDTPCELQPRIDPSFGQPVKDGLVMGGQGDASVDAIYKAVVDAASKGMQVVITTAVNSTTQISPVPALSAMSAFTASIGDPLNLSSAVSAVIHGRSMGGVDHDGRLRNARGARLPKSIDHGKHSSEGDGFEYFKSASCHTSRKQWDGEQSPRGERNRWKYEEFLEHPGHVHSSPCHERPNNVSTLPFLAGEQHPLLLPPRNCQGDKILEENFRYNNYKRTMMSFKERLESTVERCTHINGNRPRQSRGFGELLGTAKQDLVLEGQSPGSSNSLESSLVKDYIHYNGDFNAKSINGCVPSPSDAKSISSEDDLRNPDSPSSHELIHYRPRTFNVGDLVWGQIKGLTSWPGKFIREDDVHNSCQQSPEEGKVEPEKLKTLTEGLEAYSRVRKRNRKYYSSLIFLIRGP", "length": 1697, "header": "tr|A0A9J7KAY8-1|A0A9J7KAY8_CRIGR Computationally mapped isoform of Methyl-CpG-binding domain protein 5 OS=Cricetulus griseus OX=10029 GN=Mbd5 PE=4 SV=1 CANONICAL=A0A9J7G4X8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 720, "start_aa": "Thr", "end_pos": 720, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr720", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750416", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750416", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8" } ], "pmid": "" }, { "name": "chromocenter", "id": "GO:0010369", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010369", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4X8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of multicellular organismal process", "id": "GO:0051239", "url": 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"evidence": [ { "id": "A0A9J7G4Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0/entry#names_and_taxonomy" } ] }, { "name": "Natural killer cell protein 7", "type": "synonym", "evidence": [ { "id": "A0A9J7G4Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0/entry#names_and_taxonomy" } ] }, { "name": "protein NKG7", "type": "synonym", "evidence": [ { "id": "XP_027276313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276313" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276313" } ] }, { "annotation": "Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases. Essential for cytotoxic degranulation of natural killer (NK) cells and CD8(+) T-cells and for the activation of CD4(+) T-cells following infection. Plays a critical role in CD8(+) T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules. Contributes to NK cell-mediated control of cancer metastasis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0#function" }, { "database": "UniProtKB", "id": "ARBA00059714", "url": "https://www.uniprot.org/uniprotkb/ARBA00059714#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nkg7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0", "locus": {} } ], "crossref": [ { "id": "A0A9J7G4Z0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G4Z0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100752474", "url": "https://www.ncbi.nlm.nih.gov/gene/100752474", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752474", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752474", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G4Z0", "url": "https://www.orthodb.org/?gene=A0A9J7G4Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G4Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPCRSLALLAGSLGLTSSLIALSTDFWIVATGPKFSSHSGLWPTTHGIQVAGYIHVTQSFCILAALWSLVSMVFLILSYSPALSVPGRGPLVSTVMSFAAALSVIVAMAVYTSSRWSQTPSPQVQTSFAWSFYLGWVSSVLFLCAGCLSLGAHCRTHRAGYETL", "length": 165, "header": "tr|A0A9J7G4Z0-1|A0A9J7G4Z0_CRIGR Isoform 1 of Protein NKG7 OS=Cricetulus griseus OX=10029 GN=Nkg7 PE=3 SV=1 CANONICAL=A0A9J7G4Z0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G4Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0/entry#A0A9J7G4Z0-1", "sequence": { "sequence": "MEPCRSLALLAGSLGLTSSLIALSTDFWIVATGPKFSSHSGLWPTTHGIQVAGYIHVTQSFCILAALWSLVSMVFLILSYSPALSVPGRGPLVSTVMSFAAALSVIVAMAVYTSSRWSQTPSPQVQTSFAWSFYLGWVSSVLFLCAGCLSLGAHCRTHRAGYETL", "length": 165, "header": "tr|A0A9J7G4Z0-1|A0A9J7G4Z0_CRIGR Isoform 1 of Protein NKG7 OS=Cricetulus griseus OX=10029 GN=Nkg7 PE=3 SV=1 CANONICAL=A0A9J7G4Z0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A9J7G4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0" } ], "pmid": "" }, { "name": "killing of cells of another organism", "id": "GO:0031640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031640", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0" } ], "pmid": "" }, { "name": "defense response to protozoan", "id": "GO:0042832", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042832", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G4Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4Z0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": 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Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276416" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Plekha4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z6", "locus": {} } ], "crossref": [ { "id": "cd13248", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13248", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752943", "url": "https://www.ncbi.nlm.nih.gov/gene/100752943", "database": "GeneID", "categories": [ "Genome 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276387" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G520", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G520" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sphk2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G520", "locus": {} } ], "crossref": [ { "id": "100774790", "url": "https://www.ncbi.nlm.nih.gov/gene/100774790", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001206", "database": "InterPro", "categories": [ "Protein Classification" ] 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"site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614984.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510929" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G580", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tbc1d17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580", "locus": {} } ], "crossref": [ { "id": "A0A9J7G580", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G580", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768569", "url": "https://www.ncbi.nlm.nih.gov/gene/100768569", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768569", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768569", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CFAILME", "url": "https://omabrowser.org/oma/group/CFAILME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G580", "url": "https://www.orthodb.org/?gene=A0A9J7G580", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957:SF360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957:SF360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510929", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G580", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G580-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEASSYRVVFEKGGVYLHTSARKHQDPDSLIAGVIRVVEKDSDVLLHWAPVEEAGDPTQILFSKKDSSGVEPSTTEEEPTFDPGYEPDWAVISTVRPRPHLAEPRRGAEPSCPQSSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDPRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASPPDLPLRPDDEPEPGFEVISCVELGQRPTVERGPPVTEEEWTRHVGPDGRLHNIPELKNRIFSGGLSPGLRREAWKFLLGYLSWEGSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPSLHLLVACAILDMERDALMLSGFGANEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEVLGLAQPKEPSSPSPPISPLPLSTRAPLPPRPPREDVVAQPDSSLEILPEDDDGADS", "length": 648, "header": "tr|A0A9J7G580-1|A0A9J7G580_CRIGR Isoform 1 of TBC1 domain family member 17 OS=Cricetulus griseus OX=10029 GN=Tbc1d17 PE=4 SV=1 CANONICAL=A0A9J7G580-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G580-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580/entry#A0A9J7G580-1", "sequence": { "sequence": "MEASSYRVVFEKGGVYLHTSARKHQDPDSLIAGVIRVVEKDSDVLLHWAPVEEAGDPTQILFSKKDSSGVEPSTTEEEPTFDPGYEPDWAVISTVRPRPHLAEPRRGAEPSCPQSSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDPRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASPPDLPLRPDDEPEPGFEVISCVELGQRPTVERGPPVTEEEWTRHVGPDGRLHNIPELKNRIFSGGLSPGLRREAWKFLLGYLSWEGSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPSLHLLVACAILDMERDALMLSGFGANEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEVLGLAQPKEPSSPSPPISPLPLSTRAPLPPRPPREDVVAQPDSSLEILPEDDDGADS", "length": 648, "header": "tr|A0A9J7G580-1|A0A9J7G580_CRIGR Isoform 1 of TBC1 domain family member 17 OS=Cricetulus griseus OX=10029 GN=Tbc1d17 PE=4 SV=1 CANONICAL=A0A9J7G580-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G580", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G580", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768569", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768569", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N196-1", "protein_name": "TBC1 domain family member 17", "gene_name": "TBC1D17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEGAGYRVVFEKGGVYLHTSAKKHQDPDSLIAGVIRVVEKDNDVLLHWAPIEEAGDSSQIFFSKKDTSGGDSCTSEEEPTFDPGYEPDWAVISTVRPRPRHSEPKRGAEPSSPRGSWAFSVSLGELRSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSSSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHLEGTSPDLPPAPDDEPEPGFEVISCVELGPRPAVERAPPVTEEEWASHVGPEGRLQRVPELKARIFSGGLSPSLRREAWKFLLGYLSWEGSMEEHKAHVRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVTQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDPPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACGELPHNVQEVLGLASPAEPQSPSPSASPLPLSPTRAPPAPLPPADTATATQPDSSLEILPEEEDDEEGVES", "length": 652 }, "evidence": [ { "id": "A0A9J7G580", "url": "https://omabrowser.org/oma/group/A0A9J7G580/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RHU3-1", "protein_name": "TBC1 domain family member 17", "gene_name": "TBC1D17", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGAGYRVVFEKGGVYLHTSAKKHQDPDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQIFFSKKDPSGGDSCPSEEEPTFDPGYEPDWAVISTVRPRPRHSEPTRGAEPSSPRGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASPDLPPAPDDEPEPGFEVISCVELGPRPAVERAPPVTEEEWARHVGPEGRLQQVPELKARIFSGGLSPSLRREAWKFLLGYLSWEGSAEEHKAHVRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVTQNEVDAFWCFCGFMELVHRNFEESQETMKRQLGQLLLLLRVLDPPLCDFLDAQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACRELPHNVQEVLGLAPPAEPQSPSPPASPLPLSPARAPPAPPPPADTVQQPDSSLEILPEEEEEESADS", "length": 649 }, "evidence": [ { "id": "A0A9J7G580", "url": "https://omabrowser.org/oma/group/A0A9J7G580/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4KG91-1", "protein_name": "TBC1 domain family member 15", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMEATELQDLSDDADYAASQQQGSASMMRSDSGKRSLQSEHEDAVLIYLKDNVAIHPTQFASERISGRLKLTKQDSVLFLSWIPYKGQTSNAKLSEKDRSLYTITAVPFTEVRSIRRHTPALGWQYVIVVLSSGLAFPPLYFYNGGVREFLAMVKQHVFLARSSEDQNVFIVNDFQSPLQRTLSSLELPSSLPVASGQSVYPLDGGSSSENQRRTSSDVGNRVSSVSQSGFRKQKSHDPTRDLSIHLLEKFSLVTKFARDTTTQLFSENNGFGSIDKRWNNQPVHSYPEKLSNIAEEKHHEIRHSYSENDLLKDDEISYIDVPADPLEFDKLSLMWGKPRQPPMGHKERRNDISPSIKCRISTEYFTALLDSEGRVVESKALRERVFYGGIEHQLRREVWPFLLGYYAYDSTYAEREYLRSVKRMEYATLKQQWQSISPEQAKRFTKYRERKGLIDKDVVRTDRAFEYYEGDDNLHVNSMRDILLTYSFYNFDLGYCQGMSDYLSPILFVMEDESESFWCFVALMERLGPNFNRDQNGMHTQLFALSKLVELLDSPLHNYFKENDCLNYFFCFRWILIQFKREFEYEKTMQLWEVMWTHYLSEHFHLYVCVAVLKRCRSKIMGEQMDFDTLLKFINELSGHIDLDSTVRDAEALCIEAGENGAASIPPGTPPSLPLDDGTLYPQEDDVL", "length": 690 }, "evidence": [ { "id": "A0A9J7G580", "url": "https://omabrowser.org/oma/group/A0A9J7G580/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8BYH7-1", "protein_name": "TBC1 domain family member 17", "gene_name": "Tbc1d17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGSSYRVVFEKGGVYLHTSARKHQDPDSLIAGVIRVVEKDSDVFLHWAPVEEAGDPTQILFKKDPSRGEPSTSEEEPTFDPGYEPDWAVISTVRPQPHLAEPRKGAEPSSSRSSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASSPNLPPLPDDEPEPGFEVISCVELGQRPTVERAPPVTEEEWNRYVGPEGRLQNVPELKNRIFSGGLSPGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLSLLHDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEILGLAQPEEPSSPSPPVSPMPLSPTRAPLPPPLPEEVIPQPDSSLEILPEDEDGA", "length": 645 }, "evidence": [ { "id": "A0A9J7G580", "url": "https://omabrowser.org/oma/group/A0A9J7G580/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HA65-1", "protein_name": "TBC1 domain family member 17", "gene_name": "TBC1D17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGAGYRVVFEKGGVYLHTSAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPGYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDSSLEILPEEEDEGADS", "length": 648 }, "evidence": [ { "id": "A0A9J7G580", "url": "https://omabrowser.org/oma/group/A0A9J7G580/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G580", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G580", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G580", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G580", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G580", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G580", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G580" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 311, "end_pos": 521, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"MSEANRSVVSEFVFLGLSNSWTIQVFLFLFSCVFYVASLLGNFLIVLTVTSDPHLQSPMYFLLANLSFLDLIFCSSTAPKMIYDLFRRHKTISLGGCITQIFFIHAVGGTEMVLLIAMAFDRYVAICKPLHYLTIMSPQKCILFLVASWIIGLIHSLTQLVFVVDLPFCGPNELDSFFCDLPRFIKLACVDTYTLGFMVTANSGFISVASFLILIISYIFILMTVQKKSLGSLSKALSTLSAHVMVVVLFFGPLIFFYMWPFPTSHLDKFLALFDAVITPFLNPVIYTLRNKEMKVAMKRLCSQQRCHVQ", "length": 310, "header": "tr|A0A9J7G583-1|A0A9J7G595_CRIGR Computationally mapped isoform of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100774881 PE=3 SV=1 CANONICAL=A0A9J7G595-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G595-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G595/entry#A0A9J7G595-1", "sequence": { "sequence": "MSEANRSVVSEFVFLGLSNSWTIQVFLFLFSCVFYVASLLGNFLIVLTVTSDPHLQSPMYFLLANLSFLDLIFCSSTAPKMIYDLFRRHKTISLGGCITQIFFIHAVGGTEMVLLIAMAFDRYVAICKPLHYLTIMSPQKCILFLVASWIIGLIHSLTQLVFVVDLPFCGPNELDSFFCDLPRFIKLACVDTYTLGFMVTANSGFISVASFLILIISYIFILMTVQKKSLGSLSKALSTLSAHVMVVVLFFGPLIFFYMWPFPTSHLDKFLALFDAVITPFLNPVIYTLRNKEMKVAMKRLCSQFINYYKVS", "length": 312, "header": "tr|A0A9J7G595-1|A0A9J7G595_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100774881 PE=3 SV=1 CANONICAL=A0A9J7G595-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G583", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G583" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G583", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G583" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774881", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774881", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G595", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G595" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G595", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G595" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G595", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G595" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G595", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G595" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 287, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G615-1", "uniprot_ac": "A0A9J7G615", "uniprot_id": "A0A9J7G615_CRIGR", "mass": { "chemical_mass": 74824.0, "monoisotopic_mass": 74824.0 }, "refseq": { "ac": "XP_027277271", "name": "transmembrane 9 superfamily member 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277271" }, "gene_names": [ { "name": "Tm9sf4", "type": "recommended", "evidence": [ { "id": "A0A9J7G615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615" } ] }, { "name": "Tm9sf4", "type": "synonym", "evidence": [ { "id": "XP_027277271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277271" } ] } ], "protein_names": [ { "name": "Transmembrane 9 superfamily member", "type": "recommended", "evidence": [ { "id": "A0A9J7G615", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615/entry#names_and_taxonomy" } ] }, { "name": "transmembrane 9 superfamily member 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027277271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277271" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277271" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G615", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tm9sf4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615", "locus": {} } ], "crossref": [ { "id": "A0A9J7G615", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G615", "database": "AlphaFoldDB", "categories": [] }, { "id": "100754311", "url": "https://www.ncbi.nlm.nih.gov/gene/100754311", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004240", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004240", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754311", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754311", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G615", "url": "https://www.orthodb.org/?gene=A0A9J7G615", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10766:SF55", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10766:SF55", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02990", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02990", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G584", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G584", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G584-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G584-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G615", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G615-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9N5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JV79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JV79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV79-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAMQVWWPRFLLLLCLTCKTSTFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPSKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCSQSSKPVTLTVEQSRLVAERITEDYYVHLIADNLPVATRLELYSNNRDNDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKTDEKNSCILPEGTNSSPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTLEESGWKLVHGDVFRPPQHPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 644, "header": "tr|A0A9J7G615-1|A0A9J7G615_CRIGR Isoform 1 of Transmembrane 9 superfamily member OS=Cricetulus griseus OX=10029 GN=Tm9sf4 PE=3 SV=1 CANONICAL=A0A9J7G615-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G584-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615/entry#A0A9J7G584-1", "sequence": { "sequence": "MKQVWWPRFLLLLCLTCKTSTFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPSKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCSQSSKPVTLTVEQSRLVAERITEDYYVHLIADNLPVATRLELYSNNRDNDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKTDEKNSCILPEGTNSSPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTLEESGWKLVHGDVFRPPQHPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 641, "header": "tr|A0A9J7G584-1|A0A9J7G615_CRIGR Computationally mapped isoform of Transmembrane 9 superfamily member OS=Cricetulus griseus OX=10029 GN=Tm9sf4 PE=3 SV=1 CANONICAL=A0A9J7G615-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G5W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615/entry#A0A9J7G5W5-1", "sequence": { "sequence": "MAAAMVWWPRFLLLLCLTCKTSTFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPSKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCSQSSKPVTLTVEQSRLVAERITEDYYVHLIADNLPVATRLELYSNNRDNDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKTDEKNSCILPEGTNSSPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTLEESGWKLVHGDVFRPPQHPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 643, "header": "tr|A0A9J7G5W5-1|A0A9J7G5W5_CRIGR Computationally mapped isoform of Transmembrane 9 superfamily member OS=Cricetulus griseus OX=10029 GN=Tm9sf4 PE=3 SV=1 CANONICAL=A0A9J7G615-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G615-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615/entry#A0A9J7G615-1", "sequence": { "sequence": "MAAAMQVWWPRFLLLLCLTCKTSTFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPSKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCSQSSKPVTLTVEQSRLVAERITEDYYVHLIADNLPVATRLELYSNNRDNDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKTDEKNSCILPEGTNSSPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTLEESGWKLVHGDVFRPPQHPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 644, "header": "tr|A0A9J7G615-1|A0A9J7G615_CRIGR Isoform 1 of Transmembrane 9 superfamily member OS=Cricetulus griseus OX=10029 GN=Tm9sf4 PE=3 SV=1 CANONICAL=A0A9J7G615-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615/entry#A0A9J7G9N5-1", "sequence": { "sequence": "MKVWWPRFLLLLCLTCKTSTFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPSKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCSQSSKPVTLTVEQSRLVAERITEDYYVHLIADNLPVATRLELYSNNRDNDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKTDEKNSCILPEGTNSSPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTLEESGWKLVHGDVFRPPQHPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTALMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID", "length": 640, "header": "tr|A0A9J7G9N5-1|A0A9J7G9N5_CRIGR Computationally mapped isoform of Transmembrane 9 superfamily member OS=Cricetulus griseus OX=10029 GN=Tm9sf4 PE=3 SV=1 CANONICAL=A0A9J7G615-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JV79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615/entry#A0A9J7JV79-1", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A9J7G615" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to membrane", "id": "GO:0072657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072657", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G615", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G615" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G585-1", "uniprot_ac": "A0A9J7G585", "uniprot_id": "A0A9J7G585_CRIGR", "mass": { "chemical_mass": 11510.0, "monoisotopic_mass": 11510.0 }, "refseq": { "ac": "XP_027276777", "name": "ATP synthase subunit g, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276777" }, "gene_names": [ { "name": "LOC100769978", "type": "recommended", "evidence": [ { "id": "A0A9J7G585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585" } ] }, { "name": "LOC100769978", "type": "synonym", "evidence": [ { "id": "XP_027276777", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276777" } ] } ], "protein_names": [ { "name": "ATP synthase F(0) complex subunit g, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A9J7G585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585/entry#names_and_taxonomy" } ] }, { "name": "ATP synthase subunit g, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_027276777", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276777" } ] }, { "name": "ATPase subunit g", "type": "synonym", "evidence": [ { "id": "A0A9J7G585", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276777" } ] }, { "annotation": "Subunit g, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G585", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585#function" }, { "database": "UniProtKB", "id": "PIRNR017835", "url": "https://www.uniprot.org/uniprotkb/PIRNR017835#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G585", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100769978", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585", "locus": {} } ], "crossref": [ { "id": "A0A9J7G585", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G585", "database": "AlphaFoldDB", "categories": [] }, { "id": "100769978", "url": "https://www.ncbi.nlm.nih.gov/gene/100769978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016702", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016702", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769978", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G585", "url": "https://www.orthodb.org/?gene=A0A9J7G585", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12386", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12386", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276777", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G585", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G585-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARFIRNFAEKAPALVSAAVTYTKPRLATFWYYAKVELVPPTPAEIPAAIQSVKKIIQSAKTGSFKQLTVKEAVLNSLVTTELRMWFYIGEIISKRGIVGYDV", "length": 103, "header": "tr|A0A9J7G585-1|A0A9J7G585_CRIGR Isoform 1 of ATP synthase F(0) complex subunit g, mitochondrial OS=Cricetulus griseus OX=10029 GN=LOC100769978 PE=3 SV=1 CANONICAL=A0A9J7G585-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G585-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585/entry#A0A9J7G585-1", "sequence": { "sequence": "MARFIRNFAEKAPALVSAAVTYTKPRLATFWYYAKVELVPPTPAEIPAAIQSVKKIIQSAKTGSFKQLTVKEAVLNSLVTTELRMWFYIGEIISKRGIVGYDV", "length": 103, "header": "tr|A0A9J7G585-1|A0A9J7G585_CRIGR Isoform 1 of ATP synthase F(0) complex subunit g, mitochondrial OS=Cricetulus griseus OX=10029 GN=LOC100769978 PE=3 SV=1 CANONICAL=A0A9J7G585-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 42, "start_aa": "Thr", "end_pos": 42, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr42", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G585", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G585", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769978", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial membrane", "id": "GO:0031966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031966", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G585", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585" } ], "pmid": "" }, { "name": "proton-transporting ATP synthase complex", "id": "GO:0045259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045259", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G585", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton transmembrane transporter activity", "id": "GO:0015078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015078", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G585", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proton motive force-driven ATP synthesis", "id": "GO:0015986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015986", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G585", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G585" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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CANONICAL=A0A9J7G594-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 505, "start_aa": "Thr", "end_pos": 505, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr505", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027276585.1. 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G5B5-1", "uniprot_ac": "A0A9J7G5B5", "uniprot_id": "A0A9J7G5B5_CRIGR", "mass": { "chemical_mass": 79485.0, "monoisotopic_mass": 79485.0 }, "refseq": { "ac": "XP_016836346", "name": "BMP/retinoic acid-inducible neural-specific protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836346" }, "gene_names": [ { "name": "Brinp3", 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 121 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613634.1) and transcript sequence (IACG01057144.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016836346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836346" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5B5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5B5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Brinp3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5B5", "locus": {} } ], "crossref": [ { "id": "A0A9J7G5B5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G5B5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100774253", "url": "https://www.ncbi.nlm.nih.gov/gene/100774253", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774253", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774253", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G5B5", "url": "https://www.orthodb.org/?gene=A0A9J7G5B5", "database": "OrthoDB", "categories": [ "Protein 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"publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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CANONICAL=A0A9J7G5D1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5D1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751827", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751827", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5D1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276864" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100756650", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D8", "locus": {} } ], "crossref": [ { "id": "cd15939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756650", "url": "https://www.ncbi.nlm.nih.gov/gene/100756650", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756650", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756650", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G5D8", "url": "https://www.orthodb.org/?gene=A0A9J7G5D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276864", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G5D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQNNSVSEFTLLGLTQDPAEQKALFVMFLLFYIGIMVGNLLIVGTVIGSPSLDSPMYFFLAYLSLIDAMYSTTILPKLLIDLLCDKKTISFTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQWVCIHLVVLSWXGAFAHALLQVLSVYKLPFCGPNVIDHFTCDMYPLLGLACTDTSFLGLSVVANNGAMSVVVFILLLVSYGIILNSVKTHSQEGRRKALSTCSSHIMVVVLFFVPCIFMYVRPVSNFPIDKFITVFYTVFTPILNPLIYTLRNLEIQKSMEKLWGKMFTGDRIRISSFYS", "length": 316, "header": "tr|A0A9J7G5D8-1|A0A9J7G5D8_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100756650 PE=3 SV=1 CANONICAL=A0A9J7G5D8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G5D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D8/entry#A0A9J7G5D8-1", "sequence": { "sequence": "MGQNNSVSEFTLLGLTQDPAEQKALFVMFLLFYIGIMVGNLLIVGTVIGSPSLDSPMYFFLAYLSLIDAMYSTTILPKLLIDLLCDKKTISFTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQWVCIHLVVLSWXGAFAHALLQVLSVYKLPFCGPNVIDHFTCDMYPLLGLACTDTSFLGLSVVANNGAMSVVVFILLLVSYGIILNSVKTHSQEGRRKALSTCSSHIMVVVLFFVPCIFMYVRPVSNFPIDKFITVFYTVFTPILNPLIYTLRNLEIQKSMEKLWGKMFTGDRIRISSFYS", "length": 316, "header": "tr|A0A9J7G5D8-1|A0A9J7G5D8_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100756650 PE=3 SV=1 CANONICAL=A0A9J7G5D8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"UniProtKB", "id": "A0A9J7G5D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G5D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G5D9-1", "uniprot_ac": "A0A9J7G5D9", "uniprot_id": "A0A9J7G5D9_CRIGR", "mass": { "chemical_mass": 26480.0, "monoisotopic_mass": 26480.0 }, "refseq": { "ac": "XP_003502661", "name": "guanidinoacetate N-methyltransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502661" }, "gene_names": [ { "name": "Gamt", "type": "recommended", 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NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 260 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613904.1) and transcript sequence (IACG01095928.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003502661.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502661" } ] }, { "annotation": "Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor. Important in nervous system development.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D9#function" }, { "database": "UniProtKB", "id": "ARBA00060232", "url": "https://www.uniprot.org/uniprotkb/ARBA00060232#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gamt", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D9", "locus": {} } ], "crossref": [ { "id": "A0A9J7G5D9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G5D9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755964", "url": "https://www.ncbi.nlm.nih.gov/gene/100755964", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026480", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026480", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755964", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755964", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G5D9", "url": "https://www.orthodb.org/?gene=A0A9J7G5D9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32379:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32379:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502661", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10656", "url": "https://www.rhea-db.org/rhea/10656", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G5D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSAASPLFAPGEDCGPAWRAAPAAYDASDTHLQILGKPVMERWETPYMHALAAAAASRGGRVLEVGFGMAIAASRVQEAPIEEHWIIECNDGVFQRLQDWALRQPHKVVPLKGLWEEVAPTLPDGHFNGILYDTYPLSEETWHTHQFNFIKKHAFRLLKPGGILTYCNLTSWGELLKSKFTDITTMFEETQVPALQEAGFRRENIRTEVMALVPPADCRYYAFPQMITPLVTKH", "length": 236, "header": "tr|A0A9J7G5D9-1|A0A9J7G5D9_CRIGR Isoform 1 of Guanidinoacetate N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Gamt PE=3 SV=1 CANONICAL=A0A9J7G5D9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G5D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D9/entry#A0A9J7G5D9-1", "sequence": { "sequence": "MSSSAASPLFAPGEDCGPAWRAAPAAYDASDTHLQILGKPVMERWETPYMHALAAAAASRGGRVLEVGFGMAIAASRVQEAPIEEHWIIECNDGVFQRLQDWALRQPHKVVPLKGLWEEVAPTLPDGHFNGILYDTYPLSEETWHTHQFNFIKKHAFRLLKPGGILTYCNLTSWGELLKSKFTDITTMFEETQVPALQEAGFRRENIRTEVMALVPPADCRYYAFPQMITPLVTKH", "length": 236, "header": "tr|A0A9J7G5D9-1|A0A9J7G5D9_CRIGR Isoform 1 of Guanidinoacetate N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Gamt PE=3 SV=1 CANONICAL=A0A9J7G5D9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5D9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G634-1", "uniprot_ac": "A0A9J7G634", "uniprot_id": "A0A9J7G634_CRIGR", "mass": { "chemical_mass": 164854.0, "monoisotopic_mass": 164854.0 }, "refseq": { "ac": "XP_027277433", "name": "ribosome-binding protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277433" }, "gene_names": [ { "name": "Rrbp1", "type": "recommended", "evidence": [ { "id": "A0A9J7G634", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634" } ] }, { "name": "Rrbp1", "type": "synonym", "evidence": [ { "id": "XP_027277433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277433" } ] } ], "protein_names": [ { "name": "Ribosome-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7G634", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634/entry#names_and_taxonomy" } ] }, { "name": "Ribosome receptor protein", "type": "synonym", "evidence": [ { "id": "A0A9J7G634", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634/entry#names_and_taxonomy" } ] }, { "name": "ribosome-binding protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027277433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277433" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277433", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277433" } ] }, { "annotation": "Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5G5#function" }, { "database": "UniProtKB", "id": "ARBA00053537", "url": "https://www.uniprot.org/uniprotkb/ARBA00053537#function" }, { "database": "UniProtKB", "id": "A0A9J7G634", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G634", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rrbp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634", "locus": {} } ], "crossref": [ { "id": "100768883", "url": "https://www.ncbi.nlm.nih.gov/gene/100768883", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768883", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768883", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G634", "url": "https://www.orthodb.org/?gene=A0A9J7G634", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18939:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18939:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277433", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277433", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G5G5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G634", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G634-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9W5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9W5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPDHDLDSNVTIILKEPVRVPAMAVAPTSVHSSMVHTPVATVPAMPQEKLASSPKDKKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASAPATSSQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGAQNQTKKGEGAQNQGKKGEGAQNQTKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGGEGAQNQGKKGETNQNQAKKGDGVQNQAKKGEGPQNQGKKGEATQNQGKKMEGAQNQGKKTEGTPNQGKKGEGTQNQAKKLEDSPNQGKKAEGAQNQGKKGEGAQNQTKKGEGPQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQGKKGEGAQNQGKKGEGAQNQGKKLEDSPNQGKKAEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGDGAQNQGKKGEGVQNQGKKLEDSPNQGKKAEGTQNQGKKGEGTQNQGKKGDGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGDGNPNQGKKGEGAPNQSRKTDAVANQGTKTEGVSNQGKKAEGSPNQGKKAEGSPNQGKKAEGSPNQGKKAEGAPNQGKKVEGSPNQGKKVDTASNQGNKLESAPAQGKNSGMVQSQEAPKQEAPAKKKSGSKRKAEPGSPDCDSPLFLPYKTLVSTVGSMMFNEGEAQRLIEILSEKIGVTQDTWHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYQDHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQSSHASLRADAEKAQEQQQRMAELHSKLQSSEVEVKSKCEELSNLHGQLKEARAENEQLTERIHSIETLLEAGQAQNTQASQAEADQQQIRLKELESQVLSLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERTCEEKLHSLTQAKEESEKQLHLAEAQTKEVLLALLPDLSISAHQNYAEWLREVKEKGSELLKKPPASLEPSLDVVSKLREAEETQNSLQAECDQYRSILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELQKSRVTVKHLEDIVEKLKGELESSDQVREHTSFLEAELEKHMAAASAECQNYAKEVAGLRQLLLDSQSQLDEAKSEAQKQSTELALVRQQLSDMKSHVEDGDVAGSPAVPPAEQDPIKLKTQLERTEAILEDEQTRRQKLTAEFEEAQSTACRLQEELEKLRAAGGPLESSGIEEVTQLKERLEKEKRLTSDLGRAATKLQELLKTTQEQLTKEKDTVKKLQEQLEKAEDGSSSKEGTSV", "length": 1526, "header": "tr|A0A9J7G634-1|A0A9J7G634_CRIGR Isoform 1 of Ribosome-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Rrbp1 PE=4 SV=1 CANONICAL=A0A9J7G634-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G5G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634/entry#A0A9J7G5G5-1", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPDHDLDSNVTIILKEPVRVPAMAVAPTSVHSSMVHTPVATVPAMPQEKLASSPKDKKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASAPATSSQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGAQNQTKKGEGAQNQGKKGEGAQNQTKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGGEGAQNQGKKGETNQNQAKKGDGVQNQAKKGEGPQNQGKKGEATQNQGKKMEGAQNQGKKTEGTPNQGKKGEGTQNQAKKLEDSPNQGKKAEGAQNQGKKGEGAQNQTKKGEGPQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQGKKGEGAQNQGKKGEGAQNQGKKLEDSPNQGKKAEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGDGAQNQGKKGEGVQNQGKKLEDSPNQGKKAEGTQNQGKKGEGTQNQGKKGDGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGDGNPNQGKKGEGAPNQSRKTDAVANQGTKTEGVSNQGKKAEGSPNQGKKAEGSPNQGKKAEGSPNQGKKAEGAPNQGKKVEGSPNQGKKVDTASNQGNKLESAPAQGKNSGMVQSQEAPKQEAPAKKKSGSKRKAEPGSPDCDSPLFLPYKTLVSTVGSMMFNEGEAQRLIEILSEKIGVTQDTWHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYQDHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQSSHASLRADAEKAQEQQQRMAELHSKLQSSEVEVKSKCEELSNLHGQLKEARAENEQLTERIHSIETLLEAGQAQNTQASQAEADQQQIRLKELESQVLSLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERTCEEKLHSLTQAKEESEKQLHLAEAQTKEVLLALLPDLSISAHQNYAEWLREVKEKGSELLKKPPASLEPSLDVVSKLREAEETQNSLQAECDQYRSILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELQKSRVTVKHLEDIVEKLKGELESSDQVREHTSFLEAELEKHMAAASAECQNYAKEVAGLRQLLLDSQSQLDEAKSEAQKQSTELALLKTQLERTEAILEDEQTRRQKLTAEFEEAQSTACRLQEELEKLRAAGGPLESSGIEEVTQLKERLEKEKRLTSDLGRAATKLQELLKTTQEQLTKEKDTVKKLQEQLEKAEDGSSSKEGTSV", "length": 1494, "header": "tr|A0A9J7G5G5-1|A0A9J7G634_CRIGR Computationally mapped isoform of Ribosome-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Rrbp1 PE=4 SV=1 CANONICAL=A0A9J7G634-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G634-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634/entry#A0A9J7G634-1", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPDHDLDSNVTIILKEPVRVPAMAVAPTSVHSSMVHTPVATVPAMPQEKLASSPKDKKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASAPATSSQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGAQNQTKKGEGAQNQGKKGEGAQNQTKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGGEGAQNQGKKGETNQNQAKKGDGVQNQAKKGEGPQNQGKKGEATQNQGKKMEGAQNQGKKTEGTPNQGKKGEGTQNQAKKLEDSPNQGKKAEGAQNQGKKGEGAQNQTKKGEGPQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQGKKGEGAQNQGKKGEGAQNQGKKLEDSPNQGKKAEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGDGAQNQGKKGEGVQNQGKKLEDSPNQGKKAEGTQNQGKKGEGTQNQGKKGDGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGDGNPNQGKKGEGAPNQSRKTDAVANQGTKTEGVSNQGKKAEGSPNQGKKAEGSPNQGKKAEGSPNQGKKAEGAPNQGKKVEGSPNQGKKVDTASNQGNKLESAPAQGKNSGMVQSQEAPKQEAPAKKKSGSKRKAEPGSPDCDSPLFLPYKTLVSTVGSMMFNEGEAQRLIEILSEKIGVTQDTWHKATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMASEKAKAAAGEAKVKKQLVAREQEIAAVQARMQASYQDHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRDALNQATSQVESKQNTELAKLRQELSKVNKELVEKSEASRQEEQQRKALEAKAATFEKQVLQLQASHKESEEALQKRLEEVTRELCRAQSSHASLRADAEKAQEQQQRMAELHSKLQSSEVEVKSKCEELSNLHGQLKEARAENEQLTERIHSIETLLEAGQAQNTQASQAEADQQQIRLKELESQVLSLEKETSELKEAMEQQKGKNNDLREKNWKAMEALALAERTCEEKLHSLTQAKEESEKQLHLAEAQTKEVLLALLPDLSISAHQNYAEWLREVKEKGSELLKKPPASLEPSLDVVSKLREAEETQNSLQAECDQYRSILAETEGMLKDLQKSVEEEERVWKAKVGAAEEELQKSRVTVKHLEDIVEKLKGELESSDQVREHTSFLEAELEKHMAAASAECQNYAKEVAGLRQLLLDSQSQLDEAKSEAQKQSTELALVRQQLSDMKSHVEDGDVAGSPAVPPAEQDPIKLKTQLERTEAILEDEQTRRQKLTAEFEEAQSTACRLQEELEKLRAAGGPLESSGIEEVTQLKERLEKEKRLTSDLGRAATKLQELLKTTQEQLTKEKDTVKKLQEQLEKAEDGSSSKEGTSV", "length": 1526, "header": "tr|A0A9J7G634-1|A0A9J7G634_CRIGR Isoform 1 of Ribosome-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Rrbp1 PE=4 SV=1 CANONICAL=A0A9J7G634-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G634/entry#A0A9J7G9W5-1", "sequence": { "sequence": "MDIYDTQTLGVVVFGGFMVVSAIGIFLVSTFSMKETSYEEALANQRKEMAKTHHQKGEKKKKEKTVEKKGKTKKKEEKPNGKIPDHDLDSNVTIILKEPVRVPAMAVAPTSVHSSMVHTPVATVPAMPQEKLASSPKDKKKKEKKVAKVEPAVSSIVNSIQVLASKSAILEATPKEVPMVAVPPVGSKASAPATSSQGKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGAQNQTKKGEGAQNQGKKGEGAQNQTKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGEGAQNQAKKGGEGAQNQGKKGETNQNQAKKGDGVQNQAKKGEGPQNQGKKGEATQNQGKKMEGAQNQGKKTEGTPNQGKKGEGTQNQAKKLEDSPNQGKKAEGAQNQGKKGEGAQNQTKKGEGPQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGPQNQGKKGEGAQNQGKKGEGAQNQGKKLEDSPNQGKKAEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGDGAQNQGKKGEGVQNQGKKLEDSPNQGKKAEGTQNQGKKGEGTQNQGKKGDGAQNQGKKGEGAQNQGKKGEGAQNQGKKGEGAQNQGKKGDGNPNQGKKGEGAPNQSRKTDAVANQGTKTEGVSNQGKKAEGSPNQGKKAEGSPNQGKKAEGSPNQGKKAEGAPNQGKKVEGSPNQGKKVDTASNQGNKLESAPAQGKNSGMVQSQEAPKQEAPAKKKSGSKRKAEPVC", "length": 761, "header": "tr|A0A9J7G9W5-1|A0A9J7G9W5_CRIGR Computationally mapped isoform of Ribosome-binding protein 1 isoform X5 OS=Cricetulus griseus OX=10029 GN=Rrbp1 PE=4 SV=1 CANONICAL=A0A9J7G634-1" }, "locus": {} } ], 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5H3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5H3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5H3" }, { "id": "SM00329", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00329" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipid-binding serum glycoprotein C-terminal", "eco_id": "ECO_0000259", "start_pos": 271, "end_pos": 471, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G5H3", "database": "UniProtKB", "url": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"monoisotopic_mass": 42422.0 }, "refseq": { "ac": "XP_027273369", "name": "chitinase-3-like protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273369" }, "gene_names": [ { "name": "Chi3l1", "type": "recommended", "evidence": [ { "id": "A0A9J7G5H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5H7" } ] }, { "name": "Chi3l1", "type": "synonym", "evidence": [ { "id": "XP_027273369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273369" } ] } ], "protein_names": [ { "name": "Chitinase-3-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7G5H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5H7/entry#names_and_taxonomy" } ] }, { "name": "Cartilage glycoprotein 39", "type": "synonym", "evidence": [ { "id": "A0A9J7G5H7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5H7/entry#names_and_taxonomy" } ] }, { "name": "chitinase-3-like protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027273369", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273369" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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"tr|A0A9J7JRK2-1|A0A9J7JRK2_CRIGR Computationally mapped isoform of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100758908 PE=3 SV=1 CANONICAL=A0A9J7G5T6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"https://www.ncbi.nlm.nih.gov/protein/XP_027276999" }, "gene_names": [ { "name": "LOC113836362", "type": "recommended", "evidence": [ { "id": "A0A9J7G5T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5T7" } ] }, { "name": "LOC113836362", "type": "synonym", "evidence": [ { "id": "XP_027276999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276999" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7G5T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5T7/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: olfactory receptor 8K5-like", "type": "synonym", "evidence": [ { "id": "XP_027276999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276999" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276999" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5T7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113836362", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5T7", "locus": {} } ], "crossref": [ { "id": "A0A9J7G5T7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G5T7", "database": "AlphaFoldDB", "categories": [] }, { "id": "113836362", "url": "https://www.ncbi.nlm.nih.gov/gene/113836362", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113836362", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836362", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G5T7", "url": "https://www.orthodb.org/?gene=A0A9J7G5T7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276999", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G5T7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5T7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAHHNVCLNTEFILTRITRRAELQLPLLGVFLVTYGVAMIGNLSMIILTKLDSRLHTPMYYFIRHLAFIDLGNCTVIYPKMMVNFVVDQNVISYYACATQMAFYITFIISELFILSSMAYDRYVAICNPLCYSVIMTQRRCHVLVGIPYLYSIFQAVMITSKIFTLAFCGSNVISHFYCDNVPMLLLLCSNARDIELLIILFSALNLISSLFVVLVSYLLILLAIYGMHSAEGRKKAFSTCGSHLTVVVVFYGTLLFMYLQPKSTHSFETDKIASVFYTLVIPMLNPLIYSFRNKEVKRAFLKVFKDRCKLCT", "length": 313, "header": "tr|A0A9J7G5T7-1|A0A9J7G5T7_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC113836362 PE=3 SV=1 CANONICAL=A0A9J7G5T7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G5T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5T7/entry#A0A9J7G5T7-1", "sequence": { "sequence": "MAHHNVCLNTEFILTRITRRAELQLPLLGVFLVTYGVAMIGNLSMIILTKLDSRLHTPMYYFIRHLAFIDLGNCTVIYPKMMVNFVVDQNVISYYACATQMAFYITFIISELFILSSMAYDRYVAICNPLCYSVIMTQRRCHVLVGIPYLYSIFQAVMITSKIFTLAFCGSNVISHFYCDNVPMLLLLCSNARDIELLIILFSALNLISSLFVVLVSYLLILLAIYGMHSAEGRKKAFSTCGSHLTVVVVFYGTLLFMYLQPKSTHSFETDKIASVFYTLVIPMLNPLIYSFRNKEVKRAFLKVFKDRCKLCT", "length": 313, "header": "tr|A0A9J7G5T7-1|A0A9J7G5T7_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC113836362 PE=3 SV=1 CANONICAL=A0A9J7G5T7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003613665.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497865" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5U1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hdc", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5U1", "locus": {} } ], "crossref": [ { "id": "A0A9J7G5U1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G5U1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06450", "database": "CDD", "categories": [ "Protein Classification" ] }, { 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based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5U1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5U1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753889", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753889", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5U1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "pyridoxal phosphate binding", "id": "GO:0030170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030170", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5U1" } ], "pmid": "" }, { "name": "histidine decarboxylase activity", "id": "GO:0004398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004398", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5U1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "L-histidine catabolic process", "id": "GO:0006548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006548", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5U1" } ], "pmid": "" }, { "name": "histamine biosynthetic process", "id": "GO:0001694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001694", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5U1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5U1" } ], "pmid": "" }, { "name": "catecholamine biosynthetic 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"database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G5W1", "url": "https://www.orthodb.org/?gene=A0A9J7G5W1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G7V8", "url": "https://www.orthodb.org/?gene=A0A9J7G7V8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934:SF136", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934:SF136", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00271", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00271", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277032", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277032", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G5W1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G5Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7W4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPLGPVKFWKPGTEGPGVSIAEERQSVAENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTLVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTCVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEDAFDQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPKMSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDQ", "length": 703, "header": "tr|A0A9J7G7V8-1|A0A9J7G7V8_CRIGR Isoform 1 of Probable ATP-dependent RNA helicase DHX35 OS=Cricetulus griseus OX=10029 GN=Dhx35 PE=3 SV=1 CANONICAL=A0A9J7G7V8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G5W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8/entry#A0A9J7G5W1-1", "sequence": { "sequence": "MAAPLGPVKFWKPGTEGPGVSIAEERQSVAENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTLVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTCVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEDAFDQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPKMSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEKPPRCTCP", "length": 655, "header": "tr|A0A9J7G5W1-1|A0A9J7G7V8_CRIGR Computationally mapped isoform of Probable ATP-dependent RNA helicase DHX35 OS=Cricetulus griseus OX=10029 GN=Dhx35 PE=3 SV=1 CANONICAL=A0A9J7G7V8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G5Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8/entry#A0A9J7G5Z7-1", "sequence": { "sequence": "MLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTCVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEDAFDQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPKMSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDQ", "length": 548, "header": "tr|A0A9J7G5Z7-1|A0A9J7G5Z7_CRIGR Computationally mapped isoform of RNA helicase OS=Cricetulus griseus OX=10029 GN=Dhx35 PE=4 SV=1 CANONICAL=A0A9J7G7V8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8/entry#A0A9J7G7V8-1", "sequence": { "sequence": "MAAPLGPVKFWKPGTEGPGVSIAEERQSVAENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTLVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTCVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEDAFDQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPKMSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDQ", "length": 703, "header": "tr|A0A9J7G7V8-1|A0A9J7G7V8_CRIGR Isoform 1 of Probable ATP-dependent RNA helicase DHX35 OS=Cricetulus griseus OX=10029 GN=Dhx35 PE=3 SV=1 CANONICAL=A0A9J7G7V8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8/entry#A0A9J7G7W4-1", "sequence": { "sequence": "MAAPLGPVKFWKPGTEGPGVSIAEERQSVAENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTLVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTCVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTEDAFDQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPKMSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDQ", "length": 668, "header": "tr|A0A9J7G7W4-1|A0A9J7G7W4_CRIGR Computationally mapped isoform of RNA helicase OS=Cricetulus griseus OX=10029 GN=Dhx35 PE=4 SV=1 CANONICAL=A0A9J7G7V8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8/entry#A0A9J7GAD8-1", "sequence": { "sequence": "MAAPLGPVKFWKPGTEGPGVSIAEERQSVAENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVENYQTLVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTCVTLTVEGRTFPVDIFYLQSPVPDYIKATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQMKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRNRSGKCYRLYTGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQNVFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVREQLKKLLVKFQVPKMSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGTHLSLKAKRAKVQDQ", "length": 643, "header": "tr|A0A9J7GAD8-1|A0A9J7GAD8_CRIGR Computationally mapped isoform of Probable ATP-dependent RNA helicase DHX35 OS=Cricetulus griseus OX=10029 GN=Dhx35 PE=3 SV=1 CANONICAL=A0A9J7G7V8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 115, "start_aa": "Thr", "end_pos": 115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr115", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5W1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G5W1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761819", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761819", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H6T7-1", "G3H7V9-1", "G3HCT4-1", "G3HIC5-1", "G3HIL5-1", "A0A061IR73-1", "G3GXG9-1", "G3I8R9-1", "G3HH18-1", "A0A9J7FU33-1", "G3I2I1-1", "A0A9J7FTT2-1", "G3IEZ7-1", "G3HKQ8-1", "G3HMB1-1", "G3HCV0-1", "G3HX41-1", "G3I6K0-1", "G3HTL1-1", "G3HU77-1", "G3HAH5-1", "G3HJ88-1", "G3GSH5-1", "G3GY12-1", "G3I5T3-1", "G3I6L7-1", "G3H484-1", "G3IJD1-1", "G3I008-1", "A0A8C2M596-1", "G3IG24-1", "A0A9J7F876-1", "A0A9J7FI42-1", "A0A9J7G1N4-1", "A0A061IJA4-1", "A0A9J7FPD0-1", "A0A9J7G7V8-1", "A0A9J7JQY5-1", "A0A8C2MCA5-1", "A0A9J7H2D3-1", "A0A9J7G2T1-1", "G3HBU1-1", "G3HUZ6-1", "G3HWS4-1", "A0A9J7HCU3-1", "A0A3L7HMZ7-1", "A0A9J7K3T5-1", "A0A8C2MMI4-1", "A0A9J7GRQ0-1", "A0A8C2N055-1", "A0A8C2QHV1-1", "A0A8C2QM19-1", "A0A8C2M4F5-1", "A0A9J7FJ23-1", "A0A9J7FUH6-1", "A0A9J7G659-1", "A0A9J7K2R5-1", "A0A8C2MB35-1", "G3I478-1", "A0A9J7H1K5-1", "A0A8C2QH91-1", "A0A9J7JQ85-1", "A0A9J7K381-1", "A0A061HU45-1", "A0A061I456-1", "A0A061ICN7-1", "A0A061IKS3-1", "A0A3L7H9D4-1", "A0A9J7H2L4-1", "A0A8C2LZL3-1", "A0A8C2M796-1", "A0A8C2MCS3-1", "A0A8C2MPK3-1", 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}, { "uniprot_ac": "A0A8C2MCA5", "gene_name": "Ddx41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCA5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCA5" } ] } ] }, { "uniprot_ac": "A0A8C2MCS3", "gene_name": "Ddx47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MCS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCS3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MCS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCS3" } ] } ] }, { "uniprot_ac": "A0A8C2MFM1", "gene_name": "Vps4b", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFM1" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2MFM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFM1" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MPK3", "gene_name": "Mcm6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPK3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8C2MPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPK3" } ] } ] }, { "uniprot_ac": "A0A8C2MQ86", "gene_name": "Ddx50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MQ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ86" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MQ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ86" } ] } ] }, { "uniprot_ac": "A0A8C2MVH8", "gene_name": "Mcm7", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVH8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8C2MVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVH8" } ] } ] }, { "uniprot_ac": "A0A8C2MWE0", "gene_name": "Snrnp200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWE0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWE0" } ] } ] }, { "uniprot_ac": "A0A8C2MWH4", "gene_name": "Ddx25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MWH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MWH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWH4" } ] } ] }, { "uniprot_ac": "A0A8C2MYM8", "gene_name": "Tdrd9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYM8" } ] } ] }, { "uniprot_ac": "A0A8C2N055", "gene_name": "Ythdc2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N055" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2N055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N055" } ] } ] }, { "uniprot_ac": "A0A8C2N184", "gene_name": "Entpd8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8C2N184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N184" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8C2N184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N184" } ] } ] }, { "uniprot_ac": "A0A8C2N236", "gene_name": "Atp13a4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8C2N236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N236" } ] } ] }, { "uniprot_ac": "A0A8C2N386", "gene_name": "Vcp", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] } ] }, { "uniprot_ac": "A0A8C2QH91", "gene_name": "Ino80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8C2QH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH91" } ] } ] }, { "uniprot_ac": "A0A8C2QHV1", "gene_name": "Ddx20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] } ] }, { "uniprot_ac": "A0A8C2QLX9", "gene_name": "Ddx52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] } ] }, { "uniprot_ac": "A0A8C2QM19", "gene_name": "Clpx", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] } ] }, { "uniprot_ac": "A0A8C2QNE7", "gene_name": "Eif4a3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] } ] }, { "uniprot_ac": "A0A9J7F1E5", "gene_name": "Hltf", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] } ] }, { "uniprot_ac": "A0A9J7F876", "gene_name": "Ddx11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] } ] }, { "uniprot_ac": "A0A9J7F9W3", "gene_name": "Zgrf1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] } ] }, { "uniprot_ac": "A0A9J7FCH5", "gene_name": "Mov10l1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] } ] }, { "uniprot_ac": "A0A9J7FI19", "gene_name": "Xrcc6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] } ] }, { "uniprot_ac": "A0A9J7FI42", "gene_name": "Fbh1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FJ37", "gene_name": "Mcm9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] } ] }, { "uniprot_ac": "A0A9J7FPD0", "gene_name": "Dhx32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] } ] }, { "uniprot_ac": "A0A9J7FPK3", "gene_name": "Twnk", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] } ] }, { "uniprot_ac": "A0A9J7FTT2", "gene_name": "Mcm5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": 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Involved in DNA double-strand break repair and UV-damage excision repair.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601#function" }, { "database": "UniProtKB", "id": "ARBA00054422", "url": "https://www.uniprot.org/uniprotkb/ARBA00054422#function" }, { "database": "UniProtKB", "id": "A0A3L7HFY5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HFY5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Actr5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601", "locus": {} } ], "crossref": [ { "id": "A0A9J7G601", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G601", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765489", "url": "https://www.ncbi.nlm.nih.gov/gene/100765489", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765489", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765489", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G601", "url": "https://www.orthodb.org/?gene=A0A9J7G601", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277039", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277039", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HFY5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HFY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HFY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HFY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G601-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEANVFRFRDARAAPDPVLEAEPVAFGSQPVPLVLDNGSFQARAGWACPGPDPGPEPRLQFRAVCARGRGGARGGPGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYRIPKVAYGIDSLFSFYHNMPKNALSSGLIISSGYQCTHILPVLEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILQEHSYIAEDYGAELQKWRCPDYYENNVHKMQLPFSNKLLGSTLTAEEKQERRQQQLRRLQELNARRREEKLQLDQERLERLLYVQELLEDGQMDQFHKALIELNMDSPEELQSYIQKLTLAVEQAKQKILQAEANLEVDVVDSKPEVIPQQLHQSATTSLSCQSALLESSTPDLEQLEPSLEDVESINDFEPLFSEEAPEVEKPVTTVQPVFNLAAYHQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLHYVLDRYPKAVQDTLVQNVFLTGGNVMYPGMKARMEKELLEMRPFQSSFQVQLASNPVLDAWYGARDWALDHLEDSGAWVTRKDYEEKGGEYLKEHCASNTYVPIRLPKQASRASETQTSGRGSGASGSGAGEQA", "length": 631, "header": "tr|A0A9J7G601-1|A0A9J7G601_CRIGR Isoform 1 of Actin-related protein 5 OS=Cricetulus griseus OX=10029 GN=Actr5 PE=3 SV=1 CANONICAL=A0A9J7G601-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HFY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601/entry#A0A3L7HFY5-1", "sequence": { "sequence": "MEANVFRFRDARAAPDPVLEAEPVAFGSQPVPLVLDNGSFQARAGWACPGPDPGPEPRLQFRAVCARGRGGARGGPGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYRIPKVAYGIDSLFSFYHNMPKNALSSGLIISSGYQCTHILPVLEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILQEHSYIAEDYGAELQKWRCPDYYENNVHKMQLPFSNKLLGSTLTAEEKQERRQQQLRRLQELNARRREEKLQLDQERLERLLYVQELLEDGQMDQFHKALIELNMDSPEELQSYIQKLTLAVEQAKQKILQAEANLEVDVVDSKPETPDLEQLEPSLEDVESINDFEPLFSEEAPEVEKPVTTVQPVFNLAAYHQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLHYVLDRYPKAVQDTLVQNVFLTGGNVMYPGMKARMEKELLEMRPFQSSFQVQLASNPVLDAWYGARDWALDHLEDSGAWVTRKDYEEKGGEYLKEHCASNTYVPIRLPKQASRASETQTSGRGSGASGSGAGEQA", "length": 607, "header": "tr|A0A3L7HFY5-1|A0A3L7HFY5_CRIGR Computationally mapped isoform of Actin-related protein 5 OS=Cricetulus griseus OX=10029 GN=Actr5 PE=3 SV=1 CANONICAL=A0A9J7G601-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G601-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601/entry#A0A9J7G601-1", "sequence": { "sequence": "MEANVFRFRDARAAPDPVLEAEPVAFGSQPVPLVLDNGSFQARAGWACPGPDPGPEPRLQFRAVCARGRGGARGGPGPQVGNALGSLEPLRWMLRSPFDRNVPVNLELQELLLDYSFQHLGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLFECYRIPKVAYGIDSLFSFYHNMPKNALSSGLIISSGYQCTHILPVLEGRLDAKNCKRINLGGSQAAGYLQRLLQLKYPGHLAAITLSRMEEILQEHSYIAEDYGAELQKWRCPDYYENNVHKMQLPFSNKLLGSTLTAEEKQERRQQQLRRLQELNARRREEKLQLDQERLERLLYVQELLEDGQMDQFHKALIELNMDSPEELQSYIQKLTLAVEQAKQKILQAEANLEVDVVDSKPEVIPQQLHQSATTSLSCQSALLESSTPDLEQLEPSLEDVESINDFEPLFSEEAPEVEKPVTTVQPVFNLAAYHQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLHYVLDRYPKAVQDTLVQNVFLTGGNVMYPGMKARMEKELLEMRPFQSSFQVQLASNPVLDAWYGARDWALDHLEDSGAWVTRKDYEEKGGEYLKEHCASNTYVPIRLPKQASRASETQTSGRGSGASGSGAGEQA", "length": 631, "header": "tr|A0A9J7G601-1|A0A9J7G601_CRIGR Isoform 1 of Actin-related protein 5 OS=Cricetulus griseus OX=10029 GN=Actr5 PE=3 SV=1 CANONICAL=A0A9J7G601-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765489", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765489", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 13, "go_terms": [ { "name": "regulation of chromosome organization", "id": "GO:0033044", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033044", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "positive regulation of macromolecule metabolic process", "id": "GO:0010604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010604", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "regulation of DNA metabolic process", "id": "GO:0051052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051052", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "regulation of DNA strand elongation", "id": "GO:0060382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060382", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "double-strand break repair", "id": "GO:0006302", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006302", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "regulation of DNA replication", "id": "GO:0006275", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006275", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "UV-damage excision repair", "id": "GO:0070914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070914", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" }, { "name": "Ino80 complex", "id": "GO:0031011", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031011", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G601", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G601" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 37, "end_pos": 39 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620" } ] }, { "name": "Rpn2", "type": "synonym", "evidence": [ { "id": "XP_027277078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277078" } ] } ], "protein_names": [ { "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "type": "recommended", "evidence": [ { "id": "A0A9J7G620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620/entry#names_and_taxonomy" } ] }, { "name": "Ribophorin-2", "type": "synonym", "evidence": [ { "id": "A0A9J7G620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620/entry#names_and_taxonomy" } ] }, { "name": "dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027277078", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277078" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277078" } ] }, { "annotation": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G620", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620#function" }, { "database": "UniProtKB", "id": "RU366029", "url": "https://www.uniprot.org/uniprotkb/RU366029#function" }, { "database": "UniProtKB", "id": "ARBA00002791", "url": "https://www.uniprot.org/uniprotkb/ARBA00002791#function" }, { "database": "UniProtKB", "id": "A0A9J7G623", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G623#function" }, { "database": "UniProtKB", "id": "A0A9J7JRP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRP5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G620", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rpn2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620", "locus": {} } ], "crossref": [ { "id": "A0A9J7G620", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G620", "database": "AlphaFoldDB", "categories": [] }, { "id": "103158732", "url": "https://www.ncbi.nlm.nih.gov/gene/103158732", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008814", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008814", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103158732", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158732", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G620", "url": "https://www.orthodb.org/?gene=A0A9J7G620", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12640:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12640:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05817", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05817", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23860", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23860", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23861", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23861", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277078", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G620", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G620-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G623", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G623", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G623-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G623-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRP5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRP5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPGSSAVFLLALTIVATTQALTPTHYLTKHDVERLKASLDRPFTNLESAFYSIVGLNSLGAQVPDVKKACTFIKSNLDPSNVDSLFYAAQSSQVLSGCEISVSNETKDLLLAAVSEDSSVAQIYHAVAALSGFGLPLASHEALGALTARLSKEETVLATVQALQTASHLSQQADLRNIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSMKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAALSQNRYHIPVVVVPEGSASDTHEQAILRLQVSNVLSQPLTQAAVKLEHAKSVASRATTVLQKMPFTLAGDVFELNFKNVKLSSGYYDFSVKVEGDSRYIASTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVAYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTIIFHLGHAAMLGLMYVYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQQAVKRIAAEQSSRLAKYRTLRFPCQRKKANPSTPKF", "length": 660, "header": "tr|A0A9J7G620-1|A0A9J7G620_CRIGR Isoform 1 of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Cricetulus griseus OX=10029 GN=Rpn2 PE=3 SV=1 CANONICAL=A0A9J7G620-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G620-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620/entry#A0A9J7G620-1", "sequence": { "sequence": "MAPPGSSAVFLLALTIVATTQALTPTHYLTKHDVERLKASLDRPFTNLESAFYSIVGLNSLGAQVPDVKKACTFIKSNLDPSNVDSLFYAAQSSQVLSGCEISVSNETKDLLLAAVSEDSSVAQIYHAVAALSGFGLPLASHEALGALTARLSKEETVLATVQALQTASHLSQQADLRNIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSMKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAALSQNRYHIPVVVVPEGSASDTHEQAILRLQVSNVLSQPLTQAAVKLEHAKSVASRATTVLQKMPFTLAGDVFELNFKNVKLSSGYYDFSVKVEGDSRYIASTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVAYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTIIFHLGHAAMLGLMYVYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQQAVKRIAAEQSSRLAKYRTLRFPCQRKKANPSTPKF", "length": 660, "header": "tr|A0A9J7G620-1|A0A9J7G620_CRIGR Isoform 1 of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Cricetulus griseus OX=10029 GN=Rpn2 PE=3 SV=1 CANONICAL=A0A9J7G620-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G623-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620/entry#A0A9J7G623-1", "sequence": { "sequence": "MAPPGSSAVFLLALTIVATTQALTPTHYLTKHDVERLKASLDRPFTNLESAFYSIVGLNSLGAQVPDVKKACTFIKSNLDPSNVDSLFYAAQSSQVLSGCEISVSNETKDLLLAAVSEDSSVAQIYHAVAALSGFGLPLASHEALGALTARLSKEETVLATVQALQTASHLSQQADLRNIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSMKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAALSQNRYHIPVVVVPEGSASDTHEQAILRLQVSNVLSQPLTQAAVKLEHAKSVASRATTVLQKMPFTLAGDVFELNFKNVKLSSGYYDFSVKVEGDSRYIASTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVAYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTIIFHLGHAAMLGLMYVYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQQAVKRTAH", "length": 632, "header": "tr|A0A9J7G623-1|A0A9J7G623_CRIGR Computationally mapped isoform of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Cricetulus griseus OX=10029 GN=Rpn2 PE=3 SV=1 CANONICAL=A0A9J7G620-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620/entry#A0A9J7JRP5-1", "sequence": { "sequence": "MAPPGSSAVFLLALTIVATTQALTPTHYLTKHDVERLKASLDRPFTNLESAFYSIVGLNSLGAQVPDVKKACTFIKSNLDPSNVDSLFYAAQSSQVLSGCEISVSNETKDLLLAAVSEDSSVAQIYHAVAALSGFGLPLASHEALGALTARLSKEETVLATVQALQTASHLSQQADLRNIVEEIEDLVARLDELGGVYLQFEEGLETTALFVAATYKLMDHVGTEPSMKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAALSQNRYHIPVVVVPEGSASDTHEQAILRLQVSNVLSQPLTQAAVKLEHAKSVASRATTVLQKMPFTLAGDVFELNFKNVKLSSGYYDFSVKVEGDSRYIASTVELRVKISTEVGITNVDLSTVDKDQSIAPKTTRVAYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKNPILWNVADVVIKFPEEEAPSTVLSQNLFTPKQEIQHLFREPEKRPPTVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTIIFHLGHAAMLGLMYVYWTQLNMFQTLKYLAVLGTVTFLAGNRMLAQQAVKRIAAEQSSRLAKYRTLRTAH", "length": 648, "header": "tr|A0A9J7JRP5-1|A0A9J7JRP5_CRIGR Computationally mapped isoform of Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Cricetulus griseus OX=10029 GN=Rpn2 PE=3 SV=1 CANONICAL=A0A9J7G620-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G620", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G620", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103158732", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158732", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein N-linked glycosylation", "id": "GO:0006487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G620", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "oligosaccharyltransferase complex", "id": "GO:0008250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008250", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G620", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620" }, { "id": "PF25147", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25147" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribophorin II C-terminal", "eco_id": "ECO_0000259", "start_pos": 531, "end_pos": 629, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620" }, { "id": "PF05817", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05817" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribophorin II N-terminal", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 263, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620" }, { "id": "PF23861", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23861" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribophorin II second", "eco_id": "ECO_0000259", "start_pos": 271, "end_pos": 370, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G620", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G620" }, { "id": "PF23860", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23860" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribophorin II third", "eco_id": "ECO_0000259", "start_pos": 378, "end_pos": 503, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 570, "end_pos": 572 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G633-1", "uniprot_ac": "A0A9J7G633", "uniprot_id": "A0A9J7G633_CRIGR", "mass": { "chemical_mass": 14975.0, "monoisotopic_mass": 14975.0 }, "refseq": { "ac": "XP_027277099", "name": "LOW QUALITY PROTEIN: respirasome Complex Assembly Factor 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277099" }, "gene_names": [ { "name": "LOC100763162", "type": "recommended", "evidence": [ { "id": "A0A9J7G633", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G633" } ] }, { "name": "LOC100763162", "type": "synonym", "evidence": [ { "id": "XP_027277099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277099" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: respirasome Complex Assembly Factor 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027277099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277099" }, { "id": "A0A9J7G633", "database": 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277290" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tpx2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5", "locus": {} } ], "crossref": [ { "id": "100756732", "url": "https://www.ncbi.nlm.nih.gov/gene/100756732", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027329", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027329", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756732", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756732", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G6C5", "url": "https://www.orthodb.org/?gene=A0A9J7G6C5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14326", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14326", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14326:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14326:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277290", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277290", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G6C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JV09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JV09-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSQVTTTYSFDAPTNFINFSSLDAEEDTENVDSWFEEKANLGNKLLGKNGIEELFQGKTSLRKAKLQKSRVTPLKAVDNTYYNEAEKANLQKHSVPSDDCSVNAEGAVSGKTPVQAQRRSVRLSAKKDLEHKSKKHALVEMKAKRCTTPSSDFPPSKRIRMSHKKKPEEEEEDSVRGASRKNERESLEKVKGKHTAPGVPPARQKVLKSTEEQELEKRLKMQQEVVEMRRKNEEFKKLALAGPGQPVKKSVNQVTKTVDFHFLTDERIKQHPKNQEEYKEVNFMSELRKHPPSPVSCQARVTKGCTVVKPFNLSKGKKRTFDETASTYVPIAQQVEAFHKRTPNRYHLRNKKEENLLPSRTETKISRDPKTPILQTKYRARLVTCKSTAEQEAEELEKLQQYKFKARELDPRIFEGGPILPKRPPAKPPTQPVGFDLEIEKRIQDRESKKKSEDEHFEFHSRPCPTKILEDVVGVPEKKVIPATVPKSPVFALKNRIRVPTKEEEEEDKPVVIRAQPVPHYGVPYKPHIPEARNVEVCPFSFDTRDKERQLQKEKKIKEMQKGEVPKFKALPLPQFDTINLPEKKVKSVTQAEPFSLETDKRGAFKAEVWKLQLEEELKQQKEAACFKARPNTVIFQEPFVPKKKKPVAENLSGSLVQEEPFQLATERRAKERQELEKRMAEEEARKMQQLEEVRQQEEEQKKEELVKLRKELVHKANPIRKYAAVEVKSSELPLTVPVSPKFSTRFQ", "length": 748, "header": "tr|A0A9J7G6C5-1|A0A9J7G6C5_CRIGR Isoform 1 of Targeting protein for Xklp2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tpx2 PE=3 SV=1 CANONICAL=A0A9J7G6C5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G6C5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5/entry#A0A9J7G6C5-1", "sequence": { "sequence": "MSQVTTTYSFDAPTNFINFSSLDAEEDTENVDSWFEEKANLGNKLLGKNGIEELFQGKTSLRKAKLQKSRVTPLKAVDNTYYNEAEKANLQKHSVPSDDCSVNAEGAVSGKTPVQAQRRSVRLSAKKDLEHKSKKHALVEMKAKRCTTPSSDFPPSKRIRMSHKKKPEEEEEDSVRGASRKNERESLEKVKGKHTAPGVPPARQKVLKSTEEQELEKRLKMQQEVVEMRRKNEEFKKLALAGPGQPVKKSVNQVTKTVDFHFLTDERIKQHPKNQEEYKEVNFMSELRKHPPSPVSCQARVTKGCTVVKPFNLSKGKKRTFDETASTYVPIAQQVEAFHKRTPNRYHLRNKKEENLLPSRTETKISRDPKTPILQTKYRARLVTCKSTAEQEAEELEKLQQYKFKARELDPRIFEGGPILPKRPPAKPPTQPVGFDLEIEKRIQDRESKKKSEDEHFEFHSRPCPTKILEDVVGVPEKKVIPATVPKSPVFALKNRIRVPTKEEEEEDKPVVIRAQPVPHYGVPYKPHIPEARNVEVCPFSFDTRDKERQLQKEKKIKEMQKGEVPKFKALPLPQFDTINLPEKKVKSVTQAEPFSLETDKRGAFKAEVWKLQLEEELKQQKEAACFKARPNTVIFQEPFVPKKKKPVAENLSGSLVQEEPFQLATERRAKERQELEKRMAEEEARKMQQLEEVRQQEEEQKKEELVKLRKELVHKANPIRKYAAVEVKSSELPLTVPVSPKFSTRFQ", "length": 748, "header": "tr|A0A9J7G6C5-1|A0A9J7G6C5_CRIGR Isoform 1 of Targeting protein for Xklp2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tpx2 PE=3 SV=1 CANONICAL=A0A9J7G6C5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5/entry#A0A9J7JLH3-1", "sequence": { "sequence": "MSQVTTTYSFDAPTNFINFSSLDAEEDTENVDSWFEEKANLGNKLLGKNGIEELFQGKTSLRKAKLQKSRVTPLKAVDNTYYNEAEKANLQKHSVPSDDCSVNAEGAVSGKTPVQAQRRSVRLSAKKDLEHKSKKHALVEMKAKRCTTPSSDFPPSKRIRMSHKKKPEEEEEDSVRGASRKNERESLEKVKGKHTAPGVPPARQKVLKSTEEQELEKRLKMQQEVVEMRRKNEEFKKLALAGPGQPVKKSVNQVTKTVDFHFLTDERIKQHPKNQEEYKEVNFMSELRKHPPSPARVTKGCTVVKPFNLSKGKKRTFDETASTYVPIAQQVEAFHKRTPNRYHLRNKKEENLLPSRTETKISRDPKTPILQTKYRARLVTCKSTAEQEAEELEKLQQYKFKARELDPRIFEGGPILPKRPPAKPPTQPVGFDLEIEKRIQDRESKKKSEDEHFEFHSRPCPTKILEDVVGVPEKKVIPATVPKSPVFALKNRIRVPTKEEEEEDKPVVIRAQPVPHYGVPYKPHIPEARNVEVCPFSFDTRDKERQLQKEKKIKEMQKGEVPKFKALPLPQFDTINLPEKKVKSVTQAEPFSLETDKRGAFKAEVWKLQLEEELKQQKEAACFKARPNTVIFQEPFVPKKKKPVAENLSGSLVQEEPFQLATERRAKERQELEKRMAEEEARKMQQLEEVRQQEEEQKKEELVKLRKELVHKANPIRKYAAVEVKSSELPLTVPVSPKFSTRFQ", "length": 744, "header": "tr|A0A9J7JLH3-1|A0A9J7JLH3_CRIGR Computationally mapped isoform of Targeting protein for Xklp2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tpx2 PE=3 SV=1 CANONICAL=A0A9J7G6C5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JV09-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5/entry#A0A9J7JV09-1", "sequence": { "sequence": "MSQVTTTYSFDAPTNFINFSSLDAEEDTENVDSWFEEKANLGNKLLGKNGIEELFQGKTSLRKAKLQKSRVTPLKAVDNTYYNEAEKANLQKHSVPSDDCSVNAEGAVSGKTPVQAQRRSVRLSAKKDLEHKSKKHALVEMKAKRCTTPSSDFPPSKRIRMSHKKKPEEEEEDSVRGASRKNERESLEKVKGKHTAPGVPPARQKVLKSTEEQELEKRLKMQQEVVEMRRKNEEFKKLALAGPGQPVKKSVNQVTKTVDFHFLTDERIKQHPKNQEEYKEVNFMSELRKHPPSPVSCQARVTKGCTVVKPFNLSKGKKRTFDETASTYVPIAQQVEAFHKRTPNRYHLRNKKEENLLPSRTETKISRDPKTPILQTKYRARLVTCKSTAEQEAEELEKLQQYKFKARELDPRIFEGGPILPKRPPAKPPTQPVGFDLEIEKRIQDRESKKKSEDEHFEFHSRPCPTKILEDVVGVPEKKVIPATVPKSPVFALKNRIRVPTKEEEEEDKPVVIRAQPVPHYGVPYKPHIPEARNVEVCPFSFDTRDKERQLQKEKKIKEMQKGEVPKFKALPLPQFDTINLPEKKVKSVTQAEPFSLETDKRGAFKAEVWKLQLEEELKQQKEAACFKARPNTVIFQEPFVPKKKKPVAVQEEPFQLATERRAKERQELEKRMAEEEARKMQQLEEVRQQEEEQKKEELVKLRKELVHKANPIRKYAAVEVKSSELPLTVPVSPKFSTRFQ", "length": 741, "header": "tr|A0A9J7JV09-1|A0A9J7JV09_CRIGR Computationally mapped isoform of Targeting protein for Xklp2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Tpx2 PE=3 SV=1 CANONICAL=A0A9J7G6C5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756732", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756732", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6C5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G6C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" }, { "id": "PF09041", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aurora-A binding", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 67, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G6C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" }, { "id": "PF06886", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TPX2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 662, "end_pos": 736, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G6C5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6C5" }, { "id": "PF12214", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12214" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TPX2 central", "eco_id": "ECO_0000259", "start_pos": 367, "end_pos": 491, "start_aa": "Arg", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 651, "end_pos": 653 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G6D6-1", "uniprot_ac": "A0A9J7G6D6", "uniprot_id": "A0A9J7G6D6_CRIGR", "mass": { "chemical_mass": 76214.0, "monoisotopic_mass": 76214.0 }, "refseq": { "ac": "XP_027275932", "name": "tetratricopeptide repeat protein 30A1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275932" }, "gene_names": [ { "name": "LOC100751235", "type": "recommended", "evidence": [ { "id": "A0A9J7G6D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6D6" } ] }, { "name": "LOC100751235", "type": "synonym", "evidence": [ { "id": "XP_027275932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275932" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 30", "type": "recommended", "evidence": [ { "id": "A0A9J7G6D6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6D6/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 30A1", "type": "synonym", "evidence": [ { "id": "XP_027275932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275932" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275932" } ] }, { "annotation": "Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6D6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6D6#function" }, { "database": "UniProtKB", "id": "RU367070", "url": "https://www.uniprot.org/uniprotkb/RU367070#function" }, { "database": "UniProtKB", "id": "ARBA00002105", "url": "https://www.uniprot.org/uniprotkb/ARBA00002105#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6D6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6D6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100751235", "url": 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"Protein" ] } ], "sequence": { "sequence": "MAWQSSSKVPDGEFTAVVYRLVRDSRYSEAAQLLGAELQRSPRSRAGLSLLAYCYYRLQEFELAAECYEQLSQMHPELEQYRLYQAQALYKACLYPEATRVSFLVDNPTYQTRVLRLQAAIKYSEGDLPGARSLVEQLLCGEDSERENDPDSMVNLGCLLYKEGHYEAACSKFLAALQASGYQPDLSYNLALAYYSSRQYAPALKHIADIIEHGIRQHPELGVGLTTEGIDIRSVGNTTVLHQTALVEAFNLKAAIEYQLRNFEVAQETLTDMPPRAEEELDPVTLHNQALMNMDARPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYDFLDAMITCQTAPEEAFIKLDGLAGMLTEQLRRLTKQVQEARYSRDDEIIKKVVNEYDETLEKYIPVLMAQAKIYWNLENYSMVEKIFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKNYDNILSVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYGDPDKKIYHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYHKKLGTDTWYYAKRCFLSLLENMSKHMIVLCDTVIEECVQFLEHCEFFGRNIPAVIEQPLEEERMHTGKNTVTYESRQLKALIYEIIGWNM", "length": 661, "header": "tr|A0A9J7G6D6-1|A0A9J7G6D6_CRIGR Isoform 1 of Tetratricopeptide repeat protein 30 OS=Cricetulus griseus OX=10029 GN=LOC100751235 PE=3 SV=1 CANONICAL=A0A9J7G6D6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G6D6-1", "url": 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"phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613623.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007648491", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648491" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rin2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0", "locus": {} } ], "crossref": [ { "id": "cd10394", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10394", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16131", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16131", "database": "CDD", 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"https://www.uniprot.org/uniprotkb/A0A9J7G8E0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVWTMGARGLDKRGSFFKLIDTIASEIGELKREMVQTDISLGNGLEPSETHSMVRHKDDGYSEDKDGKACPRDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQNQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPPNSPPPHRPLSSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSPGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVNHSKHGNVALLGTKPTPIPPPRLKKQASFLEAEGSAKTLTACRPSRSPEPEPEPEPELGTAGHAGGAPPRDAPGDCTRAPPPGSESQPPPCHGGRQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLVELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDSEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEAPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGVIFQNGEDLTPS", "length": 901, "header": "tr|A0A9J7G8E0-1|A0A9J7G8E0_CRIGR Isoform 1 of Ras and Rab interactor 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rin2 PE=3 SV=1 CANONICAL=A0A9J7G8E0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G6D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0/entry#A0A9J7G6D8-1", "sequence": { "sequence": "MRIIAYLREEASMVRHKDDGYSEDKDGKACPRDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQNQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPPNSPPPHRPLSSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSPGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVNHSKHGNVALLGTKPTPIPPPRLKKQASFLEAEGSAKTLTACRPSRSPEPEPEPEPELGTAGHAGGAPPRDAPGDCTRAPPPGSESQPPPCHGGRQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLVELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDSEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEAPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGVIFQNGEDLTPS", "length": 860, "header": "tr|A0A9J7G6D8-1|A0A9J7G8E0_CRIGR Computationally mapped isoform of Ras and Rab interactor 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rin2 PE=3 SV=1 CANONICAL=A0A9J7G8E0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0/entry#A0A9J7G6I0-1", "sequence": { "sequence": "MFCSWPRTRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPPNSPPPHRPLSSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSPGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVNHSKHGNVALLGTKPTPIPPPRLKKQASFLEAEGSAKTLTACRPSRSPEPEPEPEPELGTAGHAGGAPPRDAPGDCTRAPPPGSESQPPPCHGGRQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLVELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDSEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEAPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGVIFQNGEDLTPS", "length": 731, "header": "tr|A0A9J7G6I0-1|A0A9J7G6I0_CRIGR Computationally mapped isoform of Ras and Rab interactor 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Rin2 PE=3 SV=1 CANONICAL=A0A9J7G8E0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0/entry#A0A9J7G8E0-1", "sequence": { "sequence": "MSVWTMGARGLDKRGSFFKLIDTIASEIGELKREMVQTDISLGNGLEPSETHSMVRHKDDGYSEDKDGKACPRDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQNQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPPNSPPPHRPLSSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSPGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVNHSKHGNVALLGTKPTPIPPPRLKKQASFLEAEGSAKTLTACRPSRSPEPEPEPEPELGTAGHAGGAPPRDAPGDCTRAPPPGSESQPPPCHGGRQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLVELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDSEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEAPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGVIFQNGEDLTPS", "length": 901, "header": "tr|A0A9J7G8E0-1|A0A9J7G8E0_CRIGR Isoform 1 of Ras and Rab interactor 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rin2 PE=3 SV=1 CANONICAL=A0A9J7G8E0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0/entry#A0A9J7GAX4-1", "sequence": { "sequence": "MDPFCILSMVRHKDDGYSEDKDGKACPRDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQNQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPPNSPPPHRPLSSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSPGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVNHSKHGNVALLGTKPTPIPPPRLKKQASFLEAEGSAKTLTACRPSRSPEPEPEPEPELGTAGHAGGAPPRDAPGDCTRAPPPGSESQPPPCHGGRQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLVELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDSEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEAPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKNDPYGVIFQNGEDLTPS", "length": 856, "header": "tr|A0A9J7GAX4-1|A0A9J7GAX4_CRIGR Computationally mapped isoform of Ras and Rab interactor 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Rin2 PE=3 SV=1 CANONICAL=A0A9J7G8E0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6D8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6D8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764316", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764316", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZCX2-1", "protein_name": "Ras and Rab interactor 2", "gene_name": "RIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALGTAHSLKAEQHHNPPSQASPDPRGESATPRRRCAEGSGSGPREEAVLSGAAPPRAPARPAAGCCRRLRSLRAGCARAACLSRLQALWLVRQRLEEQSLGAVGYASLQLCFWFGYICFGSEFKAFTGVFPGTMSCLTMKAHCRDKRGSFFKLIDTIASEIGELKQEMVQTDVMVEDEPADLRSLVKNMDNVSSEKKDVKGCPRDSGYDSLSNKLSILDKLLHTHPVWLQLGLNDAEATEILRAQPPGIFLVRKSSKLLKKVISLRLPGDCGSCLKEFAIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPHAIAAAKTEAELEEIAQLGLNFWSSPANSSPSDASAPRKPGPSDSASKDSRQLCLINGVHSIRTRTPLELECSQTNGALCFINPLFLKVHSQDVTGSLKRQSLKSQDVNGTERPRSPPPRPPPPSINSVLMSPQLSRTIKQASVPETVNHKKERDLDLLQSKPTPIPPPRLKKQAVSAEVEGGSSKPAAVIQPACNSVRVPAAADVVGETPPPQPAPTASKKPAVSSSESHVPWNGGRQRLSDMSISTSSSDSLDFDRSMPLFGYEGDTNSSLEDFEGESDQESMAPPLKPKKKRNSSFVLPKIVKSQLRKVSGVFSSFMTPEKRMIKKIAEMSRDKRTYFGCLVQDYISFLQENKECHVSSTDMLQTVRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHIEAMLKEFHTADGSWKQLKENLQLVRQRNPQELGVFVPTPDFVDVEKIKVKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRLYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQDVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVDNPKEYSLFLFVDDTWQQLTEDTYPQKIKAELHSRPQPQVFHFVYKRINSDPYSAIFQNDDSAS", "length": 1025 }, "evidence": [ { "id": "A0A9J7G8E0", "url": "https://omabrowser.org/oma/group/A0A9J7G8E0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LNS3-1", "protein_name": "Ras and Rab interactor 2", "gene_name": "Rin2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPEVLRTFYVSCWQRGWGSEESPACSRASLGEMSAWTMGARGLDKRGSFFKLIDTIASEIGELKREMVQTDVSLENGLEPSETYSMVRHKDGGYPEDKDGKTCPRDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPPNSPPPHRPLSSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSTGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVHHSKHGNVALLGTKPTPIPPPRLKKQASFLEAESSAKTLTACRPGRSPPEPELELEVEMGTAGHAGGAPPRDAPGDCTRAPPPDSESQPPPCHGARQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLMELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEDPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKSDPYGVIFQNGDDLTPS", "length": 935 }, "evidence": [ { "id": "A0A9J7G8E0", "url": "https://omabrowser.org/oma/group/A0A9J7G8E0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F662-1", "protein_name": "Ras and Rab interactor 2 isoform X1", "gene_name": "rin2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVEMMMQSCLMDRSSSFFKLIDTFSTEISELKQEMVQPAREPETEILQGLEGEVSGLFLQSSACAGVPGVRDSGYDSLRRRMSMLDRLMQTHSVWLLLSLSDDEARHILQPQPAGSFVVRRCYKLQKKVISLRMDSDTLIVRDFPVKESQYTFSLEGSGISFADLFRLVAFCCISRDVLPFTLKLPEAIASAKTPTDLEEVAKLGKGFWDSELCNKNKSSVSGETACDGSKQRLKRSPAVPFTRTPSELECSQSNGALCFINPLFLQTHQSNPSPKKQEPSPGDEGGGSQHHHRALHRTGQQQGDSSVFCRKTPSKPHISVSRSESERSPPPRPPPPRFGSSRSAVLRKQKTMPETVCWIKTPQEKTSLLGRLGSSFISLSPSSSPPKKFSKPILVPSARNKNSSGLLDADGIRCHMALDDQTIEDAVSWSLAKLSSRNPTAMENGSPAHEHCSTGRERLSDISISTSSSDSLDFSHSFPLPMEASPSKTDRPTGDSSQEEEEDDGINLESDQEVPSPFKSKKQNSAGTFVLPRALRGQLRKMSDVLNSLMTPERRAIRKIVEQSRDKGTYFGCLVQDYVSFLQENRGCHTSGLELLQTLRQFMTQMKSYLLQSSELDPPIESLIPEDQIDQVMEKAMHKCVLKPLKPVIEAALRDFQLSSGTMQQLKENLLLAKAKQPQEMGVDGARPPDPVAIEKIRHKFNNMCKMYSPEKKVSLLLSVCKLIYTIMENNSGRMYGADDFLPMLTYVMAQCDMPELDTEIQYMMELLDPSLLHGEGGYYLTSAYGAMSLIKNFQEDQAARELSSETRNTLHQWHRRRTTQRTTPSVDDFQNYLRVALQDASSGCTAKTLQVQPYATTEDVCQICADKFKISDPENYALFLLTEETTQQLTLDTHPQKIKAELHSRPQPQIFYFVYRQIQNFPVLSEQLDDNTSAN", "length": 938 }, "evidence": [ { "id": "A0A9J7G8E0", "url": "https://omabrowser.org/oma/group/A0A9J7G8E0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D684-1", "protein_name": "Ras and Rab interactor 2", "gene_name": "Rin2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAWTMGAQGLDKRGSFFKLIDTIASEIGELKREMVQTDISRENGLEPSETHSMVRHKDGGYSEDKDGKTCPRDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPLNSPPPHRPLPSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSTGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVNHSKHGNVALLGTKPTPIPPPRLKKQASFLEAESSAKTLTARRPSRRSEPEPELELELEMGTAGHAGGAPPRDAPGDCTRAPPPGSESQPPPCHGARQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLMELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEDPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKSDPYGVIFQNGEDLTPS", "length": 903 }, "evidence": [ { "id": "A0A9J7G8E0", "url": "https://omabrowser.org/oma/group/A0A9J7G8E0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8E0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 694, "end_pos": 696, "annotation": "n_glycosylation_sequon" }, { "start_pos": 785, "end_pos": 787, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G8E0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E0" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": 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"cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 299, "end_pos": 301 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 694, "end_pos": 696 }, { "start_pos": 785, "end_pos": 787 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G6E1-1", "uniprot_ac": "A0A9J7G6E1", "uniprot_id": "A0A9J7G6E1_CRIGR", "mass": { "chemical_mass": 79177.0, "monoisotopic_mass": 79177.0 }, "refseq": { "ac": "XP_027274089", "name": "zinc finger and BTB domain-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274089" }, "gene_names": [ { "name": "Zbtb1", "type": "recommended", "evidence": [ { "id": "A0A9J7G6E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ] }, { "name": "Zbtb1", "type": "synonym", "evidence": [ { "id": "XP_027274089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274089" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7G6E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027274089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274089" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274089" } ] }, { "annotation": "Acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1#function" }, { "database": "UniProtKB", "id": "ARBA00059022", "url": "https://www.uniprot.org/uniprotkb/ARBA00059022#function" }, { "database": "UniProtKB", "id": "A0A061HZ47", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ47#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zbtb1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1", "locus": {} } ], "crossref": [ { "id": "A0A9J7G6E1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G6E1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18192", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18192", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764453", "url": "https://www.ncbi.nlm.nih.gov/gene/100764453", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EDDWPEA", "url": "https://omabrowser.org/oma/group/EDDWPEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF42", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF42", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027274089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274089", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HZ47", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HZ47-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREPDEESLQLATFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHSYQNTARAYHRIVDIRDGKDSNIKAELGEKDSSKTFSAQTDKYREDASQAPDGSASTTASRKSTVESGMAGEEKSRAAETKRIIIKMEPEDIPTDEMKDFNIIKVTDKDCNESTDNDELEDEPEEPFYRYYVEEDVGIKKSGRKTLKPRMSVSVDERSGLESMRPPNNSSPIQEDTDNASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNAEEKMDMEENPDEQSEIRDMFVEMLDDFRDSHYQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARMNHTNNIDKGYDLFKVKTKALPQSSRKPSVVSSLGRACLFCYTTDNTDGQNLADLIIFNGL", "length": 694, "header": "tr|A0A9J7G6E1-1|A0A9J7G6E1_CRIGR Isoform 1 of Zinc finger and BTB domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Zbtb1 PE=4 SV=1 CANONICAL=A0A9J7G6E1-1" }, "isoforms": [ { "isoform_ac": "A0A061HZ47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1/entry#A0A061HZ47-1", "sequence": { "sequence": "MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREPDEESLQLATFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHSYQNTARAYHRIVDIRDGKDSNIKAELGEKDSSKTFSAQTDKYREDASQAPDGSASTTASRKSTVESGMAGEEKSRAAETKRIIIKMEPEDIPTDEMKDFNIIKVTDKDCNESTDNDELEDEPEEPFYRYYVEEDVGIKKSGRKTLKPRMSVSVDERSGLESMRPPNNSSPIQEDTDNASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNAEEKMDMEENPDEQSEIRDMFVEMLDDFRDSHYQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMASGEIGPSKPLEK", "length": 644, "header": "tr|A0A061HZ47-1|A0A061HZ47_CRIGR Computationally mapped isoform of Zinc finger and BTB domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Zbtb1 PE=4 SV=1 CANONICAL=A0A9J7G6E1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1/entry#A0A9J7G6E1-1", "sequence": { "sequence": "MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREPDEESLQLATFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHSYQNTARAYHRIVDIRDGKDSNIKAELGEKDSSKTFSAQTDKYREDASQAPDGSASTTASRKSTVESGMAGEEKSRAAETKRIIIKMEPEDIPTDEMKDFNIIKVTDKDCNESTDNDELEDEPEEPFYRYYVEEDVGIKKSGRKTLKPRMSVSVDERSGLESMRPPNNSSPIQEDTDNASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNAEEKMDMEENPDEQSEIRDMFVEMLDDFRDSHYQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARMNHTNNIDKGYDLFKVKTKALPQSSRKPSVVSSLGRACLFCYTTDNTDGQNLADLIIFNGL", "length": 694, "header": "tr|A0A9J7G6E1-1|A0A9J7G6E1_CRIGR Isoform 1 of Zinc finger and BTB domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Zbtb1 PE=4 SV=1 CANONICAL=A0A9J7G6E1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A480E3Y5-1", "protein_name": "Zinc finger and BTB domain-containing protein 1", "gene_name": "ZBTB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGSEASRWCAEPSSTVNTPHNREPDEESLQLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHSYQNTRSYHRIVDIRDGKDSNIKTEFGEKDSSKAFCAQTDKYRGDTSQAADDSTSTTGSRKSSTVETELASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDELEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSINADERGGLENMRPPNNSSPVQEDTENASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNAEEKMDMEENPDEQSEIRDMFVEMLDDFRDNHFQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSAGETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT", "length": 713 }, "evidence": [ { "id": "A0A9J7G6E1", "url": "https://omabrowser.org/oma/group/A0A9J7G6E1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MAZ0-1", "protein_name": "Zinc finger and BTB domain-containing protein 1", "gene_name": "ZBTB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGSEANRWCAEPSSTVNTPHNREPDEESLQLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHSYQNTRSYHRLVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTGSRKSSTVESELASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDELEDEAEEPFYRYYVEEDVSIKKSGRKTLKPRMSINADERGGLENMRPPNNSSPVQEDTENASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNAEEKMDMEENPDEQSEIRDMFVEMLDDFRDNHFQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDVFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSAGETICQVCFQIFPNNEQLEQHMDIHLYTCGICGAKFNLRKDMRSHYNAKHLKRT", "length": 713 }, "evidence": [ { "id": "A0A9J7G6E1", "url": "https://omabrowser.org/oma/group/A0A9J7G6E1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { 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"https://omabrowser.org/oma/group/A0A9J7G6E1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q672J3-1", "protein_name": "Zinc finger and BTB domain containing 1", "gene_name": "Zbtb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSRSACLLEVTTVGLTRGRTETDRPKSSSLVLNRCKQAHRQEMAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDTYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKILTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDSDCSSSKCSSSASSKHNSKMIFGVRMYEDTVARNGSEANRWSAEPSSTVNTPHNREPEEESLPLANFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHSYQSTARAYHRVVDARDGKDSAIKAELGDKGSPTAFSAHTDKYREDASQAPDDSASPTGSRKSTVESGTAGEEKSRAAETKRVVIKMEPEDVPADDMKDFTIVKVTEKDCNESTDNDELEDEPEEPFYRYYVEEDVGIKKSGRKTLKPRMSVGVDERGGLENMRPPNNSSPRQEDAENASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNTDEKMDMEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKGAVMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSGGETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT", "length": 757 }, "evidence": [ { "id": "A0A9J7G6E1", "url": "https://omabrowser.org/oma/group/A0A9J7G6E1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91VL9-1", "protein_name": "Zinc finger and BTB domain-containing protein 1", "gene_name": "Zbtb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSRQSSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHHREPEEESLQLANFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHSYQNTTRAYHRIVDIRDGKDSNIKAELAEKDSSKTFSAQPDKYREDANQAPDDSASTTGSRKSTVEAGIAGEEKSRATETKRIIIKMEPEDIPADDMKDFNIIKVTEKDCNESTDNDELEDEPEEPFYRYYVEEDVGIKKSGRKTLKPRMSISVDERGGLENMRPPNNTSPIQEDAENASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNADEKMDMEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKGAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSGGETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT", "length": 713 }, "evidence": [ { "id": "A0A9J7G6E1", "url": "https://omabrowser.org/oma/group/A0A9J7G6E1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y2K1-1", "protein_name": "Zinc finger and BTB domain-containing protein 1", "gene_name": "ZBTB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHSTAQLNLSNMKISAECFDLILQFMYLGKIMTAPSSFEQFKVAMNYLQLYNVPDCLEDIQDADCSSSKCSSSASSKQNSKMIFGVRMYEDTVARNGNEANRWCAEPSSTVNTPHNREADEESLQLGNFPEPLFDVCKKSSVSKLSTPKERVSRRFGRSFTCDSCGFGFSCEKLLDEHVLTCTNRHLYQNTRSYHRIVDIRDGKDSNIKAEFGEKDSSKTFSAQTDKYRGDTSQAADDSASTTGSRKSSTVESEIASEEKSRAAERKRIIIKMEPEDIPTDELKDFNIIKVTDKDCNESTDNDELEDEPEEPFYRYYVEEDVSIKKSGRKTLKPRMSVSADERGGLENMRPPNNSSPVQEDAENASCELCGLTITEEDLSSHYLAKHIENICACGKCGQILVKGRQLQEHAQRCGEPQDLTMNGLGNTEEKMDLEENPDEQSEIRDMFVEMLDDFRDNHYQINSIQKKQLFKHSACPFRCPNCGQRFETENLVVEHMSSCLDQDMFKSAIMEENERDHRRKHFCNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHMISHLSAGETICQVCFQIFPNNEQLEQHMDVHLYTCGICGAKFNLRKDMRSHYNAKHLKRT", "length": 713 }, "evidence": [ { "id": "A0A9J7G6E1", "url": "https://omabrowser.org/oma/group/A0A9J7G6E1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "K63-linked polyubiquitin modification-dependent protein binding", "id": "GO:0070530", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070530", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 14, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated immunity", "id": "GO:0002711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002711", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "chromatin 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polymerase II", "id": "GO:0042789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "translesion synthesis", "id": "GO:0019985", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019985", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "positive regulation of pro-T cell differentiation", "id": "GO:2000176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000176", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6E1" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell differentiation", "id": "GO:0032825", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032825", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6E1", "url": 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{ "start_pos": 409, "end_pos": 411 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, 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"url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645730", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2NAT6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NAT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2NAT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NAT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6M7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6N4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISNHRHLHLTLASIHQQTHRIDATLTYRELAPRVQGKVLRPILLSAYSPRASISQLAPYFGAIMYHLPVHLDCGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNDSEPWQPSLNSEAVYPMNCVPDVITASKAGVSSALPPVDVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSSQPTPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPSTLANSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTNRGNGFDRNAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDDHRQLLAHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTGRHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSITQKELDMYVEWNKMFGCSQ", "length": 825, "header": 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OS=Cricetulus griseus OX=10029 GN=Fign PE=3 SV=1 CANONICAL=A0A9J7G6N4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6N4/entry#A0A9J7G6N4-1", "sequence": { "sequence": "MISNHRHLHLTLASIHQQTHRIDATLTYRELAPRVQGKVLRPILLSAYSPRASISQLAPYFGAIMYHLPVHLDCGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNDSEPWQPSLNSEAVYPMNCVPDVITASKAGVSSALPPVDVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYSSQPTPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPSTLANSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTNRGNGFDRNAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDDHRQLLAHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVSEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTGRHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSITQKELDMYVEWNKMFGCSQ", "length": 825, "header": "tr|A0A9J7G6N4-1|A0A9J7G6N4_CRIGR Isoform 1 of Fidgetin OS=Cricetulus griseus OX=10029 GN=Fign PE=3 SV=1 CANONICAL=A0A9J7G6N4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 269, "start_aa": "Thr", "end_pos": 269, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr269", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6M7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751083", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751083", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "microtubule severing ATPase activity", "id": "GO:0008568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008568", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6N4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6N4" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6N4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6N4" } ], "pmid": "" }, { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6N4" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": 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"tr|A0A9J7G6Q5-1|A0A9J7G6Q5_CRIGR Isoform 1 of Phospholipase A2 OS=Cricetulus griseus OX=10029 GN=Pla2g4e PE=4 SV=1 CANONICAL=A0A9J7G6Q5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G6Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5/entry#A0A9J7G6Q5-1", "sequence": { "sequence": "MLQNQMPAWVSHSLPDPCQAEDGRYLASCALKEGPSPCHLLTVRVIGMKNVRQADMLSQTDCFVTLWLPTASQEKLRTRTISNCLHPQWDESFTFQIQTQVKNVLELSVCDEDTLTPNDHLLTVLYDLSKLCLRNKTHVKFPLNPEGMEELEVEFLLAENLSSPEMLITNGVIVSRQVSCLEVHAESRRPRKRKKNKDLLVMVTDSFENTQRVPPCLEPCCDNLACFHYPMYFQPQLHVEAPESHWSCGLCCCGTRRNGPVSQPLDCLSDGQAVTLPVGENYELHMKSTPCPNTLDVRLGFSLCQEEVEFLQKRKVVVTKALSQVLQLEEDLHEDEVPLIAIMATGGGARSMVALYGHLMGLQKLNLLDCSTYITGLSGATWTMATLYSDAEWSSKNLEPAVFEARRHVVKDKMPALYPDQLCKWREELHQHNQEGYKTTLTDFWGKLIEYSLGDKKNDCKLSEQRAALCQGQNPLPIYLTINVKDDVSNQDFREWFEFSPYEVGMQKYGAFIPTELFGSEFFMGRLMKRIPEPEMCYMLGLWSSIFSLNLLDAWNLSHTSEEFYYRWIREKHHDIEDDPLLPEIPRCNDASPLETRVVIPASWLSNTFREILTHRSFVSEFHNFLYGMQLHTDYLQNKQFSMWKDTVLDTFPNQLTQFTKHLNLLDTAFFVNSSYAPLLRPERKIDLIIHLNYCAGSQTKPLKQTCEYCTTQNIPFPSYSIQEDDKSLKECYLMENPQEPDTPIVAYFPLINDTFQKYKAPGVERSPEELEQGQLNIYGPKSPYATKELTYTEAAFDKLVKLTEYNILNNKDKLIQAVRLAVEKKRMNRQCPS", "length": 834, "header": "tr|A0A9J7G6Q5-1|A0A9J7G6Q5_CRIGR Isoform 1 of Phospholipase A2 OS=Cricetulus griseus OX=10029 GN=Pla2g4e PE=4 SV=1 CANONICAL=A0A9J7G6Q5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770894", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770894", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycerophospholipid catabolic process", "id": "GO:0046475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046475", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15801", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7GN25-1", "G3GWV5-1", "G3HKV9-1", "G3HU37-1", "G3I6R7-1", "G3I3H3-1", "G3H0N8-1", "A0A9J7EWD9-1", "A0A9J7FZ00-1", "A0A9J7FZ10-1", "A0A9J7FZ67-1", "A0A9J7JIA7-1", "A0A9J7JN73-1", "A0A9J7JR59-1", "A0A061IDH0-1", "A0A8C2M3H3-1", "A0A9J7K9A2-1", "A0A9J7G6Q5-1", "A0A9J7G6Z0-1", "A0A3L7I2I8-1", "A0A9J7JL35-1", "A0A061IFI5-1", "A0A8C2LJA1-1", "A0A8C2LLB0-1", "A0A9J7FGH3-1", "A0A9J7G9Q8-1", "A0A9J7J6R6-1", "A0A3L7I8N6-1", "A0A8C2LBB3-1", "A0A8C2LXP3-1", "A0A8C2LZI5-1" ], "evidence": [ { "id": "15801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15801" } ] }, { "id": "40427", "name": "", "equation": "1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GWV5-1", "G3I6R7-1", "G3H0N8-1", "A0A9J7EWD9-1", "A0A9J7FZ00-1", "A0A9J7FZ10-1", "A0A9J7FZ67-1", "A0A9J7JIA7-1", "A0A9J7JN73-1", "A0A9J7JR59-1", "A0A9J7K9A2-1", "A0A9J7G6Z0-1", "A0A9J7G6Q5-1", "A0A3L7I2I8-1", "A0A9J7JL35-1", "A0A9J7FGH3-1", "A0A8C2LZI5-1" ], "evidence": [ { "id": "40427", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40427" } ] }, { "id": "40435", "name": "", "equation": "1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GWV5-1", "G3HKV9-1", "G3H0N8-1", "A0A3L7I8J4-1", "A0A8C2MCD7-1", "A0A9J7K9A2-1", "A0A9J7FM40-1", "A0A9J7JI58-1", "A0A9J7G7U0-1", "A0A9J7G6Q5-1", "A0A9J7G6Z0-1", "A0A3L7I2I8-1", "A0A9J7JL35-1", "A0A9J7FGH3-1", "A0A9J7G8F0-1", "A0A9J7G9Q8-1", "A0A9J7JFH6-1" ], "evidence": [ { "id": "40435", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40435" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061IDH0", "gene_name": "Pla2g2e", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A061IDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IDH0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A061IDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IDH0" } ] } ] }, { "uniprot_ac": "A0A061IFI5", "gene_name": "LOC113833875", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A061IFI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IFI5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A061IFI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IFI5" } ] } ] }, { "uniprot_ac": "A0A3L7I2I8", "gene_name": "PLA2G6", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A3L7I2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2I8" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3L7I2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2I8" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3L7I2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2I8" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A3L7I2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2I8" } ] } ] }, { "uniprot_ac": 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"A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] } ] }, { "uniprot_ac": "A0A8C2LLB0", "gene_name": "Pla2g10", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8C2LLB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLB0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8C2LLB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLB0" } ] } ] }, { "uniprot_ac": "A0A8C2LXP3", "gene_name": 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"uniprot_ac": "A0A8C2M3H3", "gene_name": "Pla2g2c", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8C2M3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3H3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8C2M3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3H3" } ] } ] }, { "uniprot_ac": "A0A8C2MCD7", "gene_name": "Lypla1", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A8C2MCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCD7" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A8C2MCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCD7" } ] } ] }, { "uniprot_ac": "A0A9J7EWD9", "gene_name": "Pla2g3", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7EWD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EWD9" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7EWD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EWD9" } ] } ] }, { "uniprot_ac": "A0A9J7FGH3", "gene_name": "Pla2g6", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] } ] }, { "uniprot_ac": "A0A9J7FM40", "gene_name": "LOC100764608", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A9J7FM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM40" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A9J7FM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM40" } ] } ] }, { "uniprot_ac": "A0A9J7FZ00", "gene_name": "LOC100765177", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FZ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ00" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7FZ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ00" } ] } ] }, { "uniprot_ac": "A0A9J7FZ10", "gene_name": "LOC113835677", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FZ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ10" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7FZ10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ10" } ] } ] }, { "uniprot_ac": "A0A9J7FZ67", "gene_name": "LOC100766341", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FZ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ67" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7FZ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ67" } ] } ] }, { "uniprot_ac": "A0A9J7G6Q5", "gene_name": "Pla2g4e", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G6Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7G6Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ] } ] }, { "uniprot_ac": "A0A9J7G6Z0", "gene_name": "Pla2g4d", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ] } ] }, { "uniprot_ac": "A0A9J7G7U0", "gene_name": "Pnpla7", "activity": [ { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G7U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7U0" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7G7U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7U0" } ] } ] }, { "uniprot_ac": "A0A9J7G8F0", "gene_name": "Cel", "activity": [ { "ec_number": "3.1.1.-", "activity": "", "evidence": [ { "id": "A0A9J7G8F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F0" } ] } ] }, { "uniprot_ac": "A0A9J7G9Q8", "gene_name": "Plb1", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] } ] }, { "uniprot_ac": "A0A9J7GN25", "gene_name": "Pla2g5", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7GN25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN25" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7GN25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN25" } ] } ] }, { "uniprot_ac": "A0A9J7J6R6", "gene_name": "Pnpla3", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] } ] }, { "uniprot_ac": "A0A9J7JFH6", "gene_name": "Lipc", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] } ] }, { "uniprot_ac": "A0A9J7JI58", "gene_name": "Pnpla6", "activity": [ { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI58" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7JI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI58" } ] } ] }, { "uniprot_ac": "A0A9J7JIA7", "gene_name": "LOC100763432", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JIA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIA7" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7JIA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIA7" } ] } ] }, { "uniprot_ac": "A0A9J7JL35", "gene_name": "Pla2g4b", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JL35" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7JL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JL35" } ] } ] }, { "uniprot_ac": "A0A9J7JN73", "gene_name": "LOC100765466", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JN73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN73" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7JN73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN73" } ] } ] }, { "uniprot_ac": "A0A9J7JR59", "gene_name": "LOC100752205", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR59" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7JR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR59" } ] } ] }, { "uniprot_ac": "A0A9J7K9A2", "gene_name": "Pla2g4f", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277952" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G701", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G701" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Itpka", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G701", "locus": {} } ], "crossref": [ { "id": "A0A9J7G701", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G701", "database": "AlphaFoldDB", "categories": [] }, { "id": "100772914", "url": "https://www.ncbi.nlm.nih.gov/gene/100772914", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005522", 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G742-1", "uniprot_ac": "A0A9J7G742", "uniprot_id": "A0A9J7G742_CRIGR", "mass": { "chemical_mass": 53956.0, "monoisotopic_mass": 53956.0 }, "refseq": { "ac": "XP_027278035", "name": "homeobox protein Meis2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278035" }, "gene_names": [ { "name": "Meis2", "type": "recommended", "evidence": [ { "id": "A0A9J7G742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742" } ] }, { "name": "Meis2", "type": "synonym", "evidence": [ { "id": "XP_027278035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278035" } ] } ], "protein_names": [ { "name": "Homeobox protein Meis2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7G742", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#names_and_taxonomy" } ] }, { "name": "homeobox protein Meis2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027278035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278035" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278035" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Meis2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742", "locus": {} } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764044", "url": "https://www.ncbi.nlm.nih.gov/gene/100764044", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764044", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764044", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G742", "url": "https://www.orthodb.org/?gene=A0A9J7G742", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11850", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11850", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278035", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MET9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MET9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MET9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MET9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MEU9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MEU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MM43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MM43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MM43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G742-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G783", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G783", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G783-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G783-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G983", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G983", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G983-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G983-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G988", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G988", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G988-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G988-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAR1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNIPNATQLGKSQEEWWGNKLEYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ", "length": 496, "header": "tr|A0A9J7G742-1|A0A9J7G742_CRIGR Isoform 1 of Homeobox protein Meis2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MET9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A8C2MET9-1", "sequence": { "sequence": "MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM", "length": 394, "header": "tr|A0A8C2MET9-1|A0A8C2MET9_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X11 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MEU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A8C2MEU9-1", "sequence": { "sequence": "MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ", "length": 477, "header": "tr|A0A8C2MEU9-1|A0A8C2MEU9_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MM43-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A8C2MM43-1", "sequence": { "sequence": "MFLYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM", "length": 400, "header": "tr|A0A8C2MM43-1|A0A8C2MM43_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X10 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A9J7G6U9-1", "sequence": { "sequence": "MPNIPNATQLGKSQEEWWGNKLEYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ", "length": 489, "header": "tr|A0A9J7G6U9-1|A0A9J7G742_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G742-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A9J7G742-1", "sequence": { "sequence": "MPNIPNATQLGKSQEEWWGNKLEYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ", "length": 496, "header": "tr|A0A9J7G742-1|A0A9J7G742_CRIGR Isoform 1 of Homeobox protein Meis2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G783-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A9J7G783-1", "sequence": { "sequence": "MPNIPNATQLGKSQEEWWGNKLEYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM", "length": 413, "header": "tr|A0A9J7G783-1|A0A9J7G783_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X8 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A9J7G7G0-1", "sequence": { "sequence": "MFLYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM", "length": 393, "header": "tr|A0A9J7G7G0-1|A0A9J7G7G0_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X12 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G983-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A9J7G983-1", "sequence": { "sequence": "MFLYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ", "length": 469, "header": "tr|A0A9J7G983-1|A0A9J7G983_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G988-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A9J7G988-1", "sequence": { "sequence": "MPNIPNATQLGKSQEEWWGNKLEYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM", "length": 420, "header": "tr|A0A9J7G988-1|A0A9J7G988_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X7 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A9J7GAR1-1", "sequence": { "sequence": "MFLYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ", "length": 476, "header": "tr|A0A9J7GAR1-1|A0A9J7GAR1_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A9J7GBT8-1", "sequence": { "sequence": "MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAGFLLDPSVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM", "length": 401, "header": "tr|A0A9J7GBT8-1|A0A9J7GBT8_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X9 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742/entry#A0A9J7JVS4-1", "sequence": { "sequence": "MAQRYDELPHYGGMDGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPNVMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAGGDVCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSWRDHDDATSTHSAGTPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTGDDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQLRHGPPMHSYLPSHPHHPAMMMHGGPPTHPGMTMSAQSPTMLNSVDPNVGGQVMDIHAQ", "length": 470, "header": "tr|A0A9J7JVS4-1|A0A9J7JVS4_CRIGR Computationally mapped isoform of Homeobox protein Meis2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Meis2 PE=3 SV=1 CANONICAL=A0A9J7G742-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6U9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6U9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6U9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764044", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764044", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of mitotic cell cycle", "id": "GO:0045931", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045931", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742" } ], "pmid": "" }, { "name": "positive regulation of cardiac muscle myoblast proliferation", "id": "GO:0110024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110024", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742" } ], "pmid": "" }, { "name": "negative regulation of myeloid cell differentiation", "id": "GO:0045638", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045638", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G742", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G742" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G6V9-1", "uniprot_ac": "A0A9J7G6V9", "uniprot_id": "A0A9J7G6V9_CRIGR", "mass": { "chemical_mass": 40081.0, "monoisotopic_mass": 40081.0 }, "refseq": { "ac": "XP_027274483", "name": "proton-activated chloride channel isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274483" }, "gene_names": [ { "name": "Pacc1", "type": "recommended", "evidence": [ { "id": "A0A9J7G6V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9" } ] }, { "name": "Pacc1", "type": "synonym", "evidence": [ { "id": "XP_027274483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274483" } ] } ], "protein_names": [ { "name": "Proton-activated chloride channel", "type": "recommended", "evidence": [ { "id": "A0A9J7G6V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 206", "type": "synonym", "evidence": [ { "id": "A0A9J7G6V9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9/entry#names_and_taxonomy" } ] }, { "name": "proton-activated chloride channel isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027274483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274483" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274483" } ] }, { "annotation": "Chloride channel gated by pH that facilitates the entry of chloride ions into cells upon exposure to extracellular acidic pH. Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9#function" }, { "database": "UniProtKB", "id": "ARBA00045384", "url": "https://www.uniprot.org/uniprotkb/ARBA00045384#function" }, { "database": "UniProtKB", "id": "A0A9J7K991", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K991#function" }, { "database": "UniProtKB", "id": "A0A8C2LIT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIT7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pacc1", 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"https://www.uniprot.org/uniprotkb/A0A9J7G6V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K991", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K991", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K991-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K991-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIRQDLSTSYQELSEELDQVVENSEQADERDKEPVQVQGPGVLPAGVDSESASSTIRFSKACLKNVFSVLLILIYLLLMAVAVFLVYQTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHYEVIPPLASPGQPGDRNCTTQRVNYTNPFSNHTMQSALIVQGPQDVRKRELVFLQFRLSQSNEDFSAIDYLLFSSFQEFMRSSDKAGFMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQETSVVNYIDQRPAAEKNTQLFFVVFEWKDPFIQKVQDIITANPWNTIALLCGAFLALFKAAEFAKLSVKWMIKIRKRYLKRRGQATNHIS", "length": 351, "header": "tr|A0A9J7G6V9-1|A0A9J7G6V9_CRIGR Isoform 1 of Proton-activated chloride channel OS=Cricetulus griseus OX=10029 GN=Pacc1 PE=3 SV=1 CANONICAL=A0A9J7G6V9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LIT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9/entry#A0A8C2LIT7-1", "sequence": { "sequence": "MIRQDLSTSYQELSEELDQVVENSEQADERDKEPVQVQGPGVLPGVDSESASSTIRFSKACLKNVFSVLLILIYLLLMAVAVFLVYQTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHYEVIPPLASPGQPGDRNCTTQRVNYTNPFSNHTMQSALIVQGPQDVRKRELVFLQFRLSQSNEDFSAIDYLLFSSFQEFMRSSDKAGFMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQETSVVNYIDQRPAAEKNTQLFFVVFEWKDPFIQKVQDIITANPWNTIALLCGAFLALFKAAEFAKLSVKWMIKIRKRYLKRRGQATNHIS", "length": 350, "header": "tr|A0A8C2LIT7-1|A0A8C2LIT7_CRIGR Computationally mapped isoform of Proton-activated chloride channel OS=Cricetulus griseus OX=10029 GN=Pacc1 PE=3 SV=1 CANONICAL=A0A9J7G6V9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9/entry#A0A9J7G6V9-1", "sequence": { "sequence": "MIRQDLSTSYQELSEELDQVVENSEQADERDKEPVQVQGPGVLPAGVDSESASSTIRFSKACLKNVFSVLLILIYLLLMAVAVFLVYQTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHYEVIPPLASPGQPGDRNCTTQRVNYTNPFSNHTMQSALIVQGPQDVRKRELVFLQFRLSQSNEDFSAIDYLLFSSFQEFMRSSDKAGFMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQETSVVNYIDQRPAAEKNTQLFFVVFEWKDPFIQKVQDIITANPWNTIALLCGAFLALFKAAEFAKLSVKWMIKIRKRYLKRRGQATNHIS", "length": 351, "header": "tr|A0A9J7G6V9-1|A0A9J7G6V9_CRIGR Isoform 1 of Proton-activated chloride channel OS=Cricetulus griseus OX=10029 GN=Pacc1 PE=3 SV=1 CANONICAL=A0A9J7G6V9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K991-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9/entry#A0A9J7K991-1", "sequence": { "sequence": "MIRQDLSTSYQELSEELDQVVENSEQADERDKEPVQVQGPGVLPGVDSESASSTIRFSKACLKNVFSVLLILIYLLLMAVAVFLVYQTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHYEVIPPLASPGQPGDRNCTTQRVNYTNPFSNHTMQSALIVQGPQDVRKRELVFLQFRLSQSNEDFSAIDYLLFSSFQEFMRRPAWLIILTRGLLPRKTLSCSLWSSNGKIPSSRRSRM", "length": 249, "header": "tr|A0A9J7K991-1|A0A9J7K991_CRIGR Computationally mapped isoform of Proton-activated chloride channel OS=Cricetulus griseus OX=10029 GN=Pacc1 PE=3 SV=1 CANONICAL=A0A9J7G6V9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764103", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764103", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9" } ], "pmid": "" }, { "name": "chloride channel complex", "id": "GO:0034707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034707", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chloride channel activity", "id": "GO:0005254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005254", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9" } ], "pmid": "" }, { "name": "pH-gated chloride channel activity", "id": "GO:0061797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061797", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6V9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6V9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29823", "name": "", "equation": "chloride(in) = chloride(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7K381-1" ], "evidence": [ { "id": "29823", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29823" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7K381", "gene_name": "Cftr", "activity": [ { "ec_number": "5.6.1.6", "activity": "ATP + H2O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel.", "evidence": [ { "id": "A0A9J7K381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K381" } ] }, { "ec_number": "5.6.1.6", "activity": "", "evidence": [ { "id": "A0A9J7K381", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K381" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 163, "end_pos": 165 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262029" }, "gene_names": [ { "name": "Pla2g4d", "type": "recommended", "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ] }, { "name": "Pla2g4d", "type": "synonym", "evidence": [ { "id": "XP_027262029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262029" } ] } ], "protein_names": [ { "name": "Phospholipase A2", "type": "recommended", "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.4", "type": "synonym", "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0/entry#names_and_taxonomy" } ] }, { "name": "cytosolic phospholipase A2 delta", "type": "synonym", "evidence": [ { "id": "XP_027262029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262029" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027262029.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262029" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pla2g4d", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0", "locus": {} } ], "crossref": [ { "id": "A0A9J7G6Z0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G6Z0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04036", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04036", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103158591", "url": 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"id": "cge:103158591", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158591", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G6Z0", "url": "https://www.orthodb.org/?gene=A0A9J7G6Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10728", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10728", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10728:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10728:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18695", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18695", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262029", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "15801", "url": "https://www.rhea-db.org/rhea/15801", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40427", "url": "https://www.rhea-db.org/rhea/40427", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "40435", "url": "https://www.rhea-db.org/rhea/40435", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDEMPEVPADFPGLHRWPSWRPSVINAELHATGRRASLGAQEEAAVFWKLTVKILEARSLPRADLLSKADPYVTLLLPTAPGMKFKTKTVTNSSHPVWNETFNFLIQSQVKNILELTIYDEDLIVKDDICFKVSYDVSEILPGQLLQKTFRLNPQGPEELDVEFLMEKLLDPPENLITNNVLVARELSRLDVCLDRVGSTTMAAGQEKLELELVLKGSYEDTQTFALDTASTFSFHYLRGQDTELSGCLRSSRNSGWNSNTSTIPFNVPLKSLTTGKEVTVDIPATNVPEVKLQLKTDCCPQELAVRLGCGLCPEEQAFLGRRKQVVAAALKQALQLDEDLKEDEVPVVGIMAEGGGVRAMVSLYGHLLALQKLGLLDCVTYFSGISGSTWTMAHLYQDPEWSQKDLDGPISHAREHVAKSLWREFSPEHLASYHQALKLRAEQGHTTTIADLWGLVLESKLHGQVTDQKLSGQRAALERGQNPLPLYLSLNVKENNLDTLHFKEWVEFSPYEVGFLKYGGFVTPELFGSEFFMGRLMKRLPESQICFLEGIWSNIFSVNLMDIWYDVTSGKDWKNAIVDVQNSEESSALAGTSSYVEASWLQPGTALAQAFKGFLSGRPFHQCSANFLRGLQLHRDYRNQKDFSTWADCHLDNTPNQLTPQDTQLCLVDAAYFINNSCPSMLRPGRQVDLILSFNYSQFSPFEGLQQSETYCRAQGLPFPHVEPSPEDQRQPQECHLFSDPTCPEAPVLLHFPLVNGSFRDHSAPGVRRSPDELKAGLVDLTGEDSPYILYNMTYKEEDFDRLLQLTDYNIRNSQDTILQALKTVLKRRAPEAKPSGMQT", "length": 842, "header": "tr|A0A9J7G6Z0-1|A0A9J7G6Z0_CRIGR Isoform 1 of Phospholipase A2 OS=Cricetulus griseus OX=10029 GN=Pla2g4d PE=4 SV=1 CANONICAL=A0A9J7G6Z0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G6Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0/entry#A0A9J7G6Z0-1", "sequence": { "sequence": "MVDEMPEVPADFPGLHRWPSWRPSVINAELHATGRRASLGAQEEAAVFWKLTVKILEARSLPRADLLSKADPYVTLLLPTAPGMKFKTKTVTNSSHPVWNETFNFLIQSQVKNILELTIYDEDLIVKDDICFKVSYDVSEILPGQLLQKTFRLNPQGPEELDVEFLMEKLLDPPENLITNNVLVARELSRLDVCLDRVGSTTMAAGQEKLELELVLKGSYEDTQTFALDTASTFSFHYLRGQDTELSGCLRSSRNSGWNSNTSTIPFNVPLKSLTTGKEVTVDIPATNVPEVKLQLKTDCCPQELAVRLGCGLCPEEQAFLGRRKQVVAAALKQALQLDEDLKEDEVPVVGIMAEGGGVRAMVSLYGHLLALQKLGLLDCVTYFSGISGSTWTMAHLYQDPEWSQKDLDGPISHAREHVAKSLWREFSPEHLASYHQALKLRAEQGHTTTIADLWGLVLESKLHGQVTDQKLSGQRAALERGQNPLPLYLSLNVKENNLDTLHFKEWVEFSPYEVGFLKYGGFVTPELFGSEFFMGRLMKRLPESQICFLEGIWSNIFSVNLMDIWYDVTSGKDWKNAIVDVQNSEESSALAGTSSYVEASWLQPGTALAQAFKGFLSGRPFHQCSANFLRGLQLHRDYRNQKDFSTWADCHLDNTPNQLTPQDTQLCLVDAAYFINNSCPSMLRPGRQVDLILSFNYSQFSPFEGLQQSETYCRAQGLPFPHVEPSPEDQRQPQECHLFSDPTCPEAPVLLHFPLVNGSFRDHSAPGVRRSPDELKAGLVDLTGEDSPYILYNMTYKEEDFDRLLQLTDYNIRNSQDTILQALKTVLKRRAPEAKPSGMQT", "length": 842, "header": "tr|A0A9J7G6Z0-1|A0A9J7G6Z0_CRIGR Isoform 1 of Phospholipase A2 OS=Cricetulus griseus OX=10029 GN=Pla2g4d PE=4 SV=1 CANONICAL=A0A9J7G6Z0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103158591", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158591", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ], "pmid": "" }, { "name": "phospholipase A2 activity", "id": "GO:0004623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004623", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glycerophospholipid catabolic process", "id": "GO:0046475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046475", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" }, { "start_pos": 794, "end_pos": 796, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "15801", "name": "", "equation": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7GN25-1", "G3GWV5-1", "G3HKV9-1", "G3HU37-1", "G3I6R7-1", "G3I3H3-1", "G3H0N8-1", "A0A9J7EWD9-1", "A0A9J7FZ00-1", "A0A9J7FZ10-1", "A0A9J7FZ67-1", "A0A9J7JIA7-1", "A0A9J7JN73-1", "A0A9J7JR59-1", "A0A061IDH0-1", "A0A8C2M3H3-1", "A0A9J7K9A2-1", "A0A9J7G6Q5-1", "A0A9J7G6Z0-1", "A0A3L7I2I8-1", "A0A9J7JL35-1", "A0A061IFI5-1", "A0A8C2LJA1-1", "A0A8C2LLB0-1", "A0A9J7FGH3-1", "A0A9J7G9Q8-1", "A0A9J7J6R6-1", "A0A3L7I8N6-1", "A0A8C2LBB3-1", "A0A8C2LXP3-1", "A0A8C2LZI5-1" ], "evidence": [ { "id": "15801", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/15801" } ] }, { "id": "40427", "name": "", "equation": "1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GWV5-1", "G3I6R7-1", "G3H0N8-1", "A0A9J7EWD9-1", "A0A9J7FZ00-1", "A0A9J7FZ10-1", "A0A9J7FZ67-1", "A0A9J7JIA7-1", "A0A9J7JN73-1", "A0A9J7JR59-1", "A0A9J7K9A2-1", "A0A9J7G6Z0-1", "A0A9J7G6Q5-1", "A0A3L7I2I8-1", "A0A9J7JL35-1", "A0A9J7FGH3-1", "A0A8C2LZI5-1" ], "evidence": [ { "id": "40427", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40427" } ] }, { "id": "40435", "name": "", "equation": "1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + hexadecanoate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GWV5-1", "G3HKV9-1", "G3H0N8-1", "A0A3L7I8J4-1", "A0A8C2MCD7-1", "A0A9J7K9A2-1", "A0A9J7FM40-1", "A0A9J7JI58-1", "A0A9J7G7U0-1", "A0A9J7G6Q5-1", "A0A9J7G6Z0-1", "A0A3L7I2I8-1", "A0A9J7JL35-1", "A0A9J7FGH3-1", "A0A9J7G8F0-1", "A0A9J7G9Q8-1", "A0A9J7JFH6-1" ], "evidence": [ { "id": "40435", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/40435" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061IDH0", "gene_name": "Pla2g2e", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A061IDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IDH0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A061IDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IDH0" } ] } ] }, { "uniprot_ac": "A0A061IFI5", "gene_name": "LOC113833875", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A061IFI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IFI5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A061IFI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IFI5" } ] } ] }, { "uniprot_ac": "A0A3L7I2I8", "gene_name": "PLA2G6", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A3L7I2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2I8" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3L7I2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2I8" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3L7I2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2I8" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A3L7I2I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2I8" } ] } ] }, { "uniprot_ac": "A0A3L7I8J4", "gene_name": "LOC100759021", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A3L7I8J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I8J4" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A3L7I8J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I8J4" } ] } ] }, { "uniprot_ac": "A0A3L7I8N6", "gene_name": "Pla2g2f", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A3L7I8N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I8N6" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A3L7I8N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I8N6" } ] } ] }, { "uniprot_ac": "A0A8C2LBB3", "gene_name": "Prdx6", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A8C2LBB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBB3" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0A8C2LBB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBB3" } ] } ] }, { "uniprot_ac": "A0A8C2LJA1", "gene_name": "Abhd3", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A8C2LJA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA1" } ] } ] }, { "uniprot_ac": "A0A8C2LLB0", "gene_name": "Pla2g10", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8C2LLB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLB0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8C2LLB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLB0" } ] } ] }, { "uniprot_ac": "A0A8C2LXP3", "gene_name": "Pla2g2d", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8C2LXP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXP3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A8C2LXP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXP3" } ] } ] }, { "uniprot_ac": "A0A8C2LZI5", "gene_name": "LOC100764593", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A8C2LZI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZI5" } ] }, { 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] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A8C2MCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCD7" } ] } ] }, { "uniprot_ac": "A0A9J7EWD9", "gene_name": "Pla2g3", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7EWD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EWD9" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7EWD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EWD9" } ] } ] }, { "uniprot_ac": "A0A9J7FGH3", "gene_name": "Pla2g6", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "A0A9J7FGH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGH3" } ] } ] }, { "uniprot_ac": "A0A9J7FM40", "gene_name": "LOC100764608", "activity": [ { "ec_number": "3.1.2.22", "activity": "S-hexadecanoyl-L-cysteinyl-[protein] + H2O = L-cysteinyl-[protein] + hexadecanoate + H(+).", "evidence": [ { "id": "A0A9J7FM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM40" } ] }, { "ec_number": "3.1.2.22", "activity": "", "evidence": [ { "id": "A0A9J7FM40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM40" } ] } ] }, { "uniprot_ac": "A0A9J7FZ00", "gene_name": "LOC100765177", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7FZ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ00" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7FZ00", "database": "UniProtKB", "url": 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"A0A9J7FZ67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ67" } ] } ] }, { "uniprot_ac": "A0A9J7G6Q5", "gene_name": "Pla2g4e", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G6Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7G6Q5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q5" } ] } ] }, { "uniprot_ac": "A0A9J7G6Z0", "gene_name": "Pla2g4d", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" } ] } ] }, { "uniprot_ac": "A0A9J7G7U0", "gene_name": "Pnpla7", "activity": [ { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G7U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7U0" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7G7U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7U0" } ] } ] }, { "uniprot_ac": "A0A9J7G8F0", "gene_name": "Cel", "activity": [ { "ec_number": "3.1.1.-", "activity": "", "evidence": [ { "id": "A0A9J7G8F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8F0" } ] } ] }, { "uniprot_ac": "A0A9J7G9Q8", "gene_name": "Plb1", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A9J7G9Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q8" } ] } ] }, { "uniprot_ac": "A0A9J7GN25", "gene_name": "Pla2g5", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7GN25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN25" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7GN25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN25" } ] } ] }, { "uniprot_ac": "A0A9J7J6R6", "gene_name": "Pnpla3", "activity": [ { "ec_number": "2.3.1.51", "activity": "a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA.", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "2.3.1.51", "activity": "", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A9J7J6R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J6R6" } ] } ] }, { "uniprot_ac": "A0A9J7JFH6", "gene_name": "Lipc", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "A0A9J7JFH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFH6" } ] } ] }, { "uniprot_ac": "A0A9J7JI58", "gene_name": "Pnpla6", "activity": [ { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI58" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "A0A9J7JI58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI58" } ] } ] }, { "uniprot_ac": "A0A9J7JIA7", "gene_name": "LOC100763432", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JIA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIA7" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7JIA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIA7" } ] } ] }, { "uniprot_ac": "A0A9J7JL35", "gene_name": "Pla2g4b", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JL35" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7JL35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JL35" } ] } ] }, { "uniprot_ac": "A0A9J7JN73", "gene_name": "LOC100765466", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JN73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN73" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7JN73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JN73" } ] } ] }, { "uniprot_ac": "A0A9J7JR59", "gene_name": "LOC100752205", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "A0A9J7JR59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR59" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "A0A9J7JR59", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWV5" } ] } ] }, { "uniprot_ac": "G3H0N8", "gene_name": "Pnpla8", "activity": [ { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G3H0N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H0N8" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "G3H0N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H0N8" } ] } ] }, { "uniprot_ac": "G3HKV9", "gene_name": "Pla2g15", "activity": [ { "ec_number": "3.1.1.32", "activity": "a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G3HKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKV9" } ] }, { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G3HKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKV9" } ] }, { "ec_number": "3.1.1.5", "activity": "a 1-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G3HKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKV9" } ] }, { "ec_number": "3.1.1.32", "activity": "", "evidence": [ { "id": "G3HKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKV9" } ] }, { "ec_number": "3.1.1.5", "activity": "", "evidence": [ { "id": "G3HKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKV9" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "G3HKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKV9" } ] } ] }, { "uniprot_ac": "G3HU37", "gene_name": "Pla2g2a", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G3HU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HU37" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "G3HU37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HU37" } ] } ] }, { "uniprot_ac": "G3I3H3", "gene_name": "Pnpla2", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G3I3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3H3" } ] }, { "ec_number": "3.1.1.3", "activity": "a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+).", "evidence": [ { "id": "G3I3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3H3" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "G3I3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3H3" } ] }, { "ec_number": "3.1.1.3", "activity": "", "evidence": [ { "id": "G3I3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3H3" } ] } ] }, { "uniprot_ac": "G3I6R7", "gene_name": "LOC100765755", "activity": [ { "ec_number": "3.1.1.4", "activity": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "G3I6R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I6R7" } ] }, { "ec_number": "3.1.1.4", "activity": "", "evidence": [ { "id": "G3I6R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I6R7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 151, "start_aa": "His", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G6Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z0" }, { "id": "PS51210", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51210" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLA2c", "eco_id": "ECO_0000259", "start_pos": 299, "end_pos": 842, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.1.4", "ec_name": "a 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+).", "evidence": [ { "id": "3.1.1.4", "database": "Rhea", "url": 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Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007619897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007619897" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tp53bp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8", "locus": {} } ], "crossref": [ { "id": "cd17724", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17724", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17745", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17745", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20383", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20383", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767736", "url": "https://www.ncbi.nlm.nih.gov/gene/100767736", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014722", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014722", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036420", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036420", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047249", "url": 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}, { "id": "A0A9J7JS95", "url": "https://www.orthodb.org/?gene=A0A9J7JS95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15321", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15321", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15321:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15321:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007619897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007619897", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G6Z8", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEEDAGSHFSVLSRHLPNLQIHKENPVLDIVSNPEQAAAEEQGDNNSSFNEHLKENKAAADPVDSTHLGTCDSISQVIEQLPQPNRTSSVLGVTVEAASLPEEEKEEELEEENEEVGADAADAAPCSLGAEDSASSQLGFGVLELSQSQDVEEHTVPYDVNQEHMQLVTTNSGSSQLSDMDANNAVKCEEQSTEDTSMAEQPNKDIPVTVEHSKGIPVVDEQNLPPARPEDLPSSPQASAAAVETKEEVPAQELPEGALEVQMSSEPEVSSTQEDLFEQSSKTASDGCSTPSREEGGCSPVSTPATTLQLLQLSGQRPLVQDSLSTNSSDLVAPSPDAFRPTPFIVPSSPTEQGGRKDEPLDMSVMPEEGGETLQKLQDDEAVEIEKPHLPSQPAVSPQVSTPVSQSTPVFTPGSLPIPSQPEFSHDIFIPSPSLEEPSSDGKKGGDLHSSSLTVECSKTSESEPKNFTADLGLSLTGESCKLMLSSSEYSQSSKMESLASPRSEGDGENTQIEDTEPLSPVTNSKLPAESDDVLMNPAPDDQVEMNQNDDKVKEGDTENTGDHGVLAAGSKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEQHPEEGFSGSEVEEVPETPCESHREEPKEETMESIPLHLSLTETQSQALCLQKEMPKEECPEAMEVEPSVISVDSPQKLPVLDQESEHKEPEAWEEAASEDSSVEDSSVVIVDVKEPSPRVVPCEPLEGAEKCSDSHSWEDVVPEVEPCAANRVDTPEEKIVECDGDVKAETTRKDSVEEDSPQPPLPSVKDEPPRDEPPRPDQEMQQSQLQEKESPVTIDAKVADAKQLESEGASQQLSKAPARDSQSFCESSSETPFHFTLPKEGDIIPPLTGATPPHIGHLKLDRNRHSTPIGIGNYPESTIATSDVMSESMVEINDPLLGSEKGDSESAPEMDGKLYLKMKLVSPETEASEESLQFSLEKPATAERKNGSTAVAEPVASPQKTVPVFSCRQEEVWSEDPPSVPIRANLLHFPSVEEEDKEKLDGTPKLRQSEQPVRPVGLVKDAATSEDSASSVPQQRATQGSFSPQGEVMETDLLEGLSANQEKPCKVLMERPTQSNIGIQTMDHSLCAPETVSAATQTVKSVCEQGTSTVDQNSGKQDATVQTERGGVEKQAPVDDTESLHSQGEEEFEMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSSHHTSSGTSLSAMHSSGSSGRGAGPLKGKTSGTEPADFALPSSRGGPGKLSPRKGINQTGAPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRDAVVSGPLGIEDISPSMSPDDKSFTRIVPRVPDSTKRIDTSSTVLRRSDSPEIPFQAATGSSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNISSPATPTASSSSSSSSTTPTRKTTESPRASTGVPSGKRKLITSEEERSPAKRGRKSVTVKPGTVGAGEFVSPCESGDNTGEPSVLEEPRGPLPLNKTLFLGYAFLLTMATTNDKLASRSKLLDGPTGSSEEEEEFLEIPPFNKQYTECQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH", "length": 1979, "header": "tr|A0A9J7G6Z8-1|A0A9J7G6Z8_CRIGR Isoform 1 of TP53-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Tp53bp1 PE=4 SV=1 CANONICAL=A0A9J7G6Z8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G6Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8/entry#A0A9J7G6Z8-1", "sequence": { "sequence": "MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEEDAGSHFSVLSRHLPNLQIHKENPVLDIVSNPEQAAAEEQGDNNSSFNEHLKENKAAADPVDSTHLGTCDSISQVIEQLPQPNRTSSVLGVTVEAASLPEEEKEEELEEENEEVGADAADAAPCSLGAEDSASSQLGFGVLELSQSQDVEEHTVPYDVNQEHMQLVTTNSGSSQLSDMDANNAVKCEEQSTEDTSMAEQPNKDIPVTVEHSKGIPVVDEQNLPPARPEDLPSSPQASAAAVETKEEVPAQELPEGALEVQMSSEPEVSSTQEDLFEQSSKTASDGCSTPSREEGGCSPVSTPATTLQLLQLSGQRPLVQDSLSTNSSDLVAPSPDAFRPTPFIVPSSPTEQGGRKDEPLDMSVMPEEGGETLQKLQDDEAVEIEKPHLPSQPAVSPQVSTPVSQSTPVFTPGSLPIPSQPEFSHDIFIPSPSLEEPSSDGKKGGDLHSSSLTVECSKTSESEPKNFTADLGLSLTGESCKLMLSSSEYSQSSKMESLASPRSEGDGENTQIEDTEPLSPVTNSKLPAESDDVLMNPAPDDQVEMNQNDDKVKEGDTENTGDHGVLAAGSKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEQHPEEGFSGSEVEEVPETPCESHREEPKEETMESIPLHLSLTETQSQALCLQKEMPKEECPEAMEVEPSVISVDSPQKLPVLDQESEHKEPEAWEEAASEDSSVEDSSVVIVDVKEPSPRVVPCEPLEGAEKCSDSHSWEDVVPEVEPCAANRVDTPEEKIVECDGDVKAETTRKDSVEEDSPQPPLPSVKDEPPRDEPPRPDQEMQQSQLQEKESPVTIDAKVADAKQLESEGASQQLSKAPARDSQSFCESSSETPFHFTLPKEGDIIPPLTGATPPHIGHLKLDRNRHSTPIGIGNYPESTIATSDVMSESMVEINDPLLGSEKGDSESAPEMDGKLYLKMKLVSPETEASEESLQFSLEKPATAERKNGSTAVAEPVASPQKTVPVFSCRQEEVWSEDPPSVPIRANLLHFPSVEEEDKEKLDGTPKLRQSEQPVRPVGLVKDAATSEDSASSVPQQRATQGSFSPQGEVMETDLLEGLSANQEKPCKVLMERPTQSNIGIQTMDHSLCAPETVSAATQTVKSVCEQGTSTVDQNSGKQDATVQTERGGVEKQAPVDDTESLHSQGEEEFEMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSSHHTSSGTSLSAMHSSGSSGRGAGPLKGKTSGTEPADFALPSSRGGPGKLSPRKGINQTGAPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRDAVVSGPLGIEDISPSMSPDDKSFTRIVPRVPDSTKRIDTSSTVLRRSDSPEIPFQAATGSSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNISSPATPTASSSSSSSSTTPTRKTTESPRASTGVPSGKRKLITSEEERSPAKRGRKSVTVKPGTVGAGEFVSPCESGDNTGEPSVLEEPRGPLPLNKTLFLGYAFLLTMATTNDKLASRSKLLDGPTGSSEEEEEFLEIPPFNKQYTECQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH", "length": 1979, "header": "tr|A0A9J7G6Z8-1|A0A9J7G6Z8_CRIGR Isoform 1 of TP53-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Tp53bp1 PE=4 SV=1 CANONICAL=A0A9J7G6Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G745-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8/entry#A0A9J7G745-1", "sequence": { "sequence": "MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEEDAGSHFSVLSRHLPNLQIHKENPVLDIVSNPEQAAAEEQGDNNSSFNEHLKENKAAADPVDSTHLGTCDSISQVIEQLPQPNRTSSVLGVTVEAASLPEEEKEEELEEENEEVGADAADAAPCSLGAEDSASSQLGFGVLELSQSQDVEEHTVPYDVNQEHMQLVTTNSGSSQLSDMDANNAVKCEEQSTEDTSMAEQPNKDIPVTVEHSKGIPVVDEQNLPPARPEDLPSSPQASAAAVETKEEVPAQELPEGALEVQMSSEPEVSSTQEDLFEQSSKTASDGCSTPSREEGGCSPVSTPATTLQLLQLSGQRPLVQDSLSTNSSDLVAPSPDAFRPTPFIVPSSPTEQGGRKDEPLDMSVMPEEGGETLQKLQDDEAVEIEKPHLPSQPAVSPQVSTPVSQSTPVFTPGSLPIPSQPEFSHDIFIPSPSLEEPSSDGKKGGDLHSSSLTVECSKTSESEPKNFTADLGLSLTGESCKLMLSSSEYSQSSKMESLASPRSEGDGENTQIEDTEPLSPVTNSKLPAESDDVLMNPAPDDQVEMNQNDDKVKEGDTENTGDHGVLAAGSKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEQHPEEGFSGSEVEEVPETPCESHREEPKEETMESIPLHLSLTETQSQALCLQKEMPKEECPEAMEVEPSVISVDSPQKLPVLDQESEHKEPEAWEEAASEDSSVEDSSVVIVDVKEPSPRVVPCEPLEGAEKCSDSHSWEDVVPEVEPCAANRVDTPEEKIVECDGDVKAETTRKDSVEEDSPQPPLPSVKDEPPRDEPPRPDQEMQQSQLQEKESPVTIDAKVADAKQLESEGASQQLSKAPARDSQSFCESSSETPFHFTLPKEGDIIPPLTGATPPHIGHLKLDRNRHSTPIGIGNYPESTIATSDVMSESMVEINDPLLGSEKGDSESAPEMDGKLYLKMKLVSPETEASEESLQFSLEKPATAERKNGSTAVAEPVARANLLHFPSVEEEDKEKLDGTPKLRQSEQPVRPVGLVKDAATSEDSASSVPQQRATQGSFSPQGEVMETDLLEGLSANQEKPCKVLMERPTQSNIGIQTMDHSLCAPETVSAATQTVKSVCEQGTSTVDQNSGKQDATVQTERGGVEKQAPVDDTESLHSQGEEEFEMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSSHHTSSGTSLSAMHSSGSSGRGAGPLKGKTSGTEPADFALPSSRGGPGKLSPRKGINQTGAPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRDAVVSGPLGIEDISPSMSPDDKSFTRIVPRVPDSTKRIDTSSTVLRRSDSPEIPFQAATGSSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNISSPATPTASSSSSSSSTTPTRKTTESPRASTGVPSGKRKLITSEEERSPAKRGRKSVTVKPGTVGAGEFVSPCESGDNTGEPSVLEEPRGPLPLNKTLFLGYAFLLTMATTNDKLASRSKLLDGPTGSSEEEEEFLEIPPFNKQYTECQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH", "length": 1953, "header": "tr|A0A9J7G745-1|A0A9J7G745_CRIGR Computationally mapped isoform of TP53-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Tp53bp1 PE=4 SV=1 CANONICAL=A0A9J7G6Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8/entry#A0A9J7GBI8-1", "sequence": { "sequence": "MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEEDAGSHFSVLSRHLPNLQIHKENPVLDIVSNPEQAAAEEQGDNNSSFNEHLKENKAAADPVDSTHLGTCDSISQVIEQLPQPNRTSSVLGVTVEAASLPEEEKEEELEEENEEVGADAADAAPCSLGAEDSASSQLGFGVLELSQSQDVEEHTVPYDVNQEHMQLVTTNSGSSQLSDMDANNVKCEEQSTEDTSMAEQPNKDIPVTVEHSKGIPVVDEQNLPPARPEDLPSSPQASAAAVETKEEVPAQELPEGALEVQMSSEPEVSSTQEDLFEQSSKTASDGCSTPSREEGGCSPVSTPATTLQLLQLSGQRPLVQDSLSTNSSDLVAPSPDAFRPTPFIVPSSPTEQGGRKDEPLDMSVMPEEGGETLQKLQDDEAVEIEKPHLPSQPAVSPQVSTPVSQSTPVFTPGSLPIPSQPEFSHDIFIPSPSLEEPSSDGKKGGDLHSSSLTVECSKTSESEPKNFTADLGLSLTGESCKLMLSSSEYSQSSKMESLASPRSEGDGENTQIEDTEPLSPVTNSKLPAESDDVLMNPAPDDQVEMNQNDDKVKEGDTENTGDHGVLAAGSKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEQHPEEGFSGSEVEEVPETPCESHREEPKEETMESIPLHLSLTETQSQALCLQKEMPKEECPEAMEVEPSVISVDSPQKLPVLDQESEHKEPEAWEEAASEDSSVEDSSVVIVDVKEPSPRVVPCEPLEGAEKCSDSHSWEDVVPEVEPCAANRVDTPEEKIVECDGDVKAETTRKDSVEEDSPQPPLPSVKDEPPRDEPPRPDQEMQQSQLQEKESPVTIDAKVADAKQLESEGASQQLSKAPARDSQSFCESSSETPFHFTLPKEGDIIPPLTGATPPHIGHLKLDRNRHSTPIGIGNYPESTIATSDVMSESMVEINDPLLGSEKGDSESAPEMDGKLYLKMKLVSPETEASEESLQFSLEKPATAERKNGSTAVAEPVASPQKTVPVFSCRQEEVWSEDPPSVPIRANLLHFPSVEEEDKEKLDGTPKLRQSEQPVRPVGLVKDAATSEDSASSVPQQRATQGSFSPQGEVMETDLLEGLSANQEKPCKVLMERPTQSNIGIQTMDHSLCAPETVSAATQTVKSVCEQGTSTVDQNSGKQDATVQTERGGVEKQAPVDDTESLHSQGEEEFEMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSSHHTSSGTSLSAMHSSGSSGRGAGPLKGKTSGTEPADFALPSSRGGPGKLSPRKGINQTGAPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRDAVVSGPLGIEDISPSMSPDDKSFTRIVPRVPDSTKRIDTSSTVLRRSDSPEIPFQAATGSSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNISSPATPTASSSSSSSSTTPTRKTTESPRASTGVPSGKRKLITSEEERSPAKRGRKSVTVKPGTVGAGEFVSPCESGDNTGEPSVLEEPRGPLPLNKTLFLGYAFLLTMATTNDKLASRSKLLDGPTGSSEEEEEFLEIPPFNKQYTECQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH", "length": 1978, "header": "tr|A0A9J7GBI8-1|A0A9J7GBI8_CRIGR Computationally mapped isoform of TP53-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Tp53bp1 PE=4 SV=1 CANONICAL=A0A9J7G6Z8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JS95-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8/entry#A0A9J7JS95-1", "sequence": { "sequence": "MPGEQMDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEEDAGSHFSVLSRHLPNLQIHKENPVLDIVSNPEQAAAEEQGDNNSSFNEHLKENKAAADPVDSTHLGTCDSISQVIEQLPQPNRTSSVLGVTVEAASLPEEEKEEELEEENEEVGADAADAAPCSLGAEDSASSQLGFGVLELSQSQDVEEHTVPYDVNQEHMQLVTTNSGSSQLSDMDANNAVKCEEQSTEDTSMAEQPNKDIPVTVEHSKGIPVVDEQNLPPARPEDLPSSPQASAAAVETKEEVPAQELPEGALEVQMSSEPEVSSTQEDLFEQSSKTASDGCSTPSREEGGCSPVSTPATTLQLLQLSGQRPLVQDSLSTNSSDLVAPSPDAFRPTPFIVPSSPTEQGGRKDEPLDMSVMPEEGGETLQKLQDDEAVEIEKPHLPSQPAVSPQVSTPVSQSTPVFTPGSLPIPSQPEFSHDIFIPSPSLEEPSSDGKKGGDLHSSSLTVECSKTSESEPKNFTADLGLSLTGESCKLMLSSSEYSQSSKMESLASPRSEGDGENTQIEDTEPLSPVTNSKLPAESDDVLMNPAPDDQVEMNQNDDKVKEGDTENTGDHGVLAAGSKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEQHPEEGFSGSEVEEVPETPCESHREEPKEETMESIPLHLSLTETQSQALCLQKEMPKEECPEAMEVEPSVISVDSPQKLPVLDQESEHKEPEAWEEAASEDSSVEDSSVVIVDVKEPSPRVVPCEPLEGAEKCSDSHSWEDVVPEVEPCAANRVDTPEEKIVECDGDVKAETTRKDSVEEDSPQPPLPSVKDEPPRDEPPRPDQEMQQSQLQEKESPVTIDAKVADAKQLESEGASQQLSKAPARDSQSFCESSSGIGNYPESTIATSDVMSESMVEINDPLLGSEKGDSESAPEMDGKLYLKMKLVSPETEASEESLQFSLEKPATAERKNGSTAVAEPVASPQKTVPVFSCRQEEVWSEDPPSVPIRANLLHFPSVEEEDKEKLDGTPKLRQSEQPVRPVGLVKDAATSEDSASSVPQQRATQGSFSPQGEVMETDLLEGLSANQEKPCKVLMERPTQSNIGIQTMDHSLCAPETVSAATQTVKSVCEQGTSTVDQNSGKQDATVQTERGGVEKQAPVDDTESLHSQGEEEFEMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSSHHTSSGTSLSAMHSSGSSGRGAGPLKGKTSGTEPADFALPSSRGGPGKLSPRKGINQTGAPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRDAVVSGPLGIEDISPSMSPDDKSFTRIVPRVPDSTKRIDTSSTVLRRSDSPEIPFQAATGSSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNISSPATPTASSSSSSSSTTPTRKTTESPRASTGVPSGKRKLITSEEERSPAKRGRKSVTVKPGTVGAGEFVSPCESGDNTGEPSVLEEPRGPLPLNKTLFLGYAFLLTMATTNDKLASRSKLLDGPTGSSEEEEEFLEIPPFNKQYTECQLRAGAGYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH", "length": 1939, "header": "tr|A0A9J7JS95-1|A0A9J7JS95_CRIGR Computationally mapped isoform of TP53-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Tp53bp1 PE=4 SV=1 CANONICAL=A0A9J7G6Z8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1642, "start_aa": "Thr", "end_pos": 1642, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1642", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 339, "start_aa": "Thr", "end_pos": 339, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr339", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767736", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767736", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8" } ], "pmid": "" }, { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8" } ], "pmid": "" }, { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Z8" } ], "pmid": "" }, { 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Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027274585.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274585" } ] }, { "annotation": "Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response. Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota. Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response. Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G708", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G708#function" }, { "database": "UniProtKB", "id": "ARBA00057507", "url": "https://www.uniprot.org/uniprotkb/ARBA00057507#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G708", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G708" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tlr5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G708", "locus": {} } ], "crossref": [ { "id": "A0A9J7G708", "url": 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G708", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G708" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G708", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G708" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772103", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772103", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G708", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G708" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278752" } ] }, { "annotation": "Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. 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"MDIDAEREKITQEIQELERILYPGSSSVHLEVSESSLSSDSEADLLPDEDLEATGTPIVEEERWSEASNDEEDPKDKALPEDPETCLQLNMVYQEVIQEKLAEVSQLLAQNQEQQEEILYDLSGTKCSKVKDGKSLPSYMYIGHFMKPYFKDKVTGVGPPANEDTREKAAQGIKAFEQLLVTKWKHWEKALLRKSVVSDRLQRLLQPKMLKLEYLHEKQTRVSSDLERQALEKQIKEAEKEIQDINQLPEEALLGNRLDNHDWEKISNINFEGGRSAEEIQKFWQSSEHPSINKQEWSTEEVERLKAIAATHSHLEWHLVAEELGTSRSAFQCLQKFQQYNKALKRKEWTEEEDHMLTQLVQEMRVGNHIPYRKIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWTPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWNAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKIMARKQQHLQRRRGRRPNRSSQWSSSSSSDSEGYGSSNSSSSSSSSSEDSELELEEPLENGRALVPQQYRVPDIDLWVPTRLITSQSQREGAGCYPAHRAASCTLDTTQSHHKEGPTTVSTPQISQVLPQSALPGLTKSCYICTRSCGSQPYRVSFDMQHVVKVPLEKMLKLIRARPATQNHTLVKERLRQPSLPNSHSESDPGDNVAVPHLRRLWHGTFQNKLRRKRQALHRRLLKHRLLLAVIPWVGDINLSCTQAPRRPAIVQTQADSIRTQLERAHLTSTPVFTLLIQVSQLLQIDAVGCMEVVRERKAQPPAVLQPSTQNPQPHLLQAFSSAKNSTGCLLPSMPGQQTTKRDSHKGRPRLGTCGTEATSFQVPVAAPGGLRPKPKTVSELLREKRLRESRAKKATQALTAINSQLLISSPVILQPPLLPAPQGSPVAGPATSSVELSVPVAPVMVSSSPSGSWQVTGMSATDKQPPIQQTIPLNASHKGTQIAAPAAFRSLALAPRQVPTGCPLSTLGQSQASVTSQKQGLSKVLPLLPASPSPTQLPVQPLSLPPVLGSQASGQPQAAKASLPINWVLTTQKLLSVPVPAVSLPQSVMTPDTIGPPAKQLPSPATTPACLGQLPASTDTEPKGPQGQEIPTISGPEKKALDLSLLSQESETATLTWLKGCQGACVPPLGSRMPYQPPSLCSLRALSSLLLHKKDLEQKASSLVTSQAAGSQSEPKAEALQTSLGLVQRQLQDNPAYLLLKTRFLALFSLPALLATLPPNSVPTTLSPAVAVGSESDSEDLLGDLELKDRARQLDCLACRIQASPAATDPEQRAPGPGEDLDASDDLDVLRTRHARHSRKRRLL", 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"length": 1352, "header": "tr|A0A9J7G732-1|A0A9J7G7L0_CRIGR Computationally mapped isoform of snRNA-activating protein complex subunit 4 OS=Cricetulus griseus OX=10029 GN=Snapc4 PE=4 SV=1 CANONICAL=A0A9J7G7L0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L0/entry#A0A9J7G7L0-1", "sequence": { "sequence": "MDIDAEREKITQEIQELERILYPGSSSVHLEVSESSLSSDSEADLLPDEDLEATGTPIVEEERWSEASNDEEDPKDKALPEDPETCLQLNMVYQEVIQEKLAEVSQLLAQNQEQQEEILYDLSGTKCSKVKDGKSLPSYMYIGHFMKPYFKDKVTGVGPPANEDTREKAAQGIKAFEQLLVTKWKHWEKALLRKSVVSDRLQRLLQPKMLKLEYLHEKQTRVSSDLERQALEKQIKEAEKEIQDINQLPEEALLGNRLDNHDWEKISNINFEGGRSAEEIQKFWQSSEHPSINKQEWSTEEVERLKAIAATHSHLEWHLVAEELGTSRSAFQCLQKFQQYNKALKRKEWTEEEDHMLTQLVQEMRVGNHIPYRKIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWTPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWNAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKIMARKQQHLQRRRGRRPNRSSQWSSSSSSDSEGYGSSNSSSSSSSSSEDSELELEEPLENGRALVPQQYRVPDIDLWVPTRLITSQSQREGAGCYPAHRAASCTLDTTQSHHKEGPTTVSTPQISQVLPQSALPGLTKSCYICTRSCGSQPYRVSFDMQHVVKVPLEKMLKLIRARPATQNHTLVKERLRQPSLPNSHSESDPGDNVAVPHLRRLWHGTFQNKLRRKRQALHRRLLKHRLLLAVIPWVGDINLSCTQAPRRPAIVQTQADSIRTQLERAHLTSTPVFTLLIQVSQLLQIDAVGCMEVVRERKAQPPAVLQPSTQNPQPHLLQAFSSAKNSTGCLLPSMPGQQTTKRDSHKGRPRLGTCGTEATSFQVPVAAPGGLRPKPKTVSELLREKRLRESRAKKATQALTAINSQLLISSPVILQPPLLPAPQGSPVAGPATSSVELSVPVAPVMVSSSPSGSWQVTGMSATDKQPPIQQTIPLNASHKGTQIAAPAAFRSLALAPRQVPTGCPLSTLGQSQASVTSQKQGLSKVLPLLPASPSPTQLPVQPLSLPPVLGSQASGQPQAAKASLPINWVLTTQKLLSVPVPAVSLPQSVMTPDTIGPPAKQLPSPATTPACLGQLPASTDTEPKGPQGQEIPTISGPEKKALDLSLLSQESETATLTWLKGCQGACVPPLGSRMPYQPPSLCSLRALSSLLLHKKDLEQKASSLVTSQAAGSQSEPKAEALQTSLGLVQRQLQDNPAYLLLKTRFLALFSLPALLATLPPNSVPTTLSPAVAVGSESDSEDLLGDLELKDRARQLDCLACRIQASPAATDPEQRAPGPGEDLDASDDLDVLRTRHARHSRKRRLL", "length": 1355, "header": "tr|A0A9J7G7L0-1|A0A9J7G7L0_CRIGR Isoform 1 of snRNA-activating protein complex subunit 4 OS=Cricetulus griseus OX=10029 GN=Snapc4 PE=4 SV=1 CANONICAL=A0A9J7G7L0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K8M0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L0/entry#A0A9J7K8M0-1", "sequence": { "sequence": "MDIDAEREKITQEIQELERILYPGSSSVHLEVSESSLSSDSEADLLPDEDLEATGTPIVEEERWSEASNDEEDPKDKALPEDPETCLQLNMVYQEVIQEKLAEVSQLLAQNQEQQEEILYDLSGTKCSKVKDGKSLPSYMYIGHFMKPYFKDKVTGVGPPANEDTREKAAQGIKAFEQLLVTKWKHWEKALLRKSVVSDRLQRLLQPKMLKLEYLHEKQTRVSSDLERQALEKQIKEAEKEIQDINQLPEEALLGNRLDNHDWEKISNINFEGGRSAEEIQKFWQSSEHPSINKQEWSTEEVERLKAIAATHSHLEWHLVAEELGTSRSAFQCLQKFQQYNKALKRKEWTEEEDHMLTQLVQEMRVGNHIPYRKIVYFMEGRDSMQLIYRWTKSLDPSLKRGFWTPEEDAKLLQAVAKYGAQDWFKIREEVPGRSDAQCRDRYIRRLHFSLKKGRWNAKEEQQLIQLIEKYGVGHWARIASELPHRSGSQCLSKWKIMARKQQHLQRRRGRRPNRSSQWSSSSSSDSEGYGSSNSSSSSSSSSEDSELELEEPLENGRALVPQQYRVPDIDLWVPTRLITSQSQREGAGCYPAHRAASCTLDTTQSHHKEGPTTVSTPQISQHVVKVPLEKMLKLIRARPATQNHTLVKERLRQPSLPNSHSESDPGDNVAVPHLRRLWHGTFQNKLRRKRQALHRRLLKHRLLLAVIPWVGDINLSCTQAPRRPAIVQTQADSIRTQLERAHLTSTPVFTLLIQVSQLLQIDAVGCMEVVRERKAQPPAVLQPSTQNPQPHLLQAFSSAKNSTGCLLPSMPGQQTTKRDSHKGRPRLGTCGTEATSFQVPVAAPGGLRPKPKTVSELLREKRLRESRAKKATQALTAINSQLLISSPVILQPPLLPAPQGSPVAGPATSSVELSVPVAPVMVSSSPSGSWQVTGMSATDKQPPIQQTIPLNASHKGTQIAAPAAFRSLALAPRQVPTGCPLSTLGQSQASVTSQKQGLSKVLPLLPASPSPTQLPVQPLSLPPVLGSQASGQPQAAKASLPINWVLTTQKLLSVPVPAVSLPQSVMTPDTIGPPAKQLPSPATTPACLGQLPASTDTEPKGPQGQEIPTISGPEKKALDLSLLSQESETATLTWLKGCQGACVPPLGSRMPYQPPSLCSLRALSSLLLHKKDLEQKASSLVTSQAAGSQSEPKAEALQTSLGLVQRQLQDNPAYLLLKTRFLALFSLPALLATLPPNSVPTTLSPAVAVGSESDSEDLLGDLELKDRARQLDCLACRIQASPAATDPEQRAPGPGEDLDASDDLDVLRTRHARHSRKRRLL", "length": 1322, "header": "tr|A0A9J7K8M0-1|A0A9J7K8M0_CRIGR Computationally mapped isoform of snRNA-activating protein complex subunit 4 OS=Cricetulus griseus OX=10029 GN=Snapc4 PE=4 SV=1 CANONICAL=A0A9J7G7L0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G732", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G732" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G732", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G732" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761303", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761303", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7L0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L0" } ], "pmid": "" }, { "name": "RNA polymerase III type 3 promoter sequence-specific DNA binding", "id": "GO:0001006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001006", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7L0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "snRNA-activating protein complex", "id": "GO:0019185", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019185", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7L0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "snRNA transcription by RNA polymerase II", "id": "GO:0042795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042795", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7L0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L0" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase III", "id": "GO:0042796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042796", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7L0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 677, "end_pos": 679, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 835, "end_pos": 837, "annotation": "n_glycosylation_sequon" }, { "start_pos": 985, "end_pos": 987, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L0" }, { "id": "PS51294", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51294" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH myb-type", "eco_id": "ECO_0000259", "start_pos": 289, "end_pos": 345, "start_aa": "His", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L0" }, { "id": "PS50090", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb-like", "eco_id": "ECO_0000259", "start_pos": 289, "end_pos": 341, "start_aa": "His", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L0" }, { "id": "PS51293", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SANT", "eco_id": "ECO_0000259", "start_pos": 404, "end_pos": 445, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 514, "end_pos": 516 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 677, "end_pos": 679 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 835, "end_pos": 837 }, { "start_pos": 985, "end_pos": 987 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G738-1", "uniprot_ac": "A0A9J7G738", "uniprot_id": "A0A9J7G738_CRIGR", "mass": { "chemical_mass": 53418.0, "monoisotopic_mass": 53418.0 }, "refseq": { "ac": "XP_027275440", "name": "melanoma inhibitory activity protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275440" }, "gene_names": [ { "name": "LOC100767997", "type": "recommended", "evidence": [ { "id": "A0A9J7G738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G738" } ] }, { "name": "LOC100767997", "type": "synonym", "evidence": [ { "id": "XP_027275440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275440" } ] } ], "protein_names": [ { "name": "Melanoma inhibitory activity protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7G738", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G738/entry#names_and_taxonomy" } ] }, { "name": "melanoma inhibitory activity protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027275440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275440" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756/entry#names_and_taxonomy" } ] }, { "name": "RNA pseudouridylate synthase domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_003508365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508365" }, { "id": "A0A9J7G756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614523.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508365" } ] }, { "annotation": "Pseudouridine synthase that catalyzes pseudouridylation of mRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G756", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756#function" }, { "database": "UniProtKB", "id": "ARBA00057241", "url": "https://www.uniprot.org/uniprotkb/ARBA00057241#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G756", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rpusd2", "url": 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"MWRGVHGCLGILVQWRVAPWSHSFARTWSGCRETMAEALSTQAKAAGLKALVQHNGDSGSDQSRERLLEGLDLAAVGEQVPGSREQGQGGEEQVSGNAGQTPAPVADSGKRKKRRGATGERVVPPPKKRRTGVSFGDEHFAETTYYFEGGLRKVRPYYFDFQTYCKGRWVGRSLLHVFSTEFRSQPLEYYEAAVRAGRLHLNEEPVQDLSIVLKDNDFLRNTVHRHEPPVTAEPIRLLAENEDVVVIDKPSSIPVHPCGRFRHNTVIFILGKEHHLKELHPLHRLDRLTSGVLMFAKTAAFSEKIHEQVRDRQLEKEYVCRVEGEFPDKEVICKEPILVVSYKVGVCRVDPRGKPCETVFQRLSYNGHSSVVQCRPLTGRTHQIRVHLQFLGHPILNDPIYNSTAWGPSRGQGGHIPKTDEELLRDLVAEHQAKESLNVLDLCEGDLAPGLMDSTAPSSKLAKNSLEELASVAQKIERIAEAPSQDLDTPEKAAKAEVMNQETDPLCAECRLSRQDPLPQDLVMFLHALRYKGPDFEYVSPMPAWAQDDWQED", "length": 553, "header": "tr|A0A9J7G756-1|A0A9J7G756_CRIGR Isoform 1 of Pseudouridylate synthase RPUSD2 OS=Cricetulus griseus OX=10029 GN=Rpusd2 PE=3 SV=1 CANONICAL=A0A9J7G756-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G756-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756/entry#A0A9J7G756-1", "sequence": { "sequence": 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G756", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G756", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752640", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752640", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZYZ4-1", "protein_name": "Pseudouridine synthase", "gene_name": "RPUSD2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEPGPGLQAEVGKVDEEKETAAPAPKKRRLAAGERYVPPPRKLRSGVSFSAAHFAETSYYFEGGLRKVRPYYYDFRTYCKGRWVGRSLLHVFSTEFRAQPLSYYRAAARAGRLRLNEEPVQDLNVVLKNNDFLRNTVHRHEPPVTAQPIQILVENDEVVVVDKPSSLPVHPCGRFRHNTVIFILGKEHNLKELHTIHRLDRMTSGVLMFAKTVEVSKRIDEQVRERQLEKEYVCRVVGEFPEHEVVCEEPILVVSYKVGVCRVDPKGKCCKTIFQRLSYNGKSSVVKCLPHTGRTHQIRVHLQYLGYPIVNDPIYNMEAWGPEKGKGGKIGKTDEELLKALVEEHRSKQSLDILGISEEDLNSNAENNDSGNSSECTESVQADHISENSCLAEDIKGSEIKEVATYPLNFNTNLETLEKNTELGSCENEGRQMGEESTEERDPLCVECKITRRDPSPKELVMYLHALRYKGAEFDYCSKMPEWAMEDWEE", "length": 491 }, "evidence": [ { "id": "A0A9J7G756", "url": "https://omabrowser.org/oma/group/A0A9J7G756/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ACD4-1", "protein_name": "Pseudouridylate synthase RPUSD2", "gene_name": "Rpusd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTPSYRDPEAACHAVMWRSVPGCLRYIVQWQVALWSHSFVRTWGSCGKAMTEALSAQAEAADGLKALIEQNGDTGSDTRGEPHLELLEPATVGKQVPESGEQAQGGEEQLPGNGEQAPTPVADSGKRKKRRGATGERVVPPPKKRRTGVSFSDEHFAETTYYFEGGLRKVRPYYFDFQTYCKGRWVGRSLLHVFSTEFRSQPLAYYEAAVRAGRLHLNEEPVQDLNIVLKDNDFLRNTVHRHEPPVTAEPIRLLAENDDVVVIDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSEKIHEQVRDRQLEKEYVCRVAGEFPDKEVICKEPILVVSYKVGVCRVDPQGKPCETVFQRLSYNGRSSVVQCRPLTGRTHQIRVHLQFLGHPILNDPIYNSTAWGPSRGQGGHIPKTDEELLRDLVAEHQAKESLSMLDLCEGDLAPGLIDSTAPSSELGKDSLEGLATAAQKIDGMVDEASQHPDTPGKAAKADVSQQTDPLCAECRVLRQDPLPQDLVMFLHALRYKGPDFEYVSPIPAWAQADWQED", "length": 568 }, "evidence": [ { "id": "A0A9J7G756", "url": "https://omabrowser.org/oma/group/A0A9J7G756/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12069-1", "protein_name": "tRNA pseudouridine(32) synthase, mitochondrial", "gene_name": "PUS9", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQRNNRLRNLFTVPVIMARQLKRNALSAGLAFAGNATSNEFDEHLQNEVEREREIQKKKKIKRTQSKKSPDLINKSTFQSRTIGSKKEKHRQLDPEYEIVIDGPLRKIKPYHFTYRTFCKERWRDKKLVDVFISEFRDRESEYYKRTIENGDVHINDETADLSTVIRNGDLITHQVHRHEPPVTSRPIKVIFEDDNIMVIDKPSGIPVHPTGRYRFNTITKMLQNNLGFVVNPCNRLDRLTSGLMFLAKTPKGADNIGDQLKAREVTKEYVAKVVGEFPETEVIVEKPLKLIEPRLALNAVCQMDEKGAKHAKTVFNRISYDGKTSIVKCKPLTGRSHQIRVHLQYLGHPIANDPIYSNDEVWGNNLGKGGQADFDIVITKLDEIGKRKPAKSWFHSNGGYGEVLRQEKCSICESDLYTDPGPNDLDLWLHAYLYESTETEEGTEKKKWCYKTEYPEWALRR", "length": 462 }, "evidence": [ { "id": "A0A9J7G756", "url": "https://omabrowser.org/oma/group/A0A9J7G756/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q149F1-1", "protein_name": "Pseudouridylate synthase RPUSD2", "gene_name": "Rpusd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRGVPGCLRDIVQWQVALWSHSFVRTWGSCGKAMTEALSAQAEAAGGLKALVQPNGDAGSNTSGEPLLERLEPAAVGKQVPESGDQAQGGEGQLPSNGEQTPAPVADSGKRKKRRGATGERVVPPPKKRRTGVSFSDEHFAETTYYFEGGLRKVRPYYFDFQTYCKGRWVGRSLLHVFSTEFRSQPLSYYEAAVRAGRLHLNEEPVQDLSIVLKDNDFLRNTVHRHEPPVTAEPIHLLAENNDVVVIDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSEKIHEQVRDRQLEKEYVCRVAGEFPDKEVICKEPILVVSYKVGVCRVDPRGKPCETVFQRLSYNGRSSVVQCRPLTGRTHQIRVHLQFLGHPILNDPIYNSTAWGPSRGQGGHIPKTDEELLRDLVAEHQAKESLSMLDLCESDLTPGLIDSTAPSSELAKDSLEGLATAAQKIDGIAEAAPQHLDTPEKAAKADVTQETDPLCAECRVLRQDPLPQDLVMFLHALRYKGPDFEYVSPIPAWARDDWQED", "length": 553 }, "evidence": [ { "id": "A0A9J7G756", "url": "https://omabrowser.org/oma/group/A0A9J7G756/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZ73-1", "protein_name": "Pseudouridylate synthase RPUSD2", "gene_name": "RPUSD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLDRRGWLRVLGHWRYDLRRPSFTRTWSGDKGPMAETVSTQVGTEGGLRASHQQNGDAGGDAKVELSPGPPKPAGREVEPAPVGGEHPSAAAPGPGKHKKRRGATRERVVPPPKKRRTGVSFGDEHFAETSYYFEGGLRKVRPYYFDFRTYCKGRWVGHSLLHVFSTEFRAQPLAYYEAAVRAGRLQLNEKPVQDLNIVLKDNDFLRNTVHRHEPPVTAEPIRLLAENEDVVVVDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSERIHEQVRDRQLEKEYVCRVEGEFPTEEVTCKEPILVVSYKVGVCRVDPRGKPCETVFQRLSYNGQSSVVRCRPLTGRTHQIRVHLQFLGHPILNDPIYNSVAWGPSRGRGGYIPKTNEELLRDLVAEHQAKQSLDVLDLCEGDLSPGLTDSTAPSSELGKDDLEELAAAAQKMEEVAEAAPQELDTIALASEKAVETDVMNQETDPLCAECRLVRQDPLPQDLVMFLHALRYKGPGFEYFSPMPAWAQDDWQKD", "length": 545 }, "evidence": [ { "id": "A0A9J7G756", "url": "https://omabrowser.org/oma/group/A0A9J7G756/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VKU8-1", "protein_name": "Pseudouridylate synthase RPUSD2", "gene_name": "RluA-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MESSKLLRNAQTQHGDASSVDVENIFLHRHMLYTNPTSDGNLHDREDSPECVWCPDDKDGSPAESKDPPISISEEKSETQSKEVLSEKRKASSTDDEGHVKKVKLEANSLKTKRPGFSDERYDETSYYFENGLRKVYPYFFTFTTFAKGRWVDEKILDVFVREFRAAPPEEYERSLEAGKLTVNSEKVPKDYKIKHNDLLANVVHRHEVPVTSQPIKIVYMDKDIVVVNKPASIPVHPCGRYRHNTVVFILAKEHNLKNLRTIHRLDRLTSGLLLFGRTAEKARELELQIRTRQVQKEYVCRVEGRFPDGIVECNEKIDVVSYKIGVCKVSPKGKDCKTTFKRIGEVGSDSIVLCKPLTGRMHQIRVHLQFLGYPISNDPLYNHEVFGPLKGRGGDIGGITEEQLISNLISIHNAENWLGLEGDQIVSGEIKDVAASTSVVEAPSVVQAPINSETEKPVISKNLEPSNDATAQIATQTCYEEPDRSFDSKKTTSDPQCSECKINYRDPGTKDLIMYLHAWKYKGVGWEYETELPEWACNSNIDYDKV", "length": 547 }, "evidence": [ { "id": "A0A9J7G756", "url": "https://omabrowser.org/oma/group/A0A9J7G756/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "enzyme-directed rRNA pseudouridine synthesis", "id": "GO:0000455", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000455", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G756", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756" } ], "pmid": "" }, { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G756", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G756", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756" } ], "pmid": "" }, { "name": "pseudouridine synthase activity", "id": "GO:0009982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009982", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G756", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G756" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 402, "end_pos": 404, "annotation": 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276555" } ] } ], "protein_names": [ { "name": "Zinc finger protein 473 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7G9L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 473 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027276555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276555" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276555" } ] }, { "annotation": "Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G767", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G767#function" }, { "database": "UniProtKB", "id": "ARBA00054787", "url": "https://www.uniprot.org/uniprotkb/ARBA00054787#function" }, { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8#function" }, { "database": "UniProtKB", "id": "A0A9J7JUQ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUQ1#function" }, { "database": "UniProtKB", "id": "A0A9J7JZA8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZA8#function" }, { "database": "UniProtKB", "id": "A0A9J7K6Q1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6Q1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": 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Classification" ] }, { "id": "IPR050826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769900", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769900", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9L8", "url": "https://www.orthodb.org/?gene=A0A9J7G9L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G767", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G767", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G767-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G767-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUQ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZA8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6Q1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGKEEELKRGHWKEATVAECASFQEFVTLKDTAMDLTLEDWEELELELDKRDLFWDLTLSNCQDFFLLNPPKPGLNSQPDVREELEATIKGGLEATGTEVTETKNSPLQQGFLEEGLSQIMETLSEEELNFEAYIGESWLDSLLGDPESLARSDITNTESPTDCKSHEFESSLSPGPLFSTGEDAGMSDILPKNLTPVIVKESRSDFSYYLEQSQKDSIQGEEKLYKCSECGKSFNQSYHLLQHWIIHVRDNTPSRQDKERELSTGAFLLMRPVTQTSYKPCVCQECGKRFSQNMYLQWHQKVHTGESLCKTQCDNLEKPSKSHSGEPKKLLPSKGSNSAKWCKIQSSDQAKPPDSNSSDQKKLHKSQCDGSPSILHPQPTEHQKTPANTKFYVCKKCGKTFSQAFHLAGHQKVHTEKLYECPTCHQVFHVRKHFVQHRKTHFVKTVFECQECKKIFNQRSSLIEHQAVHTGEKPYKCTECGKAFNHSSTLKIHQRAHSGEKPYKCSECGRAFCRSTHLHEHQQIHSGHRPYQCPECVRSFSRPSHLIRHQLSHTTDKPFGCAKCKNTFSHKEQLVQHHKVHTIESLYECKQCGEHFICSSTLHCHMSVHTREDISQKVSGQNKCGKAFNHNRYVGQHENSHTKVTSSECNPCVETYNQSLQLPCHQSIIQVGIKPDECTEPDTSKRNSSVSKHQPSGSEQPFKCNSCNRTFSQDAQLFKHQLIHTGEKPFKCNECDRAFKQSNYLIQHQRIHTVKQHFECSECGKTFRQSSCLSKHQKIHTGEKPFKCGDCGKAFILGAQLTRHQRIHTGEKPYVCQECGKAFSQSSCLTLHRRVHTGEKPYKCSRCGKAFSQRANQKKHERIHSGEKPYTCDVCGRAFGLSAHLSQHQRVHTQEKPHCQDCHRAFHSCSALSKHQQLHSCKVTSSTAQSHLVTAESRTCEDIHRKSVIETNTLQTSPLNKF", "length": 964, "header": "tr|A0A9J7G9L8-1|A0A9J7G9L8_CRIGR Isoform 1 of Zinc finger protein 473 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf473 PE=3 SV=1 CANONICAL=A0A9J7G9L8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G767-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8/entry#A0A9J7G767-1", "sequence": { "sequence": "MEGKEEELKRGHWKEATVAECASFQEFVTLKDTAMDLTLEDWEELELELDKRDLFWDLTLSNCQDFFLLNPPKPGLNSQPDVREELEATIKGGLEATGTEVTETKNSPLQQGFLEEGLSQIMETLSEEELNFEAYIGEDAGMSDILPKNLTPVIVKESRSDFSYYLEQSQKDSIQGEEKLYKCSECGKSFNQSYHLLQHWIIHVRDNTPSRQDKERELSTGAFLLMRPVTQTSYKPCVCQECGKRFSQNMYLQWHQKVHTGESLCKTQCDNLEKPSKSHSGEPKKLLPSKGSNSAKWCKIQSSDQAKPPDSNSSDQKKLHKSQCDGSPSILHPQPTEHQKTPANTKFYVCKKCGKTFSQAFHLAGHQKVHTEKLYECPTCHQVFHVRKHFVQHRKTHFVKTVFECQECKKIFNQRSSLIEHQAVHTGEKPYKCTECGKAFNHSSTLKIHQRAHSGEKPYKCSECGRAFCRSTHLHEHQQIHSGHRPYQCPECVRSFSRPSHLIRHQLSHTTDKPFGCAKCKNTFSHKEQLVQHHKVHTIESLYECKQCGEHFICSSTLHCHMSVHTREDISQKVSGQNKCGKAFNHNRYVGQHENSHTKVTSSECNPCVETYNQSLQLPCHQSIIQVGIKPDECTEPDTSKRNSSVSKHQPSGSEQPFKCNSCNRTFSQDAQLFKHQLIHTGEKPFKCNECDRAFKQSNYLIQHQRIHTVKQHFECSECGKTFRQSSCLSKHQKIHTGEKPFKCGDCGKAFILGAQLTRHQRIHTGEKPYVCQECGKAFSQSSCLTLHRRVHTGEKPYKCSRCGKAFSQRANQKKHERIHSGEKPYTCDVCGRAFGLSAHLSQHQRVHTQEKPHCQDCHRAFHSCSALSKHQQLHSCKVTSSTAQSHLVTAESRTCEDIHRKSVIETNTLQTSPLNKF", "length": 918, "header": "tr|A0A9J7G767-1|A0A9J7G9L8_CRIGR Computationally mapped isoform of Zinc finger protein 473 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf473 PE=3 SV=1 CANONICAL=A0A9J7G9L8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8/entry#A0A9J7G9L8-1", "sequence": { "sequence": "MEGKEEELKRGHWKEATVAECASFQEFVTLKDTAMDLTLEDWEELELELDKRDLFWDLTLSNCQDFFLLNPPKPGLNSQPDVREELEATIKGGLEATGTEVTETKNSPLQQGFLEEGLSQIMETLSEEELNFEAYIGESWLDSLLGDPESLARSDITNTESPTDCKSHEFESSLSPGPLFSTGEDAGMSDILPKNLTPVIVKESRSDFSYYLEQSQKDSIQGEEKLYKCSECGKSFNQSYHLLQHWIIHVRDNTPSRQDKERELSTGAFLLMRPVTQTSYKPCVCQECGKRFSQNMYLQWHQKVHTGESLCKTQCDNLEKPSKSHSGEPKKLLPSKGSNSAKWCKIQSSDQAKPPDSNSSDQKKLHKSQCDGSPSILHPQPTEHQKTPANTKFYVCKKCGKTFSQAFHLAGHQKVHTEKLYECPTCHQVFHVRKHFVQHRKTHFVKTVFECQECKKIFNQRSSLIEHQAVHTGEKPYKCTECGKAFNHSSTLKIHQRAHSGEKPYKCSECGRAFCRSTHLHEHQQIHSGHRPYQCPECVRSFSRPSHLIRHQLSHTTDKPFGCAKCKNTFSHKEQLVQHHKVHTIESLYECKQCGEHFICSSTLHCHMSVHTREDISQKVSGQNKCGKAFNHNRYVGQHENSHTKVTSSECNPCVETYNQSLQLPCHQSIIQVGIKPDECTEPDTSKRNSSVSKHQPSGSEQPFKCNSCNRTFSQDAQLFKHQLIHTGEKPFKCNECDRAFKQSNYLIQHQRIHTVKQHFECSECGKTFRQSSCLSKHQKIHTGEKPFKCGDCGKAFILGAQLTRHQRIHTGEKPYVCQECGKAFSQSSCLTLHRRVHTGEKPYKCSRCGKAFSQRANQKKHERIHSGEKPYTCDVCGRAFGLSAHLSQHQRVHTQEKPHCQDCHRAFHSCSALSKHQQLHSCKVTSSTAQSHLVTAESRTCEDIHRKSVIETNTLQTSPLNKF", "length": 964, "header": "tr|A0A9J7G9L8-1|A0A9J7G9L8_CRIGR Isoform 1 of Zinc finger protein 473 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf473 PE=3 SV=1 CANONICAL=A0A9J7G9L8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JUQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8/entry#A0A9J7JUQ1-1", "sequence": { "sequence": "MEGKEEELKRGHWKEATVAEEFVTLKDTAMDLTLEDWEELELELDKRDLFWDLTLSNCQDFFLLNPPKPGLNSQPDVREELEATIKGGLEATGTEVTETKNSPLQQGFLEEGLSQIMETLSEEELNFEAYIGESWLDSLLGDPESLARSDITNTESPTDCKSHEFESSLSPGPLFSTGEDAGMSDILPKNLTPVIVKESRSDFSYYLEQSQKDSIQGEEKLYKCSECGKSFNQSYHLLQHWIIHVRDNTPSRQDKERELSTGAFLLMRPVTQTSYKPCVCQECGKRFSQNMYLQWHQKVHTGESLCKTQCDNLEKPSKSHSGEPKKLLPSKGSNSAKWCKIQSSDQAKPPDSNSSDQKKLHKSQCDGSPSILHPQPTEHQKTPANTKFYVCKKCGKTFSQAFHLAGHQKVHTEKLYECPTCHQVFHVRKHFVQHRKTHFVKTVFECQECKKIFNQRSSLIEHQAVHTGEKPYKCTECGKAFNHSSTLKIHQRAHSGEKPYKCSECGRAFCRSTHLHEHQQIHSGHRPYQCPECVRSFSRPSHLIRHQLSHTTDKPFGCAKCKNTFSHKEQLVQHHKVHTIESLYECKQCGEHFICSSTLHCHMSVHTREDISQKVSGQNKCGKAFNHNRYVGQHENSHTKVTSSECNPCVETYNQSLQLPCHQSIIQVGIKPDECTEPDTSKRNSSVSKHQPSGSEQPFKCNSCNRTFSQDAQLFKHQLIHTGEKPFKCNECDRAFKQSNYLIQHQRIHTVKQHFECSECGKTFRQSSCLSKHQKIHTGEKPFKCGDCGKAFILGAQLTRHQRIHTGEKPYVCQECGKAFSQSSCLTLHRRVHTGEKPYKCSRCGKAFSQRANQKKHERIHSGEKPYTCDVCGRAFGLSAHLSQHQRVHTQEKPHCQDCHRAFHSCSALSKHQQLHSCKVTSSTAQSHLVTAESRTCEDIHRKSVIETNTLQTSPLNKF", "length": 959, "header": "tr|A0A9J7JUQ1-1|A0A9J7JUQ1_CRIGR Computationally mapped isoform of Zinc finger protein 473 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf473 PE=3 SV=1 CANONICAL=A0A9J7G9L8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8/entry#A0A9J7JZA8-1", "sequence": { "sequence": "METLSEEELNFEAYIGEDAGMSDILPKNLTPVIVKESRSDFSYYLEQSQKDSIQGEEKLYKCSECGKSFNQSYHLLQHWIIHVRDNTPSRQDKERELSTGAFLLMRPVTQTSYKPCVCQECGKRFSQNMYLQWHQKVHTGESLCKTQCDNLEKPSKSHSGEPKKLLPSKGSNSAKWCKIQSSDQAKPPDSNSSDQKKLHKSQCDGSPSILHPQPTEHQKTPANTKFYVCKKCGKTFSQAFHLAGHQKVHTEKLYECPTCHQVFHVRKHFVQHRKTHFVKTVFECQECKKIFNQRSSLIEHQAVHTGEKPYKCTECGKAFNHSSTLKIHQRAHSGEKPYKCSECGRAFCRSTHLHEHQQIHSGHRPYQCPECVRSFSRPSHLIRHQLSHTTDKPFGCAKCKNTFSHKEQLVQHHKVHTIESLYECKQCGEHFICSSTLHCHMSVHTREDISQKVSGQNKCGKAFNHNRYVGQHENSHTKVTSSECNPCVETYNQSLQLPCHQSIIQVGIKPDECTEPDTSKRNSSVSKHQPSGSEQPFKCNSCNRTFSQDAQLFKHQLIHTGEKPFKCNECDRAFKQSNYLIQHQRIHTVKQHFECSECGKTFRQSSCLSKHQKIHTGEKPFKCGDCGKAFILGAQLTRHQRIHTGEKPYVCQECGKAFSQSSCLTLHRRVHTGEKPYKCSRCGKAFSQRANQKKHERIHSGEKPYTCDVCGRAFGLSAHLSQHQRVHTQEKPHCQDCHRAFHSCSALSKHQQLHSCKVTSSTAQSHLVTAESRTCEDIHRKSVIETNTLQTSPLNKF", "length": 797, "header": "tr|A0A9J7JZA8-1|A0A9J7JZA8_CRIGR Computationally mapped isoform of Zinc finger protein 473 isoform X5 OS=Cricetulus griseus OX=10029 GN=Znf473 PE=3 SV=1 CANONICAL=A0A9J7G9L8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K6Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8/entry#A0A9J7K6Q1-1", "sequence": { "sequence": "METLSEEELNFEAYIGESWLDSLLGDPESLARSDITNTESPTDCKSHEFESSLSPGPLFSTGEDAGMSDILPKNLTPVIVKESRSDFSYYLEQSQKDSIQGEEKLYKCSECGKSFNQSYHLLQHWIIHVRDNTPSRQDKERELSTGAFLLMRPVTQTSYKPCVCQECGKRFSQNMYLQWHQKVHTGESLCKTQCDNLEKPSKSHSGEPKKLLPSKGSNSAKWCKIQSSDQAKPPDSNSSDQKKLHKSQCDGSPSILHPQPTEHQKTPANTKFYVCKKCGKTFSQAFHLAGHQKVHTEKLYECPTCHQVFHVRKHFVQHRKTHFVKTVFECQECKKIFNQRSSLIEHQAVHTGEKPYKCTECGKAFNHSSTLKIHQRAHSGEKPYKCSECGRAFCRSTHLHEHQQIHSGHRPYQCPECVRSFSRPSHLIRHQLSHTTDKPFGCAKCKNTFSHKEQLVQHHKVHTIESLYECKQCGEHFICSSTLHCHMSVHTREDISQKVSGQNKCGKAFNHNRYVGQHENSHTKVTSSECNPCVETYNQSLQLPCHQSIIQVGIKPDECTEPDTSKRNSSVSKHQPSGSEQPFKCNSCNRTFSQDAQLFKHQLIHTGEKPFKCNECDRAFKQSNYLIQHQRIHTVKQHFECSECGKTFRQSSCLSKHQKIHTGEKPFKCGDCGKAFILGAQLTRHQRIHTGEKPYVCQECGKAFSQSSCLTLHRRVHTGEKPYKCSRCGKAFSQRANQKKHERIHSGEKPYTCDVCGRAFGLSAHLSQHQRVHTQEKPHCQDCHRAFHSCSALSKHQQLHSCKVTSSTAQSHLVTAESRTCEDIHRKSVIETNTLQTSPLNKF", "length": 843, "header": "tr|A0A9J7K6Q1-1|A0A9J7K6Q1_CRIGR Computationally mapped isoform of Zinc finger protein 473 isoform X4 OS=Cricetulus griseus OX=10029 GN=Znf473 PE=3 SV=1 CANONICAL=A0A9J7G9L8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G767", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G767" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G767", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G767" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769900", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769900", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8" } ], "pmid": "" }, { "name": "regulation of anatomical structure morphogenesis", "id": "GO:0022603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022603", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9L8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 710, "end_pos": 712, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G9L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9L8" }, { "id": "PS50157", "database": 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##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278982" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sh3glb2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B0", "locus": {} } ], "crossref": [ { "id": "A0A9J7G8B0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G8B0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07617", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07617", "database": "CDD", "categories": [ "Protein Classification" ] 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"MKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPSTPYGKTLIKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASALWNDEVDKAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLSPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS", "length": 391, "header": "tr|A0A9J7G8B0-1|A0A9J7G8B0_CRIGR Isoform 1 of Endophilin-B2 OS=Cricetulus griseus OX=10029 GN=Sh3glb2 PE=3 SV=1 CANONICAL=A0A9J7G8B0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B0/entry#A0A9J7H2G7-1", "sequence": { "sequence": "MKKLASDAGIFFTRAVQFTEEKFGQAEKTELDAHFENLLARADSTKNWTERILRQTEVLLQPNPSARVEEFLYEKLDRKVPSRVTNGELLAQYMAEAASELGPSTPYGKTLIKVSEAEKRLGAAERDFIHTASLSFLTPLRNFLEGDWKTISKERRLLQNRRLDLDACKARLKKAKAAEAKATTVPDFQETRPRNYILSASASAAEQELRVAQTEFDRQAEVTRLLLEGISSTHVNHLRCLHEFVKSQTTYYAQCYRHMLDLQKQLGRFPGTFVGTTEPASPPLSSTSPTTTAATMPVVPTGAGLSPPEEAALCLEEVAPPASGTRKARVLYDYEAADSSELALLADELITVYSLPGMDPDWLIGERGNKKGKVPVTYLELLS", "length": 383, "header": "tr|A0A9J7H2G7-1|A0A9J7H2G7_CRIGR Computationally mapped isoform of Endophilin-B2 OS=Cricetulus griseus OX=10029 GN=Sh3glb2 PE=3 SV=1 CANONICAL=A0A9J7G8B0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 309, "start_aa": "Thr", "end_pos": 309, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr309", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7D6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7D6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7D6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7D6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753400", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753400", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B0" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "membrane organization", "id": "GO:0061024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061024", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8B0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G8B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B0" }, { "id": "PS51021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAR", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 283, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G8B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B0" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 331, "end_pos": 391, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 309 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G7E3-1", "uniprot_ac": "A0A9J7G7E3", "uniprot_id": "A0A9J7G7E3_CRIGR", "mass": { "chemical_mass": 82723.0, "monoisotopic_mass": 82723.0 }, "refseq": { "ac": "XP_027275695", "name": "solute carrier organic anion transporter family member 4A1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275695" }, "gene_names": [ { "name": "Slco4a1", "type": "recommended", "evidence": [ { "id": "A0A9J7G7E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E3" } ] }, { "name": "Slco4a1", "type": "synonym", "evidence": [ { "id": "XP_027275695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275695" } ] } ], "protein_names": [ { "name": "Solute carrier organic anion transporter family member", "type": "recommended", "evidence": [ { "id": "A0A9J7G7E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E3/entry#names_and_taxonomy" } ] }, { "name": "solute carrier organic anion transporter family member 4A1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027275695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275695" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275695", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275695" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slco4a1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E3", "locus": {} } ], "crossref": [ { "id": "A0A9J7G7E3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G7E3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756146", "url": "https://www.ncbi.nlm.nih.gov/gene/100756146", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756146", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756146", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LLIYTDW", "url": "https://omabrowser.org/oma/group/LLIYTDW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G7E3", "url": "https://www.orthodb.org/?gene=A0A9J7G7E3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11388:SF100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11388:SF100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027275695", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275695", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LZU2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LZU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEARVGSARRPERRAQRGSRVRGKAASTESHLLRCKALCTRLEMPQHVMGDKPFLSLPKHLLTNASSATDSGCDTPPSSRASPASLRSAHSPLGSSSQPLFEPQVGKRRSQTAREVQYMSAGPKNTLCGWRAFTPKCLQVFNTPKGFLFFLCAASFLQGMTVNGFINTVITSIEQRFDLHSYQSGLIASSYDIAACLCLTFVSYFGGNGHKPRWLGWGVLVLGIGSLVFALPHFTAGRYEVEMDEGVGVGTGACLANGSHVECMDSGLSSYRLVFMLGQLLHGVGATPLYTLGVTYLDENVKSNYSPIYIAIFYTAAILGPAAGYLIGGAMLNIYTEVSQRTDLTTDSPLWVGAWWIGFVGAGITAFLIAIPILGYPRQLPGSQRYIVMRAAEKQQLKDHSHRTVSNPAFGKTVRDLPLSIWLLLRNPTFILLCLAGATEATLIAGMSTFGPKFFEAQFSLSASEAATLFGYLVVPAGGGGTLLGGFLVNRFKLRGSGIIRFCLFCTLTSLLAFFVFLTHCPNMPMAGVTTSYVGSPLPEGHLDLKAACNAIYCCQEEHYSPLCGSDGTMYYSPCYAGCPAGAETGPSGQKIYRGCSCILQNVSSGLGNATAGKCTSTCQRKPLLLALVFVVIIFTFLSSIPALTATLRCVCDQQRSFALGIQWIVVRTLGSIPGPIAFGWVIDKACLLWQDQCGHQGSCFVYRNEAMSRYMLIAGLTFKVLGFLFFVTAYFLYKSPSVSSDGLETSLPSQSSASDNPTEQLQSNV", "length": 767, "header": "tr|A0A9J7G7E3-1|A0A9J7G7E3_CRIGR Isoform 1 of Solute carrier organic anion transporter family member OS=Cricetulus griseus OX=10029 GN=Slco4a1 PE=3 SV=1 CANONICAL=A0A9J7G7E3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LZU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E3/entry#A0A8C2LZU2-1", "sequence": { "sequence": "MPQHVMGDKPFLSLPKHLLTNASSATDSGCDTPPSSRASPASLRSAHSPLGSSSQPLFEPQVGKRRSQTAREVQYMSAGPKNTLCGWRAFTPKCLQVFNTPKGFLFFLCAASFLQGMTVNGFINTVITSIEQRFDLHSYQSGLIASSYDIAACLCLTFVSYFGGNGHKPRWLGWGVLVLGIGSLVFALPHFTAGRYEVEMDEGVGVGTGACLANGSHVECMDSGLSSYRLVFMLGQLLHGVGATPLYTLGVTYLDENVKSNYSPIYIAIFYTAAILGPAAGYLIGGAMLNIYTEVSQRTDLTTDSPLWVGAWWIGFVGAGITAFLIAIPILGYPRQLPGSQRYIVMRAAEKQQLKDHSHRTVSNPAFGKTVRDLPLSIWLLLRNPTFILLCLAGATEATLIAGMSTFGPKFFEAQFSLSASEAATLFGYLVVPAGGGGTLLGGFLVNRFKLRGSGIIRFCLFCTLTSLLAFFVFLTHCPNMPMAGVTTSYVGSPLPEGHLDLKAACNAIYCCQEEHYSPLCGSDGTMYYSPCYAGCPAGAETGPSGQKIYRGCSCILQNVSSGLGNATAGKCTSTCQRKPLLLALVFVVIIFTFLSSIPALTATLRCVCDQQRSFALGIQWIVVRTLGSIPGPIAFGWVIDKACLLWQDQCGHQGSCFVYRNEAMSRYMLIAGLTFKVLGFLFFVTAYFLYKSPSVSSDGLETSLPSQSSASDNPTEQLQSNV", "length": 723, "header": "tr|A0A8C2LZU2-1|A0A8C2LZU2_CRIGR Computationally mapped isoform of Solute carrier organic anion transporter family member OS=Cricetulus griseus OX=10029 GN=Slco4a1 PE=3 SV=1 CANONICAL=A0A9J7G7E3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7E3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E3/entry#A0A9J7G7E3-1", "sequence": { "sequence": "MNEARVGSARRPERRAQRGSRVRGKAASTESHLLRCKALCTRLEMPQHVMGDKPFLSLPKHLLTNASSATDSGCDTPPSSRASPASLRSAHSPLGSSSQPLFEPQVGKRRSQTAREVQYMSAGPKNTLCGWRAFTPKCLQVFNTPKGFLFFLCAASFLQGMTVNGFINTVITSIEQRFDLHSYQSGLIASSYDIAACLCLTFVSYFGGNGHKPRWLGWGVLVLGIGSLVFALPHFTAGRYEVEMDEGVGVGTGACLANGSHVECMDSGLSSYRLVFMLGQLLHGVGATPLYTLGVTYLDENVKSNYSPIYIAIFYTAAILGPAAGYLIGGAMLNIYTEVSQRTDLTTDSPLWVGAWWIGFVGAGITAFLIAIPILGYPRQLPGSQRYIVMRAAEKQQLKDHSHRTVSNPAFGKTVRDLPLSIWLLLRNPTFILLCLAGATEATLIAGMSTFGPKFFEAQFSLSASEAATLFGYLVVPAGGGGTLLGGFLVNRFKLRGSGIIRFCLFCTLTSLLAFFVFLTHCPNMPMAGVTTSYVGSPLPEGHLDLKAACNAIYCCQEEHYSPLCGSDGTMYYSPCYAGCPAGAETGPSGQKIYRGCSCILQNVSSGLGNATAGKCTSTCQRKPLLLALVFVVIIFTFLSSIPALTATLRCVCDQQRSFALGIQWIVVRTLGSIPGPIAFGWVIDKACLLWQDQCGHQGSCFVYRNEAMSRYMLIAGLTFKVLGFLFFVTAYFLYKSPSVSSDGLETSLPSQSSASDNPTEQLQSNV", "length": 767, "header": "tr|A0A9J7G7E3-1|A0A9J7G7E3_CRIGR Isoform 1 of Solute carrier organic anion transporter family member OS=Cricetulus griseus OX=10029 GN=Slco4a1 PE=3 SV=1 CANONICAL=A0A9J7G7E3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7E3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756146", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756146", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZS46-1", "protein_name": "Solute carrier organic anion transporter family member", "gene_name": "SLCO4A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNEAGVGAERQSERGAQRGCRALGTIDPTAGAPPVLLHCRRCRASSKMPQHSVGDKPFVSMPQPVFPGPPLAANGSCDHTPPGRRASLCSPLSPSALRAAAHGPLDSSSQPLCQPEKHGPRAAAREVHYVAAGPGEACGWRAFAPACLQVFNTPCGFLLFLCAASFLQGMTVNGFINSVITSIERRFDLHSYQSGLTASSYDVAACLCLTFVSYFGGHGHKPRWLGWGVLVMGAGSLVFALPHFTTGPYEVQGDQVVGTCRANQSAPCGGRASSLSSYRLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSSSPVYLATFYTAAILGPAAGYLVGGALLNIYTEIGTRTELTTESPHWVGAWWVGFLGAGAAAFLIAVPILGYPRQLPGSQRYVVMRASETHQLKDSGHKAASNPDFGKTIRDLPLSIWLLLKNPTFILLCLAGATEATLIAGMSTFGPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKLKLRGSGTIKFCLLCTLASGLTTLAFLTHCPNVPMAGVTVSYNGSLLPEGHLELTAACNAHCGCWAGHYTPVCGSDGLMYHSPCHAGCTEAATPGPGGQMVYRDCSCVPQNLSSGFGHATAGKCTSTCQRKPLLLVFIFVVIIFTFLSSIPALTATLRCVCDRQRSFALGIQWIVVRTLGGIPGPIAFGWVIDKSCLLWQDQCGQQGSCFVYQNSAMSRYMLITGLLYKTSSDRATREKAICVALNKSDRSWASSSSPLPASSTSPCRRLQMAWKPLCPASPRPPTIPQTFREPPRPSSSRAMSDRSPARQGQGPPGSASPELCLISRRKG", "length": 829 }, "evidence": [ { "id": "A0A9J7G7E3", "url": "https://omabrowser.org/oma/group/A0A9J7G7E3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BPV8-1", "protein_name": "Solute carrier organic anion transporter family member", "gene_name": "SLCO4A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKREWAPSGRQSVVSSAAARTSGLLIQPLESRVSVPTAITATPSAEMPQHSTGDKPLVSKPQLVFPGPASGTDSECDRTPPSRRVSLSAPLSQPLCQPEKCGPRAAQEVCYVAAGQPGEACGWRAFAPMCLQAFNTPQGFLLFLCVASFLQGMTVNGFINTVITSIERRYDLHSYQSGLIASSYDVAACLCLTFVSYFGGQGHKPRWLGWGVLVMGAGSLVFALPHFTAGRYEVQMDEVVGTCWANHSSTCKDGASGLSSYRLVFMLGQFLHGMGATPLYTLGVTYLDENVKSSYSPVYIATFYTAAILGPAAGYLVGGALLNIYTDISQQTQLTTESPLWVGAWWVGFLGAGAAAFLVAIPILGYPRQLPGSQRYVVMRASETYQLKDSSHKVTSNPDFGKTISDLPLSIWLLLKNPTFILLCLAGATEATLIASMSTFGPKFLESQFSLSASEAATLFGYLVVPAGGGGTFLGGFFVNKFKLRGSGIIKFCLLCTLVSLLASLIFLMHCPGVPMAGVTAGYNGSLLPEGHVELMAACNLHCSCQPEHYSPVCGSDGLMYYSPCYAGCLEMAVSSPGGQKVYRDCSCVPQNFSSGFGHATAGKCTSTCQRKPLLLVFIFVVIVFTFLSSIPALTATLRCVCDQQRSFALGIQWIVVRTLGSIPGPIAFGWVIDKACLLWQDQCGQQGSCFVYQNSAMSWYLLIAGLGYKVLGSIFFAIACFLYKSPPGSSDGLEASLPSQSSASDNPSDLQEAPSALQIQSDI", "length": 764 }, "evidence": [ { "id": "A0A9J7G7E3", "url": "https://omabrowser.org/oma/group/A0A9J7G7E3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K078-1", "protein_name": "Solute carrier organic anion transporter family member 4A1", "gene_name": "Slco4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPQHAMGDTHFLSLPKHLFTSTSSATDSGCDTPPSSRASPASLRSAHGTLGSSSQPLFEPQAEKRSSQTAREVQYVSSGPQNSLCGWQAFTPKCLQVFNTPKGFLFFLCAASFLQGMTVNGFINTVITSIERRFDLHSYQSGLIASSYDIAACLCLTFVSYFGGNGHKPRWLGWGVLVLGIGSLVFALPHFTAGRYEVEMDEGLGTGTCLTNQSHVECKDSASGLSNYRLIFMLGQLLHGVGATPLYTLGVTYLDENVKSSYSPIYIAIFYTAAILGPAAGYLIGGAMLNVYTEVGQRTELTTDSPLWVGAWWIGFLGTGIAAFLIAIPILGYPRQLPGSQRYVVMRAAETQQLKDHSRGAVSNPAFGKTVRDLPLSIWLLLRNPTFILLCLAGATEATLIAGMSTFGPKFFEAQFSLSASEAATLFGYLVVPAGGGGTLLGGFLVNKFKLRGSGIIRFCLFCTLTSLLAFFVFLMHCPNVHMAGVTTGYVGSLLPKGQLDLKAACNAIYCCQPKHYSPLCGSDGTMYYSPCYAGCPADAETDLGGQKVYRGCSCILEKASSGWGNATAGKCASTCQSKPFLLVLVFVVIIFTFLSSIPALTATLRCVSDRQRSFALGIQWIVVRTLGSIPGPIAFGWVIDKACLLWQDQCGHQGSCFVYENEAMSRYMLIAGLTFKVLGFLFFVAAYFLYKSPSVSSDGLEASLPSQSSASDSPTEQLQSNV", "length": 723 }, "evidence": [ { "id": "A0A9J7G7E3", "url": "https://omabrowser.org/oma/group/A0A9J7G7E3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96BD0-1", "protein_name": "Solute carrier organic anion 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This record is derived from a genomic sequence (NW_003614789.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509918" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cst11", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E5", "locus": {} } ], "crossref": [ { "id": "A0A9J7G7E5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G7E5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763132", "url": "https://www.ncbi.nlm.nih.gov/gene/100763132", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763132", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763132", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G7E5", "url": "https://www.orthodb.org/?gene=A0A9J7G7E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47886", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47886", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47886:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47886:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509918", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G7E5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMARPWKASQLLLAILVALVAFSYQQKRKTFISVREVNALEPPVPDTLDYVTDAYNKESEDVYNFRILRILKIEKRVTDHLEFRIRVEMRRTTCFKTEKSTCDVQEGELYKQIQCYFSVYVIPWFERYKILKKNCTNS", "length": 138, "header": "tr|A0A9J7G7E5-1|A0A9J7G7E5_CRIGR Isoform 1 of Cystatin-11 OS=Cricetulus griseus OX=10029 GN=Cst11 PE=3 SV=1 CANONICAL=A0A9J7G7E5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G7E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E5/entry#A0A9J7G7E5-1", "sequence": { "sequence": "MMARPWKASQLLLAILVALVAFSYQQKRKTFISVREVNALEPPVPDTLDYVTDAYNKESEDVYNFRILRILKIEKRVTDHLEFRIRVEMRRTTCFKTEKSTCDVQEGELYKQIQCYFSVYVIPWFERYKILKKNCTNS", "length": 138, "header": "tr|A0A9J7G7E5-1|A0A9J7G7E5_CRIGR Isoform 1 of Cystatin-11 OS=Cricetulus griseus OX=10029 GN=Cst11 PE=3 SV=1 CANONICAL=A0A9J7G7E5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278189" } ] }, { "annotation": "May play a role in regeneration of skeletal muscle.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7E6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E6#function" }, { "database": "UniProtKB", "id": "ARBA00037622", "url": "https://www.uniprot.org/uniprotkb/ARBA00037622#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7E6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7E6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pamr1", "url": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003512760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512760" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC107976983", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H5", "locus": {} } ], "crossref": [ { "id": "A0A9J7G7H5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G7H5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15226", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15226", "database": "CDD", "categories": [ "Protein 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"MDQINNTVVFEFVLLGLSSSWKTTIFLIYVFSLLYLSIILGNIFIVFLVITDTHLQSPMYFFLANLSLIDVGLSSTTIPKMISDLLKERKVISFHSCMTQMCSIHIIGGVEMVLLIAMAFDRYTAICKPLRYLSIMSPKTCISFVIAGWVTGVIHALSQFSFVINLPFCGPNKVDSFYCDFPRIIQLACADRDKFEFVVATNSGFMSMGTFFLLLLSYVFILVTVWKRSSGNLSKAFVTLSAHITVVVLFFTPCMFLYVWPFPTSSTDKYLFIVDFAVTPALNPVIYTLRNKDMKEAIKKLNK", "length": 303, "header": "tr|A0A9J7G7H5-1|A0A9J7G7H5_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC107976983 PE=3 SV=1 CANONICAL=A0A9J7G7H5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G7H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H5/entry#A0A9J7G7H5-1", "sequence": { "sequence": "MDQINNTVVFEFVLLGLSSSWKTTIFLIYVFSLLYLSIILGNIFIVFLVITDTHLQSPMYFFLANLSLIDVGLSSTTIPKMISDLLKERKVISFHSCMTQMCSIHIIGGVEMVLLIAMAFDRYTAICKPLRYLSIMSPKTCISFVIAGWVTGVIHALSQFSFVINLPFCGPNKVDSFYCDFPRIIQLACADRDKFEFVVATNSGFMSMGTFFLLLLSYVFILVTVWKRSSGNLSKAFVTLSAHITVVVLFFTPCMFLYVWPFPTSSTDKYLFIVDFAVTPALNPVIYTLRNKDMKEAIKKLNK", "length": 303, "header": "tr|A0A9J7G7H5-1|A0A9J7G7H5_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC107976983 PE=3 SV=1 CANONICAL=A0A9J7G7H5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 264, "start_aa": "Thr", "end_pos": 264, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr264", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 279, "start_aa": "Thr", "end_pos": 279, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr279", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:107976983", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107976983", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G7H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H5" }, { "id": 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274929" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccdc88c", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6", "locus": {} } ], "crossref": [ { "id": "cd22228", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22228", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753852", "url": "https://www.ncbi.nlm.nih.gov/gene/100753852", "database": "GeneID", "categories": [ "Genome 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"MDVTVSQLVEMFLQSPLVTWVKTFGPFGSGHQDNLTLYMDLVDGIFLNQIMLQIDPRPNNQRINKHVNNDVNLRIQNLSILVRNIKTYYQEVLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKVLLLVLGCAVQCERKEEFIERIKQLDIETQAGIVAHIQEVTHNQENVFDLQWLELPDVAPEELEALSRNMVFHLRRLIDERDECTELIVDLTQERDYLQAQHPPSPGKFSSPDSTPSPTSSLSSEDKQHLAVELADTKARLRRVRQELEEKTEQLSDTRHEVDQLVLELQKAKQDNIQLAADARSARAYRDELDSLREKANRVERLEMELIRCKEKLHDVDFYKARMEELREDNIILIETKAMLEEQLAAARARSDKVHELEKENLQLKSKLHDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLALEENSLKCGELEKENQQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMEALKADKARQIKDLEQEKGHLHQAVWSLRERPQVNSTKDVEKENRALHQAVSEAGSKVSQLELEKKQLYRDLEEAKEKGERAEVLEKELHRLEKENEQLAEKVTSLKTVTEKVEALEHKSQGLELENGTLRKSLDTLQNVSVQLEGLERDNKQLDQENLELRKMVEAMRFTSAKMAQIESENQQLEQEKEDLRRSVELLKTLSKKSERLELSYQNVSAENLRLQHSLESSSHKSQALERELGELEAERQSLKRDLETLQLANKQLEGAEKDKKALEQEVAQLEKDKKLLEKETRRLWQQVELKDAVLDDSAAKLSAAEKESRALDKELARCRDAASKLKELEKDNRDLTKQVTVHTETLSTLREDLVLEKLKSQQLTSELEKLSQELEKVGLSKDLLLQEANSHDDTKCKILEGKNESALKTTLAMKEEKIAFLQAQVEEKESLNHQLQIELQMVKDEREQLRQTQEDRTQAQKVLKHPDGKVVASHQEKEAWEPGHKEATMELLRVKDRAIELERSNAALQAEKQLLKEQLQHLETQNVAFSSQILTLQKQSTFLQEHTTALQTQTAKLQVENSTLSSQNAALGAQYTMLQSQQTAKEAEHEALQQQREQLAAAYEGLFQDHEHLGALYERQSSEYEALIRQHSCLKTLHRNLELEHKELGERHGDLQRQKAELEELEKVLRAEREALQQEQRTNAVATSENQRLRGELDRVSFLHHQLKGEYEELHAHTKELKTSLNNSQLELNRWQARFDELKEQHQNMDISLTKLDNHCELLSRLKGNLEEENHHLLSQIQLLNQQNQMLLEQNMENKEQYHEEQKQYIDKLNALRRHKEKLEEKIMDQYKFYDPAPKKKNHWIGAKALVKFMKPKKEGSRERLKAATDSPTWQPEPWDPASPSASQTVRSQPENSDNPTSISNCAEERGTHNGPVGKGPGDLKPNRGSPRGGSVDRTDTPTDPAVKSWPSEPGSRTFSTSVTMSAPSSSTPVPKHPGRTKGCNSDDNLFEPSMEPEGPYPRQPASRPNSLESSRNTSSNSSPLSLKGSSDRLHGRCESFGSSDLIPSRDTTTLSRDAGTPGRGILSRHEYPPLRNGPVPQENIQKRGAAPAHTGARPRSASPSSEMVTLEEFLEESNRGSPTHDTAGCRNDLLSDYFRKAHDPPAMGGQPRPPARKDGAKMPTSFVAPTIKMPVSSSEGQQLKPGHYVKPNLRPSEAEALAGVPSRQVQPPQSLSLGRPRQGAMPPTCHMPASRSASLSRTFSLASADLLRASGPEACRSESPQKPGCPEATGTRDTGSHSLQGSHSLARERTPLVAKTDSSSPGPGTRGRPLDTRRFSLAPPKEERLAPLQQSATAPALATGCNSGSNPPIQHFSPTVAPAVRTKPKVPPHSGEVATVAPVRSGLSVSEGDGGPGHGYSEGLLTKSPGRSPDLAPHVSRGPDDFSQGSSSKSTPASPEPGGDPQTVWYEYGCV", "length": 2014, "header": "tr|A0A9J7G7H6-1|A0A9J7G7H6_CRIGR Isoform 1 of Protein Daple isoform X2 OS=Cricetulus griseus OX=10029 GN=Ccdc88c PE=3 SV=1 CANONICAL=A0A9J7G7H6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H360-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6/entry#A0A9J7H360-1", "sequence": { "sequence": "MDVTVSQLVEMFLQSPLVTWVKTFGPFGSGHQDNLTLYMDLVDGIFLNQIMLQIDPRPNNQRINKHVNNDVNLRIQNLSILVRNIKTYYQEVLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKVLLLVLGCAVQCERKEEFIERIKQLDIETQAGIVAHIQEVTHNQENVFDLQWLELPDVAPEELEALSRNMVFHLRRLIDERDECTELIVDLTQERDYLQAQHPPSPGKFSSPDSTPSPTSSLSSEDKQHLAVELADTKARLRRVRQELEEKTEQLSDTRHEVDQLVLELQKAKQDNIQLAADARSARAYRDELDSLREKANRVERLEMELIRCKEKLHDVDFYKARMEELREDNIILIETKAMLEEQLAAARARSDKVHELEKENLQLKSKLHDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLALEENSLKCGELEKENQQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMEALKADKARQIKDLEQEKGHLHQAVWSLRERPQVNSTKDVEKENRALHQAVSEAGSKVSQLELEKKQLYRDLEEAKEKGERAEVLEKELHRLEKENEQLAEKVTSLKTVTEKVEALEHKSQGLELENGTLRKSLDTLQNVSVQLEGLERDNKQLDQENLELRKMVEAMRFTSAKMAQIESENQQLEQEKEDLRRSVELLKTLSKKSERLELSYQNVSAENLRLQHSLESSSHKSQALERELGELEAERQSLKRDLETLQLANKQLEGAEKDKKALEQEVAQLEKDKKLLEKETRRLWQQVELKDAVLDDSAAKLSAAEKESRALDKELARCRDAASKLKELEKDNRDLTKQVTVHTETLSTLREDLVLEKLKSQQLTSELEKLSQELEKVGLSKDLLLQEANSHDDTKCKILEGKNESALKTTLAMKEEKIAFLQAQVEEKESLNHQLQIELQMVKDEREQLRQTQEDRTQAQKVLKHPDGKVVASHQEKEAWEPGHKEATMELLRVKDRAIELERSNAALQAEKQLLKEQLQHLETQNVAFSSQILTLQKQSTFLQEHTTALQTQTAKLQVENSTLSSQNAALGAQYTMLQSQQTAKEAEHEALQQQREQLAAAYEGLFQDHEHLGALYERQSSEYEALIRQHSCLKTLHRNLELEHKELGERHGDLQRQKAELEELEKVLRAEREALQQEQRTNAVATSENQRLRGELDRVSFLHHQLKGEYEELHAHTKELKTSLNNSQLELNRWQARFDELKEQHQNMDISLTKLDNHCELLSRLKGNLEEENHHLLSQIQLLNQQNQMLLEQNMENKEQYHEEQKQYIDKLNALRRHKEKLEEKIMDQYKFYDPAPKKKNHWIGAKALVKFMKPKKEGSRERLKAATDSPTWQPEPWDPASPSASQTVRSQPENSDNPTSISNCAEERGTHNGPVGKGCNSDDNLFEPSMEPEGPYPRQPASRPNSLESSRNTSSNSSPLSLKGSSDRLHGRCESFGSSDLIPSRDTTTLSRDAGTPGRGILSRHEYPPLRNGPVPQENIQKRGAAPAHTGARPRSASPSSEMVTLEEFLEESNRGSPTHDTAGCRNDLLSDYFRKAHDPPAMGGQPRPPARKDGAKMPTSFVAPTIKMPVSSSEGQQLKPGHYVKPNLRPSEAEALAGVPSRQVQPPQSLSLGRPRQGAMPPTCHMPASRSASLSRTFSLASADLLRASGPEACRSESPQKPGCPEATGTRDTGSHSLQGSHSLARERTPLVAKTDSSSPGPGTRGRPLDTRRFSLAPPKEERLAPLQQSATAPALATGCNSGSNPPIQHFSPTVAPAVRTKPKVPPHSGEVATVAPVRSGLSVSEGDGGPGHGYSEGLLTKSPGRSPDLAPHVSRGPDDFSQGSSSKSTPASPEPGGDPQTVWYEYGCV", "length": 1951, "header": "tr|A0A9J7H360-1|A0A9J7H360_CRIGR Computationally mapped isoform of Protein Daple isoform X3 OS=Cricetulus griseus OX=10029 GN=Ccdc88c PE=3 SV=1 CANONICAL=A0A9J7G7H6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 237, "start_aa": "Thr", "end_pos": 237, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr237", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 241, "start_aa": "Thr", "end_pos": 241, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr241", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753852", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753852", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "pmid": "" }, { "name": "cytoskeleton-dependent intracellular transport", "id": "GO:0030705", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030705", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "pmid": "" }, { "name": "dynein light intermediate chain binding", "id": "GO:0051959", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051959", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1119, "end_pos": 1121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1284, "end_pos": 1286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1575, "end_pos": 1577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1579, "end_pos": 1581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 472, "end_pos": 474, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 760, "end_pos": 762, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" }, { "start_pos": 961, "end_pos": 963, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G7H6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7H6" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 131, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 237, 241 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1119, "end_pos": 1121 }, { "start_pos": 1284, "end_pos": 1286 }, { "start_pos": 1575, "end_pos": 1577 }, { "start_pos": 1579, "end_pos": 1581 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 427, "end_pos": 429 }, { "start_pos": 472, "end_pos": 474 }, { "start_pos": 580, "end_pos": 582 }, { "start_pos": 672, "end_pos": 674 }, { "start_pos": 684, "end_pos": 686 }, { "start_pos": 760, "end_pos": 762 }, { "start_pos": 77, "end_pos": 79 }, { "start_pos": 961, "end_pos": 963 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", 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"common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765781", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I5", "locus": {} } ], "crossref": [ { "id": "A0A9J7G7I5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G7I5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04329", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04329", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04462", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04462", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765781", "url": "https://www.ncbi.nlm.nih.gov/gene/100765781", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005576", "url": 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This record is derived from a genomic sequence (NW_003613649.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003497509.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497509" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7I9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rag2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9", "locus": {} } ], "crossref": [ { "id": "A0A9J7G7I9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G7I9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15569", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15569", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754577", "url": "https://www.ncbi.nlm.nih.gov/gene/100754577", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754577", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754577", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G7I9", "url": "https://www.orthodb.org/?gene=A0A9J7G7I9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10960", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10960", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10960:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10960:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13341", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13341", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497509", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G7I9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRYSKLMRFILLSDKRPTHNKKMSLQMVTVGHNIALIQPGFSLMNFDGQVFFFGQKGWPKRSCPTGVFHFDIKQNHLKLKPAVFSKDSCYLPPLRYPATCSYKSSLESEQHQYIIHGGKTPNNELSDKIYIMSVACKNNKKVTFRCTEKDLVGDVPEARYGHSIDVVYSRGKSMGVLFGGRSYMPSTQRTTEKWNSVADCLPHIFLVDFEFGCATSYVLPELQDGLSFHVSIARNDTIYILGGHSLANNIRPANLYRIRVDLPLGSPAVNCTVLPGGISVSSAILTQTNNNEFVIVGGYQIENQKRMVCNIVSLGDNTIEISEMETPDWTPDIKHSKIWFGSSMGNGTVFLGIPGDNKQAMSEAFYFYMLKCSEDDVSEEQKIFTNSQTSTEDPGDSTPFEDSEEFCFSTEATSFDGDDEFDTYNEDDEDDESVTGYWITCCPTCDVDINTWVPFYSTELNKPAMIYCSHGEGHWVHAQCMDLAERTLIHLSEGSNKYYCNEHIQIARALQTPKRGLPLQKPPMKSLHKKGSGKVLTPAKKSFLRRLFD", "length": 550, "header": "tr|A0A9J7G7I9-1|A0A9J7G7I9_CRIGR Isoform 1 of V(D)J recombination-activating protein 2 OS=Cricetulus griseus OX=10029 GN=Rag2 PE=3 SV=1 CANONICAL=A0A9J7G7I9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G7I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9/entry#A0A9J7G7I9-1", "sequence": { "sequence": "MKRYSKLMRFILLSDKRPTHNKKMSLQMVTVGHNIALIQPGFSLMNFDGQVFFFGQKGWPKRSCPTGVFHFDIKQNHLKLKPAVFSKDSCYLPPLRYPATCSYKSSLESEQHQYIIHGGKTPNNELSDKIYIMSVACKNNKKVTFRCTEKDLVGDVPEARYGHSIDVVYSRGKSMGVLFGGRSYMPSTQRTTEKWNSVADCLPHIFLVDFEFGCATSYVLPELQDGLSFHVSIARNDTIYILGGHSLANNIRPANLYRIRVDLPLGSPAVNCTVLPGGISVSSAILTQTNNNEFVIVGGYQIENQKRMVCNIVSLGDNTIEISEMETPDWTPDIKHSKIWFGSSMGNGTVFLGIPGDNKQAMSEAFYFYMLKCSEDDVSEEQKIFTNSQTSTEDPGDSTPFEDSEEFCFSTEATSFDGDDEFDTYNEDDEDDESVTGYWITCCPTCDVDINTWVPFYSTELNKPAMIYCSHGEGHWVHAQCMDLAERTLIHLSEGSNKYYCNEHIQIARALQTPKRGLPLQKPPMKSLHKKGSGKVLTPAKKSFLRRLFD", "length": 550, "header": "tr|A0A9J7G7I9-1|A0A9J7G7I9_CRIGR Isoform 1 of V(D)J recombination-activating protein 2 OS=Cricetulus griseus OX=10029 GN=Rag2 PE=3 SV=1 CANONICAL=A0A9J7G7I9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7I9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7I9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754577", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754577", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7I9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" } ], "pmid": "" }, { "name": "DNA recombinase complex", "id": "GO:0097519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097519", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7I9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7I9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7I9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7I9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" } ], "pmid": "" }, { "name": "V(D)J recombination", "id": "GO:0033151", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033151", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7I9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G7I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" }, { "id": "PF13341", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13341" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Recombination activating protein 2 PHD", "eco_id": "ECO_0000259", "start_pos": 437, "end_pos": 514, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A9J7G7I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9#function" }, { "id": "A0A9J7G7I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9" }, { "id": "PIRSR604321-1", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR604321-1" } ], "binding_site_uniprot": 442, "amino_acid": "Cys", "chebi_lig_id": "CHEBI_29105", "ligand": "Zn(2+)", "ligand_label": "1", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 442, "end_pos": 442, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G7I9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7I9#function" }, { "id": "A0A9J7G7I9", "database": "UniProtKB", "url": 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613798.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003500589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500589" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7M1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7M1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ncoa3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7M1", "locus": {} } ], "crossref": [ { "id": "cd00130", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00130", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774568", "url": "https://www.ncbi.nlm.nih.gov/gene/100774568", "database": "GeneID", "categories": [ "Genome 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[ "Protein Classification", "Other" ] }, { "id": "PF07469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16279", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16279", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23172", "url": 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"MSGLGESSLDPLATESRKRKLPCDAPGQGLAYSGEKWRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISSDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYSILHEQDRKDFLKHLPKSTVNGVSWTNETQRQKSHTFNCRMLMKTHDILEDMSASPETRQRYETMQCFALSQPRAMLEEGEDLQCCMICVARRVTTGERTLPSSPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDTIRRCIQRFFSPNDGQSWSQKRHYQEAYIHGHAETPVYRFSLADGTIVSAQTKSKLFRNPVTNDRHGFISTHFLQREQNGYRPNPNSVGQGIRPPAAGCGMNMSPNQSGQTLGSRTYGVADPSNAGQMGGARYGPSNNIASLTPGQSLQSPSSYQNSSYGLNMSSPPHGSPGLGPNQQNIMISPRNRGSPKMASHQFSPVAGVHSPMGSAGAPGSHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMSVNQPSKGGRQDSKSPLGLYCEQNPVESSVCQSNSREHPGEKESKESSGEGSETQRGPLESKGHKKLLQLLTCSSDDRGHSSVTNSPLDSNCKDSSTSVTSPSGVSSSTSGAVSSTSNVHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSTAPCGGEGNARQEQLSPKKKENNALLRYLLDRDDPSDALAKELQPQADVGDSKLSQCSSSTNPSSSQDKDSKIKTETSEEVSGDLDNLDAILGDLTSSEFYNNPVSTNGTHPGTKQQMFAGPSSLGLRSPQPVQPVRPPYNRAVSLDSPVSVGSGPPVKNVSAFPVLQKQPTLAGNPRVMDSQENYGASMGGPNRNVAVAVNQTSSPGEWSLANSKASRMEPMGSSPLGRTGDYSAALPRPAMGGSVPTLPLRPNRIPGARPTLQQQQQQQQQMLQMRTGEIPMGMGVNPYGQAAAPSNQPGSWPEGMLPMEQGPHGTQNRPLLRNPLEDLLGPPSNAEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEAKQDVFQGQEAAVMMDQKAALYGQTYPAQGPPMQGGFNLQGQSPSFNSMMNQISQQGSFPLQGMHPRASMVRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALEMKMENPTGGAAVMRPMMQPQQAFFNAQMAAQQKRELMNHHLQQQRMAMMMSQPQPQAFSPPPNVTASPSMDGVLAGSAMPQAPPQQFPYPTNYGMGQPPDPAFGRVSSPPNAMMSSRMGPSQNAMVQHPQTAPMYQSSEMKGWPSGNLARNSSFPQQQFAPQGKPAAYNMVHMNNSGGHLGQMNMTPMSMSGMPMGPDQKYC", 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"MSGLGESSLDPLATESRKRKLPCDAPGQGLAYSGEKWRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISSDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYSILHEQDRKDFLKHLPKSTVNGVSWTNETQRQKSHTFNCRMLMKTHDILEDMSASPETRQRYETMQCFALSQPRAMLEEGEDLQCCMICVARRVTTGERTLPSSPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDTIRRCIQRFFSPNDGQSWSQKRHYQEAYIHGHAETPVYRFSLADGTIVSAQTKSKLFRNPVTNDRHGFISTHFLQREQNGYRPNPNSVGQGIRPPAAGCGMNMSPNQSGQTLGSRTYGVADPSNAGQMGGARYGPSNNIASLTPGQSLQSPSSYQNSSYGLNMSSPPHGSPGLGPNQQNIMISPRNRGSPKMASHQFSPVAGVHSPMGSAGAPGSHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMSVNQPSKGGRQDSKSPLGLYCEQNPVESSVCQSNSREHPGEKESKESSGEGSETQRGPLESKGHKKLLQLLTCSSDDRGHSSVTNSPLDSNCKDSSTSVTSPSGVSSSTSGAVSSTSNVHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSTAPCGGEGNARQEQLSPKKKENNALLRYLLDRDDPSDALAKELQPQADVGDSKLSQCSSSTNPSSSQDKDSKIKTETSEEVSGDLDNLDAILGDLTSSEFYNNPVSTNGTHPGTKQQMFAGPSSLGLRSPQPVQPVRPPYNRAVSLDSPVSVGSGPPVKNVSAFPVLQKQPTLAGNPRVMDSQENYGASMGGPNRNVAVAVNQTSSPGEWSLANSKASRMEPMGSSPLGRTGDYSAALPRPAMGGSVPTLPLRPNRIPGARPTLQQQQQQQQQMLQMRTGEIPMGMGVNPYGQAAAPSNQPGSWPEGMLPMEQGPHGTQNRPLLRNPLEDLLGPPSNAEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEAKQDVFQGQEAAVMMDQKAALYGQTYPAQGPPMQGGFNLQGQSPSFNSMMNQISQQGSFPLQGMHPRASMVRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALEMKMENPTGGAAVMRPMMQPQAFFNAQMAAQQKRELMNHHLQQQRMAMMMSQPQPQAFSPPPNVTASPSMDGVLAGSAMPQAPPQQFPYPTNYGMGQPPDPAFGRVSSPPNAMMSSRMGPSQNAMVQHPQTAPMYQSSEMKGWPSGNLARNSSFPQQQFAPQGKPAAYNMVHMNNSGGHLGQMNMTPMSMSGMPMGPDQKYC", "length": 1394, "header": "tr|A0A8C2LSF6-1|A0A8C2LSF6_CRIGR Computationally mapped isoform of Nuclear receptor coactivator OS=Cricetulus griseus OX=10029 GN=Ncoa3 PE=3 SV=1 CANONICAL=A0A9J7G7M1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7M1/entry#A0A9J7G7M1-1", "sequence": { "sequence": "MSGLGESSLDPLATESRKRKLPCDAPGQGLAYSGEKWRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISSDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYSILHEQDRKDFLKHLPKSTVNGVSWTNETQRQKSHTFNCRMLMKTHDILEDMSASPETRQRYETMQCFALSQPRAMLEEGEDLQCCMICVARRVTTGERTLPSSPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDTIRRCIQRFFSPNDGQSWSQKRHYQEAYIHGHAETPVYRFSLADGTIVSAQTKSKLFRNPVTNDRHGFISTHFLQREQNGYRPNPNSVGQGIRPPAAGCGMNMSPNQSGQTLGSRTYGVADPSNAGQMGGARYGPSNNIASLTPGQSLQSPSSYQNSSYGLNMSSPPHGSPGLGPNQQNIMISPRNRGSPKMASHQFSPVAGVHSPMGSAGAPGSHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMSVNQPSKGGRQDSKSPLGLYCEQNPVESSVCQSNSREHPGEKESKESSGEGSETQRGPLESKGHKKLLQLLTCSSDDRGHSSVTNSPLDSNCKDSSTSVTSPSGVSSSTSGAVSSTSNVHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSTAPCGGEGNARQEQLSPKKKENNALLRYLLDRDDPSDALAKELQPQADVGDSKLSQCSSSTNPSSSQDKDSKIKTETSEEVSGDLDNLDAILGDLTSSEFYNNPVSTNGTHPGTKQQMFAGPSSLGLRSPQPVQPVRPPYNRAVSLDSPVSVGSGPPVKNVSAFPVLQKQPTLAGNPRVMDSQENYGASMGGPNRNVAVAVNQTSSPGEWSLANSKASRMEPMGSSPLGRTGDYSAALPRPAMGGSVPTLPLRPNRIPGARPTLQQQQQQQQQMLQMRTGEIPMGMGVNPYGQAAAPSNQPGSWPEGMLPMEQGPHGTQNRPLLRNPLEDLLGPPSNAEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEAKQDVFQGQEAAVMMDQKAALYGQTYPAQGPPMQGGFNLQGQSPSFNSMMNQISQQGSFPLQGMHPRASMVRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALEMKMENPTGGAAVMRPMMQPQQAFFNAQMAAQQKRELMNHHLQQQRMAMMMSQPQPQAFSPPPNVTASPSMDGVLAGSAMPQAPPQQFPYPTNYGMGQPPDPAFGRVSSPPNAMMSSRMGPSQNAMVQHPQTAPMYQSSEMKGWPSGNLARNSSFPQQQFAPQGKPAAYNMVHMNNSGGHLGQMNMTPMSMSGMPMGPDQKYC", "length": 1395, "header": "tr|A0A9J7G7M1-1|A0A9J7G7M1_CRIGR Isoform 1 of Nuclear receptor coactivator OS=Cricetulus griseus OX=10029 GN=Ncoa3 PE=3 SV=1 CANONICAL=A0A9J7G7M1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7M1/entry#A0A9J7GAL8-1", "sequence": { "sequence": "MLMKTHDILEDMSASPETRQRYETMQCFALSQPRAMLEEGEDLQCCMICVARRVTTGERTLPSSPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDTIRRCIQRFFSPNDGQSWSQKRHYQEAYIHGHAETPVYRFSLADGTIVSAQTKSKLFRNPVTNDRHGFISTHFLQREQNGYRPNPNSVGQGIRPPAAGCGMNMSPNQSGQTLGSRTYGVADPSNAGQMGGARYGPSNNIASLTPGQSLQSPSSYQNSSYGLNMSSPPHGSPGLGPNQQNIMISPRNRGSPKMASHQFSPVAGVHSPMGSAGAPGSHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMSVNQPSKGGRQDSKSPLGLYCEQNPVESSVCQSNSREHPGEKESKESSGEGSETQRGPLESKGHKKLLQLLTCSSDDRGHSSVTNSPLDSNCKDSSTSVTSPSGVSSSTSGAVSSTSNVHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSTAPCGGEGNARQEQLSPKKKENNALLRYLLDRDDPSDALAKELQPQADVGDSKLSQCSSSTNPSSSQDKDSKIKTETSEEVSGDLDNLDAILGDLTSSEFYNNPVSTNGTHPGTKQQMFAGPSSLGLRSPQPVQPVRPPYNRAVSLDSPVSVGSGPPVKNVSAFPVLQKQPTLAGNPRVMDSQENYGASMGGPNRNVAVAVNQTSSPGEWSLANSKASRMEPMGSSPLGRTGDYSAALPRPAMGGSVPTLPLRPNRIPGARPTLQQQQQQQQQMLQMRTGEIPMGMGVNPYGQAAAPSNQPGSWPEGMLPMEQGPHGTQNRPLLRNPLEDLLGPPSNAEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEAKQDVFQGQEAAVMMDQKAALYGQTYPAQGPPMQGGFNLQGQSPSFNSMMNQISQQGSFPLQGMHPRASMVRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALEMKMENPTGGAAVMRPMMQPQQAFFNAQMAAQQKRELMNHHLQQQRMAMMMSQPQPQAFSPPPNVTASPSMDGVLAGSAMPQAPPQQFPYPTNYGMGQPPDPAFGRVSSPPNAMMSSRMGPSQNAMVQHPQTAPMYQSSEMKGWPSGNLARNSSFPQQQFAPQGKPAAYNMVHMNNSGGHLGQMNMTPMSMSGMPMGPDQKYC", "length": 1196, "header": "tr|A0A9J7GAL8-1|A0A9J7GAL8_CRIGR Computationally mapped isoform of Nuclear receptor coactivator 3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Ncoa3 PE=3 SV=1 CANONICAL=A0A9J7G7M1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JWG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7M1/entry#A0A9J7JWG6-1", "sequence": { "sequence": "MLQDRGKTISSDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYSILHEQDRKDFLKHLPKSTVNGVSWTNETQRQKSHTFNCRMLMKTHDILEDMSASPETRQRYETMQCFALSQPRAMLEEGEDLQCCMICVARRVTTGERTLPSSPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDTIRRCIQRFFSPNDGQSWSQKRHYQEAYIHGHAETPVYRFSLADGTIVSAQTKSKLFRNPVTNDRHGFISTHFLQREQNGYRPNPNSVGQGIRPPAAGCGMNMSPNQSGQTLGSRTYGVADPSNAGQMGGARYGPSNNIASLTPGQSLQSPSSYQNSSYGLNMSSPPHGSPGLGPNQQNIMISPRNRGSPKMASHQFSPVAGVHSPMGSAGAPGSHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMSVNQPSKGGRQDSKSPLGLYCEQNPVESSVCQSNSREHPGEKESKESSGEGSETQRGPLESKGHKKLLQLLTCSSDDRGHSSVTNSPLDSNCKDSSTSVTSPSGVSSSTSGAVSSTSNVHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSTAPCGGEGNARQEQLSPKKKENNALLRYLLDRDDPSDALAKELQPQADVGDSKLSQCSSSTNPSSSQDKDSKIKTETSEEVSGDLDNLDAILGDLTSSEFYNNPVSTNGTHPGTKQQMFAGPSSLGLRSPQPVQPVRPPYNRAVSLDSPVSVGSGPPVKNVSAFPVLQKQPTLAGNPRVMDSQENYGASMGGPNRNVAVAVNQTSSPGEWSLANSKASRMEPMGSSPLGRTGDYSAALPRPAMGGSVPTLPLRPNRIPGARPTLQQQQQQQQQMLQMRTGEIPMGMGVNPYGQAAAPSNQPGSWPEGMLPMEQGPHGTQNRPLLRNPLEDLLGPPSNAEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEAKQDVFQGQEAAVMMDQKAALYGQTYPAQGPPMQGGFNLQGQSPSFNSMMNQISQQGSFPLQGMHPRASMVRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALEMKMENPTGGAAVMRPMMQPQQAFFNAQMAAQQKRELMNHHLQQQRMAMMMSQPQPQAFSPPPNVTASPSMDGVLAGSAMPQAPPQQFPYPTNYGMGQPPDPAFGRVSSPPNAMMSSRMGPSQNAMVQHPQTAPMYQSSEMKGWPSGNLARNSSFPQQQFAPQGKPAAYNMVHMNNSGGHLGQMNMTPMSMSGMPMGPDQKYC", "length": 1314, "header": "tr|A0A9J7JWG6-1|A0A9J7JWG6_CRIGR Computationally mapped isoform of histone acetyltransferase OS=Cricetulus griseus OX=10029 GN=Ncoa3 PE=3 SV=1 CANONICAL=A0A9J7G7M1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K777-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7M1/entry#A0A9J7K777-1", "sequence": { "sequence": "MSGLGESSLDPLATESRKRKLPCDAPGQGLAYSGEKWRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISSDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYSILHEQDRKDFLKHLPKSTVNGVSWTNETQRQKSHTFNCRMLMKTHDILEDMSASPETRQRYETMQCFALSQPRAMLEEGEDLQCCMICVARRVTTGERTLPSSPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDTIRRCIQRFFSPNDGQSWSQKRHYQEAYIHGHAETPVYRFSLADGTIVSAQTKSKLFRNPVTNDRHGFISTHFLQREQNGYRPNPNSVGQGIRPPAAGCGMNMSPNQSGQTLGSRTYGVADPSNAGQMGGARYGPSNNIASLTPGQSLQSPSSYQNSSYGLNMSSPPHGSPGLGPNQQNIMISPRNRGSPKMASHQFSPVAGVHSPMGSAGAPGSHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMSVNQPSKGGRQDSKSPLGLYCEQNPVESSVCQSNSREHPGEKESKESSGEGSETQRGPLESKGHKKLLQLLTCSSDDRGHSSVTNSPLDSNCKDSSTSVTSPSGVSSSTSGAVSSTSNVHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSTAPCGGEGNARQEQLSPKKKENNALLRYLLDRDDPSDALAKELQPQADVGDSKLSQCSSSTNPSSSQDKDSKIKTETSEEVSGDLDNLDAILGDLTSSEFYNNPVSTNGTHPGTKQQMFAGPSSLGLRSPQPVQPVRPPYNRAVSLDSPVSVGSGPPVKNVSAFPVLQKQPTLAGNPRVMDSQENYGASMGGPNRNVAVAVNQTSSPGEWSLANSKASRMEPMGSSPLGRTGDYSAALPRPAMGGSVPTLPLRPNRIPGARPTLQQQQQQQQQMLQMRTGEIPMGMGVNPYGQAAAPSNQPGSWPEGMLPMEQGPHGTQNRPLLRNPLEDLLGPPSNAEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEAKQDVFQGQEAAVMMDQKAALYGQTYPAQGPPMQGGFNLQGQSPSFNSMMNQISQQGSFPLQGMHPRASMVRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALEMKMENPTGGAAVMRPMMQPQQAFFNAQMAAQQKRELMNHHLQQQRMAMMMSQPQPQAFSPPPNVTASPSMDGVLAGSAMPQAPPQQFPYPTNYGMGQPPDPAFGRVSSPPNAMMSSRMGPSQNAMVQHPQTAPMYQSSEMKGWPSGNLARNRNTADISLVGPIRRSLYK", "length": 1362, "header": "tr|A0A9J7K777-1|A0A9J7K777_CRIGR Computationally mapped isoform of Nuclear receptor coactivator 3 OS=Cricetulus griseus OX=10029 GN=Ncoa3 PE=3 SV=1 CANONICAL=A0A9J7G7M1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 254, "start_aa": "Thr", "end_pos": 254, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr254", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7M1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7M1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7M1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7M1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774568", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774568", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZYK0-1", "protein_name": "Nuclear receptor coactivator", "gene_name": "NCOA3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVRMSGLGESSLDSLTNESRKRKPLPCDTPGASLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKAVSNDDEVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYGILHEEDRKDFLKNLPKSSVNGVAWTNDAPRQKSHTFNCRMMVKTSHDLLEDVGSHQDTRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRIATAERVFPTNPESFITRHDLSGKLVNIDTNSLRSSMRPGFEDTIRRCIQRFLCHNDGQSWSNKRHYHEAYTQGHAETPLYRFSLADGTIVTAQTKSKVFRNPVTNDRHGFVSTHFLQREQNGYRPNPNTVGQNIRTTVAGNTNSVGLMNMSPGQGMPMQNRNYGMGDPSTVGQLNSSRYGGPGNMGPVNSGPGMQSSAYQSNSYGLNISSPPHGSPGLTSNQQNLMISTRNRGSPKMNSHQFSPVTGMHSPMGSASNTSNSTFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDSSPNVSIAQQNKANNQDSKSPSGLYCEQNQVESSICQSNSRDVLSEKDSKDGSLDASESQRGQSESKGHKKLLQLLTCSSDERGHSTASNSPLDSNCKESSTNVTSPSGVSSSTSGGVSSSSNVHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTYHDTSNTVPCGESTVKQEQLSPKKKENNALLRYLLDKDDVKDPLSKELKPKVENVDNKMGQCSSTTIPTSSQEKEMKIKTEPTEEMSGDLDNLDAILGDLTSSDFYNNAMSTSGNNFGMKQALFQGNASLTGMRSPQSVQAARPPFNRAMSLDSPVGSGASVRNVNAFSMLQKQNLMGGSPRMTENQESFGANIASTPSRGVSMNQHQSGDWGLPNSKVNRLEPTSSTSMLRQGAEFSASLPRPTAGGSMPGLPVRSNSIPGTRPMLQQQMMHMRSNEINIGMGGNPYGQTGPTSQPGSWPDSMLSMEQASRGLQNRQLVRNSLDDLLSAAPSVEGQNDERALLDQLHTLLSNTDVTSLEEIDRALGIPDLVNQGQTLEPKQDSFQGQESAVMMDQKPSLYGQPYQGQGTALPGGFSNIQGQQPSFNSVMNQMSQQNNFPLQSMHPRANAMRPRTNTPKQLRMQLQQRLQGQQFMNQTRQALEMKMENPGSSNSSVMRPVMQPQVGSQQQGFLNAQMVAQRNRELISHHFRQQRMAMMMQQQQPQAFSPPPNVTASGSMDSGLTGPPMAQVPPQQFSYPPNYGISQQPDPAYSRVSSPPNPMMASRIGPSQNPMMQHPQTAPMYQSPEMKGWPSGSMARSSSFPQQQFSHQGNPATYSMMHMNGSSGHIGQMNISTVPMSGMPMGPDQKYC", "length": 1404 }, "evidence": [ { "id": "A0A9J7G7M1", "url": "https://omabrowser.org/oma/group/A0A9J7G7M1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MVD0-1", "protein_name": "Nuclear receptor coactivator", "gene_name": "NCOA3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSGLGENALDPLAPDSRKRKLPCDPPGQGLACSGEKWRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKAITSDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNREGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNGVTWTNETQRQKSHTFNCRMLMKIPHDILEDINTSPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERAFPSSPESFITRHDLSGKVITIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYIHGHAETPLYRFSLADGTIVTAQTKSKLFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPAAGCNSSVGGMSMSPNPGLQMLSSRTYGLTDAGTAGQMSGARYGASGSIASMNPGPGMQSPSSYQNSTYGLNMSSPPHGSPGLGSSQQNIMISPRNRGSPKMASHQFSPVAGVHSPMGSSGNTVSHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMNITQPSKVNSQDSKSPLGLYCDQNPVESSMCQSNSRDHINDKESKESGVEGSENQRAPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKDSSISVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSTTSCVEGNVKQEQLSPKKKESNALLRYLLDRDDPSDTLAKELQPKVEGVDSKMSQCSSSAIPSSSQEKDAKIKTETNEEGSGDLDNLDAILGDLTNSDFYNNSIPTSGSNLGTKPQMFQGANSLGLRSPQPVQSVRPPYNRAVSLDSPVSVGSSPPVKNIGAFPMLPKQPMLGGNPRMMDNQENYGSNMGGPNRNVTVNQAPSSGDWGLPSSKASRMEPVNSNAMGRPGTDYNASLPRPAMGGSMPAMPLRSNSIPGARPVMQQQQQQQPQPQMLQMRPGEIPMGMGVSPYGQAAPSNQPGSWPDGMLSMEQGPHGTQNRPILRNSLDDLLGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMEQKAALYGQTYPGQGPPMQGGFNLQGQSPPFNSMMNQMNQQGSFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALEMKMENPTAGGATAMRPMMQPQVNSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQTQAFSPPPNVTASPSMDGVLAGPAMPQAPPQQFPYPSNYGMGQQPDPAFGRVPSPPNAMMSSRMGPSQNPMMQHPQTAPMYQSSEMKGWPSGTLARNSTFPQQQFAHQGNPAAYSMVHMNGSGGPMGQMNMNAMPMAGMPMGPDQKYC", "length": 1411 }, "evidence": [ { "id": "A0A9J7G7M1", "url": "https://omabrowser.org/oma/group/A0A9J7G7M1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9EPU2-1", "protein_name": "Nuclear receptor coactivator 3", "gene_name": "Ncoa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "IIRRCIQRFFSLNDGQSWSQKRHYQEAYIHGHAETPVYRFSLADGTIVSAQTKSKLFRNPVTNDRHGFVSTHFLQREQNGCRPNPILQDKGIRPPAAGCGMSLSPSQSVQMLGSRTYGVADPSNTGQMAGARYGASSSVASLTPGQSLQSPSSYQSNSYGLNMSSPPHGSPGLGPNQQNIMISPRNRGSPKMASHQFSPAAGVHSPMGSSGNTGSHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMNINQPSKASSQDSKSPLGLYCEQNPVESSVCPSNSRDPPVTKENKENSGEASETPRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSNCKDSSISVTSPSGVSSSTSGAVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSTASGGEGSVXQEQLSPXKKENNALLRYLLDRDDPSDVLAKELQPQADGGDSKLSQCSCXTNPSSGQEKDPKIKTEEVSGDLDNLDAILGDLTSSDFYNSPTNGSHPGAKQQMFAGPSSLGLRSPQPVQSVRPPYNRALSLDSPVSVGSVPPVKNVSAFPVLPKQPILAGNPRMMDSQENYGANMGGPNRNVPVNPTSSSGDWGLANSRASRMEPLASSPLGRAGGDYSAALPRPALGSSGPTLPLRSNRLPGARPTLMLQMRAGEVPMGMGVSPYSPAVPSNQPGSWPEGMLSMEQGPHGAQNRPLLRNSLDELLGPPSNPEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVSQGQALESKQDVFQGQEAAVMMDQKAALYGQTYPAQGPPLQGGFHLQGQSPSLNSMMSQISQQGSFPLQGLHPRASMVRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALEMKMESPTGAAVMRPMLQSQQAFFNAQMAAQQKRELMNHHLQQQRMAMMMSQPQPQAFSPPPNVTASPSMDGVLAGSAMPQAPPQQFPYATNYGMGQPPEPAFGRGSSPPSAMMSSRMGPSQNAMVQHPQTAPMYQSSEMKGWPSGNLARNGSFPQQQFAPQANPAAYNMVHMNSSGSHLGQMTMTPMPMSGMPMGPDQKYC", "length": 1082 }, "evidence": [ { "id": "A0A9J7G7M1", "url": "https://omabrowser.org/oma/group/A0A9J7G7M1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y6Q9-1", "protein_name": "Nuclear receptor coactivator 3", "gene_name": "NCOA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"categories": [ "Protein Classification" ] }, { "id": "A0A9J7G9S2", "url": "https://www.orthodb.org/?gene=A0A9J7G9S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278474", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278474", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G7Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7Q4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7Q4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAV2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAV2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTASKRVAKELEDLLKQLPPYLRDLSRDAGNVLVWRMLLLPDQPPYHLKAFHLQIDFPRDYPLRPPTLKFITKIYHPNVREDGQVCLPLISIENWKPSTKTCQVLEALNMLVGRPNPEEPVRLELADLLTQNPEMFKRKAEEFTLQFGMDRPS", "length": 153, "header": "tr|A0A9J7G9S2-1|A0A9J7G9S2_CRIGR Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Cricetulus griseus OX=10029 GN=Ube2l6 PE=3 SV=1 CANONICAL=A0A9J7G9S2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G7Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9S2/entry#A0A9J7G7Q4-1", "sequence": { "sequence": "MTASKRVAKDQPPYHLKAFHLQIDFPRDYPLRPPTLKFITKIYHPNVREDGQVCLPLISIENWKPSTKTCQVLEALNMLVGRPNPEEPVRLELADLLTQNPEMFKRKAEEFTLQFGMDRPS", "length": 121, "header": "tr|A0A9J7G7Q4-1|A0A9J7G9S2_CRIGR Computationally mapped isoform of E2 ubiquitin-conjugating enzyme OS=Cricetulus griseus OX=10029 GN=Ube2l6 PE=3 SV=1 CANONICAL=A0A9J7G9S2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9S2/entry#A0A9J7G9S2-1", "sequence": { "sequence": "MTASKRVAKELEDLLKQLPPYLRDLSRDAGNVLVWRMLLLPDQPPYHLKAFHLQIDFPRDYPLRPPTLKFITKIYHPNVREDGQVCLPLISIENWKPSTKTCQVLEALNMLVGRPNPEEPVRLELADLLTQNPEMFKRKAEEFTLQFGMDRPS", "length": 153, "header": "tr|A0A9J7G9S2-1|A0A9J7G9S2_CRIGR Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Cricetulus griseus OX=10029 GN=Ube2l6 PE=3 SV=1 CANONICAL=A0A9J7G9S2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9S2/entry#A0A9J7KAV2-1", "sequence": { "sequence": "MLLLPDQPPYHLKAFHLQIDFPRDYPLRPPTLKFITKIYHPNVREDGQVCLPLISIENWKPSTKTCQVLEALNMLVGRPNPEEPVRLELADLLTQNPEMFKRKAEEFTLQFGMDRPS", "length": 117, "header": "tr|A0A9J7KAV2-1|A0A9J7KAV2_CRIGR Computationally mapped isoform of E2 ubiquitin-conjugating enzyme OS=Cricetulus griseus OX=10029 GN=Ube2l6 PE=3 SV=1 CANONICAL=A0A9J7G9S2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7Q4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7Q4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756751", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756751", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9S2" } ], "pmid": "" }, { "name": "ubiquitin conjugating enzyme activity", "id": "GO:0061631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061631", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G9S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9S2" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 149, "start_aa": "Thr", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.23", "ec_name": "S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.", "evidence": [ { "id": "2.3.2.23", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.23" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"type": "recommended", "evidence": [ { "id": "A0A9J7G7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R1" } ] }, { "name": "Stkld1", "type": "synonym", "evidence": [ { "id": "XP_027278536", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278536" } ] } ], "protein_names": [ { "name": "Serine/threonine kinase-like domain-containing protein STKLD1", "type": "recommended", "evidence": [ { "id": "A0A9J7G7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R1/entry#names_and_taxonomy" } ] }, { "name": "Serine/threonine kinase-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7G7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R1/entry#names_and_taxonomy" } ] }, { "name": "Sugen kinase 071", "type": "synonym", "evidence": [ { "id": "A0A9J7G7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R1/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine kinase-like domain-containing protein STKLD1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027278536", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278536" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 16% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278536", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278536" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7R1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Stkld1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R1", "locus": {} } ], "crossref": [ { "id": "A0A9J7G7R1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G7R1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00180", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00180", "database": "CDD", "categories": [ "Protein Classification" ] 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"categories": [ "Protein Classification" ] }, { "id": "PTHR24363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24363:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24363:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278536", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278536", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G7R1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7R1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAGSAGWSSALAPAAASTGSARRPALLCRGGSSGCHVGQALKGPRRRRAPPRLPRALTLQTPPATLQGPPADAPPFTRMPRPLHNPKPCPPYILTVQQAPPTALNFLPPTLPPLEIEAPPTVVITVECIDEHHANKALEELMPLLKLQHPNISLYHEMFIMWNNEISSLFLCLVMDYATRGTFQNVIESKRKIRESIDSEWIHTMMSQVMDAIEYLHQQNIIHRNLKPSNIALFSDNHCKLQDLSSEALMTHEAKWNVRAEEDPCQKSWMAPEALKFSFTCKSDIWSLGCIILDMATCSFLNDTEAMYLRKAIRHHPGSLKPILKTMEEKQIPCSEVFCLLMPFMLQIKPSERLVIRDVIRITFMSTSFRNSCVALNMHRQAVPIFITDVLLEGNMANILDVMQTFSNRPEVQLRALNKLLKMTEEELGLPWPTELLEEVLAIMKQHERILDILLNTCNLLLRVLGHALAQDSEAEIPRVDSIISFLMNALRSHPGSERLITTVYNLLTIISSQGMLTEELEERGLFKLIQEHLENFQENRNICLAILSLLWSLLIDATDVDKEPLKTLSTMVTWVLTTYPEDVEIAEAGCAVLWLLSLLGCIKESQFEHVVELFLRSIQLCPRRVLLVNNACRGLASLAKVSELVAFQVVVMEEGSSGLYLLQDMYQLYKDDPEVVENLCMLLAYLASYKEILPELESAGIKDLVRVIRGRFTSSLELISYADTVLQALEAAACSRPQEKQLEPASELEAPKVSFPHQEDPIFQR", "length": 770, "header": "tr|A0A9J7G7R1-1|A0A9J7G7R1_CRIGR Isoform 1 of Serine/threonine kinase-like domain-containing protein STKLD1 OS=Cricetulus griseus OX=10029 GN=Stkld1 PE=4 SV=1 CANONICAL=A0A9J7G7R1-1" }, "isoforms": [ 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G7S3-1", "uniprot_ac": "A0A9J7G7S3", "uniprot_id": "A0A9J7G7S3_CRIGR", "mass": { "chemical_mass": 45340.0, "monoisotopic_mass": 45340.0 }, "refseq": { "ac": "XP_027246562", "name": "UPF0705 protein C11orf49 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246562" }, "gene_names": [ { "name": "CUNH11orf49", "type": "recommended", "evidence": [ { "id": "A0A9J7G7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3" } ] }, { "name": "CUNH11orf49", "type": "synonym", "evidence": [ { "id": "XP_027246562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246562" } ] } ], "protein_names": [ { "name": "Centriolar satellite-associated tubulin polyglutamylase complex regulator 1", "type": "recommended", "evidence": [ { "id": "A0A9J7G7S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3/entry#names_and_taxonomy" } ] }, { "name": "UPF0705 protein C11orf49 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027246562", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246562" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613646.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027246562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246562" } ] }, { "annotation": "Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly. 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and Pathway" ] }, { "id": "A0A9J7G7S3", "url": "https://www.orthodb.org/?gene=A0A9J7G7S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JUB9", "url": "https://www.orthodb.org/?gene=A0A9J7JUB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JVS8", "url": "https://www.orthodb.org/?gene=A0A9J7JVS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34252", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34252", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34252:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34252:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027246562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246562", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G7S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JM52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JM52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JM52-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JM52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUB9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVS8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQANATKDPRITGCGVRGIASQVHDSRMLKGAMATETGCNLDSGSQKAGAWKLPGQRMLSPERLALPDYEYLVRCYFELFSFIRHCAQRHVLTYMEDAVCQLLENKEDIGQYGIARFFTEYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMREYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYQDLLSGKNPNTVIVPTSSSGQHRQRPALGDAGVLDGVEAALFYQRLENLCDRHKYSCPPPALVREILSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDEELERLLVQVPGLVNSIIATSEASCLPSRTPPRVGSPWKPLHRSRKLDAESDGSTEETDESET", "length": 403, "header": "tr|A0A9J7G7S3-1|A0A9J7G7S3_CRIGR Isoform 1 of Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 OS=Cricetulus griseus OX=10029 GN=CUNH11orf49 PE=3 SV=1 CANONICAL=A0A9J7G7S3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G7S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3/entry#A0A9J7G7S3-1", "sequence": { "sequence": "MLQANATKDPRITGCGVRGIASQVHDSRMLKGAMATETGCNLDSGSQKAGAWKLPGQRMLSPERLALPDYEYLVRCYFELFSFIRHCAQRHVLTYMEDAVCQLLENKEDIGQYGIARFFTEYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMREYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYQDLLSGKNPNTVIVPTSSSGQHRQRPALGDAGVLDGVEAALFYQRLENLCDRHKYSCPPPALVREILSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDEELERLLVQVPGLVNSIIATSEASCLPSRTPPRVGSPWKPLHRSRKLDAESDGSTEETDESET", "length": 403, "header": "tr|A0A9J7G7S3-1|A0A9J7G7S3_CRIGR Isoform 1 of Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 OS=Cricetulus griseus OX=10029 GN=CUNH11orf49 PE=3 SV=1 CANONICAL=A0A9J7G7S3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JM52-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3/entry#A0A9J7JM52-1", "sequence": { "sequence": "MLQANATKDPRITGCGVRGIASQVHDSRMLKGAMATETGCNLDSGSQKAGAWKLPGQRMLSPERLALPDYEYLVRCYFELFSFIRHCAQRHVLTYMEDAVCQLLENKEDIGQYGIARFFTEYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMREYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYQDLLSGKNPNTVIVPTSSSGQHRQRPALGDAGVLDGVEAALFYQRLENLCDRHKYSCPPPALVREILSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDEELERLVVRSRLYRTPRQHRGKEPGAFGFQRRDKLEALERVPSALAPTPNPYRWEPRE", "length": 398, "header": "tr|A0A9J7JM52-1|A0A9J7JM52_CRIGR Computationally mapped isoform of Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 OS=Cricetulus griseus OX=10029 GN=CUNH11orf49 PE=3 SV=1 CANONICAL=A0A9J7G7S3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JUB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3/entry#A0A9J7JUB9-1", "sequence": { "sequence": "MLWDAQRHVLTYMEDAVCQLLENKEDIGQYGIARFFTEYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMREYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYQDLLSGKNPNTVIVPTSSSGQHRQRPALGDAGVLDGVEAALFYQRLENLCDRHKYSCPPPALVREILSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDEELERLLVQVPGLVNSIIATSEASCLPSRTPPRVGSPWKPLHRSRKLDAESDGSTEETDESET", "length": 320, "header": "tr|A0A9J7JUB9-1|A0A9J7JUB9_CRIGR Computationally mapped isoform of Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 OS=Cricetulus griseus OX=10029 GN=CUNH11orf49 PE=3 SV=1 CANONICAL=A0A9J7G7S3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3/entry#A0A9J7JVS8-1", "sequence": { "sequence": "MLQANATKDPRITGCGVRGIASQVHDSRMLKGAMATETGCNLDSGSQKAGAWKLPGQRMLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENKEDIGQYGIARFFTEYFNSVCQGTHILFREFSFIQATPHNRASFLRAFWRCFRTVGKNGDLLTMREYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYQDLLSGKNPNTVIVPTSSSGQHRQRPALGDAGVLDGVEAALFYQRLENLCDRHKYSCPPPALVREILSNVQRLTFYGFLVALSKHHGINQALGALPDKGDLMHDPAMDEELERLLVQVPGLVNSIIATSEASCLPSRTPPRVGSPWKPLHRSRKLDAESDGSTEETDESET", "length": 389, "header": "tr|A0A9J7JVS8-1|A0A9J7JVS8_CRIGR Computationally mapped isoform of Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 OS=Cricetulus griseus OX=10029 GN=CUNH11orf49 PE=3 SV=1 CANONICAL=A0A9J7G7S3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 248, "start_aa": "Thr", "end_pos": 248, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr248", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755821", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755821", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7S3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 248 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7T3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7T3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769581", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769581", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7T3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7T3" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7T3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7T3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7T3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7T3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G7T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7T3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G8B2-1", "uniprot_ac": "A0A9J7G8B2", "uniprot_id": "A0A9J7G8B2_CRIGR", "mass": { "chemical_mass": 79559.0, "monoisotopic_mass": 79559.0 }, "refseq": { "ac": "XP_027279307", "name": "myb-related protein B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279307" }, "gene_names": [ { "name": "Mybl2", "type": "recommended", "evidence": [ { "id": "A0A9J7G8B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B2" } ] }, { "name": "Mybl2", "type": "synonym", "evidence": [ { "id": "XP_027279307", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279307" } ] } ], "protein_names": [ { "name": "Myb-related protein B", "type": "recommended", "evidence": [ { "id": "A0A9J7G8B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B2/entry#names_and_taxonomy" } ] }, { "name": "Myb-like protein 2", "type": "synonym", "evidence": [ { "id": "A0A9J7G8B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B2/entry#names_and_taxonomy" } ] }, { "name": "myb-related protein B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027279307", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279307" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279307" } ] }, { "annotation": "Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7T5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7T5#function" }, { "database": "UniProtKB", "id": "ARBA00057435", "url": "https://www.uniprot.org/uniprotkb/ARBA00057435#function" }, { "database": "UniProtKB", "id": "A0A9J7G8B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mybl2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B2", "locus": {} } ], "crossref": [ { "id": "A0A9J7G8B2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G8B2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773251", "url": "https://www.ncbi.nlm.nih.gov/gene/100773251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773251", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G8B2", "url": "https://www.orthodb.org/?gene=A0A9J7G8B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45614:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45614:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09316", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09316", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279307", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G7T5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7T5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8B2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRTRCCLHSEELDELHYQDTDSDLLEPRDNKCKVKWTHEEDEQLRALVRQFGQQDWKFLASHFPNRTDQQCQYRWLRVLNPDLVKGPWTKEEDQKVIELVKKYGTKQWTLIAKHLKGRLGKQCRERWHNHLNPEVKKSCWTEEEDRIICEAHKVLGNRWAEIAKMLPGRTDNAVKNHWNSTIKRKVDTGGFPSESRDCKPVYLLLELEDKDRHQSAQPLEGQGSLMTGWPLAPSTVKEEENSEEEAAAAAISAAKEPEPEPEPEPVPTDLGEVHTPESLESLKREYQEDSSPETSLPYKWVVEAANLLIPAVGSSLSEALDLIESDPDAWCDLSKFDLPEEPSAEGSVNSSPVQPQTSQQQQQAQSSHQSATPGPSMTEYRLDGHTISDLSRSSRGELIPISPSTEVGGSGIGTPPSVLKRQKKRRVALSPVTENSASLSFLDSCNSLTPKSTPVKTLPFSPSQFLNFWNKQDTLELESPSLTSTPVCSQKVVVTTPLHRDKTPLHQKYPSFVTPDQKYSMDNTPHTPTPFKNALEKYGPLKPLPQTPHLEEDLKEVLRSEAGIELIVEDDVRPEKQKRKPGLRRSPVKKVRKSLALDIVDEDGKLMSSLPKALSLPTSVPSSSSSFTLPGSKEDNSLLNQGFLQAKPEKVVATQKSRGHIPAPAPMTSAWKMVACGGTKDQLFMQEKARQLLGRLKPSHTSRTLILS", "length": 710, "header": "tr|A0A9J7G8B2-1|A0A9J7G8B2_CRIGR Isoform 1 of Myb-related protein B OS=Cricetulus griseus OX=10029 GN=Mybl2 PE=4 SV=1 CANONICAL=A0A9J7G8B2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G7T5-1", "url": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278434" } ] }, { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7X0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X0#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7X0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100754899", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X0", "locus": {} } ], "crossref": [ { "id": "A0A9J7G7X0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G7X0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15414", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15414", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754899", "url": "https://www.ncbi.nlm.nih.gov/gene/100754899", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754899", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754899", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G7X0", "url": "https://www.orthodb.org/?gene=A0A9J7G7X0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278434", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G7X0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEKNQTAVTEFLFLGISDKLYQKIVLFIIFFLVYLVSLGGNLGMITLIWGDSRLHTPMYFFLSHLSFVDVCSSSSIAPRMLCDIFAENKIISFVGCAAQMWFFGLFVTTDCFLLAVMAYDRYTAICKPLLYTLIMSQSVCVQFVIGPYVLAAINITTHTTLTFCLPFCGPNTINHFFCDVSPLLSLACADTWINKVVLSVLAGMIGVTSGLIILVSYICILVAILKIKTADGRQKAFSTCSSHLAAVSILYGTLFFIYVRPNAGSSLDINKVISLFYTVVIPMLNPLIYSLRNKEVKDAFSRTLERKHFLIGA", "length": 314, "header": "tr|A0A9J7G7X0-1|A0A9J7G7X0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100754899 PE=3 SV=1 CANONICAL=A0A9J7G7X0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G7X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X0/entry#A0A9J7G7X0-1", "sequence": { "sequence": "MEEKNQTAVTEFLFLGISDKLYQKIVLFIIFFLVYLVSLGGNLGMITLIWGDSRLHTPMYFFLSHLSFVDVCSSSSIAPRMLCDIFAENKIISFVGCAAQMWFFGLFVTTDCFLLAVMAYDRYTAICKPLLYTLIMSQSVCVQFVIGPYVLAAINITTHTTLTFCLPFCGPNTINHFFCDVSPLLSLACADTWINKVVLSVLAGMIGVTSGLIILVSYICILVAILKIKTADGRQKAFSTCSSHLAAVSILYGTLFFIYVRPNAGSSLDINKVISLFYTVVIPMLNPLIYSLRNKEVKDAFSRTLERKHFLIGA", "length": 314, "header": "tr|A0A9J7G7X0-1|A0A9J7G7X0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100754899 PE=3 SV=1 CANONICAL=A0A9J7G7X0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7X0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"UniProtKB", "id": "A0A9J7G7X0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7X0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G7X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X0" }, { "id": "PS50262", "database": "PROSITE", "url": 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 10% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027279408.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279408", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279408" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G7X6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753242", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X6", "locus": {} } ], "crossref": [ { "id": "A0A9J7G7X6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G7X6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753242", "url": "https://www.ncbi.nlm.nih.gov/gene/100753242", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753242", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753242", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G7X6", "url": "https://www.orthodb.org/?gene=A0A9J7G7X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279408", "url": 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"MSSRHCFIRVVRTPALVLTPVTERSIHQTQPLLKQFSEGLRSNKVHNRVRSGVHSGRTQIGTGQASALPRSPPGAPSGCHKFSGDLKPARDSDGEVVTLRLRKILPLPTFHGFPGLRPAPVSVPFLQWRSGAVGVALRRGGACELSDFLAFEDVAVKFSQEEWILLDPSQKKLYRDVMLETCINLTSLGIKWEDKNIEEQYKHSWRYLRSYMVDAINEHKEGGQFQETYIWIRNLHSIANISTGIKLFECGVCEKVFTCHSSFKEHIMSHLGDKSSEHKYGSFGIQQQSHSGEKFCKKCGMAFICPCSFSVDGRTNTEDKCYECMPCGKALSSSSSLQRVHTGERPYECEHCGKFFRHQSSFRLHKLTHIGGKPYECKQCGKAFRCYNYLQLHEIFHIEENPLECKQCGKTLCSPSSLRFHERIHNAEKLYICKQCGKAFKCQSYLRMHERSHNGEKCYDCKQCGKAFRSHCSLQRHKVAHPGEKPYTCNLCGKSFTYPYLLQTHGRFHTGEKPYKCKLCNKAFLCSPFLQTHKRTHTWGKPYKCKQCGETFRSHSFLRSHTRAHTVEKPYKCKICSKAFLCFPYLQRHERAHTEEKLFECKQCSKIFRDWSTFQVHERSHIVEKPYKCKKCSKAFFYPSSLERHEKIHKGEKHYACKYACKQCGQSFIFPCLLERHLRSHTTEKPYECKHCGKAFRSLTYIHIHKRTHTEERLYTCKQCDKSLSCPSALQFHELTHTREKPHACLQFDKTIRKLSYFQVPEKALTEEKTYTCQQCGKILDCASSLQLHERIHTGEKSHECKQCGKTFTVLSSLRVHEMSHRHEKPYECKQLGQVFSLSNIHEIKKAEGNPCECKQCGKTFVSRYLLQMHERSHSAEKRYECKVCGKTFIYPSFLQRHERTHTGEKPYECKQCGKAFRVQSSLRLHERTHSEEKPYECQHCGKAFWRFPSLQVHERIHTGEKPFECKQCDKTFRCHSSLQRHERTHSQEKPYECEQCGKAFRCHRSFQRHGKTHAGEKAT", "length": 1020, "header": "tr|A0A9J7G7X6-1|A0A9J7G7X6_CRIGR Isoform 1 of Zinc finger protein 709 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100753242 PE=3 SV=1 CANONICAL=A0A9J7G7X6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G7X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7X6/entry#A0A9J7G7X6-1", "sequence": { "sequence": 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"categories": [ "Protein" ] }, { "id": "A0A9J7GB33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB33-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB36", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB36-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H183", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H183", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H183-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H183-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H282", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H282", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H282-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H282-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5A4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JWP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JWP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISAMDGVPFMISEKFSCIPESMQPFDLLGITIKSLAEIEKEYEYSFRTEQSAAARLPPSPTRCQQIPQS", "length": 316, "header": "tr|A0A9J7G8L4-1|A0A9J7G8L4_CRIGR Isoform 1 of Multivesicular body subunit 12B OS=Cricetulus griseus OX=10029 GN=LOC113836527 PE=3 SV=1 CANONICAL=A0A9J7G8L4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G837-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4/entry#A0A9J7G837-1", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISESDGDGLLNVRENTSSLTPIQKTRQEKLSAAVQPAPLEARMPTRIIT", "length": 296, "header": "tr|A0A9J7G837-1|A0A9J7G8L4_CRIGR Computationally mapped isoform of Multivesicular body subunit 12B OS=Cricetulus griseus OX=10029 GN=LOC113836527 PE=3 SV=1 CANONICAL=A0A9J7G8L4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4/entry#A0A9J7G8L4-1", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISAMDGVPFMISEKFSCIPESMQPFDLLGITIKSLAEIEKEYEYSFRTEQSAAARLPPSPTRCQQIPQS", "length": 316, "header": "tr|A0A9J7G8L4-1|A0A9J7G8L4_CRIGR Isoform 1 of Multivesicular body subunit 12B OS=Cricetulus griseus OX=10029 GN=LOC113836527 PE=3 SV=1 CANONICAL=A0A9J7G8L4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB33-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4/entry#A0A9J7GB33-1", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISGGEPT", "length": 254, "header": "tr|A0A9J7GB33-1|A0A9J7GB33_CRIGR Computationally mapped isoform of Multivesicular body subunit 12B OS=Cricetulus griseus OX=10029 GN=LOC113836527 PE=3 SV=1 CANONICAL=A0A9J7G8L4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB36-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4/entry#A0A9J7GB36-1", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISGNLK", "length": 253, "header": "tr|A0A9J7GB36-1|A0A9J7GB36_CRIGR Computationally mapped isoform of Multivesicular body subunit 12B OS=Cricetulus griseus OX=10029 GN=LOC113836527 PE=3 SV=1 CANONICAL=A0A9J7G8L4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4/entry#A0A9J7GCN8-1", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISAHSWAELPEQQMTVVTAASLSLAPGFTTSCEDQSRAMMWESWPW", "length": 293, "header": "tr|A0A9J7GCN8-1|A0A9J7GCN8_CRIGR Computationally mapped isoform of Multivesicular body subunit 12B OS=Cricetulus griseus OX=10029 GN=LOC113836527 PE=3 SV=1 CANONICAL=A0A9J7G8L4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H183-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4/entry#A0A9J7H183-1", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISGCFQVDKVKIPSREGSRSCGARVPPCWGRGLDTSLPYHLDTREPRPGLWEGLAPSFA", "length": 306, "header": "tr|A0A9J7H183-1|A0A9J7H183_CRIGR Computationally mapped isoform of Multivesicular body subunit 12B OS=Cricetulus griseus OX=10029 GN=LOC113836527 PE=3 SV=1 CANONICAL=A0A9J7G8L4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H282-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4/entry#A0A9J7H282-1", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISASVSRGPPFMEARARKSGQLQMLYSGHLWRIPSL", "length": 283, "header": "tr|A0A9J7H282-1|A0A9J7H282_CRIGR Computationally mapped isoform of Multivesicular body subunit 12B OS=Cricetulus griseus OX=10029 GN=LOC113836527 PE=3 SV=1 CANONICAL=A0A9J7G8L4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4/entry#A0A9J7H5A4-1", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISVCADHRPVLIAEILGKIGISHGIKDIGLVWGDGSVSKVFILQAMRT", "length": 295, "header": "tr|A0A9J7H5A4-1|A0A9J7H5A4_CRIGR Computationally mapped isoform of Multivesicular body subunit 12B OS=Cricetulus griseus OX=10029 GN=LOC113836527 PE=3 SV=1 CANONICAL=A0A9J7G8L4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JWP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4/entry#A0A9J7JWP8-1", "sequence": { "sequence": "MRSCFCVRRSRDPPPPQPPPQRGTDQATMPEVKELSEALPETPMDPITGVGVVASRNRAPTGYDVVAQTADGVDADLWKDGLFKSKVTRYLCFTRSFSKENSHLGNVLVDMKLIDVKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDSTEAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAPNLPRHISLTLPATFRGRNNTSTDYEYQLSNLYAISGNTPAGSGEPQV", "length": 261, "header": "tr|A0A9J7JWP8-1|A0A9J7JWP8_CRIGR Computationally mapped isoform of Multivesicular body subunit 12B OS=Cricetulus griseus OX=10029 GN=LOC113836527 PE=3 SV=1 CANONICAL=A0A9J7G8L4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 211, "start_aa": "Thr", "end_pos": 211, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr211", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G837", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G837" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G837", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G837" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113836527", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836527", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4" } ], "pmid": "" }, { "name": "regulation of epidermal growth factor receptor signaling pathway", "id": "GO:0042058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042058", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4" } ], "pmid": "" }, { "name": "viral budding", "id": "GO:0046755", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046755", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4" } ], "pmid": "" }, { "name": "virus maturation", "id": "GO:0019075", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019075", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4" } ], "pmid": "" }, { "name": "ESCRT I complex", "id": "GO:0000813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8L4" }, { "id": "PS51498", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51498" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MABP", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 190, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027275428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027275428" } ] }, { "annotation": "Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers and promote formation of the H3K27me3 mark by the PRC2/EED-EZH2 complex. 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277305" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G887" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zcchc3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G887", "locus": {} } ], "crossref": [ { "id": "A0A9J7G887", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G887", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751149", "url": "https://www.ncbi.nlm.nih.gov/gene/100751149", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", 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Classification" ] }, { "id": "PTHR22639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22639:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22639:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23058", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23058", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277305", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277305", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G887", "url": 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"isoform_ac": "A0A9J7G887-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G887/entry#A0A9J7G887-1", "sequence": { "sequence": "MQLRPACETPKPRERGRGPSLQGEGGLGPRRLAGARAVSGQHEASRRAEARSVGFQSGAGSRPRSRQPATLIPSRRAPWASRAAGASGGRWERGNMATGGGAEGDLQRGRGPLPLPARPAARAEDAEGVREKMGWAQVVKNLAEKKGDFREPRRRDEAGSAASGGLGSPAGLAAPNPGDFPPAGRGDPKGRGREPAGEAADACRRKGAGDESPRKKAEVAAAAVAVATPARPGATEDAAERPLQDEPPAAGGSGKGRFLVRICFQGDESACPTRDFVVGALILRSIGMDPDDIYAVIQIPGSREFDVSFRSADKLALFLRVYEEKRELEDCWENFVVLGRSKSSLKTLFILFRNETVDVEDIVTWLKRHCDVLAVPVKVTDRFGIWTGEYKCEIELRQGEGGVRHLPGAFFLGAERGYSWYKGQPKTCFKCGSRTHMSGTCTQDRCFRCGEEGHLSPYCRKVIVCNLCGKRGHAFAQCPKAVHNSVAAQLTGVAGH", "length": 496, "header": "tr|A0A9J7G887-1|A0A9J7G887_CRIGR Isoform 1 of Zinc finger CCHC domain-containing protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Zcchc3 PE=4 SV=1 CANONICAL=A0A9J7G887-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G887" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G887" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751149", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751149", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cellular response to exogenous dsRNA", "id": "GO:0071360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071360", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G887" } ], "pmid": "" }, { "name": "defense response to virus", "id": "GO:0051607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G887" } ], "pmid": "" }, { "name": "positive regulation of RIG-I signaling pathway", "id": "GO:1900246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900246", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G887" } ], "pmid": "" }, { "name": "activation of innate immune response", "id": "GO:0002218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002218", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G887" } ], "pmid": "" }, { "name": "positive regulation of type I interferon production", "id": "GO:0032481", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032481", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G887", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G887" } ], "pmid": "" }, { "name": "detection of virus", "id": "GO:0009597", "url": 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279268", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279268" } ] }, { "annotation": "Major component of the extracellular matrix of cartilage.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G892", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G892#function" }, { "database": "UniProtKB", "id": "ARBA00055899", "url": "https://www.uniprot.org/uniprotkb/ARBA00055899#function" }, { "database": "UniProtKB", "id": "A0A9J7G8P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", 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"Protein" ] }, { "id": "A0A9J7K908", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K908", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K908-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K908-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGLFWPLSLLLLSLQPWEIQLQSAGPRCYTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAISAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPPEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAEWGHGCQHQCVNAPGTFYCTCNSGYKLAPDNKNCLAMDLCAEGTHGCEHLCVNSLDSYFCRCRAGFALQQDQKSCRAIDYCSFGNHSCQHECVNTLEGPQCICREGHDLLPDGRSCRVRDFCNGVDHGCEFQCVSEGLSFRCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRIGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYAPDFSTMTHLLENLKGSICPVLLAEEGISAGTELRSPCECESLVEFQGRTLGALESLTRNLAQLTERLEELENQLTSRK", "length": 627, "header": "tr|A0A9J7G8P3-1|A0A9J7G8P3_CRIGR Isoform 1 of Matrilin-4 OS=Cricetulus griseus OX=10029 GN=Matn4 PE=4 SV=1 CANONICAL=A0A9J7G8P3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G892-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3/entry#A0A9J7G892-1", "sequence": { "sequence": "MRGLFWPLSLLLLSLQPWEIQLQSAGPRCYTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAISAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPPEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAEWGHGCQHQCVNAPGTFYCTCNSGYKLAPDNKNCLAMDLCAEGTHGCEHLCVNSLDSYFCRCRAGFALQQDQKSCRAIDYCSFGNHSCQHECVNTLEGPQCICREGHDLLPDGRSCRVRDFCNGVDHGCEFQCVSEGLSFRCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRIGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYAPDFSTMTHLLENLKGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTRNLAQLTERLEELENQLTSRK", "length": 623, "header": "tr|A0A9J7G892-1|A0A9J7G8P3_CRIGR Computationally mapped isoform of Matrilin-4 OS=Cricetulus griseus OX=10029 GN=Matn4 PE=4 SV=1 CANONICAL=A0A9J7G8P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3/entry#A0A9J7G8P3-1", "sequence": { "sequence": "MRGLFWPLSLLLLSLQPWEIQLQSAGPRCYTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAISAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPPEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAEWGHGCQHQCVNAPGTFYCTCNSGYKLAPDNKNCLAMDLCAEGTHGCEHLCVNSLDSYFCRCRAGFALQQDQKSCRAIDYCSFGNHSCQHECVNTLEGPQCICREGHDLLPDGRSCRVRDFCNGVDHGCEFQCVSEGLSFRCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRIGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYAPDFSTMTHLLENLKGSICPVLLAEEGISAGTELRSPCECESLVEFQGRTLGALESLTRNLAQLTERLEELENQLTSRK", "length": 627, "header": "tr|A0A9J7G8P3-1|A0A9J7G8P3_CRIGR Isoform 1 of Matrilin-4 OS=Cricetulus griseus OX=10029 GN=Matn4 PE=4 SV=1 CANONICAL=A0A9J7G8P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3/entry#A0A9J7JZM8-1", "sequence": { "sequence": "MRGLFWPLSLLLLSLQPWEIQLQSAGPRCYTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAISAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPPEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAEWGHGCQHQCVNAPGTFYCTCNSGYKLAPDNKNCLAMDLCAEGTHGCEHLCVNSLDSYFCRCRAGFALQQDQKSCRAIDYCSFGNHSCQHECVNTLEGPQCICREGHDLLPDGRSCRVRDFCNGVDHGCEFQCVSEGLSFRCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRIGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYAPDFSTMTHLLENLKGSICPVLLAEEGISAGTELRSPCECESLVEFQGRTLGALESLTRNPDRAPGGTGEPAD", "length": 621, "header": "tr|A0A9J7JZM8-1|A0A9J7JZM8_CRIGR Computationally mapped isoform of Matrilin-4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Matn4 PE=4 SV=1 CANONICAL=A0A9J7G8P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K908-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3/entry#A0A9J7K908-1", "sequence": { "sequence": "MRGLFWPLSLLLLSLQPWEIQLQSAGPRCYTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAISAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPPEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAEWGHGCQHQCVNAPGTFYCTCNSGYKLAPDNKNCLAMDLCAEGTHGCEHLCVNSLDSYFCRCRAGFALQQDQKSCRAIDYCSFGNHSCQHECVNTLEGPQCICREGHDLLPDGRSCRVRDFCNGVDHGCEFQCVSEGLSFRCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRIGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYAPDFSTMTHLLENLKGSICPDAGIEA", "length": 574, "header": "tr|A0A9J7K908-1|A0A9J7K908_CRIGR Computationally mapped isoform of Matrilin-4 isoform X5 OS=Cricetulus griseus OX=10029 GN=Matn4 PE=4 SV=1 CANONICAL=A0A9J7G8P3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3/entry#A0A9J7KAH0-1", "sequence": { "sequence": "MRGLFWPLSLLLLSLQPWEIQLQSAGPRCYTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAISAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPPEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAEWGHGCQHQCVNAPGTFYCTCNSGYKLAPDNKNCLAMDLCAEGTHGCEHLCVNSLDSYFCRCRAGFALQQDQKSCRAIDYCSFGNHSCQHECVNTLEGPQCICREGHDLLPDGRSCRVRDFCNGVDHGCEFQCVSEGLSFRCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRIGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYAPDFSTMTHLLENLKGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTRNPDRAPGGTGEPAD", "length": 617, "header": "tr|A0A9J7KAH0-1|A0A9J7KAH0_CRIGR Computationally mapped isoform of Matrilin-4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Matn4 PE=4 SV=1 CANONICAL=A0A9J7G8P3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G892", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G892" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G892", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G892" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758854", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758854", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3" } ], "pmid": "" }, { "name": "matrilin complex", "id": "GO:0120216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120216", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "response to axon injury", "id": "GO:0048678", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048678", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G8P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8P3" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 214, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 306, "end_pos": 308 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G8B8-1", "uniprot_ac": "A0A9J7G8B8", "uniprot_id": "A0A9J7G8B8_CRIGR", "mass": { "chemical_mass": 29733.0, "monoisotopic_mass": 29733.0 }, "refseq": { "ac": "XP_027279051", "name": "seminal vesicle secretory protein 3A-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279051" }, "gene_names": [ { "name": "LOC100764067", "type": "recommended", "evidence": [ { "id": "A0A9J7G8B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B8" } ] }, { "name": "LOC100764067", "type": "synonym", "evidence": [ { "id": "XP_027279051", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279051" } ] } ], "protein_names": [ { "name": "Seminal vesicle secretory protein 3A-like", "type": "synonym", "evidence": [ { "id": "A0A9J7G8B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B8/entry#names_and_taxonomy" } ] }, { "name": "seminal vesicle secretory protein 3A-like", "type": "synonym", "evidence": [ { "id": "XP_027279051", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279051" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279051" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8B8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764067", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B8", "locus": {} } ], "crossref": [ { "id": "A0A9J7G8B8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G8B8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100764067", "url": "https://www.ncbi.nlm.nih.gov/gene/100764067", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764067", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764067", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G8B8", "url": "https://www.orthodb.org/?gene=A0A9J7G8B8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10547", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10547", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10547:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10547:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279051", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G8B8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSIFFSLSLLLLLGKQAAGIGTYGGPKGHFLVRTPPVVFIQKGHFHYGPSEEREAASEESVFTQTKQHAYSQDADAEVRETQSSQEQTDLNEDIDCDEEDEISQQKSQLQSQSQIKSQAQLRSQEGQLKSQTGQRKTLGQVIAQVKLKSHSAPLKPYQAPLTLQKVSAQQIKGKEYALDEDLARVHQQDKKVHKLKRNLGWARKTAENLPHLRQHSQGYDGYVMQFQEQLQGGIHHTKSLHQAQGMCYCPKGGLFLHQEVFAE", "length": 264, "header": "tr|A0A9J7G8B8-1|A0A9J7G8B8_CRIGR Isoform 1 of Seminal vesicle secretory protein 3A-like OS=Cricetulus griseus OX=10029 GN=LOC100764067 PE=3 SV=1 CANONICAL=A0A9J7G8B8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G8B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B8/entry#A0A9J7G8B8-1", "sequence": { "sequence": "MKSIFFSLSLLLLLGKQAAGIGTYGGPKGHFLVRTPPVVFIQKGHFHYGPSEEREAASEESVFTQTKQHAYSQDADAEVRETQSSQEQTDLNEDIDCDEEDEISQQKSQLQSQSQIKSQAQLRSQEGQLKSQTGQRKTLGQVIAQVKLKSHSAPLKPYQAPLTLQKVSAQQIKGKEYALDEDLARVHQQDKKVHKLKRNLGWARKTAENLPHLRQHSQGYDGYVMQFQEQLQGGIHHTKSLHQAQGMCYCPKGGLFLHQEVFAE", "length": 264, "header": "tr|A0A9J7G8B8-1|A0A9J7G8B8_CRIGR Isoform 1 of Seminal vesicle secretory protein 3A-like OS=Cricetulus griseus OX=10029 GN=LOC100764067 PE=3 SV=1 CANONICAL=A0A9J7G8B8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"UniProtKB", "id": "A0A9J7G8B8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B8" } ], "pmid": "" }, { "name": "coagulation", "id": "GO:0050817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050817", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8B8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8B8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8B8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], 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"protein_names": [ { "name": "Noelin isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7G8E8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E8/entry#names_and_taxonomy" } ] }, { "name": "noelin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027278843", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278843" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278843", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278843" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8E8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Olfm1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E8", "locus": {} } ], "crossref": [ { "id": "A0A9J7G8E8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G8E8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100752985", "url": "https://www.ncbi.nlm.nih.gov/gene/100752985", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752985", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752985", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G8E8", "url": "https://www.orthodb.org/?gene=A0A9J7G8E8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12308", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12308", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278843", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278843", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G8D9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8E8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARAHRVAETGGRRRAEGAGDAAGRPCPPWCPPPETAWGAGASAGAARAQEATRGAMSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL", "length": 541, "header": "tr|A0A9J7G8E8-1|A0A9J7G8E8_CRIGR Isoform 1 of Noelin isoform X2 OS=Cricetulus griseus OX=10029 GN=Olfm1 PE=4 SV=1 CANONICAL=A0A9J7G8E8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G8D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E8/entry#A0A9J7G8D9-1", "sequence": { "sequence": "MARAHRVAETGGRRRAEGAGDAAGRPCPPWCPPPETAWGAGASAGAARAQEATRGAMSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKG", "length": 209, "header": "tr|A0A9J7G8D9-1|A0A9J7G8D9_CRIGR Computationally mapped isoform of Noelin isoform X4 OS=Cricetulus griseus OX=10029 GN=Olfm1 PE=4 SV=1 CANONICAL=A0A9J7G8E8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E8/entry#A0A9J7G8E8-1", "sequence": { "sequence": "MARAHRVAETGGRRRAEGAGDAAGRPCPPWCPPPETAWGAGASAGAARAQEATRGAMSVPLLKIGVVLSTMAMITNWMSQTLPSLVGLNTTRLSAASGGTLDRSTGVLPTNPEESWQVYSSAQDSEGRCICTVVAPQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQVEESHKQHLARQFKAIKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNELQEEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGSRFGSWMTDPLAPEGDNRVWYMDGYHNNRFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSIYFNKFQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDENGLWAVYATNQNAGNIVISKLDPVSLQILQTWNTSYPKRSAGEAFIICGTLYVTNGYSGGTKVHYAYQTNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQTLYNVTLFHVIRSDEL", "length": 541, "header": "tr|A0A9J7G8E8-1|A0A9J7G8E8_CRIGR Isoform 1 of Noelin isoform X2 OS=Cricetulus griseus OX=10029 GN=Olfm1 PE=4 SV=1 CANONICAL=A0A9J7G8E8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8E8/entry#A0A9J7JSW4-1", "sequence": { "sequence": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G8I7-1", "uniprot_ac": "A0A9J7G8I7", "uniprot_id": "A0A9J7G8I7_CRIGR", "mass": { "chemical_mass": 95513.0, "monoisotopic_mass": 95513.0 }, "refseq": { "ac": "XP_027278918", "name": "outer dense fiber protein 2 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278918" }, "gene_names": [ { "name": "Odf2", "type": "recommended", "evidence": [ { "id": "A0A9J7G8I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7" } ] }, { "name": "Odf2", "type": "synonym", "evidence": [ { "id": "XP_027278918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278918" } ] } ], "protein_names": [ { "name": "Outer dense fiber protein 2", "type": "recommended", "evidence": [ { "id": "A0A9J7G8I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7/entry#names_and_taxonomy" } ] }, { "name": "Cenexin", "type": "synonym", "evidence": [ { "id": "A0A9J7G8I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7/entry#names_and_taxonomy" } ] }, { "name": "Outer dense fiber of sperm tails protein 2", "type": "synonym", "evidence": [ { "id": "A0A9J7G8I7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7/entry#names_and_taxonomy" } ] }, { "name": "outer dense fiber protein 2 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027278918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278918" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278918" } ] }, { "annotation": "Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8H8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8H8#function" }, { "database": "UniProtKB", "id": "ARBA00037601", "url": "https://www.uniprot.org/uniprotkb/ARBA00037601#function" }, { "database": "UniProtKB", "id": "A0A9J7G8I7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7#function" }, { "database": "UniProtKB", "id": "A0A9J7GYL0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYL0#function" }, { "database": "UniProtKB", "id": "A0A9J7JMG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMG6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8I7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Odf2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7", "locus": {} } ], "crossref": [ { "id": "100764598", "url": "https://www.ncbi.nlm.nih.gov/gene/100764598", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764598", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764598", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G8I7", "url": "https://www.orthodb.org/?gene=A0A9J7G8I7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23162", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23162", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23162:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23162:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27578", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27578", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278918", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G8H8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8I7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYL0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMG6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAANSQKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEKDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKQQASQKENKQLSLKVDELERKLEATSAQNVEFLQVIAKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDGPYTSSYLTSSPIRSRSPPA", "length": 826, "header": "tr|A0A9J7G8I7-1|A0A9J7G8I7_CRIGR Isoform 1 of Outer dense fiber protein 2 OS=Cricetulus griseus OX=10029 GN=Odf2 PE=3 SV=1 CANONICAL=A0A9J7G8I7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G8H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7/entry#A0A9J7G8H8-1", "sequence": { "sequence": "MSASSSGGSPRFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKNPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKQQASQKENKQLSLKVDELERKLEATSAQNVEFLQVIAKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDGPYTSSYLTSSPIRSRSPPA", "length": 811, "header": "tr|A0A9J7G8H8-1|A0A9J7G8I7_CRIGR Computationally mapped isoform of Outer dense fiber protein 2 OS=Cricetulus griseus OX=10029 GN=Odf2 PE=3 SV=1 CANONICAL=A0A9J7G8I7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7/entry#A0A9J7G8I7-1", "sequence": { "sequence": "MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAANSQKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEKDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKQQASQKENKQLSLKVDELERKLEATSAQNVEFLQVIAKREEAIHQAQLRLEEKTRECGSLARQLESAIEDARRQVEQTKEQALSKERAAQSKILDLETQLSRTKTELGQLRRTRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDGPYTSSYLTSSPIRSRSPPA", "length": 826, "header": "tr|A0A9J7G8I7-1|A0A9J7G8I7_CRIGR Isoform 1 of Outer dense fiber protein 2 OS=Cricetulus griseus OX=10029 GN=Odf2 PE=3 SV=1 CANONICAL=A0A9J7G8I7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7/entry#A0A9J7GYL0-1", "sequence": { "sequence": "MKDRSSTPPLHVHVDENTPVHVHIKKLPKPSAANSQKSHKRGMKGDTVNVRRSVRVKTKNPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRVRDWQKGSHELARAGSRLPR", "length": 633, "header": "tr|A0A9J7GYL0-1|A0A9J7GYL0_CRIGR Computationally mapped isoform of Outer dense fiber protein 2 OS=Cricetulus griseus OX=10029 GN=Odf2 PE=3 SV=1 CANONICAL=A0A9J7G8I7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JMG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7/entry#A0A9J7JMG6-1", "sequence": { "sequence": "MGELPTGCRKRRRKRGGAAAGAGLHPPRRLHGTTLASDFNDFIRRRFWAQPCRSWFPSCGKNGVTSLTQKKVLRTPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARHVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERIKEEKDFTMLQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRCKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKETLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKDKGDLELEIIVLNDRVTDLVNQQQSLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRVRDWQKGSHELARAGSRLPR", "length": 701, "header": "tr|A0A9J7JMG6-1|A0A9J7JMG6_CRIGR Computationally mapped isoform of Outer dense fiber protein 2 OS=Cricetulus griseus OX=10029 GN=Odf2 PE=3 SV=1 CANONICAL=A0A9J7G8I7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8H8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8H8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8H8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8H8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764598", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764598", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8I7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8I7" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8I7", "url": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027279896.1. 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"A0A9J7G8N0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8N0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8N0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8N0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ], "pmid": "" }, { "name": "negative regulation of glycogen biosynthetic process", 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"ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP 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"id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] } ] }, { "uniprot_ac": "A0A9J7G969", "gene_name": "LOC100754771", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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"https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] } ] }, { "uniprot_ac": "A0A9J7GRB5", "gene_name": "LOC113838167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] } ] }, { "uniprot_ac": "A0A9J7GRC1", "gene_name": "LOC100764806", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] } ] }, { "uniprot_ac": "A0A9J7GT89", "gene_name": "LOC100774420", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] } ] }, { "uniprot_ac": "A0A9J7GY39", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] } ] }, { "uniprot_ac": "A0A9J7GZH5", "gene_name": "Ripk4", "activity": [ { "ec_number": "2.7.11.1", "activity": 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"ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "A0A9J7H3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E2" } ] } ] }, { "uniprot_ac": "A0A9J7H3L8", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] } ] }, { "uniprot_ac": "G3IN30", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] } ] }, { "uniprot_ac": "O55076", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] } ] }, { "uniprot_ac": "P25321", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P25321", "database": "UniProtKB", 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279313" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sgk2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4", "locus": {} } ], "crossref": [ { "id": "A0A9J7G8N4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G8N4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05603", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05603", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"MASSPVGVPRPQPSRANGNINLGPSANPNARPTDFEFLKVIGKGNYGKVLLARRKSDGAFYAVKVLQKKSIIKSKENHIMAERNVLLKNVQHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACDLLQGLLHKDQRQRLGSKADFLDIKDHVFFSPINWDDLYHKRLTPPFNPNVEGPADLKHFDPEFTQEAVSKSIGCTPDTMASSSGTSSAFLGFSYAQDEDDILDS", "length": 366, "header": "tr|A0A9J7GDE7-1|A0A9J7GDE7_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Sgk2 PE=3 SV=1 CANONICAL=A0A9J7G8N4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772733", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772733", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", 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"A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": 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[ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": 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H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": 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} ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] } ] }, { "uniprot_ac": "A0A9J7G969", "gene_name": "LOC100754771", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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= O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] } ] }, { "uniprot_ac": "G3IN30", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] } ] }, { "uniprot_ac": "O55076", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = 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"MATVSPPTKCQTSVTFEDVAVTFTDEEWRHLVPVQRALYKAVMLETYETIISLGIPVPRSDMILLLKRDKPWTQDLLGSKEKEWPESISLDQETKPESLAASEGTLGESHRQQSPLCPKPKVQTLAGGSEPEKERLEAETCKKPLSLDKSLKGRSAPSKKILTKRQDQECRECGKTFFDHWSLIRHHRTHTGEKPYDCPECGKAFSQRSTLSRHLISHTGEGPYKCSVCGKAFFVRSSLTVHLRIHTGEKPFKCSVCGKAFYVVSSLKRHEKAHVEEPHHQCHECGKAFFERFTLIRHQRTHTGESPYECQQCGKSFSEKSILNRHQLIHTDRKQYVCSECGRAFCTVSSLNRHQKAHAGEPNHQCSECGKAFFDRSYLAHHQKIHTGDKPYKCSVCGKAFREKSILTRHQLVHTDRKPYVCSECGKAFYVVSSLNRHRKEHNGEPHHQCNECGKAFFDRSSFTQHQKIHTGDKPYECSVCGKAFIQRCRLTRHQRVHTGEKPFECSVCGKHFSSKSSIVLHQRRYAKQGTD", "length": 532, "header": "tr|A0A9J7G8Q4-1|A0A9J7G8Q4_CRIGR Isoform 1 of Zinc finger protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC103160501 PE=3 SV=1 CANONICAL=A0A9J7G8Q4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G8Q4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4/entry#A0A9J7G8Q4-1", "sequence": { "sequence": "MATVSPPTKCQTSVTFEDVAVTFTDEEWRHLVPVQRALYKAVMLETYETIISLGIPVPRSDMILLLKRDKPWTQDLLGSKEKEWPESISLDQETKPESLAASEGTLGESHRQQSPLCPKPKVQTLAGGSEPEKERLEAETCKKPLSLDKSLKGRSAPSKKILTKRQDQECRECGKTFFDHWSLIRHHRTHTGEKPYDCPECGKAFSQRSTLSRHLISHTGEGPYKCSVCGKAFFVRSSLTVHLRIHTGEKPFKCSVCGKAFYVVSSLKRHEKAHVEEPHHQCHECGKAFFERFTLIRHQRTHTGESPYECQQCGKSFSEKSILNRHQLIHTDRKQYVCSECGRAFCTVSSLNRHQKAHAGEPNHQCSECGKAFFDRSYLAHHQKIHTGDKPYKCSVCGKAFREKSILTRHQLVHTDRKPYVCSECGKAFYVVSSLNRHRKEHNGEPHHQCNECGKAFFDRSSFTQHQKIHTGDKPYECSVCGKAFIQRCRLTRHQRVHTGEKPFECSVCGKHFSSKSSIVLHQRRYAKQGTD", "length": 532, "header": "tr|A0A9J7G8Q4-1|A0A9J7G8Q4_CRIGR Isoform 1 of Zinc finger protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC103160501 PE=3 SV=1 CANONICAL=A0A9J7G8Q4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4/entry#A0A9J7GBA1-1", "sequence": { "sequence": "MLETYETIISLGIPVPRSDMILLLKRDKPWTQDLLGSKEKEWPESISLDQETKPESLAASEGTLGESHRQQSPLCPKPKVQTLAGGSEPEKERLEAETCKKPLSLDKSLKGRSAPSKKILTKRQDQECRECGKTFFDHWSLIRHHRTHTGEKPYDCPECGKAFSQRSTLSRHLISHTGEGPYKCSVCGKAFFVRSSLTVHLRIHTGEKPFKCSVCGKAFYVVSSLKRHEKAHVEEPHHQCHECGKAFFERFTLIRHQRTHTGESPYECQQCGKSFSEKSILNRHQLIHTDRKQYVCSECGRAFCTVSSLNRHQKAHAGEPNHQCSECGKAFFDRSYLAHHQKIHTGDKPYKCSVCGKAFREKSILTRHQLVHTDRKPYVCSECGKAFYVVSSLNRHRKEHNGEPHHQCNECGKAFFDRSSFTQHQKIHTGDKPYECSVCGKAFIQRCRLTRHQRVHTGEKPFECSVCGKHFSSKSSIVLHQRRYAKQGTD", "length": 490, "header": "tr|A0A9J7GBA1-1|A0A9J7GBA1_CRIGR Computationally mapped isoform of Zinc finger protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103160501 PE=3 SV=1 CANONICAL=A0A9J7G8Q4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103160501", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103160501", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Q4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G8Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 168, "end_pos": 195, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7G8Q4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q4" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 84, "start_aa": "Val", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GAV5-1", "uniprot_ac": "A0A9J7GAV5", "uniprot_id": "A0A9J7GAV5_CRIGR", "mass": { "chemical_mass": 55814.0, "monoisotopic_mass": 55814.0 }, "refseq": { "ac": "XP_027279378", "name": "LIM/homeobox protein Lhx6 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279378" }, "gene_names": [ { "name": "Lhx6", "type": "recommended", "evidence": [ { "id": "A0A9J7GAV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5" } ] }, { "name": "Lhx6", "type": "synonym", "evidence": [ { "id": "XP_027279378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279378" } ] } ], "protein_names": [ { "name": "LIM/homeobox protein Lhx6 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027279378", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279378" }, { "id": "A0A9J7GAV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279378" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lhx6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5", "locus": {} } ], "crossref": [ { "id": "A0A9J7GAV5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GAV5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09380", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09380", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09382", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09382", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769913", "url": "https://www.ncbi.nlm.nih.gov/gene/100769913", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769913", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769913", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GAV5", "url": "https://www.orthodb.org/?gene=A0A9J7GAV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24208:SF121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24208:SF121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279378", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHLERSGAPAAGRSSPQLEGEEDNEEEGEEEEEEEEEEEEAAAAAEAAAGTSPSLSGPSSEEAVAPAAREARTAFRPGAGAGAGPGAAGPEPPLSSTLNSLCPQGAPGPTSRRSPCCAPAEPSVPGPMYWKHESAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDTEALAGSLDKDEGRASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIYCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYSPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSNRGEKVILFQY", "length": 520, "header": "tr|A0A9J7GAV5-1|A0A9J7GAV5_CRIGR Isoform 1 of LIM/homeobox protein Lhx6 isoform X4 OS=Cricetulus griseus OX=10029 GN=Lhx6 PE=4 SV=1 CANONICAL=A0A9J7GAV5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G8Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5/entry#A0A9J7G8Q6-1", "sequence": { "sequence": "MTHLERSGAPAAGRSSPQLEGEEDNEEEGEEEEEEEEEEEEAAAAAEAAAGTSPSLSGPSSEEAVAPAAREARTAFRPGAGAGAGPGAAGPEPPLSSTLNSLCPQGAPGPTSRRSPCCAPAEPSVPGPMYWKHESAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDTEALAGSLDKDEGRASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIYCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYSPFSSPERARMVTLHGYIESHPFSVLTLPALAHLSMGTAQLPLSR", "length": 505, "header": "tr|A0A9J7G8Q6-1|A0A9J7GAV5_CRIGR Computationally mapped isoform of LIM/homeobox protein Lhx6 isoform X4 OS=Cricetulus griseus OX=10029 GN=Lhx6 PE=4 SV=1 CANONICAL=A0A9J7GAV5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5/entry#A0A9J7GAV5-1", "sequence": { "sequence": "MTHLERSGAPAAGRSSPQLEGEEDNEEEGEEEEEEEEEEEEAAAAAEAAAGTSPSLSGPSSEEAVAPAAREARTAFRPGAGAGAGPGAAGPEPPLSSTLNSLCPQGAPGPTSRRSPCCAPAEPSVPGPMYWKHESAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDTEALAGSLDKDEGRASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIYCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYSPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSNRGEKVILFQY", "length": 520, "header": "tr|A0A9J7GAV5-1|A0A9J7GAV5_CRIGR Isoform 1 of LIM/homeobox protein Lhx6 isoform X4 OS=Cricetulus griseus OX=10029 GN=Lhx6 PE=4 SV=1 CANONICAL=A0A9J7GAV5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5/entry#A0A9J7KAV4-1", "sequence": { "sequence": "MTHLERSGAPAAGRSSPQLEGEEDNEEEGEEEEEEEEEEEEAAAAAEAAAGTSPSLSGPSSEEAVAPAAREARTAFRPGAGAGAGPGAAGPEPPLSSTLNSLCPQGAPGPTSRRSPCCAPAEPSVPGPMYWKHESAAPALPEGCRLPAEGGPATDQVMAQPGSGCKATTRCLEGTAPPAMAQSDTEALAGSLDKDEGRASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIYCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPSALSDDIHYSPFSSPERARMVTLHGYIESMGHLRETGG", "length": 489, "header": "tr|A0A9J7KAV4-1|A0A9J7KAV4_CRIGR Computationally mapped isoform of LIM/homeobox protein Lhx6 isoform X6 OS=Cricetulus griseus OX=10029 GN=Lhx6 PE=4 SV=1 CANONICAL=A0A9J7GAV5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 111, "start_aa": "Thr", "end_pos": 111, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr111", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 206, "start_aa": "Thr", "end_pos": 206, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr206", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Q6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Q6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769913", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769913", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5" } ], "pmid": "" }, { "name": "forebrain neuron development", "id": "GO:0021884", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021884", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GAV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 374, "end_pos": 434, "start_aa": "Lys", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7GAV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV5" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 285, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 111, 206 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G8R0-1", "uniprot_ac": "A0A9J7G8R0", "uniprot_id": "A0A9J7G8R0_CRIGR", "mass": { "chemical_mass": 35032.0, "monoisotopic_mass": 35032.0 }, "refseq": { "ac": "XP_027276730", "name": "olfactory receptor 1019", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276730" }, "gene_names": [ { "name": "LOC100753523", "type": "recommended", "evidence": [ { "id": "A0A9J7G8R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0" } ] }, { "name": "LOC100753523", "type": "synonym", "evidence": [ { "id": "XP_027276730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276730" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7G8R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1019", "type": "synonym", "evidence": [ { "id": "XP_027276730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276730" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276730" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753523", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0", "locus": {} } ], "crossref": [ { "id": "A0A9J7G8R0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G8R0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15410", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15410", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753523", "url": "https://www.ncbi.nlm.nih.gov/gene/100753523", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753523", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753523", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G8R0", "url": "https://www.orthodb.org/?gene=A0A9J7G8R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276730", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLENFTVFTDFLFSGLSSRQDVQQALFVFFFLIYGLTVIANLGMVLLIKLDPRLHTPMYYFLSNLSFCDVCYSSTVSPKMLADFLSEQKRIAYSLCAVQMYFFGAFADVECLMLAIMAYDRYVAICNPLLYTIAMSKKVCIQLVAVAYVVGLVDSAIHTCCTFRLSFCNSNVINHFFCDIPPLLALSCSDTSVNEIVMFTFIGCVVGCSIVTVLLSYFYIIATICRMNSAEGRHKAFSTCASHLTAVAIFHGTLLFMYFRPSSSYSMDTDKMASVFYTVVIPMLNPLIYSLRNKDVKGALKKAISINLWPR", "length": 312, "header": "tr|A0A9J7G8R0-1|A0A9J7G8R0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100753523 PE=3 SV=1 CANONICAL=A0A9J7G8R0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G8R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0/entry#A0A9J7G8R0-1", "sequence": { "sequence": "MTLENFTVFTDFLFSGLSSRQDVQQALFVFFFLIYGLTVIANLGMVLLIKLDPRLHTPMYYFLSNLSFCDVCYSSTVSPKMLADFLSEQKRIAYSLCAVQMYFFGAFADVECLMLAIMAYDRYVAICNPLLYTIAMSKKVCIQLVAVAYVVGLVDSAIHTCCTFRLSFCNSNVINHFFCDIPPLLALSCSDTSVNEIVMFTFIGCVVGCSIVTVLLSYFYIIATICRMNSAEGRHKAFSTCASHLTAVAIFHGTLLFMYFRPSSSYSMDTDKMASVFYTVVIPMLNPLIYSLRNKDVKGALKKAISINLWPR", "length": 312, "header": "tr|A0A9J7G8R0-1|A0A9J7G8R0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100753523 PE=3 SV=1 CANONICAL=A0A9J7G8R0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"UniProtKB", "id": "A0A9J7G8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8R0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G8R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279394" } ] }, { "annotation": "Responsible for the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with GFM2. Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8R5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8R5#function" }, { "database": "UniProtKB", "id": "ARBA00055779", "url": "https://www.uniprot.org/uniprotkb/ARBA00055779#function" }, { "database": "UniProtKB", "id": "A0A9J7GAW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAW3#function" }, { "database": "UniProtKB", "id": "A0A9J7H120", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H120#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAW3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrrf", "url": 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279684" } ] }, { "annotation": "Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin. Stimulates PI4KB kinase activity. Involved in long-term synaptic plasticity through its interaction with PICK1. 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"common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ncs1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8V8", "locus": {} } ], "crossref": [ { "id": "A0A9J7G8V8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G8V8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757383", "url": "https://www.ncbi.nlm.nih.gov/gene/100757383", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279684", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8V8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0B3", "database": 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"MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV", "length": 190, "header": "tr|A0A8C2MZP2-1|A0A8C2MZP2_CRIGR Computationally mapped isoform of Neuronal calcium sensor 1 OS=Cricetulus griseus OX=10029 GN=Ncs1 PE=3 SV=1 CANONICAL=A0A9J7G8V8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8V8/entry#A0A9J7G8V8-1", "sequence": { "sequence": "MPELWMVTSPVCPHPRTRTERGFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV", "length": 191, "header": "tr|A0A9J7G8V8-1|A0A9J7G8V8_CRIGR Isoform 1 of Neuronal calcium sensor 1 OS=Cricetulus griseus OX=10029 GN=Ncs1 PE=3 SV=1 CANONICAL=A0A9J7G8V8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H0B3-1", "url": 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"locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8V8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757383", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757383", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8V8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8V8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8V8", "url": 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"evidence": [ { "id": "A0A9J7G8X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8X1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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} ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 285, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 63, "end_pos": 65 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G8Z0-1", "uniprot_ac": "A0A9J7G8Z0", "uniprot_id": "A0A9J7G8Z0_CRIGR", "mass": { "chemical_mass": 327245.0, "monoisotopic_mass": 327245.0 }, "refseq": { "ac": "XP_027277860", "name": "microtubule-associated protein 1A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277860" }, "gene_names": [ { "name": "Map1a", "type": "recommended", "evidence": [ { "id": "A0A9J7G8Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Z0" } ] }, { "name": "Map1a", "type": "synonym", "evidence": [ { "id": "XP_027277860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277860" } ] } ], "protein_names": [ { "name": "Microtubule-associated protein 1A", "type": "synonym", "evidence": [ { "id": "A0A9J7G8Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Z0/entry#names_and_taxonomy" } ] }, { "name": "microtubule-associated protein 1A", "type": "synonym", "evidence": [ { "id": "XP_027277860", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277860" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277860" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Z0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Map1a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Z0", "locus": {} } ], "crossref": [ { "id": "100755159", "url": "https://www.ncbi.nlm.nih.gov/gene/100755159", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026074", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026074", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057480", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057480", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755159", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755159", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G8Z0", "url": "https://www.orthodb.org/?gene=A0A9J7G8Z0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13843", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13843", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13843:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13843:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G8Z0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEARTARPGSVAMETTRELGLPSSGASPAQNPAEPLCEAGAAVAAARWDLRKYSLLIVIGDIGTESQLRAVRAHLEQGILSWNIDLSSFDLNQQLRLFITRHLAHFSSEVKGQRTLCHQSEILETIILVNPSADSINSEVHHLLSTPSAHKLLILSGQTLEPEGDLILQSGTYSYQNFVRVLHSPEIAQLLSNRDPGIQASLTVSCLGEGDWSHLGLSSSKETLHLQLNPEPVLPTMDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYSDWVKNLISPELGVVFFNVPDKLRLPDASRKAKRSIEEACLTLQHLNRLGIQAEPLYRVVSNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLANGKEAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQRDLAAGAVPANLKPSKIKHRADSKESLKAAPKTAVSKLAKREEVLEEGAKEARSELAKELAKTEKKAKESSEKPPEKPSKPERVRMESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKEFKKEEGRKEEKKDAKKDEKRKDNKTEVKKFSKPDLKPFTPEVRKTLYKAKAPGRIKTDKGRVARGEKESSGEPRTPPAQRGPMPLPTVSGHRELALSSPEDLTQDFEELKREEREQRDTGLGEKPLHVDTTEQGHPSTAIQEGHPSVPGLDQGHVIMEKEVVPDFLEDKGSKNRGLDSEAETETEKETWEEKKQREVEKMPENAETREESEPEVKEDVIEKAELEEMEEAHPSDEDEEETKAESFYQKHMQEALKVIPKNREALGGRELGFQGKAPEKETSSLLSSLATPAGAIEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFPTSTYDLSGPEGPGPFEASQPTDSTVPATSSKTYGASEPELTYPPNMVAAPLAEEEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGELEKKGEAVGRGLTGEKAVEKKQETDVRASEKLPSQYAAVFGAPGHVLHPGEPALGEVEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSEPQDFQEDSWGDKHTPGADKADAEKQTVKPGPEKGILGEGTVPLPRSPQAQEAPVSIVGGQTGCTIQLLPEQDKAIVFETGEAGSILGAEALPREVKELREEHQELQRDEVLRLTDQSLSPEDAESLSVLSVVSPDIAKQEATPRSPCSPKEQHLHKDLWPMVSPEDTQSLSFSEESPSKETSLDISSKQLSPESLGTLQFGELSLGKEERGPLIKAEDPSCHLAPVSIPDSHIATVSPTTDETAGEASVTDESPAGKLPSSSFSHSALSGDRKHSPGEVTGPGEHMTSDSSLTKSPESLSSPAMEDLGMQWEGKAPGLKDRAAEQREEEVVLKDENLQQNRILHEKVAVVQQGTAMHQIDKALDEKNKLGEQLDKTSEKKGRDLDQKDAAIGLAKTPEPKDKDLEQKDQVPAEKDKASEQKGTALQQSQAPEPKDREQKHRDLEQKDKVLEPKDKTPEEKDRTLGQKDRAPEHSVPEPRQTDSTPEQKSKANKEQKDEASEEKDLTLELKDWALGKKSGTLDQDIRAAEQKDRTLKEEDKAQEQKSSFLEDKTTTLTETILDQKSPEEAKAVEQKDDAVVEKTRAPGVEESTAQEGKAQEQDKKYWKEQDVVQGWRETSPTRGEPVGEQKEPVPAWEGKSPEQEVRAWRDRDTTLQQDAYWRELSCDRKVWFPHELDGQGAHSRYCEERESTFLDEGTDEQAMTPLQHTPRNPWASDFKDFQEPLPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPSSPPEMTGQRVPPAPGQESPVPDTKPAPPSRNEPTTPSWLAEIPPWVPKDRPLPPAPLSPAPAPPTPAPEPQTPVPFSWGIAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREGEGGAPDRSPCSSKVPEAGQSHTPRDTEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPSCPTREPPLGASGDWPPSLSSKEEAAGRNTSAEKESFSPVSPSNLQSDTSTFSYASLAGPAVPPRQEPEPGPKVEPSLTPPAVPPRAPISLSKGPSPALNGSTVSCSPDRRTPSPKELGRGHWDDSTSDSDLEKGAREQPEKEAQSPSPHHPMPVGHPSMWPETEAHTSLSSDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALVPGTPTRPRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFPPGLAAAEQSAGELGPGMEPAPHSLWDLAPLSPAPLPSLDLAPAPAPSLLGDMDDGTLPCRLECSGELTKKPSPFQSPSGDQAANGLAETSPNPPGLATAKAEKEEAEACTAWERGSWPEGAERSSQPDTLLSSEQLHAGKSPGGPPCSLSPEVEAGPQGCATEPRPHCGELSPSFLNPPLPPFTDDCDLSTEEAQLVGKGGRRRTGKPGATGGPCPMADETPPTSASDSGSSQSDSDVPPETEECPSITAEAVLDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPAPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRLGRRTPSRAKPASPARRLDIRGKRSPTPGKGPADRTSRTLPRPRSTPSQVTPAEEKDGHSPMSKGLVNGLKAGPTALGSKGGSGPPVYVDLAYIPNHCSGKTADLDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGENLQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSSTVVMQDESFPACKIEF", "length": 3015, "header": "tr|A0A9J7G8Z0-1|A0A9J7G8Z0_CRIGR Isoform 1 of Microtubule-associated protein 1A OS=Cricetulus griseus OX=10029 GN=Map1a PE=4 SV=1 CANONICAL=A0A9J7G8Z0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G8Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Z0/entry#A0A9J7G8Z0-1", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279860" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100767550", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936", "locus": {} } ], "crossref": [ { "id": "A0A9J7G936", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G936", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22115", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22115", "database": "CDD", "categories": [ "Protein 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}, { "id": "XP_027279860", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279860", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N4N3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N4N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4N3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G936-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JWX7", "url": 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"https://www.uniprot.org/uniprotkb/A0A9J7G936/entry#A0A8C2N4N3-1", "sequence": { "sequence": "MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 436, "header": "tr|A0A8C2N4N3-1|A0A8C2N4N3_CRIGR Computationally mapped isoform of F-box/LRR-repeat protein 20 OS=Cricetulus griseus OX=10029 GN=LOC100767550 PE=4 SV=1 CANONICAL=A0A9J7G936-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G936-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936/entry#A0A9J7G936-1", "sequence": { "sequence": "MWVPAQAAGQVTRLGLGTASRKLAQVPRGSMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 452, "header": "tr|A0A9J7G936-1|A0A9J7G936_CRIGR Isoform 1 of F-box/LRR-repeat protein 20 OS=Cricetulus griseus OX=10029 GN=LOC100767550 PE=4 SV=1 CANONICAL=A0A9J7G936-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GD61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936/entry#A0A9J7GD61-1", "sequence": { "sequence": "MLVTEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 427, "header": "tr|A0A9J7GD61-1|A0A9J7GD61_CRIGR Computationally mapped isoform of F-box/LRR-repeat protein 20 OS=Cricetulus griseus OX=10029 GN=LOC100767550 PE=4 SV=1 CANONICAL=A0A9J7G936-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JWX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936/entry#A0A9J7JWX7-1", "sequence": { "sequence": "MFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 422, "header": "tr|A0A9J7JWX7-1|A0A9J7JWX7_CRIGR Computationally mapped isoform of F-box/LRR-repeat protein 20 OS=Cricetulus griseus OX=10029 GN=LOC100767550 PE=4 SV=1 CANONICAL=A0A9J7G936-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 433, "start_aa": "Thr", "end_pos": 433, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr433", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767550", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767550", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "pmid": "" }, { "name": "Schaffer collateral - CA1 synapse", "id": "GO:0098685", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098685", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "pmid": "" }, { "name": "regulation of synaptic vesicle exocytosis", "id": "GO:2000300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000300", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "pmid": "" }, { "name": "regulation of protein catabolic process at presynapse, modulating synaptic transmission", "id": "GO:0099575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099575", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G936" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 100, "end_pos": 102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 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Coassembles with DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G948", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948#function" }, { "database": "UniProtKB", "id": "ARBA00094477", "url": "https://www.uniprot.org/uniprotkb/ARBA00094477#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G948", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Drc1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948", "locus": {} } ], "crossref": [ { "id": "A0A9J7G948", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G948", "database": "AlphaFoldDB", "categories": [] }, { "id": "100759288", "url": "https://www.ncbi.nlm.nih.gov/gene/100759288", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039750", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039750", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759288", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759288", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LDFMMAR", "url": "https://omabrowser.org/oma/group/LDFMMAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G948", "url": "https://www.orthodb.org/?gene=A0A9J7G948", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21625", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21625", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21625:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21625:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016819668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G948", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G948-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNLLANLGFFDQNDEEHLAATIHGPSVYSDNPQERIQARRLRIAARQEARRREALGEYLDGKKESEEEQSKSYKQKEESRLKLTKLLLCGTELVTNIQVATDIREIHRRVEEEEVKRQRLEKLENEVKTSQDKFDEITAKWEEGRQKRIPQELWEMLNTQQLHCAGLIEDKNKLISELQQELKIKDDQFVKDLKKQSDDISLLLERMEEQVKSVMKNFRQELMQIEKAFESERQELLSNNMKKWERALQGHNAKELEYLINRMKKVEDYEKQLNKQRVWDCEEYNTIKIKLERDIQILEQQLQQMKATYQLNQEKLEYNFQVLKKRDEESTVIKSQQKRKLNRLHDILNNLRTKYAKQIKQFQEENQTLTSDFKRLVGQFKELQKAMRHFAIIDAEKFREIWLMNEEEAKVLVQRAFDVDKVISSQHLGLPWKMPDFWFLKNVGPISMQQQKSATQILEELLLQTEEDETEETSEDESYMDLPKQVSAKTTKKILMLLCDESGFLIESKLLSLLLPLEKNECYLLRLDAIFSALGIESEDDLYKLVNFFLRYRSHRLSSIQYSTSTQTERTSLISTMERMSLLSQTDRKSLVSKSEVDSMVLPEDLPEDDNESLVSKELREESLASPKLIHPNDVLKILEAFVMGLKKPKDTRPVLRVKRDTRDNSKDTEYWTSLALVIPLAKQNLWDALYKALEKYYLVLTQRAKLLMENDSLEEQNAEMQSLLQQYLQAKVNSELQIPPTQSFRMPTK", "length": 750, "header": "tr|A0A9J7G948-1|A0A9J7G948_CRIGR Isoform 1 of Dynein regulatory complex protein 1 OS=Cricetulus griseus OX=10029 GN=Drc1 PE=3 SV=1 CANONICAL=A0A9J7G948-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G948-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948/entry#A0A9J7G948-1", "sequence": { "sequence": "MNLLANLGFFDQNDEEHLAATIHGPSVYSDNPQERIQARRLRIAARQEARRREALGEYLDGKKESEEEQSKSYKQKEESRLKLTKLLLCGTELVTNIQVATDIREIHRRVEEEEVKRQRLEKLENEVKTSQDKFDEITAKWEEGRQKRIPQELWEMLNTQQLHCAGLIEDKNKLISELQQELKIKDDQFVKDLKKQSDDISLLLERMEEQVKSVMKNFRQELMQIEKAFESERQELLSNNMKKWERALQGHNAKELEYLINRMKKVEDYEKQLNKQRVWDCEEYNTIKIKLERDIQILEQQLQQMKATYQLNQEKLEYNFQVLKKRDEESTVIKSQQKRKLNRLHDILNNLRTKYAKQIKQFQEENQTLTSDFKRLVGQFKELQKAMRHFAIIDAEKFREIWLMNEEEAKVLVQRAFDVDKVISSQHLGLPWKMPDFWFLKNVGPISMQQQKSATQILEELLLQTEEDETEETSEDESYMDLPKQVSAKTTKKILMLLCDESGFLIESKLLSLLLPLEKNECYLLRLDAIFSALGIESEDDLYKLVNFFLRYRSHRLSSIQYSTSTQTERTSLISTMERMSLLSQTDRKSLVSKSEVDSMVLPEDLPEDDNESLVSKELREESLASPKLIHPNDVLKILEAFVMGLKKPKDTRPVLRVKRDTRDNSKDTEYWTSLALVIPLAKQNLWDALYKALEKYYLVLTQRAKLLMENDSLEEQNAEMQSLLQQYLQAKVNSELQIPPTQSFRMPTK", "length": 750, "header": "tr|A0A9J7G948-1|A0A9J7G948_CRIGR Isoform 1 of Dynein regulatory complex protein 1 OS=Cricetulus griseus OX=10029 GN=Drc1 PE=3 SV=1 CANONICAL=A0A9J7G948-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 742, "start_aa": "Thr", "end_pos": 742, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr742", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G948", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G948", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759288", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759288", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y743-1", "protein_name": "Dynein regulatory complex protein 1", "gene_name": "DRC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTSSSPNGLKDRCRQPQSSTSSPQTDSPAPDPTTSTSSTSSGTTCLELAAVLGASLAPHEQWAQDHGGWATLSCLFSALVSLLNCAVCAGMESQALQGDLSTLGRQCAKDSVFFPFLPRQALGENEEPKEEAEEVEEERSSHKQVEESRQKLAKLLFEGTRMVTDIQVAVDLRETQRRAEQAELKLQRVEKLENEARSSADKFEEITSKWALAKDMTIPQELWQLLNQQQQLCTQLLEEKNKLIGELQQELKNKDEQYVQTIKKQSDDIHLLLERMEEQIRMMLKTYRRNIHQIEKAFELERRELLDSNRKKWEEAIQALNTKELEYLHARVRKVEEFEKQLNQLRVQDEEEYNSMKIHLESDVQNLERQLQHMKAVYLVNQEKLEYNLQVLKKQDEENTIIRSQQKRKLNRLHSLLSNLRTKLVKQEKQFREENQSLAADCERITGQCKEVQRRMRHFAASDAEKFMKIWLMNEEEAKGLMRKALDADRIIHTQQLGLPWEEPHYWFLNNVGPFRHYKAKRMATKLAAEVLTEGTSGAREKKEEKEEVGSGEGQKENPAKAGDTVTPLQNISKKTAKRILELVSDESGFLIERKLLRPLRALGKHECTLLRLDSIFSALEIDSEDDLYQLMDFFLKYKAKEEALSQSQGSPGGEDITALGEDRADGESNAQSDELKSSQGPLGSLPSVYIHADDVLKILKAFVQDFHKLREEDNSAKEVLQVRDSSKDGEYWEALAHVIPEPTLKLWDALAVALEEYYNILTRRGNLIAESAVLQQQNSELSLMLEQFIASGVNSMLLSPPVQQMDPNLPCPGEPR", "length": 817 }, "evidence": [ { "id": "A0A9J7G948", "url": "https://omabrowser.org/oma/group/A0A9J7G948/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1QRC1-1", "protein_name": "Dynein regulatory complex protein 1", "gene_name": "drc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHQTEAFAAGEEAEELRPSVESDKKEERILARRLRLAARKEAQTKQRLGEDDLGKEDVKEETRKSQKEVEHRERRMAKLKSDGLELVTNIQVAADARESDRRTELEEGHRLRREKLENEAKSSQEKFEEINRKWTDAKMKQTPLDLRDALSSQQQLCEQIIADKNKLISELQQELKASDDRYVKDLKRQAKDIDLLVERMEEQISTLKKSYREDLHQIENSLDEERRTLLTKHKKKWEHERKDRNEKELKNMMQSLSVMEEYADLLQKLRVQTAEEYNIDKIRMDTEVQKLRMKVQQTKFNCHMNEEKLDYKYEVLKKKEEENAIIKSQLKRKIIRMQDVLNNLKSKLTKQEKQSKAGNQSLSNDYTRISQQYKDMQKKARHFAALDAERLEKLWLMCEDEAKALTHRALETDRVIHEQQLGLEWASPPLPFMERSGAVQQKTFRTATQAAADTLKGEPEGGLDEDTAAGLNKRTVKSILELLCDEMGFLVESKLLMLLSPLEKNEQSLIKLDAIFSAIGIESEKDVYKMAEFFMNYRQHESKYTKDETANGQGESAEELSNLIHTEDLLAALKDFTAQFCRQDVHASHKSSILGLDMRDDSEDAAYWESIANVMPESKLKLWDALDTALNKYHAVLTERTELLMETQNIQQQNSELRQLLHLYTTSKAQ", "length": 670 }, "evidence": [ { "id": "A0A9J7G948", "url": "https://omabrowser.org/oma/group/A0A9J7G948/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q32KY1-1", "protein_name": "Dynein regulatory complex protein 1", "gene_name": "DRC1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNPPGSLGVLEEKEEEHLAPPILGPSIHSDNPQERIQARRLRIAARLEARRREALGEYLDGKKESEEDQSKSYKQKEESRLKLAKLLLCGTELVTNIQVAADIREIHRRVEEEEIKRQRLEKLENEVKTSQDKFDEITVKWEEGKQRRIPQELWEMLNAQQVHCAGLIEDKNKLISELQQELKMKDDQYVKDLKKQSDDICLLLERMEEQVKNVMKTFRQELQNIEKAFEVERQELLTSNKKKWERALQAHNAKELEYLMNRIKKVEDYEKQLNKQRIWDCEEYNTIKIKLEQDVQILEQQLQQMKATYQLNQEKLEYNFQVLKKRDEESTVIKSQQKRKINRLHDVLNNLRSKYNKQVKQFQEENQSLTSDYKRLVLQFKELQKAMRHFALIDDKRFREIWLMNEEEAKDLINRAFDVDRIISTHHLGLPWMAPDFWFLKNVGPISQQQQKSATQILEEVLMEAEKEGADEDSSESETYLDLPKQVSARTTRKILMLLCDESGFLIESKLLSLLLPLEKNECYLLRLDAVFSALGIENEDDLYKLVNFFLKYQTHHSPSSQEPLDLRAEKERSLVDGKSQEKEPPPSPKLIHPNDVLKILEAFVMSLRKPRDFWVPVKLLKAVRDDSKDSEYWEALTTVIPATTLNLWDALYTALEKYHLVLTQRAELLIENSSLERQNTELQQLLQQYLDTKINSELQVPPTQVFRVPTK", "length": 712 }, "evidence": [ { "id": "A0A9J7G948", "url": "https://omabrowser.org/oma/group/A0A9J7G948/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3USS3-1", "protein_name": "Dynein regulatory complex protein 1", "gene_name": "Drc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNPSGTIGVLEQNGEEHLATPILGPSVHSDNPQERIQARRLRIAARQEARRREALGEYLDGKKESEEEQSKSYKQKEESRLKLTKLLLCGTELVTNIQVAADVREIHRRVEEEETKRQRLEKLENEVKTSQDKFDEITAKWEEGRRKRIPQELWEMLNSQQVHCAELIEDKNKLANELQQELKIKDDQYVKDLKKQSEDITLILERMEEQVKNVMKNFRQELIHIEKAFESERQELLSSNKKKWERALQAHNAKELEYLTNRMKKVEDYEKQLNKQRVWDCEEYNTIKIKLEQDVQILEQQLQQMKATYQLNQEKLEYNFQVLKKRDEESTVIKSQQKRKLNRLHDVVNNLRTKYTKQIRQFQDDNQSLTSDYKRLVTQFKDLQKALRHFIIIDEEKFREIWLMNEAEAKELAQRAFDVDRIIHSQHLGLPWNMPDLWFLNNVGPISLQQQKSVTQILEELLLQTEDEATEAAMSEDEDYMDLPNQISAKTTTKVLMLLCDESGFLIESKLLSLLHPLEKSECYLLRLDAIFSALAIEDEDDLYKLVNFFLRYRAHRLSSAQASSSIHSNVERTSLMSALERLSLMSQTDKGSMVSKSDQEPTEQEDEQEGDNASLSSRELEEQEDLSSPRFIHPNDVLKILEAFVTGLKKPKDAQPVLKLKKETRDNSKDTEYWESLAAVIPFFKQNLWDALYKALEKYYLVLTERAKLLMENESLEQQNAEMQSLLQQYLQAKVNTELQIPPTQGFRMPSK", "length": 753 }, "evidence": [ { "id": "A0A9J7G948", "url": "https://omabrowser.org/oma/group/A0A9J7G948/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5XI65-1", "protein_name": "Dynein regulatory complex protein 1", "gene_name": "Drc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPSGSIGVLEQNGEEHLAAPILGPSVNSDNPQERIQARRLRIAARQEARRREALGEYLDGKKESEEEQSKSYKQKEESRLKLTKLLLCGTELVTNIQVAADIREIHRRVEEEETKRQRLEKLENEVKTSQDKFDEITSKWEEGRQKRIPQELWEMLNNQQVHCAGLVEDKNKLISELQQELKIKDDQYVKDLKKQSEDITVLLERMEEQVKSVMKNFRQELNYIEKAFESERQELLTTNKKKWERALQAHNAKELEYLINRMKRVEDYEKQLNRQRVWDCEEYNSIKIKLEQDVQILEQQLQQMKATYQLNQEKLEYNFQVLKKRDEESTVIKSQQKRKLNRLHDILNNLRTKYSKQIKQFQEDNQSLTSDYKRLVTQFKDLQKAIRHFIIIDQDKFREIWLMNEAEAKELAQRAFDVDKIIHSQHLGLPWKIPNFWFLNNVGPISLQQQQKSVTQILEELLLQSEDEGTETAMSEDESYMDLPNQVSAKTTKKILVLLCDESGFLIESKLLSLLLPLEKSECYLLRLDAIFSALGIESEDDLYKMVNFFLRFKAHHLSSAQVSISTHSNAERTSLVSALQHMSLMSQTDRRSSASKSDGDPTELEDQQGSDNGSLMGRELVEQEDLSSPMFIHPNDVLKILDAFVTGLKKPKDARPVQRLKKDTRNNLKDTEYWESLAMVIPFSKQNLWDALFKALEKYYLVLTQRAKLLMENDSLEQQNAEMQSLLQQYLQAKVNLELQVPPTQGFRMPSK", "length": 754 }, "evidence": [ { "id": "A0A9J7G948", "url": "https://omabrowser.org/oma/group/A0A9J7G948/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96MC2-1", "protein_name": "Dynein regulatory complex protein 1", "gene_name": "DRC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPPGSLEALDPNVDEHLSTQILAPSVHSDNSQERIQARRLRIAARLEARRREALGEYLDGKKESEEDQSKSYKQKEESRLKLAKLLLCGTELVTNIQVAIDIREIHRRVEEEEIKRQRIEKLENEVKTSQDKFDEITSKWEEGKQKRIPQELWEMLNTQQLHCAGLLEDKNKLISELQQELKTKDDQYVKDLKKQSDDICLLLERMEEQVKNVMKTFREELYNIEKAFEVERQELLASNKKKWEQALQAHNAKELEYLNNRMKKVEDYEKQLNRQRIWDCEEYNMIKIKLEQDVQILEQQLQQRKAIYQLNQEKLEYNLQVLKKRDEESTVIKSQQKRKINRLHDILNNLRSKYAKQIKQFQEENQSLTSDYKRLVMQFKELQKAMRHFALIDDEKFWEIWLMNEEEAKDLIARAFDVDRIIHTHHLGLPWAAPDFWFLNNVGPISQQPQKSATQIVEEMLMRSEEEEAEEAAAEPESYLDLPKQISEKTTKRILMLLCDESGFLIESKLLSLLLPLEQNECYLLRLDAIFSALGIESEDDLYKLVNFFLKYRAHRLSSSLQIKPCSQASMEKASMEETSTRSELELAEQTEMEGEKEESLVEGEKEEEEETPPSPWVIHPNDVLKILEAFVMGLKKPRDSRAPLRVQKNVRDNSKDSEYWQALTTVIPSSKQNLWDALYTALEKYHLVLTQRAKLLLENSSLEQQNTELQALLQQYLNSKINSELQVPPTQVLRVPTK", "length": 740 }, "evidence": [ { "id": "A0A9J7G948", "url": "https://omabrowser.org/oma/group/A0A9J7G948/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W3J8-1", "protein_name": "Dynein regulatory complex protein 1 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDDNEDELEEHQELVSDGSVEEEEEVEPDLGPVDSWESFNDRIDGLIFNERCDKSVKKLDERRLAILNRVRQQFREAPKGVAERCQAQKSPIDQRLELSSERLNELVRFGKELVTNVRVANERRELNRRLFEGAQKNQMHVKLQRESVETMARFENIKARWTELEETNEPMLLWDQIEEQKKRIAEIMARKDEMISACQAEVDRMNAKYEFDRERQAQDLCCLVERVDHQVETLKEAYKEHIQMLRQTIEEERQIFADNAVEKWRTFFDAMNANFDEKANLVRAREQFYARQTQQINESQEELTKSTRIRLEKECERLELELRRTRDNVLMNSEKLDYNYQVLQKRNEENVIINNQQKRRVARLHEAIGRTRRGLKNLYNTGKRNIARLSSDIYKLHSNINDMESKAHQARLNNREKFDRIWEINYKELNLLVDRVYHIDRIIHEQQLAMPWSSPVPPIPNINKAKKKRNNILEKFDMRIGRVPKNRVMPNSGVNCKPDIKELPPDSLRLMRNLIRKLSDRGGFLIEERLLKILEPYSEEEKCLVRIDNIFAALRIRHLRDVKELTKVFMPYTYCPNCQPQGLSPRKCAEVFMKDQKPNRLQGAAGGQPDEKEHRSTGDTFLPKSEVAAKRCHNHYLVMEPALCLHAMNLFTSKMHKKMYEHEPGSILNAVNLIQITDAEIRNFWRQFSACFPASKCKLWKTLEHGLNHYVEVLKMRVQYDAEVVFLRRQNEELRHLLQKFTV", "length": 743 }, "evidence": [ { "id": "A0A9J7G948", "url": "https://omabrowser.org/oma/group/A0A9J7G948/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "axonemal dynein complex", "id": "GO:0005858", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005858", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G948", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cilium-dependent cell motility", "id": "GO:0060285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060285", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G948", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948" } ], "pmid": "" }, { "name": "axonemal dynein complex assembly", "id": "GO:0070286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070286", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G948", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948" } ], "pmid": "" }, { "name": "regulation of cilium movement", "id": "GO:0003352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003352", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G948", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G948", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G948" }, { "id": "PF14775", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14775" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Dynein regulatory complex protein 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 670, "end_pos": 729, "start_aa": 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Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276978" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G965", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G965" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100768432", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G965", "locus": {} } ], "crossref": [ { "id": "A0A9J7G965", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G965", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768432", "url": "https://www.ncbi.nlm.nih.gov/gene/100768432", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768432", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768432", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G965", "url": "https://www.orthodb.org/?gene=A0A9J7G965", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276978", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G965", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G965", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G965-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G965-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTFNHTNKPDFILMGLTDSKEIQLVLFVLFLLIYVVTVLGNLGMILIIRLDVQLHTPMYFFLIHLSFLDLSYSTAITPKTLQNLLTLNRSISFISCFTQLYIFILLAATECFLLSSMAYDRYIAICKPLHYPVIMSSRCCLALLTGSYMTGAVDSSVTVFVMITLHFCKSNVIHHFYCDTSPLLSLSCSDTHIVEIIIFIFAGSTILGSLITVSVSYVSILSTILKINSTSGKQKAFSTCASHLLGVTVFYSTLIFTYLKPSESYSLGKDQVASIFYTILIPMLNPLIYSLRNKEVKGAVVRLVKKRQGNRELR", "length": 315, "header": "tr|A0A9J7G965-1|A0A9J7G965_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100768432 PE=3 SV=1 CANONICAL=A0A9J7G965-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G965-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G965/entry#A0A9J7G965-1", "sequence": { "sequence": "MNTFNHTNKPDFILMGLTDSKEIQLVLFVLFLLIYVVTVLGNLGMILIIRLDVQLHTPMYFFLIHLSFLDLSYSTAITPKTLQNLLTLNRSISFISCFTQLYIFILLAATECFLLSSMAYDRYIAICKPLHYPVIMSSRCCLALLTGSYMTGAVDSSVTVFVMITLHFCKSNVIHHFYCDTSPLLSLSCSDTHIVEIIIFIFAGSTILGSLITVSVSYVSILSTILKINSTSGKQKAFSTCASHLLGVTVFYSTLIFTYLKPSESYSLGKDQVASIFYTILIPMLNPLIYSLRNKEVKGAVVRLVKKRQGNRELR", "length": 315, "header": "tr|A0A9J7G965-1|A0A9J7G965_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100768432 PE=3 SV=1 CANONICAL=A0A9J7G965-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G965", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G965" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768432", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768432", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G965", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G965" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G965", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G965" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G965", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G965" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G965", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G965" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G967-1", "uniprot_ac": "A0A9J7G967", "uniprot_id": "A0A9J7G967_CRIGR", "mass": { "chemical_mass": 73704.0, "monoisotopic_mass": 73704.0 }, "refseq": { "ac": "XP_027279915", "name": "rap guanine nucleotide exchange factor-like 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279915" }, "gene_names": [ { "name": "Rapgefl1", "type": "recommended", "evidence": [ { "id": "A0A9J7G967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G967" } ] }, { "name": "Rapgefl1", "type": "synonym", "evidence": [ { "id": "XP_027279915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279915" } ] } ], "protein_names": [ { "name": "Rap guanine nucleotide exchange factor-like 1", "type": "recommended", "evidence": [ { "id": "A0A9J7G967", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G967/entry#names_and_taxonomy" } ] }, { "name": "rap guanine nucleotide exchange factor-like 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027279915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279915" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279915" } ] }, { "annotation": "Probable guanine nucleotide exchange factor (GEF).", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G967", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G967#function" }, { "database": "UniProtKB", "id": "ARBA00059863", "url": "https://www.uniprot.org/uniprotkb/ARBA00059863#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G967", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G967" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rapgefl1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G967", "locus": {} } ], "crossref": [ { "id": "A0A9J7G967", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G967", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774035", "url": "https://www.ncbi.nlm.nih.gov/gene/100774035", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774035", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774035", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G967", "url": "https://www.orthodb.org/?gene=A0A9J7G967", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF230", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF230", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279915", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G967", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G967", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G967-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G967-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPLEKFLKKQTSQLAGRAVAGGPGGSPGCCGGPGRGGGPGGGGGPAGGPRPLQRRQSVSRLLLPAFLREPSAEPGLEPPAEEEGGEPLGGSEEPGSGGPCWLQLEEVPGPGPLGCGVPVRSPSSYSSDELSPGEPLASPPWAPLGAPERPEHLLNRVLERLAGGTTRDSGASDILLDDIVLTHSLFLPTEKFLQELHQYFVQSRSVEGPEGLGRKQACLALLLHFLDTYQGLLQEEEGAGHIIKELYLLIMKDESLYQDLREDTLRLHQLVETVELKIPEESQPPSKQVKPLFRHFRRIDSCLQTRVAFRGSDEIFCRVYMPDHSYVTIRSRLSASVQDILGSVTEKLQYSEEPTEREDALILVAVASSGEKVLLQPTEDCVFTTLGINSHLFACTRDSYEALVPLPEEIQVSPGDTEIHRVEPEDIANHLTAFHWELFRCVHELEFVDYVFHGERGRRETANLELLLQRCSEVTHWVATEVLLCEAPGKRVQLLKKFIKIAAICKQNQDLLSFYAVVMGLDNAAVSRLRLTWEKLPGKFKNLFRKFENLTDPCRNHKSYREIISKMKPPVIPFVPLILKDLTFLHEGSKTLVDGLVNIEKLHSVAEKVRTIRKYRSRPLCLDMEASPHHLQTKAYVRQFQVIDNQNLLFELSYKLEANSQ", "length": 662, "header": "tr|A0A9J7G967-1|A0A9J7G967_CRIGR Isoform 1 of Rap guanine nucleotide exchange factor-like 1 OS=Cricetulus griseus OX=10029 GN=Rapgefl1 PE=4 SV=1 CANONICAL=A0A9J7G967-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G967-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G967/entry#A0A9J7G967-1", "sequence": { "sequence": "MKPLEKFLKKQTSQLAGRAVAGGPGGSPGCCGGPGRGGGPGGGGGPAGGPRPLQRRQSVSRLLLPAFLREPSAEPGLEPPAEEEGGEPLGGSEEPGSGGPCWLQLEEVPGPGPLGCGVPVRSPSSYSSDELSPGEPLASPPWAPLGAPERPEHLLNRVLERLAGGTTRDSGASDILLDDIVLTHSLFLPTEKFLQELHQYFVQSRSVEGPEGLGRKQACLALLLHFLDTYQGLLQEEEGAGHIIKELYLLIMKDESLYQDLREDTLRLHQLVETVELKIPEESQPPSKQVKPLFRHFRRIDSCLQTRVAFRGSDEIFCRVYMPDHSYVTIRSRLSASVQDILGSVTEKLQYSEEPTEREDALILVAVASSGEKVLLQPTEDCVFTTLGINSHLFACTRDSYEALVPLPEEIQVSPGDTEIHRVEPEDIANHLTAFHWELFRCVHELEFVDYVFHGERGRRETANLELLLQRCSEVTHWVATEVLLCEAPGKRVQLLKKFIKIAAICKQNQDLLSFYAVVMGLDNAAVSRLRLTWEKLPGKFKNLFRKFENLTDPCRNHKSYREIISKMKPPVIPFVPLILKDLTFLHEGSKTLVDGLVNIEKLHSVAEKVRTIRKYRSRPLCLDMEASPHHLQTKAYVRQFQVIDNQNLLFELSYKLEANSQ", "length": 662, "header": "tr|A0A9J7G967-1|A0A9J7G967_CRIGR Isoform 1 of Rap guanine nucleotide exchange factor-like 1 OS=Cricetulus griseus OX=10029 GN=Rapgefl1 PE=4 SV=1 CANONICAL=A0A9J7G967-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G990", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G990" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G990", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G990" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762538", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762538", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G990", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G990" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G990", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G990" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G990", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G990" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G990", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G990" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 204, "end_pos": 206 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613745.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016829728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829728" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Osbpl7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0", "locus": {} } ], "crossref": [ { "id": "A0A9J7G9Q0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G9Q0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13287", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13287", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754782", "url": "https://www.ncbi.nlm.nih.gov/gene/100754782", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754782", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754782", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G997", "url": "https://www.orthodb.org/?gene=A0A9J7G997", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G9Q0", "url": "https://www.orthodb.org/?gene=A0A9J7G9Q0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JN25", "url": "https://www.orthodb.org/?gene=A0A9J7JN25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JVF2", "url": "https://www.orthodb.org/?gene=A0A9J7JVF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10972:SF85", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10972:SF85", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01237", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01237", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016829728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829728", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G997", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G997", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G997-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G997-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"MDPGKMGAQELAAKGPTSRNLKGGLQGNCGRGVAKPWRDPPGEGDILPFAPPSSSGSTLSFLMDFQEKDTPSLAESTQSSKPSSTQQASELWEVVEEPRGRLGAEDIMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILQYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFQSWVAQLRAHRLAQRLDMPGATHRKAPGTQMLTAGSASALPGVGPREKVSSWLRDSDGLDRCSHALLECQGKLQELHKLLQSLESLHRIPSAPVIPTHQASVTTERPKKGKRTSRMWCTQGFSKDDTIGRVGRLHGSVPNLSRYLESRDSSGHRGLPPPDYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRELHQGSELSRVTVSEAPEGQRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASSSENEGSEEEESCASEITTSLSEEVLDLRGADRYQKGACVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRNGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW", "length": 899, "header": "tr|A0A9J7G9Q0-1|A0A9J7G9Q0_CRIGR Isoform 1 of Oxysterol-binding protein 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"MGAQELAAKGPTSRNLKGGLQGNCGRGVAKPWRDPPGEGDILPFAPPSSSGSTLSFLMDFQEKDTPSLAESTQSSKPSSTQQASELWEVVEEPRGRLGAEDIMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILQYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFQSWVAQLRAHRLAQRLDMPGATHRKAPGTQMLTAGSASALPGVGPREKVSSWLRDSDGLDRCSHALLECQGKLQELHKLLQSLESLHRIPSAPVIPTHQASVTTERPKKGKRTSRMWCTQGFSKDDTIGRVGRLHGSVPNLSRYLESRDSSGHRGLPPPDYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRELHQGSELSRVTVSEAPEGQRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASSSENEGSEEEESCASEITTSLSEEVLDLRGADRYQKGACVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRNGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW", "length": 894, "header": "tr|A0A9J7G997-1|A0A9J7G9Q0_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl7 PE=3 SV=1 CANONICAL=A0A9J7G9Q0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0/entry#A0A9J7G9Q0-1", "sequence": { "sequence": "MDPGKMGAQELAAKGPTSRNLKGGLQGNCGRGVAKPWRDPPGEGDILPFAPPSSSGSTLSFLMDFQEKDTPSLAESTQSSKPSSTQQASELWEVVEEPRGRLGAEDIMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILQYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFQSWVAQLRAHRLAQRLDMPGATHRKAPGTQMLTAGSASALPGVGPREKVSSWLRDSDGLDRCSHALLECQGKLQELHKLLQSLESLHRIPSAPVIPTHQASVTTERPKKGKRTSRMWCTQGFSKDDTIGRVGRLHGSVPNLSRYLESRDSSGHRGLPPPDYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRELHQGSELSRVTVSEAPEGQRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASSSENEGSEEEESCASEITTSLSEEVLDLRGADRYQKGACVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRNGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW", "length": 899, "header": "tr|A0A9J7G9Q0-1|A0A9J7G9Q0_CRIGR Isoform 1 of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl7 PE=3 SV=1 CANONICAL=A0A9J7G9Q0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JN25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0/entry#A0A9J7JN25-1", "sequence": { "sequence": "MDFQEKDTPSLAESTQSSKPSSTQQASELWEVVEEPRGRLGAEDIMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILQYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFQSWVAQLRAHRLAQRLDMPGATHRKAPGTQMLTAGSASALPGVGPREKVSSWLRDSDGLDRCSHALLECQGKLQELHKLLQSLESLHRIPSAPVIPTHQASVTTERPKKGKRTSRMWCTQGFSKDDTIGRVGRLHGSVPNLSRYLESRDSSGHRGLPPPDYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRELHQGSELSRVTVSEAPEGQRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASSSENEGSEEEESCASEITTSLSEEVLDLRGADRYQKGACVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRNGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW", "length": 837, "header": "tr|A0A9J7JN25-1|A0A9J7JN25_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl7 PE=3 SV=1 CANONICAL=A0A9J7G9Q0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0/entry#A0A9J7JVF2-1", "sequence": { "sequence": "MQEFPLGSASCSLGLSAVISWPYLDCHFPVPSGPQLLRDPPGEGDILPFAPPSSSGSTLSFLMDFQEKDTPSLAESTQSSKPSSTQQASELWEVVEEPRGRLGAEDIMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILQYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFQSWVAQLRAHRLAQRLDMPGATHRKAPGTQMLTAGSASALPGVGPREKVSSWLRDSDGLDRCSHALLECQGKLQELHKLLQSLESLHRIPSAPVIPTHQASVTTERPKKGKRTSRMWCTQGFSKDDTIGRVGRLHGSVPNLSRYLESRDSSGHRGLPPPDYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRELHQGSELSRVTVSEAPEGQRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASSSENEGSEEEESCASEITTSLSEEVLDLRGADRYQKGACVPGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRNGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW", "length": 899, "header": "tr|A0A9J7JVF2-1|A0A9J7JVF2_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl7 PE=3 SV=1 CANONICAL=A0A9J7G9Q0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JWX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0/entry#A0A9J7JWX8-1", "sequence": { "sequence": "MDFQEKDTPSLAESTQSSKPSSTQQASELWEVVEEPRGRLGAEDIMPERQEGHLLKKRKWPLKGWHKRYFVLEDGILQYATTRQDITKGKLHGSIDVRLSVMSINKKAQRIDLDTEDNIYHLKIKSQDLFQSWVAQLRAHRLAQRLDMPGATHRKAPGTQMLTAGSASALPGVGPREKVSSWLRDSDGLDRCSHALLECQGKLQELHKLLQSLESLHRIPSAPVIPTHQASVTTERPKKGKRTSRMWCTQGFSKDDTIGRVGRLHGSVPNLSRYLESRDSSGHRGLPPPDYAHLQRSFWALAQKVHNSLSSVLVALTTERDRLRELHQGSELSRVTVSEAPEGQRRLHSLSISSDTTADSFSSLNPEEQEALYMKGRELTPQLSQSSVLSLADSHTEFFDACEVLLSASSSENEGSEEEESCASEITTSLSEEVLDLRGADRYQKGIAVGPPRRRCLPAASGPGTDVSLWNILRNNIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRMADPCERMVYIAAFAVSAYSSTYHRAGCKPFNPVLGETYECERPDRGFRFISEQVSHHPPISACHAESENFIFWQDMKWKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNILSGQRWIEHYGEVLIRNTQDSSCHCKITFCKAKYWSSNIHEVQGAVLSRNGRVLHRLFGKWHEGLYRGPPPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRTLPSTDTRLRPDQRYLEEGNIQAAEAQKRRIEQLQRDRRRVMEENNIVHQARFFRRQTDSSGKEWWVTNHTYWRLRAEPGYGNLDGAVLW", "length": 832, "header": "tr|A0A9J7JWX8-1|A0A9J7JWX8_CRIGR Computationally mapped isoform of Oxysterol-binding protein OS=Cricetulus griseus OX=10029 GN=Osbpl7 PE=3 SV=1 CANONICAL=A0A9J7G9Q0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G997", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G997" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G997", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G997" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754782", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754782", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0" } ], "pmid": "" }, { "name": "perinuclear endoplasmic reticulum", "id": "GO:0097038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097038", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "bile acid biosynthetic process", "id": "GO:0006699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006699", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cholesterol binding", "id": "GO:0015485", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015485", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0" } ], "pmid": "" }, { "name": "sterol transfer activity", "id": "GO:0120015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120015", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 679, "end_pos": 681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 878, "end_pos": 880, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G9Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9Q0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 204, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 332, "end_pos": 334 }, { "start_pos": 679, "end_pos": 681 }, { "start_pos": 878, "end_pos": 880 } ] }, 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G9A0-1", "uniprot_ac": "A0A9J7G9A0", "uniprot_id": "A0A9J7G9A0_CRIGR", "mass": { "chemical_mass": 545160.0, "monoisotopic_mass": 545160.0 }, "refseq": { "ac": "XP_027279680", "name": "hemicentin-2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279680" }, "gene_names": [ { "name": "LOC100758433", "type": "recommended", "evidence": [ { "id": "A0A9J7G9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9A0" } ] }, { "name": "LOC100758433", "type": "synonym", "evidence": [ { "id": "XP_027279680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279680" } ] } ], "protein_names": [ { "name": "Hemicentin-2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7G9A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9A0/entry#names_and_taxonomy" } ] }, { "name": "hemicentin-2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027279680", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279680" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279680" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9A0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9A0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100758433", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9A0", "locus": {} } ], "crossref": [ { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00198", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00198", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758433", "url": "https://www.ncbi.nlm.nih.gov/gene/100758433", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758433", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758433", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9A0", "url": "https://www.orthodb.org/?gene=A0A9J7G9A0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45080:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45080:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279680", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279680", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G9A0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9A0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTPGARLLPLLVAVSTVVAVVASEEPTTALSPATGGVTLAFVFDVTGSMWDDLMQVIDGASRILERSLSSRSRVITNYALVPFHDPDIGPVTLTADPVVFQRELRELYVQGGGDCPEMSVGAIKAAVEVANPGSFIYVFSDARAKDYHKKNELLQLLQLKQSQVVFVLTGDCGNRTHPGYLAYEEIASTSSGQVFQLDKQQVTEVLKWVESAIQASKVHLLSVDHEEEGEHTWRIPFDPSLKEVTISLSGPGPEIEVRDPLGRVLQTDEGLNVLLNIPDSAKVVAFKPERPGLWAIKVYSSGRHSVRISGISNINFRAGFSMQPSLDLNHTIEWPLQGVPISVVINSTGLQAPGHLDSVELSHSSGKSLLTLPTQLLSNGSTHQLWAGPPFHTPKERFYLKVKGQDHEGNPLLRVSGVSYSGVAPGVPLVSMAPRIHGYLQQPLLVSCSVYSTLPFRLQLQRDGARLGEERHFQGSGNSSWEIPRASKAEEGMYQCIAVSRAGKGQANAKIVITDPPPQLAPGPNVTVSPGETAILSCQVLGDDVPYNLTWVRDWRALPATAGRVTQLHDLSLEVSNVTTGDGGQYQCVASNVNGVTRASTWLLVREAPQVSINARSQRFSQGVEVRVSCSASGYPTPHISWSREGLTLPEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYTDPPSVSAVNAVVLTAVGEEAVLMCVASGVPLPRIIWYRGGLEVILAPEGSKSGTLRIPAAQERDGGLYTCRAVNELGDASAEIQLVVGHAPRLTETPQDVTVELGKSVFLTCRATGRPPPTVTWRRGDGQALEPGRGSRTGQRDSGVLVFERVAPEDQGLYVCEARNVFGKAQAEALLVVTGHAPPQIASSAFIIRVLEGQPVSLTCVILAGRPLPERRWLKAGRPLPPGGRHAIRADGSLHLDRALQEDAGRYSCVATNVAGSQHRDVELVVQVPPRIHPTATHHVTKEGVPASLPCTASGVPTPTITWTKETNILTTRGHYNVSRDGTLVIIQPSPQDAGAYVCTATNSVGFSSQEMWLSVNTKPRIKMNESQAMDAPLRVTVKAGQEVTLDCEAQGSPPPLVTWTKDTHPLLSVTNRYDLLPSGSLHLAHTQVGDNGHYECTASNPAGATSRHYTLRVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPEPQLRWFKDGMALRGEGPQGSVHFAAVQTSDAGLYRCEASSSAGTDTWNLELRVLEPPHWGADETKGLLERVAGENASLPCPAQGTPKPQVTWRRGPSSEPLSGRADVAVLDEGSLFLSSVSLADSGEYECQATNEVGSASRRAKLVVYVPPSIREEGRVTNVSGLAGQPLTLECDTNGFPAPEMVWLKDWQLIPEAGDYRLLDGARSLHFPRIQESDSGLYTCRAENQAGSAQRDFNLAVFIPPSLLGAGTAQEVLGLAGADVELECQTSGVPTPQVEWTKDGQPILPGNPHTLLQEDGQVLRIISSHLGDEGRYQCVAFSPAGQQAKDFQLSIHSPPTIWGSNETGEVTVLAGHTAQLLCEARGMPIPDIIWHKDGTLLTPSSEVVYSKGGRLLQLAKAQLSDAGLYTCQASNPAGITKKSTRLEVYVSPTIEGADGGPYLVQAVAGRPVALECVARGYPPPTISWQHEGLPLVDSNGTWLEAGGTLQLENPGEASGGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGMGQVTAIVGQPLDLPCQASGSPVPTIQWLQNGRPAEELDGVQLASQGTILRIAQVELDHSGLFACQATNEAGTSGAEVEVSVHELPSVHIIGGENLTAPFLQPVTLQCVGTGVPTPSLRWWKDGVAMATSGGRLQIEKADLRDEGVYTCVATNLAGESKKDVTLRVLVPPNIEPGPVNKAVLENASVTLECLASGVPSPDVSWFKGHQPISAQRGVTVSADGRVLHIARAQLSDAGSYRCVATNVVGSTGLQYGLRVNVPPRITLPPSLLGPVLLGTPFRLTCNATGTPSPTLIWLKDGNPVSPEGTPGLKIFPGGQVLTVASAHTSDAGSYSCVAVNAVGEDRREIVLQVHMPPSILGEELNVSVVVNESVALECQSHAMPRPVLRWQKDGRPLEPHPGIRLSADKALLEVDRAQMWDAGHYTCEALNQAGRSEKHFNLNVWVPPAFPSKEPYTLTVSEGQTARLSCDCQGVPFPKISWRKDGQPLPGERDGLEQVLAVGRLLYLGQARSSQEGTYICECSNAAGTSSQEQQLEVLVPPQVTGPWEPLTTVSVVQGGNTTLDCNATGKPLPVVTWERNGQPVRMEPGLWLQNQNRSLHVEQAQPSQAGGYSCVAENIAGRAEKRFTLSVLVPPQLTGDLDSLTNVTATLHGSLTLLCEVSGVPPPTVQWFREGQPISPGEDTYLLAGGWMLKMTPAREQDRGLYSCLASNEAGEAQRKFSVEVLVPPRIENEDLEEVIKVPEGQTAQLVCNATGHPPPKITWFKDGQSLAVGDTYEMSPDGTFLWVSQANLSSAGHYSCIAANAVGEKTKHAQLNVLVVPTILGAPENANEEVTVTINNPISLICEALAFPSPNITWMKDGVPFKASKNIQLLPGTHGLQILNAQKEDAGQYTCMVTNELGEATKNYHVEVLIPPSISKDDPLGEISVKEVKTKVNSTLTLECECWAVPPPSISWYKDGRPVTPSQRLHVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKMGDVDSGFELLPHEEEAQGRVTEYREIVENNPAYLYCDTNAVPPPELTWYKEGQPLSAADGVSVLQGGRILQLSLVQAEDAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTQELVEEVTVNASSAVSLQCPALGNPAPTLSWLQNGLPVSPSPRLQVLEEGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPQISGWHADKLTTTLNSSVSLTCEVHAHPSPEVTWYKDGQPLSLGQEVFFLPGTHTLRLARVQPADSGTYLCEALNAAGRDQKTVQLDVLVPPTFKRTPGSPQEAVVVRAGDKAVLSCETDSLPEPAVTWFKDQQPLALERRIQGLQGGQKLEIMDSQASDKGVYSCKVSNPAGEATQTFVLAIQMPPTFEKPETETVSQVAGRPLVLACDVSGTPAPTVTWLKDRMPVESSLVHGVVSRGGRLQLSRLQPAQAGIYTCVAENAQAEARKDFVVSVLVPPQIQNSGTAQEHNVLERQEIRLDCDAEGQPPPDIAWLKDGSPLDQHVGPHLRFYLDGSSLVLKGLKAADSGAYTCVAHNPAGEDARLHTVNVLVPPTIEQRAGDTGTLVSKTGELVTMMCPVRGSPPIHVSWLKDGLPLPLSQRTFLHSSGRTLRISQVQLADSGIFTCVAASPAGVAGRNFTVLVLVPPTLEPVEFQNDVMAVQGSEVVLPCEARGSPLPLVSWMKDGEPLLPQILEQGPGLKLEAVSIGDSGTYSCMAASEAGEARRSFRLTVMDPPHIEESGQTSELSLTPGAHLELLCEAQGIPPPNITWHKDGQALRRIENDSQAGRVLRVRNVQVDNAGLYTCLAESPAGEVEKSFRVRVQAPPNVVGPRGPRSVVGLAPGQLILECSVEAEPAPEIEWHRGGILLQADAHTQFPEQGRFLKLQALSTADAGDYSCTARNTAGSTSVAFHVEIHMAPTIQPGPNVVDIPVNRTALLPCQAHGVPTPLMSWRKDGIPLDPGSPRLEFLPEGSLRIDPVLEQDAGHYLCVASNSAGSDRQGLDLRVLEPPTIAPGPSNLTLTAHSPASLPCEAKGSPKPLVSWWKDGQKLDFRLQQDAYRLLPSNALLLAAPSPQDSAQFECVVSNEVGESRRRYQVTVHVPPTIADDQTDFTVTRMAPVVLTCHSTGSPAPAVSWSKAGTKLGARGSGYRVLPSGALEIEQALPIHAGRYTCTARNSAGMARKHMVLIVQASPVVKPLPSVVQAVESEEVLLPCEASGIPQPVVIWQKEGLSIPEGTRIRVLASGQLWITHTSPEDAGNYFCIAQNSVGSAMAKTRLVVQVPPVIENGLPDLSTTEGSNALLPCTAKGSPEPAITWEKDGQLVSGADGKFALQPSGELLVKSSESQDAGTYICTAENAVGRARRRVHLTILTLPVLTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTINDQPVTEGVSEQDGGSTLQRAAVAREDGGTYVCWAENRVGRVQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIRLDCVVRGDPAPDIRWTKDSLPLPVSRLYLQLQNGSLTILRTKMDDAGRYQCLATNEMGAVKKVVTLVLQSAPVFLVEPRDLTVRLGEDVELRCQATGEPVPTIEWLRAGRPLQADRRLRTLPDGSLWLGHVEAGDAGAYECVAHNLLGSATAQALLAVRGEPRGSRGSMIGVINGQEFGMATLNTSVQQEGSSGVATIWSSISHVPASVGPLMRVLVVTIAPIYWALARESGGALNGYSLTGGSFQQESHMEFSTGELLTMTQMARGLDPDGLLLLEVTINGMIPESLADADLHMQDFQENYVQTGPGQLFVGSTQHFRHDSLPASLRCNHSIQYDKARGPQPQLVQHLRASSISSTFDPEAEALRFQLTTALQAEENEVGCPEGFEMDTQGTFCVDRNECSAGPSPCSHTCRNAPGHFSCSCPTGFTLARDHRNCRDVDECVGDTHLCQEGQRCVNLLGTYNCLPDCRPGFRVTADGNSCEDVDECLEQLDECHYNQLCENTAGSHHCSCPRGYRQQGHGLPCLDINECLQLPTPCVYQCHNLQGSFHCLCPPGQTLLRDGRTCAPLERNNQNVTTVSLRNPFVPWLRSRIPRPRGSYHAWVSLQPGSGALSSMGRAWCPPGFIRQNGMCTDLDECRVRSLCQHACQNTEGSYYCLCPSGYRLLPSGKNCQDIDECEEDGIECGPGQMCFNTRGSYQCVDTPCPTAYRQGSSPGTCFRRCSQDCSASGPSTLQYRLLPLPLGVRAHHDVARLAAFSEAGVPANRTELTVLEHDPRSPFALRQLRAGQGAVYTRRALTRAGLYRMTVRAAAPRHQSIYVLLIAVSPYPY", "length": 5074, "header": "tr|A0A9J7G9A0-1|A0A9J7G9A0_CRIGR Isoform 1 of Hemicentin-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100758433 PE=4 SV=1 CANONICAL=A0A9J7G9A0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G9A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9A0/entry#A0A9J7G9A0-1", "sequence": { "sequence": "MTPGARLLPLLVAVSTVVAVVASEEPTTALSPATGGVTLAFVFDVTGSMWDDLMQVIDGASRILERSLSSRSRVITNYALVPFHDPDIGPVTLTADPVVFQRELRELYVQGGGDCPEMSVGAIKAAVEVANPGSFIYVFSDARAKDYHKKNELLQLLQLKQSQVVFVLTGDCGNRTHPGYLAYEEIASTSSGQVFQLDKQQVTEVLKWVESAIQASKVHLLSVDHEEEGEHTWRIPFDPSLKEVTISLSGPGPEIEVRDPLGRVLQTDEGLNVLLNIPDSAKVVAFKPERPGLWAIKVYSSGRHSVRISGISNINFRAGFSMQPSLDLNHTIEWPLQGVPISVVINSTGLQAPGHLDSVELSHSSGKSLLTLPTQLLSNGSTHQLWAGPPFHTPKERFYLKVKGQDHEGNPLLRVSGVSYSGVAPGVPLVSMAPRIHGYLQQPLLVSCSVYSTLPFRLQLQRDGARLGEERHFQGSGNSSWEIPRASKAEEGMYQCIAVSRAGKGQANAKIVITDPPPQLAPGPNVTVSPGETAILSCQVLGDDVPYNLTWVRDWRALPATAGRVTQLHDLSLEVSNVTTGDGGQYQCVASNVNGVTRASTWLLVREAPQVSINARSQRFSQGVEVRVSCSASGYPTPHISWSREGLTLPEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAANEVGTDEETVTLYYTDPPSVSAVNAVVLTAVGEEAVLMCVASGVPLPRIIWYRGGLEVILAPEGSKSGTLRIPAAQERDGGLYTCRAVNELGDASAEIQLVVGHAPRLTETPQDVTVELGKSVFLTCRATGRPPPTVTWRRGDGQALEPGRGSRTGQRDSGVLVFERVAPEDQGLYVCEARNVFGKAQAEALLVVTGHAPPQIASSAFIIRVLEGQPVSLTCVILAGRPLPERRWLKAGRPLPPGGRHAIRADGSLHLDRALQEDAGRYSCVATNVAGSQHRDVELVVQVPPRIHPTATHHVTKEGVPASLPCTASGVPTPTITWTKETNILTTRGHYNVSRDGTLVIIQPSPQDAGAYVCTATNSVGFSSQEMWLSVNTKPRIKMNESQAMDAPLRVTVKAGQEVTLDCEAQGSPPPLVTWTKDTHPLLSVTNRYDLLPSGSLHLAHTQVGDNGHYECTASNPAGATSRHYTLRVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPEPQLRWFKDGMALRGEGPQGSVHFAAVQTSDAGLYRCEASSSAGTDTWNLELRVLEPPHWGADETKGLLERVAGENASLPCPAQGTPKPQVTWRRGPSSEPLSGRADVAVLDEGSLFLSSVSLADSGEYECQATNEVGSASRRAKLVVYVPPSIREEGRVTNVSGLAGQPLTLECDTNGFPAPEMVWLKDWQLIPEAGDYRLLDGARSLHFPRIQESDSGLYTCRAENQAGSAQRDFNLAVFIPPSLLGAGTAQEVLGLAGADVELECQTSGVPTPQVEWTKDGQPILPGNPHTLLQEDGQVLRIISSHLGDEGRYQCVAFSPAGQQAKDFQLSIHSPPTIWGSNETGEVTVLAGHTAQLLCEARGMPIPDIIWHKDGTLLTPSSEVVYSKGGRLLQLAKAQLSDAGLYTCQASNPAGITKKSTRLEVYVSPTIEGADGGPYLVQAVAGRPVALECVARGYPPPTISWQHEGLPLVDSNGTWLEAGGTLQLENPGEASGGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGMGQVTAIVGQPLDLPCQASGSPVPTIQWLQNGRPAEELDGVQLASQGTILRIAQVELDHSGLFACQATNEAGTSGAEVEVSVHELPSVHIIGGENLTAPFLQPVTLQCVGTGVPTPSLRWWKDGVAMATSGGRLQIEKADLRDEGVYTCVATNLAGESKKDVTLRVLVPPNIEPGPVNKAVLENASVTLECLASGVPSPDVSWFKGHQPISAQRGVTVSADGRVLHIARAQLSDAGSYRCVATNVVGSTGLQYGLRVNVPPRITLPPSLLGPVLLGTPFRLTCNATGTPSPTLIWLKDGNPVSPEGTPGLKIFPGGQVLTVASAHTSDAGSYSCVAVNAVGEDRREIVLQVHMPPSILGEELNVSVVVNESVALECQSHAMPRPVLRWQKDGRPLEPHPGIRLSADKALLEVDRAQMWDAGHYTCEALNQAGRSEKHFNLNVWVPPAFPSKEPYTLTVSEGQTARLSCDCQGVPFPKISWRKDGQPLPGERDGLEQVLAVGRLLYLGQARSSQEGTYICECSNAAGTSSQEQQLEVLVPPQVTGPWEPLTTVSVVQGGNTTLDCNATGKPLPVVTWERNGQPVRMEPGLWLQNQNRSLHVEQAQPSQAGGYSCVAENIAGRAEKRFTLSVLVPPQLTGDLDSLTNVTATLHGSLTLLCEVSGVPPPTVQWFREGQPISPGEDTYLLAGGWMLKMTPAREQDRGLYSCLASNEAGEAQRKFSVEVLVPPRIENEDLEEVIKVPEGQTAQLVCNATGHPPPKITWFKDGQSLAVGDTYEMSPDGTFLWVSQANLSSAGHYSCIAANAVGEKTKHAQLNVLVVPTILGAPENANEEVTVTINNPISLICEALAFPSPNITWMKDGVPFKASKNIQLLPGTHGLQILNAQKEDAGQYTCMVTNELGEATKNYHVEVLIPPSISKDDPLGEISVKEVKTKVNSTLTLECECWAVPPPSISWYKDGRPVTPSQRLHVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKMGDVDSGFELLPHEEEAQGRVTEYREIVENNPAYLYCDTNAVPPPELTWYKEGQPLSAADGVSVLQGGRILQLSLVQAEDAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTQELVEEVTVNASSAVSLQCPALGNPAPTLSWLQNGLPVSPSPRLQVLEEGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPQISGWHADKLTTTLNSSVSLTCEVHAHPSPEVTWYKDGQPLSLGQEVFFLPGTHTLRLARVQPADSGTYLCEALNAAGRDQKTVQLDVLVPPTFKRTPGSPQEAVVVRAGDKAVLSCETDSLPEPAVTWFKDQQPLALERRIQGLQGGQKLEIMDSQASDKGVYSCKVSNPAGEATQTFVLAIQMPPTFEKPETETVSQVAGRPLVLACDVSGTPAPTVTWLKDRMPVESSLVHGVVSRGGRLQLSRLQPAQAGIYTCVAENAQAEARKDFVVSVLVPPQIQNSGTAQEHNVLERQEIRLDCDAEGQPPPDIAWLKDGSPLDQHVGPHLRFYLDGSSLVLKGLKAADSGAYTCVAHNPAGEDARLHTVNVLVPPTIEQRAGDTGTLVSKTGELVTMMCPVRGSPPIHVSWLKDGLPLPLSQRTFLHSSGRTLRISQVQLADSGIFTCVAASPAGVAGRNFTVLVLVPPTLEPVEFQNDVMAVQGSEVVLPCEARGSPLPLVSWMKDGEPLLPQILEQGPGLKLEAVSIGDSGTYSCMAASEAGEARRSFRLTVMDPPHIEESGQTSELSLTPGAHLELLCEAQGIPPPNITWHKDGQALRRIENDSQAGRVLRVRNVQVDNAGLYTCLAESPAGEVEKSFRVRVQAPPNVVGPRGPRSVVGLAPGQLILECSVEAEPAPEIEWHRGGILLQADAHTQFPEQGRFLKLQALSTADAGDYSCTARNTAGSTSVAFHVEIHMAPTIQPGPNVVDIPVNRTALLPCQAHGVPTPLMSWRKDGIPLDPGSPRLEFLPEGSLRIDPVLEQDAGHYLCVASNSAGSDRQGLDLRVLEPPTIAPGPSNLTLTAHSPASLPCEAKGSPKPLVSWWKDGQKLDFRLQQDAYRLLPSNALLLAAPSPQDSAQFECVVSNEVGESRRRYQVTVHVPPTIADDQTDFTVTRMAPVVLTCHSTGSPAPAVSWSKAGTKLGARGSGYRVLPSGALEIEQALPIHAGRYTCTARNSAGMARKHMVLIVQASPVVKPLPSVVQAVESEEVLLPCEASGIPQPVVIWQKEGLSIPEGTRIRVLASGQLWITHTSPEDAGNYFCIAQNSVGSAMAKTRLVVQVPPVIENGLPDLSTTEGSNALLPCTAKGSPEPAITWEKDGQLVSGADGKFALQPSGELLVKSSESQDAGTYICTAENAVGRARRRVHLTILTLPVLTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTINDQPVTEGVSEQDGGSTLQRAAVAREDGGTYVCWAENRVGRVQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIRLDCVVRGDPAPDIRWTKDSLPLPVSRLYLQLQNGSLTILRTKMDDAGRYQCLATNEMGAVKKVVTLVLQSAPVFLVEPRDLTVRLGEDVELRCQATGEPVPTIEWLRAGRPLQADRRLRTLPDGSLWLGHVEAGDAGAYECVAHNLLGSATAQALLAVRGEPRGSRGSMIGVINGQEFGMATLNTSVQQEGSSGVATIWSSISHVPASVGPLMRVLVVTIAPIYWALARESGGALNGYSLTGGSFQQESHMEFSTGELLTMTQMARGLDPDGLLLLEVTINGMIPESLADADLHMQDFQENYVQTGPGQLFVGSTQHFRHDSLPASLRCNHSIQYDKARGPQPQLVQHLRASSISSTFDPEAEALRFQLTTALQAEENEVGCPEGFEMDTQGTFCVDRNECSAGPSPCSHTCRNAPGHFSCSCPTGFTLARDHRNCRDVDECVGDTHLCQEGQRCVNLLGTYNCLPDCRPGFRVTADGNSCEDVDECLEQLDECHYNQLCENTAGSHHCSCPRGYRQQGHGLPCLDINECLQLPTPCVYQCHNLQGSFHCLCPPGQTLLRDGRTCAPLERNNQNVTTVSLRNPFVPWLRSRIPRPRGSYHAWVSLQPGSGALSSMGRAWCPPGFIRQNGMCTDLDECRVRSLCQHACQNTEGSYYCLCPSGYRLLPSGKNCQDIDECEEDGIECGPGQMCFNTRGSYQCVDTPCPTAYRQGSSPGTCFRRCSQDCSASGPSTLQYRLLPLPLGVRAHHDVARLAAFSEAGVPANRTELTVLEHDPRSPFALRQLRAGQGAVYTRRALTRAGLYRMTVRAAAPRHQSIYVLLIAVSPYPY", 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This record is derived from a genomic sequence (NW_003614338.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016833456", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833456" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pip5kl1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8", "locus": {} } ], "crossref": [ { "id": "A0A9J7G9D8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G9D8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17304", "database": "CDD", "categories": [ "Protein Classification" ] 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5-kinase-like protein 1 OS=Cricetulus griseus OX=10029 GN=Pip5kl1 PE=4 SV=1 CANONICAL=A0A9J7G9D8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JMT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8/entry#A0A9J7JMT4-1", "sequence": { "sequence": "MATKTGRTRFRLPASRASTRKARPWFRRKLRRKLSLRHPNQYPAAPPGQDQGPEDAAAAEVGPAGKHQRPPRRSGATEARKPILRHSRQRSAAPPGQDQGPQDAAAAEVGPVRKGPRSPRGLGTTRTGSSRLASRSAEVGPDSCIGASGTQPKPEKLQLGAMAAPSPGPREIPAPSLEVGSRAVVPGDRRGLLWRGLRDKHNRVGLFEINPGHELHRMTRMMQEGLWAATEVFKENPPKGPPTQKDFSEVMTQVHEEGFELCTLAGPAFARLRRYLGLTEEDYQATLGPRGPYLQFLSTSKSKASFFLSHDQRFFLKTQRRHEVQVLLAHLPRYVQHLLRHPHTLLARLLGVHSLRVAQGKKKYFIIMQSVFYPVSRISERYDIKACEQSRWVEPVPEGSPLLLVLKDLNFEGKTIRLGSQRSWFLRQLELDTTFLRDLNVLDYSLLVAFQLLHEDEKDRFSIFRTFRPRNGGSQGEGGERDHSAINAGTSLSHALCLGIYSLGHPAPIVLALYSGEGGEWSLYPLVPMGGTSPGVLWCRLGARPALDTRPPNSQL", "length": 556, "header": "tr|A0A9J7JMT4-1|A0A9J7JMT4_CRIGR Computationally mapped isoform of Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Pip5kl1 PE=4 SV=1 CANONICAL=A0A9J7G9D8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756852", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756852", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8" } ], "pmid": "" }, { "name": "1-phosphatidylinositol-4-phosphate 5-kinase activity", "id": "GO:0016308", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016308", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phosphatidylinositol phosphate biosynthetic process", "id": "GO:0046854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046854", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9D8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G9D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D8" }, { "id": "PS51455", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51455" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIPK", "eco_id": "ECO_0000259", "start_pos": 199, "end_pos": 555, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G9F8-1", "uniprot_ac": "A0A9J7G9F8", "uniprot_id": "A0A9J7G9F8_CRIGR", "mass": { "chemical_mass": 59047.0, "monoisotopic_mass": 59047.0 }, "refseq": { "ac": "XP_016818851", "name": "apoptosis inhibitor 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818851" }, "gene_names": [ { "name": "Api5", "type": "recommended", "evidence": [ { "id": "A0A9J7G9F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8" } ] }, { "name": "Api5", "type": "synonym", "evidence": [ { "id": "XP_016818851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818851" } ] } ], "protein_names": [ { "name": "Apoptosis inhibitor 5", "type": "recommended", "evidence": [ { "id": "A0A9J7G9F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8/entry#names_and_taxonomy" } ] }, { "name": "apoptosis inhibitor 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016818851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818851" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616279.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016818851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818851" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Api5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8", "locus": {} } ], "crossref": [ { "id": "A0A9J7G9F8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G9F8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100758910", "url": "https://www.ncbi.nlm.nih.gov/gene/100758910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758910", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758910", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RCIKFLA", "url": "https://omabrowser.org/oma/group/RCIKFLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N195", "url": "https://www.orthodb.org/?gene=A0A8C2N195", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G9F8", "url": "https://www.orthodb.org/?gene=A0A9J7G9F8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G9G4", "url": "https://www.orthodb.org/?gene=A0A9J7G9G4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12758", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12758", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12758:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12758:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05918", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05918", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016818851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N195", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N195", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N195-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N195-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9G4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENASNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRANEDTSSGSPPKKSPGGPKRDARQIYNPPSGKYSSNLGNFNYEQRGAFRGSRGGRGWGTRGNRSRGRLY", "length": 524, "header": "tr|A0A9J7G9F8-1|A0A9J7G9F8_CRIGR Isoform 1 of Apoptosis inhibitor 5 OS=Cricetulus griseus OX=10029 GN=Api5 PE=3 SV=1 CANONICAL=A0A9J7G9F8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N195-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8/entry#A0A8C2N195-1", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENASNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRANEDTSSGSPPKKSPGGPKRDARQIYNPPSGKYSSNLGNFNYERSLQGK", "length": 504, "header": "tr|A0A8C2N195-1|A0A8C2N195_CRIGR Computationally mapped isoform of Apoptosis inhibitor 5 OS=Cricetulus griseus OX=10029 GN=Api5 PE=3 SV=1 CANONICAL=A0A9J7G9F8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8/entry#A0A9J7G9F8-1", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENASNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRANEDTSSGSPPKKSPGGPKRDARQIYNPPSGKYSSNLGNFNYEQRGAFRGSRGGRGWGTRGNRSRGRLY", "length": 524, "header": "tr|A0A9J7G9F8-1|A0A9J7G9F8_CRIGR Isoform 1 of Apoptosis inhibitor 5 OS=Cricetulus griseus OX=10029 GN=Api5 PE=3 SV=1 CANONICAL=A0A9J7G9F8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8/entry#A0A9J7G9G4-1", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENASNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRANEDTSSGSPPKKSPGGPKRDARQIYNPPSGKYSSNLGNFNYGERFRLGTSSPRD", "length": 510, "header": "tr|A0A9J7G9G4-1|A0A9J7G9G4_CRIGR Computationally mapped isoform of Apoptosis inhibitor 5 OS=Cricetulus griseus OX=10029 GN=Api5 PE=3 SV=1 CANONICAL=A0A9J7G9F8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758910", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758910", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B1WC49-1", "protein_name": "Apoptosis inhibitor 5", "gene_name": "Api5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRTSEDTSSGSPPKKSPGGPKRDARQIYNPPSGKYSSNLGNFNYEQRGAFRGSRGGRGWGTRGNRSRGRLY", "length": 524 }, "evidence": [ { "id": "A0A9J7G9F8", "url": "https://omabrowser.org/oma/group/A0A9J7G9F8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O35841-1", "protein_name": "Apoptosis inhibitor 5", "gene_name": "Api5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQAFSPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLSTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRTSEDTSSGSPPKKSPGGPKRDARQIYNPPSGKYSSNLSNFNYERSLQGK", "length": 504 }, "evidence": [ { "id": "A0A9J7G9F8", "url": "https://omabrowser.org/oma/group/A0A9J7G9F8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54CL0-1", "protein_name": "Apoptosis inhibitor 5 homolog", "gene_name": "api5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METTTTTTTAAATKGTNDAMETSSSTTATPTTATVVPQVVRNDEYINTFYDIANKLDTNPSFPDDDKLFSKIIELSSKTKQTKKLSPQFISKYFKRFPTLQEKAIDCLIDLFDSSDEDVIMRVNALKAIPTICRDNPDHIAKLVDILSQLLNTDSKVEAEHTKNSLIELYKLNSVTTLNSFLTFLESEESSMEDQPASSTLLSFLKESIIPLVRTEYSKSSIETQTFFRVRILKLIAKCTSTTELDLLFQLLECFTQYKVQETITDLETNVLPVIESQSLDTIRKKLINFTKILLFKSKKPHTEINSNKLFDLYLNKIFPKVNELDETNKTELVSVFSQVTPHMTQEISMQFLEPVYNLFKATVPSKTTTPVADVDLQFTIVEALLFALSSIGSKSTSSLCKLCGFKLVTGQPSDMNADPVKYEDFLGRHRFLDEKCRETLGKAKKAIPNLGNPKDKAQLKLAQKTLLSTQNILTIMQNLLKSPPVTNINNLVISSTIFKGKQNLIHNVSPVFKPQQHQHQHQQQQVQQKQYQKYQAQQQQQQNIPIQRNQQQQQQQKSNRYQPYVTPGRRHQDLDKPKQDGVEVHYYSEKHNKPSSFKGRGPKSY", "length": 606 }, "evidence": [ { "id": "A0A9J7G9F8", "url": "https://omabrowser.org/oma/group/A0A9J7G9F8/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5ZMW3-1", "protein_name": "Apoptosis inhibitor 5", "gene_name": "API5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPTVEELYRNYGILADATETAGQHKDAYQVILDGVKGGAKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGDNLPRVADILTQLLQSDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPEEVLTKEVEEFILAESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTKFVTYFCEHVLPNLSALTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLESNLKKLFDKLLEYMPLPPEEAENGENAGGEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKADANQKRTSEDTTSSSPPKKASAGPKRDARQIYNPPSGKYSSNLGSFSYEQRGGFRGGRGRGWGGRGNRSRGRIY", "length": 523 }, "evidence": [ { "id": "A0A9J7G9F8", "url": "https://omabrowser.org/oma/group/A0A9J7G9F8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9BZZ5-4", "protein_name": "Apoptosis inhibitor 5", "gene_name": "API5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLGTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRASEDTTSGSPPKKSSAGPKRDARQIYNPPSGKYSSNLGNFNYEQRGAFRGSRGGRGWGTRGNRSRGRLY", "length": 524 }, "evidence": [ { "id": "A0A9J7G9F8", "url": "https://omabrowser.org/oma/group/A0A9J7G9F8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V431-1", "protein_name": "Apoptosis inhibitor 5 homolog", "gene_name": "cass", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDNIERLYKCYEILSEAGDKISEHVDEYKEILKAVKGTSKEKRLASQFIGNFFKHFPDLADTAIDAQFDLCEDDDTQIRRQAIKDLPKLCQGNADATIRVGDTLAQLLILDDPTELQQVNNSLLAIIKLDTKSSIAGLFQQISTGDETTRERCLKFIATKLLTMGPTVITKEIEDYIVEEIKKALQDVTADEFHLCMTILGATKLGSTITGHAELVKLATEQAELNNTDADIIAVDDEVVERFIQCASAAAPYFSKTIKSTAFVAHVCDKLLPIKTWNMIATAVSQDQIQLRLLKVFAEMITNTDKLDNASERINAVYNVLLEYMPLPKLSDEDLGDTPPSFQFSHAECLLYALHTLGKNHPNSLSFVEDAEKLKDFRARLQYLARGTQGYIKKLEESLKGKTGEELKTEENQLKQTALKTTSNINILIRDLFHSPPIFKHDIVLSWIVPKNNKLGKRHAPITFGEKAAANGKDKDQEPEKKSRPSNDQKFYSPPSGKYSNKVNQSYGNNNRTRQRGGGGGGGSGGGYRNRRFNKY", "length": 536 }, "evidence": [ { "id": "A0A9J7G9F8", "url": "https://omabrowser.org/oma/group/A0A9J7G9F8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "R4GDP5-1", "protein_name": "Apoptosis inhibitor 5", "gene_name": "api5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAATVEELYRNYGILADAKEDLSTHKDAYQVILDGVKGGAKEKRLAAQFIPKFFSSFPELADAAINAQLDLCEDEDVSIRRQAIKELPRFASGENLPRVADILTQLLQTDDSAEFNQVNTALISIFKIDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTMPEDIMTKEVEDYIFVETKKVLEDVTGEEFVLLMRILSGLKSMQTVSGRQQLVELVVEQAFLEQALNPADTDSVDRLLQCTRQALPLFSKNVHSTRFVTYFCEFVLPNLSQLTSPVAELDIQLEVLKLLAEMSPYCGDMDKLEVNLNMLFEKLLEFMPLPPEEENGENAANEEPKLQFSYVECLLFSFHQLGKKLPDFLIDKVSAEKLKDFKIRLQYFARGLQVYIRQLRVALQGKTGDALKTDENKIKVVALKITNNINVLIKDLFHNPPSYKSTVTLSWKPVQKTEAAAAIGQKRRSGEDIGATATTKKHPTNLPRRDARQIYNPPSGKYSASIGNFSYEQRGGFRGGRGRGFGGRGNRSRGRIY", "length": 529 }, "evidence": [ { "id": "A0A9J7G9F8", "url": "https://omabrowser.org/oma/group/A0A9J7G9F8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9F8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9F8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 269, "end_pos": 271 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 517, "end_pos": 519 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G9G0-1", "uniprot_ac": "A0A9J7G9G0", "uniprot_id": "A0A9J7G9G0_CRIGR", "mass": { "chemical_mass": 64527.0, "monoisotopic_mass": 64527.0 }, "refseq": { "ac": "XP_027276422", "name": "protein phosphatase 1 regulatory subunit 15A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276422" }, "gene_names": [ { "name": "Ppp1r15a", "type": "recommended", "evidence": [ { "id": "A0A9J7G9G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ] }, { "name": "Ppp1r15a", "type": "synonym", "evidence": [ { "id": "XP_027276422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276422" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 15A", "type": "recommended", "evidence": [ { "id": "A0A9J7G9G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0/entry#names_and_taxonomy" } ] }, { "name": "Growth arrest and DNA damage-inducible protein GADD34", "type": "synonym", "evidence": [ { "id": "A0A9J7G9G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 15A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027276422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276422" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276422", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276422" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppp1r15a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0", "locus": {} } ], "crossref": [ { "id": "A0A9J7G9G0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G9G0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100757625", "url": "https://www.ncbi.nlm.nih.gov/gene/100757625", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757625", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757625", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9G0", "url": "https://www.orthodb.org/?gene=A0A9J7G9G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16489", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16489", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16489:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16489:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10488", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10488", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276422", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276422", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HXJ9", "url": "https://www.uniprot.org/uniprotkb/A0A061HXJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HXJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HXJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPSPRPQHILLWRDAHSFHLLSPLMGFLSRAWSRLRVPEAPEPWPAETVTGADQIEADAHPAPPLVPENHPPQGEAEESGTPEEGKAAQGPCLDVQANSSPPETLGLSDDDKQGQDGPREQGRAHTAGLPILLSPGLQSADKSLGEVVAGEEGVTELAYPTSHWEGCPSEEEEDGETVKKAFRASADSPGHKSSTSVYCPGEAEHQATEEKQTENKADPPSSPSGSHSRAWEYCSKQEGEADPEPHRAGKYQLCQNAEAEEEEEAKVSSLSVSSGNAFLKAWVYRPGEDTEDDDDSDWGSAEEEGKALSSPTSPEHDFLKAWVYRPGEDTEDDDDSDWGSAEEEGKALSSPTSPEHDFLKAWVYRPGEDTEDDQDSDWGSAEKDGLAQTFATPHTSAFLKTWVCCPGEDTEDDDCEVVVPEDSEAADPDKSPSHEAQGCLPGEQTEGLVEAEHSLFQVAFYLPGEKPAPPWTAPKLPLRLQRRLTLLRTPTQDQDPETPLRARKVHFSENVTVHFLAVWAGPAQAARRGPWEQLARDRSRFARRIAQAEEKLGPYLTPAFRARAWARLGNPSLPLALEPICDHTFFPSQ", "length": 590, "header": "tr|A0A9J7G9G0-1|A0A9J7G9G0_CRIGR Isoform 1 of Protein phosphatase 1 regulatory subunit 15A OS=Cricetulus griseus OX=10029 GN=Ppp1r15a PE=3 SV=1 CANONICAL=A0A9J7G9G0-1" }, "isoforms": [ { "isoform_ac": "A0A061HXJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0/entry#A0A061HXJ9-1", "sequence": { "sequence": "MAPSPRPQHILLWRDAHSFHLLSPLMGFLSRAWSRLRVPEAPEPWPAETVTGADQIEADAHPAPPLVPENHPPQGEAEESGTPEEGKAAQGPCLDVQANSSPPETLGLSDDDKQGQDGPREQGRAHTAGLPILLSPGLQSADKSLGEVVAGEEGVTELAYPTSHWEGCPSEEEEDGETVKKAFRASADSPGHKSSTSVYCPGEAEHQATEEKQTENKADPPSSPSGSHSRAWEYCSKQEGEADPEPHRAGKYQLCQNAEAEEEEEAKVSSLSVSSGNAFLKAWVYRPGEDTEDDDDSDWGSAEEEGKALSSPTSPEHDFLKAWVYRPGEDTEDDQDSDWGSAEKDGLAQTFATPHTSAFLKTWVCCPGEDTEDDDCEVVVPEDSEAADPDKSPSHEAQGCLPGEQTEGLVEAEHSLFQVAFYLPGEKPAPPWTAPKLPLRLQRRLTLLRTPTQDQDPETPLRARKVHFSENVTVHFLAVWAGPAQAARRGPWEQLARDRSRFARRIAQAEEKLGPYLTPAFRARAWARLGNPSLPLALEPICDHTFFPSQ", "length": 550, "header": "tr|A0A061HXJ9-1|A0A061HXJ9_CRIGR Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 15A OS=Cricetulus griseus OX=10029 GN=Ppp1r15a PE=3 SV=1 CANONICAL=A0A9J7G9G0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0/entry#A0A9J7G9G0-1", "sequence": { "sequence": "MAPSPRPQHILLWRDAHSFHLLSPLMGFLSRAWSRLRVPEAPEPWPAETVTGADQIEADAHPAPPLVPENHPPQGEAEESGTPEEGKAAQGPCLDVQANSSPPETLGLSDDDKQGQDGPREQGRAHTAGLPILLSPGLQSADKSLGEVVAGEEGVTELAYPTSHWEGCPSEEEEDGETVKKAFRASADSPGHKSSTSVYCPGEAEHQATEEKQTENKADPPSSPSGSHSRAWEYCSKQEGEADPEPHRAGKYQLCQNAEAEEEEEAKVSSLSVSSGNAFLKAWVYRPGEDTEDDDDSDWGSAEEEGKALSSPTSPEHDFLKAWVYRPGEDTEDDDDSDWGSAEEEGKALSSPTSPEHDFLKAWVYRPGEDTEDDQDSDWGSAEKDGLAQTFATPHTSAFLKTWVCCPGEDTEDDDCEVVVPEDSEAADPDKSPSHEAQGCLPGEQTEGLVEAEHSLFQVAFYLPGEKPAPPWTAPKLPLRLQRRLTLLRTPTQDQDPETPLRARKVHFSENVTVHFLAVWAGPAQAARRGPWEQLARDRSRFARRIAQAEEKLGPYLTPAFRARAWARLGNPSLPLALEPICDHTFFPSQ", "length": 590, "header": "tr|A0A9J7G9G0-1|A0A9J7G9G0_CRIGR Isoform 1 of Protein phosphatase 1 regulatory subunit 15A OS=Cricetulus griseus OX=10029 GN=Ppp1r15a PE=3 SV=1 CANONICAL=A0A9J7G9G0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757625", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757625", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "protein phosphatase type 1 complex", "id": "GO:0000164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000164", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ], "pmid": "" }, { "name": "response to endoplasmic reticulum stress", "id": "GO:0034976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034976", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9G0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G9G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9G0" }, { "id": "PF10488", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10488" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein phosphatase 1 regulatory subunit 15A/B C-terminal", "eco_id": "ECO_0000259", "start_pos": 499, "end_pos": 569, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 511, "end_pos": 513 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G9I2-1", "uniprot_ac": "A0A9J7G9I2", "uniprot_id": "A0A9J7G9I2_CRIGR", "mass": { "chemical_mass": 66369.0, "monoisotopic_mass": 66369.0 }, "refseq": { "ac": "XP_027278287", "name": "cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278287" }, "gene_names": [ { "name": "Creb3l1", "type": "recommended", "evidence": [ { "id": "A0A9J7G9I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I2" } ] }, { "name": "Creb3l1", "type": "synonym", "evidence": [ { "id": "XP_027278287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278287" } ] } ], "protein_names": [ { "name": "Cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7G9I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I2/entry#names_and_taxonomy" } ] }, { "name": "cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027278287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278287" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278287" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Creb3l1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I2", "locus": {} } ], "crossref": [ { "id": "A0A9J7G9I2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G9I2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14689", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14689", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762192", "url": "https://www.ncbi.nlm.nih.gov/gene/100762192", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762192", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762192", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LUP4", "url": "https://www.orthodb.org/?gene=A0A8C2LUP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G9I2", "url": "https://www.orthodb.org/?gene=A0A9J7G9I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46004", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46004", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46004:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46004:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278287", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LUP4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LUP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9I2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAVLEPFPADRLFPGSSFLDLGDLNESDFLNNAHFPEHLDHFVENMEDFSNDLFSSFFDDPVLDEKSPLLDMELDSPAPGIQAEHSYSLSGDSAPQSPLVPIKMEDTTQDVERGAWALGHKLCSIMVKQEQSPELPVDPLAASSAMAAAAAAMATPPLLGVSPISRLPIPHQAPGEMTQLPVIKAEPPEVSQFLKVTPEDLVQMPPTPPSSHGSDSDGSQSPRSLPPSSPVRPMARSSTAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETYTSENNELWKKVETLENANRTLLQQLQKLQTLVTSKISRPYKMAATQTGTCLMVAALCFVLVLGSLVPCLPAFSSGSKTVKEDPIAADSVYTASQMPSRSLLFYDDGTGLWEDGRGALLPVEPPEGWELKPGGPVEPRPQDHLRHDYMDSTHETTKYLSETWPEDANDNGTSPNFSHPKEWFHDRPLRDPGHRTDTLAPRRGILLLTDPDPAPTPVLEPSAPGERVFLLPSHPGPCCDWSPSMSPGIWTAPLGQPLCSHFFPQSSVLSNKPLTGPLLFPFP", "length": 606, "header": "tr|A0A9J7G9I2-1|A0A9J7G9I2_CRIGR Isoform 1 of Cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Creb3l1 PE=3 SV=1 CANONICAL=A0A9J7G9I2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LUP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I2/entry#A0A8C2LUP4-1", "sequence": { "sequence": "MDAVLEPFPADRLFPGSSFLDLGDLNESDFLNNAHFPEHLDHFVENMEDFSNDLFSSFFDDPVLDEKSPLLDMELDSPAPGIQAEHSYSLSGDSAPQSPLVPIKMEDTTQDVERGAWALGHKLCSIMVKQEQSPELPVDPLAASSAMAAAAAAMATPPLLGVSPISRLPIPHQAPGEMTQLPVIKAEPPEVSQFLKVTPEDLVQMPPTPPSSHGSDSDGSQSPRSLPPSSPVRPMARSSTAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETYTSENNELWKKVETLENANRTLLQQLQKLQTLVTSKISRPYKMAATQTGTCLMVAALCFVLVLGSLVPCLPAFSSGSKTVKEDPIAADSVYTASQMPSRSLLFYDDGTGLWEDGRGALLPVEPPEGWELKPGGPVEPRPQDHLRHDYMDSTHETTKYLSETWPEDANDNGTSPNFSHPKEWFHDRDLGPNTTIKLS", "length": 521, "header": "tr|A0A8C2LUP4-1|A0A8C2LUP4_CRIGR Computationally mapped isoform of Cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Creb3l1 PE=3 SV=1 CANONICAL=A0A9J7G9I2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I2/entry#A0A9J7G9I2-1", "sequence": { "sequence": "MDAVLEPFPADRLFPGSSFLDLGDLNESDFLNNAHFPEHLDHFVENMEDFSNDLFSSFFDDPVLDEKSPLLDMELDSPAPGIQAEHSYSLSGDSAPQSPLVPIKMEDTTQDVERGAWALGHKLCSIMVKQEQSPELPVDPLAASSAMAAAAAAMATPPLLGVSPISRLPIPHQAPGEMTQLPVIKAEPPEVSQFLKVTPEDLVQMPPTPPSSHGSDSDGSQSPRSLPPSSPVRPMARSSTAISTSPLLTAPHKLQGTSGPLLLTEEEKRTLIAEGYPIPTKLPLTKAEEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETYTSENNELWKKVETLENANRTLLQQLQKLQTLVTSKISRPYKMAATQTGTCLMVAALCFVLVLGSLVPCLPAFSSGSKTVKEDPIAADSVYTASQMPSRSLLFYDDGTGLWEDGRGALLPVEPPEGWELKPGGPVEPRPQDHLRHDYMDSTHETTKYLSETWPEDANDNGTSPNFSHPKEWFHDRPLRDPGHRTDTLAPRRGILLLTDPDPAPTPVLEPSAPGERVFLLPSHPGPCCDWSPSMSPGIWTAPLGQPLCSHFFPQSSVLSNKPLTGPLLFPFP", "length": 606, "header": "tr|A0A9J7G9I2-1|A0A9J7G9I2_CRIGR Isoform 1 of Cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Creb3l1 PE=3 SV=1 CANONICAL=A0A9J7G9I2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 208, "start_aa": "Thr", "end_pos": 208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr208", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 539, "start_aa": "Thr", "end_pos": 539, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr539", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279858" } ] }, { "annotation": "Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757399", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757399", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDLWPGM", "url": "https://omabrowser.org/oma/group/MDLWPGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G9I4", "url": "https://www.orthodb.org/?gene=A0A9J7G9I4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279858", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G9I4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2U3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2U3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVB8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVB8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQALRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEDEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLDRATGEHASVHEYPGELGQPPGLYPSNHPPGRAGTLRALSRQDTFDADTPGSRNSAYTEPGDSCVDMETDPSEGPGPGDPAGGGTPPARQGSWEDEEDYEEEMTDNRNKGRNKGRYCAEGGGPVLGRNKNELEGWGQGVYIR", "length": 642, "header": "tr|A0A9J7G9I4-1|A0A9J7G9I4_CRIGR Isoform 1 of Voltage-dependent L-type calcium channel subunit beta-1 OS=Cricetulus griseus OX=10029 GN=Cacnb1 PE=3 SV=1 CANONICAL=A0A9J7G9I4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G9I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4/entry#A0A9J7G9I4-1", "sequence": { "sequence": "MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQALRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEDEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLDRATGEHASVHEYPGELGQPPGLYPSNHPPGRAGTLRALSRQDTFDADTPGSRNSAYTEPGDSCVDMETDPSEGPGPGDPAGGGTPPARQGSWEDEEDYEEEMTDNRNKGRNKGRYCAEGGGPVLGRNKNELEGWGQGVYIR", "length": 642, "header": "tr|A0A9J7G9I4-1|A0A9J7G9I4_CRIGR Isoform 1 of Voltage-dependent L-type calcium channel subunit beta-1 OS=Cricetulus griseus OX=10029 GN=Cacnb1 PE=3 SV=1 CANONICAL=A0A9J7G9I4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4/entry#A0A9J7H1N4-1", "sequence": { "sequence": "MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQALRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQVQVLTSLRRNLSFWGGLEASPQGGDAVAQPQEHAM", "length": 471, "header": "tr|A0A9J7H1N4-1|A0A9J7H1N4_CRIGR Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-1 OS=Cricetulus griseus OX=10029 GN=Cacnb1 PE=3 SV=1 CANONICAL=A0A9J7G9I4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4/entry#A0A9J7H2U3-1", "sequence": { "sequence": "MEAPSRTLVVGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQALRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEDEEAELGEQSGSAKTSVSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQVQVLTSLRRNLSFWGGLEASPQGGDAVAQPQEHAM", "length": 477, "header": "tr|A0A9J7H2U3-1|A0A9J7H2U3_CRIGR Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-1 OS=Cricetulus griseus OX=10029 GN=Cacnb1 PE=3 SV=1 CANONICAL=A0A9J7G9I4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4/entry#A0A9J7JVB8-1", "sequence": { "sequence": "MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQALRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLDRATGEHASVHEYPGELGQPPGLYPSNHPPGRAGTLRALSRQDTFDADTPGSRNSAYTEPGDSCVDMETDPSEGPGPGDPAGGGTPPARQGSWEDEEDYEEEMTDNRNKGRNKGRYCAEGGGPVLGRNKNELEGWGQGVYIR", "length": 597, "header": "tr|A0A9J7JVB8-1|A0A9J7JVB8_CRIGR Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-1 OS=Cricetulus griseus OX=10029 GN=Cacnb1 PE=3 SV=1 CANONICAL=A0A9J7G9I4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 463, "start_aa": "Thr", "end_pos": 463, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr463", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 585, "start_aa": "Thr", "end_pos": 585, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr585", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9I4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9I4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757399", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757399", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P54283-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-1", "gene_name": "Cacnb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSRTPPNPLLNRTMATAALAVSPAPVSNLQGPYLVSGDQPLDRATGEHASVHEYPGELGQPPGLYPSNHPPGRAGTLWALSRQDTFDADTPGSRNSVYTEPGDSCVDMETDPSEGPGPGDPAGGGTPPARQGSWEEEEDYEEEMTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGQGVYIR", "length": 597 }, "evidence": [ { "id": "A0A9J7G9I4", "url": "https://omabrowser.org/oma/group/A0A9J7G9I4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02641-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-1", "gene_name": "CACNB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASMHEYPGELGQPPGLYPSSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTELGDSCVDMETDPSEGPGLGDPAGGGTPPARQGSWEDEEEDYEEELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR", "length": 598 }, "evidence": [ { "id": "A0A9J7G9I4", "url": "https://omabrowser.org/oma/group/A0A9J7G9I4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R3Z5-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-1", "gene_name": "Cacnb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLDRATGEHASVHEYPGELGQPPGLYPSNHPLGRAGTLRALSRQDTFDADTPGSRNSAYTEPGDSCVDMETDPSEGPGPGDPAGGGTPPARQGSWEDEEDYEEEMTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGQGVYTR", "length": 597 }, "evidence": [ { "id": "A0A9J7G9I4", "url": "https://omabrowser.org/oma/group/A0A9J7G9I4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "sarcolemma", "id": "GO:0042383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042383", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9I4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4" } ], "pmid": "" }, { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9I4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9I4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G9I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9I4" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 169, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 463, 585 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 470, "end_pos": 472 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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Promotes cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8#function" }, { "database": "UniProtKB", "id": "RU369088", "url": "https://www.uniprot.org/uniprotkb/RU369088#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptov1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8", "locus": {} } ], "crossref": [ { "id": "100767703", "url": "https://www.ncbi.nlm.nih.gov/gene/100767703", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038196", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038196", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767703", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767703", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9K8", "url": "https://www.orthodb.org/?gene=A0A9J7G9K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12433", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12433", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12433:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12433:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276530", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276530", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G9K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRPRRAPHRSGAXGPLGGRGRPPRPLVVRAVRSRSWPSGPRGPQPPRIRARSAPPMEGARVFGALGPIGPSSPGLSVGGLAVNEHRLSNKLLAWSGVLEWQEKRRPFSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNAIRQVITTRKQAVGPGGVHSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTDQWPRKLFMQLIPQQLLTTLVPLFRNSRLVQFHFTKDMETLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQSNFVNGIRRVIANQQQVLQRSLEQEQQQRGMGG", "length": 416, "header": "tr|A0A9J7G9K8-1|A0A9J7G9K8_CRIGR Isoform 1 of Prostate tumor-overexpressed gene 1 protein OS=Cricetulus griseus OX=10029 GN=Ptov1 PE=3 SV=1 CANONICAL=A0A9J7G9K8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G9K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8/entry#A0A9J7G9K8-1", "sequence": { "sequence": "MVRPRRAPHRSGAXGPLGGRGRPPRPLVVRAVRSRSWPSGPRGPQPPRIRARSAPPMEGARVFGALGPIGPSSPGLSVGGLAVNEHRLSNKLLAWSGVLEWQEKRRPFSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNAIRQVITTRKQAVGPGGVHSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTDQWPRKLFMQLIPQQLLTTLVPLFRNSRLVQFHFTKDMETLKSLCRIMDNGFAGCVHFSYKASCEVRVLMLLYSSEKKIFIGLIPHDQSNFVNGIRRVIANQQQVLQRSLEQEQQQRGMGG", "length": 416, "header": "tr|A0A9J7G9K8-1|A0A9J7G9K8_CRIGR Isoform 1 of Prostate tumor-overexpressed gene 1 protein OS=Cricetulus griseus OX=10029 GN=Ptov1 PE=3 SV=1 CANONICAL=A0A9J7G9K8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767703", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767703", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K8", "url": 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"https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G9K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K8" }, { "id": "PF11232", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11232" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mediator complex subunit Med25 PTOV", "eco_id": "ECO_0000259", "start_pos": 90, "end_pos": 238, "start_aa": "Asn", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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} ], "protein_names": [ { "name": "Translation initiation factor eIF2B subunit delta", "type": "recommended", "evidence": [ { "id": "A0A9J7G9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9/entry#names_and_taxonomy" } ] }, { "name": "eIF2B GDP-GTP exchange factor subunit delta", "type": "synonym", "evidence": [ { "id": "A0A9J7G9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9/entry#names_and_taxonomy" } ] }, { "name": "translation initiation factor eIF-2B subunit delta isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016819641", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819641" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613640.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016819641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819641" } ] }, { "annotation": "Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on eukaryotic initiation factor 2 (eIF2) gamma subunit. 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"PTHR10233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10233:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10233:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016819641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819641", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M8K3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M8K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M8K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M9U0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M9U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9K9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC24-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTQQPAAPTSLPKLSRSLSGSLCALFSDAESRSEMKAELSPRPGAAGREMTQEEKLQLRKEKKQQKKKRKEEKGADQDVGSAVSAAQSQVDPTRELPAPGRELGGTAGEKIPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPQACPSTAGEATSGVKRLPEHLQVEGPTLLRRLVRKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQYMSIPSSVIHPAMVRLGLQYSQGLISGSNARCITLLRALQQVIQDYTTPPNEELSRDLVNKLKPYISFLTQCRPLSASMCNAIKFLNKEITGMSTSKREEEAKSELREAIDRYVQEKIVLAAQAISRFASKKISDGDVILVYGCSSLVSRILQEAWVEGRRFRVVVVDSRPRLEGRRMLRSLVHAGVPTSYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEQVALANWQNHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 545, "header": "tr|A0A9J7G9K9-1|A0A9J7G9K9_CRIGR Isoform 1 of Translation initiation factor eIF2B subunit delta OS=Cricetulus griseus OX=10029 GN=Eif2b4 PE=3 SV=1 CANONICAL=A0A9J7G9K9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M8K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9/entry#A0A8C2M8K3-1", "sequence": { "sequence": "MPTQQPAAPTSLPKLSRSLSGSLCALFSDAESRSEMKAELSPRPGAAGREMTQEEKLQLRKEKKQQKKKRKEEKGADQDVGSAVSAAQSQDPTRELPAPGRELGGTAGEKIPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPQACPSTAGEATSGVKRLPEHLQVEGPTLLRRLVRKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQYMSIPSSVIHPAMVRLGLQYSQGLISGSNARCITLLRALQQVIQDYTTPPNEELSRDLVNKLKPYISFLTQCRPLSASMCNAIKFLNKEITGMSTSKREEEAKSELREAIDRYVQEKIVLAAQAISRFASKKISDGDVILVYGCSSLVSRILQEAWVEGRRFRVVVVDSRPRLEGRRMLRSLVHAGVPTSYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEQVALANWQNHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 544, "header": "tr|A0A8C2M8K3-1|A0A8C2M8K3_CRIGR Computationally mapped isoform of Translation initiation factor eIF2B subunit delta OS=Cricetulus griseus OX=10029 GN=Eif2b4 PE=3 SV=1 CANONICAL=A0A9J7G9K9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2M9U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9/entry#A0A8C2M9U0-1", "sequence": { "sequence": "MAAVVVAVREESRSEMKAELSPRPGAAGREMTQEEKLQLRKEKKQQKKKRKEEKGADQDVGSAVSAAQSQDPTRELPAPGRELGGTAGEKIPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPQACPSTAGEATSGVKRLPEHLQVEGPTLLRRLVRKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQYMSIPSSVIHPAMVRLGLQYSQGLISGSNARCITLLRALQQVIQDYTTPPNEELSRDLVNKLKPYISFLTQCRPLSASMCNAIKFLNKEITGMSTSKREEEAKSELREAIDRYVQEKIVLAAQAISRFASKKISDGDVILVYGCSSLVSRILQEAWVEGRRFRVVVVDSRPRLEGRRMLRSLVHAGVPTSYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEQVALANWQNHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 524, "header": "tr|A0A8C2M9U0-1|A0A8C2M9U0_CRIGR Computationally mapped isoform of Translation initiation factor eIF2B subunit delta OS=Cricetulus griseus OX=10029 GN=Eif2b4 PE=3 SV=1 CANONICAL=A0A9J7G9K9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9/entry#A0A9J7G9K9-1", "sequence": { "sequence": "MPTQQPAAPTSLPKLSRSLSGSLCALFSDAESRSEMKAELSPRPGAAGREMTQEEKLQLRKEKKQQKKKRKEEKGADQDVGSAVSAAQSQVDPTRELPAPGRELGGTAGEKIPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPQACPSTAGEATSGVKRLPEHLQVEGPTLLRRLVRKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQYMSIPSSVIHPAMVRLGLQYSQGLISGSNARCITLLRALQQVIQDYTTPPNEELSRDLVNKLKPYISFLTQCRPLSASMCNAIKFLNKEITGMSTSKREEEAKSELREAIDRYVQEKIVLAAQAISRFASKKISDGDVILVYGCSSLVSRILQEAWVEGRRFRVVVVDSRPRLEGRRMLRSLVHAGVPTSYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEQVALANWQNHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 545, "header": "tr|A0A9J7G9K9-1|A0A9J7G9K9_CRIGR Isoform 1 of Translation initiation factor eIF2B subunit delta OS=Cricetulus griseus OX=10029 GN=Eif2b4 PE=3 SV=1 CANONICAL=A0A9J7G9K9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GC24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9/entry#A0A9J7GC24-1", "sequence": { "sequence": "MTQEEKLQLRKEKKQQKKKRKEEKGADQDVGSAVSAAQSQVDPTRELPAPGRELGGTAGEKIPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPQACPSTAGEATSGVKRLPEHLQVEGPTLLRRLVRKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQYMSIPSSVIHPAMVRLGLQYSQGLISGSNARCITLLRALQQVIQDYTTPPNEELSRDLVNKLKPYISFLTQCRPLSASMCNAIKFLNKEITGMSTSKREEEAKSELREAIDRYVQEKIVLAAQAISRFASKKISDGDVILVYGCSSLVSRILQEAWVEGRRFRVVVVDSRPRLEGRRMLRSLVHAGVPTSYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEQVALANWQNHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 495, "header": "tr|A0A9J7GC24-1|A0A9J7GC24_CRIGR Computationally mapped isoform of Translation initiation factor eIF2B subunit delta OS=Cricetulus griseus OX=10029 GN=Eif2b4 PE=3 SV=1 CANONICAL=A0A9J7G9K9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 514, "start_aa": "Thr", "end_pos": 514, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr514", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766948", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766948", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LPP5-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "EIF2B4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSQQPAVPSTSPPKPSRSLSSSLCALFSDADSGSGMKAELAPRPGAEGREMTQEEKLQLRKEKKQQKKKRKEEKGTETETGSAVSAAQCQVGPAKHLAGPDSQLGTAKEKVPAGRSKAELRAERRAKQEAERALKQARKGDQGGPPPQACPSTAGETPSGVKRLPEHSQVDDPTLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPSEELSRDLVNKLKPYFSFLTQCRPLSASMYNAIKFLNKEITGVSGSKREEEAKSELRAAIDRYIKEKIVLAAQAISRFAYKKISNGDVILGLPLCPLGMMVDSRPRLEAKHTLRSLVRAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLLCERGEHVALANWQNHSSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 529 }, "evidence": [ { "id": "A0A9J7G9K9", "url": "https://omabrowser.org/oma/group/A0A9J7G9K9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8M2B7A1-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "eif2b4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADSDGRQVDSINHATGEEGKLQDIVKAKSEGKELTKEEKQRLRKEKKQHKKNKKDDNKGPPEKEKEKEKEKASAPPPSKPVTQSPAHKAAAPAPVTASASETPAAAEKPAKTKAELRAERRARQDSERASKQGKKEGGQQSTSSKPKASPNELQPVVKRLPEHVQVDDPAALKKLAKKLERQQKSGQGCGLNITGVQVPLRSDYGYKVSLFSHLHQYSRKNPPTQQISIPATVIHPSIVRLGLQYSQGIIAGSNARSVALLHAFKQVIQDYSTPPNEELSRDLVNKLSPYISFLSQCRPLSASMGNAIKYIKKEISNIPNQCKEEEAKGKLQACIDSYINEKIILASEAISKYAIEKISNGDVILVYGCSSLVNHILCEAFEKQRQFRVIVVDSRPRLEGREALRRLVKKGIRCTYVLISALSYILPEVSKVFLGAHALLANGYVMSRVGTSQIALVAKAYNVPVLVCCETYKFCERVQTDSFVSNELDDPDDLIVTRNGKTHLENWQTVKSLGLLNLVYDVTPPDFVDLVITDLGMIPCTSVPVVLRVKNVDQ", "length": 555 }, "evidence": [ { "id": "A0A9J7G9K9", "url": "https://omabrowser.org/oma/group/A0A9J7G9K9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0Y022-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "EIF2B4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVTLTFWPLESSTSSTTSSVGICCVSCREKGLAAGIGSPAPSATHSGSGGPSRIIPARQLLPTCWALRRKLLKVSLPPSVGSCRTGMEAEQGEELVGKARGPTSTFTCSAAPQCLHPDRAPCAHGWLWFPCGWGSQGVHLCWSREREGAGDRGAALAALCIAGRRSGNDASYYQSAARNTETECCKLSTAGGRGQRWARVAAGRQPGQCHRGTKQGKRPRAAAPRLPACMYFSSCSLRCSTSAGGPELSREEKLQLRKEKKQQKKKKRNEKGTAAEPPEPGTAADPAQPRVTPHPASPPASANAPNDGEKPPGGKSKAELRAERRAKQEAERAQKQAKKAELGQGAAPAKPRLTPTEAPSVVKRLPEHVQVDDPAAQRKLAKKLERQQVPLRQDYGTKVNLFSHLHQYSRKKPLTQQMSIPSTVIHPAVVRLGLQYSQGIINGSNARCIALLEVFKQLIRDYSTPPNEELSRDLVAKLKPHISFLNQCRPLSVSMGNAIKFLKKEISCLPDTLREEEAKEKLQGTIDNYLREKIVLAAEAISKSAFEKINDNDVILVYGCSSLVNRTLCDAHTQTDRTFRVIVVDSRPRLEGRETLRRLVRHGIHCTYVMINAISYVLPEVSKVLLGAHALLANGSVMSRVGTSQIALVSKAYNVPVLVCCETYKFCERVQTDSFVSNELDDPDDLIVQRKGQAQLGGWAENKSLRLLNLVYDVTPPDLVDLVITDLGMIPCTSVPVVLRVKNVDQQ", "length": 747 }, "evidence": [ { "id": "A0A9J7G9K9", "url": "https://omabrowser.org/oma/group/A0A9J7G9K9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q61749-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "Eif2b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVAVAVREESRSEMKTELSPRPGAAGRELTQEEKLQLRKEKKQQKKKRKEEKGADQEIGSAVSAAQRQDPIRELPGPGSQLGGTAGEKLPAGRSKAELRAERRAKQEAERALKQARKGEQGGVPPQACPSTAGETTSGVKRVPEHTPADDPTLLRRLLRKPDRQQVPTRKDYGSKVSLFSHLPQYSRQSSLTQYMSIPSSVIHPAMVRLGLQYSQGLISGSNARCIALLHALQQVIQDYTTPPSEELSRDLVNKLKPYISFLTQCRPMSASMCNAIKFLTKEVTGMSSSKREEEAKSELREALDRYVQEKIVLAAQAISRFASTKISDGDVILVYGCSSLVSRILQEARVEGRRFRVVVVDSRPRLEGRHMLHSLVRAGVPTSYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGDQVALANWQSHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 524 }, "evidence": [ { "id": "A0A9J7G9K9", "url": "https://omabrowser.org/oma/group/A0A9J7G9K9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63186-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "Eif2b4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVAVAVREESRSEMKTELSPRPGAAGRELTQEEKLQLRKEKKQQKKKRKEEKGADQEIGSAVSAAQRQDPVRELQGTGSQLGGTTGEKLPAGRSKAELRAERRAKQEAERALKQARKGEQGGPSPQACPSTAGEATSGVKRVPEHTQADDPTLLRRLLRKPDRQQVPTRKDYGSKVSLFSHLPQYSRQSSLTQYMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLHALQQVIQDYTTPPNEELSRDLVNKLKPYISFLTQCRPMSASMCNAIKFFNKEVTGMSSSKREEEAKSELKEAIDRYVQEKIVLASQAISRFASKKISDGDVILVYGCSSLVSRILQEAWVEGRRFRVVVVDSRPRLEGRHMLHCLVRAGVPTSYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGDQVTLANWQNNSSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 524 }, "evidence": [ { "id": "A0A9J7G9K9", "url": "https://omabrowser.org/oma/group/A0A9J7G9K9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UI10-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "EIF2B4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ", "length": 523 }, "evidence": [ { "id": "A0A9J7G9K9", "url": "https://omabrowser.org/oma/group/A0A9J7G9K9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W1Q8-1", "protein_name": "Translation initiation factor eIF2B subunit delta", "gene_name": "eIF2Bdelta", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVLTSEQVPQTLKSKHKKQRQRNRPRNKRNRLEDSHSTTQETSAIDATSAMPGNAVDPLATEKTRDQIMAEREAKKLAKQAKKQKTAPTPTAATPAVLTTPSAPATKIITEVEQTTITTKLTTTTTTKVQDAVASKTTQPAAVNGKDAEAGEKTREQIKAEREAKKAAKKAGKGGGAKVEGIAQQLADLKVAEKAPVAASAAPSTTEADQEKKKPALSKAERRAIQEAQRAAKAQVQTKKAQHAAKAPPSAAPKGPNRKSVSPTTAATSSSPVKCPASTPNVDCRVKLFNHLVCAKEDSQFINDPLVHPSIARLGVQYAKRTVVGSNARCIAFLHALRQVVHDFETPAKKEFGRSLDAAVKHHVDHLHKCRPLAVSVSNAYKQFKNQLTQLPADVPETESKELLVHFIDTYIENQIGKAAQAISGFLQEKITDGDVLLTFACSSLIQFICEEAKRRQVAFRVIVVDSRPGCEGQELLRRLHATGIPCTYVLINAVGYVMAEATKVLLGAHALLANGYVMARTGTAQVALVANAHNVPVLVCCETHKFSERFQTDAIVYNELSDPNQLVRGDKCQLSNWAAKGKLLPLNLSYDITPPELVSAVVTEVAILPCTSVPVILRIKPDIGY", "length": 626 }, "evidence": [ { "id": "A0A9J7G9K9", "url": "https://omabrowser.org/oma/group/A0A9J7G9K9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9" } ], "pmid": "" }, { "name": "eukaryotic translation initiation factor 2B complex", "id": "GO:0005851", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005851", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9K9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9K9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 514 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 433, "end_pos": 435 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003613646.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497369" } ] }, { "annotation": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEMNLLPTPESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA", "length": 442, "header": "tr|A0A9J7G9M2-1|A0A9J7G9M2_CRIGR Isoform 1 of 26S proteasome regulatory subunit 6A OS=Cricetulus griseus OX=10029 GN=Psmc3 PE=3 SV=1 CANONICAL=A0A9J7G9M2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2/entry#A0A8C2LJR6-1", "sequence": { "sequence": "MNLLPTPESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA", "length": 439, "header": "tr|A0A8C2LJR6-1|A0A8C2LJR6_CRIGR Computationally mapped isoform of 26S proteasome regulatory subunit 6A OS=Cricetulus griseus OX=10029 GN=Psmc3 PE=3 SV=1 CANONICAL=A0A9J7G9M2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2/entry#A0A9J7G9M2-1", "sequence": { "sequence": "MQEMNLLPTPESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA", "length": 442, "header": "tr|A0A9J7G9M2-1|A0A9J7G9M2_CRIGR Isoform 1 of 26S proteasome regulatory subunit 6A OS=Cricetulus griseus OX=10029 GN=Psmc3 PE=3 SV=1 CANONICAL=A0A9J7G9M2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100689203", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100689203", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2" } ], "pmid": "" }, { "name": "proteasome complex", "id": "GO:0000502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000502", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G9M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9M2" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 222, "end_pos": 361, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007605733", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007605733" } ] }, { "annotation": "Transcriptional regulator that plays a role in retinal development and maintenance.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9S7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9S7#function" }, { "database": "UniProtKB", "id": "ARBA00053347", "url": "https://www.uniprot.org/uniprotkb/ARBA00053347#function" }, { "database": "UniProtKB", "id": "A0A8C2N1U8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1U8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9S7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9S7" } ], "common_name": "Chinese hamster", "glygen_name": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279908" } ] }, { "annotation": "One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2#function" }, { "database": "UniProtKB", "id": "ARBA00003922", "url": "https://www.uniprot.org/uniprotkb/ARBA00003922#function" } ] }, { "annotation": "Structural component of the gap junction, a specialized intercellular structure consisting of a cluster of closely packed pairs of transmembrane channels, the connexons, that allow passage of small molecules and electrical signals between neighboring cells. Forms homotypic and heterotypic channels gated by transjunctional voltage. Involved in intercellular innate immune signaling. Mediates translocation of 2',3'-cGAMP and 2',5'-oligoadenylates (2-5A) second messengers from virus-infected cells to macrophages and uninfected neighboring cells to propagate and amplify the antiviral immune response.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2#function" }, { "database": "UniProtKB", "id": "RU000630", "url": "https://www.uniprot.org/uniprotkb/RU000630#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gjd3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2", "locus": {} } ], "crossref": [ { "id": "A0A9J7G9U2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G9U2", "database": "AlphaFoldDB", "categories": [] }, { "id": "113839459", "url": "https://www.ncbi.nlm.nih.gov/gene/113839459", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019570", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019570", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113839459", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113839459", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9U2", "url": "https://www.orthodb.org/?gene=A0A9J7G9U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11984:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11984:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00029", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00029", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279908", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G9U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEWAFLGSLLDAVQLQSPLVGRLWLVIMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVIYSMHQASKEAGGAQPATPCTRGRPEAPCAPCSLRARRARRCYLLSVALRLLAELAFLGGQTLLYGFRVAPHYACAGPPCPHTVDCFVSRPTEKTVFVVFYFAVGLLSALLSVAELGHLLWKGRQRAKLLPPRRAARPPPALPSQRADPDPFGPPAYAHRAPAGDSEGEGGSGHSKASLATVRQDLAI", "length": 281, "header": "tr|A0A9J7G9U2-1|A0A9J7G9U2_CRIGR Isoform 1 of Gap junction protein OS=Cricetulus griseus OX=10029 GN=Gjd3 PE=3 SV=1 CANONICAL=A0A9J7G9U2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G9U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2/entry#A0A9J7G9U2-1", "sequence": { "sequence": "MGEWAFLGSLLDAVQLQSPLVGRLWLVIMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVIYSMHQASKEAGGAQPATPCTRGRPEAPCAPCSLRARRARRCYLLSVALRLLAELAFLGGQTLLYGFRVAPHYACAGPPCPHTVDCFVSRPTEKTVFVVFYFAVGLLSALLSVAELGHLLWKGRQRAKLLPPRRAARPPPALPSQRADPDPFGPPAYAHRAPAGDSEGEGGSGHSKASLATVRQDLAI", "length": 281, "header": "tr|A0A9J7G9U2-1|A0A9J7G9U2_CRIGR Isoform 1 of Gap junction protein OS=Cricetulus griseus OX=10029 GN=Gjd3 PE=3 SV=1 CANONICAL=A0A9J7G9U2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"id": "GO:0086077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086077", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "connexin complex", "id": "GO:0005922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005922", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9U2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G9U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9U2" }, { "id": "SM00037", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00037" } ], "ann_type": 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G9V4-1", "uniprot_ac": "A0A9J7G9V4", "uniprot_id": "A0A9J7G9V4_CRIGR", "mass": { "chemical_mass": 60789.0, "monoisotopic_mass": 60789.0 }, "refseq": { "ac": "XP_027279926", "name": "26S proteasome non-ATPase regulatory subunit 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279926" }, "gene_names": [ { "name": "LOC100759692", "type": "recommended", "evidence": [ { "id": "A0A9J7G9V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4" } ] }, { "name": "LOC100759692", "type": "synonym", "evidence": [ { "id": "XP_027279926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279926" } ] } ], "protein_names": [ { "name": "26S proteasome non-ATPase regulatory subunit 3", "type": "recommended", "evidence": [ { "id": "A0A9J7G9V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4/entry#names_and_taxonomy" } ] }, { "name": "26S proteasome non-ATPase regulatory subunit 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027279926", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279926" } ] }, { "name": "26S proteasome regulatory subunit RPN3", "type": "synonym", "evidence": [ { "id": "A0A9J7G9V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279926" } ] }, { "annotation": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4#function" }, { "database": "UniProtKB", "id": "ARBA00002362", "url": "https://www.uniprot.org/uniprotkb/ARBA00002362#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100759692", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4", "locus": {} } ], "crossref": [ { "id": "A0A9J7G9V4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G9V4", "database": 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Classification", "Other" ] }, { "id": "PF25573", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25573", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279926", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279926", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G9V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKQEGSARRRGADKAKPPPGGEQEPPPPPAPQDVEMKEEAAAGSGSTGEADGKAAATEHSQRELDTVTLEDIKEHVKQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVHGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASAPLLPEVEAYLQLLMVIFLMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQTDGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMTDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLESAEERREREQQDLEFAKEMAEDDDDSFP", "length": 531, "header": "tr|A0A9J7G9V4-1|A0A9J7G9V4_CRIGR Isoform 1 of 26S proteasome non-ATPase regulatory subunit 3 OS=Cricetulus griseus OX=10029 GN=LOC100759692 PE=3 SV=1 CANONICAL=A0A9J7G9V4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G9V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4/entry#A0A9J7G9V4-1", "sequence": { "sequence": "MKQEGSARRRGADKAKPPPGGEQEPPPPPAPQDVEMKEEAAAGSGSTGEADGKAAATEHSQRELDTVTLEDIKEHVKQLEKAVSGKEPRFVLRALRMLPSTSRRLNHYVLYKAVHGFFTSNNATRDFLLPFLEEPMDTEADLQFRPRTGKAASAPLLPEVEAYLQLLMVIFLMNSKRYKEAQKISDDLMQKISTQNRRALDLVAAKCYYYHARVYEFLDKLDVVRSFLHARLRTATLRHDADGQATLLNLLLRNYLHYSLYDQAEKLVSKSVFPEQANNNEWARYLYYTGRIKAIQLEYSEARRTMTNALRKAPQHTAVGFKQTVHKLLIVVELLLGEIPDRLQFRQPSLKRSLMPYFLLTQAVRTGNLAKFNQVLDQFGEKFQTDGTYTLIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAIRDGVIEASINHEKGYVQSKEMTDIYSTREPQLAFHQRISFCLDIHNMSVKAMRFPPKSYNKDLESAEERREREQQDLEFAKEMAEDDDDSFP", "length": 531, "header": "tr|A0A9J7G9V4-1|A0A9J7G9V4_CRIGR Isoform 1 of 26S proteasome non-ATPase regulatory subunit 3 OS=Cricetulus griseus OX=10029 GN=LOC100759692 PE=3 SV=1 CANONICAL=A0A9J7G9V4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759692", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759692", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4" } ], "pmid": "" }, { "name": "regulation of protein catabolic process", "id": "GO:0042176", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042176", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "proteasome regulatory particle, lid subcomplex", "id": "GO:0008541", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008541", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9V4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7G9V4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V4" }, { "id": "PS50250", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50250" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PCI", "eco_id": "ECO_0000259", "start_pos": 283, "end_pos": 462, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 485, "end_pos": 487 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7G9V5-1", "uniprot_ac": "A0A9J7G9V5", "uniprot_id": "A0A9J7G9V5_CRIGR", "mass": { "chemical_mass": 111097.0, "monoisotopic_mass": 111097.0 }, "refseq": { "ac": "XP_027241219", "name": "arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241219" }, "gene_names": [ { "name": "Asap2", "type": "recommended", "evidence": [ { "id": "A0A9J7G9V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V5" } ] }, { "name": "Asap2", "type": "synonym", "evidence": [ { "id": "XP_027241219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241219" } ] } ], "protein_names": [ { "name": "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7G9V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V5/entry#names_and_taxonomy" } ] }, { "name": "arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027241219", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241219" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1023 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616360.1) and transcript sequence (IACG01077175.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027241219.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027241219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241219" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Asap2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V5", "locus": {} } ], "crossref": [ { "id": "A0A9J7G9V5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7G9V5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07642", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07642", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08849", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08849", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11966", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11966", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13251", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13251", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759382", "url": "https://www.ncbi.nlm.nih.gov/gene/100759382", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759382", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759382", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9V5", "url": "https://www.orthodb.org/?gene=A0A9J7G9V5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45854:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45854:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027241219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241219", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYD1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9V5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKAINVSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKVKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQLRQSTAYSLHQPQGNKEHGTERNGNLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPEEKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPSEDSVKPNPGSDMIARKDYITAKYIERRYARKKHADTSAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDVDEKLQPSPNRREDRPISFYQLGSSQFQPNAVSLARDTANLTKDKQRGFGPSILQNETYGAILSGSPPSSQSLPPSTTSAPPLPPRNVGGKVQTATSANTLWKTNSVGVDGVSRQRSSSDLPAVHPPLPPLRVTSTNPLTTTPPPPVAKASGTLDGVNQPSKPAQPGASQSKPPLLPPQPPSRLPQKKPASGTDKPTPLINKGQPRGPEAPGPLSNAMALQPPAPMPRKSQVTKSKPKRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPSRKGAFPVSFVHFIAD", 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This record is derived from a genomic sequence (NW_003614015.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016831858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831858" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9V6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dlx4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V6", "locus": {} } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757892", "url": "https://www.ncbi.nlm.nih.gov/gene/100757892", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050460", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050460", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757892", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757892", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9V6", "url": "https://www.orthodb.org/?gene=A0A9J7G9V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24327", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24327", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24327:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24327:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016831858", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831858", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G9V6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSLPCPLPGRVVFPDLAPVPSVVAANPLGLSPETAASPDLSYSQPYGHLLSYSYLXAATPGDSYLLSQQLSEVPSQSFHRAAEHPQELETESEKPVLSPEPSQQPLTGKLHKPGTIYSSLQLQHLNQRFQHMQYLALPERAQLAVQLGWTHPNPGREIWFQYKCPQYKKLLKKNSGGQEEDFSGRHPSLSPCSPNLLSIWDLPKVGTLPTSGYDHGFGVWHQHHSPDMLFLPQMM", "length": 236, "header": "tr|A0A9J7G9V6-1|A0A9J7G9V6_CRIGR Isoform 1 of LOW QUALITY PROTEIN: homeobox protein DLX-4 OS=Cricetulus griseus OX=10029 GN=Dlx4 PE=4 SV=1 CANONICAL=A0A9J7G9V6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G9V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9V6/entry#A0A9J7G9V6-1", "sequence": { "sequence": "MTSLPCPLPGRVVFPDLAPVPSVVAANPLGLSPETAASPDLSYSQPYGHLLSYSYLXAATPGDSYLLSQQLSEVPSQSFHRAAEHPQELETESEKPVLSPEPSQQPLTGKLHKPGTIYSSLQLQHLNQRFQHMQYLALPERAQLAVQLGWTHPNPGREIWFQYKCPQYKKLLKKNSGGQEEDFSGRHPSLSPCSPNLLSIWDLPKVGTLPTSGYDHGFGVWHQHHSPDMLFLPQMM", "length": 236, "header": "tr|A0A9J7G9V6-1|A0A9J7G9V6_CRIGR Isoform 1 of LOW QUALITY PROTEIN: homeobox protein DLX-4 OS=Cricetulus griseus OX=10029 GN=Dlx4 PE=4 SV=1 CANONICAL=A0A9J7G9V6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GB08-1", "uniprot_ac": "A0A9J7GB08", "uniprot_id": "A0A9J7GB08_CRIGR", "mass": { "chemical_mass": 125469.0, "monoisotopic_mass": 125469.0 }, "refseq": { "ac": "XP_027280919", "name": "rab11 family-interacting protein 3 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280919" }, "gene_names": [ { "name": "Rab11fip3", "type": "recommended", "evidence": [ { "id": "A0A9J7GB08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08" } ] }, { "name": "Rab11fip3", "type": "synonym", "evidence": [ { "id": "XP_027280919", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280919" } ] } ], "protein_names": [ { "name": "Rab11 family-interacting protein 3 isoform X6", "type": "synonym", "evidence": [ { "id": "A0A9J7GB08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08/entry#names_and_taxonomy" } ] }, { "name": "rab11 family-interacting protein 3 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_027280919", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280919" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280919", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280919" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rab11fip3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08", "locus": {} } ], "crossref": [ { "id": "A0A9J7GB08", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GB08", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758750", "url": "https://www.ncbi.nlm.nih.gov/gene/100758750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758750", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758750", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GB08", "url": "https://www.orthodb.org/?gene=A0A9J7GB08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15726", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15726", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15726:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15726:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280919", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280919", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G9X8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9X8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9X8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB08-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSQPTSLSDHGEPASGPHRRVKGPVGPDAPRGWSDEPEEHAQLQRWPEGPNAPICWPEEVEEPDAPSRWVKEPNAPRCWSQEPDVSCHLAKELEEPDAPRCWPQEPDASCHLARELEEPVAPRCWPQEPDAQCLLAKELEEPDAARCCPQEPDAQCHLVKELEEPDAPRCCPQEPDAQCLLAKELEEPDASRCCPQEPDAQCLLVKELEEPDVPRCCPQEPDAQCLLAKELEEPDVPRCCPQEPNAQCLLAKELEEPDAPRCWPQEPDVPCLLAKEWEESDSPLLLAEELGEPDALHFWPQEPDAPCFLAVELEEPDAPHCSSQEANTVCLLAKKPEEPDTPLLWPGEPDVLSLLVKEPEEPGAPRCWPEEPEEPNEPDEPDTPRSPCFWGNEPEESDASCCWSEEPPVLCLWPEEQNATRCWQEEPDAPCFWPEDGEEPKVPCLQFKEPEKPKVPCSWPEELEDSCATRGLPLEHLPSESELLQACPGPPSDPGPALSLSSEPGTAQEEGARLRTVFDALDRDGDGFVRVEDFIQFATVYGAEQVKDLTQYLDPSGVGVISFEDFHQGIVAIRNGGLLSTDPDGQLYNVEPVQDEEPPACADEFDDFVTYEANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDTMEEPDHGALLLLPGRTHPHSQAVVMVIGSEEHFEDYGEGSEAELSPEALCNGELDCGDPSFLSPSSNPLASKLRNALTDEVFEFYCSQCHKQINRLEDLSARLTDLEMNSPAKRLSSRKVARYLHQSGTLTMEALDDPPPEPVECPEEDIADKVIFLERRVSELEKDSAAAGEQHGRLRQENLQLVHRANALEEQLKEQELRAQERVLEETRKQKELLCKMEREKSIEIENLQARLQQLDEENSELRSCTPCLKANIERLEEEKQKMLDEIEELTQRLSEEQENKRKMGDKLSHERHQFQRDKEATQELIEDLRKQLEHLQLLRLEVEQRRGRSSSLGLQEYNSRARESELEQEVRRLKQDNRNLKEQNDELNGQIITLSIQGAKSLFSTSFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAILETNPSILEVK", "length": 1114, "header": "tr|A0A9J7GB08-1|A0A9J7GB08_CRIGR Isoform 1 of Rab11 family-interacting protein 3 isoform X6 OS=Cricetulus griseus OX=10029 GN=Rab11fip3 PE=4 SV=1 CANONICAL=A0A9J7GB08-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G9X8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08/entry#A0A9J7G9X8-1", "sequence": { "sequence": "MELSQPTSLSDHGEPASGPHRRVKGPVGPDAPRGWSDEPEEHAQLQRWPEGPNAPICWPEEVEEPDAPSRWVKEPNAPRCWSQEPDVSCHLAKELEEPDAPRCWPQEPDASCHLARELEEPVAPRCWPQEPDAQCLLAKELEEPDAARCCPQEPDAQCHLVKELEEPDAPRCCPQEPDAQCLLAKELEEPDASRCCPQEPDAQCLLVKELEEPDVPRCCPQEPDAQCLLAKELEEPDVPRCCPQEPNAQCLLAKELEEPDAPRCWPQEPDVPCLLAKEWEESDSPLLLAEELGEPDALHFWPQEPDAPCFLAVELEEPDAPHCSSQEANTVCLLAKKPEEPDTPLLWPGEPDVLSLLVKEPEEPGAPRCWPEEPEEPNEPDEPDTPRSPCFWGNEPEESDASCCWSEEPPVLCLWPEEQNATRCWQEEPDAPCFWPEDGEEPKVPCLQFKEPEKPKVPCSWPEELEDSCATRGLPLEHLPSESELLQACPGPPSDPGPALSLSSEPGTAQEEGARLRTVFDALDRDGDGFVRVEDFIQFATVYGAEQVKDLTQYLDPSGVGVISFEDFHQGIVAIRNGGLLSTDPDGQLYNVEPVQDEEPPACADEFDDFVTYEANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDTMEEPDHGALLLLPGRTHPHSQAVVMVIGSEEHFEDYGEGSEAELSPEALCNGELDCGDPSFLSPSPAKRLSSRKVARYLHQSGTLTMEALDDPPPEPVECPEEDIADKVIFLERRVSELEKDSAAAGEQHGRLRQENLQLVHRANALEEQLKEQELRAQERVLEETRKQKELLCKMEREKSIEIENLQARLQQLDEENSELRSCTPCLKANIERLEEEKQKMLDEIEELTQRLSEEQENKRKMGDKLSHERHQFQRDKEATQELIEDLRKQLEHLQLLRLEVEQRRGRSSSLGLQEYNSRARESELEQEVRRLKQDNRNLKEQNDELNGQIITLSIQGAKSLFSTSFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAILETNPSILEVK", "length": 1069, "header": "tr|A0A9J7G9X8-1|A0A9J7GB08_CRIGR Computationally mapped isoform of Rab11 family-interacting protein 3 isoform X6 OS=Cricetulus griseus OX=10029 GN=Rab11fip3 PE=4 SV=1 CANONICAL=A0A9J7GB08-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08/entry#A0A9J7GAC1-1", "sequence": { "sequence": "MELSQPTSLSDHGEPASGPHRRVKGPVGPDAPRGWSDEPEEHAQLQRWPEGPNAPICWPEEVEEPDAPSRWVKEPNAPRCWSQEPDVSCHLAKELEEPDAPRCWPQEPDASCHLARELEEPVAPRCWPQEPDAQCLLAKELEEPDAARCCPQEPDAQCHLVKELEEPDAPRCCPQEPDAQCLLAKELEEPDASRCCPQEPDAQCLLVKELEEPDVPRCCPQEPDAQCLLAKELEEPDVPRCCPQEPNAQCLLAKELEEPDAPRCWPQEPDVPCLLAKEWEESDSPLLLAEELGEPDALHFWPQEPDAPCFLAVELEEPDAPHCSSQEANTVCLLAKKPEEPDTPLLWPGEPDVLSLLVKEPEEPGAPRCWPEEPEEPNEPDEPDTPRSPCFWGNEPEESDASCCWSEEPPVLCLWPEEQNATRCWQEEPDAPCFWPEDGEEPKVPCLQFKEPEKPKVPCSWPEELEDSCATRGLPLEHLPSESELLQACPGPPSDPGPALSLSSEPGTAQEEGARLRTVFDALDRDGDGFVRVEDFIQFATVYGAEQVKDLTQYLDPSGVGVISFEDFHQGIVAIRNGDPDGQLYNVEPVQDEEPPACADEFDDFVTYEANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDTMEEPDHGALLLLPGRTHPHSQAVVMVIGSEEHFEDYGEGSEAELSPEALCNGELDCGDPSFLSPSSNPLASKLRNALTDEVFEFYCSQCHKQINRLEDLSARLTDLEMNSPAKRLSSRKVARYLHQSGTLTMEALDDPPPEPVECPEEDIADKVIFLERRVSELEKDSAAAGEQHGRLRQENLQLVHRANALEEQLKEQELRAQERVLEETRKQKELLCKMEREKSIEIENLQARLQQLDEENSELRSCTPCLKANIERLEEEKQKMLDEIEELTQRLSEEQENKRKMGDKLSHERHQFQRDKEATQELIEDLRKQLEHLQLLRLEVEQRRGRSSSLGLQEYNSRARESELEQEVRRLKQDNRNLKEQNDELNGQIITLSIQGAKSLFSTSFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAILETNPSILEVK", "length": 1109, "header": "tr|A0A9J7GAC1-1|A0A9J7GAC1_CRIGR Computationally mapped isoform of Rab11 family-interacting protein 3 isoform X7 OS=Cricetulus griseus OX=10029 GN=Rab11fip3 PE=4 SV=1 CANONICAL=A0A9J7GB08-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB08-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08/entry#A0A9J7GB08-1", "sequence": { "sequence": "MELSQPTSLSDHGEPASGPHRRVKGPVGPDAPRGWSDEPEEHAQLQRWPEGPNAPICWPEEVEEPDAPSRWVKEPNAPRCWSQEPDVSCHLAKELEEPDAPRCWPQEPDASCHLARELEEPVAPRCWPQEPDAQCLLAKELEEPDAARCCPQEPDAQCHLVKELEEPDAPRCCPQEPDAQCLLAKELEEPDASRCCPQEPDAQCLLVKELEEPDVPRCCPQEPDAQCLLAKELEEPDVPRCCPQEPNAQCLLAKELEEPDAPRCWPQEPDVPCLLAKEWEESDSPLLLAEELGEPDALHFWPQEPDAPCFLAVELEEPDAPHCSSQEANTVCLLAKKPEEPDTPLLWPGEPDVLSLLVKEPEEPGAPRCWPEEPEEPNEPDEPDTPRSPCFWGNEPEESDASCCWSEEPPVLCLWPEEQNATRCWQEEPDAPCFWPEDGEEPKVPCLQFKEPEKPKVPCSWPEELEDSCATRGLPLEHLPSESELLQACPGPPSDPGPALSLSSEPGTAQEEGARLRTVFDALDRDGDGFVRVEDFIQFATVYGAEQVKDLTQYLDPSGVGVISFEDFHQGIVAIRNGGLLSTDPDGQLYNVEPVQDEEPPACADEFDDFVTYEANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDTMEEPDHGALLLLPGRTHPHSQAVVMVIGSEEHFEDYGEGSEAELSPEALCNGELDCGDPSFLSPSSNPLASKLRNALTDEVFEFYCSQCHKQINRLEDLSARLTDLEMNSPAKRLSSRKVARYLHQSGTLTMEALDDPPPEPVECPEEDIADKVIFLERRVSELEKDSAAAGEQHGRLRQENLQLVHRANALEEQLKEQELRAQERVLEETRKQKELLCKMEREKSIEIENLQARLQQLDEENSELRSCTPCLKANIERLEEEKQKMLDEIEELTQRLSEEQENKRKMGDKLSHERHQFQRDKEATQELIEDLRKQLEHLQLLRLEVEQRRGRSSSLGLQEYNSRARESELEQEVRRLKQDNRNLKEQNDELNGQIITLSIQGAKSLFSTSFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAILETNPSILEVK", "length": 1114, "header": "tr|A0A9J7GB08-1|A0A9J7GB08_CRIGR Isoform 1 of Rab11 family-interacting protein 3 isoform X6 OS=Cricetulus griseus OX=10029 GN=Rab11fip3 PE=4 SV=1 CANONICAL=A0A9J7GB08-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08/entry#A0A9J7GEJ9-1", "sequence": { "sequence": "MELSQPTSLSDHGEPASGPHRRVKGPVGPDAPRGWSDEPEEHAQLQRWPEGPNAPICWPEEVEEPDAPSRWVKEPNAPRCWSQEPDVSCHLAKELEEPDAPRCWPQEPDASCHLARELEEPVAPRCWPQEPDAQCLLAKELEEPDAARCCPQEPDAQCHLVKELEEPDAPRCCPQEPDAQCLLAKELEEPDASRCCPQEPDAQCLLVKELEEPDVPRCCPQEPDAQCLLAKELEEPDVPRCCPQEPNAQCLLAKELEEPDAPRCWPQEPDVPCLLAKEWEESDSPLLLAEELGEPDALHFWPQEPDAPCFLAVELEEPDAPHCSSQEANTVCLLAKKPEEPDTPLLWPGEPDVLSLLVKEPEEPGAPRCWPEEPEEPNEPDEPDTPRSPCFWGNEPEESDASCCWSEEPPVLCLWPEEQNATRCWQEEPDAPCFWPEDGEEPKVPCLQFKEPEKPKVPCSWPEELEDSCATRGLPLEHLPSESELLQACPGPPSDPGPALSLSSEPGTAQEEGARLRTVFDALDRDGDGFVRVEDFIQFATVYGAEQVKDLTQYLDPSGVGVISFEDFHQGIVAIRNGDPDGQLYNVEPVQDEEPPACADEFDDFVTYEANEVTDSAYMGSESTYSECETFTDEDTSTLVHPELQPEGDADSAGGSAVPSECLDTMEEPDHGALLLLPGRTHPHSQAVVMVIGSEEHFEDYGEGSEAELSPEALCNGELDCGDPSFLSPSPAKRLSSRKVARYLHQSGTLTMEALDDPPPEPVECPEEDIADKVIFLERRVSELEKDSAAAGEQHGRLRQENLQLVHRANALEEQLKEQELRAQERVLEETRKQKELLCKMEREKSIEIENLQARLQQLDEENSELRSCTPCLKANIERLEEEKQKMLDEIEELTQRLSEEQENKRKMGDKLSHERHQFQRDKEATQELIEDLRKQLEHLQLLRLEVEQRRGRSSSLGLQEYNSRARESELEQEVRRLKQDNRNLKEQNDELNGQIITLSIQGAKSLFSTSFSESLAAEISSVSRDELMEAIQKQEEINFRLQDYIDRIIVAILETNPSILEVK", "length": 1064, "header": "tr|A0A9J7GEJ9-1|A0A9J7GEJ9_CRIGR Computationally mapped isoform of Rab11 family-interacting protein 3 isoform X9 OS=Cricetulus griseus OX=10029 GN=Rab11fip3 PE=4 SV=1 CANONICAL=A0A9J7GB08-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB08/entry#A0A9J7JXM3-1", "sequence": { "sequence": 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"MDGRWQHSHWAWSLLAMAVVAGGTASTEASDNSPTSNSLEGGADATAYWWGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGAGNRTCVGTSKRYQLCRVQECPPDGRSFREEQCVSFNSRVYDGRAYQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGVCQGDGSSCTHVTGNYRKGNNHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGFYFFNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHTHHLQPVYYSFSEPASESTESTEGQELDSARLLGFMQHNGSLYHQASSERLGLNNKLFQSPVPEVELGPSRGQETNEVCERASGGACEGPPRGKGFQDHNATGIALSGDKDDQEVDTRFTSQELLSANAISDQLLGTGSDSEEFSLNETMNSVFSQGAPRNSPAESLYVDYEENEGPAAYLINGSYLELSSDRINTSSEAPFPNTSASLPTLAGNRTHKARTRPKARKQGVSPADMYRWKLSSHEPCSATCTTGVMSTYAMCVRYDGVEVDDSYCDALTRPEPVHEFCAGRECQPRWETSSWSECSRTCGEGHQFRIVRCWKMLSPGFDSSVYSDLCEATEAVRPEERKICRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPSTRPVGEKNCTGPPCDRQWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQMRSGPECGLSRKPPEESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDSCQDQPGTNCALAIKVNLCSHWYYSKACCRSCRPPHS", "length": 957, "header": "tr|A0A9J7GA56-1|A0A9J7GA56_CRIGR Isoform 1 of ADAMTS-like protein 2 OS=Cricetulus griseus OX=10029 GN=LOC100761699 PE=4 SV=1 CANONICAL=A0A9J7GA56-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GA56-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA56/entry#A0A9J7GA56-1", "sequence": { "sequence": "MDGRWQHSHWAWSLLAMAVVAGGTASTEASDNSPTSNSLEGGADATAYWWGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGAGNRTCVGTSKRYQLCRVQECPPDGRSFREEQCVSFNSRVYDGRAYQWKPLYPDDYVHISSKPCDLHCTTVDGQRQLMVPARDGTSCKLTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGVCQGDGSSCTHVTGNYRKGNNHLGYSLVTHIPAGARDIQIVERKKSADVLALADEAGFYFFNGNYKVDSPKNFNIAGTVVKYRRPMDVYETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHTHHLQPVYYSFSEPASESTESTEGQELDSARLLGFMQHNGSLYHQASSERLGLNNKLFQSPVPEVELGPSRGQETNEVCERASGGACEGPPRGKGFQDHNATGIALSGDKDDQEVDTRFTSQELLSANAISDQLLGTGSDSEEFSLNETMNSVFSQGAPRNSPAESLYVDYEENEGPAAYLINGSYLELSSDRINTSSEAPFPNTSASLPTLAGNRTHKARTRPKARKQGVSPADMYRWKLSSHEPCSATCTTGVMSTYAMCVRYDGVEVDDSYCDALTRPEPVHEFCAGRECQPRWETSSWSECSRTCGEGHQFRIVRCWKMLSPGFDSSVYSDLCEATEAVRPEERKICRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPSTRPVGEKNCTGPPCDRQWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQMRSGPECGLSRKPPEESTCFERPCFKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDSCQDQPGTNCALAIKVNLCSHWYYSKACCRSCRPPHS", "length": 957, "header": "tr|A0A9J7GA56-1|A0A9J7GA56_CRIGR Isoform 1 of ADAMTS-like protein 2 OS=Cricetulus griseus OX=10029 GN=LOC100761699 PE=4 SV=1 CANONICAL=A0A9J7GA56-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 915, "start_aa": "Thr", "end_pos": 915, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr915", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA56", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA56" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA56", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA56" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761699", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA56", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA56" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA56", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA56" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA56", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA56" } ], "pmid": "" }, { "name": "negative regulation of transforming growth factor beta receptor signaling pathway", "id": "GO:0030512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030512", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA56", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { 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"type": "synonym", "evidence": [ { "id": "XP_027276922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276922" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7GA59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA59/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4C11-like", "type": "synonym", "evidence": [ { "id": "XP_027276922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276922" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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}, { "name": "olfactory receptor 1052", "type": "synonym", "evidence": [ { "id": "XP_027276967", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276967" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027276967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276967" } ] }, { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA94", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA94#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA94", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA94" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100755574", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA94", "locus": {} } ], "crossref": [ { "id": "A0A9J7GA94", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GA94", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15415", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15415", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755574", "url": "https://www.ncbi.nlm.nih.gov/gene/100755574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755574", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GA94", "url": "https://www.orthodb.org/?gene=A0A9J7GA94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027276967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027276967", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GA94", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GA94-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA94-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIWNHTRVKEFILVGLTENPNWEVPLFLLFSLIYLVILVGNWGMIILIWLNAQLHTPMYFFLSNLSFCDICYSTVFAPKMLVNFLSECKSSTFLACVLQSFFFAVYVTTEGILLSMMAYDRYVAITNPLMYTVIMTHSICTQMVLACYLGGLINSLTHTIGLLRLDFCGPNIVNHFFCDIPPLLKLSCSDAHINEMLLLIFSGVIAIFTFIIIIVSYSHIIIAILRIRSVEGRHKAFSTCASHLTAVTLFYGSVAFSYIQPSSQYSMEQEKVSAVFYTLIIPMLNPLIYSLRNKDVKEAAKRSICMSRSTS", "length": 312, "header": "tr|A0A9J7GA94-1|A0A9J7GA94_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100755574 PE=3 SV=1 CANONICAL=A0A9J7GA94-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GA94-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA94/entry#A0A9J7GA94-1", "sequence": { "sequence": "MAIWNHTRVKEFILVGLTENPNWEVPLFLLFSLIYLVILVGNWGMIILIWLNAQLHTPMYFFLSNLSFCDICYSTVFAPKMLVNFLSECKSSTFLACVLQSFFFAVYVTTEGILLSMMAYDRYVAITNPLMYTVIMTHSICTQMVLACYLGGLINSLTHTIGLLRLDFCGPNIVNHFFCDIPPLLKLSCSDAHINEMLLLIFSGVIAIFTFIIIIVSYSHIIIAILRIRSVEGRHKAFSTCASHLTAVTLFYGSVAFSYIQPSSQYSMEQEKVSAVFYTLIIPMLNPLIYSLRNKDVKEAAKRSICMSRSTS", "length": 312, "header": "tr|A0A9J7GA94-1|A0A9J7GA94_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100755574 PE=3 SV=1 CANONICAL=A0A9J7GA94-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280706" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccnf", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7", "locus": {} } ], "crossref": [ { "id": "A0A9J7GAB7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GAB7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20521", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20521", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"https://www.orthodb.org/?gene=A0A9J7GAB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280706", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280706", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GAB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGERGVIHCRCAKCFCYPTKRRIKRRPRNLTILSLPEDVLFHILKWLSVGDILAVRAVHSHLKYLVDNHASVWASASFQELWPSPKNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEACAEVNGLKASRFFSMAEKLNMGSEPFIWLFIRPPWSASGSCCKAVVHDSLRAECQLQRAHKASILHCLGRVLNLFEDEEKRKQARALFEESAHQGCLASSYLLWESDRRMDMSDPGRCLHNFRKLRDYAAKGCWEAQLALAKACAGGSQLGLEGKACNETVCQLFQASQAVNKQRVFSVQKGLSDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLQRRLVPRYKLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVASRTQHLCSFLCELSLLHTSLSIYAPARLASAALLLARLMHGQIQPWTTHLWDITGFSYNDLTPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKCYDEISQEEVLSYAELCTALGVKQESPEPSSFPSTGEIHTFLSSPSGRRNKRKRENSLQEDRGSFVTTPTAELSSQEETLLGSLLDWSLDCCSGYEGDQESEGEKEGDVTAPSGLLDVTVVYMNPEQHCCQESSDEEAWPEDKGHQAAHPTPALRPLLCNRGDLGKDITTSGYSSVSSLSPISSLDGGMRGSPRSTSVLSVGSYSNTKPCHHQAKKSCLQCRPPNPPESGVHQQRVKRQNLSVHSDEDTNLGFLKL", "length": 776, "header": "tr|A0A9J7GAB7-1|A0A9J7GAB7_CRIGR Isoform 1 of Cyclin-F OS=Cricetulus griseus OX=10029 GN=Ccnf PE=3 SV=1 CANONICAL=A0A9J7GAB7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GAB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7/entry#A0A9J7GAB7-1", "sequence": { "sequence": "MGERGVIHCRCAKCFCYPTKRRIKRRPRNLTILSLPEDVLFHILKWLSVGDILAVRAVHSHLKYLVDNHASVWASASFQELWPSPKNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSDEACAEVNGLKASRFFSMAEKLNMGSEPFIWLFIRPPWSASGSCCKAVVHDSLRAECQLQRAHKASILHCLGRVLNLFEDEEKRKQARALFEESAHQGCLASSYLLWESDRRMDMSDPGRCLHNFRKLRDYAAKGCWEAQLALAKACAGGSQLGLEGKACNETVCQLFQASQAVNKQRVFSVQKGLSDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLQRRLVPRYKLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTLVPVASRTQHLCSFLCELSLLHTSLSIYAPARLASAALLLARLMHGQIQPWTTHLWDITGFSYNDLTPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKCYDEISQEEVLSYAELCTALGVKQESPEPSSFPSTGEIHTFLSSPSGRRNKRKRENSLQEDRGSFVTTPTAELSSQEETLLGSLLDWSLDCCSGYEGDQESEGEKEGDVTAPSGLLDVTVVYMNPEQHCCQESSDEEAWPEDKGHQAAHPTPALRPLLCNRGDLGKDITTSGYSSVSSLSPISSLDGGMRGSPRSTSVLSVGSYSNTKPCHHQAKKSCLQCRPPNPPESGVHQQRVKRQNLSVHSDEDTNLGFLKL", "length": 776, "header": "tr|A0A9J7GAB7-1|A0A9J7GAB7_CRIGR Isoform 1 of Cyclin-F OS=Cricetulus griseus OX=10029 GN=Ccnf PE=3 SV=1 CANONICAL=A0A9J7GAB7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 671, "start_aa": "Thr", "end_pos": 671, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr671", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774506", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774506", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7" } ], "pmid": "" }, { "name": "negative regulation of centrosome duplication", "id": "GO:0010826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010826", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277016" } ] }, { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100761084", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9", "locus": {} } ], "crossref": [ { "id": "A0A9J7GAC9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GAC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15412", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15412", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761084", "url": "https://www.ncbi.nlm.nih.gov/gene/100761084", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761084", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761084", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GAC9", "url": "https://www.orthodb.org/?gene=A0A9J7GAC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277016", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GAC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKKNYTAVTEFIFLGLTDRAELQPVLFVVFLLIYLITVIGNVTMIFLNRSDAKLHTPMYFFLSHLSFVDLCYATTVAPQMLFNFLSKRKNISFIGCIIQFHFFIAFVITDYYMLAVMAYDRYMAICKPLLYTSKMSRSVCFSLVAAQYIYGFVNGLIQTVLMLRLTFCGPNEINHFYCADPPLMVLACSDTYVKETAMFVVAGSNLTCSLTIILISYIFIFSAILRIHSAEGRHKAFSTCGSHLTAVTIFYGTLFCMHLRPPSETSVEQGKIVAVFYIFVSPMLNPFIYSLRNKDVKNAMRKIMQK", "length": 307, "header": "tr|A0A9J7GAC9-1|A0A9J7GAC9_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100761084 PE=3 SV=1 CANONICAL=A0A9J7GAC9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GAC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9/entry#A0A9J7GAC9-1", "sequence": { "sequence": "MLKKNYTAVTEFIFLGLTDRAELQPVLFVVFLLIYLITVIGNVTMIFLNRSDAKLHTPMYFFLSHLSFVDLCYATTVAPQMLFNFLSKRKNISFIGCIIQFHFFIAFVITDYYMLAVMAYDRYMAICKPLLYTSKMSRSVCFSLVAAQYIYGFVNGLIQTVLMLRLTFCGPNEINHFYCADPPLMVLACSDTYVKETAMFVVAGSNLTCSLTIILISYIFIFSAILRIHSAEGRHKAFSTCGSHLTAVTIFYGTLFCMHLRPPSETSVEQGKIVAVFYIFVSPMLNPFIYSLRNKDVKNAMRKIMQK", "length": 307, "header": "tr|A0A9J7GAC9-1|A0A9J7GAC9_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100761084 PE=3 SV=1 CANONICAL=A0A9J7GAC9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761084", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761084", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GAC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAC9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GAF4-1", "uniprot_ac": "A0A9J7GAF4", "uniprot_id": "A0A9J7GAF4_CRIGR", "mass": { "chemical_mass": 112267.0, "monoisotopic_mass": 112267.0 }, "refseq": { "ac": "XP_027280996", "name": "serine/threonine-protein kinase 10 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280996" }, "gene_names": [ { "name": "Stk10", "type": "recommended", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "name": "Stk10", "type": "synonym", "evidence": [ { "id": "XP_027280996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280996" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein kinase 10 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027280996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280996" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280996" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Stk10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4", "locus": {} } ], "crossref": [ { "id": "A0A9J7GAF4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GAF4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06644", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06644", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769190", "url": "https://www.ncbi.nlm.nih.gov/gene/100769190", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051585", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051585", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769190", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769190", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GAF4", "url": "https://www.orthodb.org/?gene=A0A9J7GAF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46538", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46538", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46538:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46538:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280996", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GAF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFANFRRILRLSNFEKRKSREYEHVRRDLDPNEVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSVTSNKALRELVAEAKAEVMEEIEDARDDVRDDGEEEEAMDATSPLVNHTQDSAVATETSLNSDNPPQDSCVTLPPSQPQEPVNKPCSQPSGDGPLQTTSPADEVPKNDSDSKVPVSLRKSRPLSMDARIQVAEEKEVTGQAEDSSPVASKSQKANQSRPNSVALETLGGEKLANGGLGLPSSVVPGHAKRASDCSSLSTSESMDYGSSLSADLSLNKETGSLSLKGSKLHNKTLKRTRRFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSSKHELQLEQMHKRFEQEINAKKKFYDVELENLERQQKQQVEKMEQDHSVRRREEAKRIRLEQDRDYAKFQEQLKQMKKEVKNEVEKLPRQQRKESMKQKMEEHSQKKQLLDRDFVAKQKEDLELAMKKLTTENRREICDKERECLSKKQELLRDREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHELLRKHEKEREQMQRYNQRMMEQLKIRQQQEKARLPKIQRSDGKTRMAMYKKSLHINGAGSASEQREKIKQFSQQEEKRQKAERLQQQQKHENQMRDMVAQCESNMSELQQLQNEKCHLLVEHETQKLKALDENHNQSLKEWRDKLRPRKKALEEDLNQKKREQEMFFKLSEEAEPRPTTPNRASKFFPYSSGDAS", "length": 970, "header": "tr|A0A9J7GAF4-1|A0A9J7GAF4_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Stk10 PE=3 SV=1 CANONICAL=A0A9J7GAF4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GAF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4/entry#A0A9J7GAF4-1", "sequence": { "sequence": 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"tr|A0A9J7GAF4-1|A0A9J7GAF4_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Stk10 PE=3 SV=1 CANONICAL=A0A9J7GAF4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769190", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 879, "end_pos": 881, "annotation": "n_glycosylation_sequon" }, { "start_pos": 910, "end_pos": 912, "annotation": "n_glycosylation_sequon" } ], 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"G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "A0A9J7JYC5-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", 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"A0A9J7G1D9-1", "A0A9J7F985-1", "A0A9J7G270-1", "A0A9J7K1H4-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", "A0A8C2QHF9-1", "A0A8C2QI80-1", "A0A8C2QKP7-1", "A0A9J7FFS7-1", "A0A9J7FI14-1", "A0A9J7FJ23-1", "A0A9J7JLH7-1", "A0A8C2MH43-1", "A0A9J7FZ18-1", "A0A9J7G368-1", "A0A9J7G6S5-1", "A0A9J7H2T6-1", "A0A9J7H3N1-1", "A0A9J7H8L4-1", "A0A9J7JIW6-1", "A0A9J7JRI3-1", "A0A061ILI7-1", "A0A061HUS7-1", "A0A061HVM6-1", "A0A061I033-1", "A0A061I8L6-1", "A0A061I9F9-1", "A0A8C2MQS3-1", "A0A9J7F0Y2-1", "A0A9J7EZ49-1", "A0A8C2M6A3-1", "A0A8C2MQL9-1", "A0A8C2LY02-1", "A0A8C2LZT2-1", "A0A8C2M165-1", "A0A8C2M5G2-1", "A0A8C2M3Y9-1", "A0A8C2M5A7-1", "A0A8C2M9B6-1", "A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A8C2ML15-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", "A0A9J7KE81-1", "A0A9J7JPE2-1", "A0A9J7F773-1", "A0A8C2L7R1-1", "A0A8C2LHE9-1", "A0A3L7I870-1", "A0A3L7IB60-1", "A0A3L7IBX6-1", "A0A3L7ID00-1", "A0A3L7IEL5-1", "A0A3L7IER1-1", "A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMC9-1", "A0A8C2LMJ0-1", "A0A9J7JQV6-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "A0A8C2MYH0-1", "A0A8C2MV78-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N4W2-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A9J7F0N6-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F3R3-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7FLY5-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] } ] }, { "uniprot_ac": "A0A8C2N3U2", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ 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"id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2E9" } ] } ] }, { "uniprot_ac": "A0A9J7H2P9", "gene_name": "LOC113839030", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P9" } ] } ] }, { "uniprot_ac": "A0A9J7H2T6", "gene_name": "Ttn", "activity": [ { "ec_number": "2.7.11.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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This record is derived from a genomic sequence (NW_003613705.1) annotated using gene prediction method: Gnomon. 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF16608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278105", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278105", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GAH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4B8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4B8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEKKKKKQEDKKKKEGAQKKAADQKTKVPELTKTCSSQPQPAGTGTASTSTISSSSNGKRASACGQQPAASRYLPREVPPRFRQQEQKQLLKRGQPLPTGTLTSVSPAGASPPPLPGAGTQQHPSKLQPDPGHSGLADHYENSHWGQQPSYRSEANCGWDKVTLDRTDQEVWPSIPVTETESASECPADTDSASTCGSENSSMATGSTQGSFTGHPKKTNGNNGTNGALVQSPSNQSALGAGGTNGNGGVARVWGVATGSSSGLTHCSVGGGDGKMDNMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGSQNGNPVGTVGAWGNLLPQESTEPQTSTCQNVSFSVQPQNLNTDGSNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQGSGSGGEGMGSSVWGLSPGNPATGNNNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGNGGNAWDSGPPAGPGILAWGRGSGNNGIGNIHSGAWGHPSRSSSNGMNGEWGKLPNQHSSSDISGKGSTGWDSPSAASQPPALQPGSEHVSSWAKATSSGTTPSEGSSDGSGHHSEGGAGREAMGEGRRRDQGHIQLPRGDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGSAATQPSNSGGKSDGSLMNSTNTSSVSGWVSSPPAAVPANTSWGDSNNKAPSGPGVWGDSISSTAVNNAAATKSGHAWSGTVNQEDKSPTWGEPQKPKSQNWGDGQRANPAWSAGAGDWADSSSVLGHLGDGKKNGPGWDADGNRSGSGWNDASRCGTSGWASGASAKVNPGTNWGESLKPGPQQSWAHKPQDSNVSNWGGAASVKQTGTGWIGGPLPVKQKDSCEATGWEEPSPPSIRRKMEIDDGTSAWGDPSTYNNKTVNMWDRNNPVIQSSTTTPATPTTPTSSSTTHQAETPPSHQAGTQLNRSPLLGPVSSGWGEMPSVHSKAENSWGEPSSPSPLVDNGTAAWGKPPSSGSGWDHPAEPVVPFGRASAPAAAPALCKPASKSMQEGWGSGGDEMNLGASQWEDEDGDMWNNGVSQEGSSSCSSWGNASKKGLQKGMKTPGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNSMNLDQAMSALLEKKVDMDKRGLGMTDYNGMVTKTLGCRPPISKESSMDRPTFLDKDGGLVEEPTTSPFLPSPSLKLPLSNSALPNQALGGIASGLGMQNLNSSRQIPSGNLGVFGNSGAAQARTMQQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLSPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGPMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPPHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSIDVSSGLSVKDSSQSQSRLPQWTHPNSMGNLSSAASPLDQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSISWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPASHTQASLSHELWKVPRNTTAPTRPPPGLANPKPSSTWGTSPLGWTSSYSSGSAWSTDASGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQPSSGGSQPRLGSSGSTHGLVRSDTAHWSTPCLSGKGSSELLWGGVPQYSSSLWGPPSADDARVIGSPTPLNTLLPGDLLSGESM", "length": 1880, "header": "tr|A0A9J7GAV4-1|A0A9J7GAV4_CRIGR Isoform 1 of Trinucleotide repeat-containing gene 6C protein OS=Cricetulus griseus OX=10029 GN=Tnrc6c PE=3 SV=1 CANONICAL=A0A9J7GAV4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GAH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4/entry#A0A9J7GAH5-1", "sequence": { "sequence": "MEEKKKKKQEDKKKKEGAQKKAADQKTKVPELTKTCSSQPQPAGTGTASTSTISSSSNGKRASACGQQPAASRYLPREVPPRFRQQEQKQLLKRGQPLPTGTLTSVSPAGASPPPLPGAGTQQHPSKLQPDPGHSGLADHYENSHWGQQPSYRSEANCGWDKVTLDRTDQEVWPSIPVTETESASECPADTDSASTCGSENSSMATGSTQGSFTGHPKKTNGNNGTNGALVQSPSNQSALGAGGTNGNGGVARVWGVATGSSSGLTHCSVGGGDGKMDNMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGSQNGNPVGTVGAWGNLLPQESTEPQTSTCQNVSFSVQPQNLNTDGSNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQGSGSGGEGMGSSVWGLSPGNPATGNNNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGNGGNAWDSGPPAGPGILAWGRGSGNNGIGNIHSGAWGHPSRSSSNGMNGEWGKLPNQHSSSDISGKGSTGWDSPSAASQPPALQPGSEHVSSWAKATSSGTTPSEGSSDGSGHHSEGGAGREAMGEGRRRDQGHIQLPRGDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGSAATQPSNSGGKSDGSLMNSTNTSSVSGWVSSPPAAVPANTSWGDSNNKAPSGPGVWGDSISSTAVNNAAATKSGHAWSGTVNQEDKSPTWGEPQKPKSQNWGDGQRANPAWSAGAGDWADSSSVLGHLGDGKKNGPGWDADGNRSGSGWNDASRCGTSGWASGASAKVNPGTNWGESLKPGPQQSWAHKPQDSNVSNWGGAASVKQTGTGWIGGPLPVKQKDSCEATGWEEPSPPSIRRKMEIDDGTSAWGDPSTYNNKTVNMWDRNNPVIQSSTTTPATPTTPTSSSTTHQAETPPSHQAGTQLNRSPLLGPVSSGWGEMPSVHSKAENSWGEPSSPSPLVDNGTAAWGKPPSSGSGWDHPAEPVVPFGRASAPAAAPALCKPASKSMQEGWGSGGDEMNLGASQWEDEDGDMWNNGVSQEGSSSCSSWGNASKKGLQKGMKTPGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNSMNLDQAMSALLEKKVDMDKRGLGMTDYNGMVTKTLGCRPPISKESSMDRPTFLDKIPSGNLGVFGNSGAAQARTMQQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLSPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGPMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPPHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSIDVSSGLSVKDSSQSQSRLPQWTHPNSMGNLSSAASPLDQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSISWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPASHTQASLSHELWKVPRNTTAPTRPPPGLANPKPSSTWGTSPLGWTSSYSSGSAWSTDASGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQPSSGGSQPRLGSSGSTHGLVRSDTAHWSTPCLSGKGSSELLWGGVPQYSSSLWGPPSADDARVIGSPTPLNTLLPGDLLSGESM", "length": 1830, "header": "tr|A0A9J7GAH5-1|A0A9J7GAV4_CRIGR Computationally mapped isoform of Trinucleotide repeat-containing gene 6C protein OS=Cricetulus griseus OX=10029 GN=Tnrc6c PE=3 SV=1 CANONICAL=A0A9J7GAV4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4/entry#A0A9J7GAV4-1", "sequence": { "sequence": "MEEKKKKKQEDKKKKEGAQKKAADQKTKVPELTKTCSSQPQPAGTGTASTSTISSSSNGKRASACGQQPAASRYLPREVPPRFRQQEQKQLLKRGQPLPTGTLTSVSPAGASPPPLPGAGTQQHPSKLQPDPGHSGLADHYENSHWGQQPSYRSEANCGWDKVTLDRTDQEVWPSIPVTETESASECPADTDSASTCGSENSSMATGSTQGSFTGHPKKTNGNNGTNGALVQSPSNQSALGAGGTNGNGGVARVWGVATGSSSGLTHCSVGGGDGKMDNMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGSQNGNPVGTVGAWGNLLPQESTEPQTSTCQNVSFSVQPQNLNTDGSNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQGSGSGGEGMGSSVWGLSPGNPATGNNNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGNGGNAWDSGPPAGPGILAWGRGSGNNGIGNIHSGAWGHPSRSSSNGMNGEWGKLPNQHSSSDISGKGSTGWDSPSAASQPPALQPGSEHVSSWAKATSSGTTPSEGSSDGSGHHSEGGAGREAMGEGRRRDQGHIQLPRGDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGSAATQPSNSGGKSDGSLMNSTNTSSVSGWVSSPPAAVPANTSWGDSNNKAPSGPGVWGDSISSTAVNNAAATKSGHAWSGTVNQEDKSPTWGEPQKPKSQNWGDGQRANPAWSAGAGDWADSSSVLGHLGDGKKNGPGWDADGNRSGSGWNDASRCGTSGWASGASAKVNPGTNWGESLKPGPQQSWAHKPQDSNVSNWGGAASVKQTGTGWIGGPLPVKQKDSCEATGWEEPSPPSIRRKMEIDDGTSAWGDPSTYNNKTVNMWDRNNPVIQSSTTTPATPTTPTSSSTTHQAETPPSHQAGTQLNRSPLLGPVSSGWGEMPSVHSKAENSWGEPSSPSPLVDNGTAAWGKPPSSGSGWDHPAEPVVPFGRASAPAAAPALCKPASKSMQEGWGSGGDEMNLGASQWEDEDGDMWNNGVSQEGSSSCSSWGNASKKGLQKGMKTPGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNSMNLDQAMSALLEKKVDMDKRGLGMTDYNGMVTKTLGCRPPISKESSMDRPTFLDKDGGLVEEPTTSPFLPSPSLKLPLSNSALPNQALGGIASGLGMQNLNSSRQIPSGNLGVFGNSGAAQARTMQQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLSPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGPMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPPHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSIDVSSGLSVKDSSQSQSRLPQWTHPNSMGNLSSAASPLDQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSISWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPASHTQASLSHELWKVPRNTTAPTRPPPGLANPKPSSTWGTSPLGWTSSYSSGSAWSTDASGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQPSSGGSQPRLGSSGSTHGLVRSDTAHWSTPCLSGKGSSELLWGGVPQYSSSLWGPPSADDARVIGSPTPLNTLLPGDLLSGESM", "length": 1880, "header": "tr|A0A9J7GAV4-1|A0A9J7GAV4_CRIGR Isoform 1 of Trinucleotide repeat-containing gene 6C protein OS=Cricetulus griseus OX=10029 GN=Tnrc6c PE=3 SV=1 CANONICAL=A0A9J7GAV4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4/entry#A0A9J7H4B8-1", "sequence": { "sequence": "MEEKKKKKQEDKKKKEGAQKKAADQKTKVPELTKTCSSQPQPAGTGTASTSTISSSSNGKRASACGQQPAASRYLPREVPPRFRQQEQKQLLKRGQPLPTGTLTSVSPAGASPPPLPGAGTQQHPSKLQPDPGHSGLADHYENSHWGQQPSYRSEANCGWDKVTLDRTDQEVWPSIPVTETESASECPADTDSASTCGSENSSMATGSTQGSFTGHPKKTNGNNGTNGALVQSPSNQSALGAGGTNGNGGVARVWGVATGSSSGLTHCSVGGGDGKMDNMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGSQNGNPVGTVGAWGNLLPQESTEPQTSTCQNVSFSVQPQNLNTDGSNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQGSGSGGEGMGSSVWGLSPGNPATGNNNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGNGGNAWDSGPPAGPGILAWGRGSGNNGIGNIHSGAWGHPSRSSSNGMNGEWGKLPNQHSSSDISGKGSTGWDSPSAASQPPALQPGSEHVSSWAKATSSGTTPSEGSSDGSGHHSEGGAGREAMGEGRRRDQGHIQLPRGDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGSAATQPSNSGGKSDGSLMNSTNTSSVSGWVSSPPAAVPANTSWGDSNNKAPSGPGVWGDSISSTAVNNAAATKSGHAWSGTVNQEDKSPTWGEPQKPKSQNWGDGQRANPAWSAGAGDWADSSSVLGHLGDGKKNGPGWDADGNRSGSGWNDASRCGTSGWASGASAKVNPGTNWGESLKPGPQQSWAHKPQDSNVSNWGGAASVKQTGTGWIGGPLPVKQKDSCEATGWEEPSPPSIRRKMEIDDGTSAWGDPSTYNNKTVNMWDRNNPVIQSSTTTPATPTTPTSSSTTHQAETPPSHQAGTQLNRSPLLGPVSSGWGEMPSVHSKAENSWGEPSSPSPLVDNGTAAWGKPPSSGSGWDHPAEPVVPFGRASAPAAAPALCKPASKSMQEGWGSGGDEMNLGASQWEDEDGDMWNNGVSQEGSSSCSSWGNASKKGLQKGMKTPGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNSMNLDQAMSALLEKKVDMDKRGLGMTDYNGMVTKTLGCRPPISKESSMDRPTFLDKVQAQLLQFAAKNIGLSPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGPMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPPHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSIDVSSGLSVKDSSQSQSRLPQWTHPNSMGNLSSAASPLDQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSISWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPASHTQASLSHELWKVPRNTTAPTRPPPGLANPKPSSTWGTSPLGWTSSYSSGSAWSTDASGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQPSSGGSQPRLGSSGSTHGLVRSDTAHWSTPCLSGKGSSELLWGGVPQYSSSLWGPPSADDARVIGSPTPLNTLLPGDLLSGESM", "length": 1784, "header": "tr|A0A9J7H4B8-1|A0A9J7H4B8_CRIGR Computationally mapped isoform of Trinucleotide repeat-containing gene 6C protein OS=Cricetulus griseus OX=10029 GN=Tnrc6c PE=3 SV=1 CANONICAL=A0A9J7GAV4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAH5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAH5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770135", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770135", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4" } ], "pmid": "" }, { "name": "P-body", "id": "GO:0000932", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000932", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4" } ], "pmid": "" }, { "name": "positive regulation of nuclear-transcribed mRNA poly(A) tail shortening", "id": "GO:0060213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060213", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4" } ], "pmid": "" }, { "name": "miRNA-mediated post-transcriptional gene silencing", "id": "GO:0035195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035195", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1023, "end_pos": 1025, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1111, "end_pos": 1113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1259, "end_pos": 1261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1292, "end_pos": 1294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1366, "end_pos": 1368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1498, "end_pos": 1500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1569, "end_pos": 1571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1611, "end_pos": 1613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1657, "end_pos": 1659, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1710, "end_pos": 1712, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1736, "end_pos": 1738, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1766, "end_pos": 1768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 822, "end_pos": 824, "annotation": "n_glycosylation_sequon" }, { "start_pos": 873, "end_pos": 875, "annotation": "n_glycosylation_sequon" }, { "start_pos": 937, "end_pos": 939, "annotation": "n_glycosylation_sequon" }, { "start_pos": 985, "end_pos": 987, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GAV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV4" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 1126, "end_pos": 1171, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1023, "end_pos": 1025 }, { "start_pos": 1111, "end_pos": 1113 }, { "start_pos": 1259, "end_pos": 1261 }, { "start_pos": 1292, "end_pos": 1294 }, { "start_pos": 1366, "end_pos": 1368 }, { "start_pos": 1498, "end_pos": 1500 }, { "start_pos": 1569, "end_pos": 1571 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automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027281392.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281392" } ] }, { "annotation": "E3 ubiquitin ligase.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6#function" }, { "database": "UniProtKB", "id": "RU369081", "url": "https://www.uniprot.org/uniprotkb/RU369081#function" }, { "database": "UniProtKB", "id": "A0A9J7GF84", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF84#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rnf157", "url": 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26192", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26192", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281392", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GF84", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GF84-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A9J7GAJ6/entry#A0A9J7GAJ6-1", "sequence": { "sequence": "MVRAPQAAAARPRRPAAAPPPSGPPTPASGVRPGGRRAEARRAEPGDAAVAAAMGALTSRQHAGVEEVDIPSNSVYRYPPKSGSYFASHFIMGGEKFDSTHPEGYLFGENSDLNFLGNRPVAFPYAAPPPQEPVKTLRSLINIRKDTLRLVKCAEEVKSHGEEAGKAKVHYNVEFTFDTDARVAITIYYQATEEFQNGIASYIPKDNSLQSETVHYKRGVCQQFCLPSHTVDPSEWAEEELGFDLDREVYPLVVHAVVDEGDEYFGHCHVLLGTFEKHTDGTFCVKPLKQKQVVDGVSYLLQEIYGIENKYNTQDSKVAEDEGSDNSAECVVCLSDVRDTLILPCRHLCLCNTCADTLRYQANNCPICRLPFRALLQIRAMRKKLGPLSPTSFNPIISSQTSDSEEHSSSENIPPGYEVVSLLEALNGPLTPSPAVPPLHVLGDGHLSGMLPSYGSDDHLPPMRTVSPLDRLSDCSNQGLKLKKSLSKSVSQNSSVLHEEEDERSYSESETQLSQRLSAQHPEEGRDVTPESENLTLSSSGAVGQSSCTGTPLSSTISSPEDPASSSLAQSVMSMASSQISTDTVSSMSGSYIAPGTEEEGEALPSPLAASRAPSEGEGTPAESPDSNFAGLPAGEQDAEGNDIVEEEDRSPVQEDGQRTCAFLGMECDNNNDFDIASVKALDNKLCSEVCLPGAWQHDDNIVNRHNTRCRHSSSSSLEDPEENRPCVWDPLAV", "length": 734, "header": "tr|A0A9J7GAJ6-1|A0A9J7GAJ6_CRIGR Isoform 1 of E3 ubiquitin-protein ligase OS=Cricetulus griseus OX=10029 GN=Rnf157 PE=4 SV=1 CANONICAL=A0A9J7GAJ6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GF84-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6/entry#A0A9J7GF84-1", "sequence": { "sequence": "MVRAPQAAAARPRRPAAAPPPSGPPTPASGVRPGGRRAEARRAEPGDAAVAAAMGALTSRQHAGVEEVDIPSNSVYRYPPKSGSYFASHFIMGGEKFDSTHPEGYLFGENSDLNFLGNRPVAFPYAAPPPQEPVKTLRSLINIRKDTLRLVKCAEEVKSHGEEAGKAKVHYNVEFTFDTDARVAITIYYQATEEFQNGIASYIPKDNSLQSETVHYKRGVCQQFCLPSHTVDPSEWAEEELGFDLDREVYPLVVHAVVDEGDEYFGHCHVLLGTFEKHTDGTFCVKPLKQKQVVDGVSYLLQEIYGIENKYNTQDSKVAEDEGSDNSAECVVCLSDVRDTLILPCRHLCLCNTCADTLRYQANNCPICRLPFRALLQIRAMRKKLGPLSPTSFNPIISSQTSDSEEHSSSENIPPGYEVVSLLEALNGPLTPSPAVPPLHVLGDGHLSGMLPSYGSDDHLPPMRTVSPLDRLSDCSNQGLKLKKSLSKSVSQNSSVLHEEEDERSYSESETQLSQRLSAQHPEEGRDVTPESENLTLSSSGAVGQSSCTGTPLSSTISSPEDPASSSLAQSVMSMASSQISTDTVSSMSGSYIAPGTEEEGEALPSPLAASRAPSEGEGTPAESPDSNFAGLPAGEQDAEGNDIVEEEDRSPVQEDGQRTCAFLGMECDNNNDFDIASVKALDNKLCSEVCLPAAAPESCPINIEE", "length": 706, "header": "tr|A0A9J7GF84-1|A0A9J7GF84_CRIGR Computationally mapped isoform of E3 ubiquitin-protein ligase OS=Cricetulus griseus OX=10029 GN=Rnf157 PE=4 SV=1 CANONICAL=A0A9J7GAJ6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 26, "start_aa": "Thr", "end_pos": 26, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr26", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760898", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760898", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GAJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAJ6" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 330, "end_pos": 369, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 26 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 493, "end_pos": 495 }, { "start_pos": 534, "end_pos": 536 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GAK6-1", "uniprot_ac": "A0A9J7GAK6", "uniprot_id": "A0A9J7GAK6_CRIGR", "mass": { "chemical_mass": 139233.0, "monoisotopic_mass": 139233.0 }, "refseq": { "ac": "XP_016833254", "name": "fas-binding factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833254" }, "gene_names": [ { "name": "Fbf1", "type": "recommended", "evidence": [ { "id": "A0A9J7GAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ] }, { "name": "Fbf1", "type": "synonym", "evidence": [ { "id": "XP_016833254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833254" } ] } ], "protein_names": [ { "name": "Fas-binding factor 1 isoform X15", "type": "synonym", "evidence": [ { "id": "A0A9J7GAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#names_and_taxonomy" } ] }, { "name": "fas-binding factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016833254", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833254" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614300.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016833254", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833254" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fbf1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6", "locus": {} } ], "crossref": [ { "id": "A0A9J7GAK6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GAK6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100758866", "url": "https://www.ncbi.nlm.nih.gov/gene/100758866", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033561", 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}, { "id": "A0A9J7GDK3", "url": "https://www.orthodb.org/?gene=A0A9J7GDK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GDM6", "url": "https://www.orthodb.org/?gene=A0A9J7GDM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GF97", "url": "https://www.orthodb.org/?gene=A0A9J7GF97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GGC8", "url": "https://www.orthodb.org/?gene=A0A9J7GGC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H3M3", "url": "https://www.orthodb.org/?gene=A0A9J7H3M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JXZ4", "url": "https://www.orthodb.org/?gene=A0A9J7JXZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33689", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33689", "database": "PANTHER", "categories": [ "Protein 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0A5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1Z3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4A3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4A3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXZ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVKTRRSSRTRGPSQAAPRKRRTPREAATGCLGDPEDPWRDTSQRPLDLQVAAVAIAREKHKHPPCVLNPRNTVHCGKRLDTPGRQMRAAAAFLPRHAKALKTKKGLKGSIDDVLGDLLGDDTALLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1256, "header": "tr|A0A9J7GAK6-1|A0A9J7GAK6_CRIGR Isoform 1 of Fas-binding factor 1 isoform X15 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MPK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A8C2MPK6-1", "sequence": { "sequence": "MALKTKKGLKGSIDDVLGDLLGDDTLLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1156, "header": "tr|A0A8C2MPK6-1|A0A8C2MPK6_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X26 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7GAK6-1", "sequence": { "sequence": "MGVKTRRSSRTRGPSQAAPRKRRTPREAATGCLGDPEDPWRDTSQRPLDLQVAAVAIAREKHKHPPCVLNPRNTVHCGKRLDTPGRQMRAAAAFLPRHAKALKTKKGLKGSIDDVLGDLLGDDTALLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1256, "header": "tr|A0A9J7GAK6-1|A0A9J7GAK6_CRIGR Isoform 1 of Fas-binding factor 1 isoform X15 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7GBR5-1", "sequence": { "sequence": "MRAAAAFLPRHAKALKTKKGLKGSIDDVLGDLLGDDTALLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1169, "header": "tr|A0A9J7GBR5-1|A0A9J7GBR5_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X24 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7GBT2-1", "sequence": { "sequence": "MSPAPRSLQLPLRGRNTSTPPASSTPETLCTVALKTKKGLKGSIDDVLGDLLGDDTALLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1188, "header": "tr|A0A9J7GBT2-1|A0A9J7GBT2_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X23 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7GBU8-1", "sequence": { "sequence": "MALKTKKGLKGSIDDVLGDLLGDDTALLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1157, "header": "tr|A0A9J7GBU8-1|A0A9J7GBU8_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X25 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7GDK3-1", "sequence": { "sequence": "MGVKTRRSSRTRGPSQAAPRKRRTPREAATGCLGDPEDPWRDTSQRPLDLQVAAVAIAREKHKHPPCVLNPRNTVHCGKRLDTPGRQMRAAAAFLPRHAKALKTKKGLKGSIDDVLGDLLGDDTALLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1239, "header": "tr|A0A9J7GDK3-1|A0A9J7GDK3_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X18 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7GDM6-1", "sequence": { "sequence": "MSPAPRWSLQLPLRGRNTSTPPASSTPETLCTVALKTKKGLKGSIDDVLGDLLGDDTALLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1189, "header": "tr|A0A9J7GDM6-1|A0A9J7GDM6_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X19 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GF97-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7GF97-1", "sequence": { "sequence": "MGVKTRRSSRTRGPSQAAPRKRRTPREAATGCLGDPEDPWRDTSQRPLDLQVAAVAIAREKHKHPPCVLNPRNTVHCGKRLDTPGRQMRAAAAFLPRHAKALKTKKGLKGSIDDVLGDLLGDDTLLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1255, "header": "tr|A0A9J7GF97-1|A0A9J7GF97_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X16 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GGC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7GGC8-1", "sequence": { "sequence": "MSPAPRWSLQLPLRGRNTSTPPASSTPETLCTVALKTKKGLKGSIDDVLGDLLGDDTLLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1188, "header": "tr|A0A9J7GGC8-1|A0A9J7GGC8_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X21 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H0A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7H0A5-1", "sequence": { "sequence": "MDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1065, "header": "tr|A0A9J7H0A5-1|A0A9J7H0A5_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X28 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7H1Z3-1", "sequence": { "sequence": "MGVTQVVSHHVGTENPTWLLRKSNKCPKWPRLQALKTKKGLKGSIDDVLGDLLGDDTLLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1188, "header": "tr|A0A9J7H1Z3-1|A0A9J7H1Z3_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X22 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7H3M3-1", "sequence": { "sequence": "MKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1071, "header": "tr|A0A9J7H3M3-1|A0A9J7H3M3_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X27 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7H4A3-1", "sequence": { "sequence": "MGVTQVVSHHVGTENPTWLLRKSNKCPKWPRLQALKTKKGLKGSIDDVLGDLLGDDTALLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVNRFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1189, "header": "tr|A0A9J7H4A3-1|A0A9J7H4A3_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X20 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6/entry#A0A9J7JXZ4-1", "sequence": { "sequence": "MGVKTRRSSRTRGPSQAAPRKRRTPREAATGCLGDPEDPWRDTSQRPLDLQVAAVAIAREKHKHPPCVLNPRNTVHCGKRLDTPGRQMRAAAAFLPRHAKALKTKKGLKGSIDDVLGDLLGDDTALLEKPVEPASHAKDTASVPQWPPSKAKGRSLPKDSVDGLLGADAEVSSISDADPQVFLQNMKDLDSMDDDLFGRMKSHPPSGKGTTKGSGKEVPSNPKPAGALTANDKGDAIPAKKSPPPSSNYGLQYKKFSFEDFEDPLAGLLSDEEEETAKKPPTMESKPVSKSPSTATGHQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKEERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFKLDKKYQKPEDKEDSWDDEILTFGAYQPTVASSEGRQSRRQSVKFLGEGGSDLKGDLKGEAGFRHSPPPASSPAHPRRGGADWLGLKDDDLDLLSSSPVQKVQQEDSAISTPSLPPPINQHSAPEPHPAPVGLPSAAKPAAKGVRPSTKASQASLKASEEKEDDWLSHVISQKKSQGLAREDRAEPSKGLNSRGSLGQTPSSSQSVAGTQALEQAIAEEASRTIPQGIAAGRPGITGSSMRWSQATTVLPVGDPKTGMVSASGDFSSREPALYVPRSQEPTGLSVPIQPLLPESVVQSLLPGSGYQKQLLAAQGQLQGSTAQLQAELLQSQTKLSELEAQVRKLELERTQHRVLLESLQQRHQADLALIEDAHRSRVKVLEASYQQREEQLLREKEALSAQHASYCREAEQARAELIAQHQRHLAMAAQEKDQEVARLRELQQASILEMRKDHEHQLQRLKVLKDQEIDAVTSATSHTRSLNGIIEQMERFSSSLTVLSSRVEASHLNTSQERELGIRQQDEQLRALQERLGRQQRDMEEERSRLQEVIGKMEVRLSEQSRLLEQERWQVATEKSKAESAQRTLEEQRRLMVQQISMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERALHADSQREDTIISLTKEQAELTVRACELRAKEEKLAAEREALERERQELRLEKDRLHKASLRLQARVQEVEHMSKVASKKYEEGEQALQEAQQMQSEQQGRLQAVQRQQEWLRQQEQRMHKEHLSLAQQRLQLDRVRQEVPSSLLGQPSTVQGPAVPSLDAVQAPAPTSPQCSQTPAAPVPTHLLAKLLLLKHTAAQDHDFLENEQFFLETLKKAPYNMAYHSA", "length": 1255, "header": "tr|A0A9J7JXZ4-1|A0A9J7JXZ4_CRIGR Computationally mapped isoform of Fas-binding factor 1 isoform X17 OS=Cricetulus griseus OX=10029 GN=Fbf1 PE=4 SV=1 CANONICAL=A0A9J7GAK6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1200, "start_aa": "Thr", "end_pos": 1200, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1200", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758866", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758866", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "pmid": "" }, { "name": "establishment of epithelial cell polarity", "id": "GO:0090162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090162", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "pmid": "" }, { "name": "apical junction assembly", "id": "GO:0043297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043297", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "pmid": "" }, { "name": "ciliary transition fiber", "id": "GO:0097539", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097539", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "pmid": "" }, { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "pmid": "" }, { "name": "keratin filament", "id": "GO:0045095", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GAK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAK6" }, { "id": "PF21007", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21007" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fas-binding factor 1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 724, "end_pos": 1246, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1200 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 888, "end_pos": 890 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GAP7-1", "uniprot_ac": "A0A9J7GAP7", "uniprot_id": "A0A9J7GAP7_CRIGR", "mass": { "chemical_mass": 110202.0, "monoisotopic_mass": 110202.0 }, "refseq": { "ac": "XP_027280579", "name": "zinc finger CCCH domain-containing protein 7A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280579" }, "gene_names": [ { "name": "Zc3h7a", "type": "recommended", "evidence": [ { "id": "A0A9J7GAP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7" } ] }, { "name": "Zc3h7a", "type": "synonym", "evidence": [ { "id": "XP_027280579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280579" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH domain-containing protein 7A isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7GAP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCCH domain-containing protein 7A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027280579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280579" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280579" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zc3h7a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7", "locus": {} } ], "crossref": [ { "id": "100770208", "url": "https://www.ncbi.nlm.nih.gov/gene/100770208", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770208", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770208", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GAP7", "url": "https://www.orthodb.org/?gene=A0A9J7GAP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14928", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14928", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14928:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14928:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280579", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GAP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H404", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H404", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H404-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H404-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXA8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSVSEERRKRQHNIKEGLQFIQSPLSYPGTQEQYAVYLQDLVRNLFNEGNDIYRECDWSSSLSQYSEALSIADYAKSEEILMPQEIIEKLHINRIACYSNMGFHDKVLEDCNAVLSVNASNCKALYRKSKALSDLGRYGEAYDAVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAELSLKPVPGAGVTKAVNYSVEDIEPDLLTPKQEALPVVSLPTSSFSHDIGSELTSVSGMPVTSVLQLQVDESPLPSTMFANGGKIPFTLPDAFVDDGDIILGDDIDDLLDSAPETNDGIMPSTLGRGSLPTASVAPSLPFRTTSLLGTLPIGARYAPPPSFAELYPPLTSALEDFCSSLNSFSVTESKRDLSTSTAREGTTLNNSNSSLLLMNGPGSLFPSENFLGIASQPRNDFGNLFGSVIAKPFSSGTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANLDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEDECRYSGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKISLTVVKLLQEHLGEFTFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILRETTVKYSKIRSFHSQCQLDLCRHEVRYGCLREDECFYAHSLIELKVWIMQNERGISHDVIAQESQQYWRSLEASMPGAQVLGNQIMPGLLNMEIKFVCAQCLRNGQVIEPDKNRKYCSAKAQHSWTKERRAMRAMSFERKKWMNIRPLPTKKQMPLQFDLCNHIASGKKCQYVGNCSFAHSPEEREVWTYMKDNKIHDIEQFYELWLKNQKSEKSDDVASHANKENGKQIHMPTDYAEITVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQYCWQHRFPTGNFSICERYMNGSCTEGSSCKFAHGSAELHEWKERRKALEMKLNKARKDHLIAPNDNDFGKYSFLFKDLN", "length": 972, "header": "tr|A0A9J7GAP7-1|A0A9J7GAP7_CRIGR Isoform 1 of Zinc finger CCCH domain-containing protein 7A isoform X1 OS=Cricetulus griseus OX=10029 GN=Zc3h7a PE=4 SV=1 CANONICAL=A0A9J7GAP7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GAP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7/entry#A0A9J7GAP7-1", "sequence": { "sequence": "MSSVSEERRKRQHNIKEGLQFIQSPLSYPGTQEQYAVYLQDLVRNLFNEGNDIYRECDWSSSLSQYSEALSIADYAKSEEILMPQEIIEKLHINRIACYSNMGFHDKVLEDCNAVLSVNASNCKALYRKSKALSDLGRYGEAYDAVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAELSLKPVPGAGVTKAVNYSVEDIEPDLLTPKQEALPVVSLPTSSFSHDIGSELTSVSGMPVTSVLQLQVDESPLPSTMFANGGKIPFTLPDAFVDDGDIILGDDIDDLLDSAPETNDGIMPSTLGRGSLPTASVAPSLPFRTTSLLGTLPIGARYAPPPSFAELYPPLTSALEDFCSSLNSFSVTESKRDLSTSTAREGTTLNNSNSSLLLMNGPGSLFPSENFLGIASQPRNDFGNLFGSVIAKPFSSGTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANLDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEDECRYSGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKISLTVVKLLQEHLGEFTFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILRETTVKYSKIRSFHSQCQLDLCRHEVRYGCLREDECFYAHSLIELKVWIMQNERGISHDVIAQESQQYWRSLEASMPGAQVLGNQIMPGLLNMEIKFVCAQCLRNGQVIEPDKNRKYCSAKAQHSWTKERRAMRAMSFERKKWMNIRPLPTKKQMPLQFDLCNHIASGKKCQYVGNCSFAHSPEEREVWTYMKDNKIHDIEQFYELWLKNQKSEKSDDVASHANKENGKQIHMPTDYAEITVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQYCWQHRFPTGNFSICERYMNGSCTEGSSCKFAHGSAELHEWKERRKALEMKLNKARKDHLIAPNDNDFGKYSFLFKDLN", "length": 972, "header": "tr|A0A9J7GAP7-1|A0A9J7GAP7_CRIGR Isoform 1 of Zinc finger CCCH domain-containing protein 7A isoform X1 OS=Cricetulus griseus OX=10029 GN=Zc3h7a PE=4 SV=1 CANONICAL=A0A9J7GAP7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H404-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7/entry#A0A9J7H404-1", "sequence": { "sequence": "MSSVSEERRKRQHNIKEGLQFIQSPLSYPGTQEQYAVYLQDLVRNLFNEGNDIYRECDWSSSLSQYSEALSIADYAKSEEILMPQEIIEKLHINRIACYSNMGFHDKVLEDCNAVLSVNASNCKALYRKSKALSDLGRYGEAYDAVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAELSLKPVPGAGVTKAVNYSVEDIEPDLLTPKQEALPVVSLPTSSFSHDIGSELTSVSGMPVTSVLQLQVDESPLPSTMFANGGKIPFTLPDAFVDDGDIILGDDIDDLLDSAPETNDGIMPSTLGRGSLPTASVAPSLPFRTTSLLGTLPIGARYAPPPSFAELYPPLTSALEDFCSSLNSFSVTESKRDLSTSTAREGTTLNNSNSSLLLMNGPGSLFPSENFLGIASQPRNDFGNLFGSVIAKPFSSGTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANLDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEDECRYSGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKISLTVVKLLQEHLGEFTFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILRETTVKYSKIRSFHSQCQLDLCRHEVRYGCLREDECFYAHSLIELKVWIMQNERGISHDVIAQESQQYWRSLEASMPGAQVLGNQIMPGLLNMEIKFVCAQCLRNGQVIEPDKNRKYCSAKAQHSWTKERRAMRAMSFEPMQPYCFWKKMSVCWQLFLCS", "length": 774, "header": "tr|A0A9J7H404-1|A0A9J7H404_CRIGR Computationally mapped isoform of Zinc finger CCCH domain-containing protein 7A isoform X3 OS=Cricetulus griseus OX=10029 GN=Zc3h7a PE=4 SV=1 CANONICAL=A0A9J7GAP7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7/entry#A0A9J7JXA8-1", "sequence": { "sequence": "MPQEIIEKLHINRIACYSNMGFHDKVLEDCNAVLSVNASNCKALYRKSKALSDLGRYGEAYDAVAKCSLAVPQDEHVIKLTQELAQKLGFKIRKAYVRAELSLKPVPGAGVTKAVNYSVEDIEPDLLTPKQEALPVVSLPTSSFSHDIGSELTSVSGMPVTSVLQLQVDESPLPSTMFANGGKIPFTLPDAFVDDGDIILGDDIDDLLDSAPETNDGIMPSTLGRGSLPTASVAPSLPFRTTSLLGTLPIGARYAPPPSFAELYPPLTSALEDFCSSLNSFSVTESKRDLSTSTAREGTTLNNSNSSLLLMNGPGSLFPSENFLGIASQPRNDFGNLFGSVIAKPFSSGTPRHPLEGTHELRQACQICFVKSGPKLMDFTYHANLDHKCKKDILIGRIKNVEDKSWKKIRPRPTKTNYEGPYYICKDVAAEDECRYSGHCTFAYCQEEIDVWTLERKGAFSREAFFGGNGKISLTVVKLLQEHLGEFTFLCEKCFDHKPRMISKRNKDNSTACSHPVTKHEFEDNKCLVHILRETTVKYSKIRSFHSQCQLDLCRHEVRYGCLREDECFYAHSLIELKVWIMQNERGISHDVIAQESQQYWRSLEASMPGAQVLGNQIMPGLLNMEIKFVCAQCLRNGQVIEPDKNRKYCSAKAQHSWTKERRAMRAMSFERKKWMNIRPLPTKKQMPLQFDLCNHIASGKKCQYVGNCSFAHSPEEREVWTYMKDNKIHDIEQFYELWLKNQKSEKSDDVASHANKENGKQIHMPTDYAEITVDFHCWMCGKNCNSEKQWQGHISSEKHKEKVFHTEDDQYCWQHRFPTGNFSICERYMNGSCTEGSSCKFAHGSAELHEWKERRKALEMKLNKARKDHLIAPNDNDFGKYSFLFKDLN", "length": 890, "header": "tr|A0A9J7JXA8-1|A0A9J7JXA8_CRIGR Computationally mapped isoform of Zinc finger CCCH domain-containing protein 7A isoform X2 OS=Cricetulus griseus OX=10029 GN=Zc3h7a PE=4 SV=1 CANONICAL=A0A9J7GAP7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770208", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770208", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7" } ], "pmid": "" }, { "name": "miRNA binding", "id": "GO:0035198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035198", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7" } ], "pmid": "" }, { "name": "miRNA processing", "id": "GO:0035196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035196", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 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This record is derived from a genomic sequence (NW_003613631.1) and transcript sequence (IACG01049764.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016836030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836030" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Clec16a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0", "locus": {} } ], "crossref": [ { "id": "A0A9J7GAQ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GAQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768590", "url": "https://www.ncbi.nlm.nih.gov/gene/100768590", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039272", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039272", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045820", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045820", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768590", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768590", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GAQ0", "url": "https://www.orthodb.org/?gene=A0A9J7GAQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GAQ7", "url": "https://www.orthodb.org/?gene=A0A9J7GAQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JVU0", "url": "https://www.orthodb.org/?gene=A0A9J7JVU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21481", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21481", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21481:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21481:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016836030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836030", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LHM5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LHM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVU0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXB3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGRSRSWVGGGHGKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENPEKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYTKPAQDVPRSSAKPSIRCFIKPTETLERSLEMNKHKGKKRMQKRPNYKNVGEEEDEERGPAEDAQEDAEKAKGTEGGSKSMKTSGEREEIEMVIMERSKLSELATAGASVREQNTTDEEKSAATGSESTQLSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLKRIQLPVPSAAEKTTYNHLLAERLIRIMNNAAQPDGRIRLATLELSCLLLKQQVLTRSGCIIKDVHLACLEGAREESVHLVRHFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRREKFPEAEFLIQRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGLVQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLSNSSSQHLPFRFYDQCRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSPSLSSPSPPSASGSPGGSGSTSHYDSGGSSSTPSAAQSPADAPTTPEQPQPHLLDQSVIVNEMDVNSKPSKNLARSSEVETMHLAPSLLPAQQPTISLLYEDTADTLSVESLTLVPPVDPHSLRALTGIPQNSTLAAAGTETPDEDTVYPESASPTEH", "length": 1060, "header": "tr|A0A9J7GAQ0-1|A0A9J7GAQ0_CRIGR Isoform 1 of Protein CLEC16A isoform X1 OS=Cricetulus griseus OX=10029 GN=Clec16a PE=3 SV=1 CANONICAL=A0A9J7GAQ0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LHM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0/entry#A0A8C2LHM5-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENPEKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYTKPAQDVPRSSAKPSIRCFIKPTETLERSLEMNKHKGKKRMQKRPNYKNVGEEEDEERGPAEDAQEDAEKAKEIEMVIMERSKLSELATAGASVREQNTTDEEKSAATGSESTQLSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLKRIQLPVPSAAEKTTYNHLLAERLIRIMNNAAQPDGRIRLATLELSCLLLKQQVLTRSGCIIKDVHLACLEGAREESVHLVRHFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGLVQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLSNSSSQHLPFRFYDQCRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSPSLSSPSPPSASGSPGGSGSTSHYDSGGSSSTPSAAQSPADAPTTPEQPQPHLLDQSVIVNEMDVNSKPSKNLARSSEVETMHLAPSLLPAQQPTISLLYEDTADTLSVESLTLVPPVDPHSLRALTGIPQNSTLAAAGTETPDEDTVYPESASPTEH", "length": 1032, "header": "tr|A0A8C2LHM5-1|A0A8C2LHM5_CRIGR Computationally mapped isoform of Protein CLEC16A isoform X4 OS=Cricetulus griseus OX=10029 GN=Clec16a PE=3 SV=1 CANONICAL=A0A9J7GAQ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0/entry#A0A9J7GAQ0-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENPEKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYTKPAQDVPRSSAKPSIRCFIKPTETLERSLEMNKHKGKKRMQKRPNYKNVGEEEDEERGPAEDAQEDAEKAKGTEGGSKSMKTSGEREEIEMVIMERSKLSELATAGASVREQNTTDEEKSAATGSESTQLSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLKRIQLPVPSAAEKTTYNHLLAERLIRIMNNAAQPDGRIRLATLELSCLLLKQQVLTRSGCIIKDVHLACLEGAREESVHLVRHFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRREKFPEAEFLIQRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGLVQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLSNSSSQHLPFRFYDQCRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSPSLSSPSPPSASGSPGGSGSTSHYDSGGSSSTPSAAQSPADAPTTPEQPQPHLLDQSVIVNEMDVNSKPSKNLARSSEVETMHLAPSLLPAQQPTISLLYEDTADTLSVESLTLVPPVDPHSLRALTGIPQNSTLAAAGTETPDEDTVYPESASPTEH", "length": 1060, "header": "tr|A0A9J7GAQ0-1|A0A9J7GAQ0_CRIGR Isoform 1 of Protein CLEC16A isoform X1 OS=Cricetulus griseus OX=10029 GN=Clec16a PE=3 SV=1 CANONICAL=A0A9J7GAQ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0/entry#A0A9J7GAQ7-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENPEKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYTKPAQDVPRSSAKPSIRCFIKPTETLERSLEMNKHKGKKRMQKRPNYKNVGEEEDEERGPAEDAQEDAEKAKEIEMVIMERSKLSELATAGASVREQNTTDEEKSAATGSESTQLSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLKRIQLPVPSAAEKTTYNHLLAERLIRIMNNAAQPDGRIRLATLELSCLLLKQQVLTRSGCIIKDVHLACLEGAREESVHLVRHFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRREKFPEAEFLIQRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGLVQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLSNSSSQHLPFRFYDQCRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSPSLSSPSPPSASGSPGGSGSTSHYDSGGSSSTPSAAQSPADAPTTPEQPQPHLLDQSVIVNEMDVNSKPSKNLARSSEVETMHLAPSLLPAQQPTISLLYEDTADTLSVESLTLVPPVDPHSLRALTGIPQNSTLAAAGTETPDEDTVYPESASPTEH", "length": 1044, "header": "tr|A0A9J7GAQ7-1|A0A9J7GAQ7_CRIGR Computationally mapped isoform of Protein CLEC16A isoform X3 OS=Cricetulus griseus OX=10029 GN=Clec16a PE=3 SV=1 CANONICAL=A0A9J7GAQ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0/entry#A0A9J7JVU0-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENPEKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYTKPAQDVPRSSAKPSIRCFIKPTETLERSLEMNKHKGKKRMQKRPNYKNVGEEEDEERGPAEDAQEDAEKAKGTEGGSKSMKTSGEREEIEMVIMERSKLSELATAGASVREQNTTDEEKSAATGSESTQLSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLKRIQLPVPSAAEKTTYNHLLAERLIRIMNNAAQPDGRIRLATLELSCLLLKQQVLTRSGCIIKDVHLACLEGAREESVHLVRHFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRREKFPEAEFLIQRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGLVQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLSNSSSQHLPFRFYDQCRRGSSDPTVQRSVFASVDKVPGFHV", "length": 893, "header": "tr|A0A9J7JVU0-1|A0A9J7JVU0_CRIGR Computationally mapped isoform of Protein CLEC16A isoform X6 OS=Cricetulus griseus OX=10029 GN=Clec16a PE=3 SV=1 CANONICAL=A0A9J7GAQ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0/entry#A0A9J7JXB3-1", "sequence": { "sequence": "MFGRSRSWVGGGHGKSSRNIHSLDHLKYLYHVLTKNTTVTEQNRNLLVETIRSITEILIWGDQNDSSVFDFFLEKNMFVFFLNILRQKSGRYVCVQLLQTLNILFENISHETSLYYLLSNNYVNSIIVHKFDFSDEEIMAYYISFLKTLSLKLNNHTVHFFYNEHTNDFALYTEAIKFFNHPESMVRIAVRTITLNVYKVDNQAMLHYIRDKTAVPYFSNLVWFIGSHVIELDNCVQTDEEHRNRGKLSDLVAEHLDHLHYLNDILIINCEFLNDVLTDHLLNRLFLPLYVYSLENPEKGGERPKISLPVSLYLLSQVFLIIHHAPLVNSLAEVILNGDLSETYTKPAQDVPRSSAKPSIRCFIKPTETLERSLEMNKHKGKKRMQKRPNYKNVGEEEDEERGPAEDAQEDAEKAKGTEGGSKSMKTSGEREEIEMVIMERSKLSELATAGASVREQNTTDEEKSAATGSESTQLSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLKRIQLPVPSAAEKTTYNHLLAERLIRIMNNAAQPDGRIRLATLELSCLLLKQQVLTRSGCIIKDVHLACLEGAREESVHLVRHFYKGEEIFLDMFEDEYRSMTIKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPCGDVEKTRREKFPEAEFLIQRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGLVQRFLAVDIYQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFVFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEVLGFGLSNSSSQHLPFRFYDQCRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSPSLSSPSPPSASGSPGGSGSTSHYDSGGSSSTPSAAQSPAVRNGRKGRRRVFSLSEADSHGGHWV", "length": 967, "header": "tr|A0A9J7JXB3-1|A0A9J7JXB3_CRIGR Computationally mapped isoform of Protein CLEC16A isoform X5 OS=Cricetulus griseus OX=10029 GN=Clec16a PE=3 SV=1 CANONICAL=A0A9J7GAQ0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 934, "start_aa": "Thr", "end_pos": 934, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr934", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768590", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768590", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0" } ], "pmid": "" }, { "name": "regulation of autophagosome maturation", "id": "GO:1901096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ0" } ], "pmid": "" }, { "name": "late endosome", "id": "GO:0005770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", "evidence": [ { 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MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280713" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAV7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rnps1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV7", "locus": {} } ], "crossref": [ { "id": "A0A9J7GAV7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GAV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12365", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12365", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100689458", "url": "https://www.ncbi.nlm.nih.gov/gene/100689458", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15481", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15481", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15481:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15481:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280713", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MNA0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MNA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAV7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWPEQTVPIVNRPKRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSSR", "length": 296, "header": "tr|A0A9J7GAV7-1|A0A9J7GAV7_CRIGR Isoform 1 of RNA-binding protein with serine-rich domain 1 OS=Cricetulus griseus OX=10029 GN=Rnps1 PE=3 SV=1 CANONICAL=A0A9J7GAV7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MNA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV7/entry#A0A8C2MNA0-1", "sequence": { "sequence": "MAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSSR", "length": 282, "header": "tr|A0A8C2MNA0-1|A0A8C2MNA0_CRIGR Computationally mapped isoform of RNA-binding protein with serine-rich domain 1 OS=Cricetulus griseus OX=10029 GN=Rnps1 PE=3 SV=1 CANONICAL=A0A9J7GAV7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV7/entry#A0A9J7GAV7-1", "sequence": { "sequence": "MWPEQTVPIVNRPKRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKALKHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPGRRRHRSRSSSNSSR", "length": 296, "header": "tr|A0A9J7GAV7-1|A0A9J7GAV7_CRIGR Isoform 1 of RNA-binding protein with serine-rich domain 1 OS=Cricetulus griseus OX=10029 GN=Rnps1 PE=3 SV=1 CANONICAL=A0A9J7GAV7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GAV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAV7" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 152, "end_pos": 231, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 293, "end_pos": 295 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"XP_027281659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281659" } ] } ], "protein_names": [ { "name": "Forkhead box protein K2", "type": "recommended", "evidence": [ { "id": "A0A9J7GAX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAX0/entry#names_and_taxonomy" } ] }, { "name": "Interleukin enhancer-binding factor 1", "type": "synonym", "evidence": [ { "id": "A0A9J7GAX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAX0/entry#names_and_taxonomy" } ] }, { "name": "forkhead box protein K2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027281659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281659" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027281659.1. 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279414" } ] }, { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAX6#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAX6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772267", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAX6", "locus": {} } ], "crossref": [ { "id": "A0A9J7GAX6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GAX6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15235", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15235", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772267", "url": "https://www.ncbi.nlm.nih.gov/gene/100772267", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772267", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772267", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GAX6", "url": "https://www.orthodb.org/?gene=A0A9J7GAX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279414", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GAX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVWHQYKKPPYTTLEQEYLLRAAILRENQSHMTEFLLLGLTSDPKQQVWLFAGFLAMYLANVIGNSVIIAAIRGDTHLHTPMYFFLSNLSLVDICFTTVIVPQMLVNLLTQRKTILFTQCLAQMYFFVAFGITDSFLLAAMAIDRYVAICNPLHYTTTMSPRRCRLLVMVSWAVSHLHSLTHTILMGRLSFCGANVIHHFFCDVQPLLTLSCSDTSINELLAFTEGSIVIMSPFIFIVISYAYITRSVLRVPSVGGRYKAFSTCGSHLTVVTLFYGTIISVYIRPSSTYSVTKDRVVTVIYTVVTPMLNPFIYSLRNKDMKQALKKLTRRT", "length": 332, "header": "tr|A0A9J7GAX6-1|A0A9J7GAX6_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100772267 PE=3 SV=1 CANONICAL=A0A9J7GAX6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GAX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAX6/entry#A0A9J7GAX6-1", "sequence": { "sequence": "MTVWHQYKKPPYTTLEQEYLLRAAILRENQSHMTEFLLLGLTSDPKQQVWLFAGFLAMYLANVIGNSVIIAAIRGDTHLHTPMYFFLSNLSLVDICFTTVIVPQMLVNLLTQRKTILFTQCLAQMYFFVAFGITDSFLLAAMAIDRYVAICNPLHYTTTMSPRRCRLLVMVSWAVSHLHSLTHTILMGRLSFCGANVIHHFFCDVQPLLTLSCSDTSINELLAFTEGSIVIMSPFIFIVISYAYITRSVLRVPSVGGRYKAFSTCGSHLTVVTLFYGTIISVYIRPSSTYSVTKDRVVTVIYTVVTPMLNPFIYSLRNKDMKQALKKLTRRT", "length": 332, "header": "tr|A0A9J7GAX6-1|A0A9J7GAX6_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100772267 PE=3 SV=1 CANONICAL=A0A9J7GAX6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279440" } ] }, { "annotation": "Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7#function" }, { "database": "UniProtKB", "id": "PIRNR013022", "url": "https://www.uniprot.org/uniprotkb/PIRNR013022#function" }, { "database": "UniProtKB", "id": "A0A9J7JWM1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWM1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7" } ], "common_name": "Chinese hamster", 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"MVRGARQSQQPRSRLAPRLTGTVEKPPRKRKSRTEFTLKETMSSGGAEDDIPQGERKTVTDFCYLLDKSKQLFNGLRDLPQYGQKQWQSYFGRTFDVYTKLWKFQQQHRQVLDNRYGLKRWQIGEIASKIGQLYYHYYLRTSETSYLNEAFSFYSAIRQRSYYSQVNKEDRPELVVKKLRYYARFIVVCLLLNKMDVVKDLVKELSDEIEDYTHRFNTEDQVEWNLVLQEVAAFIEADPVMVLNDDNTIVITSNRLTETGAPLLEQGMIVGQLSLADALIIGNCNNQVKFSELTVDMFRMLQALEREPMNLASQMNKPGIQESADKPTRRENPHKYLLYKPTFSQLYTFLAASFKELPANSVLLIYLSATGVFPTGRSDGEGPYDFGGVLTNSNRDIINGDAIHKRNQSHKEMHCLHPGDLYPFTRKPLFIIVDSSNSVAYKNFTNLFGQPLVCLLSPTTYPKALQDQSQRGSLFTLFLNNPLMAFLFVSGLSSMRRGLWEKCQEYLRKINRDIAQLLTHSRSIDQAFLQFFGDEFLRLLLTRFVFCSATMRMHKAFRETRNYPESYPQLPRDETVENPHLQKHILELASILDVRNIFFENSMDDY", "length": 606, "header": "tr|A0A9J7GAY7-1|A0A9J7GAY7_CRIGR Isoform 1 of Protein SCAI OS=Cricetulus griseus OX=10029 GN=Scai PE=3 SV=1 CANONICAL=A0A9J7GAY7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GAY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7/entry#A0A9J7GAY3-1", "sequence": { "sequence": 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"MVRGARQSQQPRSRLAPRLTGTVEKPPRKRKSRTEFTLKETMSSGGAEDDIPQGERKTVTDFCYLLDKSKQLFNGLRDLPQYGQKQWQSYFGRTFDVYTKLWKFQQQHRQVLDNRYGLKRWQIGEIASKIGQLYYHYYLRTSETSYLNEAFSFYSAIRQRSYYSQVNKEDRPELVVKKLRYYARFIVVCLLLNKMDVVKDLVKELSDEIEDYTHRFNTEDQVEWNLVLQEVAAFIEADPVMVLNDDNTIVITSNRLTETGAPLLEQGMIVGQLSLADALIIGNCNNQVKFSELTVDMFRMLQALEREPMNLASQMNKPGIQESADKPTRRENPHKYLLYKPTFSQLYTFLAASFKELPANSVLLIYLSATGVFPTGRSDGEGPYDFGGVLTNSNRDIINGDAIHKRNQSHKEMHCLHPGDLYPFTRKPLFIIVDSSNSVAYKNFTNLFGQPLVCLLSPTTYPKALQDQSQRGSLFTLFLNNPLMAFLFVSGLSSMRRGLWEKCQEYLRKINRDIAQLLTHSRSIDQAFLQFFGDEFLRLLLTRFVFCSATMRMHKAFRETRNYPESYPQLPRDETVENPHLQKHILELASILDVRNIFFENSMDDY", "length": 606, "header": "tr|A0A9J7GAY7-1|A0A9J7GAY7_CRIGR Isoform 1 of Protein SCAI OS=Cricetulus griseus OX=10029 GN=Scai PE=3 SV=1 CANONICAL=A0A9J7GAY7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7/entry#A0A9J7GZT5-1", "sequence": { "sequence": "MDAPTLQRNFGDLPQYGQKQWQSYFGRTFDVYTKLWKFQQQHRQVLDNRYGLKRWQIGEIASKIGQLYYHYYLRTSETSYLNEAFSFYSAIRQRSYYSQVNKEDRPELVVKKLRYYARFIVVCLLLNKMDVVKDLVKELSDEIEDYTHRFNTEDQVEWNLVLQEVAAFIEADPVMVLNDDNTIVITSNRLTETGAPLLEQGMIVGQLSLADALIIGNCNNQVKFSELTVDMFRMLQALEREPMNLASQMNKPGIQESADKPTRRENPHKYLLYKPTFSQLYTFLAASFKELPANSVLLIYLSATGVFPTGRSDGEGPYDFGGVLTNSNRDIINGDAIHKRNQSHKEMHCLHPGDLYPFTRKPLFIIVDSSNSVAYKNFTNLFGQPLVCLLSPTTYPKALQDQSQRGSLFTLFLNNPLMAFLFVSGLSSMRRGLWEKCQEYLRKINRDIAQLLTHSRSIDQAFLQFFGDEFLRLLLTRFVFCSATMRMHKAFRETRNYPESYPQLPRDETVENPHLQKHILELASILDVRNIFFENSMDDY", "length": 540, "header": "tr|A0A9J7GZT5-1|A0A9J7GZT5_CRIGR Computationally mapped isoform of Protein SCAI isoform X5 OS=Cricetulus griseus OX=10029 GN=Scai PE=4 SV=1 CANONICAL=A0A9J7GAY7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7/entry#A0A9J7H1D0-1", "sequence": { "sequence": "MTEFTLKETMSSGGAEDDIPQGERKTVTDFCYLLDKSKQLFNGLRDLPQYGQKQWQSYFGRTFDVYTKLWKFQQQHRQVLDNRYGLKRWQIGEIASKIGQLYYHYYLRTSETSYLNEAFSFYSAIRQRSYYSQVNKEDRPELVVKKLRYYARFIVVCLLLNKMDVVKDLVKELSDEIEDYTHRFNTEDQVEWNLVLQEVAAFIEADPVMVLNDDNTIVITSNRLTETGAPLLEQGMIVGQLSLADALIIGNCNNQVKFSELTVDMFRMLQALEREPMNLASQMNKPGIQESADKPTRRENPHKYLLYKPTFSQLYTFLAASFKELPANSVLLIYLSATGVFPTGRSDGEGPYDFGGVLTNSNRDIINGDAIHKRNQSHKEMHCLHPGDLYPFTRKPLFIIVDSSNSVAYKNFTNLFGQPLVCLLSPTTYPKALQDQSQRGSLFTLFLNNPLMAFLFVSGLSSMRRGLWEKCQEYLRKINRDIAQLLTHSRSIDQAFLQFFGDEFLRLLLTRFVFCSATMRMHKAFRETRNYPESYPQLPRDETVENPHLQKHILELASILDVRNIFFENSMDDY", "length": 574, "header": "tr|A0A9J7H1D0-1|A0A9J7H1D0_CRIGR Computationally mapped isoform of Protein SCAI isoform X3 OS=Cricetulus griseus OX=10029 GN=Scai PE=4 SV=1 CANONICAL=A0A9J7GAY7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JWM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7/entry#A0A9J7JWM1-1", "sequence": { "sequence": "MVSLRPKETEICSRTEFTLKETMSSGGAEDDIPQGERKTVTDFCYLLDKSKQLFNGLRDLPQYGQKQWQSYFGRTFDVYTKLWKFQQQHRQVLDNRYGLKRWQIGEIASKIGQLYYHYYLRTSETSYLNEAFSFYSAIRQRSYYSQVNKEDRPELVVKKLRYYARFIVVCLLLNKMDVVKDLVKELSDEIEDYTHRFNTEDQVEWNLVLQEVAAFIEADPVMVLNDDNTIVITSNRLTETGAPLLEQGMIVGQLSLADALIIGNCNNQVKFSELTVDMFRMLQALEREPMNLASQMNKPGIQESADKPTRRENPHKYLLYKPTFSQLYTFLAASFKELPANSVLLIYLSATGVFPTGRSDGEGPYDFGGVLTNSNRDIINGDAIHKRNQSHKEMHCLHPGDLYPFTRKPLFIIVDSSNSVAYKNFTNLFGQPLVCLLSPTTYPKALQDQSQRGSLFTLFLNNPLMAFLFVSGLSSMRRGLWEKCQEYLRKINRDIAQLLTHSRSIDQAFLQFFGDEFLRLLLTRFVFCSATMRMHKAFRETRNYPESYPQLPRDETVENPHLQKHILELASILDVRNIFFENSMDDY", "length": 587, "header": "tr|A0A9J7JWM1-1|A0A9J7JWM1_CRIGR Computationally mapped isoform of Protein SCAI OS=Cricetulus griseus OX=10029 GN=Scai PE=3 SV=1 CANONICAL=A0A9J7GAY7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751763", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751763", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7" } ], "pmid": "" }, { "name": "negative regulation of Rho protein signal transduction", "id": "GO:0035024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035024", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 407, "end_pos": 409 }, { "start_pos": 443, "end_pos": 445 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GAZ5-1", "uniprot_ac": "A0A9J7GAZ5", "uniprot_id": "A0A9J7GAZ5_CRIGR", "mass": { "chemical_mass": 54409.0, "monoisotopic_mass": 54409.0 }, "refseq": { "ac": "XP_027280809", "name": "LOW QUALITY PROTEIN: SPRY domain-containing SOCS box protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280809" }, "gene_names": [ { "name": "Spsb3", "type": "recommended", "evidence": [ { "id": "A0A9J7GAZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAZ5" } ] }, { "name": "Spsb3", "type": "synonym", "evidence": [ { "id": "XP_027280809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280809" } ] } ], "protein_names": [ { "name": "SPRY domain-containing SOCS box protein 3", "type": "recommended", "evidence": [ { "id": "A0A9J7GAZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAZ5/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: SPRY domain-containing SOCS box protein 3", "type": "synonym", "evidence": [ { "id": "XP_027280809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280809" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280809", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280809" } ] }, { "annotation": "Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as CGAS and SNAI1. The ECS(SPSB3) complex catalyzes 'Lys-48'-linked ubiquitination of nuclear CGAS in cycling cells, leading to its degradation. Recognizes and binds nucleosome-bound CGAS: ubiquitination and degradation of nuclear CGAS during G1 and G2 phases is required to promote low intranuclear CGAS abundance before the next mitotic cycle. The ECS(SPSB3) complex also mediates ubiquitination and degradation of phosphorylated SNAI1.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAZ5#function" }, { "database": "UniProtKB", "id": "ARBA00056941", "url": "https://www.uniprot.org/uniprotkb/ARBA00056941#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GAZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAZ5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Spsb3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAZ5", "locus": {} } ], "crossref": [ { "id": "cd12876", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12876", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752604", "url": "https://www.ncbi.nlm.nih.gov/gene/100752604", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", 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"MHFSARKAHCSSCPYSTRILQMRRNAICWAQALRLLVQGKSMSLWNLGPCQWSHSKCIKILPFPIMKLQVLVMLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKMEALTSKSSADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDSAAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATITKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEEREKSLFNQTEAGLATQENVYERPVDYLPERDVYESLCRGEGVKLTPQRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD", "length": 620, "header": "tr|A0A9J7GEC4-1|A0A9J7GEC4_CRIGR Isoform 1 of procollagen-proline 4-dioxygenase OS=Cricetulus griseus OX=10029 GN=P4ha2 PE=3 SV=1 CANONICAL=A0A9J7GEC4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M028-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4/entry#A0A8C2M028-1", "sequence": { "sequence": "MKLQVLVMLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKMEALTSKSSADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDSAAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATITKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEEREKSLFNQTEAGLATQENVYERPVDYLPERDVYESLCRGEGVKLTPQRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD", "length": 535, "header": "tr|A0A8C2M028-1|A0A9J7GEC4_CRIGR Computationally mapped isoform of procollagen-proline 4-dioxygenase OS=Cricetulus griseus OX=10029 GN=P4ha2 PE=3 SV=1 CANONICAL=A0A9J7GEC4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4/entry#A0A9J7GEC2-1", "sequence": { "sequence": "MQFAGPRPSGYWFRILPFPIMKLQVLVMLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKMEALTSKSSADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDSAAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATITKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEEREKSLFNQTEAGLATQENVYERPVDYLPERDVYESLCRGEGVKLTPQRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD", "length": 555, "header": "tr|A0A9J7GEC2-1|A0A9J7GEC2_CRIGR Computationally mapped isoform of procollagen-proline 4-dioxygenase OS=Cricetulus griseus OX=10029 GN=P4ha2 PE=3 SV=1 CANONICAL=A0A9J7GEC4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4/entry#A0A9J7GEC4-1", "sequence": { "sequence": "MHFSARKAHCSSCPYSTRILQMRRNAICWAQALRLLVQGKSMSLWNLGPCQWSHSKCIKILPFPIMKLQVLVMLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKMEALTSKSSADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDSAAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATITKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEEREKSLFNQTEAGLATQENVYERPVDYLPERDVYESLCRGEGVKLTPQRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD", "length": 620, "header": "tr|A0A9J7GEC4-1|A0A9J7GEC4_CRIGR Isoform 1 of procollagen-proline 4-dioxygenase OS=Cricetulus griseus OX=10029 GN=P4ha2 PE=3 SV=1 CANONICAL=A0A9J7GEC4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4/entry#A0A9J7GEC8-1", "sequence": { "sequence": "MHFSARKAHCSSCPYSTRILQMRRNAICWAQALRLLVQGKSMSLWNLGPCQWSHSKCIKILPFPIMKLQVLVMLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKMEALTSKSSADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDSAAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATITKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEEREKSLFNQTEAGLATQENVYERPVDYLPERDVYESLCRGEGVKLTPQRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRSDEQDAFKRLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD", "length": 600, "header": "tr|A0A9J7GEC8-1|A0A9J7GEC8_CRIGR Computationally mapped isoform of procollagen-proline 4-dioxygenase OS=Cricetulus griseus OX=10029 GN=P4ha2 PE=3 SV=1 CANONICAL=A0A9J7GEC4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4/entry#A0A9J7JVY3-1", "sequence": { "sequence": "MHFSARKAHCSSCPYSTRILQMRRNAICWAQALRLLVQGKSMSLWNLGPCQWSHSKCIKILPFPIMKLQVLVMLMSWFGVLSWVQAEFFTSIGHMTDLIYAEKDLVQSLKEYILAEEAKLSKIKSWASKMEALTSKSSADPEGYLAHPVNAYKLVKRLNTDWPALGDLVLQDSAAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATITKSLVLDYLSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEEREKSLFNQTEAGLATQENVYERPVDYLPERDVYESLCRGEGVKLTPQRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGTTEVD", "length": 598, "header": "tr|A0A9J7JVY3-1|A0A9J7JVY3_CRIGR Computationally mapped isoform of procollagen-proline 4-dioxygenase OS=Cricetulus griseus OX=10029 GN=P4ha2 PE=3 SV=1 CANONICAL=A0A9J7GEC4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M028", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M028" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M028", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M028" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760683", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760683", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEC4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4" } ], "pmid": "" }, { "name": "L-ascorbic acid binding", "id": "GO:0031418", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031418", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEC4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4" } ], "pmid": "" }, { "name": "procollagen-proline 4-dioxygenase activity", "id": "GO:0004656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004656", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEC4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEC4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4" } ], "pmid": "" }, { "name": "procollagen-proline 4-dioxygenase complex", "id": "GO:0016222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016222", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEC4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GEC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC4" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe2OG dioxygenase", "eco_id": "ECO_0000259", "start_pos": 477, "end_pos": 605, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.14.11.2", "ec_name": "L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2.", "evidence": [ { "id": "1.14.11.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.14.11.2" }, { "id": "1.14.11.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.14.11.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 180, "end_pos": 182 }, { "start_pos": 329, "end_pos": 331 }, { "start_pos": 519, "end_pos": 521 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JJG0-1", "uniprot_ac": "A0A9J7JJG0", "uniprot_id": "A0A9J7JJG0_CRIGR", "mass": { "chemical_mass": 59144.0, "monoisotopic_mass": 59144.0 }, "refseq": { "ac": "XP_027263471", "name": "probable asparagine--tRNA ligase, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263471" }, "gene_names": [ { "name": "Nars2", "type": "recommended", "evidence": [ { "id": "A0A9J7JJG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" } ] }, { "name": "Nars2", "type": "synonym", "evidence": [ { "id": "XP_027263471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263471" } ] } ], "protein_names": [ { "name": "asparagine--tRNA ligase", "type": "recommended", "evidence": [ { "id": "A0A9J7JJG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.22", "type": "synonym", "evidence": [ { "id": "A0A9J7JJG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0/entry#names_and_taxonomy" } ] }, { "name": "probable asparagine--tRNA ligase, mitochondrial isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027263471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263471" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263471" } ] }, { "annotation": "Mitochondrial aminoacyl-tRNA synthetase that catalyzes the specific attachment of the asparagine amino acid (aa) to the homologous transfer RNA (tRNA), further participating in protein synthesis. The reaction occurs in a two steps: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn).", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M5T5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5T5#function" }, { "database": "UniProtKB", "id": "ARBA00058292", "url": "https://www.uniprot.org/uniprotkb/ARBA00058292#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJG0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nars2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0", "locus": {} } ], "crossref": [ { "id": "A0A9J7JJG0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JJG0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00776", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00776", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04318", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04318", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771333", "url": "https://www.ncbi.nlm.nih.gov/gene/100771333", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004522", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004522", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771333", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771333", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JJG0", "url": "https://www.orthodb.org/?gene=A0A9J7JJG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22594", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22594", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22594:SF34", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22594:SF34", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00152", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00152", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027263471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263471", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11180", "url": "https://www.rhea-db.org/rhea/11180", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M5T5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M5T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5T5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJG0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGAWRLLGALRLCSSVSCPRPRASAKLRVRDALGVQDASGECVTVQGWVRSVRSQKEVLFLHVNDGSSLESLQVVADSSFDSRELSFGSSVQVQGQLVKSLSKRQNVELKAEKIEVIGNCEAKAFPIKYKERHPLEYLRQYPHMRCRTNTLGSILRVRSEATAAIHSYFKDNGFVHIHTPVITSNDCEGAGELFQVEPSSKIKVPEENFFNVPAFLTVSGQLHLEVMSGAFTQVFTFGPTFRAENSQSRRHLAEFYMVEAEISFVESLQDLMQVMEELFKATTEMVLSNCPEDVELCHKFIAPGQKDRLEHMLKNNFLIISYTEAVEILKQAPQNFTFTPKWGVDLQTEHEKYLVKHCGNIPVFVINYPLALKPFYMRDNEDAPQHTVAAVDLLVPGVGELFGGSLREERYHILEHRLARIKVVSKCALSVGAPRDLDQAETDSKLMSDQPLQVLFSFYRIIAYASYFRVPHCLLVISTALLLIESLLSNRKHHLLISMVNDWRTLASLCVLPYKGPCVHNLE", "length": 524, "header": "tr|A0A9J7JJG0-1|A0A9J7JJG0_CRIGR Isoform 1 of asparagine--tRNA ligase OS=Cricetulus griseus OX=10029 GN=Nars2 PE=3 SV=1 CANONICAL=A0A9J7JJG0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M5T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0/entry#A0A8C2M5T5-1", "sequence": { "sequence": "MLGAWRLLGALRLCSSVSCPRPRASAKLRVRDALGVQDASGECVTVQGWVRSVRSQKEVLFLHVNDGSSLESLQVVADSSFDSRELSFGSSVQVQGQLVKSLSKRQNVELKAEKIEVIGNCEAKAFPIKYKERHPLEYLRQYPHMRCRTNTLGSILRVRSEATAAIHSYFKDNGFVHIHTPVITSNDCEGAGELFQVEPSSKIKVPEENFFNVPAFLTVSGQLHLEVMSGAFTQVFTFGPTFRAENSQSRRHLAEFYMVEAEISFVESLQDLMQVMEELFKATTEMVLSNCPEDVELCHKFIAPGQKDRLEHMLKNNFLIISYTEAVEILKQAPQNFTFTPKWGVDLQTEHEKYLVKHCGNIPVFVINYPLALKPFYMRDNEDAPQHTVAAVDLLVPGVGELFGGSLREERYHILEHRLARSGLRKAYQWYLDLRQFGSVPHGGFGMGFERYLQCILGVDNIKDVIPFPRFTHSCLL", "length": 477, "header": "tr|A0A8C2M5T5-1|A0A9J7JJG0_CRIGR Computationally mapped isoform of asparagine--tRNA ligase OS=Cricetulus griseus OX=10029 GN=Nars2 PE=3 SV=1 CANONICAL=A0A9J7JJG0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0/entry#A0A9J7JJG0-1", "sequence": { "sequence": "MLGAWRLLGALRLCSSVSCPRPRASAKLRVRDALGVQDASGECVTVQGWVRSVRSQKEVLFLHVNDGSSLESLQVVADSSFDSRELSFGSSVQVQGQLVKSLSKRQNVELKAEKIEVIGNCEAKAFPIKYKERHPLEYLRQYPHMRCRTNTLGSILRVRSEATAAIHSYFKDNGFVHIHTPVITSNDCEGAGELFQVEPSSKIKVPEENFFNVPAFLTVSGQLHLEVMSGAFTQVFTFGPTFRAENSQSRRHLAEFYMVEAEISFVESLQDLMQVMEELFKATTEMVLSNCPEDVELCHKFIAPGQKDRLEHMLKNNFLIISYTEAVEILKQAPQNFTFTPKWGVDLQTEHEKYLVKHCGNIPVFVINYPLALKPFYMRDNEDAPQHTVAAVDLLVPGVGELFGGSLREERYHILEHRLARIKVVSKCALSVGAPRDLDQAETDSKLMSDQPLQVLFSFYRIIAYASYFRVPHCLLVISTALLLIESLLSNRKHHLLISMVNDWRTLASLCVLPYKGPCVHNLE", "length": 524, "header": "tr|A0A9J7JJG0-1|A0A9J7JJG0_CRIGR Isoform 1 of asparagine--tRNA ligase OS=Cricetulus griseus OX=10029 GN=Nars2 PE=3 SV=1 CANONICAL=A0A9J7JJG0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M5T5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5T5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M5T5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5T5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771333", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771333", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJG0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJG0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" } ], "pmid": "" }, { "name": "asparagine-tRNA ligase activity", "id": "GO:0004816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004816", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJG0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJG0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJG0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "asparaginyl-tRNA aminoacylation", "id": "GO:0006421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006421", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJG0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11180", "name": "", "equation": "tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7JJG0-1", "A0A8C2NAQ1-1" ], "evidence": [ { "id": "11180", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11180" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2NAQ1", "gene_name": "Nars1", "activity": [ { "ec_number": "6.1.1.22", "activity": "tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+).", "evidence": [ { "id": "A0A8C2NAQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NAQ1" } ] }, { "ec_number": "6.1.1.22", "activity": "", "evidence": [ { "id": "A0A8C2NAQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NAQ1" } ] } ] }, { "uniprot_ac": "A0A9J7JJG0", "gene_name": "Nars2", "activity": [ { "ec_number": "6.1.1.22", "activity": "tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+).", "evidence": [ { "id": "A0A9J7JJG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" } ] }, { "ec_number": "6.1.1.22", "activity": "", "evidence": [ { "id": "A0A9J7JJG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JJG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJG0" }, { "id": "PS50862", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50862" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminoacyl-transfer RNA synthetases class-II family profile", "eco_id": "ECO_0000259", "start_pos": 156, "end_pos": 436, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.1.1.22", "ec_name": "tRNA(Asn) + L-asparagine + ATP = L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+).", "evidence": [ { "id": "6.1.1.22", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.22" }, { "id": "6.1.1.22", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.1.1.22" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 336, "end_pos": 338 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDM3-1", "uniprot_ac": "A0A9J7GDM3", "uniprot_id": "A0A9J7GDM3_CRIGR", "mass": { "chemical_mass": 87929.0, "monoisotopic_mass": 87929.0 }, "refseq": { "ac": "XP_027282785", "name": "arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282785" }, "gene_names": [ { "name": "Acap1", "type": "recommended", "evidence": [ { "id": "A0A9J7GDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3" } ] }, { "name": "Acap1", "type": "synonym", "evidence": [ { "id": "XP_027282785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282785" } ] } ], "protein_names": [ { "name": "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A9J7GDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3/entry#names_and_taxonomy" } ] }, { "name": "Centaurin-beta", "type": "synonym", "evidence": [ { "id": "A0A9J7GDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3/entry#names_and_taxonomy" } ] }, { "name": "Cnt-b", "type": "synonym", "evidence": [ { "id": "A0A9J7GDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3/entry#names_and_taxonomy" } ] }, { "name": "arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027282785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282785" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282785" } ] }, { "annotation": "GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSU1#function" }, { "database": "UniProtKB", "id": "ARBA00056671", "url": "https://www.uniprot.org/uniprotkb/ARBA00056671#function" } ] }, { "annotation": "GTPase-activating protein for the ADP ribosylation factor family.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSU1#function" }, { "database": "UniProtKB", "id": "RU369028", "url": "https://www.uniprot.org/uniprotkb/RU369028#function" }, { "database": "UniProtKB", "id": "A0A9J7GDM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3#function" }, { "database": "UniProtKB", "id": "A0A9J7JYW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW6#function" }, { "database": "UniProtKB", "id": "A0A9J7H416", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H416#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Acap1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3", "locus": {} } ], "crossref": [ { "id": "A0A9J7GDM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GDM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07639", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07639", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08852", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08852", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765780", "url": "https://www.ncbi.nlm.nih.gov/gene/100765780", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765780", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765780", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDM3", "url": "https://www.orthodb.org/?gene=A0A9J7GDM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23180", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23180", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23180:SF197", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23180:SF197", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282785", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MSU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H416", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H416", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H416-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H416-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYW6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYW6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVKLDFEECLKDSPRFRASIELVETEVSELETRLEKLLKLGSCLLESGHHYLSASRAFVVGICDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGFREARRDFWRGAENLEAALTHNAEVPRRRVQEAEEAGTALRTARAGYLSRALDYALQVNVIEDKRKFDIMEFVLRLVEAQATYFQQGHEELNRLAQYRKELGAQLHDLVLNSAREKRDMEQRHVLLKQKELGGEEPEPSLKEGPSGLVMEGHLFKRASNAFKTWSRRWFTIQNNQLVYQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCFLQADSERLLQLWINAVQSSIASAFSQAHLDNSSRGPGQVSGYLALGSAATLGSGGAARGREPGGVGQVAAQVQSVEGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVVINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGPPRGHPPVPPKPSIRPQLGIVRSKSESPSDDLGSLHPGALLFQAAGHPPSLPTMADALAHGADVNWVNVGRGNATPLIRATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLSARDTEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQAGKVNLDSGPHQILAPCLLVPLLSSCINAIVYSTNMFWAHKRAWPSEQRKGKARGCAYDAPTHQELAPSDPPYCPVMLFVVGQLSSLLSVLLRG", "length": 800, "header": "tr|A0A9J7GDM3-1|A0A9J7GDM3_CRIGR Isoform 1 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein OS=Cricetulus griseus OX=10029 GN=Acap1 PE=4 SV=1 CANONICAL=A0A9J7GDM3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MSU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3/entry#A0A8C2MSU1-1", "sequence": { "sequence": "MTVKLDFEECLKDSPRFRASIELVETEVSELETRLEKLLKLGSCLLESGHHYLSASRAFVVGICDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGFREARRDFWRGAENLEAALTHNAEVPRRRVQEAEEAGTALRTARAGYLSRALDYALQVNVIEDKRKFDIMEFVLRLVEAQATYFQQGHEELNRLAQYRKELGAQLHDLVLNSAREKRDMEQRHVLLKQKELGGEEPEPSLKEGPSGLVMEGHLFKRASNAFKTWSRRWFTIQNNQLVYQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCFLQADSERLLQLWINAVQSSIASAFSQAHLDNSSRGPGQVSGYLALGSAATLGSGGAARGREPGGVGQVAAQVQSVEGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVVINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGPPRGHPPVPPKPSIRPQLGIVRSKSESPSDDLGSLHPGALLFQAAGHPPSLPTMADALAHGADVNWVNVGRGNATPLIRATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLSARDTEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQAGDETYLDIFRDFSLMASDDPEKLSRRSHDLHTL", "length": 740, "header": "tr|A0A8C2MSU1-1|A0A9J7GDM3_CRIGR Computationally mapped isoform of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein OS=Cricetulus griseus OX=10029 GN=Acap1 PE=4 SV=1 CANONICAL=A0A9J7GDM3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3/entry#A0A9J7GDM3-1", "sequence": { "sequence": "MTVKLDFEECLKDSPRFRASIELVETEVSELETRLEKLLKLGSCLLESGHHYLSASRAFVVGICDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGFREARRDFWRGAENLEAALTHNAEVPRRRVQEAEEAGTALRTARAGYLSRALDYALQVNVIEDKRKFDIMEFVLRLVEAQATYFQQGHEELNRLAQYRKELGAQLHDLVLNSAREKRDMEQRHVLLKQKELGGEEPEPSLKEGPSGLVMEGHLFKRASNAFKTWSRRWFTIQNNQLVYQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCFLQADSERLLQLWINAVQSSIASAFSQAHLDNSSRGPGQVSGYLALGSAATLGSGGAARGREPGGVGQVAAQVQSVEGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVVINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGPPRGHPPVPPKPSIRPQLGIVRSKSESPSDDLGSLHPGALLFQAAGHPPSLPTMADALAHGADVNWVNVGRGNATPLIRATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLSARDTEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQAGKVNLDSGPHQILAPCLLVPLLSSCINAIVYSTNMFWAHKRAWPSEQRKGKARGCAYDAPTHQELAPSDPPYCPVMLFVVGQLSSLLSVLLRG", "length": 800, "header": "tr|A0A9J7GDM3-1|A0A9J7GDM3_CRIGR Isoform 1 of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein OS=Cricetulus griseus OX=10029 GN=Acap1 PE=4 SV=1 CANONICAL=A0A9J7GDM3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H416-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3/entry#A0A9J7H416-1", "sequence": { "sequence": "MEFVLRLVEAQATYFQQGHEELNRLAQYRKELGAQLHDLVLNSAREKRDMEQRHVLLKQKELGGEEPEPSLKEGPSGLVMEGHLFKRASNAFKTWSRRWFTIQNNQLVYQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCFLQADSERLLQLWINAVQSSIASAFSQAHLDNSSRGPGQVSGYLALGSAATLGSGGAARGREPGGVGQVAAQVQSVEGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVVINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGPPRGHPPVPPKPSIRPQLGIVRSKSESPSDDLGSLHPGALLFQAAGHPPSLPTMADALAHGADVNWVNVGRGNATPLIRATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLSARDTEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQAGKVNLDSGPHQILAPCLLVPLLSSCINAIVYSTNMFWAHKRAWPSEQRKGKARGCAYDAPTHQELAPSDPPYCPVMLFVVGQLSSLLSVLLRG", "length": 612, "header": "tr|A0A9J7H416-1|A0A9J7H416_CRIGR Computationally mapped isoform of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein OS=Cricetulus griseus OX=10029 GN=Acap1 PE=4 SV=1 CANONICAL=A0A9J7GDM3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3/entry#A0A9J7JYW6-1", "sequence": { "sequence": "MTVKLDFEECLKDSPRFRASIELVETEVSELETRLEKLLKLGSCLLESGHHYLSASRAFVVGICDLARLGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRGFREARRDFWRGAENLEAALTHNAEVPRRRVQEAEEAGTALRTARAGYLSRALDYALQVNVIEDKRKFDIMEFVLRLVEAQATYFQQGHEELNRLAQYRKELGAQLHDLVLNSAREKRDMEQRHVLLKQKELGGEEPEPSLKEGPSGLVMEGHLFKRASNAFKTWSRRWFTIQNNQLVYQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVSTSKSCFLQADSERLLQLWINAVQSSIASAFSQAHLDNSSRGPGQVSGYLALGSAATLGSGGAARGREPGGVGQVAAQVQSVEGNAQCCDCREPAPEWASINLGVTLCIQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVVINQIYEARVEAMAVKKPGPSCSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGPPRGHPPVPPKPSIRPQLGIVRSKSESPSDDLGSLHPGALLFQAAGHPPSLPTMADALAHGADVNWVNVGRGNATPLIRATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTG", "length": 654, "header": "tr|A0A9J7JYW6-1|A0A9J7JYW6_CRIGR Computationally mapped isoform of Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein OS=Cricetulus griseus OX=10029 GN=Acap1 PE=4 SV=1 CANONICAL=A0A9J7GDM3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSU1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSU1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSU1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765780", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765780", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 405, "end_pos": 527, "start_aa": "Gly", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7GDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDM3" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 265, "end_pos": 360, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 370, "end_pos": 372 }, { "start_pos": 607, "end_pos": 609 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDH2-1", "uniprot_ac": "A0A9J7GDH2", "uniprot_id": "A0A9J7GDH2_CRIGR", "mass": { "chemical_mass": 85894.0, "monoisotopic_mass": 85894.0 }, "refseq": { "ac": "XP_027281346", "name": "transmembrane channel-like protein 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281346" }, "gene_names": [ { "name": "Tmc8", "type": "recommended", "evidence": [ { "id": "A0A9J7GDH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ] }, { "name": "Tmc8", "type": "synonym", "evidence": [ { "id": "XP_027281346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281346" } ] } ], "protein_names": [ { "name": "Transmembrane channel-like protein", "type": "recommended", "evidence": [ { "id": "A0A9J7GDH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2/entry#names_and_taxonomy" } ] }, { "name": "transmembrane channel-like protein 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027281346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281346" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281346" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmc8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2", "locus": {} } ], "crossref": [ { "id": "100774079", "url": "https://www.ncbi.nlm.nih.gov/gene/100774079", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774079", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774079", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDH2", "url": "https://www.orthodb.org/?gene=A0A9J7GDH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281346", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MZG8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MZG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERSGDCVVPKLKGRGEAHHPGAPLVPAESKDRARPSRAPTGMSRQWSVQPGPGPRAAAEELWEEEVERLCASREPLRMLPYSMADKRFIRELREPEGARPSFWQRWHRREKVALQHLREAAQKLARGFGLWEGALYEIGGLFGTGIQSYFTFLRFLLLLNLLTLLMTASFVLLPLVWLHHPEPGPALKLSLQCSGSHLPQSGIPRFHNPLWNILTGRAFNNTYLFYGAYRAGPERRSAYSIRLAYLLSPMACLLLCFCGALRRMVEALPHQPLLGQGYRAPLSAKVFSSWDFCIRVWEAATIKKHEISNELKVELEEGRRLELAQQQTRAQKACHLLAYLRTNVLIVLLVAGAISAIFWATKYSQDNKEESLFLVLQYLPPGVIALVNFLGPQLFTVVIQLENYPPSTEVNLTLIWCVVLKLASLGMFSFSLGQTVLCVGRNRTSCESYGYNACEYQCWENSVGEELYKLIIFNSLLTVAFAFLVTLPRRLLVERFSGWFWTWLDREEFLVPKNVLDIVAAQTVTWMALFYCPLLPLLNSVFLFLTFYIKKYTLLRNSRASPRLFRASSSTFFFQLVLLLGLLLAAVPLGYVTSSTHSSWDCGLFANYSAPWQVVPELVALQLPPSGQRALRYLSSHAFSFPLLILLSLVLTVCVSQSRANARAIHGLRKQLVWQVQEKWHLVDDLSRLLPELSPEPESPRSRASRPRSFCPGFPCPGSPGPRTPRLGSSTRLSSSSPGTPGTPGASDPVSRFHFPSRTER", "length": 762, "header": "tr|A0A9J7GDH2-1|A0A9J7GDH2_CRIGR Isoform 1 of Transmembrane channel-like protein OS=Cricetulus griseus OX=10029 GN=Tmc8 PE=3 SV=1 CANONICAL=A0A9J7GDH2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MZG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2/entry#A0A8C2MZG8-1", "sequence": { "sequence": "MSRQWSVQPGPGPRAAAEELWEEEVERLCASREPLRMLPYSMADKRFIRELREPEGARPSFWQRWHRREKVALQHLREAAQKLARGFGLWEGALYEIGGLFGTGIQSYFTFLRFLLLLNLLTLLMTASFVLLPLVWLHHPEPGPALKLSLQCSGSHLPQSGIPRFHNPLWNILTGRAFNNTYLFYGAYRAGPERRSAYSIRLAYLLSPMACLLLCFCGALRRMVEALPHQPLLGQGYRAPLSAKVFSSWDFCIRVWEAATIKKHEISNELKVELEEGRRLELAQQQTRAQKACHLLAYLRTNVLIVLLVAGAISAIFWATKYSQDNKEESLFLVLQYLPPGVIALVNFLGPQLFTVVIQLENYPPSTEVNLTLIWCVVLKLASLGMFSFSLGQTVLCVGRNRTSCESYGYNACEYQCWENSVGEELYKLIIFNSLLTVAFAFLVTLPRRLLVERFSGWFWTWLDREEFLVPKNVLDIVAAQTVTWMALFYCPLLPLLNSVFLFLTFYIKKYTLLRNSRASPRLFRASSSTFFFQLVLLLGLLLAAVPLGYVTSSTHSSWDCGLFANYSAPWQVVPELVALQLPPSGQRALRYLSSHAFSFPLLILLSLVLTVCVSQSRANARAIHGLRKQLVWQVQEKWHLVDDLSRLLPELSPEPESPRSRASRPRSFCPGFPCPGSPGPRTPRLGSSTRLSSSSPGTPGTPGASDPVSRFHFPSRTER", "length": 720, "header": "tr|A0A8C2MZG8-1|A0A9J7GDH2_CRIGR Computationally mapped isoform of Transmembrane channel-like protein OS=Cricetulus griseus OX=10029 GN=Tmc8 PE=3 SV=1 CANONICAL=A0A9J7GDH2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2/entry#A0A9J7GDH2-1", "sequence": { "sequence": "MERSGDCVVPKLKGRGEAHHPGAPLVPAESKDRARPSRAPTGMSRQWSVQPGPGPRAAAEELWEEEVERLCASREPLRMLPYSMADKRFIRELREPEGARPSFWQRWHRREKVALQHLREAAQKLARGFGLWEGALYEIGGLFGTGIQSYFTFLRFLLLLNLLTLLMTASFVLLPLVWLHHPEPGPALKLSLQCSGSHLPQSGIPRFHNPLWNILTGRAFNNTYLFYGAYRAGPERRSAYSIRLAYLLSPMACLLLCFCGALRRMVEALPHQPLLGQGYRAPLSAKVFSSWDFCIRVWEAATIKKHEISNELKVELEEGRRLELAQQQTRAQKACHLLAYLRTNVLIVLLVAGAISAIFWATKYSQDNKEESLFLVLQYLPPGVIALVNFLGPQLFTVVIQLENYPPSTEVNLTLIWCVVLKLASLGMFSFSLGQTVLCVGRNRTSCESYGYNACEYQCWENSVGEELYKLIIFNSLLTVAFAFLVTLPRRLLVERFSGWFWTWLDREEFLVPKNVLDIVAAQTVTWMALFYCPLLPLLNSVFLFLTFYIKKYTLLRNSRASPRLFRASSSTFFFQLVLLLGLLLAAVPLGYVTSSTHSSWDCGLFANYSAPWQVVPELVALQLPPSGQRALRYLSSHAFSFPLLILLSLVLTVCVSQSRANARAIHGLRKQLVWQVQEKWHLVDDLSRLLPELSPEPESPRSRASRPRSFCPGFPCPGSPGPRTPRLGSSTRLSSSSPGTPGTPGASDPVSRFHFPSRTER", "length": 762, "header": "tr|A0A9J7GDH2-1|A0A9J7GDH2_CRIGR Isoform 1 of Transmembrane channel-like protein OS=Cricetulus griseus OX=10029 GN=Tmc8 PE=3 SV=1 CANONICAL=A0A9J7GDH2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2/entry#A0A9J7GDJ6-1", "sequence": { "sequence": "MERSGDCVVPKLKGRGEAHHPGAPLVPAESKDRARPSRAPTGMSRQWSVQPGPGPRAAAEELWEEEVERLCASREPLRMLPYSMADKRFIRELREPEGARPSFWQRWHRREKVALQHLREAAQKLARGFGLWEGALYEIGGLFGTGIQSYFTFLRFLLLLNLLTLLMTASFVLLPLVWLHHPEPGPALKLSLQCSGSHLPQSGIPRFHNPLWNILTGRAFNNTYLFYGAYRAGPERRSAYSIRLAYLLSPMACLLLCFCGALRRMVEALPHQPLLGQGYRAPLSAKVFSSWDFCIRVWEAATIKKHEISNELKVELEEGRRLELAQQQTRAQKACHLLAYLRTNVLIVLLVAGAISAIFWATKYSQDNKEESLFLVLQYLPPGVIALVNFLGPQLFTVVIQLENYPPSTEVNLTLIWCVVLKLASLGMFSFSLGQTVLCVGRNRTSCESYGYNACEYQCWENSVGEELYKLIIFNSLLTVAFAFLVTLPRRLLVERFSGWFWTWLDREEFLVPKNVLDIVAAQTVTWMALFYCPLLPLLNSVFLFLTFYIKKYTLLRNSRASPRLFRASSSTFFFQLVLLLGLLLAAVPLGYVTSSTHSSWDCGLFANYSAPWQVVPELVALQLPPSGQRALRYLSSHAFSFPLLILLSLVLTVCVSQSRANARAIHGLRKQLVWVQEKWHLVDDLSRLLPELSPEPESPRSRASRPRSFCPGFPCPGSPGPRTPRLGSSTRLSSSSPGTPGTPGASDPVSRFHFPSRTER", "length": 761, "header": "tr|A0A9J7GDJ6-1|A0A9J7GDJ6_CRIGR Computationally mapped isoform of Transmembrane channel-like protein OS=Cricetulus griseus OX=10029 GN=Tmc8 PE=3 SV=1 CANONICAL=A0A9J7GDH2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 741, "start_aa": "Thr", "end_pos": 741, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr741", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 744, "start_aa": "Thr", "end_pos": 744, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr744", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZG8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZG8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MZG8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZG8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774079", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774079", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 7, "go_terms": [ { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" }, { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" }, { "name": "negative regulation of protein-containing complex assembly", "id": "GO:0031333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031333", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" }, { "name": "regulation of tumor necrosis factor-mediated signaling pathway", "id": "GO:0010803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010803", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" }, { "name": "intracellular 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[ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" }, { "name": "protein sequestering activity", "id": "GO:0140311", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140311", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 443, "end_pos": 445, "annotation": "n_glycosylation_sequon" }, { "start_pos": 608, "end_pos": 610, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GDH2", "database": "UniProtKB", "url": 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:: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007639467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639467" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zmynd8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89", "locus": {} } ], "crossref": [ { "id": "A0A9J7GD89", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GD89", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05508", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05508", "database": "CDD", "categories": [ "Protein Classification" ] 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"https://www.uniprot.org/uniprotkb/A0A9J7JT45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUW0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHPQSLAEEEIKTEPEVVEGMDISTRSKDPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRLNGVMESFQLAAAPPIALAPRLPANNRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKIQRQQQQHQQQQQQQQQQQPHSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1269, "header": "tr|A0A9J7GD89-1|A0A9J7GD89_CRIGR Isoform 1 of Protein kinase C-binding protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N036-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A8C2N036-1", "sequence": { "sequence": "MSAGSLPLFSFGTEGLGSLSDQAASMADPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1192, "header": "tr|A0A8C2N036-1|A0A9J7GD89_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QNL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A8C2QNL7-1", "sequence": { "sequence": "MHPQSLAEEEIKTEPEVVEGMDISTRSKDPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1168, "header": "tr|A0A8C2QNL7-1|A0A9J7GD89_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7G7N1-1", "sequence": { "sequence": "MHPQSLAEEEIKTEPEVVEGMDISTRSKDPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1193, "header": "tr|A0A9J7G7N1-1|A0A9J7GD89_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G861-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7G861-1", "sequence": { "sequence": "MDISTRSKDPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKIQRQQQQHQQQQQQQQQQQPHSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1197, "header": "tr|A0A9J7G861-1|A0A9J7GD89_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7G8L3-1", "sequence": { "sequence": "MDISTRSKDPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRLNGVMESFQLAAAPPIALAPRLPANNRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1200, "header": "tr|A0A9J7G8L3-1|A0A9J7GD89_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G8V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7G8V4-1", "sequence": { "sequence": "MSAGSLPLFSFGTEGLGSLSDQAASMADPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRLNGVMESFQLAAAPPIALAPRLPANNRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKIQRQQQQHQQQQQQQQQQQPHSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1268, "header": "tr|A0A9J7G8V4-1|A0A9J7GD89_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GD89-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7GD89-1", "sequence": { "sequence": "MHPQSLAEEEIKTEPEVVEGMDISTRSKDPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRLNGVMESFQLAAAPPIALAPRLPANNRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKIQRQQQQHQQQQQQQQQQQPHSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1269, "header": "tr|A0A9J7GD89-1|A0A9J7GD89_CRIGR Isoform 1 of Protein kinase C-binding protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7GZN2-1", "sequence": { "sequence": "MTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRLNGVMESFQLAAAPPIALAPRLPANNRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKIQRQQQQHQQQQQQQQQQQPHSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1104, "header": "tr|A0A9J7GZN2-1|A0A9J7GZN2_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X12 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H0W6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7H0W6-1", "sequence": { "sequence": "MKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRLNGVMESFQLAAAPPIALAPRLPANNRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKIQRQQQQHQQQQQQQQQQQPHSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1181, "header": "tr|A0A9J7H0W6-1|A0A9J7H0W6_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X10 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7H4R3-1", "sequence": { "sequence": "MKLKYVQNVTLLLAKNETTGSVSPVAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKIQRQQQQHQQQQQQQQQQQPHSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 934, "header": "tr|A0A9J7H4R3-1|A0A9J7H4R3_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X13 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JML2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7JML2-1", "sequence": { "sequence": "MDISTRSKDPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRLNGVMESFQLAAAPPIALAPRLPANNRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKIQRQQQQHQQQQQQQQQQQPHSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1249, "header": "tr|A0A9J7JML2-1|A0A9J7JML2_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JT45-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7JT45-1", "sequence": { "sequence": "MDISTRSKDPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRLNGVMESFQLAAAPPIALAPRLPANNRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKIQRQQQQHQQQQQQQQQQQPHSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1224, "header": "tr|A0A9J7JT45-1|A0A9J7JT45_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JUW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD89/entry#A0A9J7JUW0-1", "sequence": { "sequence": "MHPQSLAEEEIKTEPEVVEGMDISTRSKDPGSTERTAQKRKFPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKILLSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESLDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEEPEDKEGSRVDKEAPGIKKKPKPANPVEVKEEVKSNSPASEKADPTPAKDKASPEPEKDSVEKAKPSPHPTKDKLKGKDDTDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKLPPSTAAGNQSPPETPVLTRSATQAPSAGVTVAATTSTMSTVTVTAPATAVTGSPVKKQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKIQRQQQQHQQQQQQQQQQQPHSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASAINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEASTDTGNKSSQGSSSNAQSAPSETASASKEKETPAEKSKDSSTLDLSGSRETPSSILLGSNQGSVSKRCDKQAAYAPTTTDHQPHPNYPSQKYHSRSSKTGLWSSSEEKRGSARSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1242, "header": "tr|A0A9J7JUW0-1|A0A9J7JUW0_CRIGR Computationally mapped isoform of Protein kinase C-binding protein 1 isoform X5 OS=Cricetulus griseus OX=10029 GN=Zmynd8 PE=4 SV=1 CANONICAL=A0A9J7GD89-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 708, "start_aa": "Thr", "end_pos": 708, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr708", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N036", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N036" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N036", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N036" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768704", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768704", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5XZV4-1", "protein_name": "Zinc finger, MYND-type containing 8", "gene_name": "Zmynd8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELRSRRSQGLKMSGSLAEEEIKTEQEVVEGMDISTRSKDPGSTERTAQKRKVPSPPHSSNGHSPQDSSTSPIKKKKKPGLLNSSSKDQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPVNNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIRKKFGVFNYSPFRTPYTPNSQYQMLLDPSNPSAGTAKTDKQEKVKLNFDMTASPKIILSKPLLSGGAGRRISLSDMPRSPTSTNSSVHTGSDVEQDPEKKAPSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQAPTPIMTKPDKTSTATTGSILNLNLDRSKAEMDLKELSESVQQQSAPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSESSDSEYVSDEEQKPKNEPEDPEDKEGSRVDKEAPAIKRKPKPSNQVEVKEEVKSNSPVGEKVDPAPAKDKASPEPEKDFAEKAKPSPHPTKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDPSGREGRKNKKEPKVPSPKQDAIGKPPPPTPAGNQSPPETPVLTRSATQAPAAGVTVAATTSTMSTVTVTAPATAAVTGSPVKKQRPLLPKETVPAVQRVVWNASSKFQTSSQKWHMQKIQRQQQQQQQQQQQQQSQQQQPQSSQGTRYQTRQAVKAVQQKEVTQSPSTSTITLVTSTQPAALVSSSGSASTLASVINADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELAEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEANQETGNKTSQGSSSNTQSAPSEPASTPKEKETSSSSSNSSSTEKSKDSNSTLDLSGSRETPSSILLGSNQGSVSKRYDKQPAYTPTTTDHQPHPNYPAQKYHSRSSKAGLWSSSEEKRGSSRSEHSAGTSTKNLMPKESRESRLDTFWD", "length": 1267 }, "evidence": [ { "id": "A0A9J7GD89", "url": "https://omabrowser.org/oma/group/A0A9J7GD89/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7KRS9-1", "protein_name": "MYND-type zinc finger-containing chromatin reader Zmynd8", "gene_name": "Zmynd8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MESTDSSDSSGDSLKSIPRPDFEALSAIGSPQPQLQSSSLDGHVEMEPVIMPSKRQKYIVSAPPGSANCSSNSSSSSPSNINVGSSLTMKLTKVQPQQHQAKSSTPNNKGKVAKEMVALQRSHIESEVLSNFVTGVSKLKSRKSRYVPGNLATQAVGGELSRSLNTSSENENKSLKVALKRSSSIPAPILDSDDDWQDEDIAWGVTTCRPRGRSMAFEDGERLANLNAEDRNIVPAYSMATRCRSRSKTLSLSNSWSNDDKGPRRSNLRSENEEFAKKHNAFLDRIIHDDRESELALNTSGEGESSLFSDASDTKTTTAKTPEEEAAERLALIYEEPPTPGWDPFCWKCRGCGKLMPCSKCLRSFHSYCVRPATTKFDSSWKCPECQVIEAAPKRLRRNGVSVDLLSQLLSFALDRMKHVRGAHKLRSPLEVFPLTYKKFFVNPVSFESLAQCIRNGAYQSTDEFLSEVKWIQHNALILDAGDAKVEQASKAVVKVCRQEANEIDTCPECYLNANSSDEWFVKVCRHPHLLLWAKLKGFPYWPAKAMGSSNSTLVNVRFFGKHDRAFVPVKDCFLYSAQNPNTQTSRRSARDLAECIREVEIHIDHIKRKIGAFNYAPYRTPYDPLEEQQQLEQMMPGVYAAIDRELEPANKTPLQFLIRKTADDKLSIVKKTKATESGNESDQSPSPTKKLSEVDVVSVTGSGCSDHSNVKSNNYEVISRSGESLTDSRCKVLLKRKSLAAKIVAESVETSEAVAPKRKHSLSDASFTSESSEHKRKSKHARKQHDNQDNQIEEAEKTGQEPPKSPTISKQNENLRDEENVIENAANDTSSASPVSASVVSVVELVRRRQGVTITKIPREQQQTAEDTAAVPIPLPTAPPPKQNIPKGNEAANPKQSDVERQQEQLIKKVIPFIEIKTEVMSEPDDEGIEEASPANQPQTDQVPLQQETITAQPESQMPAAAPAPQPKPVDNAPFEEVRIKEEILSEDEMETEQSIVSRRLKSVPPMPLPMPPPPPLPPREESPATADSVRFVGDTTIQRVSQKQGGKSTDTGGKRKGVQQVPIAGIPQAPSPTHSPLLSTAPSPSASPKPTSTLAVSKPPPPPPPKGKSASHLQFRGKNDRIPTSPPATAPPATNTSSLLRSNMVVIPVEQGGSCNAHSPMTIPVPPLRAVSKNTLQNTSTGSTSSCVPSSVSMPPPLAGLSIPPVATPTSQEESITNSGQPVGLLASALNGTANDVLSSDSIPNDPITPGLATALSEMLLHTGVPKLIARPRGALRSDGSQIYPSQAGPVSQKLKENAHKITDYFISVIEDTLSDMATGDQSVLQARIAGLSLENERLKQHYDRQINDLHRTSELMISEMRKTLEQEHKRVISELRQQNAIELMRAVEEAKRKQWCANCMREAQLYCCWNTSYCDYPCQQLHWPGHSATCGQSVPPTIPVPPSVPTPIIEPGRAKAKVATPTATPSITNPSPSSQIMRTVAACPSAPPSANASSSKKWPPMMTLMNQSNQEAMLKLPATTYLRPVVSTTMTAPVTAPQPANNNSTNVIMAPTPPPGNNLATIISAQRNPPNYNAKHPNPAMPVQRFNIPLPITVNSNAPFMMAEQHQKQVPKATGRSGKNNSRMRQTYSNNINNSNPQGMRCNNNPQAIRQNQMNQQVFQP", "length": 1664 }, "evidence": [ { "id": "A0A9J7GD89", "url": "https://omabrowser.org/oma/group/A0A9J7GD89/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9ULU4-1", "protein_name": "MYND-type zinc finger-containing chromatin reader ZMYND8", "gene_name": "ZMYND8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613619.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007647441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647441" } ] }, { "annotation": "Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N058", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N058#function" }, { "database": "UniProtKB", "id": "ARBA00037148", "url": "https://www.uniprot.org/uniprotkb/ARBA00037148#function" }, { "database": "UniProtKB", "id": "A0A9J7GCU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "B9d1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100774531", "url": "https://www.ncbi.nlm.nih.gov/gene/100774531", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774531", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774531", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NMPIEVT", "url": "https://omabrowser.org/oma/group/NMPIEVT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2N058", "url": "https://www.orthodb.org/?gene=A0A8C2N058", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GCU9", "url": "https://www.orthodb.org/?gene=A0A9J7GCU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12968", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12968", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12968:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12968:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07162", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07162", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007647441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647441", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N058", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N058", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N058-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N058-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACHPFPRQPGSLLATARGLRRSPGPVVPWLLQVPASSCSWSTGRWRAPSFQSMMTSTASTALCMARTGPPRRVWRRGSHRSHPRAKMYGKHWCGTSPSMSPLKVPTPMAIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTIPMFVPESTSTLQKFTSWFMGRRPEYTDPKVVAQGEGREVTRVRSQGFVTLLFNVVTKDMKKLGYDTGPVDTQGVLGPSLPQVNPQ", "length": 230, "header": "tr|A0A9J7GCU9-1|A0A9J7GCU9_CRIGR Isoform 1 of B9 domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=B9d1 PE=3 SV=1 CANONICAL=A0A9J7GCU9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N058-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9/entry#A0A8C2N058-1", "sequence": { "sequence": "MAAASPSVFLLMVNGQVESAQFPEYDDLYCKYCFVYGQDWAPTAGLEEGISQIASKSQDVRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTIPMFVPESTSTLQKFTSWFMGRRPEYTDPKVVAQGEGREVTRVRSQGFVTLLFNVVTKDMKKLGYDTGPVDTQGVLGPSLPQVNPQ", "length": 204, "header": "tr|A0A8C2N058-1|A0A9J7GCU9_CRIGR Computationally mapped isoform of B9 domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=B9d1 PE=3 SV=1 CANONICAL=A0A9J7GCU9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9/entry#A0A9J7GCU9-1", "sequence": { "sequence": "MACHPFPRQPGSLLATARGLRRSPGPVVPWLLQVPASSCSWSTGRWRAPSFQSMMTSTASTALCMARTGPPRRVWRRGSHRSHPRAKMYGKHWCGTSPSMSPLKVPTPMAIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTIPMFVPESTSTLQKFTSWFMGRRPEYTDPKVVAQGEGREVTRVRSQGFVTLLFNVVTKDMKKLGYDTGPVDTQGVLGPSLPQVNPQ", "length": 230, "header": "tr|A0A9J7GCU9-1|A0A9J7GCU9_CRIGR Isoform 1 of B9 domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=B9d1 PE=3 SV=1 CANONICAL=A0A9J7GCU9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N058", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N058" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N058", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N058" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774531", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774531", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BIY2-1", "protein_name": "B9 domain-containing protein 1", "gene_name": "B9D1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAAGPSVFLVMVNGQVESAQFPEYDDLYCKYCFVYGQDWAPTAGLEEGISQITSKSRDARRALVWNFPIDVTFKSTNPHGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTVPMFVPESASRLQRFTSWFMGRRPEYTDPRVVAQGEGREVTRVRSQGFVTLLFNVVTKDMRKLGYDTGPPDTRGVLGPSPPQGLPR", "length": 204 }, "evidence": [ { "id": "A0A9J7GCU9", "url": "https://omabrowser.org/oma/group/A0A9J7GCU9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9R1S0-1", "protein_name": "B9 domain-containing protein 1", "gene_name": "B9d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAASPSVFLLMITGQVESAQFPEYDDLYCKYCFVYGQDWAPTAGLEEGISQIASKSQDVRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPLSPGRHKRTIPMFVPESTSTLQKFTSWFMGRRPEYTDPKVVAQGEGREVTRVRSQGFVTLLFNVVTKDMKKLGYDTGPVDTQGVLGPSLPQGNPQ", "length": 204 }, "evidence": [ { "id": "A0A9J7GCU9", "url": "https://omabrowser.org/oma/group/A0A9J7GCU9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPM9-1", "protein_name": "B9 domain-containing protein 1", "gene_name": "B9D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATASPSVFLLMVNGQVESAQFPEYDDLYCKYCFVYGQDWAPTAGLEEGISQITSKSQDVRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTIPMFVPESTSKLQKFTSWFMGRRPEYTDPKVVAQGEGREVTRVRSQGFVTLLFNVVTKDMRKLGYDTGPSDTQGVLGPSPPQSFPQ", "length": 204 }, "evidence": [ { "id": "A0A9J7GCU9", "url": "https://omabrowser.org/oma/group/A0A9J7GCU9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VF59-1", "protein_name": "B9 domain-containing protein 1", "gene_name": "B9d1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSASEGISLPGNEETTPPHEKHKQKAKKAKKKSRSAKESVPNAMDAKATASYFSLSIVGQIVSATFPLGPDKEFVFLRYEMVAGPDWQLSSGPQHGLTQLATNRRGHFNEPIVFNMPIEVTYKSTSPYGWPQILVTVFGRSGLGRETLLGYAHIHLPVFGSRRPADQTEQLQAPILMPKCPNMMADITSWLLRREPELKDPKVLLDNLKCKGLSMESYGSLQFQLSSVMRGARKLGYHWHS", "length": 241 }, "evidence": [ { "id": "A0A9J7GCU9", "url": "https://omabrowser.org/oma/group/A0A9J7GCU9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9" } ], "pmid": "" }, { "name": "MKS complex", "id": "GO:0036038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036038", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9" } ], "pmid": "" }, { "name": "smoothened signaling pathway", "id": "GO:0007224", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007224", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hedgehog receptor activity", "id": "GO:0008158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008158", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], 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"https://www.ncbi.nlm.nih.gov/protein/XP_016833015" }, "gene_names": [ { "name": "Mybbp1a", "type": "recommended", "evidence": [ { "id": "A0A9J7GDD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ] }, { "name": "Mybbp1a", "type": "synonym", "evidence": [ { "id": "XP_016833015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833015" } ] } ], "protein_names": [ { "name": "Myb-binding protein 1A isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7GDD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4/entry#names_and_taxonomy" } ] }, { "name": "myb-binding protein 1A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016833015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833015" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 331 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614234.1) and transcript sequence (JP042393.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016833015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833015" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mybbp1a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4", "locus": {} } ], "crossref": [ { "id": "100758378", "url": "https://www.ncbi.nlm.nih.gov/gene/100758378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758378", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N074", "url": "https://www.orthodb.org/?gene=A0A8C2N074", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GDD4", "url": "https://www.orthodb.org/?gene=A0A9J7GDD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13213:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13213:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26720", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26720", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016833015", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016833015", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N074", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N074", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N074-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N074-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEMKSPAKAESASPTETTQDERRGLLEHSREFLDFFWDIAKPEQETRLQATEKLLEYLRTRPSGSEMKYALKRLITGLGVGRETARPCYSLALAQLLQAFEDIPLCSILGQIQEKYNLQTVNKGMMRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLKILSHHYNHLQGQPIKVLVDILSQVPESMFQEILPKILKGGDLNVILSSPKYLELFLLAQQRVPAKLESLMGSVDLFSEENIPSLVNVLKTAANSVRKEHKLPEVALDLLRLALKENKFTLFWKEVLEQRLLNKPCWSASYMCFRLLGASLPLLSEEQLRLVMRGDLIRHFGEHMVISKPQNLFKIIPEISSYVSTFLEGCQDDPKRQFAMMVAFTSITNQGLPVMPTFWRVTRLLSSEALQSYVTWLRDMFLQPDLDSLVDFSTANQKRAQDASFNVPERSVFRLRKWIIHRLVSLVEHLHLEKDDAVVEQVARFCFFHAFFKTKKATPQIPETKQHFSFPLDDRNRSVIIGAFFSLLQTLSMKSRQTPDLNECAKPWTYRLVQLADMLLNHSRNVTVVTPFTTQQRQAWDQMMSTLKELEARSSETRALAFQHLLLLVGLHLFKSPTESCDVLGDIQTCIKKSMEQNPRRSRSRAKASQEPAWVEVMVEILLSLLAQPSNLMRKVVRNVFGHICSHLTPRGLQLILAVLNPETNEDEDDNVVVTDDTNEKQLKRGEDEDSDSEDNKNSDSDVDSEDGAESEEEDRDKDVDPGFRQQLMEVLQAGNALGGVDSEDEEELGDEAMMALDQNLASLFAEQKLRIQARQEEKNKLQKEKQLRRDFQIRVLDLIEVLVTKQPEHPLILELLEPLLSIIQRSMRSKGSTKQEQDLLHKTARIFMHHLCRARHYCHEVGPCAEGLHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNTAKRYEDGQNLPGAEPKDSELSHQAQTANCLDLDFVTRVYSAALESFLTKRNSPLTVPMFLSLFSRYPVICKNLLPVLVQHVSGPLRPRHQAQACLLLQKTLSARELRVCFEDPEWEQLIGQVLGKLTQTLQTLGDAQSKGEQQREFSTLELLNILFKTVNHEKLSVDLTSVLGLLQSKQQKLQQSLQQGNHSSGSNRLYDLYWQAMRMLGVQRPKSEKKNVKDVPSDSQSPISQKRKKKGFLPETKKRKKVKSEDTTPGKDATSGQEVVTAGATPAAAGEGQPPSTGKKKRKRVKANTPSQVNGTPVTKSPAPNNPTLSPSTPFKSPKLQKKKEKLSQVNGGTPVSPIEPEGKEHHQKALPTKEVLRKSPQSALPRKRARLSLVSRSPSLLQSVVKKRKVARRKMQTP", "length": 1347, "header": "tr|A0A9J7GDD4-1|A0A9J7GDD4_CRIGR Isoform 1 of Myb-binding protein 1A isoform X3 OS=Cricetulus griseus OX=10029 GN=Mybbp1a PE=3 SV=1 CANONICAL=A0A9J7GDD4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N074-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4/entry#A0A8C2N074-1", "sequence": { "sequence": "MAEMKSPAKAESASPTETTQDERRGLLEHSREFLDFFWDIAKPEQETRLQATEKLLEYLRTRPSGSEMKYALKRLITGLGVGRETARPCYSLALAQLLQAFEDIPLCSILGQIQEKYNLQTVNKGMMRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLKILSHHYNHLQGQPIKVLVDILSQVPESMFQEILPKILKGGDLNVILSSPKYLELFLLAQQRVPAKLESLMGSVDLFSEENIPSLVNVLKTAANSVRKEHKLPEVALDLLRLALKENKFTLFWKEVLEQRLLNKPCWSASYMCFRLLGASLPLLSEEQLRLVMRGDLIRHFGEHMVISKPQNLFKIIPEISSYVSTFLEGCQDDPKRQFAMMVAFTSITNQGLPVMPTFWRVTRLLSSEALQSYVTWLRDMFLQPDLDSLVDFSTANQKRAQDASFNVPERSVFRLRKWIIHRLVSLVEHLHLEKDDAVVEQVARFCFFHAFFKTKKATPQIPETKQHFSFPLDDRNRSVIIGAFFSLLQTLSMKSRQTPDLNECAKPWTYRLVQLADMLLNHSRNVTVVTPFTTQQRQAWDQMMSTLKELEARSSETRALAFQHLLLLVGLHLFKSPTESCDVLGDIQTCIKKSMEQNPRRSRSRAKASQEPAWVEVMVEILLSLLAQPSNLMRKVVRNVFGHICSHLTPRGLQLILAVLNPETNEDEDDNVVVTDDTNEKQLKRGEDEDSDSEDNKNSDSDVDSEDGAESEEEDRDKDVDPGFRQQLMEVLQAGNALGGVDSEDEEELGDEAMMALDQNLASLFAEQKLRIQARQEEKNKLQKEKQLRRDFQIRVLDLIEVLVTKQPEHPLILELLEPLLSIIQRSMRSKGSTKQEQDLLHKTARIFMHHLCRARHYCHEVGPCAEGLHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNTAKRYEDGQNLPGAEPKDSEAQTANCLDLDFVTRVYSAALESFLTKRNSPLTVPMFLSLFSRYPVICKNLLPVLVQHVSGPLRPRHQAQACLLLQKTLSARELRVCFEDPEWEQLIGQVLGKLTQTLQTLGDAQSKGEQQREFSTLELLNILFKTVNHEKLSVDLTSVLGLLQSKQQKLQQSLQQGNHSSGSNRLYDLYWQAMRMLGVQRPKSEKKNVKDVPSDSQSPISQKRKKKGFLPETKKRKKVKSEDTTPGKDATSGQEVVTAGATPAAAGEGQPPSTGKKKRKRVKANTPSQVNGTPVTKSPAPNNPTLSPSTPFKSPKLQKKKEKLSQVNGGTPVSPIEPEGKEHHQKALPTKEVLRKSPQSALPRKRARLSLVSRSPSLLQSVVKKRKVARRKMQTP", "length": 1343, "header": "tr|A0A8C2N074-1|A0A9J7GDD4_CRIGR Computationally mapped isoform of Myb-binding protein 1A isoform X3 OS=Cricetulus griseus OX=10029 GN=Mybbp1a PE=3 SV=1 CANONICAL=A0A9J7GDD4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4/entry#A0A9J7GDD4-1", "sequence": { "sequence": "MAEMKSPAKAESASPTETTQDERRGLLEHSREFLDFFWDIAKPEQETRLQATEKLLEYLRTRPSGSEMKYALKRLITGLGVGRETARPCYSLALAQLLQAFEDIPLCSILGQIQEKYNLQTVNKGMMRPALFANLFGVLALFQSGRLVKDQEALMKSVKLLKILSHHYNHLQGQPIKVLVDILSQVPESMFQEILPKILKGGDLNVILSSPKYLELFLLAQQRVPAKLESLMGSVDLFSEENIPSLVNVLKTAANSVRKEHKLPEVALDLLRLALKENKFTLFWKEVLEQRLLNKPCWSASYMCFRLLGASLPLLSEEQLRLVMRGDLIRHFGEHMVISKPQNLFKIIPEISSYVSTFLEGCQDDPKRQFAMMVAFTSITNQGLPVMPTFWRVTRLLSSEALQSYVTWLRDMFLQPDLDSLVDFSTANQKRAQDASFNVPERSVFRLRKWIIHRLVSLVEHLHLEKDDAVVEQVARFCFFHAFFKTKKATPQIPETKQHFSFPLDDRNRSVIIGAFFSLLQTLSMKSRQTPDLNECAKPWTYRLVQLADMLLNHSRNVTVVTPFTTQQRQAWDQMMSTLKELEARSSETRALAFQHLLLLVGLHLFKSPTESCDVLGDIQTCIKKSMEQNPRRSRSRAKASQEPAWVEVMVEILLSLLAQPSNLMRKVVRNVFGHICSHLTPRGLQLILAVLNPETNEDEDDNVVVTDDTNEKQLKRGEDEDSDSEDNKNSDSDVDSEDGAESEEEDRDKDVDPGFRQQLMEVLQAGNALGGVDSEDEEELGDEAMMALDQNLASLFAEQKLRIQARQEEKNKLQKEKQLRRDFQIRVLDLIEVLVTKQPEHPLILELLEPLLSIIQRSMRSKGSTKQEQDLLHKTARIFMHHLCRARHYCHEVGPCAEGLHAQVERLVQQAGSQADASVALYYFNASLYLLRVLKGNTAKRYEDGQNLPGAEPKDSELSHQAQTANCLDLDFVTRVYSAALESFLTKRNSPLTVPMFLSLFSRYPVICKNLLPVLVQHVSGPLRPRHQAQACLLLQKTLSARELRVCFEDPEWEQLIGQVLGKLTQTLQTLGDAQSKGEQQREFSTLELLNILFKTVNHEKLSVDLTSVLGLLQSKQQKLQQSLQQGNHSSGSNRLYDLYWQAMRMLGVQRPKSEKKNVKDVPSDSQSPISQKRKKKGFLPETKKRKKVKSEDTTPGKDATSGQEVVTAGATPAAAGEGQPPSTGKKKRKRVKANTPSQVNGTPVTKSPAPNNPTLSPSTPFKSPKLQKKKEKLSQVNGGTPVSPIEPEGKEHHQKALPTKEVLRKSPQSALPRKRARLSLVSRSPSLLQSVVKKRKVARRKMQTP", "length": 1347, "header": "tr|A0A9J7GDD4-1|A0A9J7GDD4_CRIGR Isoform 1 of Myb-binding protein 1A isoform X3 OS=Cricetulus griseus OX=10029 GN=Mybbp1a PE=3 SV=1 CANONICAL=A0A9J7GDD4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1213, "start_aa": "Thr", "end_pos": 1213, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1213", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N074", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N074" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N074", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N074" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758378", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" }, { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" }, { "name": "NLS-dependent protein nuclear import complex", "id": "GO:0042564", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042564", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cellular response to glucose starvation", "id": "GO:0042149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042149", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" }, { "name": "intrinsic apoptotic signaling pathway by p53 class mediator", "id": "GO:0072332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072332", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase III", "id": "GO:0045945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045945", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" }, { "name": "positive regulation of anoikis", "id": "GO:2000210", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000210", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1129, "end_pos": 1131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1242, "end_pos": 1244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 926, "end_pos": 928, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1213 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1129, "end_pos": 1131 }, { "start_pos": 1242, "end_pos": 1244 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 557, "end_pos": 559 }, { "start_pos": 926, "end_pos": 928 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GEH0-1", "uniprot_ac": "A0A9J7GEH0", "uniprot_id": "A0A9J7GEH0_CRIGR", "mass": { "chemical_mass": 32457.0, "monoisotopic_mass": 32457.0 }, "refseq": { "ac": "XP_016831856", "name": "phosphoethanolamine/phosphocholine phosphatase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831856" }, "gene_names": [ { "name": "Phospho1", "type": "recommended", "evidence": [ { "id": "A0A9J7GEH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ] }, { "name": "Phospho1", "type": "synonym", "evidence": [ { "id": "XP_016831856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831856" } ] } ], "protein_names": [ { "name": "Phosphoethanolamine/phosphocholine phosphatase", "type": "recommended", "evidence": [ { "id": "A0A9J7GEH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.75", "type": "synonym", "evidence": [ { "id": "A0A9J7GEH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0/entry#names_and_taxonomy" } ] }, { "name": "phosphoethanolamine/phosphocholine phosphatase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016831856", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831856" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614015.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016831856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831856" } ] }, { "annotation": "Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate for bone mineralization. Acts in a non-redundant manner with PHOSPHO1 in skeletal mineralization: while PHOSPHO1 mediates the initiation of hydroxyapatite crystallization in the matrix vesicles (MVs), ALPL/TNAP catalyzes the spread of hydroxyapatite crystallization in the extracellular matrix.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEW9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEW9#function" }, { "database": "UniProtKB", "id": "ARBA00056980", "url": "https://www.uniprot.org/uniprotkb/ARBA00056980#function" }, { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Phospho1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0", "locus": {} } ], "crossref": [ { "id": "A0A9J7GEH0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GEH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16418", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16418", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760987", "url": "https://www.ncbi.nlm.nih.gov/gene/100760987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760987", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760987", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FHSHECQ", "url": "https://omabrowser.org/oma/group/FHSHECQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2QEW9", "url": "https://www.orthodb.org/?gene=A0A8C2QEW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GEH0", "url": "https://www.orthodb.org/?gene=A0A9J7GEH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20889", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20889", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20889:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20889:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06888", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06888", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016831856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831856", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10492", "url": "https://www.rhea-db.org/rhea/10492", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "16089", "url": "https://www.rhea-db.org/rhea/16089", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QEW9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QEW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCQRSWLWPANQTLPGRLPPRRLSLVPSSCSSSPCSQDVRMAAPGAPRFLLTFDFDETIVDENSDDSIVRAAPGQQLPESLRATYREGYYNEYMQRVFKYLGEQGVRPRDLRAVYETIPLSPGMGDLLQFVAKQGCFEVILISDANTFGVESALRAAGHHGLFRRIFSNPAGPDARGLLTLRPFHTHSCSRCPANMCKHKVLSEYLRERARDGVHFERLFYVGDGANDFCPLGLLASGDVAFPRRGYPMHRLIQEAQKAEPSSFRAHVVPWETAAEVRQHLQQVLKMY", "length": 288, "header": "tr|A0A9J7GEH0-1|A0A9J7GEH0_CRIGR Isoform 1 of Phosphoethanolamine/phosphocholine phosphatase OS=Cricetulus griseus OX=10029 GN=Phospho1 PE=3 SV=1 CANONICAL=A0A9J7GEH0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QEW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0/entry#A0A8C2QEW9-1", "sequence": { "sequence": "MSGCFPAVGLRCLSRDVRMAAPGAPRFLLTFDFDETIVDENSDDSIVRAAPGQQLPESLRATYREGYYNEYMQRVFKYLGEQGVRPRDLRAVYETIPLSPGMGDLLQFVAKQGCFEVILISDANTFGVESALRAAGHHGLFRRIFSNPAGPDARGLLTLRPFHTHSCSRCPANMCKHKVLSEYLRERARDGVHFERLFYVGDGANDFCPLGLLASGDVAFPRRGYPMHRLIQEAQKAEPSSFRAHVVPWETAAEVRQHLQQVLKMY", "length": 266, "header": "tr|A0A8C2QEW9-1|A0A9J7GEH0_CRIGR Computationally mapped isoform of Phosphoethanolamine/phosphocholine phosphatase OS=Cricetulus griseus OX=10029 GN=Phospho1 PE=3 SV=1 CANONICAL=A0A9J7GEH0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0/entry#A0A9J7GEH0-1", "sequence": { "sequence": "MCQRSWLWPANQTLPGRLPPRRLSLVPSSCSSSPCSQDVRMAAPGAPRFLLTFDFDETIVDENSDDSIVRAAPGQQLPESLRATYREGYYNEYMQRVFKYLGEQGVRPRDLRAVYETIPLSPGMGDLLQFVAKQGCFEVILISDANTFGVESALRAAGHHGLFRRIFSNPAGPDARGLLTLRPFHTHSCSRCPANMCKHKVLSEYLRERARDGVHFERLFYVGDGANDFCPLGLLASGDVAFPRRGYPMHRLIQEAQKAEPSSFRAHVVPWETAAEVRQHLQQVLKMY", "length": 288, "header": "tr|A0A9J7GEH0-1|A0A9J7GEH0_CRIGR Isoform 1 of Phosphoethanolamine/phosphocholine phosphatase OS=Cricetulus griseus OX=10029 GN=Phospho1 PE=3 SV=1 CANONICAL=A0A9J7GEH0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEW9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEW9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QEW9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEW9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760987", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8R2H9-1", "protein_name": "Phosphoethanolamine/phosphocholine phosphatase", "gene_name": "Phospho1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGCFPAVGLRCLSRDGRMAAPGAPRFLLTFDFDETIVDENSDDSIVRAAPGQQLPESLRATYREGYYNEYMQRVFKYLGEQGVRPRDLRAVYETIPLSPGMGDLLQFIAKQGSCFEVILISDANTFGVESALRAAGHHSLFRRILSNPSGPDARGLLTLRPFHTHSCSRCPANMCKHKVLSEYLRERARDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRAHVVPWETAADVRQHLQQVLKMC", "length": 267 }, "evidence": [ { "id": "A0A9J7GEH0", "url": "https://omabrowser.org/oma/group/A0A9J7GEH0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TCT1-1", "protein_name": "Phosphoethanolamine/phosphocholine phosphatase", "gene_name": "PHOSPHO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVILISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKSC", "length": 267 }, "evidence": [ { "id": "A0A9J7GEH0", "url": "https://omabrowser.org/oma/group/A0A9J7GEH0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "pyrophosphatase activity", "id": "GO:0016462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016462", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ], "pmid": "" }, { "name": "phosphocholine phosphatase activity", "id": "GO:0052731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052731", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ], "pmid": "" }, { "name": "phosphoethanolamine phosphatase activity", "id": "GO:0052732", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052732", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ], "pmid": "" }, { "name": "phosphatase activity", "id": "GO:0016791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016791", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ], "pmid": "" }, { "name": "extracellular vesicle", "id": "GO:1903561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903561", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "bone mineralization involved in bone maturation", "id": "GO:0035630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035630", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ], "pmid": "" }, { "name": "regulation of bone mineralization", "id": "GO:0030500", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030500", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10492", "name": "", "equation": "phosphocholine + H2O = choline + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7GEH0-1" ], "evidence": [ { "id": "10492", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10492" } ] }, { "id": "16089", "name": "", "equation": "phosphoethanolamine + H2O = ethanolamine + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3HIL5-1", "A0A9J7GEH0-1" ], "evidence": [ { "id": "16089", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16089" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7GEH0", "gene_name": "Phospho1", "activity": [ { "ec_number": "3.1.3.75", "activity": "phosphocholine + H2O = choline + phosphate.", "evidence": [ { "id": "A0A9J7GEH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ] }, { "ec_number": "3.1.3.75", "activity": "", "evidence": [ { "id": "A0A9J7GEH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH0" } ] } ] }, { "uniprot_ac": "G3HIL5", "gene_name": "Alpl", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "G3HIL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HIL5" } ] }, { "ec_number": 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This record is derived from a genomic sequence (NW_003613711.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007634288", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007634288" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Marchf5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3", "locus": {} } ], "crossref": [ { "id": "A0A9J7JIK3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JIK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16701", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16701", "database": "CDD", "categories": [ "Protein Classification" ] 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[ "Protein" ] }, { "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVHHSTLFSDNTFDVKVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA", "length": 293, "header": "tr|A0A9J7JIK3-1|A0A9J7JIK3_CRIGR Isoform 1 of E3 ubiquitin-protein ligase MARCHF5 OS=Cricetulus griseus OX=10029 GN=Marchf5 PE=4 SV=1 CANONICAL=A0A9J7JIK3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QKU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3/entry#A0A8C2QKU4-1", "sequence": { "sequence": "MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA", "length": 278, "header": "tr|A0A8C2QKU4-1|A0A9J7JIK3_CRIGR Computationally mapped isoform of E3 ubiquitin-protein ligase MARCHF5 OS=Cricetulus griseus OX=10029 GN=Marchf5 PE=4 SV=1 CANONICAL=A0A9J7JIK3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GU31-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3/entry#A0A9J7GU31-1", "sequence": { "sequence": "MERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA", "length": 145, "header": "tr|A0A9J7GU31-1|A0A9J7GU31_CRIGR Computationally mapped isoform of E3 ubiquitin-protein ligase MARCHF5 isoform X1 OS=Cricetulus griseus OX=10029 GN=Marchf5 PE=4 SV=1 CANONICAL=A0A9J7JIK3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3/entry#A0A9J7JIK3-1", "sequence": { "sequence": "MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVHHSTLFSDNTFDVKVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA", "length": 293, "header": "tr|A0A9J7JIK3-1|A0A9J7JIK3_CRIGR Isoform 1 of E3 ubiquitin-protein ligase MARCHF5 OS=Cricetulus griseus OX=10029 GN=Marchf5 PE=4 SV=1 CANONICAL=A0A9J7JIK3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QKU4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKU4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QKU4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QKU4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766578", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766578", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7FGS9-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF5", "gene_name": "Marchf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA", "length": 278 }, "evidence": [ { "id": "A0A9J7JIK3", "url": "https://omabrowser.org/oma/group/A0A9J7JIK3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3KNM2-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF5", "gene_name": "Marchf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA", "length": 278 }, "evidence": [ { "id": "A0A9J7JIK3", "url": "https://omabrowser.org/oma/group/A0A9J7JIK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZC24-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF5", "gene_name": "MARCHF5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA", "length": 278 }, "evidence": [ { "id": "A0A9J7JIK3", "url": "https://omabrowser.org/oma/group/A0A9J7JIK3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5ZJ41-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF5", "gene_name": "MARCHF5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSEQTGLALPQTMDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQTCLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEGA", "length": 281 }, "evidence": [ { "id": "A0A9J7JIK3", "url": "https://omabrowser.org/oma/group/A0A9J7JIK3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9NX47-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF5", "gene_name": "MARCHF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVACPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHKEGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPRIPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYFKQQQYLRQAHRKILNYPEQEEA", "length": 278 }, "evidence": [ { "id": "A0A9J7JIK3", "url": "https://omabrowser.org/oma/group/A0A9J7JIK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VN18-1", "protein_name": "E3 ubiquitin-protein ligase MARCHF5", "gene_name": "March5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADKAAAPSVDCAAPSVDCATPAIPAVEDHTTLTVPPASANKATDASTSTAVQVAVDGGEPERCCWICFATDEDNRLAAWVKPCQCRGTTKWVHQSCLYRWIDEKTQKGNALRTVSCPQCQTEYIIVFPQMGKLGGALEAIDNLIKRLSPFLAAGFFVGSLYWTAVTYGAVTFLQIVGHEHGMSIMESGDPLVLLIGLPAIPVGLVLGRLIRWEDALLRLIRNRGTVVRKFPFVSLIYPNLSQEEEQQSISNPATPALSDPVSATRVFCGALLLPTISSIVGRILFDTVDNTLHRTLLGGLTFITVKGILKIYLKQKQYGRRKKRRIVDYTEENIRNFMHRNNNSAAAARQERLPEQRPVPPAERRDAVITRQRGDSGGSVV", "length": 382 }, "evidence": [ { "id": "A0A9J7JIK3", "url": "https://omabrowser.org/oma/group/A0A9J7JIK3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "protein localization to mitochondrion", "id": "GO:0070585", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070585", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "protein autoubiquitination", "id": "GO:0051865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051865", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "protein K63-linked ubiquitination", "id": "GO:0070534", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070534", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "protein K27-linked ubiquitination", "id": "GO:0044314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044314", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "positive regulation of NLRP3 inflammasome complex assembly", "id": "GO:1900227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900227", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fission", "id": "GO:0090141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090141", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "negative regulation of cytoplasmic pattern recognition receptor signaling pathway", "id": "GO:0039532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039532", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "positive regulation of cGAS/STING signaling pathway", "id": "GO:0141111", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141111", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "GTPase binding", "id": "GO:0051020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JIK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIK3" }, { "id": "PS51292", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51292" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-CH-type", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 75, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JH52-1", "uniprot_ac": "A0A9J7JH52", "uniprot_id": "A0A9J7JH52_CRIGR", "mass": { "chemical_mass": 84783.0, "monoisotopic_mass": 84783.0 }, "refseq": { "ac": "XP_027269841", "name": "intraflagellar transport protein 81 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269841" }, "gene_names": [ { "name": "Ift81", "type": "recommended", "evidence": [ { "id": "A0A9J7JH52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52" } ] }, { "name": "Ift81", "type": "synonym", "evidence": [ { "id": "XP_027269841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269841" } ] } ], "protein_names": [ { "name": "Intraflagellar transport protein 81 homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7JH52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52/entry#names_and_taxonomy" } ] }, { "name": "Carnitine deficiency-associated protein expressed in ventricle 1", "type": "synonym", "evidence": [ { "id": "A0A9J7JH52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52/entry#names_and_taxonomy" } ] }, { "name": "intraflagellar transport protein 81 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027269841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269841" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027269841.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269841" } ] }, { "annotation": "Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis. Required for proper regulation of SHH signaling. Plays an important role during spermatogenesis by modulating the assembly and elongation of the sperm flagella.", "evidence": [ { "database": "UniProtKB", "id": "G3H240", "url": "https://www.uniprot.org/uniprotkb/G3H240#function" }, { "database": "UniProtKB", "id": "ARBA00055755", "url": "https://www.uniprot.org/uniprotkb/ARBA00055755#function" }, { "database": "UniProtKB", "id": "A0A9J7JH52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ift81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52", "locus": {} } ], "crossref": [ { "id": "A0A9J7JH52", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JH52", "database": "AlphaFoldDB", "categories": [] }, { "id": "100765323", "url": "https://www.ncbi.nlm.nih.gov/gene/100765323", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765323", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765323", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JH52", "url": "https://www.orthodb.org/?gene=A0A9J7JH52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3H240", "url": "https://www.orthodb.org/?gene=G3H240", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15614:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15614:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269841", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JH52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH52-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H240", "url": "https://www.uniprot.org/uniprotkb/G3H240", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H240-1", "url": "https://www.uniprot.org/uniprotkb/G3H240-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLAHGNRCQGAVSRNPESPGASRWVGRWFHEENLSFKLQDLIMSDQIKFIVDSLNKEPFKKNYNLITFDSLGPMQLLQVLNDVLAEIDPKQDVDIREEMPEQTAKRMLNLLGILKYKPPGNATDMSTFRQGLVIGSKPVIYPVLHWLLQRSNELKKRAYLARFLIKLEVPSEFLQDETVADTNKQYEELMEAFKTLHKECEQLKTSGFSTAEIRRDISAMEEEKDQLMKRVERLKKRVETVQNHQRMLKIARQLRVEKEREEFLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRHAAADAKPESLMKRLEEEIKFNSYMVTEKFPKELESKKKELHFLQKVVSEPAMGHSDLLELESKVNEINTEINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQETKEKLANLEREVSVKTNQTREFDGAEVLKGDEFKRYVSKLRSKSTVFKKKHQIIAEFKAEFGLLQRTEELLKQRQETIQHQLRTIEEKKGVSGYSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLNSLVSEKKSALAPVIKELRQLRQKCQELTQECDEKKAQYDSCAAGLESNRSKLEQEVRGLREECLQEESRYHYTNCVIKNLEVQLRRATDEMKAYVSSDQQEKRKAIREQYTKNITEQENLGKKLREKQKAVRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSQACIGQKPYMVVYTCQVRCWGD", "length": 723, "header": "tr|A0A9J7JH52-1|A0A9J7JH52_CRIGR Isoform 1 of Intraflagellar transport protein 81 homolog OS=Cricetulus griseus OX=10029 GN=Ift81 PE=3 SV=1 CANONICAL=A0A9J7JH52-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JH52-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52/entry#A0A9J7JH52-1", "sequence": { "sequence": "MTLAHGNRCQGAVSRNPESPGASRWVGRWFHEENLSFKLQDLIMSDQIKFIVDSLNKEPFKKNYNLITFDSLGPMQLLQVLNDVLAEIDPKQDVDIREEMPEQTAKRMLNLLGILKYKPPGNATDMSTFRQGLVIGSKPVIYPVLHWLLQRSNELKKRAYLARFLIKLEVPSEFLQDETVADTNKQYEELMEAFKTLHKECEQLKTSGFSTAEIRRDISAMEEEKDQLMKRVERLKKRVETVQNHQRMLKIARQLRVEKEREEFLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRHAAADAKPESLMKRLEEEIKFNSYMVTEKFPKELESKKKELHFLQKVVSEPAMGHSDLLELESKVNEINTEINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQETKEKLANLEREVSVKTNQTREFDGAEVLKGDEFKRYVSKLRSKSTVFKKKHQIIAEFKAEFGLLQRTEELLKQRQETIQHQLRTIEEKKGVSGYSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLNSLVSEKKSALAPVIKELRQLRQKCQELTQECDEKKAQYDSCAAGLESNRSKLEQEVRGLREECLQEESRYHYTNCVIKNLEVQLRRATDEMKAYVSSDQQEKRKAIREQYTKNITEQENLGKKLREKQKAVRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSQACIGQKPYMVVYTCQVRCWGD", "length": 723, "header": "tr|A0A9J7JH52-1|A0A9J7JH52_CRIGR Isoform 1 of Intraflagellar transport protein 81 homolog OS=Cricetulus griseus OX=10029 GN=Ift81 PE=3 SV=1 CANONICAL=A0A9J7JH52-1" }, "locus": {} }, { "isoform_ac": "G3H240-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52/entry#G3H240-1", "sequence": { "sequence": "MSDQIKFIVDSLNKEPFKKNYNLITFDSLGPMQLLQVLNDVLAEIDPKQDVDIREEMPEQTAKRMLNLLGILKYKPPGNATDMSTFRQGLVIGSKPVIYPVLHWLLQRSNELKKRAYLARFLIKLEVPSEFLQDETVADTNKQYEELMEAFKTLHKECEQLKTSGFSTAEIRRDISAMEEEKDQLMKRVERLKKRVETVQNHQRMLKIARQLRVEKEREEFLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRHAAADAKPESLMKRLEEEIKFNSYMVTEKFPKELESKKKELHFLQKVVSEPAMGHSDLLELESKVNEINTEINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQETKEKLANLEREVSVKTNQTREFDGAEVLKGDEFKRYVSKLRSKSTVFKKKHQIIAEFKAEFGLLQRTEELLKQRQETIQHQLRTIEEKKGVSGYSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLNSLVSEKKSALAPVIKELRQLRQKCQELTQECDEKKAQYDSCAAGLESNRSKLEQEVRGLREECLQEESRYHYTNCVIKNLEVQLRRATDEMKAYVSSDQQEKRKAIREQYTKNITEQENLGKKLREKQKAVRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSQACIGQKPYMVVYTCQVRCWGD", "length": 680, "header": "tr|G3H240-1|A0A9J7JH52_CRIGR Computationally mapped isoform of Intraflagellar transport protein 81 homolog OS=Cricetulus griseus OX=10029 GN=Ift81 PE=3 SV=1 CANONICAL=A0A9J7JH52-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H240", "url": "https://www.uniprot.org/uniprotkb/G3H240" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H240", "url": "https://www.uniprot.org/uniprotkb/G3H240" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765323", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765323", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52" } ], "pmid": "" }, { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52" } ], "pmid": "" }, { "name": "intraciliary transport particle B", "id": "GO:0030992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JH52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH52" }, { "id": "PF18383", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18383" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IFT81 calponin homology", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 169, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 585, "end_pos": 587 }, { "start_pos": 650, 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JKI6-1", "uniprot_ac": "A0A9J7JKI6", "uniprot_id": "A0A9J7JKI6_CRIGR", "mass": { "chemical_mass": 80733.0, "monoisotopic_mass": 80733.0 }, "refseq": { "ac": "XP_007627404", "name": "dixin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007627404" }, "gene_names": [ { "name": "Dixdc1", "type": "recommended", "evidence": [ { "id": "A0A9J7JKI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6" } ] }, { "name": "Dixdc1", "type": "synonym", "evidence": [ { "id": "XP_007627404", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007627404" } ] } ], "protein_names": [ { "name": "Dixin", "type": "recommended", "evidence": [ { "id": "A0A9J7JKI6", "database": "UniProtKB", "url": 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Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613694.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007627404", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007627404" } ] }, { "annotation": "Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10878:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007627404", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007627404", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FTD5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTQ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX89", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX89-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMG7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H2H4", "url": "https://www.uniprot.org/uniprotkb/G3H2H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H2H4-1", "url": "https://www.uniprot.org/uniprotkb/G3H2H4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSPSALTALPGSQSSDIAFWVLSLSAASCHTFDLFLECAIFYQQQLQAYVAWVNAQLKKRPSVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPSNQQEMKNNVERVLQFVASKKIRMHQTSAKDIVEGNLKSIMRLVLALAAHFKPGSSRTVSQGRDSRAPVQSHQPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIVPSEGIENRTDRTADETDSPLSRDWRPGSPGTYLETTWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIRSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLEERNRLLGEYKKELGQKDRLLQQQQAKLEEALRKLSDASYQQVDLERELEHKDVLLAHCMKREADEVTNYNSHNSQRNGFVLPVAGRGAASATHRGPQTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMESQKKQERKVRGRSLRTQASSEYRASWPPNSTLPHSQSSPAVSSTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEEDHREN", "length": 713, "header": "tr|A0A9J7JKI6-1|A0A9J7JKI6_CRIGR Isoform 1 of Dixin OS=Cricetulus griseus OX=10029 GN=Dixdc1 PE=3 SV=1 CANONICAL=A0A9J7JKI6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FTD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6/entry#A0A9J7FTD5-1", "sequence": { "sequence": "MPPSKQVVPSLEYMVMESGRPKILAQAGEKLSGVQLSPSNQQEMKNNVERVLQFVASKKIRMHQTSAKDIVEGNLKSIMRLVLALAAHFKPGSSRTVSQGRDSRAPVQSHQPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIVPSEGIENRTDRTADETDSPLSRDWRPGSPGTYLETTWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIRSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLEERNRLLGEYKKELGQKDRLLQQQQAKLEEALRKLSDASYQQVDLERELEHKDVLLAHCMKREADEVTNYNSHNSQRNGFVLPVAGRGAASATHRGPQTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMESQKKQERKVRGRSLRTQASSEYRASWPPNSTLPHSQSSPAVSSTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEEDHREN", "length": 652, "header": "tr|A0A9J7FTD5-1|A0A9J7JKI6_CRIGR Computationally mapped isoform of Dixin OS=Cricetulus griseus OX=10029 GN=Dixdc1 PE=3 SV=1 CANONICAL=A0A9J7JKI6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6/entry#A0A9J7FTQ8-1", "sequence": { "sequence": "MRSPSALTALPGSQSSDIAFWVLSLSAASCHTFDLFLECAIFYQQQLQAYVAWVNAQLKKRPSVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPSNQQEMKNNVERVLQFVASKKIRMHQTSAKDIVEGNLKSIMRLVLALAAHFKPGSSRTVSQGRDSRAPVQSHQPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIVPSEGIENRTDRTADETDSPLSRDWRPGSPGTYLETTWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIRSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNKELGQKDRLLQQQQAKLEEALRKLSDASYQQVDLERELEHKDVLLAHCMKREADEVTNYNSHNSQRNGFVLPVAGRGAASATHRGPQTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMESQKKQERKVRGRSLRTQASSEYRASWPPNSTLPHSQSSPAVSSTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEEDHREN", "length": 695, "header": "tr|A0A9J7FTQ8-1|A0A9J7JKI6_CRIGR Computationally mapped isoform of Dixin OS=Cricetulus griseus OX=10029 GN=Dixdc1 PE=3 SV=1 CANONICAL=A0A9J7JKI6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FV39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6/entry#A0A9J7FV39-1", "sequence": { "sequence": "MKNNVERVLQFVASKKIRMHQTSAKDIVEGNLKSIMRLVLALAAHFKPGSSRTVSQGRDSRAPVQSHQPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIVPSEGIENRTDRTADETDSPLSRDWRPGSPGTYLETTWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIRSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLEERNRLLGEYKKELGQKDRLLQQQQAKLEEALRKLSDASYQQVDLERELEHKDVLLAHCMKREADEVTNYNSHNSQRNGFVLPVAGRGAASATHRGPQTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMESQKKQERKVRGRSLRTQASSEYRASWPPNSTLPHSQSSPAVSSTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEEDHREN", "length": 609, "header": "tr|A0A9J7FV39-1|A0A9J7JKI6_CRIGR Computationally mapped isoform of Dixin OS=Cricetulus griseus OX=10029 GN=Dixdc1 PE=3 SV=1 CANONICAL=A0A9J7JKI6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FX89-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6/entry#A0A9J7FX89-1", "sequence": { "sequence": "MGGTQVKCLTSPSPIHSAKSESIITQSEEKADFVIVPSEGIENRTDRTADETDSPLSRDWRPGSPGTYLETTWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIRSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLEERNRLLGEYKKELGQKDRLLQQQQAKLEEALRKLSDASYQQVDLERELEHKDVLLAHCMKREADEVTNYNSHNSQRNGFVLPVAGRGAASATHRGPQTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMESQKKQERKVRGRSLRTQASSEYRASWPPNSTLPHSQSSPAVSSTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEEDHREN", "length": 478, "header": "tr|A0A9J7FX89-1|A0A9J7JKI6_CRIGR Computationally mapped isoform of Dixin OS=Cricetulus griseus OX=10029 GN=Dixdc1 PE=3 SV=1 CANONICAL=A0A9J7JKI6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6/entry#A0A9J7JKI6-1", "sequence": { "sequence": "MRSPSALTALPGSQSSDIAFWVLSLSAASCHTFDLFLECAIFYQQQLQAYVAWVNAQLKKRPSVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPSNQQEMKNNVERVLQFVASKKIRMHQTSAKDIVEGNLKSIMRLVLALAAHFKPGSSRTVSQGRDSRAPVQSHQPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIVPSEGIENRTDRTADETDSPLSRDWRPGSPGTYLETTWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIRSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLEERNRLLGEYKKELGQKDRLLQQQQAKLEEALRKLSDASYQQVDLERELEHKDVLLAHCMKREADEVTNYNSHNSQRNGFVLPVAGRGAASATHRGPQTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMESQKKQERKVRGRSLRTQASSEYRASWPPNSTLPHSQSSPAVSSTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEEDHREN", "length": 713, "header": "tr|A0A9J7JKI6-1|A0A9J7JKI6_CRIGR Isoform 1 of Dixin OS=Cricetulus griseus OX=10029 GN=Dixdc1 PE=3 SV=1 CANONICAL=A0A9J7JKI6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JMG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6/entry#A0A9J7JMG7-1", "sequence": { "sequence": "MRWKNVELRPGEEQANPQQLQAYVAWVNAQLKKRPSVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPSNQQEMKNNVERVLQFVASKKIRMHQTSAKDIVEGNLKSIMRLVLALAAHFKPGSSRTVSQGRDSRAPVQSHQPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIVPSEGIENRTDRTADETDSPLSRDWRPGSPGTYLETTWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIRSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLEERNRLLGEYKKELGQKDRLLQQQQAKLEEALRKLSDASYQQVDLERELEHKDVLLAHCMKREADEVTNYNSHNSQRNGFVLPVAGRGAASATHRGPQTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMESQKKQERKVRGRSLRTQASSEYRASWPPNSTLPHSQSSPAVSSTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEEDHREN", "length": 686, "header": "tr|A0A9J7JMG7-1|A0A9J7JMG7_CRIGR Computationally mapped isoform of Dixin OS=Cricetulus griseus OX=10029 GN=Dixdc1 PE=3 SV=1 CANONICAL=A0A9J7JKI6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6/entry#A0A9J7JNA2-1", "sequence": { "sequence": "MGTHVVMRVCNSTIPGTPSQQLQAYVAWVNAQLKKRPSVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPSNQQEMKNNVERVLQFVASKKIRMHQTSAKDIVEGNLKSIMRLVLALAAHFKPGSSRTVSQGRDSRAPVQSHQPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIVPSEGIENRTDRTADETDSPLSRDWRPGSPGTYLETTWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIRSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLEERNRLLGEYKKELGQKDRLLQQQQAKLEEALRKLSDASYQQVDLERELEHKDVLLAHCMKREADEVTNYNSHNSQRNGFVLPVAGRGAASATHRGPQTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMESQKKQERKVRGRSLRTQASSEYRASWPPNSTLPHSQSSPAVSSTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEEDHREN", "length": 688, "header": "tr|A0A9J7JNA2-1|A0A9J7JNA2_CRIGR Computationally mapped isoform of Dixin OS=Cricetulus griseus OX=10029 GN=Dixdc1 PE=3 SV=1 CANONICAL=A0A9J7JKI6-1" }, "locus": {} }, { "isoform_ac": "G3H2H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6/entry#G3H2H4-1", "sequence": { "sequence": "MLACLTRGNLLDVLQEGFNEQQLQAYVAWVNAQLKKRPSVKPVQDLRQDLRDGVILAYLIEIVAGEKLSGVQLSPSNQQEMKNNVERVLQFVASKKIRMHQTSAKDIVEGNLKSIMRLVLALAAHFKPGSSRTVSQGRDSRAPVQSHQPHCATAVAQGAAAALADVCHDMSRSGRDVFRYRQRNSSMDEEIENPYWSVRALVQQYEGQQRSPSESSCSSLTSPSPIHSAKSESIITQSEEKADFVIVPSEGIENRTDRTADETDSPLSRDWRPGSPGTYLETTWEEQLLEQQEHLEKEMEEAKKMISGLQALLLNGSLPEDEQERPLALCEPGVNPEEQLIIIRSRLDQSMEENQDLKKELLKCKQEARNLQGIKDALQQRLTQQDTSVLQLKQELLRANMDKDELHNQNVDLQRKLEERNRLLGEYKKELGQKDRLLQQQQAKLEEALRKLSDASYQQVDLERELEHKDVLLAHCMKREADEVTNYNSHNSQRNGFVLPVAGRGAASATHRGPQTSDLQLVRDALRSLRNSFSGHDPQHHTIDSLEQGISSLMERLHVMESQKKQERKVRGRSLRTQASSEYRASWPPNSTLPHSQSSPAVSSTCTKVLYFTDRSLTPFMVNIPKRLGEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEVFHDDDAIPGWEGKIVAWVEEDHREN", "length": 689, "header": "tr|G3H2H4-1|A0A9J7JKI6_CRIGR Computationally mapped isoform of Dixin OS=Cricetulus griseus OX=10029 GN=Dixdc1 PE=3 SV=1 CANONICAL=A0A9J7JKI6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H2H4", "url": "https://www.uniprot.org/uniprotkb/G3H2H4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H2H4", "url": "https://www.uniprot.org/uniprotkb/G3H2H4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773209", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773209", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JKI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 151, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JKI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKI6" }, { "id": "PS50841", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50841" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DIX", "eco_id": "ECO_0000259", "start_pos": 630, "end_pos": 710, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 208, "end_pos": 210 }, { "start_pos": 278, "end_pos": 280 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 614, "end_pos": 616 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GCU1-1", "uniprot_ac": "A0A9J7GCU1", "uniprot_id": "A0A9J7GCU1_CRIGR", "mass": { "chemical_mass": 95261.0, "monoisotopic_mass": 95261.0 }, "refseq": { "ac": "XP_007640360", "name": "telomere length regulation protein TEL2 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640360" }, "gene_names": [ { "name": "Telo2", "type": "recommended", "evidence": [ { "id": "A0A9J7GCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ] }, { "name": "Telo2", "type": "synonym", "evidence": [ { "id": "XP_007640360", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640360" } ] } ], "protein_names": [ { "name": "Telomere length regulation protein TEL2 homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7GCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1/entry#names_and_taxonomy" } ] }, { "name": "telomere length regulation protein TEL2 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007640360", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640360" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613852.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640360" } ] }, { "annotation": "Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.", "evidence": [ { "database": "UniProtKB", "id": "G3HBX8", "url": "https://www.uniprot.org/uniprotkb/G3HBX8#function" }, { "database": "UniProtKB", "id": "ARBA00053387", "url": "https://www.uniprot.org/uniprotkb/ARBA00053387#function" }, { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Telo2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCU1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100774669", "url": "https://www.ncbi.nlm.nih.gov/gene/100774669", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038528", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038528", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774669", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774669", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FYPQNYF", "url": "https://omabrowser.org/oma/group/FYPQNYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GCU1", "url": "https://www.orthodb.org/?gene=A0A9J7GCU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HBX8", "url": "https://www.orthodb.org/?gene=G3HBX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15830", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15830", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15830:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15830:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640360", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640360", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HBX8", "url": "https://www.uniprot.org/uniprotkb/G3HBX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HBX8-1", "url": "https://www.uniprot.org/uniprotkb/G3HBX8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRSPARRPSADSSRASPLSCKMDPALSAVRLTVQEAIHTLSSSEDVGHILSTLGTLKRYLGGTEDPALPEKEEFTTIHFSAILRCLVSKLSPGWLELSPDGQLEQLWESFFLDGPPDQAFLVLMEAIESTAGPSFRLMKMARLLEIFLSKGRVAALMEEQCRPQTKPSFPLFQETLLSKVVGLPDRLGNSLQQDNLTQFLPQNYFPLLGQEVVEVLKAVVNFLQGGLDCSVSFVSRVLGKVCIQGRKKEILGVLVPQLTVLTQDSCLWQRVCWRLVEQVPDRAVEAVLTGLVEAAPRPEVLSRLLGNLVVKNKKAQFVMTRKLLFLQYQHTTPMLQSLLGYLAVDSQRRPLLIQVLKELLETWGNSSAVRHAPLEQQCYISKAILVCLAHLGEPELQDIQDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVISSRIHPEGPPLKFQYEDDEMSREMLALATPGPAGACSSETGGPSLASVVTETPVETPEKTVDSDVPSVQPQGSDSELDSDDEFIPYDMSGDKELKSSKEPRYIRDCLEALTTSEDMERWEAALNVLEGLVYRSPEATREVSVELAKVLLHLEEKTCMAEFEQLRQRALVAVTVTDPEQVAKYLTTQFYGLNYSLRQRMDILDVLVLAAQALSRPRSLQRLSQHGPPGSGTLCAPALASSQPGNAATPDWQVVVEERIKSKTRRFSKGCPRRELTGGPNEFNSVAGYFFFPLLQHFDRPLVTFDLLGDDQLVLGRLAHTLASLMYLAVNTTVAVPMGKALLEFVWALRFHVDTYVRRGLLSAVSSVLLSVPTERLLGDLPDELLEARSWLADVAEKDVDEDCRELAMRALLLLERLRDKLLSISSP", "length": 859, "header": "tr|A0A9J7GCU1-1|A0A9J7GCU1_CRIGR Isoform 1 of Telomere length regulation protein TEL2 homolog OS=Cricetulus griseus OX=10029 GN=Telo2 PE=3 SV=1 CANONICAL=A0A9J7GCU1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1/entry#A0A9J7GCU1-1", "sequence": { "sequence": "MLRSPARRPSADSSRASPLSCKMDPALSAVRLTVQEAIHTLSSSEDVGHILSTLGTLKRYLGGTEDPALPEKEEFTTIHFSAILRCLVSKLSPGWLELSPDGQLEQLWESFFLDGPPDQAFLVLMEAIESTAGPSFRLMKMARLLEIFLSKGRVAALMEEQCRPQTKPSFPLFQETLLSKVVGLPDRLGNSLQQDNLTQFLPQNYFPLLGQEVVEVLKAVVNFLQGGLDCSVSFVSRVLGKVCIQGRKKEILGVLVPQLTVLTQDSCLWQRVCWRLVEQVPDRAVEAVLTGLVEAAPRPEVLSRLLGNLVVKNKKAQFVMTRKLLFLQYQHTTPMLQSLLGYLAVDSQRRPLLIQVLKELLETWGNSSAVRHAPLEQQCYISKAILVCLAHLGEPELQDIQDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVISSRIHPEGPPLKFQYEDDEMSREMLALATPGPAGACSSETGGPSLASVVTETPVETPEKTVDSDVPSVQPQGSDSELDSDDEFIPYDMSGDKELKSSKEPRYIRDCLEALTTSEDMERWEAALNVLEGLVYRSPEATREVSVELAKVLLHLEEKTCMAEFEQLRQRALVAVTVTDPEQVAKYLTTQFYGLNYSLRQRMDILDVLVLAAQALSRPRSLQRLSQHGPPGSGTLCAPALASSQPGNAATPDWQVVVEERIKSKTRRFSKGCPRRELTGGPNEFNSVAGYFFFPLLQHFDRPLVTFDLLGDDQLVLGRLAHTLASLMYLAVNTTVAVPMGKALLEFVWALRFHVDTYVRRGLLSAVSSVLLSVPTERLLGDLPDELLEARSWLADVAEKDVDEDCRELAMRALLLLERLRDKLLSISSP", "length": 859, "header": "tr|A0A9J7GCU1-1|A0A9J7GCU1_CRIGR Isoform 1 of Telomere length regulation protein TEL2 homolog OS=Cricetulus griseus OX=10029 GN=Telo2 PE=3 SV=1 CANONICAL=A0A9J7GCU1-1" }, "locus": {} }, { "isoform_ac": "G3HBX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1/entry#G3HBX8-1", "sequence": { "sequence": "MDPALSAVRLTVQEAIHTLSSSEDVGHILSTLGTLKRYLGGTEDPALPEKEEFTTIHFSAILRCLVSKLSPGWLELSPDGQLEQLWESFFLDGPPDQAFLVLMEAIESTAGPSFRLMKMARLLEIFLSKGRVAALMEEQCRPQTKPSFPLFQETLLSKVVGLPDRLGNSLQQDNLTQFLPQNYFPLLGQEVVEVLKAVVNFLQGGLDCSVSFVSRVLGKVCIQGRKKEILGVLVPQLTVLTQDSCLWQRVCWRLVEQVPDRAVEAVLTGLVEAAPRPEVLSRLLGNLVVKNKKAQFVMTRKLLFLQYQHTTPMLQSLLGYLAVDSQRRPLLIQVLKELLETWGNSSAVRHAPLEQQCYISKAILVCLAHLGEPELQDIQDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVISSRIHPEGPPLKFQYEDDEMSREMLALATPGPAGACSSETGGPSLASVVTETPVETPEKTVDSDVPSVQPQGSDSELDSDDEFIPYDMSGDKELKSSKEPRYIRDCLEALTTSEDMERWEAALNVLEGLVYRSPEATREVSVELAKVLLHLEEKTCMAEFEQLRQRALVAVTVTDPEQVAKYLTTQFYGLNYSLRQRMDILDVLVLAAQALSRPRSLQRLSQHGPPGSGTLCAPALASSQPGNAATPDWQVVVEERIKSKTRRFSKGCPRRELTGGPNEFNSVAGYFFFPLLQHFDRPLVTFDLLGDDQLVLGRLAHTLASLMYLAVNTTVAVPMGKALLEFVWALRFHVDTYVRRGLLSAVSSVLLSVPTERLLGDLPDELLEARSWLADVAEKDVDEDCRELAMRALLLLERLRDKLLSISSP", "length": 837, "header": "tr|G3HBX8-1|A0A9J7GCU1_CRIGR Computationally mapped isoform of Telomere length regulation protein TEL2 homolog OS=Cricetulus griseus OX=10029 GN=Telo2 PE=3 SV=1 CANONICAL=A0A9J7GCU1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 680, "start_aa": "Thr", "end_pos": 680, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr680", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HBX8", "url": "https://www.uniprot.org/uniprotkb/G3HBX8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HBX8", "url": "https://www.uniprot.org/uniprotkb/G3HBX8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774669", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774669", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1I9LMG5-1", "protein_name": "Embryo defective 2423", "gene_name": "EMB2423", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEGTKQERTLENNLLHKVGEAVSAISDAKHVDQVISAIHSVAVLLFPVDPSLFSGSIGDKYRERVCSSVVPSADERNEWLETFYRGVAFPTFARVLLLDVASDWLSCFPISVQKHLYDKFFLDGSVIEVVQVLVPFLHHVGDGGVNANSVQTNVERLLILCLLENDGVLKITKEIGNIYQGHNSSNGSLKPLLSRLSQILTSIPDKARLKSPPLLSSNLYFKHITNQLLQILDDRASCTEANCTVIVLSFVGEVFSRICRRGLSDLLLSEVTPHVLAQVRRLLNSKIGAIEVDTFQLDPTTRIWSKTMEAVTDPYAVEKMAEQLLHQLYAEHPSDVEAFWTIWTLFHRNVIHQASVRSIFVDKFLLWKVFPIRCLRWILQFSVLECPPVTNTLAKGDVTQGLLETTQRLASVWSKREFLQSVQLEQQAYITAALGLCLENMSREELDRTKDVMHSILQGVSCRLENPGDLVRKMASSIAFMFSKVIDPKNPLYLDDSITDNAIDWEFGLQTASITNTMENGDGENKRSASLTEVNESSRRNKQKENRKSKNISAFVLADPNEIVDLATLNCDTESDKDDGDDDASVSSDNSSVTSLEPYDLMDDDKDLGKQFTHLVDVVGALRKTDDADGVEKAIYVAEKLVRASPDELTHIAGDLARTLVQVRCSDIAIEGEEDSAEEKRQRALIALLVTRPFESLETLNNILYSPNVDVSQRIMILDVMAEAARELANSKTLKPKHEARGPLISNISDPQPWYLPSNASTPWKKVSETGSFHLNWANRFERELQSKPGQTKKGKSRRWSLKSADRDQNSTDWSQNRFPLYAAAFMLPAMKEFDKKRHGVDLLGRDFVVLGKLVHMLGVCMQCASMHPEASALAISLLDMLQRREVCNHPEAYVRRAVLFAASSVLVSLHPSYIVSTLVEGNLDLSRALEWIRTWALQIADSDIDRDCYTMALSCLQLHAEMALQTSRALESTGGSSSSSSIRPMNISLPSGISKLTSIKLPSSNVHL", "length": 1010 }, "evidence": [ { "id": "A0A9J7GCU1", "url": "https://omabrowser.org/oma/group/A0A9J7GCU1/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A8V0Z0P5-1", "protein_name": "Telomere length regulation protein TEL2 homolog", "gene_name": "TELO2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAALESALQAAGAGPCPGAEAVGAVRAALAAAGDPAALGERERARLGAFLRNLAAGPEEPAGPWRSLFLESPPDLAFCALTDSLAAPRPGWRLPAVPEVLEQFLRQGRLAALICELCQQHSRPGSVERHDALLGRIVCLPDLVGNGLQGRSPAAFFPQRYFPVLGGAVLQVLHNVSASLRGGLDCSVSFISHILGKVCVHGRQKEILSVLVPHLTDLTKSDCIWQRICWRLVECVPDRWMEAVVLGFVQRAPGADVLSRLLGNLVVKNKKAQFVVTQKMLLLQYGYTTAVLQNLLGYLALDGLRRALLIKVLQELLETWSSSSAVKHSPLEQQQYISKAILICLSHLKEPEIESCRQELLTSMMEGVKCHLDSSLPQIRRLGMIVAESISSKINTDGPVLTFQYEEDDEARELKSLLVQAAPLGVLPGLPDNDRNENADAALPPVLESNRKSTTATTHVMPDEESDAELDSDDDLIPYDMSEDKELKKTKAPVYIRDCIEVLTGSEDLDKWEEAVKALESLVRKNPVAAREVSVELAKILLHLEEKTCLEGFAELRQKAQVAVLTTDPIPVAQYLTSQFYSLNYSLRQRMDILDVLVLAARELSCPKGHGKTKHSGAQNPCIQFLPESGSSKDWRRIVDERIKSKTRRFAKGQSQVEQPSGPNEFNSLAGHFFFPLIQNFDRPLSTFDLLGEDHFVLGRLVHTLAVLMYLAVNTMAVTAMGKALLEFVWALRFHTDSYVRQGLLSCVSSILLSVPAERLLQDVTEELLETRSWLEDVVEKDPDGDCRRLALQNLLLMENLKKKLETAPS", "length": 810 }, "evidence": [ { "id": "A0A9J7GCU1", "url": "https://omabrowser.org/oma/group/A0A9J7GCU1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZQ30-1", "protein_name": "Telomere length regulation protein TEL2 homolog", "gene_name": "Telo2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPALSAVRLTVQEAIHTLSSSEDAGHILSTLGTLKRYLGRTEDPVLPEEKEEFATVHFSAVLRCLVSKLSPGWLELSPDGQLEQLWESFFLDGPPDQAFLVLMEAIESTAGPSFRLMKMARLLDTFLHAGRVAALMEEQCRPQTKPSFPLFQETLLSKVVGLPDLLGNRLQRDNLTQFFPQNYFPLLGLEVMRALKAAVNFLQVLLSVSGGLDCSVSFVSQVLGKVCIQGRKKEILGVLVPQLTVLTQDSCLWQRVCWRLVEQVPDRAVEAVLTGLVEAAPRPEVLSRLLGNLVVKNKKARFVMTRKLLFLQYQHTTPMVQSLLGYLALDSQRRPLLIQVLKELLETWGSSSAVRHAPLEQQCYISKAILVCMAHLGESELQDVRDELLASMMAGVKCRLDSSLPPVRRLGMVVAEVISSRIHPEGPPLKFQYEDDEMSRELLALAAPGPASDCSLEARGPSPAPVATEPPVETPEKTMESDVHPAQPQGSDSELDSDDEFIPYDMSGDKELKSSKEPLYIRDCVEALTTSEDIERWEASLKVLEGLVYRNPQATREVSVELAKVLLHLEEKTCVAEFEQLRQRALVAVTVTDPEQVAKYLTSQFYGLNYSLRQRMDILDVLVLAAQALSRPRSLQRLSQHSSPASGTSRSPALAISQPDWQVVVEERIRSKTRRFSKGCPRREVSGVPNEFNSVAGYFFFPLLQHFDRPLVTFDLLGDDQLVLGRLTHTLASLMYLAVNTTVAVPMGKALLEFVWALRFHVDIYVRRGLLSAVSSVLLSVPTERLLGDLPDELLEARSWLADVAERDVDEDCRELAVRSLLLLERLKDKLLSSCSPQP", "length": 840 }, "evidence": [ { "id": "A0A9J7GCU1", "url": "https://omabrowser.org/oma/group/A0A9J7GCU1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B7I8-1", "protein_name": "Telomere length regulation protein TEL2 homolog", "gene_name": "TELO2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPVASAVRLAVQEAVHILSSSEDGGHIISTLQSLRRYLGETETQAPPEEQEEFSRTHFSTILRCLVGKLSPDWLDLLPDGQLEELWASFFLEGPADQAFLVLMESIEGAASPSFRLMKMARLLARFLSAGRMAAVMEGQCGQQAGPASRLLQETLLTRVVGLPDHLGNRLQRETLAAFFPQNYFPLLGEEVLRVLQAVVDSLRGGLDCSVSFLSQVLGKACVHGRQKEILDVLVPRLTVLTQGNCLWQRVCWRLVECVPDRAMEAVLKGLVEAAPGPEVLSRLLGNLVTKSKKAQFVMTQKLLFLQYSCSMPMLQSLLGYLAMDSQRRPLLVQALKELLETWGSSSAIRHTPLEQQRYVSKALLICLTHLGEAELRASRDELLASLMEGVKSRLDSSLPPVRRLGMIVAEVASARLHPEGPPLKFQYEEDELTREMLALAVPRPAADGPSEAGPPVAPVSGEFPDQETVDSGGPQAGWEGSDSELDSDDELVPYDMSGDGEQRGSKTPAYVRDCLEALTASEDWERWEEALRALEGLVLKSPAATREVSLELAKVLLHLEEKTAVAGFERLRQRALVAVTVTDPARVAEYLAVQFYALNYSLRQRMDILDVLALAAQELSRPGRLGKAAQRGSPGPGSQPSGAAVPAWKAVVEERVRRKTRRFCKQGSTGRAAAAGPNEFNAVAGYFFFPLLQRFDRPVVTFDLLGDDQLVLGRLAHTLGALMYLAVNTAVAVPMGKALLEFVWALRFHGDAYVRRGLLSAVSSVLLSVPAEWLLADLPDELLEARSWLADVAEQDADEDCRLLAVKALLLLEKLRDRLLPLSSP", "length": 826 }, "evidence": [ { "id": "A0A9J7GCU1", "url": "https://omabrowser.org/oma/group/A0A9J7GCU1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9DC40-1", "protein_name": "Telomere length regulation protein TEL2 homolog", "gene_name": "Telo2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPALSAVRLTVQEAIHILSSSEDAGHILSTLGTLKRYLGGTEDPVLPEEKEEFATVHFSAVLRCLVSKLSPGWLELSPGGQLERLWESFFLDGPPDQAFLVLMEAIESTAGPSFRLMKMAQLLDTFLSTGRVAALMEEQCRPQTKPSFPLFQETLLSKVVGLPDLLGNCLQRDNLTQFFPQNYFPLLGQEVVQALKAVVNFLQDGLDCSVSFVSRVLGKVCIQGRKREILSVLVPQLTVLTQDSCLWQRVCWRLVEQVPDRAVEAVLTGLVEAAPRPEVLSRLLGNLVVKNKKARFVVTRKLLLLQYQHTTPMVQSLLGYLALDSQRRPLLIQVLKELLETWGCSSAVRHTPLEQQCYISKAILVCLAHLGEPELQDIRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVISSRIHPEGPLLKFQYEDDEMSRELLALATPEPAGDCSSVSRGPSPAPVDTESPVEMPEKAVESDVPPTQPQGSDSELDSDDEFIPYDMSGDRELKSSKEPLYIRDCVEALTTSEDMERWEASLKGLEGLVYRSPTATREVSVELAKVLLHLEEKTCVAEFEQLRQSALVAVTVTDPEQVAKYLTSQFYGLNYSLRQRMDILDVLVLAAQALSRPKSLQRRSQHGPPVPGTMCSPALAVSQTGNVAAPDWQVVVEERIRSKTRRFSKGCPQRELSGVPNEFSSVAGYFFFPLLQHFDRPLVTFDLLGDDQLVLGRLTHTLASLMYLAVNTTVAVPMGKALLEFVWALRFHVDIYVRRGLLSAVSSVLLSVPTERLLGDLPDELLEARSWLADVAEKDVDEDCRELAVRALLLLERLKDKLLSSSSPQP", "length": 840 }, "evidence": [ { "id": "A0A9J7GCU1", "url": "https://omabrowser.org/oma/group/A0A9J7GCU1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y4R8-1", "protein_name": "Telomere length regulation protein TEL2 homolog", "gene_name": "TELO2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPAPSEVRLAVREAIHALSSSEDGGHIFCTLESLKRYLGEMEPPALPREKEEFASAHFSPVLRCLASRLSPAWLELLPHGRLEELWASFFLEGPADQAFLVLMETIEGAAGPSFRLMKMARLLARFLREGRLAVLMEAQCRQQTQPGFILLRETLLGKVVALPDHLGNRLQQENLAEFFPQNYFRLLGEEVVRVLQAVVDSLQGGLDSSVSFVSQVLGKACVHGRQQEILGVLVPRLAALTQGSYLHQRVCWRLVEQVPDRAMEAVLTGLVEAALGPEVLSRLLGNLVVKNKKAQFVMTQKLLFLQSRLTTPMLQSLLGHLAMDSQRRPLLLQVLKELLETWGSSSAIRHTPLPQQRHVSKAVLICLAQLGEPELRDSRDELLASMMAGVKCRLDSSLPPVRRLGMIVAEVVSARIHPEGPPLKFQYEEDELSLELLALASPQPAGDGASEAGTSLVPATAEPPAETPAEIVDGGVPQAQLAGSDSDLDSDDEFVPYDMSGDRELKSSKAPAYVRDCVEALTTSEDIERWEAALRALEGLVYRSPTATREVSVELAKVLLHLEEKTCVVGFAGLRQRALVAVTVTDPAPVADYLTSQFYALNYSLRQRMDILDVLTLAAQELSRPGCLGRTPQPGSPSPNTPCLPEAAVSQPGSAVASDWRVVVEERIRSKTQRLSKGGPRQGPAGSPSRFNSVAGHFFFPLLQRFDRPLVTFDLLGEDQLVLGRLAHTLGALMCLAVNTTVAVAMGKALLEFVWALRFHIDAYVRQGLLSAVSSVLLSLPAARLLEDLMDELLEARSWLADVAEKDPDEDCRTLALRALLLLQRLKNRLLPPASP", "length": 837 }, "evidence": [ { "id": "A0A9J7GCU1", "url": "https://omabrowser.org/oma/group/A0A9J7GCU1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "'de novo' cotranslational protein folding", "id": "GO:0051083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051083", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" }, { "name": "protein stabilization", "id": "GO:0050821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050821", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "molecular adaptor activity", "id": "GO:0060090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" }, { "name": "telomeric DNA binding", "id": "GO:0042162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042162", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" }, { "name": "protein-containing complex binding", "id": "GO:0044877", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044877", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" }, { "name": "protein-containing complex stabilizing activity", "id": "GO:0140777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140777", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 625, "end_pos": 627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" }, { "id": "PF25320", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25320" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TELO2 ARM repeat", "eco_id": "ECO_0000259", "start_pos": 346, "end_pos": 457, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7GCU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU1" }, { "id": "PF10193", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10193" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Telomere length regulation protein conserved", "eco_id": "ECO_0000259", "start_pos": 534, "end_pos": 642, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 680 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 625, "end_pos": 627 }, { "start_pos": 762, "end_pos": 764 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDG6-1", "uniprot_ac": "A0A9J7GDG6", "uniprot_id": "A0A9J7GDG6_CRIGR", "mass": { "chemical_mass": 106237.0, "monoisotopic_mass": 106237.0 }, "refseq": { "ac": "XP_027283465", "name": "zinc finger protein 62 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283465" }, "gene_names": [ { "name": "Zfp62", "type": "recommended", "evidence": [ { "id": "A0A9J7GDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6" } ] }, { "name": "Zfp62", "type": "synonym", "evidence": [ { "id": "XP_027283465", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283465" } ] } ], "protein_names": [ { "name": "Zinc finger protein 62 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7GDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 62 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027283465", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283465" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283465", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283465" } ] }, { "annotation": "May play a role in differentiating skeletal muscle.", "evidence": [ { "database": "UniProtKB", "id": "G3HK14", "url": "https://www.uniprot.org/uniprotkb/G3HK14#function" }, { "database": "UniProtKB", "id": "ARBA00059052", "url": "https://www.uniprot.org/uniprotkb/ARBA00059052#function" }, { "database": "UniProtKB", "id": "A0A9J7GDG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zfp62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6", "locus": {} } ], "crossref": [ { "id": "A0A9J7GDG6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GDG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100770543", "url": "https://www.ncbi.nlm.nih.gov/gene/100770543", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770543", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770543", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDG6", "url": "https://www.orthodb.org/?gene=A0A9J7GDG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HK14", "url": "https://www.orthodb.org/?gene=G3HK14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376:SF210", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376:SF210", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283465", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283465", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GDG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HK14", "url": "https://www.uniprot.org/uniprotkb/G3HK14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HK14-1", "url": "https://www.uniprot.org/uniprotkb/G3HK14-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHLKTSMEDEESAKTSESNSEADSQCTSVEILHKDHIQKFKIGDTCDWVEKQLERPEWKVMKEDKSSTREKIDKSKSTENIKIEQDDETSEKSLYPSVNTIYQTIPTEPIISEQGEHEENINGNMHPTPQQKSAVKKSHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCRGTFRSSSSLRVHKRIHTGEKPYKCDECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDICGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFSYNSLLLQHKTIHTGERPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDVCGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITYRTLLNHKKIHLGEKPYKCDVCEKSFNYTSLLSQHKRVHTREKPFECDRCEKVFRNNSSLKVHKRIHTGEKPYECDVCGKAYISHSSLINHKSTHPGKTPYTCDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDWCGKAFRNSSGLTVHKRIHTGEKPYGCDECGKAYISHSSLINHKSVHRGKQPYNCECGKSFNYRSVLDQHKRIHTGKKPYRCNDCGKAFNIRSNLTKHKRIHTGEESLSMANMESHSGHFQKIIYYEGENALDGTRMRMPMPIWEAQPNKSQRNQIEETFYECKNF", "length": 925, "header": "tr|A0A9J7GDG6-1|A0A9J7GDG6_CRIGR Isoform 1 of Zinc finger protein 62 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=Zfp62 PE=3 SV=1 CANONICAL=A0A9J7GDG6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GDG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6/entry#A0A9J7GDG6-1", "sequence": { "sequence": "MSHLKTSMEDEESAKTSESNSEADSQCTSVEILHKDHIQKFKIGDTCDWVEKQLERPEWKVMKEDKSSTREKIDKSKSTENIKIEQDDETSEKSLYPSVNTIYQTIPTEPIISEQGEHEENINGNMHPTPQQKSAVKKSHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCRGTFRSSSSLRVHKRIHTGEKPYKCDECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDICGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFSYNSLLLQHKTIHTGERPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDVCGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITYRTLLNHKKIHLGEKPYKCDVCEKSFNYTSLLSQHKRVHTREKPFECDRCEKVFRNNSSLKVHKRIHTGEKPYECDVCGKAYISHSSLINHKSTHPGKTPYTCDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDWCGKAFRNSSGLTVHKRIHTGEKPYGCDECGKAYISHSSLINHKSVHRGKQPYNCECGKSFNYRSVLDQHKRIHTGKKPYRCNDCGKAFNIRSNLTKHKRIHTGEESLSMANMESHSGHFQKIIYYEGENALDGTRMRMPMPIWEAQPNKSQRNQIEETFYECKNF", "length": 925, "header": "tr|A0A9J7GDG6-1|A0A9J7GDG6_CRIGR Isoform 1 of Zinc finger protein 62 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=Zfp62 PE=3 SV=1 CANONICAL=A0A9J7GDG6-1" }, "locus": {} }, { "isoform_ac": "G3HK14-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6/entry#G3HK14-1", "sequence": { "sequence": "MEDEESAKTSESNSEADSQCTSVEILHKDHIQKFKIGDTCDWVEKQLERPEWKVMKEDKSSTREKIDKSKSTENIKIEQDDETSEKSLYPSVNTIYQTIPTEPIISEQGEHEENINGNMHPTPQQKSAVKKSHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCRGTFRSSSSLRVHKRIHTGEKPYKCDECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDICGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFSYNSLLLQHKTIHTGERPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDVCGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITYRTLLNHKKIHLGEKPYKCDVCEKSFNYTSLLSQHKRVHTREKPFECDRCEKVFRNNSSLKVHKRIHTGEKPYECDVCGKAYISHSSLINHKSTHPGKTPYTCDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDWCGKAFRNSSGLTVHKRIHTGEKPYGCDECGKAYISHSSLINHKSVHRGKQPYNCECGKSFNYRSVLDQHKRIHTGKKPYRCNDCGKAFNIRSNLTKHKRIHTGEESLSMANMESHSGHFQKIIYYEGENALDGTRMRMPMPIWEAQPNKSQRNQIEETFYECKNF", "length": 918, "header": "tr|G3HK14-1|A0A9J7GDG6_CRIGR Computationally mapped isoform of Zinc finger protein 62 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=Zfp62 PE=3 SV=1 CANONICAL=A0A9J7GDG6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HK14", "url": "https://www.uniprot.org/uniprotkb/G3HK14" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HK14", "url": "https://www.uniprot.org/uniprotkb/G3HK14" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770543", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770543", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 655, "end_pos": 657, "annotation": "n_glycosylation_sequon" }, { "start_pos": 656, "end_pos": 658, "annotation": "n_glycosylation_sequon" }, { "start_pos": 767, "end_pos": 769, "annotation": "n_glycosylation_sequon" }, { "start_pos": 853, "end_pos": 855, "annotation": "n_glycosylation_sequon" }, { "start_pos": 908, "end_pos": 910, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GDG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 140, "end_pos": 167, "start_aa": "His", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 655, "end_pos": 657 }, { "start_pos": 656, "end_pos": 658 }, { "start_pos": 767, "end_pos": 769 }, { "start_pos": 853, "end_pos": 855 }, { "start_pos": 908, "end_pos": 910 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JJ14-1", "uniprot_ac": "A0A9J7JJ14", "uniprot_id": "A0A9J7JJ14_CRIGR", "mass": { "chemical_mass": 89409.0, "monoisotopic_mass": 89409.0 }, "refseq": { "ac": "XP_027265779", "name": "protein tyrosine phosphatase domain-containing protein 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265779" }, "gene_names": [ { "name": "Ptpdc1", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14" } ] }, { "name": "Ptpdc1", "type": "synonym", "evidence": [ { "id": "XP_027265779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265779" } ] } ], "protein_names": [ { "name": "Protein tyrosine phosphatase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14/entry#names_and_taxonomy" } ] }, { "name": "protein tyrosine phosphatase domain-containing protein 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027265779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265779" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265779" } ] }, { "annotation": "May play roles in cilia formation and/or maintenance.", "evidence": [ { "database": "UniProtKB", "id": "G3GUH5", "url": "https://www.uniprot.org/uniprotkb/G3GUH5#function" }, { "database": "UniProtKB", "id": "ARBA00056295", "url": "https://www.uniprot.org/uniprotkb/ARBA00056295#function" }, { "database": "UniProtKB", "id": "A0A9J7JJ14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14#function" }, { "database": "UniProtKB", "id": "A0A9J7GXG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXG5#function" }, { "database": "UniProtKB", "id": "A0A9J7GYR6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYR6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptpdc1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14", "locus": {} } ], "crossref": [ { "id": "A0A9J7JJ14", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JJ14", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14506", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14506", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758995", "url": "https://www.ncbi.nlm.nih.gov/gene/100758995", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758995", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758995", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNERDPV", "url": "https://omabrowser.org/oma/group/CNERDPV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JJ14", "url": "https://www.orthodb.org/?gene=A0A9J7JJ14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265779", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GXG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYR6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7I0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3GUH5", "url": "https://www.uniprot.org/uniprotkb/G3GUH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3GUH5-1", "url": "https://www.uniprot.org/uniprotkb/G3GUH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQMQDPSRRPSAVHFLSAFLQGRRHSTSDPVLRLQQARRGSGSATKLLSSSSLQVMVAVSSVNRTEGNPTFPERKKNSERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWVTDSILAMARPSSELLEKYHIIEQFLSHGIKTIINLQRPGEHASCGNSLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTAILDMVKVMTFALQEGKVAVHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLAPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKYVPKIIHLVCKLLLDLAENRPVVVKSQLEGPGLSAEIEKTVSEMVTMQLDQELLRQNSDAPDPFDPTAVVAEFENQDVSLSNEQDFDPLWKRRDAESLQPLTHLKRQLSYSDSDLKRAKAILEQGETPWTVPAQDLLGHSLQHQAQISNCFIPPTSELGLNKEALVHSTFSFWTQSKCRGLEGLKDNGSPLFCRKDIPKEVQRSRTFSVGISCPHNPGEPVTPNFAGVHMEPEQVTHSHCEAPSGWVPGSVQEDGRTPCSPLNCGSSPKSQCPHVQESQGSSSLLEAMPDDGFQSELSAEARRILAAKALANLKEFVEKEEVKRKVEMWQKELNSREGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRQADAGEALFLLEKGQYQTILCVLHCIVSLQTLPVEVEEACLSHAIKAFTKVSFDSEDGPIVYNTLKKIFKHTLEEKRKMAKDSPRPGLS", "length": 799, "header": "tr|A0A9J7JJ14-1|A0A9J7JJ14_CRIGR Isoform 1 of Protein tyrosine phosphatase domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ptpdc1 PE=3 SV=1 CANONICAL=A0A9J7JJ14-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GXG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14/entry#A0A9J7GXG5-1", "sequence": { "sequence": "MLQTWMVMVAVSSVNRTEGNPTFPERKKNSERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWVTDSILAMARPSSELLEKYHIIEQFLSHGIKTIINLQRPGEHASCGNSLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTAILDMVKVMTFALQEGKVAVHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLAPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKYVPKIIHLVCKLLLDLAENRPVVVKSQLEGPGLSAEIEKTVSEMVTMQLDQELLRQNSDAPDPFDPTAVVAEFENQDVSLSNEQDFDPLWKRRDAESLQPLTHLKRQLSYSDSDLKRAKAILEQGETPWTVPAQDLLGHSLQHQAQISNCFIPPTSELGLNKEALVHSTFSFWTQSKCRGLEGLKDNGSPLFCRKDIPKEVQRSRTFSVGISCPHNPGEPVTPNFAGVHMEPEQVTHSHCEAPSGWVPGSVQEDGRTPCSPLNCGSSPKSQCPHVQESQGSSSLLEAMPDDGFQSELSAEARRILAAKALANLKEFVEKEEVKRKVEMWQKELNSREGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRQADAGEALFLLEKGQYQTILCVLHCIVSLQTLPVEVEEACLSHAIKAFTKVSFDSEDGPIVYNTLKKIFKHTLEEKRKMAKDSPRPGLS", "length": 751, "header": "tr|A0A9J7GXG5-1|A0A9J7GXG5_CRIGR Computationally mapped isoform of Protein tyrosine phosphatase domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ptpdc1 PE=3 SV=1 CANONICAL=A0A9J7JJ14-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14/entry#A0A9J7GYR6-1", "sequence": { "sequence": "MACSMACGGRACKYENPARWSEQEQAIKGVYSSWVTDSILAMARPSSELLEKYHIIEQFLSHGIKTIINLQRPGEHASCGNSLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTAILDMVKVMTFALQEGKVAVHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLAPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKYVPKIIHLVCKLLLDLAENRPVVVKSQLEGPGLSAEIEKTVSEMVTMQLDQELLRQNSDAPDPFDPTAVVAEFENQDVSLSNEQDFDPLWKRRDAESLQPLTHLKRQLSYSDSDLKRAKAILEQGETPWTVPAQDLLGHSLQHQAQISNCFIPPTSELGLNKEALVHSTFSFWTQSKCRGLEGLKDNGSPLFCRKDIPKEVQRSRTFSVGISCPHNPGEPVTPNFAGVHMEPEQVTHSHCEAPSGWVPGSVQEDGRTPCSPLNCGSSPKSQCPHVQESQGSSSLLEAMPDDGFQSELSAEARRILAAKALANLKEFVEKEEVKRKVEMWQKELNSREGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRQADAGEALFLLEKGQYQTILCVLHCIVSLQTLPVEVEEACLSHAIKAFTKVSFDSEDGPIVYNTLKKIFKHTLEEKRKMAKDSPRPGLS", "length": 700, "header": "tr|A0A9J7GYR6-1|A0A9J7GYR6_CRIGR Computationally mapped isoform of Protein tyrosine phosphatase domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ptpdc1 PE=3 SV=1 CANONICAL=A0A9J7JJ14-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ14-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14/entry#A0A9J7JJ14-1", "sequence": { "sequence": "MQMQDPSRRPSAVHFLSAFLQGRRHSTSDPVLRLQQARRGSGSATKLLSSSSLQVMVAVSSVNRTEGNPTFPERKKNSERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWVTDSILAMARPSSELLEKYHIIEQFLSHGIKTIINLQRPGEHASCGNSLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTAILDMVKVMTFALQEGKVAVHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLAPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKYVPKIIHLVCKLLLDLAENRPVVVKSQLEGPGLSAEIEKTVSEMVTMQLDQELLRQNSDAPDPFDPTAVVAEFENQDVSLSNEQDFDPLWKRRDAESLQPLTHLKRQLSYSDSDLKRAKAILEQGETPWTVPAQDLLGHSLQHQAQISNCFIPPTSELGLNKEALVHSTFSFWTQSKCRGLEGLKDNGSPLFCRKDIPKEVQRSRTFSVGISCPHNPGEPVTPNFAGVHMEPEQVTHSHCEAPSGWVPGSVQEDGRTPCSPLNCGSSPKSQCPHVQESQGSSSLLEAMPDDGFQSELSAEARRILAAKALANLKEFVEKEEVKRKVEMWQKELNSREGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRQADAGEALFLLEKGQYQTILCVLHCIVSLQTLPVEVEEACLSHAIKAFTKVSFDSEDGPIVYNTLKKIFKHTLEEKRKMAKDSPRPGLS", "length": 799, "header": "tr|A0A9J7JJ14-1|A0A9J7JJ14_CRIGR Isoform 1 of Protein tyrosine phosphatase domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ptpdc1 PE=3 SV=1 CANONICAL=A0A9J7JJ14-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K7I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14/entry#A0A9J7K7I0-1", "sequence": { "sequence": "MQMQDPSRRPSAVHFLSAFLQGRRHSTSDPVLRLQQARRGSGSATKLLSSSSLQVMVAVSSVNRTEGNPTFPERKKNSERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWVTDSILAMARPSSELLEKYHIIEQFLSHGIKTIINLQRPGEHASCGNSLEQESGFTYLPEAFMEAGSVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLAPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKYVPKIIHLVCKLLLDLAENRPVVVKSQLEGPGLSAEIEKTVSEMVTMQLDQELLRQNSDAPDPFDPTAVVAEFENQDVSLSNEQDFDPLWKRRDAESLQPLTHLKRQLSYSDSDLKRAKAILEQGETPWTVPAQDLLGHSLQHQAQISNCFIPPTSELGLNKEALVHSTFSFWTQSKCRGLEGLKDNGSPLFCRKDIPKEVQRSRTFSVGISCPHNPGEPVTPNFAGVHMEPEQVTHSHCEAPSGWVPGSVQEDGRTPCSPLNCGSSPKSQCPHVQESQGSSSLLEAMPDDGFQSELSAEARRILAAKALANLKEFVEKEEVKRKVEMWQKELNSREGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRQADAGEALFLLEKGQYQTILCVLHCIVSLQTLPVEVEEACLSHAIKAFTKVSFDSEDGPIVYNTLKKIFKHTLEEKRKMAKDSPRPGLS", "length": 753, "header": "tr|A0A9J7K7I0-1|A0A9J7K7I0_CRIGR Computationally mapped isoform of Protein tyrosine phosphatase domain-containing protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Ptpdc1 PE=4 SV=1 CANONICAL=A0A9J7JJ14-1" }, "locus": {} }, { "isoform_ac": "G3GUH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14/entry#G3GUH5-1", "sequence": { "sequence": "MAAGVLPQNEKTYSTLVNSSGYAANMDENSERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWVTDSILAMARPSSELLEKYHIIEQFLSHGIKTIINLQRPGEHASCGNSLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTAILDMVKVMTFALQEGKVAVHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLAPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKYVPKIIHLVCKLLLDLAENRPVVVKSQLEGPGLSAEIEKTVSEMVTMQLDQELLRQNSDAPDPFDPTAVVAEFENQDVSLSNEQDFDPLWKRRDAESLQPLTHLKRQLSYSDSDLKRAKAILEQGETPWTVPAQDLLGHSLQHQAQISNCFIPPTSELGLNKEALVHSTFSFWTQSKCRGLEGLKDNGSPLFCRKDIPKEVQRSRTFSVGISCPHNPGEPVTPNFAGVHMEPEQVTHSHCEAPSGWVPGSVQEDGRTPCSPLNCGSSPKSQCPHVQESQGSSSLLEAMPDDGFQSELSAEARRILAAKALANLKEFVEKEEVKRKVEMWQKELNSREGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRQADAGEALFLLEKGQYQTILCVLHCIVSLQTLPVEVEEACLSHAIKAFTKVSFDSEDGPIVYNTLKKIFKHTLEEKRKMAKDSPRPGLS", "length": 751, "header": "tr|G3GUH5-1|A0A9J7JJ14_CRIGR Computationally mapped isoform of Protein tyrosine phosphatase domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ptpdc1 PE=3 SV=1 CANONICAL=A0A9J7JJ14-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GUH5", "url": "https://www.uniprot.org/uniprotkb/G3GUH5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GUH5", "url": "https://www.uniprot.org/uniprotkb/G3GUH5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758995", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758995", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1L1R5-1", "protein_name": "Protein tyrosine phosphatase domain-containing protein 1", "gene_name": "ptpdc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAGVSLVSDLPYSTSRESNTDMETVNVRVPTAKYTKVGETLRHVIPGHMQCSMACGGRACKYENPSRWSDKEQAVKGLYSSWITDHLLAMARPSTEIVEKFNIIEQFHVCGLKTVINLQRPGEHASCGSTLEPESGFTYRPELFMEAGIYFYNFGWKDYGVASLTTILDMVKVMSFAMQEGKIAVHCHAGLGRTGVLIACFLVFTSRMSADQAILFVRAKRPNSIQTRGQLLCVREFAQFLVPLRSVFSCAEPKAHEVTLSQYLTRQRHLLHGYEARHMKNMPKIIHLICRLLLDIAENRQTVEEEVLEIPDLTEEVEKTVSLQALQQLGKEMRGKGIPISSPRSPDQPNLLGTPCDPPHDQPLCSDQEFDVLWRWPTVDNTYRSRLILSKCFSYSDSALHKLDPRVHVLQSPQNLSSKSGLNFSELYASQSRLALETPDLLPSDIKSSPKHDLLTGSRSSLVQSKKIEEQVSCPPASVKQAPLKVAKRSMSYGFLGRTNDSSTMFSICQVGRSTNKNSNCDVTQHFKDVPILTLQSELSPETRHLFVAKALTVDLDGEELRSKVSVWQMELNSREGAWERLCNERDPVVLSLLMWSWLEQLKEPVITKDDVETLSGNRLNPEHALNSLDKGQKQTLLCILDCAAHLLKIPEEVENAFFERLIKAFTWISSDSENGQLIYKALKDVMVPVLRDLRTKAMEELEFTCHCSFVP", "length": 713 }, "evidence": [ { "id": "A0A9J7JJ14", "url": "https://omabrowser.org/oma/group/A0A9J7JJ14/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A3K4-1", "protein_name": "Protein tyrosine phosphatase domain-containing protein 1", "gene_name": "PTPDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGVLPQNEQPYSTLVNNSECVANMKGNLERPTPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWVTDNILAMARPSSELLEKYHIIDQFLSHGIKTIINLQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLTPLRNIFSCCDPKAHAVTLPQYLIRQRHLLHGYEARLLKHVPKIIHLVCKLLLDLAENRPVMMKDVSEGPGLSAEIEKTMSEMVTMQLDKELLRHDSDVSNPPNPTAVAADFDNRGMIFSNEQQFDPLWKRRNVECLQPLTHLKRRLSYSDSDLKRAENLLEQGETPQTVPAQILVGHKPRQQKLISHCYIPQSPEPDLHKEALVRSTLSFWSQSKFGGLEGLKDNGSPIFHGRIIPKEAQQSGAFSADVSGSHSPGEPVSPSFANVHKDPNPAHQQVSHCQCKTHGVGSPGSVRQNSRTPRSPLDCGSSPKAQFLVEHETQDSKDLSEAASHSALQSELSAEARRILAAKALANLNESVEKEELKRKVEMWQKELNSRDGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRRADAAEALFLLEKGQHQTILCVLHCIVNLQTIPVDVEEAFLAHAIKAFTKVNFDSENGPTVYNTLKKIFKHTLEEKRKMTKDGPKPGL", "length": 754 }, "evidence": [ { "id": "A0A9J7JJ14", "url": "https://omabrowser.org/oma/group/A0A9J7JJ14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NZK8-1", "protein_name": "Protein tyrosine phosphatase domain-containing protein 1", "gene_name": "Ptpdc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGVLPQNEDPYSTLVNSSGHAAHMDENSGRPAPKYTKVGERLRHVIPGHMACSMACGGRACKYENPARWSEQEQAIKGVYSSWVTDNILAMARPSSELLEKYRIIEQFLGQGIKTIINLQRPGEHASCGSALEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTAILDMVKVMTFALQEGKVAVHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREFTQFLAPLRNIFSCCDPKAHAVTLAQYLIRQRHLLHGYEARLLKYVPKIIHLVCKLLLDLAENRPVVMKSMLEGPVLSAEIEKTVSEMVTLQLDQELLRQNSDVPDPFNPTAEVAEFENQDVILSTEQEFDPLWKRRDIECLQPLTHLKRQLSYSDSDLKRAKAILEQGETPWTVPAQELLDHSLQHQKPTSHCYMPPTPELGFNKEALVQNTFSFWTPSKCGGLEGLKDEGSLLLCRKDIPKEVQRSRTFSVGVSCSHNPGEPVPPNFTSIHKDPEQVTHCRCEAPGGWVPGPVHEMVRSPCSPLNCGSSPKAQFPHGQETQDSTDLSEAVPHAGLQPELSAEARRILAAKALANLNEFVEKEEVKRKVEMWQKELNSREEAWERICGERDPFILCSLMWSWVEQLKEPVITKEDVDMLVDRQADAAEALFLLEKGQYQTILCVLHCIVSLQTLPMEVEEACLLHAIKAFTKVNFDSENGPIVYDTLKKIFKHTLEEKRKMAKDSLS", "length": 747 }, "evidence": [ { "id": "A0A9J7JJ14", "url": "https://omabrowser.org/oma/group/A0A9J7JJ14/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 216, "end_pos": 283, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JJ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ14" }, { "id": "PS50054", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50054" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 301, "start_aa": "Tyr", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 518, "end_pos": 520 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GEQ6-1", "uniprot_ac": "A0A9J7GEQ6", "uniprot_id": "A0A9J7GEQ6_CRIGR", "mass": { "chemical_mass": 84343.0, "monoisotopic_mass": 84343.0 }, "refseq": { "ac": "XP_007644470", "name": "forkhead box protein M1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644470" }, "gene_names": [ { "name": "Foxm1", "type": "recommended", "evidence": [ { "id": "A0A9J7GEQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6" } ] }, { "name": "Foxm1", "type": "synonym", "evidence": [ { "id": "XP_007644470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644470" } ] } ], "protein_names": [ { "name": "Forkhead box protein M1", "type": "recommended", "evidence": [ { "id": "A0A9J7GEQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6/entry#names_and_taxonomy" } ] }, { "name": "forkhead box protein M1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007644470", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644470" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 424 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613610.1) and transcript sequence (IACG01038924.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644470" } ] }, { "annotation": "Transcription factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Also plays a role in DNA break repair, participating in the DNA damage checkpoint response. Promotes transcription of PHB2.", "evidence": [ { "database": "UniProtKB", "id": "G3GUI8", "url": "https://www.uniprot.org/uniprotkb/G3GUI8#function" }, { "database": "UniProtKB", "id": "ARBA00053415", "url": "https://www.uniprot.org/uniprotkb/ARBA00053415#function" }, { "database": "UniProtKB", "id": "A0A9J7GEQ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6#function" }, { "database": "UniProtKB", "id": "A0A9J7GFJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFJ0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEQ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Foxm1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6", "locus": {} } ], "crossref": [ { "id": "cd20029", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20029", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769341", "url": "https://www.ncbi.nlm.nih.gov/gene/100769341", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030456", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030456", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769341", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769341", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GEQ6", "url": "https://www.orthodb.org/?gene=A0A9J7GEQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46878", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46878", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46878:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46878:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644470", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644470", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GEQ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GFJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GFJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3GUI8", "url": "https://www.uniprot.org/uniprotkb/G3GUI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3GUI8-1", "url": "https://www.uniprot.org/uniprotkb/G3GUI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMRTSPRRPLILKRRRLPLPIQNAPGETPEEAKRPPAQQEPTQAQASQEVAESSSCKFPDGIKIINHPTMPNTQVVAIPNNADIQSIITALTAKGKESGSCGPNKFILISSGGTSSHPPGPHPQAQTSHDSKRTEVVTETSGTKPAAKGVPVPKPSGARPRQRQESCAGGEMAGCTLDNSLTNIQWLGKMSSDGLGPCSIKQEMEEKENCHLEQNQVKVEEPSGASTSWQDSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLEPGSPQSPEHLESQQQKRPNPELRKNVTIKSELPLGSRRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIAPKVLLANEGVAPLPAEGPVKEEKPLLEEGLLPLLPIQSIKEEEIQPGEDLAHLERPSRVESPPLEEWPSPCASLKEELSNSWEDSSCSPTPKPKKSSYYGLKSPTRRVSEMLVTKRREKREVSRSRRKQHLRSPCLDEPELLFSEDPGTLRPAMEPLLLAESSEPASQLSCPQEEGGPFKTPVKETLPISSTPSKSALSRTPEAWRLTPPTKVGGLDFSPVRTPQGAFGPLPDSLGLMELNSTPLKSVPLFDSPRELLNSEPFDLASDPFSSSPPPHLEVPKPGSPEPQVPSLSANRSLTEGLVLDTMNDSLSKILLDISFPGLEEDPLGPDNINWSQFIPELR", "length": 765, "header": "tr|A0A9J7GEQ6-1|A0A9J7GEQ6_CRIGR Isoform 1 of Forkhead box protein M1 OS=Cricetulus griseus OX=10029 GN=Foxm1 PE=4 SV=1 CANONICAL=A0A9J7GEQ6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GEQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6/entry#A0A9J7GEQ6-1", "sequence": { "sequence": "MMRTSPRRPLILKRRRLPLPIQNAPGETPEEAKRPPAQQEPTQAQASQEVAESSSCKFPDGIKIINHPTMPNTQVVAIPNNADIQSIITALTAKGKESGSCGPNKFILISSGGTSSHPPGPHPQAQTSHDSKRTEVVTETSGTKPAAKGVPVPKPSGARPRQRQESCAGGEMAGCTLDNSLTNIQWLGKMSSDGLGPCSIKQEMEEKENCHLEQNQVKVEEPSGASTSWQDSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLEPGSPQSPEHLESQQQKRPNPELRKNVTIKSELPLGSRRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIAPKVLLANEGVAPLPAEGPVKEEKPLLEEGLLPLLPIQSIKEEEIQPGEDLAHLERPSRVESPPLEEWPSPCASLKEELSNSWEDSSCSPTPKPKKSSYYGLKSPTRRVSEMLVTKRREKREVSRSRRKQHLRSPCLDEPELLFSEDPGTLRPAMEPLLLAESSEPASQLSCPQEEGGPFKTPVKETLPISSTPSKSALSRTPEAWRLTPPTKVGGLDFSPVRTPQGAFGPLPDSLGLMELNSTPLKSVPLFDSPRELLNSEPFDLASDPFSSSPPPHLEVPKPGSPEPQVPSLSANRSLTEGLVLDTMNDSLSKILLDISFPGLEEDPLGPDNINWSQFIPELR", "length": 765, "header": "tr|A0A9J7GEQ6-1|A0A9J7GEQ6_CRIGR Isoform 1 of Forkhead box protein M1 OS=Cricetulus griseus OX=10029 GN=Foxm1 PE=4 SV=1 CANONICAL=A0A9J7GEQ6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GFJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6/entry#A0A9J7GFJ0-1", "sequence": { "sequence": "MMRTSPRRPLILKRRRLPLPIQNAPGETPEEAKRPPAQQEPTQAQASQEVAESSSCKFPDGIKIINHPTMPNTQVVAIPNNADIQSIITALTAKGKESGSCGPNKFILISSGGTSSHPPGPHPQAQTSHDSKRTEVVTETSGTKPAAKGVPVPKPSGARPRQRQESCAGGEMAGCTLDNSLTNIQWLGKMSSDGLGPCSIKQEMEEKENCHLEQNQVKVEEPSGASTSWQDSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLEPGSPQSPEHLESQQQKRPNPELRKNVTIKSELPLGSRRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIAPKSIKEEEIQPGEDLAHLERPSRVESPPLEEWPSPCASLKEELSNSWEDSSCSPTPKPKKSSYYGLKSPTRRVSEMLVTKRREKREVSRSRRKQHLRSPCLDEPELLFSEDPGTLRPAMEPLLLAESSEPASQLSCPQEEGGPFKTPVKETLPISSTPSKSALSRTPEAWRLTPPTKVGGLDFSPVRTPQGAFGPLPDSLGLMELNSTPLKSVPLFDSPRELLNSEPFDLASDPFSSSPPPHLEVPKPGSPEPQVPSLSANRSLTEGLVLDTMNDSLSKILLDISFPGLEEDPLGPDNINWSQFIPELR", "length": 730, "header": "tr|A0A9J7GFJ0-1|A0A9J7GFJ0_CRIGR Computationally mapped isoform of Forkhead box protein M1 OS=Cricetulus griseus OX=10029 GN=Foxm1 PE=4 SV=1 CANONICAL=A0A9J7GEQ6-1" }, "locus": {} }, { "isoform_ac": "G3GUI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6/entry#G3GUI8-1", "sequence": { "sequence": "MMRTSPRRPLILKRRRLPLPIQNAPGETPEEAKRPPAQQEPTQAQASQEVAESSSCKFPDGIKIINHPTMPNTQVVAIPNNADIQSIITALTAKGKESGSCGPNKFILISSGGTSSHPPGPHPQAQTSHDSKRTEVVTETSGTKPAAKGVPVPKPSGARPRQRQESCAGGEMAGCTLDNSLTNIQWLGKMSSDGLGPCSIKQEMEEKENCHLEQNQVKVEEPSGASTSWQDSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLEPGSPQSPEHLESQQKRPNPELRKNVTIKSELPLGSRRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIAPKVLLANEGVAPLPAEGPVKEEKPLLEEGLLPLLPIQSIKEEEIQPGEDLAHLERPSRVESPPLEEWPSPCASLKEELSNSWEDSSCSPTPKPKKSSYYGLKSPTRRVSEMLVTKRREKREVSRSRRKQHLRSPCLDEPELLFSEDPGTLRPAMEPLLLAESSEPASQLSCPQEEGGPFKTPVKETLPISSTPSKSALSRTPEAWRLTPPTKVGGLDFSPVRTPQGAFGPLPDSLGLMELNSTPLKSVPLFDSPRELLNSEPFDLASDPFSSSPPPHLEVPKPGSPEPQVPSLSANRSLTEGLVLDTMNDSLSKILLDISFPGLEEDPLGPDNINWSQFIPELR", "length": 764, "header": "tr|G3GUI8-1|A0A9J7GEQ6_CRIGR Computationally mapped isoform of Forkhead box protein M1 OS=Cricetulus griseus OX=10029 GN=Foxm1 PE=4 SV=1 CANONICAL=A0A9J7GEQ6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 613, "start_aa": "Thr", "end_pos": 613, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr613", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GUI8", "url": "https://www.uniprot.org/uniprotkb/G3GUI8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3GUI8", "url": "https://www.uniprot.org/uniprotkb/G3GUI8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769341", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769341", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEQ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEQ6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027264500.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264500", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264500" } ] }, { "annotation": "In complex with CRLF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development. Also stimulates B-cells. 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"tr|A0A9J7FR53-1|A0A9J7JK61_CRIGR Computationally mapped isoform of Cardiotrophin-like cytokine factor 1 OS=Cricetulus griseus OX=10029 GN=Clcf1 PE=3 SV=1 CANONICAL=A0A9J7JK61-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JK61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK61/entry#A0A9J7JK61-1", "sequence": { "sequence": "MPKPAGSPSSGCLAGQPVAGGRAGQGVDASERAAAQPKPGARTPPPPPPPLGRSGRGGAGPGAPGPHKGKAPPPPGGVQDREVMVEDVGPANCQLPPLQFSGLSPSSKVRAASPKSPHPCSHLPYYTGLQEASLWETRNLSSPEPRGRKNLPKRKEGRQWKHGSGRLILRERLDRGDSWGMLACLCTVLWHLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETLPRATVNLEVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPAWAPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAASVTLHLEAHGF", "length": 395, "header": "tr|A0A9J7JK61-1|A0A9J7JK61_CRIGR Isoform 1 of Cardiotrophin-like cytokine factor 1 OS=Cricetulus griseus OX=10029 GN=Clcf1 PE=3 SV=1 CANONICAL=A0A9J7JK61-1" }, "locus": {} }, { "isoform_ac": "G3I405-1", "url": 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I405", "url": "https://www.uniprot.org/uniprotkb/G3I405" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"MDLRAGDSWGMLACLCTVLWHLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETLPRATVDLEVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPTWTPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAAVTLHLGAHGF", "length": 225 }, "evidence": [ { "id": "A0A9J7JK61", "url": "https://omabrowser.org/oma/group/A0A9J7JK61/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK61" } ], "pmid": "" }, { "name": "CRLF-CLCF1 complex", "id": "GO:0097058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097058", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK61" } ], "pmid": "" }, { "name": 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"id": "A0A9J7JK61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK61" } ], "pmid": "" }, { "name": "positive regulation of astrocyte differentiation", "id": "GO:0048711", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048711", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK61" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK61" } ], "pmid": "" }, { "name": "positive regulation of isotype switching to IgE isotypes", "id": "GO:0048295", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048295", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JHB1-1", "uniprot_ac": "A0A9J7JHB1", "uniprot_id": "A0A9J7JHB1_CRIGR", "mass": { "chemical_mass": 28119.0, "monoisotopic_mass": 28119.0 }, "refseq": { "ac": "XP_007649112", "name": "nucleolar protein 12 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649112" }, "gene_names": [ { "name": "Nol12", "type": "recommended", "evidence": [ { "id": "A0A9J7JHB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1" } ] }, { "name": "Nol12", "type": "synonym", "evidence": [ { "id": "XP_007649112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649112" } ] } ], "protein_names": [ { "name": "Nucleolar protein 12", "type": "recommended", "evidence": [ { "id": "A0A9J7JHB1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1/entry#names_and_taxonomy" } ] }, { "name": "nucleolar protein 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007649112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649112" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614855.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007649112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649112" } ] }, { "annotation": "Multifunctional RNA binding protein that plays a role in RNA metabolism and DNA maintenance. Participates in the resolution of DNA stress and the maintenance of genome integrity by localizing to sites of DNA insults. Also plays a role in proper nucleolar organization by limiting nucleolar size and regulating nucleolar number. Mechanistically, regulates the nucleolar levels of fibrillarin and nucleolin, two key players in pre-rRNA processing and ribosome assembly.", "evidence": [ { "database": "UniProtKB", "id": "G3I4Z9", "url": "https://www.uniprot.org/uniprotkb/G3I4Z9#function" }, { "database": "UniProtKB", "id": "ARBA00057078", "url": "https://www.uniprot.org/uniprotkb/ARBA00057078#function" }, { "database": "UniProtKB", "id": "A0A9J7JHB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nol12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHB1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHB1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100752251", "url": "https://www.ncbi.nlm.nih.gov/gene/100752251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752251", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHMHSRK", "url": "https://omabrowser.org/oma/group/LHMHSRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JHB1", "url": "https://www.orthodb.org/?gene=A0A9J7JHB1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3I4Z9", "url": "https://www.orthodb.org/?gene=G3I4Z9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14577", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14577", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14577:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14577:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007649112", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649112", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JHB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I4Z9", "url": "https://www.uniprot.org/uniprotkb/G3I4Z9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I4Z9-1", "url": "https://www.uniprot.org/uniprotkb/G3I4Z9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTQGTLPAPPLDVPDQAGWCRPLSTRRFRPAQSCALDHPNPARSMVPAHSQLLVVVDKREYLTGFHKRKVERKKAAIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLPLPEQGDLDGSQEEVSCMEKPTKALPRKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRRAQDSTKKPPSATRTSKTQRRRRMTGKARHSGE", "length": 247, "header": "tr|A0A9J7JHB1-1|A0A9J7JHB1_CRIGR Isoform 1 of Nucleolar protein 12 OS=Cricetulus griseus OX=10029 GN=Nol12 PE=3 SV=1 CANONICAL=A0A9J7JHB1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JHB1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1/entry#A0A9J7JHB1-1", "sequence": { "sequence": "MSTQGTLPAPPLDVPDQAGWCRPLSTRRFRPAQSCALDHPNPARSMVPAHSQLLVVVDKREYLTGFHKRKVERKKAAIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLPLPEQGDLDGSQEEVSCMEKPTKALPRKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRRAQDSTKKPPSATRTSKTQRRRRMTGKARHSGE", "length": 247, "header": "tr|A0A9J7JHB1-1|A0A9J7JHB1_CRIGR Isoform 1 of Nucleolar protein 12 OS=Cricetulus griseus OX=10029 GN=Nol12 PE=3 SV=1 CANONICAL=A0A9J7JHB1-1" }, "locus": {} }, { "isoform_ac": "G3I4Z9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1/entry#G3I4Z9-1", "sequence": { "sequence": "MGRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLPLPEQGDLDGSQEEVSCMEKPTKALPRKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRRAQDSTKKPPSATRTSKTQRRRRMTGKARHSGE", "length": 215, "header": "tr|G3I4Z9-1|A0A9J7JHB1_CRIGR Computationally mapped isoform of Nucleolar protein 12 OS=Cricetulus griseus OX=10029 GN=Nol12 PE=3 SV=1 CANONICAL=A0A9J7JHB1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I4Z9", "url": "https://www.uniprot.org/uniprotkb/G3I4Z9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I4Z9", "url": "https://www.uniprot.org/uniprotkb/G3I4Z9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752251", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752251", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LFR6-1", "protein_name": "Nucleolar protein 12", "gene_name": "NOL12", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRNKKKKRDGDSRRPRLILSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQKKLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEQGAGHGPEEETSSVEKPSRALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRAQESTKKPPSATRTSKTQRRRLTGKARHSGE", "length": 214 }, "evidence": [ { "id": "A0A9J7JHB1", "url": "https://omabrowser.org/oma/group/A0A9J7JHB1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2KIV0-1", "protein_name": "Nucleolar protein 12", "gene_name": "NOL12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGRNKKKRDGDDRRQRLILSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQKKLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLPTPEQGAGSGPEEEVSSMEKPTRALPRKSRDPLLSQRISSLTASLHAHSRKKVKKKRLRRAQDTTKKPPSATRTSKTRRRRLTGKARHSGE", "length": 213 }, "evidence": [ { "id": "A0A9J7JHB1", "url": "https://omabrowser.org/oma/group/A0A9J7JHB1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5D1Z3-1", "protein_name": "Nucleolar protein 12", "gene_name": "Nol12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRNKKKKRDGDDRRPRLILNFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPNHTVTVTTVSDLDLSGARLLGLPLPEQGDQDGSQEEEVSSMEKPTKALPKKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRRAQDSTKKPPSATRTSKTQRRRRMTGKARHNGE", "length": 216 }, "evidence": [ { "id": "A0A9J7JHB1", "url": "https://omabrowser.org/oma/group/A0A9J7JHB1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7ZWE7-1", "protein_name": "Nucleolar protein 12", "gene_name": "nol12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKSDRLQQGSKGKGGGKRKHGKCVLMFDDKDRQDFLTGFHKRKLERRRAALEEMKSKLKEEQKRLREERHKEYLKMLQERRQALDEADELEEAITATTECVQYDHPNHTVTVTTISDLDLSADRLLEPAQRDGGDGEERERTEALPKQAGNPLLSKKIQSLTASLNSLVKQKKRRKQKRRQEAKQRSHQSDRKSSSSAFVHNNKQKQGKSTKRQRRRQTGRNERSQD", "length": 228 }, "evidence": [ { "id": "A0A9J7JHB1", "url": "https://omabrowser.org/oma/group/A0A9J7JHB1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BG17-1", "protein_name": "Nucleolar protein 12", "gene_name": "Nol12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRNKKKKKRDGDDRRPRLVLNFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKQEQKKLREERHQEYLKMLAEREEALEEADELERLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLPLPEQGDQDGSQEEEMSSLEKPTKALPRKSKDPLLSQRISSLTATLHAHSRKKVKRKHPRRAQDSTKKPPSATRTSKTQRRRRMTGKARHNGE", "length": 217 }, "evidence": [ { "id": "A0A9J7JHB1", "url": "https://omabrowser.org/oma/group/A0A9J7JHB1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UGY1-1", "protein_name": "Nucleolar protein 12", "gene_name": "NOL12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRAQDSKKPPRAPRTSKAQRRRLTGKARHSGE", "length": 213 }, "evidence": [ { "id": "A0A9J7JHB1", "url": "https://omabrowser.org/oma/group/A0A9J7JHB1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1" } ], "pmid": "" }, { "name": "rRNA binding", "id": "GO:0019843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019843", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHB1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHB1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"mass": { "chemical_mass": 24230.0, "monoisotopic_mass": 24230.0 }, "refseq": { "ac": "XP_016835951", "name": "probable glutathione peroxidase 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835951" }, "gene_names": [ { "name": "Gpx8", "type": "recommended", "evidence": [ { "id": "A0A9J7JGT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2" } ] }, { "name": "Gpx8", "type": "synonym", "evidence": [ { "id": "XP_016835951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835951" } ] } ], "protein_names": [ { "name": "Glutathione peroxidase", "type": "recommended", "evidence": [ { "id": "A0A9J7JGT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2/entry#names_and_taxonomy" } ] }, { "name": "probable glutathione peroxidase 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016835951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835951" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615347.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016835951", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835951" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gpx8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2", "locus": {} } ], "crossref": [ { "id": "A0A9J7JGT2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JGT2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100775000", "url": "https://www.ncbi.nlm.nih.gov/gene/100775000", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100775000", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775000", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTWNFCK", "url": "https://omabrowser.org/oma/group/PTWNFCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FGW2", "url": "https://www.orthodb.org/?gene=A0A9J7FGW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JGT2", "url": "https://www.orthodb.org/?gene=A0A9J7JGT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3IAX4", "url": "https://www.orthodb.org/?gene=G3IAX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11592:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11592:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00255", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00255", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016835951", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835951", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16833", "url": "https://www.rhea-db.org/rhea/16833", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FGW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FGW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3IAX4", "url": "https://www.uniprot.org/uniprotkb/G3IAX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3IAX4-1", "url": "https://www.uniprot.org/uniprotkb/G3IAX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPFAAYPLKCSGSKAKVFAVLLSMVLCTVMLFLLQLKFLKPRINSFYSFEVKDAKGKIVSLEKFKGKEASLVVNVASDCRYTDKSYLTLKELHKEFGPYHFNVLAFPCNQFGESEPRSSTEVESFARRNYGVTFPIFHKIKILGPEAEPAFRFLVDSSKKEPMWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMVGQMILKKKEDL", "length": 210, "header": "tr|A0A9J7JGT2-1|A0A9J7JGT2_CRIGR Isoform 1 of Glutathione peroxidase OS=Cricetulus griseus OX=10029 GN=Gpx8 PE=3 SV=1 CANONICAL=A0A9J7JGT2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FGW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2/entry#A0A9J7FGW2-1", "sequence": { "sequence": "MEPFAAYPLKCSGSKAKVFAVLLSMVLCTVMLFLLQLKFLKPRINSFYSFEVKDAKGKIVSLEKFKGKILPRRNQCGTFGSIWSTLRDKL", "length": 90, "header": "tr|A0A9J7FGW2-1|A0A9J7FGW2_CRIGR Computationally mapped isoform of Probable glutathione peroxidase 8 isoform X3 OS=Cricetulus griseus OX=10029 GN=Gpx8 PE=4 SV=1 CANONICAL=A0A9J7JGT2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JGT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2/entry#A0A9J7JGT2-1", "sequence": { "sequence": "MEPFAAYPLKCSGSKAKVFAVLLSMVLCTVMLFLLQLKFLKPRINSFYSFEVKDAKGKIVSLEKFKGKEASLVVNVASDCRYTDKSYLTLKELHKEFGPYHFNVLAFPCNQFGESEPRSSTEVESFARRNYGVTFPIFHKIKILGPEAEPAFRFLVDSSKKEPMWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMVGQMILKKKEDL", "length": 210, "header": "tr|A0A9J7JGT2-1|A0A9J7JGT2_CRIGR Isoform 1 of Glutathione peroxidase OS=Cricetulus griseus OX=10029 GN=Gpx8 PE=3 SV=1 CANONICAL=A0A9J7JGT2-1" }, "locus": {} }, { "isoform_ac": "G3IAX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2/entry#G3IAX4-1", "sequence": { "sequence": "MEPFAAYPLKCSGSKAKVFAVLLSMVLCTVMLFLLQLKFLKPRINSFYSFEVKDAKGKIVSLEKFKGKASLVVNVASDCRYTDKSYLTLKELHKEFGPYHFNVLAFPCNQFGESEPRSSTEVESFARRNYGVTFPIFHKIKILGPEAEPAFRFLVDSSKKEPMWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMVGQMILKKKEDL", "length": 209, "header": "tr|G3IAX4-1|A0A9J7JGT2_CRIGR Computationally mapped isoform of Glutathione peroxidase OS=Cricetulus griseus OX=10029 GN=Gpx8 PE=3 SV=1 CANONICAL=A0A9J7JGT2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3IAX4", "url": "https://www.uniprot.org/uniprotkb/G3IAX4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3IAX4", "url": "https://www.uniprot.org/uniprotkb/G3IAX4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100775000", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775000", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZPW7-1", "protein_name": "Glutathione peroxidase", "gene_name": "Gpx8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPLGAYPLKCSGPKAKIFAVLLSMVLCTVMLFLLQLKFLKPRINSFYSFEVKDAKGRMVSLEKFKGKASLVVNVASDCRFTDKSYETLRELHKEFGPYHFNVLAFPCNQFGESEPKSSKEVESFARKNYGVTFPIFHKIKILGPEAEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMIGQIILKKKEDL", "length": 209 }, "evidence": [ { "id": "A0A9J7JGT2", "url": "https://omabrowser.org/oma/group/A0A9J7JGT2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36014-1", "protein_name": "Glutathione peroxidase-like peroxiredoxin 1", "gene_name": "GPX1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQEFYSFSPIDENGNPFPFNSLRNKVVLIVNVASHCAFTPQYKELEYLYEKYKSHGLVIVAFPCGQFGNQEFEKDKEINKFCQDKYGVTFPILHKIRCNGQKQDPVYKFLKNSVSGKSGIKMIKWNFEKFVVDRNGKVVKRFSCMTRPLELCPIIEELLNQPPEEQI", "length": 167 }, "evidence": [ { "id": "A0A9J7JGT2", "url": "https://omabrowser.org/oma/group/A0A9J7JGT2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q2NL01-1", "protein_name": "Protein peroxidase GPX8", "gene_name": "GPX8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPLTAYPLRCSGPKAKAFAVLLSMVLCTVMLFLLQLKFLKPKINSFYTFEVKDANGRVVSLEKFKGKVALVVNVASDCQLTDRNYLALQELHKEFGPFHFSVLAFPCNQFGESEPRPSKEVVSFARNNFGVTFPIFHKIKILGSEAEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKTWRPEEPIEVIRPEIAALIRQMIIKKKEDL", "length": 209 }, "evidence": [ { "id": "A0A9J7JGT2", "url": "https://omabrowser.org/oma/group/A0A9J7JGT2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8L910-1", "protein_name": "Probable glutathione peroxidase 4", "gene_name": "GPX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGASASVPERSVHQFTVKDSSGKDLNMSIYQGKVLLIVNVASKCGFTETNYTQLTELYRKYKDQDFEILAFPCNQFLYQEPGTSQEAHEFACERFKAEYPVFQKVRVNGQNAAPIYKFLKASKPTFLGSRIKWNFTKFLVGKDGLVIDRYGTMVTPLSIEKDIKKALEDA", "length": 170 }, "evidence": [ { "id": "A0A9J7JGT2", "url": "https://omabrowser.org/oma/group/A0A9J7JGT2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8TED1-1", "protein_name": "Protein peroxidase GPX8", "gene_name": "GPX8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKFWKPEEPIEVIRPDIAALVRQVIIKKKEDL", "length": 209 }, "evidence": [ { "id": "A0A9J7JGT2", "url": "https://omabrowser.org/oma/group/A0A9J7JGT2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7B7-1", "protein_name": "Protein peroxidase GPX8", "gene_name": "Gpx8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPFAAYPLKCSGPKAKIFAVLLSMVLCTVMLFLLQLKFLKPRTNSFYSFEVKDAKGRTVSLEKFKGKASLVVNVASDCRFTDKSYQTLRELHKEFGPYHFNVLAFPCNQFGESEPKSSKEVESFARQNYGVTFPIFHKIKILGPEAEPAFRFIVDSSKKEPRWNFWKYLVNPEGQVVKFWRPEEPLEAIRPHVSQMIGQIILKKKEDL", "length": 209 }, "evidence": [ { "id": "A0A9J7JGT2", "url": "https://omabrowser.org/oma/group/A0A9J7JGT2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "R4GGB2-1", "protein_name": "Glutathione peroxidase", "gene_name": "GPX8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPLTAAYPLKYSVPKARVFVVFLSMVFCTAVLCLLQLRFFKPKTKDFYSFEIKDSRGRIVSLEKYRGKATLVVNVASYCQHTDKNYIALQDLHREFGPSHFTVLAFPCNQFGESEPGSSQEIEAFAKGNYGVTFPVFHKIKILGSEAEPAFKFLIDSSKKEPRWNFWKYLVSPEGKVVKFWRPEEPIESIKPEIASLIRQIIMKKREDL", "length": 210 }, "evidence": [ { "id": "A0A9J7JGT2", "url": "https://omabrowser.org/oma/group/A0A9J7JGT2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "glutathione peroxidase activity", "id": "GO:0004602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004602", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2" } ], "pmid": "" }, { "name": "peroxidase activity", "id": "GO:0004601", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004601", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGT2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16833", "name": "", "equation": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7HAH3-1" ], "evidence": [ { "id": "16833", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16833" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7HAH3", "gene_name": "Cp", "activity": [ { "ec_number": "1.11.1.27", "activity": "a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O.", "evidence": [ { "id": "A0A9J7HAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAH3" } ] }, { "ec_number": "1.16.3.1", "activity": "4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O.", "evidence": [ { "id": "A0A9J7HAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAH3" } ] }, { "ec_number": "1.11.1.9", "activity": "2 glutathione + H2O2 = glutathione disulfide + 2 H2O.", "evidence": [ { "id": "A0A9J7HAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAH3" } ] }, { "ec_number": "1.16.3.4", "activity": "4 Cu(+) + O2 + 4 H(+) = 4 Cu(2+) + 2 H2O.", "evidence": [ { "id": "A0A9J7HAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAH3" } ] }, { "ec_number": "1.16.3.1", "activity": "", "evidence": [ { "id": "A0A9J7HAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAH3" } ] }, { "ec_number": "1.11.1.27", "activity": "", "evidence": [ { "id": "A0A9J7HAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAH3" } ] }, { "ec_number": "1.16.3.4", "activity": "", 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"mass": { "chemical_mass": 21530.0, "monoisotopic_mass": 21530.0 }, "refseq": { "ac": "XP_007645267", "name": "gem-associated protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645267" }, "gene_names": [ { "name": "Gemin6", "type": "recommended", "evidence": [ { "id": "A0A9J7GCC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8" } ] }, { "name": "Gemin6", "type": "synonym", "evidence": [ { "id": "XP_007645267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645267" } ] } ], "protein_names": [ { "name": "Gem-associated protein 6", "type": "recommended", "evidence": [ { "id": "A0A9J7GCC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8/entry#names_and_taxonomy" } ] }, { "name": "gem-associated protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007645267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645267" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614257.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645267", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645267" } ] }, { "annotation": "The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP.", "evidence": [ { "database": "UniProtKB", "id": "G3HSZ2", "url": "https://www.uniprot.org/uniprotkb/G3HSZ2#function" }, { "database": "UniProtKB", "id": "ARBA00059373", "url": "https://www.uniprot.org/uniprotkb/ARBA00059373#function" }, { "database": "UniProtKB", "id": "A0A9J7GCC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8#function" }, { "database": "UniProtKB", "id": "A0A9J7JP50", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP50#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gemin6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCC8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCC8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11676", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11676", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756163", "url": "https://www.ncbi.nlm.nih.gov/gene/100756163", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046856", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046856", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756163", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756163", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LEWEDYV", "url": "https://omabrowser.org/oma/group/LEWEDYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GCC8", "url": "https://www.orthodb.org/?gene=A0A9J7GCC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JP50", "url": "https://www.orthodb.org/?gene=A0A9J7JP50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HSZ2", "url": "https://www.orthodb.org/?gene=G3HSZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14710", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14710", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14710:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14710:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20417", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20417", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645267", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645267", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP50", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HSZ2", "url": "https://www.uniprot.org/uniprotkb/G3HSZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HSZ2-1", "url": "https://www.uniprot.org/uniprotkb/G3HSZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDMPREFQNPPEAICFRSSQLVTMSEWMKKSPLEWEDYVYKEVRVIASEKKEYQGWLLTTDPVSANIVLVNFLEDGSLSVTGIMGHCVQTVETLSEGDHRVREKLMHLFTSGDCKGYSPEDLEKRKNSLKKWLEKNHIPVTEQGDAQRTLCVAGVLTIDPPYAPENCSSSNEIILSRVQDLIQGHLSASQ", "length": 190, "header": "tr|A0A9J7GCC8-1|A0A9J7GCC8_CRIGR Isoform 1 of Gem-associated protein 6 OS=Cricetulus griseus OX=10029 GN=Gemin6 PE=4 SV=1 CANONICAL=A0A9J7GCC8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8/entry#A0A9J7GCC8-1", "sequence": { "sequence": "MDMPREFQNPPEAICFRSSQLVTMSEWMKKSPLEWEDYVYKEVRVIASEKKEYQGWLLTTDPVSANIVLVNFLEDGSLSVTGIMGHCVQTVETLSEGDHRVREKLMHLFTSGDCKGYSPEDLEKRKNSLKKWLEKNHIPVTEQGDAQRTLCVAGVLTIDPPYAPENCSSSNEIILSRVQDLIQGHLSASQ", "length": 190, "header": "tr|A0A9J7GCC8-1|A0A9J7GCC8_CRIGR Isoform 1 of Gem-associated protein 6 OS=Cricetulus griseus OX=10029 GN=Gemin6 PE=4 SV=1 CANONICAL=A0A9J7GCC8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JP50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8/entry#A0A9J7JP50-1", "sequence": { "sequence": "MLVSGGPPQGSFRSSQLVTMSEWMKKSPLEWEDYVYKEVRVIASEKKEYQGWLLTTDPVSANIVLVNFLEDGSLSVTGIMGHCVQTVETLSEGDHRVREKLMHLFTSGDCKGYSPEDLEKRKNSLKKWLEKNHIPVTEQGDAQRTLCVAGVLTIDPPYAPENCSSSNEIILSRVQDLIQGHLSASQ", "length": 186, "header": "tr|A0A9J7JP50-1|A0A9J7JP50_CRIGR Computationally mapped isoform of Gem-associated protein 6 OS=Cricetulus griseus OX=10029 GN=Gemin6 PE=4 SV=1 CANONICAL=A0A9J7GCC8-1" }, "locus": {} }, { "isoform_ac": "G3HSZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8/entry#G3HSZ2-1", "sequence": { "sequence": "MSEWMKKSPLEWEDYVYKEVRVIASEKKEYQGWLLTTDPVSANIVLVNFLEDGSLSVTGIMGHCVQTVETLSEGDHRVREKLMHLFTSGDCKGYSPEDLEKRKNSLKKWLEKNHIPVTEQGDAQRTLCVAGVLTIDPPYAPENCSSSNEIILSRVQDLIQGHLSASQ", "length": 167, "header": "tr|G3HSZ2-1|A0A9J7GCC8_CRIGR Computationally mapped isoform of Gem-associated protein 6 OS=Cricetulus griseus OX=10029 GN=Gemin6 PE=4 SV=1 CANONICAL=A0A9J7GCC8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HSZ2", "url": "https://www.uniprot.org/uniprotkb/G3HSZ2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HSZ2", "url": "https://www.uniprot.org/uniprotkb/G3HSZ2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756163", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756163", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V972-1", "protein_name": "Gem-associated protein 6", "gene_name": "Gemin6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEWTKKSPLEWEDYVYKEVRVIASEKEYKGWLLTTDPVSANIVLVNFLEDGRLCVTGIMGHSVQTVETVSEGDHRVREKLMHLFTSADCKGYSPEDLEKKKTSLKKWLEKNHIPVTEEGDTQRTLCVAGVLTIDPPYAPENCSSSNEIILSRIQDLIQGHLSASQ", "length": 166 }, "evidence": [ { "id": "A0A9J7GCC8", "url": "https://omabrowser.org/oma/group/A0A9J7GCC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2KHW8-1", "protein_name": "Gem-associated protein 6", "gene_name": "GEMIN6", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNEWMKKGPLEWQDYTYKAVSVTASDKEYKGWVLTTDPVSANIVLVNFLEDGSMSVTGIMGHAVQTVEIVNEGDHSVREKLMHLFMSGDCKAYSPEDLEKRKNSLKKWLEKNHIPITEQRDSRKTLCVAGVLTIDPPYGPENCNSSNEIILSRVQDLIQGHLEASQ", "length": 166 }, "evidence": [ { "id": "A0A9J7GCC8", "url": "https://omabrowser.org/oma/group/A0A9J7GCC8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8WXD5-1", "protein_name": "Gem-associated protein 6", "gene_name": "GEMIN6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEWMKKGPLEWQDYIYKEVRVTASEKNEYKGWVLTTDPVSANIVLVNFLEDGSMSVTGIMGHAVQTVETMNEGDHRVREKLMHLFTSGDCKAYSPEDLEERKNSLKKWLEKNHIPITEQGDAPRTLCVAGVLTIDPPYGPENCSSSNEIILSRVQDLIEGHLTASQ", "length": 167 }, "evidence": [ { "id": "A0A9J7GCC8", "url": "https://omabrowser.org/oma/group/A0A9J7GCC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CX53-1", "protein_name": "Gem-associated protein 6", "gene_name": "Gemin6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEWMKKSPLEWEDYVYKEVRVIACEKEYKGWLLTTDPVSANIVLVNFLEDGRLSVTGIMGHSVQTVETISEGDHRVREKLMHVFASGDCKGYSPEDLEEKRTSLKKWLEKNHIPVTEQGDAQRTLCVAGVLTIDPPYAPENCSSSNEIILSRIQDLIQGHLSASQ", "length": 166 }, "evidence": [ { "id": "A0A9J7GCC8", "url": "https://omabrowser.org/oma/group/A0A9J7GCC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8" } ], "pmid": "" }, { "name": "SMN complex", "id": "GO:0032797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032797", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8" } ], "pmid": "" }, { "name": "Gemini of Cajal bodies", "id": "GO:0097504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097504", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "spliceosomal snRNP assembly", "id": "GO:0000387", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000387", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8" } ], "pmid": "" }, { "name": "spliceosomal complex assembly", "id": "GO:0000245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000245", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GCC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCC8" }, { "id": "PS52001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AD", "eco_id": "ECO_0000259", "start_pos": 92, "end_pos": 190, "start_aa": "Glu", 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"yes" } }, { "uniprot_canonical_ac": "A0A9J7GBR3-1", "uniprot_ac": "A0A9J7GBR3", "uniprot_id": "A0A9J7GBR3_CRIGR", "mass": { "chemical_mass": 109372.0, "monoisotopic_mass": 109372.0 }, "refseq": { "ac": "XP_016830272", "name": "unconventional myosin-XIX isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830272" }, "gene_names": [ { "name": "Myo19", "type": "recommended", "evidence": [ { "id": "A0A9J7GBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ] }, { "name": "Myo19", "type": "synonym", "evidence": [ { "id": "XP_016830272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830272" } ] } ], "protein_names": [ { "name": "Unconventional myosin-XIX", "type": "recommended", "evidence": [ { "id": "A0A9J7GBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3/entry#names_and_taxonomy" } ] }, { "name": "unconventional myosin-XIX isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016830272", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830272" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016830272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830272" } ] }, { "annotation": "Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane. Motor protein that moves towards the plus-end of actin filaments. Required for mitochondrial inheritance during mitosis. May be involved in mitochondrial transport or positioning.", "evidence": [ { "database": "UniProtKB", "id": "G3H9D9", "url": "https://www.uniprot.org/uniprotkb/G3H9D9#function" }, { "database": "UniProtKB", "id": "ARBA00054433", "url": "https://www.uniprot.org/uniprotkb/ARBA00054433#function" }, { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3#function" }, { "database": "UniProtKB", "id": "A0A9J7JYI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYI1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Myo19", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3", "locus": {} } ], "crossref": [ { "id": "cd14880", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14880", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759803", "url": "https://www.ncbi.nlm.nih.gov/gene/100759803", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001609", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001609", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036961", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016830272", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016830272", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H9D9", "url": "https://www.uniprot.org/uniprotkb/G3H9D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3H9D9-1", "url": "https://www.uniprot.org/uniprotkb/G3H9D9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQQVNGHSSGTDAEGKASLKGDLQQFLDGEAPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKPIPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIKPINQSIVVSGESGAGKTWTSRCLMKFYAVVASSSASCENHKMAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASNERNFHIFYQICKGATKDERLQWYLPEGAAFSWLPNPENNLEEDCFELTREAMLHLGIDTPTQNNIFKDFKPHRTISKELAITVLAGLLHLGNVHFTDSEDEAQPCQLMDGTKVSVRTSASLLHLQEDLLLETMQIRTIKAGKQQQVFRKPCSRAECDTRRDCLAKLIYARLFNWLVSVINSSICADSSSWTAFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLKAQQEEYAVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQSRIESALAGKPCLGHNKLSREPSFVVVHFAGPVRYHTEGLVEKNKDPVPPELTGLLQQSQDPLLMMLFPDNPEEKTQEELSGQSRVPALTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQSKPQTFLQKEVLSQLEACGLVETIHISAAGFPIRVSHQNFVERYKLLRRLRPRTSSGLQGLCPARGPSEQPLCAKDATLQPPLQDILHALPALIQTATTPSDPAETTQVPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHQLQKQKKQRQAAVLIQAAIRSWLTRKHIQRLHIAATVIKRAWHKWRIRMACLAAKELDGMEEKPMTQTPSSLSSSLPPAHTNLLGAIIHLWPLGLVLANSAVGVRGFQRKLVAYACLRLPSSSPSNNIQTAQDQAGITSIRALPQGSIKFHCRKSPLQYADICPEPSASSVSGFNQILLERNRPVQV", "length": 977, "header": "tr|A0A9J7GBR3-1|A0A9J7GBR3_CRIGR Isoform 1 of Unconventional myosin-XIX OS=Cricetulus griseus OX=10029 GN=Myo19 PE=3 SV=1 CANONICAL=A0A9J7GBR3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3/entry#A0A9J7GBR3-1", "sequence": { "sequence": "MLQQVNGHSSGTDAEGKASLKGDLQQFLDGEAPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKPIPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIKPINQSIVVSGESGAGKTWTSRCLMKFYAVVASSSASCENHKMAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASNERNFHIFYQICKGATKDERLQWYLPEGAAFSWLPNPENNLEEDCFELTREAMLHLGIDTPTQNNIFKDFKPHRTISKELAITVLAGLLHLGNVHFTDSEDEAQPCQLMDGTKVSVRTSASLLHLQEDLLLETMQIRTIKAGKQQQVFRKPCSRAECDTRRDCLAKLIYARLFNWLVSVINSSICADSSSWTAFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLKAQQEEYAVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQSRIESALAGKPCLGHNKLSREPSFVVVHFAGPVRYHTEGLVEKNKDPVPPELTGLLQQSQDPLLMMLFPDNPEEKTQEELSGQSRVPALTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQSKPQTFLQKEVLSQLEACGLVETIHISAAGFPIRVSHQNFVERYKLLRRLRPRTSSGLQGLCPARGPSEQPLCAKDATLQPPLQDILHALPALIQTATTPSDPAETTQVPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHQLQKQKKQRQAAVLIQAAIRSWLTRKHIQRLHIAATVIKRAWHKWRIRMACLAAKELDGMEEKPMTQTPSSLSSSLPPAHTNLLGAIIHLWPLGLVLANSAVGVRGFQRKLVAYACLRLPSSSPSNNIQTAQDQAGITSIRALPQGSIKFHCRKSPLQYADICPEPSASSVSGFNQILLERNRPVQV", "length": 977, "header": "tr|A0A9J7GBR3-1|A0A9J7GBR3_CRIGR Isoform 1 of Unconventional myosin-XIX OS=Cricetulus griseus OX=10029 GN=Myo19 PE=3 SV=1 CANONICAL=A0A9J7GBR3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3/entry#A0A9J7JYI1-1", "sequence": { "sequence": "MRGTSTSSTRFAKEPPRMKGSSGTSLRELPSPGYPIQKTTWKVLAGLLHLGNVHFTDSEDEAQPCQLMDGTKVSVRTSASLLHLQEDLLLETMQIRTIKAGKQQQVFRKPCSRAECDTRRDCLAKLIYARLFNWLVSVINSSICADSSSWTAFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLKAQQEEYAVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQSRIESALAGKPCLGHNKLSREPSFVVVHFAGPVRYHTEGLVEKNKDPVPPELTGLLQQSQDPLLMMLFPDNPEEKTQEELSGQSRVPALTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQSKPQTFLQKEVLSQLEACGLVETIHISAAGFPIRVSHQNFVERYKLLRRLRPRTSSGLQGLCPARGPSEQPLCAKDATLQPPLQDILHALPALIQTATTPSDPAETTQVPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHQLQKQKKQRQAAVLIQAAIRSWLTRKHIQRLHIAATVIKRAWHKWRIRMACLAAKELDGMEEKPMTQTPSSLSSSLPPAHTNLLGAIIHLWPLGLVLANSAVGVRGFQRKLVAYACLRLPSSSPSNNIQTAQDQAGITSIRALPQGSIKFHCRKSPLQYADICPEPSASSVSGFNQILLERNRPVQV", "length": 706, "header": "tr|A0A9J7JYI1-1|A0A9J7JYI1_CRIGR Computationally mapped isoform of Unconventional myosin-XIX OS=Cricetulus griseus OX=10029 GN=Myo19 PE=3 SV=1 CANONICAL=A0A9J7GBR3-1" }, "locus": {} }, { "isoform_ac": "G3H9D9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3/entry#G3H9D9-1", "sequence": { "sequence": "MLQQVNGHSSGTDAEGKASLKGDLQQFLDGEAPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKPIPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIKPINQSIVVSGESGAGKTWTSRCLMKFYAVVASSSASCENHKMAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASNERNFHIFYQICKGATKDERLQWYLPEGAAFSWLPNPENNLEEDCFELTREAMLHLGIDTPTQNNIFKVLAGLLHLGNVHFTDSEDEAQPCQLMDGTKVSVRTSASLLHLQEDLLLETMQIRTIKAGKQQQVFRKPCSRAECDTRRDCLAKLIYARLFNWLVSVINSSICADSSSWTAFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLKAQQEEYAVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQSRIESALAGKPCLGHNKLSREPSFVVVHFAGPVRYHTEGLVEKNKDPVPPELTGLLQQSQDPLLMMLFPDNPEEKTQEELSGQSRVPALTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQSKPQTFLQKEVLSQLEACGLVETIHISAAGFPIRVSHQNFVERYKLLRRLRPRTSSGLQGLCPARGPSEQPLCAKDATLQPPLQDILHALPALIQTATTPSDPAETTQVPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHQLQKQKKQRQAAVLIQAAIRSWLTRKHIQRLHIAATVIKRAWHKWRIRMACLAAKELDGMEEKPMTQTPSSLSSSLPPAHTNLLGAIIHLWPLGLVLANSAVGVRGFQRKLVAYACLRLPSSSPSNNIQTAQDQAGITSIRALPQGSIKFHCRKSPLQYADICPEPSASSVSGFNQILLERNRPVQV", "length": 962, "header": "tr|G3H9D9-1|A0A9J7GBR3_CRIGR Computationally mapped isoform of Unconventional myosin-XIX OS=Cricetulus griseus OX=10029 GN=Myo19 PE=3 SV=1 CANONICAL=A0A9J7GBR3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H9D9", "url": "https://www.uniprot.org/uniprotkb/G3H9D9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3H9D9", "url": "https://www.uniprot.org/uniprotkb/G3H9D9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759803", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759803", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AME4-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "MYO19", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPKQVNCQKEDSVTQNDMNESFEEEVRAFLSDEEQLHLFDDLTKVNPVTTTTVLKCLQARYTVNLFYTNAGCSLVALNPFQPISCLYSPELMREYHVAVRPQDLKPHIFAVAEQTYRNVQSQINPINQSIIVSGESGAGKTWTSRCLMKFYASVAASATSPKGNEAVERIEKRVLDSNPIMEAFGNACTLRNNNSSRFGKYIQLHLDRFHHLSSASIQTFLLEKTRVAYQAPNERNFHIFYQITKGATAEERLAWNLPEGAHYRWLPNSERNLEEDCFEVTRDAMFHLGIDHSTQNNIFKVLSGLLHLGNIQFSNPVDESQPCELEDKAKDFVKTAGDLLKIPVEELLQSLRIRTITAGKQQQVVKKPCSRTECDTRRDCLAKVIYAKLFDWLVLVINESIYADTSLWTSFIGLLDVYGFEAFPENNLEQLCINYANEKLQQHFVAHYLKAQQEEYASEGLQWSFINYQDNQSCLDLIEGNPLSIFSLLNEECRLNRSSNPDLFQTRIEKALSDNQCLSRDKFSKKPNFIISHYAGKVCYQLAAMVEKNKDPIPPELVHVLQNSKDTLLQKLFPIAETNQNNTKTQNRAAVVTVVSKFKSSLENLMQILNSTEPHYIRCIKPNADCQAMTFRKEEVLSQLQACGIVEAITISAAGFPIRISFQSFTDRYEILRKSRRSSKNNACDKSNYHTAKKKGETAAVDDNKASHSVIAEILQNVVTGQSAAEPTGKGSESTSVYCGKTKVFMANSVLEQLEARRAEVLNKKAFCIQCFWRRFKQKKLAKERRCATLIQAAIRSWLAKNRFQRMRRAADVIKRGWRKWKAKMAALAAAELDENDEKTPFSAMSAKSPCSLETAWPLSAIIQFWPLGLVLSAAPVTIVGLRRELSLLACLKVLQGIGCYKMESSFLGCGITSVRALPQGSVRFHCKKSPLHYANVSPHTAAYSTTGFNQILLDRKELLPT", "length": 962 }, "evidence": [ { "id": "A0A9J7GBR3", "url": "https://omabrowser.org/oma/group/A0A9J7GBR3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3Z8I9-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "Myo19", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHQQVNGHSLGSDTQGRTSLKGDLREFLGGEVPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKHIPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIEPINQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSCENHKMAERIEERILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQAASERNFHIFYQICKGATKEERLQWCLPEGTAFSWLPNPESSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNVHFVDSEDEAQPCQLMDGTKGSVRTSALLLQLPDNMLLESMQIRTIKAGKQQQVFQKPCSRAECDTRRDCLAKLIYARLFDWLVSVINSSICADFSSWTAFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLRAQQEEYEVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQTRIESTLAGRPCLGHNKLSREPSFVVMHFAGPVRYCTAGLVEKNKDPVPPELTGLLQQSQDPLLMMLFPANPEEKTQEELSGQSRAPALTVVSKFKASLEQLLQVLHKTTPHYIRCIKPNSQSQPQTFLQEEVLNQLEACGLVETIHISAAGFPIRVSHQNFMERYKLLTRLRPRTSSGLRSLCPAKGSSEQPLCAKEATLQPLLQDILHALPALIQTATTPSDPAKTAQIPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHRLQKQEKQRRAAVIIQAAFRSWLTRKHIRRLHIAATVIKHAWHKWRIRMACLASKELDGMEEKLMPQAPGTLRSSLSPAHTRFLGAIIHLWPLGLVLANSADGMRGFQRKLVAHACLRLPASGPSNKVQTPQQDQAGITSIRALPQGSIKFHCRKSPLQYADICPDPSASNVTGFNQILLLERHRPVQV", "length": 964 }, "evidence": [ { "id": "A0A9J7GBR3", "url": "https://omabrowser.org/oma/group/A0A9J7GBR3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S203-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "MYO19", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQQVNGHGSGSDAHSGGESLREELQEFLGGEALLHQLDDLTQVNPVTLETVLRCLQARYSADMFYTNAGCTLVALNPFKPVPQLYSTELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLMEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSRESHKIAERIEQRILNSNPVMEAFGNAGTLRNNNSSRFGKFIQLQLNRTQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASADERLQWHLPEGATFSWLPNPERTLEEDCFEVTREAMLHLGIDAPTQNNIFQALAGLLHLGNIQFADSRDEAQPCQLMDSAKCSARTSASLLRLPEDLLLETLQIRTIRAGRQQQVFQKPCSRAECDTRRDCLAKLVYARLFDWLVSVINSSICADPDSWTTFIGLLDVYGFESFPNNSLEQLCINYANEKLQQHFVAHYLRAQQEEYAAEGLQWSFVNYQDNQTCLDLIEGSPISICSLMNEECRLNRPSSAAQLQTRIESALAGSPCLGHDKLSQEPSFIVVHYAGPVRYHTAGLVEKNKDPVPPELTRLLQQSQDPLLKVLFPPDPEEKSQEEPSGQSRTPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQGQAQMFHPEEVLSQLEACGLVETIHISAAGFPIRVSHRNFVERYELLRRLRPGTAPSQSADEGRSERSPRAEQATLQALFQDILHTLPALAQAAATPGDRAEATPAPVHCGRTKVFMTDSTLELLERGRAQVLEQCARCIQGGWRRHQRRKQERQRQAAVLIQAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMAFLASKELDGVEEKHSSQAPRSPSSLSLPQAQSRLPGGATRLWPLGLVLANAAVGVRGFQRKLVVFACLQLPVGAPSSYTIQTAQDQAGVMSIRALPQGSIRFRCRKSPLRYADICPQPSPDSVTGFNQILLERHKLGHV", "length": 962 }, "evidence": [ { "id": "A0A9J7GBR3", "url": "https://omabrowser.org/oma/group/A0A9J7GBR3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5SV80-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "Myo19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQQVNGHSLGSDAEGRASLKGDLREFLGGEIPLHQLDDLTKVNPVTLETVLRCLQARYTEDIFYTNAGCTLVALNPFKHVPQLYAPELMQEYHAAPQPQKLKPHIFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVAASPTSCENHKIAERIEQRILNSNPVMEAFGNACTLRNSNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGATKDERLQWHLPEGTAFSWLPNPESSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNVHFVDSEDEALPCQVMDDTKVSVRTSALLLQLPEKMLLESMQIRTIKAGKQQQVFQKPCSRAECDTRRDCLAKLIYARLFDWLVSVINSSICADSKSWTAFIGLLDVYGFESFPNNSLEQLCINYANEKLQQHFVAHYLRAQQEEYEVEGLEWSFVNYQDNQTCLDLLEGSPISICSLINEECRLNRPSSAAQLQTRIESTLAGRPCLGHNKLSREPSFVVVHFAGPVRYHTAGLVEKNKDPVPPELTELLQQSQDPLLTMLFPANPEEKTQEELSGQSRAPALTVVSKFKASLEQLLQVLHNTTPHYIRCIKPNSQSQPQTFLQEEVLNQLEACGLVETIHISAAGFPIRVSHQNFIERYKLLRRLGPRMSSGLGGLEPAEGSSEQPLCAKEATLQPLLQDILHALPALIQTAATPSDPAKNTQIPLYCGRTKIFMTDSMLELLECGRAQMLEQCARCIQCGWRRHRLQKQEKQRRAAVLIQAAFRSWLTRKHIRRLHIAATVIKHAWHKWRIRMACLASKELDGMEEKPMPQAPGTLRSSMSPAHTRFLGAIIHLWPLGLVLANSADGVRGFQRKLVAHACLRLPSDRPSNKVQTPQQDQAGITSIRALPQGSIKFHCRKSPLQYADICPDPSASCVTGFNQILLESHRPVQV", "length": 963 }, "evidence": [ { "id": "A0A9J7GBR3", "url": "https://omabrowser.org/oma/group/A0A9J7GBR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96H55-1", "protein_name": "Unconventional myosin-XIX", "gene_name": "MYO19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLRAQQEEYAVEGLEWSFINYQDNQPCLDLIEGSPISICSLINEECRLNRPSSAAQLQTRIETALAGSPCLGHNKLSREPSFIVVHYAGPVRYHTAGLVEKNKDPIPPELTRLLQQSQDPLLMGLFPTNPKEKTQEEPPGQSRAPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQGQAQTFLQEEVLSQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMACLAAKELDGVEEKHFSQAPCSLSTSPLQTRLLEAIIRLWPLGLVLANTAMGVGSFQRKLVVWACLQLPRGSPSSYTVQTAQDQAGVTSIRALPQGSIKFHCRKSPLRYADICPEPSPYSITGFNQILLERHRLIHVTSSAFTGLG", "length": 970 }, "evidence": [ { "id": "A0A9J7GBR3", "url": "https://omabrowser.org/oma/group/A0A9J7GBR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of mitochondrial fission", "id": "GO:0090140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090140", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "establishment of mitochondrion localization", "id": "GO:0051654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "myosin light chain binding", "id": "GO:0032027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032027", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "plus-end directed microfilament motor activity", "id": "GO:0060002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060002", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "microfilament motor activity", "id": "GO:0000146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000146", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "myosin complex", "id": "GO:0016459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016459", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GBR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR3" }, { "id": "PS51456", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51456" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myosin motor", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 773, "start_aa": "His", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 484, "end_pos": 486 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"mass": { "chemical_mass": 114194.0, "monoisotopic_mass": 114194.0 }, "refseq": { "ac": "XP_007640887", "name": "pumilio homolog 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640887" }, "gene_names": [ { "name": "Pum2", "type": "recommended", "evidence": [ { "id": "A0A9J7GC90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ] }, { "name": "Pum2", "type": "synonym", "evidence": [ { "id": "XP_007640887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640887" } ] } ], "protein_names": [ { "name": "Pumilio homolog 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7GC90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90/entry#names_and_taxonomy" } ] }, { "name": "pumilio homolog 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007640887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640887" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613876.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640887" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pum2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90", "locus": {} } ], "crossref": [ { "id": "cd07920", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07920", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100775042", "url": "https://www.ncbi.nlm.nih.gov/gene/100775042", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033712", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033712", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100775042", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775042", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RGMMHAN", "url": "https://omabrowser.org/oma/group/RGMMHAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2NCM5", "url": "https://www.orthodb.org/?gene=A0A8C2NCM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GAH0", "url": "https://www.orthodb.org/?gene=A0A9J7GAH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GAH3", "url": "https://www.orthodb.org/?gene=A0A9J7GAH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GC90", "url": "https://www.orthodb.org/?gene=A0A9J7GC90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GC91", "url": "https://www.orthodb.org/?gene=A0A9J7GC91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GEY8", "url": "https://www.orthodb.org/?gene=A0A9J7GEY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7KBR4", "url": "https://www.orthodb.org/?gene=A0A9J7KBR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HDJ2", "url": "https://www.orthodb.org/?gene=G3HDJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12537:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12537:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00806", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00806", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640887", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2NCM5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NCM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2NCM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2NCM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC90-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEY8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBR4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HDJ2", "url": "https://www.uniprot.org/uniprotkb/G3HDJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HDJ2-1", "url": "https://www.uniprot.org/uniprotkb/G3HDJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLADDEWRETAWGTSHHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKGDEKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPSTNPPEGLGSLPNPTANKPLVEEFSNPETQNLDAMDQVGLDSLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTANQQAASQAQPGQQQVLRAGAGQRPITPSQGQQGQQAESLAAAAAANPTLAFGQGLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQPQQQQPSSNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFSEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML", "length": 1066, "header": "tr|A0A9J7GC90-1|A0A9J7GC90_CRIGR Isoform 1 of Pumilio homolog 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pum2 PE=4 SV=1 CANONICAL=A0A9J7GC90-1" }, "isoforms": [ { "isoform_ac": "A0A8C2NCM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90/entry#A0A8C2NCM5-1", "sequence": { "sequence": "MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLADDEWRETAWGTSHHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKGDEKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPSTNPPEGLGSLPNPTANKPLVEEFSNPETQNLDAMDQVGLDSLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTANQQAASQAQPGQQQVLRAGAGQRPITPSQGQQGQQAESLAAAAAANPTLAFGQGLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQPQQQQPSSNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFSEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQSEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML", "length": 985, "header": "tr|A0A8C2NCM5-1|A0A8C2NCM5_CRIGR Computationally mapped isoform of Pumilio homolog 2 isoform X7 OS=Cricetulus griseus OX=10029 GN=Pum2 PE=4 SV=1 CANONICAL=A0A9J7GC90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90/entry#A0A9J7GAH0-1", "sequence": { "sequence": "MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLADDEWRETAWGTSHHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKGDEKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPSTNPPEGLGSLPNPTANKPLVEEFSNPETQNLDAMDQVGLDSLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTANQQAASQAQPGQQQVLRAGAGQRPITPSQGQQGQQAESLAAAAAANPTLAFGQGLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQPQQQQPSSNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFSEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML", "length": 987, "header": "tr|A0A9J7GAH0-1|A0A9J7GC90_CRIGR Computationally mapped isoform of Pumilio homolog 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pum2 PE=4 SV=1 CANONICAL=A0A9J7GC90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90/entry#A0A9J7GAH3-1", "sequence": { "sequence": "MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLADDEWRETAWGTSHHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKGDEKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPSTNPPEGLGSLPNPTANKPLVEEFSNPETQNLDAMDQVGLDSLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTANQQAASQAQPGQQQVLRAGAGQRPITPSQGQQGQQAESLAAAAAANPTLAFGQGLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQPQQQQPSSNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFSEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQSEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML", "length": 980, "header": "tr|A0A9J7GAH3-1|A0A9J7GC90_CRIGR Computationally mapped isoform of Pumilio homolog 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pum2 PE=4 SV=1 CANONICAL=A0A9J7GC90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GC90-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90/entry#A0A9J7GC90-1", "sequence": { "sequence": "MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLADDEWRETAWGTSHHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKGDEKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPSTNPPEGLGSLPNPTANKPLVEEFSNPETQNLDAMDQVGLDSLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTANQQAASQAQPGQQQVLRAGAGQRPITPSQGQQGQQAESLAAAAAANPTLAFGQGLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQPQQQQPSSNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFSEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML", "length": 1066, "header": "tr|A0A9J7GC90-1|A0A9J7GC90_CRIGR Isoform 1 of Pumilio homolog 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pum2 PE=4 SV=1 CANONICAL=A0A9J7GC90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GC91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90/entry#A0A9J7GC91-1", "sequence": { "sequence": "MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLADDEWRETAWGTSHHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKGDEKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPSTNPPEGLGSLPNPTANKPLVEEFSNPETQNLDAMDQVGLDSLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTANQQAASQAQPGQQQVLRAGAGQRPITPSQGQQGQQAESLAAAAAANPTLAFGQGLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQPQQQQPSSNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFSEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML", "length": 1065, "header": "tr|A0A9J7GC91-1|A0A9J7GC91_CRIGR Computationally mapped isoform of Pumilio homolog 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Pum2 PE=4 SV=1 CANONICAL=A0A9J7GC90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90/entry#A0A9J7GEY8-1", "sequence": { "sequence": "MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLADDEWRETAWGTSHHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKGDEKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPSTNPPEGLGSLPNPTANKPLVEEFSNPETQNLDAMDQVGLDSLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTANQQAASQAQPGQQQVLRAGAGQRPITPSQGQQGQQAESLAAAAAANPTLAFGQGLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQPQQQQPSSNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFSEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML", "length": 1061, "header": "tr|A0A9J7GEY8-1|A0A9J7GEY8_CRIGR Computationally mapped isoform of Pumilio homolog 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Pum2 PE=4 SV=1 CANONICAL=A0A9J7GC90-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90/entry#A0A9J7KBR4-1", "sequence": { "sequence": "MSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKGDEKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPSTNPPEGLGSLPNPTANKPLVEEFSNPETQNLDAMDQVGLDSLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTANQQAASQAQPGQQQVLRAGAGQRPITPSQGQQGQQAESLAAAAAANPTLAFGQGLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQPQQQQPSSNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFSEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQVISEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML", "length": 1010, "header": "tr|A0A9J7KBR4-1|A0A9J7KBR4_CRIGR Computationally mapped isoform of Pumilio homolog 2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Pum2 PE=4 SV=1 CANONICAL=A0A9J7GC90-1" }, "locus": {} }, { "isoform_ac": "G3HDJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90/entry#G3HDJ2-1", "sequence": { "sequence": "MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLADDEWRETAWGTSHHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKGDEKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPSTNPPEGLGSLPNPTANKPLVEEFSNPETQNLDAMDQVGLDSLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTANQQAASQAQPGQQQVLRAGAGQRPITPSQGQQGQQAESLAAAAAANPTLAFGQGLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQPQQQQPSSNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFSEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQSEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML", "length": 1064, "header": "tr|G3HDJ2-1|A0A9J7GC90_CRIGR Computationally mapped isoform of Pumilio homolog 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Pum2 PE=4 SV=1 CANONICAL=A0A9J7GC90-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HDJ2", "url": "https://www.uniprot.org/uniprotkb/G3HDJ2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HDJ2", "url": "https://www.uniprot.org/uniprotkb/G3HDJ2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100775042", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775042", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K8F9-1", "protein_name": "Pumilio RNA-binding family member 2", "gene_name": "Pum2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLGDDEWRETAWGTSHHSMSQPIMVQRRSGQSFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGTFGTRDAETDGPEKGDQKGKASPFEEDQNRDLKQDDEDSKINGRGLPNGMDADCKDFNRTPGSRQASPTEVVERLGPSTNPPEGLGPLPNPTANKPLVEEFSNPETQNLDAMDQVGLDSLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAAASNTANQQAASQAQPGQQQVLRPGAGQRPITPSQGQQGQQAESLAAAAAANPTLAFGQSLAAGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAAGGTANSLTGSTNGLFRPIGTQPPQQQQQQQPSTNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSASLGFGSGSSLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERATPAERQMVFNEIVQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALANRIRGHVLPLALQMYGCRVIQKALESISSDQQSEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML", "length": 1065 }, "evidence": [ { "id": "A0A9J7GC90", "url": "https://omabrowser.org/oma/group/A0A9J7GC90/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XR72-1", "protein_name": "Pumilio RNA binding family member 2", "gene_name": "PUM2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNHEFQALALESRGMGELLPAKKFWEPDDSAKDGQKGIFLGDEWRETAWGTPHHSMSQPIMVQRKPGQGFHGNSEVNAVLSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGAFGTRDAETDGPEKGDQKGKASPFEEDKNRDLKQGDDEDVTKINGRGLPNGMDADCKDFNRTPGSRQASPTEVAERLGPNPSTTEGLGPLPNPTAHKPLVEEFSNPENQNLDAMEQVGLDSLQFDYPGNQVQMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQQAAAANTTANQQAASQAQQGQQPVLRAGATQRPLTPSQGQQGQQAESLAAAAAANPALAFGQGLATGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLVASTPVIISSAAAQAAAAASAGGTANNLTGATNGLFRPLGAQPQQQQQQTNSSLQSNSFYGSNSLTNNSPNSSLFSHGPGQPGSTSLGFGSSSSLGAAIGSALGGFGSSVGSSASSSATRRDSLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYISAAPGAEAKYRSAASTSSLFSSTSQLFPPSRLRYSRSDIMPSGRSRLLEDFRNNRFPNLQLRDLIGHIVEFSQDQHGSRFIQQKLERATPAERQMVFNEILQAAYQLMTDVFGNYVIQKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISPDQQVINEMVKELDGHVLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVVEKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYLKNSADLGPIGGPPNGML", "length": 1064 }, "evidence": [ { "id": "A0A9J7GC90", "url": "https://omabrowser.org/oma/group/A0A9J7GC90/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q80U58-1", "protein_name": "Pumilio homolog 2", "gene_name": "Pum2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"length": 1066 }, "evidence": [ { "id": "A0A9J7GC90", "url": "https://omabrowser.org/oma/group/A0A9J7GC90/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 11, "go_terms": [ { "name": "adipose tissue development", "id": "GO:0060612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060612", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "hair follicle development", "id": "GO:0001942", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001942", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "positive regulation of RIG-I signaling pathway", "id": "GO:1900246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900246", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "miRNA processing", "id": "GO:0035196", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035196", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "positive regulation of miRNA-mediated gene silencing", "id": "GO:2000637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000637", "evidence": 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"url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035198", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "lncRNA binding", "id": "GO:0106222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106222", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" }, { "name": "pumilio-response element binding", "id": "GO:0062104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0062104", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC90" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, 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"synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 657, "end_pos": 659 }, { "start_pos": 698, "end_pos": 700 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"https://www.ncbi.nlm.nih.gov/protein/XP_007644368" }, "gene_names": [ { "name": "Ppfia1", "type": "recommended", "evidence": [ { "id": "A0A9J7JI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98" } ] }, { "name": "Ppfia1", "type": "synonym", "evidence": [ { "id": "XP_007644368", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644368" } ] } ], "protein_names": [ { "name": "Liprin-alpha-1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7JI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98/entry#names_and_taxonomy" } ] }, { "name": "liprin-alpha-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007644368", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644368" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614178.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007644368.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644368", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644368" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppfia1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98", "locus": {} } ], "crossref": [ { "id": "cd09562", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09562", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09565", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09565", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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"Protein Classification" ] }, { "id": "IPR037622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773150", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773150", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FNV9", "url": "https://www.orthodb.org/?gene=A0A9J7FNV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JE25", "url": "https://www.orthodb.org/?gene=A0A9J7JE25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JI98", "url": "https://www.orthodb.org/?gene=A0A9J7JI98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JKX5", "url": "https://www.orthodb.org/?gene=A0A9J7JKX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HQ70", "url": "https://www.orthodb.org/?gene=G3HQ70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12587:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25526", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25526", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644368", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644368", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FNV9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FNV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JE25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JE25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI98-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HQ70", "url": "https://www.uniprot.org/uniprotkb/G3HQ70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HQ70-1", "url": "https://www.uniprot.org/uniprotkb/G3HQ70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMCEVMPTISEAEGPPGGGGSRGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGMLDGNHEQENTPSTNGKRSSDSSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALRTELDQMRLRGPSLHHGRPHLGSVPDFRFPVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPAYPASSIAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQVGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWLTHEEMETLTVTPQTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC", "length": 1222, "header": "tr|A0A9J7JI98-1|A0A9J7JI98_CRIGR Isoform 1 of Liprin-alpha-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfia1 PE=3 SV=1 CANONICAL=A0A9J7JI98-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FNV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98/entry#A0A9J7FNV9-1", "sequence": { "sequence": "MMCEVMPTISEAEGPPGGGGSRGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGMLDGNHEQENTPSTNGKRSSDSSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALRTELDQMRLRGPSLHHGRPHLGSVPDFRFPVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPAYPASSIAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQVGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDVYPHYFYR", "length": 1190, "header": "tr|A0A9J7FNV9-1|A0A9J7JI98_CRIGR Computationally mapped isoform of Liprin-alpha-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfia1 PE=3 SV=1 CANONICAL=A0A9J7JI98-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JE25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98/entry#A0A9J7JE25-1", "sequence": { "sequence": "MMCEVMPTISEAEGPPGGGGSRGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGMLDGNHEQENTPSTNGKRSSDSSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALRTELDQMRLRGPSLHHGRPHLGSVPDFRFPVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPAYPASSIAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQVGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWLTHEEMETLTVTPQTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDVYPHYFYR", "length": 1211, "header": "tr|A0A9J7JE25-1|A0A9J7JE25_CRIGR Computationally mapped isoform of Liprin-alpha-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ppfia1 PE=3 SV=1 CANONICAL=A0A9J7JI98-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JI98-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98/entry#A0A9J7JI98-1", "sequence": { "sequence": "MMCEVMPTISEAEGPPGGGGSRGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGMLDGNHEQENTPSTNGKRSSDSSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALRTELDQMRLRGPSLHHGRPHLGSVPDFRFPVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPAYPASSIAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQVGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWLTHEEMETLTVTPQTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC", "length": 1222, "header": "tr|A0A9J7JI98-1|A0A9J7JI98_CRIGR Isoform 1 of Liprin-alpha-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfia1 PE=3 SV=1 CANONICAL=A0A9J7JI98-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98/entry#A0A9J7JKX5-1", "sequence": { "sequence": "MMCEVMPTISEAEGPPGGGGSRGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGMLDGNHEQENTPSTNGKRSSDSSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALRTELDQMRLRGPSLHHGRPHLGSVPDFRFPVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPAYPASSIAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQVGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC", "length": 1202, "header": "tr|A0A9J7JKX5-1|A0A9J7JKX5_CRIGR Computationally mapped isoform of Liprin-alpha-1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ppfia1 PE=3 SV=1 CANONICAL=A0A9J7JI98-1" }, "locus": {} }, { "isoform_ac": "G3HQ70-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98/entry#G3HQ70-1", "sequence": { "sequence": "MMCEVMPTISEAEGPPGGGGSRGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGMLDGNHEQENTPSTNGKRSSDSSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALRTELDQMRLRGPSLHHGRPHLGSVPDFRFPVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPAYPASSIAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQVGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC", "length": 1201, "header": "tr|G3HQ70-1|A0A9J7JI98_CRIGR Computationally mapped isoform of Liprin-alpha-1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ppfia1 PE=3 SV=1 CANONICAL=A0A9J7JI98-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HQ70", "url": "https://www.uniprot.org/uniprotkb/G3HQ70" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HQ70", "url": "https://www.uniprot.org/uniprotkb/G3HQ70" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773150", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773150", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98" } ], "pmid": "" }, { "name": "presynaptic active zone", "id": "GO:0048786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "synapse organization", "id": "GO:0050808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI98", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1063, "end_pos": 1065, "annotation": "n_glycosylation_sequon" }, { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" }, { "start_pos": 787, "end_pos": 789, "annotation": "n_glycosylation_sequon" }, { "start_pos": 836, "end_pos": 838, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JI98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI98" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 877, "end_pos": 943, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1063, "end_pos": 1065 }, { "start_pos": 119, "end_pos": 121 }, { "start_pos": 771, "end_pos": 773 }, { "start_pos": 787, "end_pos": 789 }, { "start_pos": 836, "end_pos": 838 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": 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"title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JHW9-1", "uniprot_ac": "A0A9J7JHW9", "uniprot_id": "A0A9J7JHW9_CRIGR", "mass": { "chemical_mass": 70519.0, "monoisotopic_mass": 70519.0 }, "refseq": { "ac": "XP_007652646", "name": "seipin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652646" }, "gene_names": [ { "name": "Bscl2", "type": "recommended", "evidence": [ { "id": "A0A9J7JHW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9" } ] }, { "name": "Bscl2", "type": "synonym", "evidence": [ { "id": "XP_007652646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652646" } ] } ], "protein_names": [ { "name": "Seipin isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7JHW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9/entry#names_and_taxonomy" } ] }, { "name": "seipin isoform X1", "type": 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This record is derived from a genomic sequence (NW_003616501.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007652646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652646" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bscl2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHW9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23993", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23993", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755147", "url": "https://www.ncbi.nlm.nih.gov/gene/100755147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755147", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755147", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GU51", "url": "https://www.orthodb.org/?gene=A0A9J7GU51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JDQ8", "url": "https://www.orthodb.org/?gene=A0A9J7JDQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JHW9", "url": "https://www.orthodb.org/?gene=A0A9J7JHW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3II38", "url": "https://www.orthodb.org/?gene=G3II38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21212", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21212", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21212:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21212:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007652646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652646", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GU51", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GU51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GU51-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GU51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDQ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHW9", "url": 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"MIQQRREAGGKQTCKDQMKKGSDKEEEPPAALSHGQGYRPCGRPTRNSKPEAGARSSAVPIMVNDPPIPAFLWAQEVGHVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFHYRTDCDSSTALLCSFPVANVSLAKNGRDRVLMYGQPYRVTLELEMPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHYRSQLLQMLDTLVFSSLLLFGFAEQKQLLEVEVYSDYRENSYVPTTGAVIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIVLFSYMQWVWGGIWPQHRFSLQVNIRQRDSSRQGTQHRTSRHQPGQESTQQSDVTEDGESPEDRPGTEGKRSEEEKPPRQPLNGEEEQEREASDDSMLGSFYLLWLVAMTTSLVSKAQILTPQDYEEEDDEAVTTPSVAVPCDYDRCRHLQVPCKELQKVGPVACLCPGLSREDEQPDPPRLGEVQIVAEEGCVLVHWCAPFSPVNHYWLLLWESNGVPQKSGPLNATVRRAELKGLKPGGTYVLCVVAANEAGESHVPEADVENWADPSFGPCGKLIMPPRPLTLVYAAMGVGTALALLSCAALVWHFCLREQCGCPRR", "length": 630, "header": "tr|A0A9J7JHW9-1|A0A9J7JHW9_CRIGR Isoform 1 of Seipin isoform X1 OS=Cricetulus griseus OX=10029 GN=Bscl2 PE=4 SV=1 CANONICAL=A0A9J7JHW9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GU51-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9/entry#A0A9J7GU51-1", "sequence": { "sequence": 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"MVNDPPIPAFLWAQEVGHVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFHYRTDCDSSTALLCSFPVANVSLAKNGRDRVLMYGQPYRVTLELEMPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHYRSQLLQMLDTLVFSSLLLFGFAEQKQLLEVEVYSDYRENSYVPTTGAVIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIVLFSYMQWVWGGIWPQHRFSLQVNIRQRDSSRQGTQHRTSRHQPGQESTQQSDVTEDGESPEDRPGTEGKRSEEEKPPRQPLNGEEEQEREASDDSMLGSFYLLWLVAMTTSLVSKAQILTPQDYEEEDDEAVTTPSVAVPCDYDRCRHLQVPCKELQKVGPVACLCPGLSREDEQPDPPRLGEVQIVAEEGCVLVHWCAPFSPVNHYWLLLWESNGVPQKSGPLNATVRRAELKGLKPGGTYVLCVVAANEAGESHVPEADVENWADPSFGPCGKLIMPPRPLTLVYAAMGVGTALALLSCAALVWHFCLREQCGCPRR", "length": 569, "header": "tr|A0A9J7JDQ8-1|A0A9J7JDQ8_CRIGR Computationally mapped isoform of Seipin isoform X2 OS=Cricetulus griseus OX=10029 GN=Bscl2 PE=4 SV=1 CANONICAL=A0A9J7JHW9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9/entry#A0A9J7JHW9-1", "sequence": { "sequence": "MIQQRREAGGKQTCKDQMKKGSDKEEEPPAALSHGQGYRPCGRPTRNSKPEAGARSSAVPIMVNDPPIPAFLWAQEVGHVLAGRARRLLLQFGVLFCTILLLLWVSVFLYGSFYYSYMPTVSHLSPVHFHYRTDCDSSTALLCSFPVANVSLAKNGRDRVLMYGQPYRVTLELEMPESPVNQDLGMFLVTVSCYTRGGRIISTSSRSVMLHYRSQLLQMLDTLVFSSLLLFGFAEQKQLLEVEVYSDYRENSYVPTTGAVIEIHSKRIQLYGAYLRIHAHFTGLRYLLYNFPMTCAFVGVASNFTFLSVIVLFSYMQWVWGGIWPQHRFSLQVNIRQRDSSRQGTQHRTSRHQPGQESTQQSDVTEDGESPEDRPGTEGKRSEEEKPPRQPLNGEEEQEREASDDSMLGSFYLLWLVAMTTSLVSKAQILTPQDYEEEDDEAVTTPSVAVPCDYDRCRHLQVPCKELQKVGPVACLCPGLSREDEQPDPPRLGEVQIVAEEGCVLVHWCAPFSPVNHYWLLLWESNGVPQKSGPLNATVRRAELKGLKPGGTYVLCVVAANEAGESHVPEADVENWADPSFGPCGKLIMPPRPLTLVYAAMGVGTALALLSCAALVWHFCLREQCGCPRR", "length": 630, "header": "tr|A0A9J7JHW9-1|A0A9J7JHW9_CRIGR Isoform 1 of Seipin isoform X1 OS=Cricetulus griseus OX=10029 GN=Bscl2 PE=4 SV=1 CANONICAL=A0A9J7JHW9-1" }, "locus": {} }, { "isoform_ac": "G3II38-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9/entry#G3II38-1", "sequence": { "sequence": "MLGSFYLLWLVAMTTSLVSKAQILTPQDYEEEDDEAVTTPSVAVPCDYDRCRHLQVPCKELQKVGPVACLCPGLSREDEQPDPPRLGEVQIVAEEGCVLVHWCAPFSPVNHYWLLLWESNGVPQKSGPLNATVRRAELKGLKPGGTYVLCVVAANEAGESHVPEADVENWADPSFGPCGKLIMPPRPLTLVYAAMGVGTALALLSCAALVWHFCLREQCGCPRR", "length": 224, "header": "tr|G3II38-1|A0A9J7JHW9_CRIGR Computationally mapped isoform of Seipin isoform X1 OS=Cricetulus griseus OX=10029 GN=Bscl2 PE=4 SV=1 CANONICAL=A0A9J7JHW9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3II38", "url": "https://www.uniprot.org/uniprotkb/G3II38" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3II38", "url": "https://www.uniprot.org/uniprotkb/G3II38" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755147", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755147", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9" } ], "pmid": "" }, { "name": "lipid droplet formation", "id": "GO:0140042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140042", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JHW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW9" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 486, "end_pos": 580, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 303, "end_pos": 305 }, { "start_pos": 536, "end_pos": 538 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265555" } ] }, { "annotation": "Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVH9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVH9#function" }, { "database": "UniProtKB", "id": "PIRNR037942", "url": "https://www.uniprot.org/uniprotkb/PIRNR037942#function" }, { "database": "UniProtKB", "id": "A0A9J7JLK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLK7#function" }, { "database": "UniProtKB", "id": "A0A9J7JIW9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW9#function" }, { "database": "UniProtKB", "id": "A0A8C2LTL1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": 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"IPR002119", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002119", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771856", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771856", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHHFPAK", "url": "https://omabrowser.org/oma/group/GHHFPAK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JIW9", "url": "https://www.orthodb.org/?gene=A0A9J7JIW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16211", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16211", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LTL1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LTL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVH9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GTB9", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISNYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN", "length": 372, "header": "tr|A0A9J7JIW9-1|A0A9J7JIW9_CRIGR Isoform 1 of Core histone macro-H2A OS=Cricetulus griseus OX=10029 GN=LOC100771856 PE=4 SV=1 CANONICAL=A0A9J7JIW9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LTL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW9/entry#A0A8C2LTL1-1", "sequence": { "sequence": "MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISNYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN", "length": 369, "header": "tr|A0A8C2LTL1-1|A0A8C2LTL1_CRIGR Computationally mapped isoform of Core histone macro-H2A OS=Cricetulus griseus OX=10029 GN=LOC100771856 PE=4 SV=1 CANONICAL=A0A9J7JIW9-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LVH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW9/entry#A0A8C2LVH9-1", "sequence": { "sequence": "MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISNYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN", "length": 371, "header": "tr|A0A8C2LVH9-1|A0A9J7JIW9_CRIGR Computationally mapped isoform of Core histone macro-H2A OS=Cricetulus griseus OX=10029 GN=LOC100771856 PE=4 SV=1 CANONICAL=A0A9J7JIW9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GTB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW9/entry#A0A9J7GTB9-1", "sequence": { "sequence": "MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKMGWHLTLPCPCLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISNYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN", "length": 351, "header": "tr|A0A9J7GTB9-1|A0A9J7GTB9_CRIGR Computationally mapped isoform of Core histone macro-H2A.1 isoform X5 OS=Cricetulus griseus OX=10029 GN=LOC100771856 PE=4 SV=1 CANONICAL=A0A9J7JIW9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW9/entry#A0A9J7GYQ2-1", "sequence": { "sequence": "MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKMGWHLTLPCPCLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISNYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN", "length": 350, "header": "tr|A0A9J7GYQ2-1|A0A9J7GYQ2_CRIGR Computationally mapped isoform of Core histone macro-H2A.1 isoform X6 OS=Cricetulus griseus OX=10029 GN=LOC100771856 PE=4 SV=1 CANONICAL=A0A9J7JIW9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW9/entry#A0A9J7JIW9-1", "sequence": { "sequence": "MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLNLIHSEISNLAGFEVEAIINPTNADIDLKDDLGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISNYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN", "length": 372, "header": "tr|A0A9J7JIW9-1|A0A9J7JIW9_CRIGR Isoform 1 of Core histone macro-H2A OS=Cricetulus griseus OX=10029 GN=LOC100771856 PE=4 SV=1 CANONICAL=A0A9J7JIW9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW9/entry#A0A9J7JLK7-1", "sequence": { "sequence": "MSSRGGKKKSTKTSRSAKAGVIFPVGRMLRYIKKGHPKYRIGVGAPVYMAAVLEYLTAEILELAGNAARDNKKGRVTPRHILLAVANDEELNQLLKGVTIASGGVLPNIHPELLAKKRGSKGKLEAIITPPPAKKAKSPSQKKPVAKKTGGKKGARKSKKQGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFYIGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISNYFVSTMSSSIKTVYFVLFDSESIGIYVQEMAKLDAN", "length": 368, "header": "tr|A0A9J7JLK7-1|A0A9J7JLK7_CRIGR Computationally mapped isoform of Core histone macro-H2A OS=Cricetulus griseus OX=10029 GN=LOC100771856 PE=4 SV=1 CANONICAL=A0A9J7JIW9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVH9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVH9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVH9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVH9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771856", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771856", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B3D7-1", "protein_name": "Core histone macro-H2A", "gene_name": "MACROH2A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JIZ0-1", "uniprot_ac": "A0A9J7JIZ0", "uniprot_id": "A0A9J7JIZ0_CRIGR", "mass": { "chemical_mass": 113826.0, "monoisotopic_mass": 113826.0 }, "refseq": { "ac": "XP_027262723", "name": "DNA cross-link repair 1A protein isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262723" }, "gene_names": [ { "name": "Dclre1a", "type": "recommended", "evidence": [ { "id": "A0A9J7JIZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ] }, { "name": "Dclre1a", "type": "synonym", "evidence": [ { "id": "XP_027262723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262723" } ] } ], "protein_names": [ { "name": "DNA cross-link repair 1A protein isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027262723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262723" }, { "id": "A0A9J7JIZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262723" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dclre1a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0", "locus": {} } ], "crossref": [ { "id": "A0A9J7JIZ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JIZ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100750521", "url": "https://www.ncbi.nlm.nih.gov/gene/100750521", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750521", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750521", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JIZ0", "url": "https://www.orthodb.org/?gene=A0A9J7JIZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23240:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23240:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20401", "url": "https://www.rhea-db.org/rhea/20401", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FLI2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLEDEFWEEDIWKYKSKRKPKPAHPINCSQNISESVGRTTDGKRKGNKKRNEEDKDKTKDHRVCLGEADSQSSVGSSQNLSGRDEVQESQSKETTPRKPCRTHKNKQLSPRVRPVYDGHCPSCQMPFSSLLGQTPRWHVFECLDSPPISDTECPEGLLCTSTIPSHYKKYTHLLLAQSRASNEPSSSPSHMPAGRFTEAKPASSCNLEERWPVHLKAENLRVLDDSLLIQCLKTSALPPETNRKNPPSTNSQMSLVPQCTEPVKKDKLVGGGLPLPEDALSSQSASQGTNLPSPESDCGGCEISYSPLQSDEETYDLDQELDDSQQELFCTQSSKDSSLEDDGSPIFENFHDPFPREPEGVFPTAESLVTRADCNRLCKGSVLSDSFQLLSQTESRLSQDDPPSPDAGFLLFSPASAAGPAASNYQATKAKPGEPEESRSLGSSHQKGKMATSAVGSQIPLPLRASAMSKPMEKEGGEHQPLHPTQSQIGGLRRESLGATIANSACACRKVEKPSIAVLAKSLSPLPSSPKCSASQPSKKVMKQMDIGVFFGLPPKRQEPSLRESVSGEPNVNPVASPNKKRPRPCKRKAENSLSDSELHSGDLNESQHSMEQPGERAQRRRKRHKKSDSPQQRSGHPINNPELGTVSLNKSRAFGRRTHGRPQRGSTGTSKWSGSRELRRACPFYKRIPGTGFTVDAFQYGEVEGCTAYFLTHFHSDHYAGLSKDFERPIYCSEITGNLVKKKLRVQEQYIHQLPMDTECIVDGVKVVLLDANHFSVLLTAPPYCTLETSEPTPAWSAPFSQARKSTHCHWWPLSVSYSCPCHRYCSPEYTFPSQQEVIQFAINTAFEAVTLNPRALVVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLKCLNLPDVNSLITTDMCSSLVHLLPMMQINFKGLQSHLEKCDGKYDQILAFRPTGWTHSNRITSIADITPQKKGKISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGTFKSRDTMEKYFKEWRLEAGY", "length": 1025, "header": "tr|A0A9J7JIZ0-1|A0A9J7JIZ0_CRIGR Isoform 1 of DNA cross-link repair 1A protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Dclre1a PE=3 SV=1 CANONICAL=A0A9J7JIZ0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FLI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0/entry#A0A9J7FLI2-1", "sequence": { "sequence": "MLEDEFWEEDIWKYKSKRKPKPAHPINCSQNISESVGRTTDGKRKGNKKRNEEDKDKTKDHRVCLGEADSQSSVGSSQNLSGRDEVQESQSKETTPRKPCRTHKNKQLSPRVRPVYDGHCPSCQMPFSSLLGQTPRWHVFECLDSPPISDTECPEGLLCTSTIPSHYKKYTHLLLAQSRASNEPSSSPSHMPAGRFTEAKPASSCNLEERWPVHLKAENLRVLDDSLLIQCLKTSALPPETNRKNPPSTNSQMSLVPQCTEPVKKDKLVGGGLPLPEDALSSQSASQGTNLPSPESDCGGCEISYSPLQSDEETYDLDQELDDSQQELFCTQSSKDSSLEDDGSPIFENFHDPFPREPEGVFPTAESLVTRADCNRLCKGSVLSDSFQLLSQTESRLSQDDPPSPDAGFLLFSPASAAGPAASNYQATKAKPGEPEESRSLGSSHQKGKMATSAVGSQIPLPLRASAMSKPMEKEGGEHQPLHPTQSQIGGLRRESLGATIANSACACRKVEKPSIAVLAKSLSPLPSSPKCSASQPSKKVMKQMDIGVFFGLPPKRQEPSLRESVSGEPNVNPVASPNKKRPRPCKRKAENSLSDSELHSGDLNESQHSMEQPGERAQRRRKRHKKSDSPQQRSGHPINNPELGTVSLNKSRAFGRRTHGRPQRGSTGTSKWSGSRELRRACPFYKRIPGTGFTVDAFQYGEVEGCTAYFLTHFHSDHYAGLSKDFERPIYCSEITGNLVKKKLRVQEQYIHQLPMDTECIVDGVKVVLLDANHCPGASMILFRPPNGAAILHTGDFRADPSMERSLLAGQKVHTLYLDTTYCSPEYTFPSQQEVIQFAINTAFEAVTLNPRALVVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLKCLNLPDVNSLITTDMCSSLVHLLPMMQINFKGLQSHLEKCDGKYDQILAFRPTGWTHSNRITSIADITPQKKGKISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGTFKSRDTMEKYFKEWRLEAGY", "length": 1022, "header": "tr|A0A9J7FLI2-1|A0A9J7JIZ0_CRIGR Computationally mapped isoform of DNA cross-link repair 1A protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Dclre1a PE=3 SV=1 CANONICAL=A0A9J7JIZ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0/entry#A0A9J7JIZ0-1", "sequence": { "sequence": "MLEDEFWEEDIWKYKSKRKPKPAHPINCSQNISESVGRTTDGKRKGNKKRNEEDKDKTKDHRVCLGEADSQSSVGSSQNLSGRDEVQESQSKETTPRKPCRTHKNKQLSPRVRPVYDGHCPSCQMPFSSLLGQTPRWHVFECLDSPPISDTECPEGLLCTSTIPSHYKKYTHLLLAQSRASNEPSSSPSHMPAGRFTEAKPASSCNLEERWPVHLKAENLRVLDDSLLIQCLKTSALPPETNRKNPPSTNSQMSLVPQCTEPVKKDKLVGGGLPLPEDALSSQSASQGTNLPSPESDCGGCEISYSPLQSDEETYDLDQELDDSQQELFCTQSSKDSSLEDDGSPIFENFHDPFPREPEGVFPTAESLVTRADCNRLCKGSVLSDSFQLLSQTESRLSQDDPPSPDAGFLLFSPASAAGPAASNYQATKAKPGEPEESRSLGSSHQKGKMATSAVGSQIPLPLRASAMSKPMEKEGGEHQPLHPTQSQIGGLRRESLGATIANSACACRKVEKPSIAVLAKSLSPLPSSPKCSASQPSKKVMKQMDIGVFFGLPPKRQEPSLRESVSGEPNVNPVASPNKKRPRPCKRKAENSLSDSELHSGDLNESQHSMEQPGERAQRRRKRHKKSDSPQQRSGHPINNPELGTVSLNKSRAFGRRTHGRPQRGSTGTSKWSGSRELRRACPFYKRIPGTGFTVDAFQYGEVEGCTAYFLTHFHSDHYAGLSKDFERPIYCSEITGNLVKKKLRVQEQYIHQLPMDTECIVDGVKVVLLDANHFSVLLTAPPYCTLETSEPTPAWSAPFSQARKSTHCHWWPLSVSYSCPCHRYCSPEYTFPSQQEVIQFAINTAFEAVTLNPRALVVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLKCLNLPDVNSLITTDMCSSLVHLLPMMQINFKGLQSHLEKCDGKYDQILAFRPTGWTHSNRITSIADITPQKKGKISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGTFKSRDTMEKYFKEWRLEAGY", "length": 1025, "header": "tr|A0A9J7JIZ0-1|A0A9J7JIZ0_CRIGR Isoform 1 of DNA cross-link repair 1A protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Dclre1a PE=3 SV=1 CANONICAL=A0A9J7JIZ0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0/entry#A0A9J7JJI0-1", "sequence": { "sequence": "MLEDEFWEEDIWKYKSKRKPKPAHPINCSQNISESVGRTTDGKRKGNKKRNEEDKDKTKDHRVCLGEADSQSSVGSSQNLSGRDEVQESQSKETTPRKPCRTHKNKQLSPRVRPVYDGHCPSCQMPFSSLLGQTPRWHVFECLDSPPISDTECPEGLLCTSTIPSHYKKYTHLLLAQSRASNEPSSSPSHMPAGRFTEAKPASSCNLEERWPVHLKAENLRVLDDSLLIQCLKTSALPPETNRKNPPSTNSQMSLVPQCTEPVKKDKLVGGGLPLPEDALSSQSASQGTNLPSPESDCGGCEISYSPLQSDEETYDLDQELDDSQQELFCTQSSKDSSLEDDGSPIFENFHDPFPREPEGVFPTAESLVTRADCNRLCKGSVLSDSFQLLSQTESRLSQDDPPSPDAGFLLFSPASAAGPAASNYQATKAKPGEPEESRSLGSSHQKGKMATSAVGSQIPLPLRASAMSKPMEKEGGEHQPLHPTQSQIGGLRRESLGATIANSACACRKVEKPSIAVLAKSLSPLPSSPKCSASQPSKKVMKQMDIGVFFGLPPKRQEPSLRESVSGEPNVNPVASPNKKRPRPCKRKAENSLSDSELHSGDLNESQHSMEQPGERAQRRRKRHKKSDSPQQRSGHPINNPELGTVSLNKSRAFGRRTHGRPQRGSTGTSKWSGSRELRRACPFYKRIPGTGFTVDAFQYGEVEGCTAYFLTHFHSDHYAGLSKDFERPIYCSEITGNLVKKKLRVQEQYIHQLPMDTECIVDGVKVVLLDANHCPGASMILFRPPNGAAILHTGDFRADPSMERSLLAGQKVHTLYLDTTHC", "length": 824, "header": "tr|A0A9J7JJI0-1|A0A9J7JJI0_CRIGR Computationally mapped isoform of DNA cross-link repair 1A protein isoform X2 OS=Cricetulus griseus OX=10029 GN=Dclre1a PE=4 SV=1 CANONICAL=A0A9J7JIZ0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 794, "start_aa": "Thr", "end_pos": 794, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr794", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FLI2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLI2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FLI2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLI2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750521", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750521", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ], "pmid": "" }, { "name": "damaged DNA binding", "id": "GO:0003684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ], "pmid": "" }, { "name": "5'-3' DNA exonuclease activity", "id": "GO:0035312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035312", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ], "pmid": "" }, { "name": "beta-lactamase activity", "id": "GO:0008800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008800", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ], "pmid": "" }, { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20401", "name": "", "equation": "a beta-lactam + H2O = a substituted beta-amino acid", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRR5-1", "G3HQI1-1", "G3HL72-1", "A0A9J7JIZ0-1" ], "evidence": [ { "id": "20401", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20401" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7JIZ0", "gene_name": "Dclre1a", "activity": [ { "ec_number": "3.5.2.6", "activity": "a beta-lactam + H2O = a substituted beta-amino acid.", "evidence": [ { "id": "A0A9J7JIZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ] }, { "ec_number": "3.5.2.6", "activity": "", "evidence": [ { "id": "A0A9J7JIZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" } ] } ] }, { "uniprot_ac": "G3GRR5", "gene_name": "Dpep1", "activity": [ { "ec_number": "3.4.13.19", "activity": "an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid.", "evidence": [ { "id": "G3GRR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR5" } ] }, { "ec_number": "3.4.13.19", "activity": "", "evidence": [ { "id": "G3GRR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR5" } ] } ] }, { "uniprot_ac": "G3HL72", "gene_name": "Mblac2", "activity": [ { "ec_number": "3.1.2.2", "activity": "hexadecanoyl-CoA + H2O = hexadecanoate + CoA + H(+).", "evidence": [ { "id": "G3HL72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HL72" } ] }, { "ec_number": "3.5.2.6", "activity": "a beta-lactam + H2O = a substituted beta-amino acid.", "evidence": [ { "id": "G3HL72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HL72" } ] }, { "ec_number": "3.5.2.6", "activity": "", "evidence": [ { "id": "G3HL72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HL72" } ] }, { "ec_number": "3.1.2.2", "activity": "", "evidence": [ { "id": "G3HL72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HL72" } ] } ] }, { "uniprot_ac": "G3HQI1", "gene_name": "Dclre1b", "activity": [ { "ec_number": "3.5.2.6", "activity": "a beta-lactam + H2O = a substituted beta-amino acid.", "evidence": [ { "id": "G3HQI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HQI1" } ] }, { "ec_number": "3.5.2.6", "activity": "", "evidence": [ { "id": "G3HQI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HQI1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JIZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIZ0" }, { "id": "PS51908", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBZ4-type", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 147, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.5.2.6", "ec_name": "a beta-lactam + H2O = a substituted beta-amino acid.", "evidence": [ { "id": "3.5.2.6", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.2.6" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 794 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 605, "end_pos": 607 }, { "start_pos": 650, "end_pos": 652 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JI46-1", "uniprot_ac": "A0A9J7JI46", "uniprot_id": "A0A9J7JI46_CRIGR", "mass": { "chemical_mass": 87794.0, "monoisotopic_mass": 87794.0 }, "refseq": { "ac": "XP_027264440", "name": "ras and Rab interactor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264440" }, "gene_names": [ { "name": "Rin1", "type": "recommended", "evidence": [ { "id": "A0A9J7JI46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI46" } ] }, { "name": "Rin1", "type": "synonym", "evidence": [ { "id": "XP_027264440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264440" } ] } ], "protein_names": [ { "name": "Ras and Rab interactor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7JI46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI46/entry#names_and_taxonomy" } ] }, { "name": "ras and Rab interactor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027264440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264440" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264440" } ] }, { "annotation": "Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FNW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNW8#function" }, { "database": "UniProtKB", "id": "ARBA00055716", "url": "https://www.uniprot.org/uniprotkb/ARBA00055716#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI46" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rin1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI46", "locus": {} } ], "crossref": [ { "id": "A0A9J7JI46", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JI46", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd10393", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10393", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762837", "url": "https://www.ncbi.nlm.nih.gov/gene/100762837", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762837", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762837", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JI46", "url": "https://www.orthodb.org/?gene=A0A9J7JI46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23101:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23101:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23268", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23268", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027264440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264440", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FNW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FNW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCPPVPWGLDSLPESQEKLKELLAMEDPGDTEAHPLGTANLNFVPGHQQKENPSPDPLYDTPDASRAQAGGAQQPARTVSLRERLLITRPVWLQLRANAAAALHVLRTEPPGTFLVRKSNTRQCRALCVRLPEASGPSFVSSHYIQESPGGISLEGSELVFQDLVQLICAYCHTRDILLLPLRLPRAIHQATTHKELEAISHLGMEFWSSSLNTKVQQRPCEAPPIPRLKARSPQELDQGTGAALCFFNPLFPGDLGPTKREKFKRSFKVRVSTETSSPLSPPAVPPPPVPVLPGTSSSQTARLPPRQLLERESSMGYRVPGSASGQSLPPLPSLQEADCCSPSSSEEEGSPRSPTTSPRLGRPRQRPPLLRSMSSAFCSLLAPERQVGRAATTLMQNRYTAVGQLVQDLLTQVRAGPEPRELQGIRQALSRARAMLSAELGPEKLLPPERLELVLEKSLHRSVLKPLRPILVARLRRRLSADGSLGRLAEGFHLARTQGPGALGSHLPLSYPVETEQVRQKLLQLLGTYSPTAQIKWLLQACKLLYTALKTQAGEDAGADEFLPLLSLVLAQCDLPDLLLEAEYMSELLEPTLLTGEGEGTLTSCPGGYYLTSLSASLALLSGLSQARALPLSPAQELQRSLALWEQRRLPATYNFQHLLRVAYQDPSTGCTSKTLAVPPGSSIATLSQLCATKFRVTHPDAFGLFLYKDQGYHRLPPEALAHGLPATGYLIYRRAERPETQGAATEKAKAGSERQEAGAWEEEKGGGNSEGELETTVDQGGGENQARGGRVQPEEQKAEGSQAAEE", "length": 808, "header": "tr|A0A9J7JI46-1|A0A9J7JI46_CRIGR Isoform 1 of Ras and Rab interactor 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rin1 PE=3 SV=1 CANONICAL=A0A9J7JI46-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FNW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI46/entry#A0A9J7FNW8-1", "sequence": { "sequence": "MCPPVPWGLDSLPESQEKLKELLAMEDPGDTEAHPLGTANLNFVPGHQQKENPSPDPLYDTPDASRAQAGGAQQPARTVSLRERLLITRPVWLQLRANAAAALHVLRTEPPGTFLVRKSNTRQCRALCVRLPEASGPSFVSSHYIQESPGGISLEGSELVFQDLVQLICAYCHTRDILLLPLRLPRAIHQATTHKELEAISHLGMEFWSSSLNTKVQQRPCEAPPIPRLKARSPQELDQGTGAALCFFNPLFPGDLGPTKREKFKRSFKVRVSTETSSPLSPPAVPPPPVPVLPGTSSSQTARLPPRQLLERESSMGYRVPGSASGQSLPPLPSLQEADCCSPSSSEEEGSPRSPTTSPRLGRPRQRPPLLRSMSSAFCSLLAPERQVGRAATTLMQNRYTAVGQLVQDLLTQVRAGPEPRELQGIRQALSRARAMLSAELGPEKLLPPERLELVLEKSLHRSVLKPLRPILVARLRRRLSADGSLGRLAEGFHLARTQGPGALGSHLPLSYPVETEQVRQKLLQLLGTYSPTAQIKWLLQACKLLYTALKTQAGEDAGADEFLPLLSLVLAQCDLPDLLLEAEYMSELLEPTLLTGEGGYYLTSLSASLALLSGLSQARALPLSPAQELQRSLALWEQRRLPATYNFQHLLRVAYQDPSTGCTSKTLAVPPGSSIATLSQLCATKFRVTHPDAFGLFLYKDQGYHRLPPEALAHGLPATGYLIYRRAERPETQGAATEKAKAGSERQEAGAWEEEKGGGNSEGELETTVDQGGGENQARGGRVQPEEQKAEGSQAAEE", "length": 799, "header": "tr|A0A9J7FNW8-1|A0A9J7JI46_CRIGR Computationally mapped isoform of Ras and Rab interactor 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rin1 PE=3 SV=1 CANONICAL=A0A9J7JI46-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JDY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI46/entry#A0A9J7JDY1-1", "sequence": { "sequence": "MCPPVPWGLDSLPESQEKLKELLAMEDPGDTEAHPLGTANLNFVPGHQQKENPSPDPLYDTPDASRAQAGGAQQPARTVSLRERLLITRPVWLQLRANAAAALHVLRTEPPGTFLVRKSNTRQCRALCVRLPEASGPSFVSSHYIQESPGGISLEGSELVFQDLVQLICAYCHTRDILLLPLRLPRAIHQATTHKELEAISHLGMEFWSSSLNTKVQQRPCEAPPIPRLKARSPQELDQGTGAALCFFNPLFPGDLGPTKREKFKRSFKVRVSTETSSPLSPPAVPPPPVPVLPGTSSSQTARLPPRQLLERESSMGYRVPGSASGQSLPPLPSLQEADCCSPSSSEEEGSPRSPTTSPRLGRPRQRPPLLRSMSSAFCSLLAPERQVGRAATTLMQNRYTAVGQLVQDLLTQVRAGPEPRELQGIRQALSRARAMLSAELGPEKLLPPERLELVLEKSLHRSVLKPLRPILVARLRRRLSADGSLGRLAEGFHLARTQGPGALGSHLPLSYPVETEQVRQKLLQLLGTYSPTAQIKWLLQACKLLYTALKTQAGEDAGADEFLPLLSLVLAQCDLPDLLLEAEYMSELLEPTLLTGEGEGTLTSCPGGYYLTSLSASLALLSGLSQARALPLSPAQELQRSLALWEQRRLPATYNFQHLLRVAYQDPSTGCTSKTLAVPPGSSIATLSQLCATKFRVTHPDAFGLFLYKDQGYHRLPPEALAHGLPATGYLIYRRAERPETQGAATEKAKAGSESQFRDCTGDQVTREKAPMFQPFFKIRNLVRHFSISGKLDPGK", "length": 797, "header": "tr|A0A9J7JDY1-1|A0A9J7JDY1_CRIGR Computationally mapped isoform of Ras and Rab interactor 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Rin1 PE=3 SV=1 CANONICAL=A0A9J7JI46-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JI46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI46/entry#A0A9J7JI46-1", "sequence": { "sequence": "MCPPVPWGLDSLPESQEKLKELLAMEDPGDTEAHPLGTANLNFVPGHQQKENPSPDPLYDTPDASRAQAGGAQQPARTVSLRERLLITRPVWLQLRANAAAALHVLRTEPPGTFLVRKSNTRQCRALCVRLPEASGPSFVSSHYIQESPGGISLEGSELVFQDLVQLICAYCHTRDILLLPLRLPRAIHQATTHKELEAISHLGMEFWSSSLNTKVQQRPCEAPPIPRLKARSPQELDQGTGAALCFFNPLFPGDLGPTKREKFKRSFKVRVSTETSSPLSPPAVPPPPVPVLPGTSSSQTARLPPRQLLERESSMGYRVPGSASGQSLPPLPSLQEADCCSPSSSEEEGSPRSPTTSPRLGRPRQRPPLLRSMSSAFCSLLAPERQVGRAATTLMQNRYTAVGQLVQDLLTQVRAGPEPRELQGIRQALSRARAMLSAELGPEKLLPPERLELVLEKSLHRSVLKPLRPILVARLRRRLSADGSLGRLAEGFHLARTQGPGALGSHLPLSYPVETEQVRQKLLQLLGTYSPTAQIKWLLQACKLLYTALKTQAGEDAGADEFLPLLSLVLAQCDLPDLLLEAEYMSELLEPTLLTGEGEGTLTSCPGGYYLTSLSASLALLSGLSQARALPLSPAQELQRSLALWEQRRLPATYNFQHLLRVAYQDPSTGCTSKTLAVPPGSSIATLSQLCATKFRVTHPDAFGLFLYKDQGYHRLPPEALAHGLPATGYLIYRRAERPETQGAATEKAKAGSERQEAGAWEEEKGGGNSEGELETTVDQGGGENQARGGRVQPEEQKAEGSQAAEE", "length": 808, 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"XP_027278881", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278881", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G8G6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8G6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8G6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3N6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3N6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H494", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H494", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H494-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H494-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATACSSLPDRPPRTYFGRRQAQTKRQAEATKRKHQVSSGAPPAKRRNEISSLSAKETIDKETPRTFKGSAHKTFPPKTYLDSTGSGRQEKPCIKTSSLFKNNPEIPALHRAVVKQAREQVFSPEAFQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIRSTKNIHFNRIQWLVVDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHNPVSISVLDKIWDQPNPKEDASTQLDSFAIPESLDQHVVLVPSKLRLVCLAAFILQKCKFEKDQKMIVFFSSCELVEFHYSIFVHTLSCRSGAPTSEQLPSASWPLKFLRLHGNMEQEERTSVFHEFSHSGTGVLLCTTLRSCKSSKEKSGYLKFSALEALHRREDHTFLKDVAARGLDLPHVTWIVQYSAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILAVLTKDDCFKRRQRGAQKSHATGSQEIRERATVLQTVFEDYVHSSERTVSWAKKALQSFIRAYATYPRELKPIFHVRSLHLGHVAKSFGLRDAPRNLSVSTVKKKASLKRPDPRRKTRNKHHFVLAEVLHSEYSSGLEAGGTKGGKQGKQWGFQVAPSKPGPRRE", "length": 743, "header": "tr|A0A9J7GCV1-1|A0A9J7GCV1_CRIGR Isoform 1 of ATP-dependent RNA helicase OS=Cricetulus griseus OX=10029 GN=Ddx31 PE=3 SV=1 CANONICAL=A0A9J7GCV1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G8G6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1/entry#A0A9J7G8G6-1", "sequence": { "sequence": "MATACSSLPDRPPRTYFGRRQAQTKRQAEATKRKHQVSSGAPPAKRRNEISSLSAKETIDKETPRTFKGSAHKTFPPKTYLDSTGSGRQEKPCIKTSSLFKNNPEIPALHRAVVKQAREQVFSPEAFQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIRSTKNIHFNRIQWLVVDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHNPVSISVLDKIWDQPNPKEDASTQLDSFAIPESLDQHVVLVPSKLRLVCLAAFILQKCKFEKDQKMIVFFSSCELVEFHYSIFVHTLSCRSGAPTSEQLPSASWPLKFLRLHGNMEQEERTSVFHEFSHSGTGVLLCTDVAARGLDLPHVTWIVQYSAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILAVLTKDDCFKRRQRGAQKSHATGSQEIRERATVLQTVFEDYVHSSERTVSWAKKALQSFIRAYATYPRELKPIFHVRSLHLGHVAKSFGLRDAPRNLSVSTVKKKASLKRPDPRRKTRNKHHFVLAEVLHSEYSSGLEAGGTKGGKQGKQWGFQVAPSKPGPRRE", "length": 710, "header": "tr|A0A9J7G8G6-1|A0A9J7GCV1_CRIGR Computationally mapped isoform of ATP-dependent RNA helicase OS=Cricetulus griseus OX=10029 GN=Ddx31 PE=3 SV=1 CANONICAL=A0A9J7GCV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1/entry#A0A9J7GCV1-1", "sequence": { "sequence": "MATACSSLPDRPPRTYFGRRQAQTKRQAEATKRKHQVSSGAPPAKRRNEISSLSAKETIDKETPRTFKGSAHKTFPPKTYLDSTGSGRQEKPCIKTSSLFKNNPEIPALHRAVVKQAREQVFSPEAFQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIRSTKNIHFNRIQWLVVDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHNPVSISVLDKIWDQPNPKEDASTQLDSFAIPESLDQHVVLVPSKLRLVCLAAFILQKCKFEKDQKMIVFFSSCELVEFHYSIFVHTLSCRSGAPTSEQLPSASWPLKFLRLHGNMEQEERTSVFHEFSHSGTGVLLCTTLRSCKSSKEKSGYLKFSALEALHRREDHTFLKDVAARGLDLPHVTWIVQYSAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILAVLTKDDCFKRRQRGAQKSHATGSQEIRERATVLQTVFEDYVHSSERTVSWAKKALQSFIRAYATYPRELKPIFHVRSLHLGHVAKSFGLRDAPRNLSVSTVKKKASLKRPDPRRKTRNKHHFVLAEVLHSEYSSGLEAGGTKGGKQGKQWGFQVAPSKPGPRRE", "length": 743, "header": "tr|A0A9J7GCV1-1|A0A9J7GCV1_CRIGR Isoform 1 of ATP-dependent RNA helicase OS=Cricetulus griseus OX=10029 GN=Ddx31 PE=3 SV=1 CANONICAL=A0A9J7GCV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1/entry#A0A9J7H1B3-1", "sequence": { "sequence": "MSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIRSTKNIHFNRIQWLVVDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHNPVSISVLDKIWDQPNPKEDASTQLDSFAIPESLDQHVVLVPSKLRLVCLAAFILQKCKFEKDQKMIVFFSSCELVEFHYSIFVHTLSCRSGAPTSEQLPSASWPLKFLRLHGNMEQEERTSVFHEFSHSGTGVLLCTTLRSCKSSKEKSGYLKFSALEALHRREDHTFLKDVAARGLDLPHVTWIVQYSAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILAVLTKDDCFKRRQRGAQKSHATGSQEIRERATVLQTVFEDYVHSSERTVSWAKKALQSFIRAYATYPRELKPIFHVRSLHLGHVAKSFGLRDAPRNLSVSTVKKKASLKRPDPRRKTRNKHHFVLAEVLHSEYSSGLEAGGTKGGKQGKQWGFQVAPSKPGPRRE", "length": 598, "header": "tr|A0A9J7H1B3-1|A0A9J7H1B3_CRIGR Computationally mapped isoform of ATP-dependent RNA helicase OS=Cricetulus griseus OX=10029 GN=Ddx31 PE=3 SV=1 CANONICAL=A0A9J7GCV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3N6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1/entry#A0A9J7H3N6-1", "sequence": { "sequence": "MATACSSLPDRPPRTYFGRRQAQTKRQAEATKRKHQVSSGAPPAKRRNEISSLSAKETIDKETPRTFKGSAHKTFPPKTYLDSTGSGRQEKPCIKTSSLFKNNPEIPALHRAVVKQAREQVFSPEAFQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIRSTKNIHFNRIQWLVVDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHNPVSISVLDKIWDQPNPKEDASTQLDSFAIPESLDQHVVLVPSKLRLVCLAAFILQKCKDVAARGLDLPHVTWIVQYSAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILAVLTKDDCFKRRQRGAQKSHATGSQEIRERATVLQTVFEDYVHSSERTVSWAKKALQSFIRAYATYPRELKPIFHVRSLHLGHVAKSFGLRDAPRNLSVSTVKKKASLKRPDPRRKTRNKHHFVLAEVLHSEYSSGLEAGGTKGGKQGKQWGFQVAPSKPGPRRE", "length": 631, "header": "tr|A0A9J7H3N6-1|A0A9J7H3N6_CRIGR Computationally mapped isoform of ATP-dependent RNA helicase OS=Cricetulus griseus OX=10029 GN=Ddx31 PE=3 SV=1 CANONICAL=A0A9J7GCV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H494-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1/entry#A0A9J7H494-1", "sequence": { "sequence": "MATACSSLPDRPPRTYFGRRQAQTKRQAEATKRKHQVSSGAPPAKRRNEISSLSAKETIDKETPRTFKGSAHKTFPPKTYLDSTGSGRQEKPCIKTSSLFKNNPEIPALHRAVVKQAREQVFSPEAFQELDLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQALTSKIQRSDGPYALVLVPTRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIRSTKNIHFNRIQWLVVDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHNPVSISVLDKIWDQPNPKEDASTQLDSFAIPESLDQHVVLVPSKLRLVCLAAFILQKCKFEKDQKMIVFFSSCELVEFHYSIFVHTLSCRSGAPTSEQLPSASWPLKFLRLHGNMEQEDVAARGLDLPHVTWIVQYSAPSSPAEYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILAVLTKDDCFKRRQRGAQKSHATGSQEIRERATVLQTVFEDYVHSSERTVSWAKKALQSFIRAYATYPRELKPIFHVRSLHLGHVAKSFGLRDAPRNLSVSTVKKKASLKRPDPRRKTRNKHHFVLAEVLHSEYSSGLEAGGTKGGKQGKQWGFQVAPSKPGPRRE", "length": 690, "header": "tr|A0A9J7H494-1|A0A9J7H494_CRIGR Computationally mapped isoform of ATP-dependent RNA helicase OS=Cricetulus griseus OX=10029 GN=Ddx31 PE=3 SV=1 CANONICAL=A0A9J7GCV1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8G6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8G6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8G6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8G6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773757", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773757", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ], "pmid": "" }, { "name": "RNA helicase activity", "id": "GO:0003724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003724", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 568, "end_pos": 570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H6T7-1", "G3H7V9-1", "G3HCT4-1", "G3HIC5-1", "G3HIL5-1", "A0A061IR73-1", "G3GXG9-1", "G3I8R9-1", "G3HH18-1", "A0A9J7FU33-1", "G3I2I1-1", "A0A9J7FTT2-1", "G3IEZ7-1", "G3HKQ8-1", "G3HMB1-1", "G3HCV0-1", "G3HX41-1", "G3I6K0-1", "G3HTL1-1", "G3HU77-1", "G3HAH5-1", "G3HJ88-1", "G3GSH5-1", "G3GY12-1", "G3I5T3-1", "G3I6L7-1", "G3H484-1", "G3IJD1-1", "G3I008-1", "A0A8C2M596-1", "G3IG24-1", "A0A9J7F876-1", "A0A9J7FI42-1", "A0A9J7G1N4-1", "A0A061IJA4-1", "A0A9J7FPD0-1", "A0A9J7G7V8-1", "A0A9J7JQY5-1", "A0A8C2MCA5-1", "A0A9J7H2D3-1", "A0A9J7G2T1-1", "G3HBU1-1", "G3HUZ6-1", "G3HWS4-1", "A0A9J7HCU3-1", "A0A3L7HMZ7-1", "A0A9J7K3T5-1", "A0A8C2MMI4-1", "A0A9J7GRQ0-1", "A0A8C2N055-1", "A0A8C2QHV1-1", "A0A8C2QM19-1", "A0A8C2M4F5-1", "A0A9J7FJ23-1", "A0A9J7FUH6-1", "A0A9J7G659-1", "A0A9J7K2R5-1", "A0A8C2MB35-1", "G3I478-1", "A0A9J7H1K5-1", "A0A8C2QH91-1", "A0A9J7JQ85-1", "A0A9J7K381-1", "A0A061HU45-1", "A0A061I456-1", "A0A061ICN7-1", "A0A061IKS3-1", "A0A3L7H9D4-1", "A0A9J7H2L4-1", "A0A8C2LZL3-1", "A0A8C2M796-1", "A0A8C2MCS3-1", "A0A8C2MPK3-1", "A0A8C2MQ86-1", "A0A3L7ILF9-1", "A0A3L7INC4-1", "A0A8C2LCW6-1", "A0A8C2LRD7-1", "A0A8C2LSK1-1", "A0A9J7JSD0-1", "P18279-1", "P48975-1", "A0A8C2MVH8-1", "A0A8C2MWE0-1", "A0A8C2MYM8-1", "A0A8C2N236-1", "A0A9J7FYM8-1", "A0A8C2QLX9-1", "A0A8C2QNE7-1", "A0A9J7F9W3-1", "A0A9J7JR19-1", "A0A9J7FPK3-1", "A0A9J7JMF4-1", "A0A9J7FV95-1", "A0A9J7FXI2-1", "A0A9J7G412-1", "A0A9J7G5W9-1", "A0A9J7GCV1-1", "A0A9J7H3Y2-1", "A0A9J7GF88-1", "A0A9J7GHR4-1", "A0A9J7GID0-1", "A0A9J7JVX0-1", "A0A9J7KF39-1", "A0A9J7H4G1-1", "A0A9J7H9J6-1", "A0A9J7JEW1-1", "A0A9J7JIL5-1", "A0A9J7FCH5-1", "A0A8C2MFM1-1", "A0A8C2MWH4-1", "A0A8C2LG83-1", "A0A9J7GDX9-1", "A0A9J7H2C5-1", "A0A9J7GN75-1", "A0A9J7JT79-1", "A0A9J7K1D9-1", "A0A061IIX2-1", "A0A8C2M474-1", "A0A8C2N386-1", "A0A9J7GR00-1", "O35501-1", "P18708-1", "P19378-1", "P46633-1", "Q60452-1", "A0A8C2LBG1-1", "A0A8C2LR22-1", "A0A8C2M4G0-1", "A0A8C2M6G7-1", "G3HCS2-1", "P70099-1", "A0A9J7FI19-1", "A0A9J7G6M1-1", "A0A9J7FJ37-1", "A0A9J7G7R5-1", "A0A8C2MAV3-1", "A0A8C2N184-1", "A0A9J7F1E5-1", "A0A8C2MBY6-1", "A0A9J7JLC6-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HU45", "gene_name": "Ercc6l", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061HU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HU45" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A061HU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HU45" } ] } ] }, { "uniprot_ac": "A0A061I456", "gene_name": "Ruvbl2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061I456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I456" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A061I456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I456" } ] } ] }, { "uniprot_ac": "A0A061ICN7", "gene_name": "Mtrex", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061ICN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ICN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A061ICN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ICN7" } ] } ] }, { "uniprot_ac": "A0A061IIX2", "gene_name": "Ddx58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061IIX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIX2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A061IIX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIX2" } ] } ] }, { "uniprot_ac": "A0A061IJA4", "gene_name": "Dhx29", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061IJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A061IJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA4" } ] } ] }, { 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"ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8C2N236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N236" } ] } ] }, { "uniprot_ac": "A0A8C2N386", "gene_name": "Vcp", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] } ] }, { "uniprot_ac": "A0A8C2QH91", "gene_name": "Ino80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8C2QH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH91" } ] } ] }, { "uniprot_ac": "A0A8C2QHV1", "gene_name": "Ddx20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] } ] }, { "uniprot_ac": "A0A8C2QLX9", "gene_name": "Ddx52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] } ] }, { "uniprot_ac": "A0A8C2QM19", "gene_name": "Clpx", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] } ] }, { "uniprot_ac": "A0A8C2QNE7", "gene_name": "Eif4a3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] } ] }, { "uniprot_ac": "A0A9J7F1E5", "gene_name": "Hltf", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] } ] }, { "uniprot_ac": "A0A9J7F876", "gene_name": "Ddx11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] } ] }, { "uniprot_ac": "A0A9J7F9W3", "gene_name": "Zgrf1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] } ] }, { "uniprot_ac": "A0A9J7FCH5", "gene_name": "Mov10l1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] } ] }, { "uniprot_ac": "A0A9J7FI19", "gene_name": "Xrcc6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] } ] }, { "uniprot_ac": "A0A9J7FI42", "gene_name": "Fbh1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FJ37", "gene_name": "Mcm9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] } ] }, { "uniprot_ac": "A0A9J7FPD0", "gene_name": "Dhx32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] } ] }, { "uniprot_ac": "A0A9J7FPK3", "gene_name": "Twnk", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] } ] }, { "uniprot_ac": "A0A9J7FTT2", "gene_name": "Mcm5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] } ] }, { "uniprot_ac": "A0A9J7FU33", "gene_name": "Eif4a2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FU33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU33" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FU33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU33" } ] } ] }, { "uniprot_ac": "A0A9J7FUH6", "gene_name": "Polq", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] } ] }, { "uniprot_ac": "A0A9J7FV95", "gene_name": "LOC100751095", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A9J7FV95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV95" } ] } ] }, { "uniprot_ac": "A0A9J7FXI2", "gene_name": "Ddx10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] } ] }, { "uniprot_ac": "A0A9J7FYM8", "gene_name": "Ddx54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] } ] }, { "uniprot_ac": "A0A9J7G1N4", "gene_name": "Fancm", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] } ] }, { "uniprot_ac": "A0A9J7G2T1", "gene_name": "Dhx9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T1" } ] } ] }, { "uniprot_ac": "A0A9J7G412", "gene_name": "Helz2", "activity": [ { "ec_number": "3.1.13.1", "activity": "Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.1.13.1", "activity": 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griseus OX=10029 GN=Cenpx PE=3 SV=1 CANONICAL=A0A9J7GBH4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH4/entry#A0A9J7JXS3-1", "sequence": { "sequence": "MEEASGFRKELVSKLLHLHFRDCKTKVSGDALQLMAELLRIFVLAHFRVFHQKPLPAGSARPRQRTWMLWMWTSWRRCFLSCSWTSRGYTRGLQSPG", "length": 97, "header": "tr|A0A9J7JXS3-1|A0A9J7JXS3_CRIGR Computationally mapped isoform of Centromere protein X OS=Cricetulus griseus OX=10029 GN=Cenpx PE=3 SV=1 CANONICAL=A0A9J7GBH4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBD9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBD9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"database": "UniProtKB", "id": "A0A9J7GBH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JH74-1", "uniprot_ac": "A0A9J7JH74", "uniprot_id": "A0A9J7JH74_CRIGR", "mass": { "chemical_mass": 47838.0, "monoisotopic_mass": 47838.0 }, "refseq": { "ac": "XP_007645349", "name": "calcium-binding tyrosine phosphorylation-regulated protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645349" }, "gene_names": [ { "name": "Cabyr", "type": "recommended", "evidence": [ { "id": "A0A9J7JH74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74" } ] }, { "name": "Cabyr", "type": "synonym", "evidence": [ { "id": "XP_007645349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645349" } ] } ], "protein_names": [ { "name": "Calcium-binding tyrosine phosphorylation-regulated protein", "type": "recommended", "evidence": [ { "id": "A0A9J7JH74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74/entry#names_and_taxonomy" } ] }, { "name": "calcium-binding tyrosine phosphorylation-regulated protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007645349", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645349" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614266.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645349" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cabyr", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74", "locus": {} } ], "crossref": [ { "id": "cd12100", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12100", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753647", "url": "https://www.ncbi.nlm.nih.gov/gene/100753647", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038848", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038848", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753647", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753647", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CESEVLM", "url": "https://omabrowser.org/oma/group/CESEVLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JH74", "url": "https://www.orthodb.org/?gene=A0A9J7JH74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15494", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15494", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15494:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15494:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02197", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02197", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QF56", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QF56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QF56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QF56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH74-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISSKPRLVVPYGLKTLLEGVSRAILKTNPTNITQFAAVYFKELIVFREGNSSLDIKDLIKQFHQTKVEKWAEGVTVEKKECVKEQGRTFPGSCEPTRMEKSTDTEEDNVAGPLFSNKTTQFPSLHADVQSEESNEGAWGPSSKPTTPKTTTPPSSPPPAPVSAEFAYVPADPAQFAAQMLGNVQSTYSEVLMVDVATSTQDALSAEIDEEVVVSAPLVCSGEMLEMQVMSQTSVQAVVGPKCEAEPPKASSAPLQGEQEPPAYEAPDTQVTSTFHVSSVYNDVPVNEGVVYVEQIPGYIVIPIDQVACLKENEQSPPVSPKPVEARTSSGMSKISIESVKIVQVENSQRQSSVHMEAEVLLSEGQTEVPAEPLDAERLIKITSENSLHFEMEIVTIDPDNPGQEESGENSAPYSSGDPFPPAPGGFTEPDTQPDGEDEPEQV", "length": 443, "header": "tr|A0A9J7JH74-1|A0A9J7JH74_CRIGR Isoform 1 of Calcium-binding tyrosine phosphorylation-regulated protein OS=Cricetulus griseus OX=10029 GN=Cabyr PE=4 SV=1 CANONICAL=A0A9J7JH74-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QF56-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74/entry#A0A8C2QF56-1", "sequence": { "sequence": "MISSKPRLVVPYGLKTLLEGVSRAILKTNPTNITQFAAVYFKELIVFREGNSSLDIKDLIKQFHQTKVEKWAEGVTVEKKECVKEQGRTFPGSCEPTRMEKSTDTEEDNVAGPLFSNKTTQFPSLHADVQSEESNEGAWGPSSKPTTPKTTTPPSSPPPAPVSAEFAYVPADPAQFAAQMLALATSEAGQPPPYSNMWTLYCLTDMNQQSRPSPPPALGPFPQATLYLPNPKDPQFLQNPPKVTSPTYVMMDDSKKTSAPPFILVGSNVQEAQDWKPLSGHAVVSQSDALKRYATVQVPIAVPADQTFQRPAPNPQNASPPTSGQDGPRPKSPVFLSVAFPVEDVAKKSSGSGDKRTPFGSYGIAGEITVTTAHVRRAEP", "length": 380, "header": "tr|A0A8C2QF56-1|A0A9J7JH74_CRIGR Computationally mapped isoform of Calcium-binding tyrosine phosphorylation-regulated protein OS=Cricetulus griseus OX=10029 GN=Cabyr PE=4 SV=1 CANONICAL=A0A9J7JH74-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JH74-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74/entry#A0A9J7JH74-1", "sequence": { "sequence": "MISSKPRLVVPYGLKTLLEGVSRAILKTNPTNITQFAAVYFKELIVFREGNSSLDIKDLIKQFHQTKVEKWAEGVTVEKKECVKEQGRTFPGSCEPTRMEKSTDTEEDNVAGPLFSNKTTQFPSLHADVQSEESNEGAWGPSSKPTTPKTTTPPSSPPPAPVSAEFAYVPADPAQFAAQMLGNVQSTYSEVLMVDVATSTQDALSAEIDEEVVVSAPLVCSGEMLEMQVMSQTSVQAVVGPKCEAEPPKASSAPLQGEQEPPAYEAPDTQVTSTFHVSSVYNDVPVNEGVVYVEQIPGYIVIPIDQVACLKENEQSPPVSPKPVEARTSSGMSKISIESVKIVQVENSQRQSSVHMEAEVLLSEGQTEVPAEPLDAERLIKITSENSLHFEMEIVTIDPDNPGQEESGENSAPYSSGDPFPPAPGGFTEPDTQPDGEDEPEQV", "length": 443, "header": "tr|A0A9J7JH74-1|A0A9J7JH74_CRIGR Isoform 1 of Calcium-binding tyrosine phosphorylation-regulated protein OS=Cricetulus griseus OX=10029 GN=Cabyr PE=4 SV=1 CANONICAL=A0A9J7JH74-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QF56", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QF56" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QF56", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QF56" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753647", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753647", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R8P3-1", "protein_name": "Calcium-binding tyrosine phosphorylation-regulated protein", "gene_name": "Cabyr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MISSKPRLVVPYGLKTLLEGVSRAILKTNPTNITQFAAVYFKELIVFREGNSSLDIKDLIKQFHQMKVERWAEGVTVEKKEGTKEPIKTTTIFCEPTRMEKSTDTEEDNVAGPLFSNKTTQFPSVHAELQPEETCEGAWGPSDKPTTPKMATPPSSPPPAPVSAEYAYVPADPAQFAAQMLGNVPPTYSEVLMVDVATSTPAVSQDVLSAEFAEEVVVSAPLVCSGEKVQVQVVSQTSAQVVVGPNSKAEPPKASSAPLQGEQEPPAYDGAPDTQVTSASRISSIFNDVPVNEGVVYVEQIPGYLVIPFPDQVACPKEIEQSPPRSPKPVEPKTKISVESLKIVQVENSQHKPSVHMEAGATVLLSNTALEGQPEDAEGFLKVASETEIVIINPDDPGQE", "length": 400 }, "evidence": [ { "id": "A0A9J7JH74", "url": "https://omabrowser.org/oma/group/A0A9J7JH74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74" } ], "pmid": "" }, { "name": "sperm fibrous sheath", "id": "GO:0035686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035686", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sperm capacitation", "id": "GO:0048240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048240", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH74", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JH74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH74" }, { "id": "SM00394", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00394" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RIIa", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 49, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GC99-1", "uniprot_ac": "A0A9J7GC99", "uniprot_id": "A0A9J7GC99_CRIGR", "mass": { "chemical_mass": 37089.0, "monoisotopic_mass": 37089.0 }, "refseq": { "ac": "XP_016832214", "name": "deoxynucleotidyltransferase terminal-interacting protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832214" }, "gene_names": [ { "name": "Dnttip1", "type": "recommended", "evidence": [ { "id": "A0A9J7GC99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99" } ] }, { "name": "Dnttip1", "type": "synonym", "evidence": [ { "id": "XP_016832214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832214" } ] } ], "protein_names": [ { "name": "Deoxynucleotidyltransferase terminal-interacting protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7GC99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99/entry#names_and_taxonomy" } ] }, { "name": "Terminal deoxynucleotidyltransferase-interacting factor 1", "type": "synonym", "evidence": [ { "id": "A0A9J7GC99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99/entry#names_and_taxonomy" } ] }, { "name": "deoxynucleotidyltransferase terminal-interacting protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016832214", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832214" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 173 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614077.1) and transcript sequence (IACG01090091.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016832214.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016832214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832214" } ] }, { "annotation": "Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QG93", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QG93#function" }, { "database": "UniProtKB", "id": "ARBA00045675", "url": "https://www.uniprot.org/uniprotkb/ARBA00045675#function" }, { "database": "UniProtKB", "id": "A0A9J7GAQ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ5#function" }, { "database": "UniProtKB", "id": "A0A9J7GC99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dnttip1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99", "locus": {} } ], "crossref": [ { "id": "A0A9J7GC99", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GC99", "database": "AlphaFoldDB", "categories": [] }, { "id": "100769006", "url": "https://www.ncbi.nlm.nih.gov/gene/100769006", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769006", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769006", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GC99", "url": "https://www.orthodb.org/?gene=A0A9J7GC99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23399:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23399:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18192", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18192", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016832214", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832214", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QG93", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QG93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QG93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QG93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAQ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGATGDTEQPRGPGVAERGGLELGDAGAAGQPVLTNPWNIMIKHRQVQRRGRRSQMTTSFTDPAISMDLLRAVLQPSINEEIQSVFNKYMKFFQKAALNVRDNVGEEVDAEQLIQEACRSCLEQAKLLFSDGEKVIPRLTHELPGIKRGRQAEEESHRGSPIPKKRKGRPPGHVLSNDRAAAGMVRWKPKSCEPIRREGPKWDPARLNESTTFVLGSRANKALGMGGTRGRIYIKHPHLFKYAADPQDKHWLAEQHHMRATGGKMAYLLIEEDIRDLAASDDYRGCLDLKLEELKSFVLPPWMVEKMRKYMETLRTENEHRAAEAPPQT", "length": 329, "header": "tr|A0A9J7GC99-1|A0A9J7GC99_CRIGR Isoform 1 of Deoxynucleotidyltransferase terminal-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Dnttip1 PE=4 SV=1 CANONICAL=A0A9J7GC99-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QG93-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99/entry#A0A8C2QG93-1", "sequence": { "sequence": "MGATGDTEQPRGPGVAERGGLELGDAGAAGQPVLTNPWNIMIKHRQVQRRGRRSQMTTSFTDPAISMDLLRAVLQPSINEEIQSVFNKYMKFFQKAALNVRDNVGEEVDAEQLIQEACRSCLEQAKLLFSDGEKVIPRLTHELPGIKRGRQAEEESHRGSPIPKKRKGRPPGHVLSNDRAAAGMVWKPKSCEPIRREGPKWDPARLNESTTFVLGSRANKALGMGGTRGRIYIKHPHLFKYAADPQDKHWLAEQHHMRATGGKMAYLLIEEDIRDLAASDDYRGCLDLKLEELKSFVLPPWMVEKMRKYMETLRTENEHRAAEAPPQT", "length": 328, "header": "tr|A0A8C2QG93-1|A0A9J7GC99_CRIGR Computationally mapped isoform of Deoxynucleotidyltransferase terminal-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Dnttip1 PE=4 SV=1 CANONICAL=A0A9J7GC99-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99/entry#A0A9J7GAQ5-1", "sequence": { "sequence": "MGATGDTEQPRGPGVAERGGLELGDAGAAGQPVLTNPWNIMIKHRQVQRRGRRSQMTTSFTDPAISMDLLRAVLQPSINEEIQSVFNKYMKFFQKAALNVRDNVGEEVDAEQLIQEACRSCLEQAKLLFSDGEKVIPRLTHELPGIKRGRQAEEESHRGSPIPKKRKGRPPGHVLSNDRAAAGMVRWKPKSCEPIRREGPKWDPARLNESTTFVLGSRANKALGMGGTRGRIYIKHPHLFKAYLLIEEDIRDLAASDDYRGCLDLKLEELKSFVLPPWMVEKMRKYMETLRTENEHRAAEAPPQT", "length": 305, "header": "tr|A0A9J7GAQ5-1|A0A9J7GC99_CRIGR Computationally mapped isoform of Deoxynucleotidyltransferase terminal-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Dnttip1 PE=4 SV=1 CANONICAL=A0A9J7GC99-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GC99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC99/entry#A0A9J7GC99-1", "sequence": { "sequence": "MGATGDTEQPRGPGVAERGGLELGDAGAAGQPVLTNPWNIMIKHRQVQRRGRRSQMTTSFTDPAISMDLLRAVLQPSINEEIQSVFNKYMKFFQKAALNVRDNVGEEVDAEQLIQEACRSCLEQAKLLFSDGEKVIPRLTHELPGIKRGRQAEEESHRGSPIPKKRKGRPPGHVLSNDRAAAGMVRWKPKSCEPIRREGPKWDPARLNESTTFVLGSRANKALGMGGTRGRIYIKHPHLFKYAADPQDKHWLAEQHHMRATGGKMAYLLIEEDIRDLAASDDYRGCLDLKLEELKSFVLPPWMVEKMRKYMETLRTENEHRAAEAPPQT", "length": 329, "header": "tr|A0A9J7GC99-1|A0A9J7GC99_CRIGR Isoform 1 of Deoxynucleotidyltransferase terminal-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Dnttip1 PE=4 SV=1 CANONICAL=A0A9J7GC99-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QG93", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QG93" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262557" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lipk", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU8", "locus": {} } ], "crossref": [ { "id": "A0A9J7JIU8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JIU8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100757999", "url": "https://www.ncbi.nlm.nih.gov/gene/100757999", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", 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"MWWLLAAAWCVLLPGPMCGYKQGSITNPEANMNIVIPFQSQLISYWGYPYEKYDVVTEDGYILGIYRIPHGKGCSRKTVPKAVVYLQHGLVASAINWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLRLSPKSPQYWAFSLDEMAKYDLPATINLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIKLFFALAPVVTVKYTRSPMKTLTTLSRQAVKVLFGDKMFSSHTLLEHFVATKVCSRKIFHPICSNFMFSLSGFDRQNLNMSRLDVYMAHSQAGTSVQNMLHWAQAVNSGKLQAFDWGSPNQNMMHFNQLTPPVYNITKMQVPTAMWSGGQDVVADAKDTENLLPKVTNLIYYKEIPHYNHLDFYLGQDAPWEVYQDLIRMLEEYLQN", "length": 403, "header": "tr|A0A9J7JIU8-1|A0A9J7JIU8_CRIGR Isoform 1 of Lipase OS=Cricetulus griseus OX=10029 GN=Lipk PE=3 SV=1 CANONICAL=A0A9J7JIU8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QK06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QK06" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QK06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QK06" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757999", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757999", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MMN8-1", "protein_name": "Lipase", "gene_name": "LIPK", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWQLLAATCWMLLLGPVFGYHKKGCTTNPEATMNISQIISYWGYPYEIYDVVTEDGYILGTYRIPHGRGCPKTAPKPVVYLQHGLVASASNWICNLPNNSLAFLLADVGYDVWLGNSRGNTWSRKHLKFSPKSPEYWAFSLDEMAKYDLPATINFIIEKTRQEQLYYVGHSQGTTIAFIAFSTNPELAKRIKIFFALAPVTTLKYTQSPMKKLTNLSRKAVKVLFGDKMFSPHTFFEQFIATKVCNRKIFRRICSNFIFTLSGFDPKNLNMSRLDVYFAQSSAGTSVQTMLHWAQAVNSGRFQAFDWGNPDQNMKHFHQLTPPLYNVSNMEVPTAVWSGGQDYVADLKDVENLLPKIPKLIYYKSIPHYNHVDFYLGQDAPLEIYQDLIRMMEEWL", "length": 396 }, "evidence": [ { "id": "A0A9J7JIU8", "url": "https://omabrowser.org/oma/group/A0A9J7JIU8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A9L7-1", "protein_name": "Lipase", "gene_name": "Lipk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWLLATCCMFLPGPIYGHMQESITNPEANMNISEIISYWGYPYERHDVVTEDGYILGTYRIPHGKGCSRKAVPKAVVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLRLSPKSPEYWAFSLDEMAKYDLPATINLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRMFFALAPVVTVKYTQSPMKKLTTLSRKAVKILFGDKMFSTHTWLEQFIATKVCNRKLFRQLCSNFLFSLSGFDPQNLNMSRLDVYMAQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSGGRDVVADEKDTKNLLPKVANLIYYKEIPHYNHMDFYLGQDAPQEVYRDLITMMEESLQN", "length": 397 }, "evidence": [ { "id": "A0A9J7JIU8", "url": "https://omabrowser.org/oma/group/A0A9J7JIU8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5VXJ0-1", "protein_name": "Lipase member K", "gene_name": "LIPK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWQLLAAACWMLLLGSMYGYDKKGNNANPEANMNISQIISYWGYPYEEYDVTTKDGYILGIYRIPHGRGCPGRTAPKPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLKLSPKSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFIAFSTNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFGDKMFHPHTLFDQFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAVNSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQIANLIYYKLIPHYNHVDFYLGEDAPQEIYQDLIILMEEYLQN", "length": 399 }, "evidence": [ { "id": "A0A9J7JIU8", "url": "https://omabrowser.org/oma/group/A0A9J7JIU8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BM14-1", "protein_name": "Lipase member K", "gene_name": "Lipk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWWLLATTCCVLLSGPIDGYKQESITNPEANMNISELISYWGYPYEKHDVITEDGYILGTYRIPHGKGCSRKTAPKAVVYLQHGLIASANNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRNHLRLSPKSPQYWAFSWDEMAKYDLPATVNLILEKSGQKQLFYVGHSQGTTIAFIAFSTNPELAKKIRLFFALAPVATVKYTRSPMKKLTTLSRKAVKVLFGDKMFSTHTWFEQFIATKVCNRKLFHQLCSNFLFSLSGFDPQNLNMSRLDVYLSQSPAGTSVQNMLHWAQAVNSGQLQAFDWGNPDQNMMHFNQLTPPVYNISKMRVPTAMWSGGQDVVADAKDTKNLLPKIANLIYYKEIPHYNHMDFYLGQDAPQEVYGDLIRMIEESLQN", "length": 398 }, "evidence": [ { "id": "A0A9J7JIU8", "url": "https://omabrowser.org/oma/group/A0A9J7JIU8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity, acting on ester bonds", "id": "GO:0016788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016788", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JIU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU8" }, { "id": "PF00561", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AB hydrolase-1", "eco_id": "ECO_0000259", "start_pos": 83, "end_pos": 382, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 275, "end_pos": 277 }, { "start_pos": 331, "end_pos": 333 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JJY7-1", "uniprot_ac": "A0A9J7JJY7", "uniprot_id": "A0A9J7JJY7_CRIGR", "mass": { "chemical_mass": 36238.0, "monoisotopic_mass": 36238.0 }, "refseq": { "ac": "XP_007650007", "name": "ADP-ribose glycohydrolase MACROD1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650007" }, "gene_names": [ { "name": "Macrod1", "type": "recommended", "evidence": [ { "id": "A0A9J7JJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJY7" } ] }, { "name": "Macrod1", "type": "synonym", "evidence": [ { "id": "XP_007650007", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650007" } ] } ], "protein_names": [ { "name": "ADP-ribose glycohydrolase MACROD1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007650007", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650007" } ] }, { "name": "ADP-ribose glycohydrolase MACROD1 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7JJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJY7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 278 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615068.1) and transcript sequence (IACG01039407.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007650007.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007650007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650007" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJY7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Macrod1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJY7", "locus": {} } ], "crossref": [ { "id": "A0A9J7JJY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JJY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02908", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02908", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759258", "url": "https://www.ncbi.nlm.nih.gov/gene/100759258", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759258", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759258", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JJY7", "url": "https://www.orthodb.org/?gene=A0A9J7JJY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11106:SF93", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11106:SF93", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007650007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650007", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "54428", "url": "https://www.rhea-db.org/rhea/54428", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "58248", "url": "https://www.rhea-db.org/rhea/58248", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "68792", "url": "https://www.rhea-db.org/rhea/68792", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2QN76", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QN76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QN76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QN76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FN86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FN86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLQSQVSGRLAQLRAAGQLLVAPRPWPGRSAGGPRPRGSACGPPAALGAHSHCACPSAGVGAWGVAGRGAWVRTWAPLAMAAKVDLSTSTDWKEAKTFLKGLSDKQREEHYFCRDFIKLKKIPTWKETAKGVAVKVEDPKYKKDKQLNEKISLFRGDITKLEVDAIVNAANNSLLGGGGVDGCIHRAAGPLLTDECRTLHNCETGKAKITCGYRLPAKYVIHTVGPIAVGQPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPNEEAAEVVLAALRGWLEQHKDKVDRLIICVFLEKDEDIYRERLPHYFPVDPPGPVGPRSQL", "length": 334, "header": "tr|A0A9J7JJY7-1|A0A9J7JJY7_CRIGR Isoform 1 of ADP-ribose glycohydrolase MACROD1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Macrod1 PE=3 SV=1 CANONICAL=A0A9J7JJY7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QN76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJY7/entry#A0A8C2QN76-1", "sequence": { "sequence": "MSLQSQVSGRLAQLRAAGQLLVAPRPWPGRSAGGPRPRGSACGPPAALGAHSHCACPSAGVGAWGVAGRGAWVRTWAPLAMAAKVDLSTSTDWKEAKTFLKGLSDKQREEHYFCRDFIKLKKIPTWKETAKGVAVKVEDPKYKKDKQLNEKISLFRGDITKLEVDAIVNAANNSLLGGGGVDGCIHRAAGPLLTDECRTLHNCETGKAKITCGYRLPAKYVIHTVGPIAVGQPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPNEEAAEVVLAALRGWLEQHKDKVDRLIICVFLEKDEDIYRERLPHYFPVA", "length": 323, "header": "tr|A0A8C2QN76-1|A0A9J7JJY7_CRIGR Computationally mapped isoform of ADP-ribose glycohydrolase MACROD1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Macrod1 PE=3 SV=1 CANONICAL=A0A9J7JJY7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FN86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJY7/entry#A0A9J7FN86-1", "sequence": { "sequence": "MSLQSQVSGRLAQLRAAGQLLVAPRPWPGRSAGGPRPRGSACGPPAALGAHSHCACPSAGVGAWGVAGRGAWVRTWAPLAMAAKVDLSTSTDWKEAKTFLKGLSDKQREEHYFCRDFIKLKKIPTWKETAKGVAVKVEDPKYKKDKQLNEKISLFRGDITKLEVDAIVNAVDGCIHRAAGPLLTDECRTLHNCETGKAKITCGYRLPAKYVIHTVGPIAVGQPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPNEEAAEVVLAALRGWLEQHKDKVDRLIICVFLEKDEDIYRERLPHYFPVDPPGPVGPRSQL", "length": 324, "header": "tr|A0A9J7FN86-1|A0A9J7JJY7_CRIGR Computationally mapped isoform of ADP-ribose glycohydrolase MACROD1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Macrod1 PE=3 SV=1 CANONICAL=A0A9J7JJY7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJY7/entry#A0A9J7JJY7-1", "sequence": { "sequence": "MSLQSQVSGRLAQLRAAGQLLVAPRPWPGRSAGGPRPRGSACGPPAALGAHSHCACPSAGVGAWGVAGRGAWVRTWAPLAMAAKVDLSTSTDWKEAKTFLKGLSDKQREEHYFCRDFIKLKKIPTWKETAKGVAVKVEDPKYKKDKQLNEKISLFRGDITKLEVDAIVNAANNSLLGGGGVDGCIHRAAGPLLTDECRTLHNCETGKAKITCGYRLPAKYVIHTVGPIAVGQPSASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPNEEAAEVVLAALRGWLEQHKDKVDRLIICVFLEKDEDIYRERLPHYFPVDPPGPVGPRSQL", "length": 334, "header": "tr|A0A9J7JJY7-1|A0A9J7JJY7_CRIGR Isoform 1 of ADP-ribose glycohydrolase MACROD1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Macrod1 PE=3 SV=1 CANONICAL=A0A9J7JJY7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QN76", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QN76" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QN76", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QN76" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759258", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759258", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJY7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JJK8-1", "uniprot_ac": "A0A9J7JJK8", "uniprot_id": "A0A9J7JJK8_CRIGR", "mass": { "chemical_mass": 33444.0, "monoisotopic_mass": 33444.0 }, "refseq": { "ac": "XP_027260659", "name": "AKT-interacting protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260659" }, "gene_names": [ { "name": "Aktip", "type": "recommended", "evidence": [ { "id": "A0A9J7JJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8" } ] }, { "name": "Aktip", "type": "synonym", "evidence": [ { "id": "XP_027260659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260659" } ] } ], "protein_names": [ { "name": "AKT-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A9J7JJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8/entry#names_and_taxonomy" } ] }, { "name": "AKT-interacting protein isoform X1", 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This record is derived from a genomic sequence (NW_003613676.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260659" } ] }, { "annotation": "Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade. FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QPF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPF1#function" }, { "database": "UniProtKB", "id": "ARBA00046014", "url": "https://www.uniprot.org/uniprotkb/ARBA00046014#function" }, { "database": "UniProtKB", "id": "A0A9J7FMA1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMA1#function" }, { "database": "UniProtKB", "id": "A0A9J7JJK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Aktip", "url": 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"Protein" ] }, { "id": "A0A8C2QPF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FMA1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FMA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPLWSMSASSVRKRAEGEEKTLAGDVKNSPPRTAPKKQLPSIPKNALPITKPTSPAPAAQSTNGTHASYGPFYLEYSLLAELICSTLVVKQKLPGVYIQPSYRSALVWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGDCPRLLFDIPVFHPLVDSTTGELDVKRAFAKWRRNHNHIWQVLMYARRVFYKIDTTSPLNPEAAVLYEKDIQLFKSKVVDSVKVCTARLFDQPKIEDPYAISFSPWNPSVHDEAREKMLTQKKKPDEQHNKSVHVAGLSWVKPGSVQPFSKEEKTVAT", "length": 296, "header": "tr|A0A9J7JJK8-1|A0A9J7JJK8_CRIGR Isoform 1 of AKT-interacting protein OS=Cricetulus griseus OX=10029 GN=Aktip PE=4 SV=1 CANONICAL=A0A9J7JJK8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QPF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8/entry#A0A8C2QPF1-1", "sequence": { "sequence": "MNPLWSMSASSVRKRAEGEEKTLAGDVKNSPPRTAPKKQLPSIPKNALPITKPTSPAPAAQSTNGTHASYGPFYLEYSLLAEFTLVVKQKLPGVYIQPSYRSALVWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGDCPRLLFDIPVFHPLVDSTTGELDVKRAFAKWRRNHNHIWQVLMYARRVFYKIDTTSPLNPEAAVLYEKDIQLFKSKVVDSVKVCTARLFDQPKIEDPYAISFSPWNPSVHDEAREKMLTQKKPDEQHNKSVHVAGLSWVKPGSVQPFSKEEKTVAT", "length": 292, "header": "tr|A0A8C2QPF1-1|A0A9J7JJK8_CRIGR Computationally mapped 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"MNPLWSMSASSVRKRAEGEEKTLAGDVKNSPPRTAPKKQLPSIPKNALPITKPTSPAPAAQSTNGTHASYGPFYLEYSLLAELICSTLVVKQKLPGVYIQPSYRSALVWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGDCPRLLFDIPVFHPLVDSTTGELDVKRAFAKWRRNHNHIWQVLMYARRVFYKIDTTSPLNPEAAVLYEKDIQLFKSKVVDSVKVCTARLFDQPKIEDPYAISFSPWNPSVHDEAREKMLTQKKKPDEQHNKSVHVAGLSWVKPGSVQPFSKEEKTVAT", "length": 296, "header": "tr|A0A9J7JJK8-1|A0A9J7JJK8_CRIGR Isoform 1 of AKT-interacting protein OS=Cricetulus griseus OX=10029 GN=Aktip PE=4 SV=1 CANONICAL=A0A9J7JJK8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QPF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPF1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2QPF1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPF1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770507", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770507", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JJK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJK8" }, { "id": "PS50127", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50127" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBC core", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 225, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 }, { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JGX3-1", "uniprot_ac": "A0A9J7JGX3", "uniprot_id": "A0A9J7JGX3_CRIGR", "mass": { "chemical_mass": 81865.0, "monoisotopic_mass": 81865.0 }, "refseq": { "ac": "XP_027259202", "name": "origin recognition complex subunit 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259202" }, "gene_names": [ { "name": "Orc3", "type": "recommended", "evidence": [ { "id": "A0A9J7JGX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3" } ] }, { "name": "Orc3", "type": "synonym", "evidence": [ { "id": "XP_027259202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259202" } ] } ], "protein_names": [ { "name": "Origin recognition complex subunit 3", "type": "recommended", "evidence": [ { "id": "A0A9J7JGX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3/entry#names_and_taxonomy" } ] }, { "name": "origin recognition complex subunit 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027259202", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259202" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259202" } ] }, { "annotation": "Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FFR5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFR5#function" }, { "database": "UniProtKB", "id": "ARBA00045241", "url": "https://www.uniprot.org/uniprotkb/ARBA00045241#function" }, { "database": "UniProtKB", "id": "A0A9J7JGX3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3#function" }, { "database": "UniProtKB", "id": "A0A8C2MYL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYL4#function" }, { "database": "UniProtKB", "id": "A0A9J7GQK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQK0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGX3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Orc3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3", "locus": {} } ], "crossref": [ { "id": "A0A9J7JGX3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JGX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20704", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20704", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768718", "url": "https://www.ncbi.nlm.nih.gov/gene/100768718", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045667", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045667", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768718", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768718", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JGX3", "url": "https://www.orthodb.org/?gene=A0A9J7JGX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12748", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12748", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12748:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12748:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027259202", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259202", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FFR5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FFR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GQK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGX3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATSSVSKGCFVFKPDFKKRKISVPIEDYFKNEKLESEDSKLRFETYHLLWQRMKSETEQLQEELNKNLFDSLIDFLQKSHSDFQKNSGNWGCQMKLREIPTAALILGVNVTDHDLIFRSLTETLQNNVTPYIVSLQAKDCPDVKHFLQKLTSQLMDCCVDGKSKEVKSVKTPKKTNYSMDSLSSWYMTVAQATGPKMTIKKRTTSSQWQFPPVVIILKNMESFSTKVLQDFIIISSQHRHEFPLILIFGIATSPVIIHRLLPHAVSSLLCIELFQSLSCKEHLAVILDQLLLTAQFPFKISKKALQVLTNIFLYHDFSIQNFIKGLKLSLLEHFYLQPLSVLCCDLPEAKKRIKFLSVNQCENIRRLPSFRRYVEKQASGKQVALLTNDTVLKEETQLLLEDLHVYHMNYFLVLRCLHNFTSCLPKYPLGRQIRELYCTCLENNVWDSEEYASALQLLRMLAKDELMSILQKCFEVLHSSTTKQLGSTTQKVKDFLTQFQNLDADSKEEEDACGSQSKGLQKTDLYHLQKSLLEMKELRRTTKKQTKFEMLRENVVNFMDNLVRSYLLPPESQPLHEVVYFSAAHTLREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKDANSTISEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC", "length": 711, "header": "tr|A0A9J7JGX3-1|A0A9J7JGX3_CRIGR Isoform 1 of Origin recognition complex subunit 3 OS=Cricetulus griseus OX=10029 GN=Orc3 PE=3 SV=1 CANONICAL=A0A9J7JGX3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3/entry#A0A8C2MYL4-1", "sequence": { "sequence": "MATSSVSKGCFVFKPDFKKRKISVPIEDYFKNEKLESEDSKLRFETYHLLWQRMKSETEQLQEELNKNLFDSLIDFLQKSHSDFQKNSGNWGCQMKLREIPTAALILGVNVTDHDLIFRSLTETLQNNVTPYIVSLQAKDCPDVKHFLQKLTSQLMDCCVDGKSKEVKSVKTPKKTNYSMDSLSSWYMTVAQATGPKMTIKKRTTSSQWQFPPVVIILKNMESFSTKVLQDFIIISSQHRHEFPLILIFGIATSPVIIHRLLPHAVSSLLCIELFQSLSCKEHLAVILDQLLLTAQFPFKISKKALQVLTNIFLYHDFSIQNFIKGLKLSLLEHFYLQPLSVLCCDLPEAKKRIKFLSVNQCENIRRLPSFRRYVEKQASGKQVALLTNDTVLKEETQLLLEDLHVYHMNYFLVLRCLHNFTSCLPKYPLGRQIRELYCTCLENNVWDSEEYASALQLLRMLAKDELMSILQKCFEVLHSSTTKQLGSTTQKVKDFLTQFQNLDDSKEEEDACGSQSKGLQKTDLYHLQKSLLEMKELRRTTKKQTKFEMLRENVVNFMDNLVRSYLLPPESQPLHEVVYFSAAHTLREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKDANSTISEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC", "length": 710, "header": "tr|A0A8C2MYL4-1|A0A8C2MYL4_CRIGR Computationally mapped isoform of Origin recognition complex subunit 3 OS=Cricetulus griseus OX=10029 GN=Orc3 PE=3 SV=1 CANONICAL=A0A9J7JGX3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FFR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3/entry#A0A9J7FFR5-1", "sequence": { "sequence": "MATDEIRNRGVNVTDHDLIFRSLTETLQNNVTPYIVSLQAKDCPDVKHFLQKLTSQLMDCCVDGKSKEVKSVKTPKKTNYSMDSLSSWYMTVAQATGPKMTIKKRTTSSQWQFPPVVIILKNMESFSTKVLQDFIIISSQHRHEFPLILIFGIATSPVIIHRLLPHAVSSLLCIELFQSLSCKEHLAVILDQLLLTAQFPFKISKKALQVLTNIFLYHDFSIQNFIKGLKLSLLEHFYLQPLSVLCCDLPEAKKRIKFLSVNQCENIRRLPSFRRYVEKQASGKQVALLTNDTVLKEETQLLLEDLHVYHMNYFLVLRCLHNFTSCLPKYPLGRQIRELYCTCLENNVWDSEEYASALQLLRMLAKDELMSILQKCFEVLHSSTTKQLGSTTQKVKDFLTQFQNLDADSKEEEDACGSQSKGLQKTDLYHLQKSLLEMKELRRTTKKQTKFEMLRENVVNFMDNLVRSYLLPPESQPLHEVVYFSAAHTLREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKDANSTISEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC", "length": 613, "header": "tr|A0A9J7FFR5-1|A0A9J7JGX3_CRIGR Computationally mapped isoform of Origin recognition complex subunit 3 OS=Cricetulus griseus OX=10029 GN=Orc3 PE=3 SV=1 CANONICAL=A0A9J7JGX3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3/entry#A0A9J7GQK0-1", "sequence": { "sequence": "MKSETEQLQEELNKNLFDSLIDFLQKSHSDFQKNSGNWGCQMKLREIPTAALILGVNVTDHDLIFRSLTETLQNNVTPYIVSLQAKDCPDVKHFLQKLTSQLMDCCVDGKSKEVKSVKTPKKTNYSMDSLSSWYMTVAQATGPKMTIKKRTTSSQWQFPPVVIILKNMESFSTKVLQDFIIISSQHRHEFPLILIFGIATSPVIIHRLLPHAVSSLLCIELFQSLSCKEHLAVILDQLLLTAQFPFKISKKALQVLTNIFLYHDFSIQNFIKGLKLSLLEHFYLQPLSVLCCDLPEAKKRIKFLSVNQCENIRRLPSFRRYVEKQASGKQVALLTNDTVLKEETQLLLEDLHVYHMNYFLVLRCLHNFTSCLPKYPLGRQIRELYCTCLENNVWDSEEYASALQLLRMLAKDELMSILQKCFEVLHSSTTKQLGSTTQKVKDFLTQFQNLDADSKEEEDACGSQSKGLQKTDLYHLQKSLLEMKELRRTTKKQTKFEMLRENVVNFMDNLVRSYLLPPESQPLHEVVYFSAAHTLREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKDANSTISEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC", "length": 658, "header": "tr|A0A9J7GQK0-1|A0A9J7GQK0_CRIGR Computationally mapped isoform of Origin recognition complex subunit 3 OS=Cricetulus griseus OX=10029 GN=Orc3 PE=3 SV=1 CANONICAL=A0A9J7JGX3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JGX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX3/entry#A0A9J7JGX3-1", "sequence": { "sequence": "MATSSVSKGCFVFKPDFKKRKISVPIEDYFKNEKLESEDSKLRFETYHLLWQRMKSETEQLQEELNKNLFDSLIDFLQKSHSDFQKNSGNWGCQMKLREIPTAALILGVNVTDHDLIFRSLTETLQNNVTPYIVSLQAKDCPDVKHFLQKLTSQLMDCCVDGKSKEVKSVKTPKKTNYSMDSLSSWYMTVAQATGPKMTIKKRTTSSQWQFPPVVIILKNMESFSTKVLQDFIIISSQHRHEFPLILIFGIATSPVIIHRLLPHAVSSLLCIELFQSLSCKEHLAVILDQLLLTAQFPFKISKKALQVLTNIFLYHDFSIQNFIKGLKLSLLEHFYLQPLSVLCCDLPEAKKRIKFLSVNQCENIRRLPSFRRYVEKQASGKQVALLTNDTVLKEETQLLLEDLHVYHMNYFLVLRCLHNFTSCLPKYPLGRQIRELYCTCLENNVWDSEEYASALQLLRMLAKDELMSILQKCFEVLHSSTTKQLGSTTQKVKDFLTQFQNLDADSKEEEDACGSQSKGLQKTDLYHLQKSLLEMKELRRTTKKQTKFEMLRENVVNFMDNLVRSYLLPPESQPLHEVVYFSAAHTLREHLNAAPRIALHTALNNPYYYLKNEALKSEEGCIPNIAPDICIAYKLHLECSRLINLVDWSEAFATVVTAAEKDANSTISEEMNEIIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC", "length": 711, "header": "tr|A0A9J7JGX3-1|A0A9J7JGX3_CRIGR Isoform 1 of Origin recognition complex subunit 3 OS=Cricetulus griseus OX=10029 GN=Orc3 PE=3 SV=1 CANONICAL=A0A9J7JGX3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FFR5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFR5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FGF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FGF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764362", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764362", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGM2" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGM2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGM2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGM2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGM2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGM2" } ], 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Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259753", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259753" } ] }, { "annotation": "Scaffold protein that plays an important role in mediating the activation of NF-kappa-B via BCL10 or EGFR.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FH14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH14#function" }, { "database": "UniProtKB", "id": "ARBA00056468", "url": "https://www.uniprot.org/uniprotkb/ARBA00056468#function" }, { "database": "UniProtKB", "id": "A0A9J7JHA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6#function" }, { "database": "UniProtKB", "id": "A0A9J7K5M6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5M6#function" }, { "database": "UniProtKB", "id": "A0A8C2N523", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N523#function" }, { "database": "UniProtKB", "id": "A0A9J7GPP4", "url": 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"AlphaFoldDB", "categories": [] }, { "id": "cd08807", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08807", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762588", "url": "https://www.ncbi.nlm.nih.gov/gene/100762588", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762588", "url": 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"MWGGSGGRGAGGGANDPEGTAPSRRRSRRPSTEPAAQGSCGARDSEDAAMQGRADAGEADEEAGAGSGSEAEEDALWERIEGVRHRLTRALNPAKLTPYLRQCRVLDEQDEEEVLSTYRFPCRANRTGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPLPGPEDKEEPDGADLLSELRAENQRLTASLQELQEGLQQEVSRPGASGSERILLDILEHDWREAQDSRQELCQKLHTVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRAQGGSCLKACTSSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEAHTSAPGLICELRAEMGGLEVTGLILGLQEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDLLNRSLAIRVSGWSPSGGLELQDKSPDSLPVIGDRWSGAMVRRVLSGPGSARTEQKEPRAEGTGLEGSGLEAEAQQRTLPWNQGSTLPFLLDSKACQSFHEALDAWAKGSGTEPFYIRANLSLPERADPHALCVKAQEILRLVDAAHKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLLSSRHRSPRSNLKKRALGLVRPKPAGGAAGDSAEQLPAELCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAAESFSGEEQCTSSAPGAPKAWPSTPGLGNRIRAIQESVGKKKHCLLELGARGVKELVQSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGCGSSSEA", "length": 1096, "header": "tr|A0A9J7JHA6-1|A0A9J7JHA6_CRIGR Isoform 1 of Caspase recruitment domain-containing protein 10 OS=Cricetulus griseus OX=10029 GN=Card10 PE=4 SV=1 CANONICAL=A0A9J7JHA6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N523-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6/entry#A0A8C2N523-1", "sequence": { "sequence": "MWGGSGGRGAGGGANDPEGTAPSRRRSRRPSTEPAAQGSCGARDSEDAAMQGRADAGEADEEAGAGSGSEAEEDALWERIEGVRHRLTRALNPAKLTPYLRQCRVLDEQDEEEVLSTYRFPCRANRTGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPLPGPEDKEEPDGADLLSELRAENQRLTASLQELQEGLQQEVSRPGASGSERILLDILEHDWREAQDSRQELCQKLHTVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRAQGGSCLKACTSSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEAHTSEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDLLNRSLAIRVSGWSPSGGLELQDKSPDSLPVIGDRWSGAMVRRVLSGPGSARTEQKEPRAEGTGLEGSGLEAEAQQRTLPWNQGSTLPFLLDSKACQSFHEALDAWAKGSGTEPFYIRANLSLPERADPHALCVKAQEILRLVDAAHKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLLSSRHRSPRSNLKKRALGLVRPKPAGGAAGDSAEQLPAELCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAESFSGEEQCTSSAPGAPKAWPSTPGLGNRIRAIQESVGKKHCLLELGARGVKELVQSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGCGSSSEA", "length": 1069, "header": "tr|A0A8C2N523-1|A0A8C2N523_CRIGR Computationally mapped isoform of Caspase recruitment domain-containing protein 10 OS=Cricetulus griseus OX=10029 GN=Card10 PE=4 SV=1 CANONICAL=A0A9J7JHA6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FH14-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6/entry#A0A9J7FH14-1", "sequence": { "sequence": "MQGRADAGEADEEAGAGSGSEAEEDALWERIEGVRHRLTRALNPAKLTPYLRQCRVLDEQDEEEVLSTYRFPCRANRTGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPLPGPEDKEEPDGADLLSELRAENQRLTASLQELQEGLQQEVSRPGASGSERILLDILEHDWREAQDSRQELCQKLHTVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRAQGGSCLKACTSSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEAHTSAPGLICELRAEMGGLEVTGLILGLQEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDLLNRSLAIRVSGWSPSGGLELQDKSPDSLPVIGDRWSGAMVRRVLSGPGSARTEQKEPRAEGTGLEGSGLEAEAQQRTLPWNQGSTLPFLLDSKACQSFHEALDAWAKGSGTEPFYIRANLSLPERADPHALCVKAQEILRLVDAAHKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLLSSRHRSPRSNLKKRALGLVRPKPAGGAAGDSAEQLPAELCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAAESFSGEEQCTSSAPGAPKAWPSTPGLGNRIRAIQESVGKKKHCLLELGARGVKELVQSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGCGSSSEA", "length": 1047, "header": "tr|A0A9J7FH14-1|A0A9J7JHA6_CRIGR Computationally mapped isoform of Caspase recruitment domain-containing protein 10 OS=Cricetulus griseus OX=10029 GN=Card10 PE=4 SV=1 CANONICAL=A0A9J7JHA6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GPP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6/entry#A0A9J7GPP4-1", "sequence": { "sequence": "MQGRADAGEADEEAGAGSGSEAEEDALWERIEGVRHRLTRALNPAKLTPYLRQCRVLDEQDEEEVLSTYRFPCRANRTGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPLPGPEDKEEPDGADLLSELRAENQRLTASLQELQEGLQQEVSRPGASGSERILLDILEHDWREAQDSRQELCQKLHTVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRAQGGSCLKACTSSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEAHTSAPGLICELRAEMGGLEVTGLILGLQEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDLLNRSLAIRVSGWSPSGGLELQDKSPDSLPVIGDRWSGAMVRRVLSGPGSARTEQKEPRAEGTGLEGSGLEAEAQQRTLPWNQGSTLPFLLDSKACQSFHEALDAWAKGSGTEPFYIRANLSLPERADPHALCVKAQEILRLVDAAHKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLLSSRHRSPRSNLKKRALGLVRPKPAGGAAGDSAEQLPAELCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAESFSGEEQCTSSAPGAPKAWPSTPGLGNRIRAIQESVGKKHCLLELGARGVKELVQSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGCGSSSEA", "length": 1045, "header": "tr|A0A9J7GPP4-1|A0A9J7GPP4_CRIGR Computationally mapped isoform of Caspase recruitment domain-containing protein 10 OS=Cricetulus griseus OX=10029 GN=Card10 PE=4 SV=1 CANONICAL=A0A9J7JHA6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQ86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6/entry#A0A9J7GQ86-1", "sequence": { "sequence": "MQGRADAGEADEEAGAGSGSEAEEDALWERIEGVRHRLTRALNPAKLTPYLRQCRVLDEQDEEEVLSTYRFPCRANRTGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPLPGPEDKEEPDGADLLSELRAENQRLTASLQELQEGLQQEVSRPGASGSERILLDILEHDWREAQDSRQELCQKLHTVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRAQGGSCLKACTSSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEAHTSAPGLICELRAEMGGLEVTGLILGLQEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDLLNRSLAIRVSGWSPSGGLELQDKSPDSLPVIGDRWSGAMVRRVLSGPGSARTEQKEPRAEGTGLEGSGLEAEAQQRTLPWNQGSTLPFLLDSKACQSFHEALDAWAKGSGTEPFYIRANLSLPERADPHALCVKAQEILRLVDAAHKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLLSSRHRSPRSNLKKRALGLVRPKPAGGAAGDSAEQLPAELCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAESFSGEEQCTSSAPGAPKAWPSTPGLGNRIRAIQESVGKKKHCLLELGARGVKELVQSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGCGSSSEA", "length": 1046, "header": "tr|A0A9J7GQ86-1|A0A9J7GQ86_CRIGR Computationally mapped isoform of Caspase recruitment domain-containing protein 10 OS=Cricetulus griseus OX=10029 GN=Card10 PE=4 SV=1 CANONICAL=A0A9J7JHA6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GR76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6/entry#A0A9J7GR76-1", "sequence": { "sequence": "MQGRADAGEADEEAGAGSGSEAEEDALWERIEGVRHRLTRALNPAKLTPYLRQCRVLDEQDEEEVLSTYRFPCRANRTGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPLPGPEDKEEPDGADLLSELRAENQRLTASLQELQEGLQQEVSRPGASGSERILLDILEHDWREAQDSRQELCQKLHTVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRAQGGSCLKACTSSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEAHTSAPGLICELRAEMGGLEVTGLILGLQEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDLLNRSLAIRVSGWSPSGGLELQDKSPDSLPVIGDRWSGAMVRRVLSGPGSARTEQKEPRAEGTGLEGSGLEAEAQQRTLPWNQGSTLPFLLDSKACQSFHEALDAWAKGSGTEPFYIRANLSLPERADPHALCVKAQEILRLVDAAHKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLLSSRHRSPRSNLKKRALGLVRPKPAGGAAGDSAEQLPAELCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAAESFSGEEQCTSSAPGAPKAWPSTPGLGNRIRAIQESVGKKHCLLELGARGVKELVQSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGCGSSSEA", "length": 1046, "header": "tr|A0A9J7GR76-1|A0A9J7GR76_CRIGR Computationally mapped isoform of Caspase recruitment domain-containing protein 10 OS=Cricetulus griseus OX=10029 GN=Card10 PE=4 SV=1 CANONICAL=A0A9J7JHA6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GTC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6/entry#A0A9J7GTC2-1", "sequence": { "sequence": "MWGGSGGRGAGGGANDPEGTAPSRRRSRRPSTEPAAQGSCGARGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPLPGPEDKEEPDGADLLSELRAENQRLTASLQELQEGLQQEVSRPGASGSERILLDILEHDWREAQDSRQELCQKLHTVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRAQGGSCLKACTSSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEAHTSAPGLICELRAEMGGLEVTGLILGLQEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDLLNRSLAIRVSGWSPSGGLELQDKSPDSLPVIGDRWSGAMVRRVLSGPGSARTEQKEPRAEGTGLEGSGLEAEAQQRTLPWNQGSTLPFLLDSKACQSFHEALDAWAKGSGTEPFYIRANLSLPERADPHALCVKAQEILRLVDAAHKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLLSSRHRSPRSNLKKRALGLVRPKPAGGAAGDSAEQLPAELCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAAESFSGEEQCTSSAPGAPKAWPSTPGLGNRIRAIQESVGKKKHCLLELGARGVKELVQSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGCGSSSEA", "length": 1012, "header": "tr|A0A9J7GTC2-1|A0A9J7GTC2_CRIGR Computationally mapped isoform of Caspase recruitment domain-containing protein 10 isoform X10 OS=Cricetulus griseus OX=10029 GN=Card10 PE=4 SV=1 CANONICAL=A0A9J7JHA6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6/entry#A0A9J7GUX2-1", "sequence": { "sequence": "MQGRADAGEADEEAGAGSGSEAEEDALWERIEGVRHRLTRALNPAKLTPYLRQCRVLDEQDEEEVLSTYRFPCRANRTGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPLPGPEDKEEPDGADLLSELRAENQRLTASLQELQEGLQQEVSRPGASGSERILLDILEHDWREAQDSRQELCQKLHTVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRAQGGSCLKACTSSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEAHTSEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDLLNRSLAIRVSGWSPSGGLELQDKSPDSLPVIGDRWSGAMVRRVLSGPGSARTEQKEPRAEGTGLEGSGLEAEAQQRTLPWNQGSTLPFLLDSKACQSFHEALDAWAKGSGTEPFYIRANLSLPERADPHALCVKAQEILRLVDAAHKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLLSSRHRSPRSNLKKRALGLVRPKPAGGAAGDSAEQLPAELCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAAESFSGEEQCTSSAPGAPKAWPSTPGLGNRIRAIQESVGKKKHCLLELGARGVKELVQSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGCGSSSEA", "length": 1022, "header": "tr|A0A9J7GUX2-1|A0A9J7GUX2_CRIGR Computationally mapped isoform of Caspase recruitment domain-containing protein 10 OS=Cricetulus griseus OX=10029 GN=Card10 PE=4 SV=1 CANONICAL=A0A9J7JHA6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6/entry#A0A9J7JHA6-1", "sequence": { "sequence": "MWGGSGGRGAGGGANDPEGTAPSRRRSRRPSTEPAAQGSCGARDSEDAAMQGRADAGEADEEAGAGSGSEAEEDALWERIEGVRHRLTRALNPAKLTPYLRQCRVLDEQDEEEVLSTYRFPCRANRTGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPLPGPEDKEEPDGADLLSELRAENQRLTASLQELQEGLQQEVSRPGASGSERILLDILEHDWREAQDSRQELCQKLHTVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRAQGGSCLKACTSSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEAHTSAPGLICELRAEMGGLEVTGLILGLQEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDLLNRSLAIRVSGWSPSGGLELQDKSPDSLPVIGDRWSGAMVRRVLSGPGSARTEQKEPRAEGTGLEGSGLEAEAQQRTLPWNQGSTLPFLLDSKACQSFHEALDAWAKGSGTEPFYIRANLSLPERADPHALCVKAQEILRLVDAAHKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLLSSRHRSPRSNLKKRALGLVRPKPAGGAAGDSAEQLPAELCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAAESFSGEEQCTSSAPGAPKAWPSTPGLGNRIRAIQESVGKKKHCLLELGARGVKELVQSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGCGSSSEA", "length": 1096, "header": "tr|A0A9J7JHA6-1|A0A9J7JHA6_CRIGR Isoform 1 of Caspase recruitment domain-containing protein 10 OS=Cricetulus griseus OX=10029 GN=Card10 PE=4 SV=1 CANONICAL=A0A9J7JHA6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6/entry#A0A9J7K5M6-1", "sequence": { "sequence": "MQGRADAGEADEEAGAGSGSEAEEDALWERIEGVRHRLTRALNPAKLTPYLRQCRVLDEQDEEEVLSTYRFPCRANRTGRLIDILRCRGKRGFEAFLEALEFYYPEHFTLLTGQEPAQRCSMILDEEGPEGLTQFLMTEVRRLREARKSQLQREQQLQARGRALEEERAGLEQRLREQQQAQERCQRLREDWEAGSLELLRLKDENYMIAMRLAQLSEEKNSAVLRSRDLQLAVDQLKLKVSRLEEECALLRRARGPLPGPEDKEEPDGADLLSELRAENQRLTASLQELQEGLQQEVSRPGASGSERILLDILEHDWREAQDSRQELCQKLHTVQGELQWAEELRDKYLQEMEDLRLKHRTLLKDCDLYKHRMATVLAQLEEIEKERDQAIQSRDRIQLQYSQSLIEKDQYRKQVRGLEAERDELLTTVTSLEGTKAMLEAQLQRAQGGSCLKACTSSHSLCSNLSSTWSLSEFPSPLGGPEATGEAGGSEAHTSEEATDSEKEINRLSILPFPPSAGSILRRQREEDPEPPKRSFSSMSDITGSVTLKPWSPGLSSSSSSDSVWPLGKPEGLLARGCGLDLLNRSLAIRVSGWSPSGGLELQDKSPDSLPVIGDRWSGAMVRRVLSGPGSARTEQKEPRAEGTGLEGSGLEAEAQQRTLPWNQGSTLPFLLDSKACQSFHEALDAWAKGSGTEPFYIRANLSLPERADPHALCVKAQEILRLVDAAHKRRQEWFCTRVDPLTLRDLDRGTVPNYQRAQQLLEVQEKCLLSSRHRSPRSNLKKRALGLVRPKPAGGAAGDSAEQLPAELCSELERSLKPYSLVRPLLVSALRPVVLLPECLAPRLIRNLLDLPSSRLDFQVCPAESFSGEEQCTSSAPGAPKAWPSTPGLGNRIRAIQESVGKKHCLLELGARGVKELVQSEVYPIVIHVEVTEKNVREIRGLLGRPGWRDSELLRQCRGSEQWLWGLPCSWVQVPAHAWGHAEELAKVVRGRILQEQARLVWVERGSSRGGCGSSSEA", "length": 1020, "header": "tr|A0A9J7K5M6-1|A0A9J7K5M6_CRIGR Computationally mapped isoform of Caspase recruitment domain-containing protein 10 OS=Cricetulus griseus OX=10029 GN=Card10 PE=4 SV=1 CANONICAL=A0A9J7JHA6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 963, "start_aa": "Thr", "end_pos": 963, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr963", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FH14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH14" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FH14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH14" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762588", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762588", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6" } ], "pmid": "" }, { "name": "negative regulation of cell migration involved in sprouting angiogenesis", "id": "GO:0090051", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090051", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6" } ], "pmid": "" }, { "name": "positive regulation of protein localization to nucleus", "id": "GO:1900182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900182", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "CARD domain binding", "id": "GO:0050700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050700", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA6", "url": 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computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260294", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260294" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHN1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Setd1a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHN1", "locus": {} } ], "crossref": [ { "id": "cd12548", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12548", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19169", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19169", "database": "CDD", 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"MDQEGGGDGQKAPSFQWRNYKLIVDPALDPALRRPSQKVYRYDGVHFSVSDSKYTPVEDLQDPRCHVRSKNRDFSLPVPKFKLDEFYIGQIPLKEVTFARLNDNVRETFLKDMCRKYGEVEEVEILLHPRTRKHLGLARVLFTSTRGAKETVKNLHLTSVMGNIIHAQLDIKGQQRMKYYELIVNGSYTPQTVPTGGKALSEKFQSSGAATETTEARRRSSSDTAAYPAGTAVGGTPGNGTPCSQDTNFSSSRQDTPSSFGQFTPQSSQGTPYTPRGSTPYSQDSAYSSSSTSTSFKPRRSENSYQDSFSRRHFSASSAPATTSTATSATAAATAASSSTPSSSSSSSSSSSSSSSASQFRGSDSSYPAYYESWNRYQRHSSYPPRRATREDPPGAPFAENTSERFPPSYTSYLAPEPNRSTDQDYRPPASEAPPPDPPEPGGGGGGASNSGGGGGGGGAPSPEREEARTSPRPPSPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENNSAGPGARDAGGEVPSGAGHGPCTPPPAPANFEDVAPTGSGEPGAARESPKANGQNQASPCSSGEDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPPPYLSSLPLGYPPHQPAYLLPPHPDGPPPPEYPPPPPPPPPHIYDFVNSLELMDRLGAQWGGMPMSFQMQTQMLTRLHQLRQGKGLTAASAGPPGGAFGEAFLPFPPPQEATYGLPYALYTQGQESRGAYSREAYHLPLPMASEPLPSSSVSGEEARLPHREEAEMAESKALPSAGTVGRVLATLVQEMKSIMQRDLNRKMVENVAFGAFDQWWESKEEKAKPFQNAAKQQAKEEDKEKMKLKEPGMLSLVDWAKSGGITGIEAFAFGSGLRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEREKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEDDDEEDEEDEEREEAVDATKKEAEASDGEDEDSDSSSQCSLYADSDGENGSTSDSESSSSSSSSSSSTSSSSSSSSSSSSESSSEEEEQSAVIPPVSPTPREIPELLPAPDEKPETDRVVDAAVMPLPEKGMSPTRPAGSTEETPPNIPQPPPEPPAGPPDPAPRLDERPSSPIPLLPPPKKRRKTVSFSATEEAPAPEPPPAAPLQAKSPGPVSRKVPRVVERTIRNLPLDHASLVKSWPEEVSRGGRNRAGGRVRSAEEEEGTESGTEVDLAVLADLALTPARRGLATLPTGDDSEATETSDEAERPSPLLSHILLEHNYALAIKPPPATPAPRPLEPAPALAALFSSPADEVLEAPEVVVAEAEEPKQQLQQQQQHPEQKREEEEEEEEEEEGSSESSSSSSSSDEEGAIRRRSLRSHTRRRRPPLPPPPPPPPSFEPRSEFEQMTILYDIWNSGLDLEDMSYLRLTYERLLQQTSGADWLNDTHWVHHTITNLSTPKRKRRPQDGPREHQTGSARSEGYYPISKKEKDKYLDVCPVSARQLEGVDTQGTNRVLSERRSEQRRLLSAIGTSAIMDSDLLKLNQLKFRKKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKFPLEDNKIPCLCGTESCRGSLN", 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"subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 340, "start_aa": "Thr", "end_pos": 340, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr340", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 611, "start_aa": "Thr", "end_pos": 611, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr611", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 930, "start_aa": "Thr", "end_pos": 930, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr930", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FH67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH67" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FH67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH67" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753962", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753962", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHN1" } ], "pmid": "" }, { "name": "histone H3K4 monomethyltransferase activity", "id": "GO:0140945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140945", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHN1" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHN1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHN1" } ], "pmid": "" }, { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": 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"evidence": [ { "id": "60268", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60268" } ] }, { "id": "60272", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7JHN1-1", "A0A9J7JPP4-1" ], "evidence": [ { "id": "60272", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60272" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061IIR9", "gene_name": "Setd7", "activity": [ { "ec_number": "2.1.1.-", "activity": "", "evidence": [ { "id": "A0A061IIR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIR9" } ] } ] }, { "uniprot_ac": "A0A9J7FTH9", "gene_name": "Kmt2a", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = 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"uniprot_ac": "A0A9J7JWM7", "gene_name": "Kmt2c", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A9J7JWM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWM7" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0A9J7JWM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWM7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JHN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHN1" }, { "id": "PS50868", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50868" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Post-SET", "eco_id": "ECO_0000259", "start_pos": 1707, "end_pos": 1723, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JHN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHN1" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 172, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JHN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHN1" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 1584, "end_pos": 1701, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.364", "ec_name": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "2.1.1.364", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.364" }, { "id": "2.1.1.364", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.364" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 236, 340, 611, 930, 1091, 1324 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1041, "end_pos": 1043 }, { "start_pos": 1477, "end_pos": 1479 }, { "start_pos": 1488, "end_pos": 1490 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 528, "end_pos": 530 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 6 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 6 }, { "field": "exact_o_linked_sites", "count": 6 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 6 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 6 }, { "field": "exact_o_linked_sites", "count": 6 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JHD3-1", "uniprot_ac": "A0A9J7JHD3", "uniprot_id": "A0A9J7JHD3_CRIGR", "mass": { "chemical_mass": 64659.0, "monoisotopic_mass": 64659.0 }, "refseq": { "ac": "XP_007649131", "name": "xaa-Pro aminopeptidase 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649131" }, "gene_names": [ { "name": "Xpnpep3", "type": "recommended", "evidence": [ { "id": "A0A9J7JHD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3" } ] }, { "name": "Xpnpep3", "type": "synonym", "evidence": [ { "id": "XP_007649131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649131" } ] } ], "protein_names": [ { "name": "Xaa-Pro aminopeptidase 3", "type": "recommended", "evidence": [ { "id": "A0A9J7JHD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3/entry#names_and_taxonomy" } ] }, { "name": "3.4.11.9", "type": "synonym", "evidence": [ { "id": "A0A9J7JHD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3/entry#names_and_taxonomy" } ] }, { "name": "Aminopeptidase P3", "type": "synonym", "evidence": [ { "id": "A0A9J7JHD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3/entry#names_and_taxonomy" } ] }, { "name": "xaa-Pro aminopeptidase 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007649131", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649131" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614859.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007649131", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649131" } ] }, { "annotation": "Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala. Also shows low activity towards peptides with Ala or Ser at the P1 position. Promotes TNFRSF1B-mediated phosphorylation of MAPK8/JNK1 and MAPK9/JNK2, suggesting a function as an adapter protein for TNFRSF1B; the effect is independent of XPNPEP3 peptidase activity. May inhibit apoptotic cell death induced via TNF-TNFRSF1B signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FH73", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH73#function" }, { "database": "UniProtKB", "id": "ARBA00057617", "url": "https://www.uniprot.org/uniprotkb/ARBA00057617#function" }, { "database": "UniProtKB", "id": "A0A9J7JHD3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3#function" }, { "database": "UniProtKB", "id": "A0A9J7GR96", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR96#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHD3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Xpnpep3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763709", "url": "https://www.ncbi.nlm.nih.gov/gene/100763709", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763709", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763709", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FH73", "url": "https://www.orthodb.org/?gene=A0A9J7FH73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GR96", "url": "https://www.orthodb.org/?gene=A0A9J7GR96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JH07", "url": "https://www.orthodb.org/?gene=A0A9J7JH07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JHD3", "url": "https://www.orthodb.org/?gene=A0A9J7JHD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43226:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43226:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00557", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00557", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05195", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05195", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007649131", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649131", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FH73", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FH73-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GR96", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GR96-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH07", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH07-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHD3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K405", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K405", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K405-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K405-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSGGWVGSLCGGRAKTQPGDVTALRRYGKKARERRLPEGAGRLAGFLATRPCWRLLCLQFVIFLPDACVLTMPSLLSTPKLVPVIARLRCLSGCMSCLYQRYSSLQPVQKKIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMDLIHKEAQGHSGTDHTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSCSGKQLPSHKAMLFVPQRDPGRELWDGPRSGSDGAIALTGVDEAYTLEEFQHLIPKLKAETSMVWYDWMKPSHAQLHSDYMQHLTEAKARSKNKVRSVQQLIQRLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRACLRLCSPGTSLENIYSMMMTLMGQTLKDLGIMKSSKENAFKAARKYCPHHVSHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEMNDIEQICSRGS", "length": 578, "header": "tr|A0A9J7JHD3-1|A0A9J7JHD3_CRIGR Isoform 1 of Xaa-Pro aminopeptidase 3 OS=Cricetulus griseus OX=10029 GN=Xpnpep3 PE=3 SV=1 CANONICAL=A0A9J7JHD3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FH73-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3/entry#A0A9J7FH73-1", "sequence": { "sequence": "MNSRANIARRTPTLRVQYGCMSCLYQRYSSLQPVQKKIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMDLIHKEAQGHSGTDHTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSCSGKQLPSHKAMLFVPQRDPGRELWDGPRSGSDGAIALTGVDEAYTLEEFQHLIPKLKAETSMVWYDWMKPSHAQLHSDYMQHLTEAKARSKNKVRSVQQLIQRLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRACLRLCSPGTSLENIYSMMMTLMGQTLKDLGIMKSSKENAFKAARKYCPHHVSHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEMNDIEQICSRGS", "length": 503, "header": "tr|A0A9J7FH73-1|A0A9J7JHD3_CRIGR Computationally mapped isoform of Xaa-Pro aminopeptidase 3 OS=Cricetulus griseus OX=10029 GN=Xpnpep3 PE=3 SV=1 CANONICAL=A0A9J7JHD3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GR96-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3/entry#A0A9J7GR96-1", "sequence": { "sequence": "MRVHLEDLLKHSKSGGCMSCLYQRYSSLQPVQKKIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMDLIHKEAQGHSGTDHTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSCSGKQLPSHKAMLFVPQRDPGRELWDGPRSGSDGAIALTGVDEAYTLEEFQHLIPKLKAETSMVWYDWMKPSHAQLHSDYMQHLTEAKARSKNKVRSVQQLIQRLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRACLRLCSPGTSLENIYSMMMTLMGQTLKDLGIMKSSKENAFKAARKYCPHHVSHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEMNDIEQICSRGS", "length": 500, "header": "tr|A0A9J7GR96-1|A0A9J7GR96_CRIGR Computationally mapped isoform of Xaa-Pro aminopeptidase 3 OS=Cricetulus griseus OX=10029 GN=Xpnpep3 PE=3 SV=1 CANONICAL=A0A9J7JHD3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JH07-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3/entry#A0A9J7JH07-1", "sequence": { "sequence": "MPSGGWVGSLCGGRAKTQPGDVTALRRYGKKARERRLPEGAGRLAGFLATRPCWRLLCLQFVIFLPDACVLTMPSLLSTPKLVPVIARLRCLSGCMSCLYQRYSSLQPVQKKIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMDLIHKEAQGHSGTDHTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSCSGKQLPSHKAMLFVPQRDPGRELWDGPRSGSDGAIALTGVDEAYTLEEFQHLIPKLKAETSMVWYDWMKPSHAQLHSDYMQHLTEAKARSKNKVRSVQQLIQRLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRACLRLCSPGTSLENIYSMMMTLMGQTLKDLGIMKSSKENAFKAARKYCPHHVSHYLGMDVHDTPDMPRSLPLQPGMVITIEPDHMVCLI", "length": 530, "header": "tr|A0A9J7JH07-1|A0A9J7JH07_CRIGR Computationally mapped isoform of Xaa-Pro aminopeptidase OS=Cricetulus griseus OX=10029 GN=Xpnpep3 PE=3 SV=1 CANONICAL=A0A9J7JHD3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3/entry#A0A9J7JHD3-1", "sequence": { "sequence": "MPSGGWVGSLCGGRAKTQPGDVTALRRYGKKARERRLPEGAGRLAGFLATRPCWRLLCLQFVIFLPDACVLTMPSLLSTPKLVPVIARLRCLSGCMSCLYQRYSSLQPVQKKIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMDLIHKEAQGHSGTDHTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSCSGKQLPSHKAMLFVPQRDPGRELWDGPRSGSDGAIALTGVDEAYTLEEFQHLIPKLKAETSMVWYDWMKPSHAQLHSDYMQHLTEAKARSKNKVRSVQQLIQRLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRACLRLCSPGTSLENIYSMMMTLMGQTLKDLGIMKSSKENAFKAARKYCPHHVSHYLGMDVHDTPDMPRSLPLQPGMVITIEPGIYIPEDDKDAPEKFRGLGVRIEDDVVVTQDSPLILSADCPKEMNDIEQICSRGS", "length": 578, "header": "tr|A0A9J7JHD3-1|A0A9J7JHD3_CRIGR Isoform 1 of Xaa-Pro aminopeptidase 3 OS=Cricetulus griseus OX=10029 GN=Xpnpep3 PE=3 SV=1 CANONICAL=A0A9J7JHD3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K405-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3/entry#A0A9J7K405-1", "sequence": { "sequence": "MPSGGWVGSLCGGRAKTQPGDVTALRRYGKKARERRLPEGAGRLAGFLATRPCWRLLCLQFVIFLPDACVLTMPSLLSTPKLVPVIARLRCLSGCMSCLYQRYSSLQPVQKKIPNRYLGQPSPVTHPHLLRPGEVTPGLSQVEYALRRHKLMDLIHKEAQGHSGTDHTVVVLSNPTYYMSNDIPYTFHQDNNFLYLCGFQEPDSILVLQSCSGKQLPSHKAMLFVPQRDPGRELWDGPRSGSDGAIALTGVDEAYTLEEFQHLIPKLKAETSMVWYDWMKPSHAQLHSDYMQHLTEAKARSKNKVRSVQQLIQRLRLIKSPAEIKRMQIAGKLTSEAFIETMFASKAPVDEAFLYAKFEFECRARGADILAYPPVVAGGNRSNTLHYVKNNQLIKDGEMVLLDGGCESSCYVSDITRTWPVNGRFTAPQAELYEAVLEIQRACLRLCSPGTSLENIYSMMMTLMGQTLKDLGIMKSSKENAFKAARKYCPHHVSHYLGMDVHDTPDMPRSLPLQPGMVITIEPVAS", "length": 526, "header": "tr|A0A9J7K405-1|A0A9J7K405_CRIGR Computationally mapped isoform of Xaa-Pro aminopeptidase OS=Cricetulus griseus OX=10029 GN=Xpnpep3 PE=3 SV=1 CANONICAL=A0A9J7JHD3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FH73", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH73" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FH73", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH73" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763709", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763709", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHD3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHD3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "manganese ion binding", "id": "GO:0030145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030145", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHD3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3" } ], "pmid": "" }, { "name": "metalloaminopeptidase activity", "id": "GO:0070006", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070006", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHD3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 380, "end_pos": 382, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JHD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD3" }, { "id": "SM01011", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Aminopeptidase P N-terminal", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 285, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.11.9", "ec_name": "Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.", "evidence": [ { "id": "3.4.11.9", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.11.9" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 136 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 380, "end_pos": 382 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JHA0-1", "uniprot_ac": "A0A9J7JHA0", "uniprot_id": "A0A9J7JHA0_CRIGR", "mass": { "chemical_mass": 56121.0, "monoisotopic_mass": 56121.0 }, "refseq": { "ac": "XP_027260278", "name": "transforming growth factor beta-1-induced transcript 1 protein isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260278" }, "gene_names": [ { "name": "Tgfb1i1", "type": "recommended", "evidence": [ { "id": "A0A9J7JHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ] }, { "name": "Tgfb1i1", "type": "synonym", "evidence": [ { "id": "XP_027260278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260278" } ] } ], "protein_names": [ { "name": "Transforming growth factor beta-1-induced transcript 1 protein", "type": "recommended", "evidence": [ { "id": "A0A9J7JHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0/entry#names_and_taxonomy" } ] }, { "name": "transforming growth factor beta-1-induced transcript 1 protein isoform X4", "type": "synonym", "evidence": [ { "id": "XP_027260278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260278" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260278" } ] }, { "annotation": "Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0#function" }, { "database": "UniProtKB", "id": "PIRNR037881", "url": "https://www.uniprot.org/uniprotkb/PIRNR037881#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tgfb1i1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHA0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09336", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09336", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09337", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09409", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09409", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09412", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09412", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771750", "url": "https://www.ncbi.nlm.nih.gov/gene/100771750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771750", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771750", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JHA0", "url": "https://www.orthodb.org/?gene=A0A9J7JHA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24214:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24214:SF62", 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPCSPFIAPPSTVSQRVPASIHGHGPASNSLTSPPRPRPHRTRPPPCSPQAVCQRTAMEDLDALLSDLETTTSHMSRLGAPKERPPETLTPPPPYGHQPQTGSGEPSGASGDKDHLYSTVCKPRSPKPVAPVAPPFSSSSGVLGNGLCELDRLLQELNATQFNITDEIMSQFPSSKMAEGEEKEDQTEDKNTPTVPPSTFPVPSKPSATSATLELDRLMASLSDFRVQNHLPASGPSQPPAASSTQEGCPSPPGQTSKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGKAWHPEHFLCSGCSTTLGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGEEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECLAPFSGGSFFEHEGRPLCENHFHAQRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG", "length": 519, "header": "tr|A0A9J7JHA0-1|A0A9J7JHA0_CRIGR Isoform 1 of Transforming growth factor beta-1-induced transcript 1 protein OS=Cricetulus griseus OX=10029 GN=Tgfb1i1 PE=3 SV=1 CANONICAL=A0A9J7JHA0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FHR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0/entry#A0A9J7FHR9-1", "sequence": { "sequence": "MSRLGAPKERPPETLTPPPPYGHQPQTGSGEPSGASGDKDHLYSTVCKPRSPKPVAPVAPPFSSSSGVLGNGLCELDRLLQELNATQFNITDEIMSQFPSSKMAEGEEKEDQTEDKNTPTVPPSTFPVPSKPSATSATLELDRLMASLSDFRVQNHLPASGPSQPPAASSTQEGCPSPPGQTSKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGKAWHPEHFLCSGCSTTLGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGEEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECLAPFSGGSFFEHEGRPLCENHFHAQRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG", "length": 444, "header": "tr|A0A9J7FHR9-1|A0A9J7JHA0_CRIGR Computationally mapped isoform of Transforming growth factor beta-1-induced transcript 1 protein OS=Cricetulus griseus OX=10029 GN=Tgfb1i1 PE=3 SV=1 CANONICAL=A0A9J7JHA0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FKZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0/entry#A0A9J7FKZ9-1", "sequence": { "sequence": "MAISHRQGLENLQEPPGTRIICTVCKPRSPKPVAPVAPPFSSSSGVLGNGLCELDRLLQELNATQFNITDEIMSQFPSSKMAEGEEKEDQTEDKNTPTVPPSTFPVPSKPSATSATLELDRLMASLSDFRVQNHLPASGPSQPPAASSTQEGCPSPPGQTSKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGKAWHPEHFLCSGCSTTLGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGEEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECLAPFSGGSFFEHEGRPLCENHFHAQRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG", "length": 422, "header": "tr|A0A9J7FKZ9-1|A0A9J7JHA0_CRIGR Computationally mapped isoform of Transforming growth factor beta-1-induced transcript 1 protein OS=Cricetulus griseus OX=10029 GN=Tgfb1i1 PE=3 SV=1 CANONICAL=A0A9J7JHA0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0/entry#A0A9J7JHA0-1", "sequence": { "sequence": "MSPCSPFIAPPSTVSQRVPASIHGHGPASNSLTSPPRPRPHRTRPPPCSPQAVCQRTAMEDLDALLSDLETTTSHMSRLGAPKERPPETLTPPPPYGHQPQTGSGEPSGASGDKDHLYSTVCKPRSPKPVAPVAPPFSSSSGVLGNGLCELDRLLQELNATQFNITDEIMSQFPSSKMAEGEEKEDQTEDKNTPTVPPSTFPVPSKPSATSATLELDRLMASLSDFRVQNHLPASGPSQPPAASSTQEGCPSPPGQTSKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGKAWHPEHFLCSGCSTTLGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGEEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECLAPFSGGSFFEHEGRPLCENHFHAQRGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG", "length": 519, "header": "tr|A0A9J7JHA0-1|A0A9J7JHA0_CRIGR Isoform 1 of Transforming growth factor beta-1-induced transcript 1 protein OS=Cricetulus griseus OX=10029 GN=Tgfb1i1 PE=3 SV=1 CANONICAL=A0A9J7JHA0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FHR9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHR9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FHR9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHR9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771750", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771750", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "muscle alpha-actinin binding", "id": "GO:0051371", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051371", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "pmid": "" }, { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "pmid": "" }, { "name": "filamentous actin", "id": "GO:0031941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031941", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "pmid": "" }, { "name": "nuclear matrix", "id": "GO:0016363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016363", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "heart development", "id": "GO:0007507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007507", "evidence": [ { 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"database": "UniProtKB", "id": "A0A9J7JHA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JHA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHA0" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 284, "end_pos": 343, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 164, "end_pos": 166 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JHC0-1", "uniprot_ac": "A0A9J7JHC0", "uniprot_id": "A0A9J7JHC0_CRIGR", "mass": { "chemical_mass": 87899.0, "monoisotopic_mass": 87899.0 }, "refseq": { "ac": "XP_027258039", "name": "translocation protein SEC63 homolog isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258039" }, "gene_names": [ { "name": "Sec63", "type": "recommended", "evidence": [ { "id": "A0A9J7JHC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0" } ] }, { "name": "Sec63", "type": "synonym", "evidence": [ { "id": "XP_027258039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258039" } ] } ], "protein_names": [ { "name": "Translocation protein SEC63 homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7JHC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0/entry#names_and_taxonomy" } ] }, { "name": "DnaJ homolog subfamily C member 23", "type": "synonym", "evidence": [ { "id": "A0A9J7JHC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0/entry#names_and_taxonomy" } ] }, { "name": "translocation protein SEC63 homolog isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027258039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258039" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027258039", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258039" } ] }, { "annotation": "Mediates cotranslational and post-translational transport of certain precursor polypeptides across endoplasmic reticulum (ER). Proposed to play an auxiliary role in recognition of precursors with short and apolar signal peptides. May cooperate with SEC62 and HSPA5/BiP to facilitate targeting of small presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FI81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI81#function" }, { "database": "UniProtKB", "id": "ARBA00059604", "url": "https://www.uniprot.org/uniprotkb/ARBA00059604#function" }, { "database": "UniProtKB", "id": "A0A9J7JHC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sec63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHC0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100775020", "url": "https://www.ncbi.nlm.nih.gov/gene/100775020", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100775020", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775020", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JHC0", "url": "https://www.orthodb.org/?gene=A0A9J7JHC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24075:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24075:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02889", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02889", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027258039", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258039", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FI81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FI81-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQIRLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHSLLHFLEDDKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPVEDGQSDANKNKTKGGWQQKSKGPKKMPKSKKKKPLKKKPTAVPLPQAKQQKQKQANGVVGSETAVKEEEDDISDKGSDSEEEETNRDSQSEKDDGSDRESDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEGDD", "length": 760, "header": "tr|A0A9J7JHC0-1|A0A9J7JHC0_CRIGR Isoform 1 of Translocation protein SEC63 homolog OS=Cricetulus griseus OX=10029 GN=Sec63 PE=4 SV=1 CANONICAL=A0A9J7JHC0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FI81-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0/entry#A0A9J7FI81-1", "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQIRLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHSLLHFLEDDKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPVEDGSDANKNKTKGGWQQKSKGPKKMPKSKKKKPLKKKPTAVPLPQAKQQKQKQANGVVGSETAVKEEEDDISDKGSDSEEEETNRDSQSEKDDGSDRESDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEGDD", "length": 759, "header": "tr|A0A9J7FI81-1|A0A9J7JHC0_CRIGR Computationally mapped isoform of Translocation protein SEC63 homolog OS=Cricetulus griseus OX=10029 GN=Sec63 PE=4 SV=1 CANONICAL=A0A9J7JHC0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0/entry#A0A9J7JHC0-1", "sequence": { "sequence": "MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQIRLKNIRKVYGRCMWYRLRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALPAWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIIMARSREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDRHSLLHFLEDDKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPVEDGQSDANKNKTKGGWQQKSKGPKKMPKSKKKKPLKKKPTAVPLPQAKQQKQKQANGVVGSETAVKEEEDDISDKGSDSEEEETNRDSQSEKDDGSDRESDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEGDD", "length": 760, "header": "tr|A0A9J7JHC0-1|A0A9J7JHC0_CRIGR Isoform 1 of Translocation protein SEC63 homolog OS=Cricetulus griseus OX=10029 GN=Sec63 PE=4 SV=1 CANONICAL=A0A9J7JHC0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FI81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI81" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FI81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI81" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100775020", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775020", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "post-translational protein targeting to endoplasmic reticulum membrane", "id": "GO:0006620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006620", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0" } ], "pmid": "" }, { "name": "SRP-dependent cotranslational protein targeting to membrane", "id": "GO:0006614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006614", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0" } ], "pmid": "" }, { "name": "protein transmembrane transporter activity", "id": "GO:0008320", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Sec62/Sec63 complex", "id": "GO:0031207", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031207", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JHC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHC0" }, { "id": "PS50076", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50076" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "J", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 165, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 461, "end_pos": 463 }, { "start_pos": 507, "end_pos": 509 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JHH5-1", "uniprot_ac": "A0A9J7JHH5", "uniprot_id": "A0A9J7JHH5_CRIGR", "mass": { "chemical_mass": 41557.0, "monoisotopic_mass": 41557.0 }, "refseq": { "ac": "XP_016835119", "name": "selection and upkeep of intraepithelial T-cells protein 1-like isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835119" }, "gene_names": [ { "name": "LOC100758417", "type": "recommended", "evidence": [ { "id": "A0A9J7JHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5" } ] }, { "name": "LOC100758417", "type": "synonym", "evidence": [ { "id": "XP_016835119", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835119" } ] } ], "protein_names": [ { "name": "Selection and upkeep of intraepithelial T-cells protein 1-like isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7JHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5/entry#names_and_taxonomy" } ] }, { "name": "selection and upkeep of intraepithelial T-cells protein 1-like isoform X3", "type": "synonym", "evidence": [ { "id": "XP_016835119", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835119" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613624.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016835119", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835119" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100758417", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHH5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHH5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05713", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05713", "database": "CDD", "categories": [ "Protein 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"categories": [ "Protein Classification" ] }, { "id": "IPR053896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758417", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758417", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FII5", "url": "https://www.orthodb.org/?gene=A0A9J7FII5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JHH5", "url": "https://www.orthodb.org/?gene=A0A9J7JHH5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24100:SF129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24100:SF129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22705", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22705", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016835119", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835119", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FII5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FII5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FII5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FII5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4S4", "url": 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"sequence": "MVTGLEGPVVAPLGGNLELSCQLFPSQDAQHMEIRWFRHHYTQPVHLYRDGKDIYGETILKYVERTELLKDAIGEGRVTLRIFNVTVDDDGPYHCVFKDSNFYEEHITEVKVTAVGLQVQIHVHPPNTKGVIVECNSGGWFPKPLMEWRDSRGEVIPAATKSHSQDEGKLFNIKMILLIRDSSSPKVTCYLQNPLTGQEQRTSVAISDAFFSWNRKWKMILSVILFVMVFSVMDSSCQIYIRKQNRWCTWTAPWVIGILILVLSVLTVIGVLVWLHMKQRVPISDAHFELDTLWLEDISVILCALMVSATMLISYVYFKLKAHLQNYHLSEVSSSK", "length": 336, "header": "tr|A0A9J7FII5-1|A0A9J7JHH5_CRIGR Computationally mapped isoform of Selection and upkeep of intraepithelial T-cells protein 1-like isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100758417 PE=3 SV=1 CANONICAL=A0A9J7JHH5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5/entry#A0A9J7JHH5-1", "sequence": { "sequence": "MGSTGPCFYGHCIVMFLLHMITPSSEKFMVTGLEGPVVAPLGGNLELSCQLFPSQDAQHMEIRWFRHHYTQPVHLYRDGKDIYGETILKYVERTELLKDAIGEGRVTLRIFNVTVDDDGPYHCVFKDSNFYEEHITEVKVTAVGLQVQIHVHPPNTKGVIVECNSGGWFPKPLMEWRDSRGEVIPAATKSHSQDEGKLFNIKMILLIRDSSSPKVTCYLQNPLTGQEQRTSVAISDAFFSWNRKWKMILSVILFVMVFSVMDSSCQIYIRKQNRWCTWTAPWVIGILILVLSVLTVIGVLVWLHMKQRVPISDAHFELDTLWLEDISVILCALMVSATMLISYVYFKLKAHLQNYHLSEVSSSK", "length": 364, "header": "tr|A0A9J7JHH5-1|A0A9J7JHH5_CRIGR Isoform 1 of Selection and upkeep of intraepithelial T-cells protein 1-like isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100758417 PE=3 SV=1 CANONICAL=A0A9J7JHH5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K4S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5/entry#A0A9J7K4S4-1", "sequence": { "sequence": "MVTGLEGPVVAPLGGNLELSCQLFPSQDAQHMEIRWFRHHYTQPVHLYRDGKDIYGETILKYVERTELLKDAIGEGRVTLRIFNVTVDDDGPYHCVFKDSNFYEEHITEVKVTAVGLQVQIHVHPPNTKGVIVECNSGGWFPKPLMEWRDSRGEVIPAATKSHSQDEGKLFNIKMILLIRDSSSPKVTCYLQNPLTGQEQRTSVAISDAFFSWNRKWKMILSVILFVMVFSVMDSSCQIYIRKQNRWCTWTAPWVIGILILVLSVLTVIGVLVWLHMKQRVPISDAHFELDTLWLEDISVILCALMVSATMLISYVYFKLKGVLR", "length": 325, "header": "tr|A0A9J7K4S4-1|A0A9J7K4S4_CRIGR Computationally mapped isoform of Selection and upkeep of intraepithelial T-cells protein 1-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100758417 PE=3 SV=1 CANONICAL=A0A9J7JHH5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FII5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FII5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FII5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FII5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758417", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758417", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "T cell activation", "id": "GO:0042110", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042110", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5" } ], "pmid": "" }, { "name": "T cell receptor signaling pathway", "id": "GO:0050852", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050852", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5" } ], "pmid": "" }, { "name": "regulation of T cell activation", "id": "GO:0050863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050863", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5" } ], "pmid": "" }, { "name": "regulation of leukocyte cell-cell adhesion", "id": "GO:1903037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903037", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JHH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHH5" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 141, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JI99-1", "uniprot_ac": "A0A9J7JI99", "uniprot_id": "A0A9J7JI99_CRIGR", "mass": { "chemical_mass": 52637.0, "monoisotopic_mass": 52637.0 }, "refseq": { "ac": "XP_027261679", "name": "phosphatidylcholine-sterol acyltransferase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261679" }, "gene_names": [ { "name": "Lcat", "type": "recommended", "evidence": [ { "id": "A0A9J7JI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99" } ] }, { "name": "Lcat", "type": "synonym", "evidence": [ { "id": "XP_027261679", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261679" } ] } ], "protein_names": [ { "name": "Phosphatidylcholine-sterol acyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7JI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.43", "type": "synonym", "evidence": [ { "id": "A0A9J7JI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99/entry#names_and_taxonomy" } ] }, { "name": "Lecithin-cholesterol acyltransferase", "type": "synonym", "evidence": [ { "id": "A0A9J7JI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99/entry#names_and_taxonomy" } ] }, { "name": "Phospholipid-cholesterol acyltransferase", "type": "synonym", "evidence": [ { "id": "A0A9J7JI99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99/entry#names_and_taxonomy" } ] }, { "name": "phosphatidylcholine-sterol acyltransferase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027261679", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261679" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027261679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261679" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lcat", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99", "locus": {} } ], "crossref": [ { "id": "A0A9J7JI99", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JI99", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751451", "url": "https://www.ncbi.nlm.nih.gov/gene/100751451", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751451", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751451", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JI99", "url": "https://www.orthodb.org/?gene=A0A9J7JI99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11440", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11440", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02450", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02450", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027261679", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261679", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21204", "url": "https://www.rhea-db.org/rhea/21204", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FJT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVLWGQGSAAWFLHLPCLKGAWMLQYWWGSRKCGGEKIDMVRGCGKWRGGRFLVVGWGVGEKPRSPEQKLVPTVPGCLGNRLEAKLDKPDVVNWLCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGHVSNAPGVQIRVPGFGKTYSVEYLDDNKLAGYMHTLVQNLVNNGYVRDETVRAAPYDWRLEPSQQDEYYRKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLYFLLRQPQSWKDRFIDGFISLGAPWGGSIKPMLVMASGDNQGIPFMSSIKLREEQRITTTSPWMFPARQVWPEDHVFISTPNFNYTGQDFKRFFEDLHFEDGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPHTYIYDHSFPYKDPVAALYEDGDDTVATRSTELCGRWHGHQSQPVHLMPMNGTEHLNMVFSNKTLEHINAILSGAYRHGIPEAPAASPGPPPPE", "length": 463, "header": "tr|A0A9J7JI99-1|A0A9J7JI99_CRIGR Isoform 1 of Phosphatidylcholine-sterol acyltransferase OS=Cricetulus griseus OX=10029 GN=Lcat PE=3 SV=1 CANONICAL=A0A9J7JI99-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FJT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99/entry#A0A9J7FJT0-1", "sequence": { "sequence": "MGLPGSPWQWVLLLLGLLLPPATPFWLLNVLFPPQTTPKAELSNHTRPVILVPGCLGNRLEAKLDKPDVVNWLCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGHVSNAPGVQIRVPGFGKTYSVEYLDDNKLAGYMHTLVQNLVNNGYVRDETVRAAPYDWRLEPSQQDEYYRKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLYFLLRQPQSWKDRFIDGFISLGAPWGGSIKPMLVMASGDNQGIPFMSSIKLREEQRITTTSPWMFPARQVWPEDHVFISTPNFNYTGQDFKRFFEDLHFEDGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPHTYIYDHSFPYKDPVAALYEDGDDTVATRSTELCGRWHGHQSQPVHLMPMNGTEHLNMVFSNKTLEHINAILSGAYRHGIPEAPAASPGPPPPE", "length": 440, "header": "tr|A0A9J7FJT0-1|A0A9J7JI99_CRIGR Computationally mapped isoform of Phosphatidylcholine-sterol acyltransferase OS=Cricetulus griseus OX=10029 GN=Lcat PE=3 SV=1 CANONICAL=A0A9J7JI99-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JI99-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99/entry#A0A9J7JI99-1", "sequence": { "sequence": "MFVLWGQGSAAWFLHLPCLKGAWMLQYWWGSRKCGGEKIDMVRGCGKWRGGRFLVVGWGVGEKPRSPEQKLVPTVPGCLGNRLEAKLDKPDVVNWLCYRKTEDFFTIWLDLNMFLPLGVDCWIDNTRVVYNRSSGHVSNAPGVQIRVPGFGKTYSVEYLDDNKLAGYMHTLVQNLVNNGYVRDETVRAAPYDWRLEPSQQDEYYRKLAGLVEEMYAAYGKPVFLIGHSLGCLHVLYFLLRQPQSWKDRFIDGFISLGAPWGGSIKPMLVMASGDNQGIPFMSSIKLREEQRITTTSPWMFPARQVWPEDHVFISTPNFNYTGQDFKRFFEDLHFEDGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPHTYIYDHSFPYKDPVAALYEDGDDTVATRSTELCGRWHGHQSQPVHLMPMNGTEHLNMVFSNKTLEHINAILSGAYRHGIPEAPAASPGPPPPE", "length": 463, "header": "tr|A0A9J7JI99-1|A0A9J7JI99_CRIGR Isoform 1 of Phosphatidylcholine-sterol acyltransferase OS=Cricetulus griseus OX=10029 GN=Lcat PE=3 SV=1 CANONICAL=A0A9J7JI99-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FJT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJT0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FJT0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJT0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751451", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751451", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cholesterol metabolic process", "id": "GO:0008203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008203", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylcholine-sterol O-acyltransferase activity", "id": "GO:0004607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004607", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI99", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI99" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21204", "name": "", "equation": "a sterol + a 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"synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.1.43", "ec_name": "a sterol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a sterol ester + a 1-acyl-sn-glycero-3-phosphocholine.", "evidence": [ { "id": "2.3.1.43", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.3.1.43" }, { "id": "2.3.1.43", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.43" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 431, "end_pos": 433 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262273" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100770307", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57", "locus": {} } ], "crossref": [ { "id": "cd05516", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05516", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18063", "database": "CDD", 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF07529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07533", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07533", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262273", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262273", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FJY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FKL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FKL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FNH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FNH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FPL9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FPL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ57-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JK76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JK76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTPTDPAAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMSTMGSADFPQEAIHQMHKPMDGIHDKGIIDDAHCGSMKGASMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPISGGGPTPPQMPPSQPGPLIPGDLQAMNQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGMQQQQQQQQQQQQQQQPQQPQQQPQQPQQQAQPQPQQQQPALVSYNRPSGPGQEMLMSGQSTPQKLSAPAPSGRPSPAPPAAAQPTATAVPGPSVQQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQELESLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRRKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVEKDPVKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPCNSQLEIEGNRSGPALYPHVSKHSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEEESNEEEEEDDEEESESEGKTLHLAPSTYRAISTAKSVKVKIKLNKKEEKGRDTGKGKKRPNRGKAKPVVSDFDSDEEQDENEQSEASGTDDE", "length": 1621, "header": "tr|A0A9J7JJ57-1|A0A9J7JJ57_CRIGR Isoform 1 of Probable global transcription activator SNF2L2 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100770307 PE=3 SV=1 CANONICAL=A0A9J7JJ57-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FJY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57/entry#A0A9J7FJY9-1", "sequence": { "sequence": "MSTPTDPAAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMSTMGSADFPQEAIHQMHKPMDGIHDKGIIDDAHCGSMKGASMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPISGGGPTPPQMPPSQPGPLIPGDLQAMNQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGMQQQQQQQQQQQQQQQPQQPQQQPQQPQQQAQPQPQQQQPALVSYNRPSGPGQEMLMSGQSTPQKLSAPAPSGRPSPAPPAAAQPTATAVPGPSVQQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQELESLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRRKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVEKDPVKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEEESNEEEEEDDEEESESEGKTLHLAPSTYRAISTAKSVKVKIKLNKKEEKGRDTGKGKKRPNRGKAKPVVSDFDSDEEQDENEQSEASGTDDE", "length": 1590, "header": "tr|A0A9J7FJY9-1|A0A9J7JJ57_CRIGR Computationally mapped isoform of Probable global transcription activator SNF2L2 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100770307 PE=3 SV=1 CANONICAL=A0A9J7JJ57-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FKL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57/entry#A0A9J7FKL6-1", "sequence": { "sequence": "MSTPTDPAAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMSTMGSADFPQEAIHQMHKPMDGIHDKGIIDDAHCGSMKGASMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPISGGGPTPPQMPPSQPGPLIPGDLQAMNQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGMQQQQQQQQQQQQQQQPQQPQQQPQQPQQQAQPQPQQQQPALVSYNRPSGPGQEMLMSGQSTPQKLSAPAPSGRPSPAPPAAAQPTATAVPGPSVQQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQELESLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRRKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVEKDPVKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPCNSQLEIEGNRSGPALYPHVSKHSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEEESNEEEEEDDEEESESEAKSVKVKIKLNKKEEKGRDTGKGKKRPNRGKAKPVVSDFDSDEEQDENEQSEASGTDDE", "length": 1605, "header": "tr|A0A9J7FKL6-1|A0A9J7JJ57_CRIGR Computationally mapped isoform of Probable global transcription activator SNF2L2 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100770307 PE=3 SV=1 CANONICAL=A0A9J7JJ57-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FNH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57/entry#A0A9J7FNH7-1", "sequence": { "sequence": "MSTPTDPAAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMSTMGSADFPQEAIHQMHKPMDGIHDKGIIDDAHCGSMKGASMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPISGGGPTPPQMPPSQPGPLIPGDLQAMNQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGMQQQQQQQQQQQQQQQPQQPQQQPQQPQQQAQPQPQQQQPALVSYNRPSGPGQEMLMSGQSTPQKLSAPAPSGRPSPAPPAAAQPTATAVPGPSVQQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQELESLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRRKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVEKDPVKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPCNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEEESNEEEEEDDEEESESEAKSVKVKIKLNKKEEKGRDTGKGKKRPNRGKAKPVVSDFDSDEEQDENEQSEASGTDDE", "length": 1592, "header": "tr|A0A9J7FNH7-1|A0A9J7JJ57_CRIGR Computationally mapped isoform of Probable global transcription activator SNF2L2 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100770307 PE=3 SV=1 CANONICAL=A0A9J7JJ57-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FPL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57/entry#A0A9J7FPL9-1", "sequence": { "sequence": "MSTPTDPAAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMSTMGSADFPQEAIHQMHKPMDGIHDKGIIDDAHCGSMKGASMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPISGGGPTPPQMPPSQPGPLIPGDLQAMNQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGMQQQQQQQQQQQQQQQPQQPQQQPQQPQQQAQPQPQQQQPALVSYNRPSGPGQEMLMSGQSTPQKLSAPAPSGRPSPAPPAAAQPTATAVPGPSVQQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQELESLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRRKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVEKDPVKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEEESNEEEEEDDEEESESEAKSVKVKIKLNKKEEKGRDTGKGKKRPNRGKAKPVVSDFDSDEEQDENEQSEASGTDDE", "length": 1574, "header": "tr|A0A9J7FPL9-1|A0A9J7JJ57_CRIGR Computationally mapped isoform of Probable global transcription activator SNF2L2 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100770307 PE=3 SV=1 CANONICAL=A0A9J7JJ57-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57/entry#A0A9J7JIN8-1", "sequence": { "sequence": "MSTPTDPAAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSVSHPMSTMGSADFPQEAIHQMHKPMDGIHDKGIIDDAHCGSMKGASMRPPHPGMGPPQSPMDQHSQGYMSPHPSPLGAPEHVSSPISGGGPTPPQMPPSQPGPLIPGDLQAMNQPNRGPSPFSPVQLHQLRAQILAYKMLARGQPLPETLQLAVQGKRTLPGMQQQQQQQQQQQQQQQPQQPQQQPQQPQQQAQPQPQQQQPALVSYNRPSGPGQEMLMSGQSTPQKLSAPAPSGRPSPAPPAAAQPTATAVPGPSVQQPAPGQPSPVLQLQQKQSRISPIQKPQGLDPVEILQEREYRLQARIAHRIQELESLPGSLPPDLRTKATVELKALRLLNFQRQLRQEVVACMRRDTTLETALNSKAYKRSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSVAGKIQKLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVANLTNLVWEHKQAQAAKEKKKRRRRRKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMDRRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKRRRNVEKDPVKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDRCNVEKVPCNSQLEIEGNSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEEESNEEEEEDDEEESESEGKTLHLAPSTYRAISTAKSVKVKIKLNKKEEKGRDTGKGKKRPNRGKAKPVVSDFDSDEEQDENEQSEASGTDDE", "length": 1608, "header": "tr|A0A9J7JIN8-1|A0A9J7JIN8_CRIGR Computationally mapped isoform of Probable global transcription activator SNF2L2 isoform X8 OS=Cricetulus griseus OX=10029 GN=LOC100770307 PE=3 SV=1 CANONICAL=A0A9J7JJ57-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ57-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57/entry#A0A9J7JJ57-1", "sequence": { "sequence": 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"length": 1621, "header": "tr|A0A9J7JJ57-1|A0A9J7JJ57_CRIGR Isoform 1 of Probable global transcription activator SNF2L2 isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100770307 PE=3 SV=1 CANONICAL=A0A9J7JJ57-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JK76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57/entry#A0A9J7JK76-1", "sequence": { "sequence": "MAASCPSSSEPLLLKNHWRASLSLPCLCMHILFRENLMKRLAARCFAGLLILSPLTVISDSRPADSGKAIEDGNLEEMEEEVRLKKRKRRRNVEKDPVKEDVEKAKKRRGRPPAEKLSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNAQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEEESEEESNEEEEEDDEEESESEAKSVKVKIKLNKKEEKGRDTGKGKKRPNRGKAKPVVSDFDSDEEQDENEQSEASGTDDE", "length": 313, "header": "tr|A0A9J7JK76-1|A0A9J7JK76_CRIGR Computationally mapped isoform of Probable global transcription activator SNF2L2 isoform X13 OS=Cricetulus griseus OX=10029 GN=LOC100770307 PE=4 SV=1 CANONICAL=A0A9J7JJ57-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 144, "start_aa": "Thr", "end_pos": 144, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr144", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FJY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJY9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FJY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJY9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770307", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770307", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "nucleosome organization", "id": "GO:0034728", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034728", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" }, { "name": "chromatin remodeling", "id": "GO:0006338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" }, { "name": "transcription elongation by RNA polymerase II", "id": "GO:0006368", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" }, { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" }, { "name": "RSC-type complex", "id": "GO:0016586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016586", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1419, "end_pos": 1421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" }, { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H6T7-1", "G3H7V9-1", "G3HCT4-1", "G3HIC5-1", "G3HIL5-1", "A0A061IR73-1", "G3GXG9-1", "G3I8R9-1", "G3HH18-1", "A0A9J7FU33-1", "G3I2I1-1", "A0A9J7FTT2-1", "G3IEZ7-1", "G3HKQ8-1", "G3HMB1-1", "G3HCV0-1", "G3HX41-1", "G3I6K0-1", "G3HTL1-1", "G3HU77-1", "G3HAH5-1", "G3HJ88-1", "G3GSH5-1", "G3GY12-1", "G3I5T3-1", "G3I6L7-1", "G3H484-1", "G3IJD1-1", "G3I008-1", "A0A8C2M596-1", "G3IG24-1", "A0A9J7F876-1", "A0A9J7FI42-1", "A0A9J7G1N4-1", "A0A061IJA4-1", "A0A9J7FPD0-1", "A0A9J7G7V8-1", "A0A9J7JQY5-1", "A0A8C2MCA5-1", "A0A9J7H2D3-1", "A0A9J7G2T1-1", "G3HBU1-1", "G3HUZ6-1", "G3HWS4-1", "A0A9J7HCU3-1", "A0A3L7HMZ7-1", "A0A9J7K3T5-1", "A0A8C2MMI4-1", "A0A9J7GRQ0-1", "A0A8C2N055-1", "A0A8C2QHV1-1", "A0A8C2QM19-1", "A0A8C2M4F5-1", "A0A9J7FJ23-1", "A0A9J7FUH6-1", "A0A9J7G659-1", "A0A9J7K2R5-1", "A0A8C2MB35-1", "G3I478-1", "A0A9J7H1K5-1", "A0A8C2QH91-1", "A0A9J7JQ85-1", "A0A9J7K381-1", "A0A061HU45-1", "A0A061I456-1", "A0A061ICN7-1", "A0A061IKS3-1", "A0A3L7H9D4-1", "A0A9J7H2L4-1", "A0A8C2LZL3-1", "A0A8C2M796-1", "A0A8C2MCS3-1", "A0A8C2MPK3-1", "A0A8C2MQ86-1", "A0A3L7ILF9-1", "A0A3L7INC4-1", "A0A8C2LCW6-1", "A0A8C2LRD7-1", "A0A8C2LSK1-1", "A0A9J7JSD0-1", "P18279-1", "P48975-1", "A0A8C2MVH8-1", "A0A8C2MWE0-1", "A0A8C2MYM8-1", "A0A8C2N236-1", "A0A9J7FYM8-1", "A0A8C2QLX9-1", "A0A8C2QNE7-1", "A0A9J7F9W3-1", "A0A9J7JR19-1", "A0A9J7FPK3-1", "A0A9J7JMF4-1", "A0A9J7FV95-1", "A0A9J7FXI2-1", "A0A9J7G412-1", 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"evidence": [ { "id": "A0A061HU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HU45" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A061HU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HU45" } ] } ] }, { "uniprot_ac": "A0A061I456", "gene_name": "Ruvbl2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061I456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I456" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A061I456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I456" } ] } ] }, { "uniprot_ac": "A0A061ICN7", "gene_name": "Mtrex", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061ICN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ICN7" } ] }, { 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"ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8C2N236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N236" } ] } ] }, { "uniprot_ac": "A0A8C2N386", "gene_name": "Vcp", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] } ] }, { "uniprot_ac": "A0A8C2QH91", "gene_name": "Ino80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8C2QH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH91" } ] } ] }, { "uniprot_ac": "A0A8C2QHV1", "gene_name": "Ddx20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] } ] }, { "uniprot_ac": "A0A8C2QLX9", "gene_name": "Ddx52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] } ] }, { "uniprot_ac": "A0A8C2QM19", "gene_name": "Clpx", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] } ] }, { "uniprot_ac": "A0A8C2QNE7", "gene_name": "Eif4a3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] } ] }, { "uniprot_ac": "A0A9J7F1E5", "gene_name": "Hltf", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] } ] }, { "uniprot_ac": "A0A9J7F876", "gene_name": "Ddx11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] } ] }, { "uniprot_ac": "A0A9J7F9W3", "gene_name": "Zgrf1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] } ] }, { "uniprot_ac": "A0A9J7FCH5", "gene_name": "Mov10l1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] } ] }, { "uniprot_ac": "A0A9J7FI19", "gene_name": "Xrcc6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] } ] }, { "uniprot_ac": "A0A9J7FI42", "gene_name": "Fbh1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FJ37", "gene_name": "Mcm9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] } ] }, { "uniprot_ac": "A0A9J7FPD0", "gene_name": "Dhx32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] } ] }, { "uniprot_ac": "A0A9J7FPK3", "gene_name": "Twnk", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] } ] }, { "uniprot_ac": "A0A9J7FTT2", "gene_name": "Mcm5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] } ] }, { "uniprot_ac": "A0A9J7FU33", "gene_name": "Eif4a2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FU33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU33" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FU33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU33" } ] } ] }, { "uniprot_ac": "A0A9J7FUH6", "gene_name": "Polq", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] } ] }, { "uniprot_ac": "A0A9J7FV95", "gene_name": "LOC100751095", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A9J7FV95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV95" } ] } ] }, { "uniprot_ac": "A0A9J7FXI2", "gene_name": "Ddx10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] } ] }, { "uniprot_ac": "A0A9J7FYM8", "gene_name": "Ddx54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] } ] }, { "uniprot_ac": "A0A9J7G1N4", "gene_name": "Fancm", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] } ] }, { "uniprot_ac": "A0A9J7G2T1", "gene_name": "Dhx9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T1" } ] } ] }, { "uniprot_ac": "A0A9J7G412", "gene_name": "Helz2", "activity": [ { "ec_number": "3.1.13.1", "activity": "Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.1.13.1", "activity": "", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] } ] }, { "uniprot_ac": "A0A9J7G5W9", "gene_name": "Spata5l1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A9J7G5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W9" } ] } ] }, { "uniprot_ac": "A0A9J7G659", "gene_name": "Rtel1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A9J7G659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G659" } ] } ] }, { "uniprot_ac": "A0A9J7G6M1", "gene_name": "Mcm8", "activity": [ { "ec_number": "2.7.8.41", "activity": "a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H(+).", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "2.7.8.41", "activity": "", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] } ] }, { "uniprot_ac": "A0A9J7G7R5", "gene_name": "Setx", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G7R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R5" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G7R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R5" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7G7R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G7R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7R5" } ] } ] }, { "uniprot_ac": "A0A9J7G7V8", "gene_name": "Dhx35", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G7V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G7V8", "database": 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"activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GF88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF88" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GF88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF88" } ] } ] }, { "uniprot_ac": "A0A9J7GHR4", "gene_name": "Ercc2", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7GHR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR4" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7GHR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHR4" } ] } ] }, { "uniprot_ac": "A0A9J7GID0", "gene_name": "LOC103158905", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GID0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GID0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GID0" } ] } ] }, { "uniprot_ac": "A0A9J7GN75", "gene_name": "LOC100753355", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN75" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GN75" } ] } ] }, { "uniprot_ac": "A0A9J7GR00", "gene_name": "Entpd1", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 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"G3HAH5", "gene_name": "Dhx38", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3HAH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAH5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3HAH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAH5" } ] } ] }, { "uniprot_ac": "G3HBU1", "gene_name": "Rhot2", "activity": [ { "ec_number": "3.6.5.-", "activity": "", "evidence": [ { "id": "G3HBU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBU1" } ] } ] }, { "uniprot_ac": "G3HCS2", "gene_name": "Helz", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3HCS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCS2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3HCS2", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3I5T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5T3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3I5T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5T3" } ] } ] }, { "uniprot_ac": "G3I6K0", "gene_name": "Ddx23", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "G3I6K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I6K0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3I6K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I6K0" } ] } ] }, { "uniprot_ac": "G3I6L7", "gene_name": "Brip1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' 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ADP + phosphate + H(+).", "evidence": [ { "id": "G3IJD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IJD1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "G3IJD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IJD1" } ] } ] }, { "uniprot_ac": "O35501", "gene_name": "HSPA9", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "O35501", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O35501" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "O35501", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O35501" } ] } ] }, { "uniprot_ac": "P18279", "gene_name": "TCP1", "activity": [ { "ec_number": "3.6.1.-", "activity": "", "evidence": [ { "id": "P18279", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P18279" } ] } ] }, { "uniprot_ac": "P18708", "gene_name": "NSF", "activity": [ { 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"ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "Q60452", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q60452" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JJ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 1434, "end_pos": 1504, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JJ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" }, { "id": "PS51204", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51204" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HSA", "eco_id": "ECO_0000259", "start_pos": 438, "end_pos": 510, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JJ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 738, "end_pos": 903, "start_aa": "Val", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JJ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" }, { "id": "PS51194", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51194" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase C-terminal", "eco_id": "ECO_0000259", "start_pos": 1056, "end_pos": 1218, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JJ57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ57" }, { "id": "PS51666", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51666" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "QLQ", "eco_id": "ECO_0000259", "start_pos": 173, "end_pos": 208, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 144 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1419, "end_pos": 1421 }, { "start_pos": 541, "end_pos": 543 }, { "start_pos": 723, "end_pos": 725 }, { "start_pos": 789, "end_pos": 791 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", 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"count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JJ70-1", "uniprot_ac": "A0A9J7JJ70", "uniprot_id": "A0A9J7JJ70_CRIGR", "mass": { "chemical_mass": 130851.0, "monoisotopic_mass": 130851.0 }, "refseq": { "ac": "XP_027262315", "name": "structural maintenance of chromosomes protein 5 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262315" }, "gene_names": [ { "name": "Smc5", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ] }, { "name": "Smc5", "type": "synonym", "evidence": [ { "id": "XP_027262315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262315" } ] } ], "protein_names": [ { "name": "Structural maintenance of chromosomes protein 5", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ70", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70/entry#names_and_taxonomy" } ] }, { "name": "structural maintenance of chromosomes protein 5 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_027262315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262315" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262315" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Smc5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70", "locus": {} } ], "crossref": [ { "id": "A0A9J7JJ70", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JJ70", "database": "AlphaFoldDB", "categories": [] }, { "id": "100758700", "url": "https://www.ncbi.nlm.nih.gov/gene/100758700", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038729", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038729", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758700", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758700", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N321", "url": "https://www.orthodb.org/?gene=A0A8C2N321", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JJ70", "url": "https://www.orthodb.org/?gene=A0A9J7JJ70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45916", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45916", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45916:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45916:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262315", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262315", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N321", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N321", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N321-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N321-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FK08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FK08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FK08-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FK08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FKN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FKN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ70-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATPTGKAATLNPQASKRVLPRDASSEVPGKRKNPNPTSTLPRPSGPFVEGSIVRIAMENFLTYDICEVSPGPHLNMIIGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSKGLVEIELFRTSGNLVITREIDVIKNQSFWFINKKPVTQKIVEEQVAALNIQVGNLCQFLPQDKVGEFAKLSKIELLEATEKSIGPPEMHRYHCELKNFREKEKQLETSCKEKTEYLEKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEGVKLVRDRVKEEVRKLKEGQIPMTRRIEEIERQRRTLETRIKEKATEIKEASQKCKQRQDIIERKDRHIKELQQALTVKQNEEHDRQKRISNTRRMIEDLQNELRTAENCENLQPQIDAITNDLRRVQEEKGLCEGEIIDKQREKEMLEKQKRSVSDHIIRFDNLMNQKEDKLRQRYRDTYDAVLWLRNNRDRFKQRVCEPIMLTINMKDNKNAKYVENHISSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIAPKISYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTERTREKIERVIQETRLKQIYTAEEKYVLKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLKEINRKLEAVESGLVALRDTNKHLELKDNELRLKKKELLERKTKKRQLEQKISSKLGSIRLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTGLVKICTSLHIQKVNLILQNTTVISEKNKLEADYMASSSQLRVTEQQFIELDDNRQRLLQKCKELMRRARQVCNLSADQAVPQEFQTAPHILDPFYQFSKYPPFQMDTAPHPPWYAFQDLPNTLDEIDALLTEERSRASCFTGLNPTVVEEYTKREIEIQQLTEELKGKRVELDEYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEPNRWNLKAFQRRRRRITFTQPSQ", "length": 1115, "header": "tr|A0A9J7JJ70-1|A0A9J7JJ70_CRIGR Isoform 1 of Structural maintenance of chromosomes protein 5 OS=Cricetulus griseus OX=10029 GN=Smc5 PE=3 SV=1 CANONICAL=A0A9J7JJ70-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N321-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70/entry#A0A8C2N321-1", "sequence": { "sequence": "MATPTGKAATLNPQASKRVLPRDASSEVPGKRKNPNPTSTLPRPSGPFVEGSIVRIAMENFLTYDICEVSPGPHLNMIIGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSKGLVEIELFRTSGNLVITREIDVIKNQSFWFINKKPVTQKIVEEQVAALNIQVGNLCQFLPQDKVGEFAKLSKIELLEATEKSIGPPEMHRYHCELKNFREKEKQLETSCKEKTEYLEKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEGVKLVRDRVKEEVRKLKEGQIPMTRRIEEIERQRRTLETRIKEKATEIKEASQKCKQRQDIIERKDRHIKELQQALTVKQNEEHDRQKRISNTRRMIEDLQNELRTAENCENLQPQIDAITNDLRRVQEEKGLCEGEIIDKQREKEMLEKQKRSVSDHIIRFDNLMNQKEDKLRQRYRDTYDAVLWLRNNRDRFKQRVCEPIMLTINMKDNKNAKYVENHISSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIAPKISYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTERTREKIERVIQETRLKQIYTAEEKYVLKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLKEINRKLEAVESGLVALRDTNKHLELKDNELRLKKKELLERKTKKRQLEQKISSKLGSIRLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTGLVKICTSLHIQKVNLILQNTTVISEKNKLEADYMASSSQLRVTEQQFIELDDNRQRLLQKCKELMRRARQVCNLSADQAVPQEFQTAFQDLPNTLDEIDALLTEERSRASCFTGLNPTVVEEYTKREIEIQQLTEELKGKRVELDEYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEPNRWNLKAFQRRRRRITFTQPSQ", "length": 1087, "header": "tr|A0A8C2N321-1|A0A8C2N321_CRIGR Computationally mapped isoform of Structural maintenance of chromosomes protein 5 OS=Cricetulus griseus OX=10029 GN=Smc5 PE=3 SV=1 CANONICAL=A0A9J7JJ70-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FK08-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70/entry#A0A9J7FK08-1", "sequence": { "sequence": "MATPTGKAATLNPQASKRVLPRDASSEVPGKRKNPNPTSTLPRPSGPFVEGSIVRIAMENFLTYDICEVSPGPHLNMIIGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSKGLVEIELFRTSGNLVITREIDVIKNQSFWFINKKPVTQKIVEEQVAALNIQVGNLCQFLPQDKVGEFAKLSKIELLEATEKSIGPPEMHRYHCELKNFREKEKQLETSCKEKTEYLEKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEGVKLVRDRVKEEVRKLKEGQIPMTRRIEEIERQRRTLETRIKEKATEIKEASQKCKQRQDIIERKDRHIKELQQALTVKQNEEHDRQKRISNTRRMIEDLQNELRTAENCENLQPQIDAITNDLRRVQEEKGLCEGEIIDKQREKEMLEKQKRSVSDHIIRFDNLMNQKEDKLRQRYRDTYDAVLWLRNNRDRFKQRVCEPIMLTINMKDNKNAKYVENHISSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIAPKISYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTERTREKIERVIQETRLKQIYTAEEKYVLKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLKEINRKLEAVESGLVALRDTNKHLELKDNELRLKKKELLERKTKKRQLEQKISSKLGSIRLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTGLVKICTSLHIQKVNLILQNTTVISEKNKLEADYMASSSQLRVTEQQFIELDDNRQRLLQKCKELMRRARQVCNLSADQAVPQEFQTAPHILDPFYQFSKYPPFQMDTAPHPPWLSKIFQTHWMKLMHY", "length": 883, "header": "tr|A0A9J7FK08-1|A0A9J7JJ70_CRIGR Computationally mapped isoform of Structural maintenance of chromosomes protein 5 OS=Cricetulus griseus OX=10029 GN=Smc5 PE=3 SV=1 CANONICAL=A0A9J7JJ70-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FKN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70/entry#A0A9J7FKN8-1", "sequence": { "sequence": 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"length": 1102, "header": "tr|A0A9J7FKN8-1|A0A9J7JJ70_CRIGR Computationally mapped isoform of Structural maintenance of chromosomes protein 5 OS=Cricetulus griseus OX=10029 GN=Smc5 PE=3 SV=1 CANONICAL=A0A9J7JJ70-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70/entry#A0A9J7JIP8-1", "sequence": { "sequence": 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"length": 1112, "header": "tr|A0A9J7JIP8-1|A0A9J7JIP8_CRIGR Computationally mapped isoform of Structural maintenance of chromosomes protein 5 OS=Cricetulus griseus OX=10029 GN=Smc5 PE=3 SV=1 CANONICAL=A0A9J7JJ70-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ70-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70/entry#A0A9J7JJ70-1", "sequence": { "sequence": "MATPTGKAATLNPQASKRVLPRDASSEVPGKRKNPNPTSTLPRPSGPFVEGSIVRIAMENFLTYDICEVSPGPHLNMIIGANGTGKSSIVCAICLGLAGKPAFMGRADKVGFFVKRGCSKGLVEIELFRTSGNLVITREIDVIKNQSFWFINKKPVTQKIVEEQVAALNIQVGNLCQFLPQDKVGEFAKLSKIELLEATEKSIGPPEMHRYHCELKNFREKEKQLETSCKEKTEYLEKMVQRNERYKQDVERFYERKRHLDLIEMLEAKRPWVEYENVRQEYEGVKLVRDRVKEEVRKLKEGQIPMTRRIEEIERQRRTLETRIKEKATEIKEASQKCKQRQDIIERKDRHIKELQQALTVKQNEEHDRQKRISNTRRMIEDLQNELRTAENCENLQPQIDAITNDLRRVQEEKGLCEGEIIDKQREKEMLEKQKRSVSDHIIRFDNLMNQKEDKLRQRYRDTYDAVLWLRNNRDRFKQRVCEPIMLTINMKDNKNAKYVENHISSNDLRAFVFESQEDMEVFLKEVRDNKKLRVNAVIAPKISYADKAPSRSLNELKQYGFFSYLRELFDAPDPVMSYLCCQYHIHEVPVGTERTREKIERVIQETRLKQIYTAEEKYVLKTSFYSNKVISSNTSLKVAQFLTVTVDLEQRRHLEEQLKEINRKLEAVESGLVALRDTNKHLELKDNELRLKKKELLERKTKKRQLEQKISSKLGSIRLMEQDTCNLEEEERKASTKIKEINVQKAKLVTELTGLVKICTSLHIQKVNLILQNTTVISEKNKLEADYMASSSQLRVTEQQFIELDDNRQRLLQKCKELMRRARQVCNLSADQAVPQEFQTAPHILDPFYQFSKYPPFQMDTAPHPPWYAFQDLPNTLDEIDALLTEERSRASCFTGLNPTVVEEYTKREIEIQQLTEELKGKRVELDEYRENISQVKERWLNPLKELVEKINEKFSNFFSSMQCAGEVDLHTENEEDYDKYGIRIRVKFRSSTQLHELTPHHQSGGERSVSTMLYLMALQELNRCPFRVVDEINQGMDPINERRVFEMVVNTACKENTSQYFFITPKLLQNLPYSEKMTVLFVYNGPHMLEPNRWNLKAFQRRRRRITFTQPSQ", "length": 1115, "header": "tr|A0A9J7JJ70-1|A0A9J7JJ70_CRIGR Isoform 1 of Structural maintenance of chromosomes protein 5 OS=Cricetulus griseus OX=10029 GN=Smc5 PE=3 SV=1 CANONICAL=A0A9J7JJ70-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FK08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FK08" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FK08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FK08" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758700", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758700", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ], "pmid": "" }, { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ], "pmid": "" }, { "name": "Smc5-Smc6 complex", "id": "GO:0030915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030915", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ], "pmid": "" }, { "name": "PML body", "id": "GO:0016605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ70" } ], "pmid": "" }, { "name": "chromosome organization", "id": "GO:0051276", "url": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JIQ8-1", "uniprot_ac": "A0A9J7JIQ8", "uniprot_id": "A0A9J7JIQ8_CRIGR", "mass": { "chemical_mass": 23038.0, "monoisotopic_mass": 23038.0 }, "refseq": { "ac": "XP_027262354", "name": "nicotinamide riboside kinase 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262354" }, "gene_names": [ { "name": "LOC100751894", "type": "recommended", "evidence": [ { "id": "A0A9J7JIQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ8" } ] }, { "name": "LOC100751894", "type": "synonym", "evidence": [ { "id": "XP_027262354", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262354" } ] } ], "protein_names": [ { "name": "Nicotinamide riboside kinase 1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7JIQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ8/entry#names_and_taxonomy" } ] }, { "name": "nicotinamide riboside kinase 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027262354", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262354" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. 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"MTTANCGAHDELDFKLVFGEDGAPAPVSQVSRPADLEPDDCASIYIFNVDPPPSTLNSSLGLPHHGLLQSHSSVLSPSFQLQGHKNYEGTGDISESKYSPLGGSKPFECPSIQITSISPNCHQGTDVHEDDLQINDPEREYLERPSRDHLYLPLEPSYRESSFSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEDSWQQQYGPGHSLSPRQSPCHSPRSSITDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLTASVHTGSGLGPAPFPFQYCVETDIPLKTRKTSEDQAVILSGKLEICSDDQGSLSPSRETSVDDALGSPYALKKDSSGDQFLSVPSPFTWSKPKPGHTPVFRTSSLPPLDWPLPTHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYSEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMIVTGSNFLPESKIIFLEKGQDGRPHWEAEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEQREDTDLSSVPSLPVPHSAQTQRPSSVTGHPHDSVLSASRSLICPIQPAYASMITSSHLPQLQCGDEGASKEQHIIPSSVMHQPFQVTSTSPMGSSYQSIQTNMYNGPTCLPMNPASSQEFDPVLFQQDAALSTLVNLGCQPLSPIPFHSSNSDATGHLLAHSPHSVQTPPHLQSMGYHCSNTGQRSLSSPVADQVTGQPSSHLQPITYCPSHPGSAPAASPAASHPLANSPLSGPSSSQLQSMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQEGLSALSSLVCHSLCDPASFPPGGAAVSIKPEPEDQEPNFATIGLQDITLDDVVMLSSLTQTSLCLTWNTSHQVQQRNGLITVSSHVQFLSGESRGERDNWERHVPDFCFPRPRAAMILSHGVLTV", "length": 1109, "header": "tr|A0A9J7JJT5-1|A0A9J7JJT5_CRIGR Isoform 1 of Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Nfatc3 PE=4 SV=1 CANONICAL=A0A9J7JJT5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QCQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5/entry#A0A8C2QCQ9-1", "sequence": { "sequence": "MTTANCGAHDELDFKLVFGEDGAPAPVSQVSRPADLEPDDCASIYIFNVDPPPSTLNSSLGLPHHGLLQSHSSVLSPSFQLQGHKNYEGTGDISESKYSPLGGSKPFECPSIQITSISPNCHQGTDVHEDDLQINDPEREYLERPSRDHLYLPLEPSYRESSFSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEDSWQQQYGPGHSLSPRQSPCHSPRSSITDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLTASVHTGSGLGPAPFPFQYCVETDIPLKTRKTSEDQAVILSGKLEICSDDQGSLSPSRETSVDDALGSPYALKKDSSGDQFLSVPSPFTWSKPKPGHTPVFRTSSLPPLDWPLPTHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYSEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMIVTGSNFLPESKIIFLEKGQDGRPHWEAEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEQREDTDLSSVPSLPVPHSAQTQRPSSVTGHPHDSVLSASRSLICPIQPAYASMITSSHLPQLQCGDEGASKEQHIIPSSVMHQPFQVTSTSPMGSSYQSIQTNMYNGPTCLPMNPASSQEFDPVLFQQDAALSTLVNLGCQPLSPIPFHSSNSDATGHLLAHSPHSVQTPPHLQSMGYHCSNTGQRSLSSPVADQVTGQPSSHLQPITYCPSHPGSAPAASPAASHPLANSPLSGPSSSQLQSMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQEGLSALSSLVCHSLCDPASFPPGGAAVSIKPEPEDQEPNFATIGLQDITLDDVNEIIGRDMSQISVSQGPEPQ", "length": 1056, "header": "tr|A0A8C2QCQ9-1|A0A8C2QCQ9_CRIGR Computationally mapped isoform of Nuclear factor of activated T-cells, cytoplasmic 3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Nfatc3 PE=4 SV=1 CANONICAL=A0A9J7JJT5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FKS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5/entry#A0A9J7FKS3-1", "sequence": { "sequence": "MTTANCGAHDELDFKLVFGEDGAPAPVSQVSRPADLEPDDCASIYIFNVDPPPSTLNSSLGLPHHGLLQSHSSVLSPSFQLQGHKNYEGTGDISESKYSPLGGSKPFECPSIQITSISPNCHQGTDVHEDDLQINDPEREYLERPSRDHLYLPLEPSYRESSFSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEDSWQQQYGPGHSLSPRQSPCHSPRSSITDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLTASVHTGSGLGPAPFPFQYCVETDIPLKTRKTSEDQAVILSGKLEICSDDQGSLSPSRETSVDDALGSPYALKKDSSGDQFLSVPSPFTWSKPKPGHTPVFRTSSLPPLDWPLPTHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYSEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMIVTGSNFLPESKIIFLEKGQDGRPHWEAEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEQREDTDLSSVPSLPVPHSAQTQRPSSVTGHPHDSVLSASRSLICPIQPAYASMITSSHLPQLQCGDEGASKEQHIIPSSVMHQPFQVTSTSPMGSSYQSIQTNMYNGPTCLPMNPASSQEFDPVLFQQDAALSTLVNLGCQPLSPIPFHSSNSDATGHLLAHSPHSVQTPPHLQSMGYHCSNTGQRSLSSPVADQVTGQPSSHLQPITYCPSHPGSAPAASPAASHPLANSPLSGPSSSQLQSMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQEGLSALSSLVCHSLCDPASFPPGGAAVSIKPEPEDQEPNFATIGLQDITLDDDQFMSDLEHQPSGSTEKWPNHSELSCPVPFWRI", "length": 1068, "header": "tr|A0A9J7FKS3-1|A0A9J7JJT5_CRIGR Computationally mapped isoform of Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Nfatc3 PE=4 SV=1 CANONICAL=A0A9J7JJT5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FMW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5/entry#A0A9J7FMW0-1", "sequence": { "sequence": "MTTANCGAHDELDFKLVFGEDGAPAPVSQVSRPADPPPSTLNSSLGLPHHGLLQSHSSVLSPSFQLQGHKNYEGTGDISESKYSPLGGSKPFECPSIQITSISPNCHQGTDVHEDDLQINDPEREYLERPSRDHLYLPLEPSYRESSFSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEDSWQQQYGPGHSLSPRQSPCHSPRSSITDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLTASVHTGSGLGPAPFPFQYCVETDIPLKTRKTSEDQAVILSGKLEICSDDQGSLSPSRETSVDDALGSPYALKKDSSGDQFLSVPSPFTWSKPKPGHTPVFRTSSLPPLDWPLPTHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYSEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMIVTGSNFLPESKIIFLEKGQDGRPHWEAEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEQREDTDLSSVPSLPVPHSAQTQRPSSVTGHPHDSVLSASRSLICPIQPAYASMITSSHLPQLQCGDEGASKEQHIIPSSVMHQPFQVTSTSPMGSSYQSIQTNMYNGPTCLPMNPASSQEFDPVLFQQDAALSTLVNLGCQPLSPIPFHSSNSDATGHLLAHSPHSVQTPPHLQSMGYHCSNTGQRSLSSPVADQVTGQPSSHLQPITYCPSHPGSAPAASPAASHPLANSPLSGPSSSQLQSMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQEGLSALSSLVCHSLCDPASFPPGGAAVSIKPEPEDQEPNFATIGLQDITLDDVVMLSSLTQTSLCLTWNTSHQVQQRNGLITVSSHVQFLSGESRGERDNWERHVPDFCFPRPRAAMILSHGVLTV", "length": 1094, "header": "tr|A0A9J7FMW0-1|A0A9J7JJT5_CRIGR Computationally mapped isoform of Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Nfatc3 PE=4 SV=1 CANONICAL=A0A9J7JJT5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5/entry#A0A9J7JJT5-1", "sequence": { "sequence": "MTTANCGAHDELDFKLVFGEDGAPAPVSQVSRPADLEPDDCASIYIFNVDPPPSTLNSSLGLPHHGLLQSHSSVLSPSFQLQGHKNYEGTGDISESKYSPLGGSKPFECPSIQITSISPNCHQGTDVHEDDLQINDPEREYLERPSRDHLYLPLEPSYRESSFSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEDSWQQQYGPGHSLSPRQSPCHSPRSSITDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLTASVHTGSGLGPAPFPFQYCVETDIPLKTRKTSEDQAVILSGKLEICSDDQGSLSPSRETSVDDALGSPYALKKDSSGDQFLSVPSPFTWSKPKPGHTPVFRTSSLPPLDWPLPTHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYSEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMIVTGSNFLPESKIIFLEKGQDGRPHWEAEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEQREDTDLSSVPSLPVPHSAQTQRPSSVTGHPHDSVLSASRSLICPIQPAYASMITSSHLPQLQCGDEGASKEQHIIPSSVMHQPFQVTSTSPMGSSYQSIQTNMYNGPTCLPMNPASSQEFDPVLFQQDAALSTLVNLGCQPLSPIPFHSSNSDATGHLLAHSPHSVQTPPHLQSMGYHCSNTGQRSLSSPVADQVTGQPSSHLQPITYCPSHPGSAPAASPAASHPLANSPLSGPSSSQLQSMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQEGLSALSSLVCHSLCDPASFPPGGAAVSIKPEPEDQEPNFATIGLQDITLDDVVMLSSLTQTSLCLTWNTSHQVQQRNGLITVSSHVQFLSGESRGERDNWERHVPDFCFPRPRAAMILSHGVLTV", "length": 1109, "header": "tr|A0A9J7JJT5-1|A0A9J7JJT5_CRIGR Isoform 1 of Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Nfatc3 PE=4 SV=1 CANONICAL=A0A9J7JJT5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FKS3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKS3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FKS3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKS3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760989", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760989", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5" } ], "pmid": "" }, { "name": "calcineurin-NFAT signaling cascade", "id": "GO:0033173", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033173", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1052, "end_pos": 1054, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JJT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJT5" }, { "id": "PS50254", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50254" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RHD", "eco_id": "ECO_0000259", "start_pos": 416, "end_pos": 597, "start_aa": "Ser", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1052, "end_pos": 1054 }, { "start_pos": 531, "end_pos": 533 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260183", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260183" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dsg3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ9", "locus": {} } ], "crossref": [ { "id": "A0A9J7JIQ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JIQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"header": "tr|A0A9J7FKX5-1|A0A9J7JIQ9_CRIGR Computationally mapped isoform of Desmoglein-3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dsg3 PE=4 SV=1 CANONICAL=A0A9J7JIQ9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ9/entry#A0A9J7JIQ9-1", "sequence": { "sequence": "MTCPFPRVLGPLALLMVVLLVHGELQIEPGGQHREDGTAVQQVKRRYKREWVKFAKPCREREDNSKRNPIAKITSDFQATQKITYRISGVGIDQPPFGIFVVDPNSGDINITAIVDREETPSFLITCRALNARGQDVERPLILTVKILDVNDNAPIFSQTIFKGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIISQEPAGMPMFLISRNTGEVRTLTSSLDREQVSSYHLVVSGADNDGRGLSTQCECSIKVKDVNDNFPLLTDSQYSARIEENTLNSELLRFQVTDWDEEYTDNWLAVYFFTSGNEGNWFEIETDPRTNEGILKVVKALDYEQMQSTQFSIAVRNKAEFHQSVISQYRVQSTPVIIQVINVREGISFRPPSKTFIVPKGVSTNKLAGYILGTYQATDEDTGKAASSVRYVLGRNDGGLLVIDSKTAQIKFVKNIDRDSTFIVNKTISAEVLAIDENTGKTSTGTVHVEVPSFSENCPSVVLEKEEICSSSPSVVVSVRTLERDKYTGPYTVSLEEQPLKLPVMWNIGMMNATSALLRAQQQMSPGVYSVPVTVKDNEGRQCDTPEILTLTVCQCDDRSMCRAPTPSRGPIIYRESSWRLGPAAIGLILLGLLMLLLAPLLLLTCDCGAGPIGGGAETGGFIPVPDGSEGTIHQWGIEGAQPEDKEITNICVPPITTNGADFMESSEVCTNTYAGGTVVEGASGMEMTTKLGAATGSAATGALGPCSLAHSGTMRTRHSTGGTLKDYVAAPVNMTFLGSYFSQKSFAYAEEEGEREVNDCLLIYDDEGEDAAPCSPALSSCSFIADDLDDSFLDSLGPKFKKLGEICLGIDDEAKQAKPGPKGSGSGADICARPTEVPQSGSQRYQTLPGSLEVPQSGSQRHQTLSGGQDASVVFTSGSVHPAIAIPDPLQLGNYLLTETHSTSGSFVQPTTATFEPHLTQNVTVTERVICPLPSVSGSIVAPTELRGSYNMLYTKETCSHL", "length": 997, "header": "tr|A0A9J7JIQ9-1|A0A9J7JIQ9_CRIGR Isoform 1 of Desmoglein-3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dsg3 PE=4 SV=1 CANONICAL=A0A9J7JIQ9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 600, "start_aa": "Thr", "end_pos": 600, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr600", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FKX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKX5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FKX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKX5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761782", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761782", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ9" } ], "pmid": "" }, { "name": "desmosome", "id": "GO:0030057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030057", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JJ17-1", "uniprot_ac": "A0A9J7JJ17", "uniprot_id": "A0A9J7JJ17_CRIGR", "mass": { "chemical_mass": 176362.0, "monoisotopic_mass": 176362.0 }, "refseq": { "ac": "XP_027260594", "name": "probable methyltransferase TARBP1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260594" }, "gene_names": [ { "name": "Tarbp1", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17" } ] }, { "name": "Tarbp1", "type": "synonym", "evidence": [ { "id": "XP_027260594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260594" } ] } ], "protein_names": [ { "name": "tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.34", "type": "synonym", "evidence": [ { "id": "A0A9J7JJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17/entry#names_and_taxonomy" } ] }, { "name": "TAR RNA-binding protein 1", "type": "synonym", "evidence": [ { "id": "A0A9J7JJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17/entry#names_and_taxonomy" } ] }, { "name": "probable methyltransferase TARBP1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027260594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260594" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260594" } ] }, { "annotation": "S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in a subset of tRNA. Selectively mediates Gm18 methylation of tRNAGln-TTG/CTG and tRNASer-TGA/GCT. Gm18 modification can enhance the stability of modified tRNAs.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FL78", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL78#function" }, { "database": "UniProtKB", "id": "ARBA00093361", "url": "https://www.uniprot.org/uniprotkb/ARBA00093361#function" }, { "database": "UniProtKB", "id": "A0A9J7JJ17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17#function" }, { "database": "UniProtKB", "id": "A0A9J7GUH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUH9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tarbp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17", "locus": {} } ], "crossref": [ { "id": "cd18091", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18091", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770970", "url": "https://www.ncbi.nlm.nih.gov/gene/100770970", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001537", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001537", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029026", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029026", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770970", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770970", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JJ17", "url": "https://www.orthodb.org/?gene=A0A9J7JJ17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12029", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12029", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12029:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12029:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25050", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25050", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260594", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20077", "url": "https://www.rhea-db.org/rhea/20077", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FL78", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FL78-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ17-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERVLADALLAQSREPCALLGTLCGGEATAERAETLRLVLQRLEERGVGAGALAEAAHEVAKGHLVPLLKASPGGGPAGPRVLRAASAALRSCARLAGPELAVALAEDALRELPRVPAVELLAAVAPCLRALEDAPLLRRLARASVELALAGDAPPAVGARLLPALSLSAEPALREAWDTLASSGPEAEGRTGPELLVLSALAEKLLSADARHADLDARLRGSFWRTVQAGLGRAQDALTRKRARYLLQRAVQLSAELAMDCYCGPQDTLGPSLFWWSEKKKDELLKFWENYILIMEVLEGNQIHVIKPVLPKLNSLFEYAVSEENGCWLFHPSWHMCIYKRMFESENKILTKEGVIHFLELYEVKSLPYSPELSEFITGPLMDALSESCLYSRSPGQLLGSGSPLGLKLQKFLVTYVSLLPEETKSHFLLKFIQRMADRHWCAVPILFLSKALASLPRCKALGGEGLLALRDVLQCTMITHQVLLRGAAQCYLLQTAMHLVDVEKVSLSDISAFLVSLRQEESLGRGTMLWTELCDWLRVNERYFRQSLIGGSDGQETSLNAYVKKLVQEFVKSPGWERESCFMPDWLEARLTSLMVLLAVDVEGMKTQFREKQRTQNVLRIFLDPLLDALGKLATNAYMPLLRTDRCLQLLARLLHSCVPRGSSGQDDEVSSVLQTSIMSVADSVSQFVLRRLTMNELQSVADLDRCQLYLKVLAELTSLQVKQGWKAGNPISRVISPLKNACIHHLQEAEDGEEPTLGHQVQRAVSMATLAALCEAVDQHPVLQLDAEPMDRFLSTLPLNQMLQKPRSEEQNGCVHPLENGSVFEESSSSQGWGKIAAQYLHDQWVCLSFLLRKHYPLIPTTESDRLECFLPAVEMPVQTLRSALDVLTVLPAGCILPVFRCMEVLVPKLLTSDESLCIESFDMAWKIISSLSNTQLTFWPNLKAFIHFVFNNEILTIAAKLKGQGYFKIKEIMCKIIEMSSIKTGVFNILICHCCQSWIAAACGVSHSSLFSSAKDYSELVLEACVFGTVFRRDQRLIQDVQTFIENLGQDCAANIIIENTKREDYYVRICAVKFLCLLDGSNISHKLFIEDLAIQLLDKDESTSRSRTRYHENSLQHRVKNRAWQTLLVLFPRFDQNFLNGIIDKIFHAGFTNNQASIKYFIEWIIILILHKFPQFLPKFWDCFSYGEEKLKTSICTFLSVLSHLDIIIQNIPEKRLVLKQALTIALQWCLSHNFSVRLYALVALKKAWQLCKALKFEECDAWTTVIECSLSQAESMHGAGNARKNWQRIQDHFFFSTFHPLKDYCLETIFYTLPRLSGITEEEWITLDKFASFTDIPSNTGSHWYLSGTALGELSPGDWSQQDRGYTLGEAESQSEWADVQKKIIPWGHKALESDLELMFQDRAAKLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGAAVLVVGSLQCVSDRQFQHLSVSAEQWLPLVEVRPAQLTDYLQQKKAEGYTVIGVEQTAQSSDLAQYRFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLGCAGLAS", "length": 1577, "header": "tr|A0A9J7JJ17-1|A0A9J7JJ17_CRIGR Isoform 1 of tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1 OS=Cricetulus griseus OX=10029 GN=Tarbp1 PE=3 SV=1 CANONICAL=A0A9J7JJ17-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FL78-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17/entry#A0A9J7FL78-1", "sequence": { "sequence": "MEVLEGNQIHVIKPVLPKLNSLFEYAVSEENGCWLFHPSWHMCIYKRMFESENKILTKEGVIHFLELYEVKSLPYSPELSEFITGPLMDALSESCLYSRSPGQLLGSGSPLGLKLQKFLVTYVSLLPEETKSHFLLKFIQRMADRHWCAVPILFLSKALASLPRCKALGGEGLLALRDVLQCTMITHQVLLRGAAQCYLLQTAMHLVDVEKVSLSDISAFLVSLRQEESLGRGTMLWTELCDWLRVNERYFRQSLIGGSDGQETSLNAYVKKLVQEFVKSPGWERESCFMPDWLEARLTSLMVLLAVDVEGMKTQFREKQRTQNVLRIFLDPLLDALGKLATNAYMPLLRTDRCLQLLARLLHSCVPRGSSGQDDEVSSVLQTSIMSVADSVSQFVLRRLTMNELQSVADLDRCQLYLKVLAELTSLQVKQGWKAGNPISRVISPLKNACIHHLQEAEDGEEPTLGHQVQRAVSMATLAALCEAVDQHPVLQLDAEPMDRFLSTLPLNQMLQKPRSEEQNGCVHPLENGSVFEESSSSQGWGKIAAQYLHDQWVCLSFLLRKHYPLIPTTESDRLECFLPAVEMPVQTLRSALDVLTVLPAGCILPVFRCMEVLVPKLLTSDESLCIESFDMAWKIISSLSNTQLTFWPNLKAFIHFVFNNEILTIAAKLKGQGYFKIKEIMCKIIEMSSIKTGVFNILICHCCQSWIAAACGVSHSSLFSSAKDYSELVLEACVFGTVFRRDQRLIQDVQTFIENLGQDCAANIIIENTKREDYYVRICAVKFLCLLDGSNISHKLFIEDLAIQLLDKDESTSRSRTRYHENSLQHRVKNRAWQTLLVLFPRFDQNFLNGIIDKIFHAGFTNNQASIKYFIEWIIILILHKFPQFLPKFWDCFSYGEEKLKTSICTFLSVLSHLDIIIQNIPEKRLVLKQALTIALQWCLSHNFSVRLYALVALKKAWQLCKALKFEECDAWTTVIECSLSQAESMHGAGNARKNWQRIQDHFFFSTFHPLKDYCLETIFYTLPRLSGITEEEWITLDKFASFTDIPSNTGSHWYLSGTALGELSPGDWSQQDRGYTLGEAESQSEWADVQKKIIPWGHKALESDLELMFQDRAAKLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGAAVLVVGSLQCVSDRQFQHLSVSAEQWLPLVEVRPAQLTDYLQQKKAEGYTVIGVEQTAQSSDLAQYRFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLGCAGLAS", "length": 1282, "header": "tr|A0A9J7FL78-1|A0A9J7JJ17_CRIGR Computationally mapped isoform of tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1 OS=Cricetulus griseus OX=10029 GN=Tarbp1 PE=3 SV=1 CANONICAL=A0A9J7JJ17-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FLG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17/entry#A0A9J7FLG3-1", "sequence": { "sequence": "MERVLADALLAQSREPCALLGTLCGGEATAERAETLRLVLQRLEERGVGAGALAEAAHEVAKGHLVPLLKASPGGGPAGPRVLRAASAALRSCARLAGPELAVALAEDALRELPRVPAVELLAAVAPCLRALEDAPLLRRLARASVELALAGDAPPAVGARLLPALSLSAEPALREAWDTLASSGPEAEGRTGPELLVLSALAEKLLSADARHADLDARLRGSFWRTVQAGLGRAQDALTRKRARYLLQRAVQLSAELAMDCYCGPQDTLGPSLFWWSEKKKDELLKFWENYILIMEVLEGNQIHVIKPVLPKLNSLFEYAVSEENGCWLFHPSWHMCIYKRMFESENKILTKEGVIHFLELYEVKSLPYSPELSEFITGPLMDALSESCLYSRSPGQLLGSGSPLGLKLQKFLVTYVSLLPEETKSHFLLKFIQRMADRHWCAVPILFLSKALASLPRCKALGGEGLLALRDVLQCTMITHQVLLRGAAQCYLLQTAMHLVDVEKVSLSDISAFLVSLRQEESLGRGTMLWTELCDWLRVNERYFRQSLIGGSDGQETSLNAYVKKLVQEFVKSPGWERESCFMPDWLEARLTSLMVLLAVDVEGMKTQFREKQRTQNVLRIFLDPLLDALGKLATNAYMPLLRTDRCLQLLARLLHSCVPRGSSGQDDEVSSVLQTSIMSVADSVSQFVLRRLTMNELQSVADLDRCQLYLKVLAELTSLQVKQGWKAGNPISRVISPLKNACIHHLQEAEDGEEPTLGHQVQRAVSMATLAALCEAVDQHPVLQLDAEPMDRFLSTLPLNQMLQKPRSEEQNGCVHPLENGSVFEESSSSQGWGKIAAQYLHDQWVCLSFLLRKHYPLIPTTESDRLECFLPAVEMPVQTLRSALDVLTVLPAGCILPVFRCMEVLVPKLLTSDESLCIESFDMAWKIISSLSNTQLTFWPNLKAFIHFVFNNEILTIAAKLKGQGYFKIKEIMCKIIEMSSIKTGVFNILICHCCQSWIAAACGVSHSSLFSSAKDYSELVLEACVFGTVFRRDQRLIQDVQTFIENLGQDCAANIIIENTKREDYYVRICAVKFLCLLDGSNISHKLFIEDLAIQLLDKDESTSRSRTRYHENSLQHRVKNRAWQTLLVLFPRFDQNFLNGIIDKIFHAGFTNNQASIKYFIEWIIILILHKFPQFLPKFWDCFSYGEEKLKTSICTFLSVLSHLDIIIQNIPEKRLVLKQALTIALQWCLSHNFSVRLYALVALKKAWQLCKALKFEECDAWTTVIECSLSQAESMHGAGNARKNWQRIQDHFFFSTFHPLKDYCLECLACKPWKGIFNSKQKSEQISKRK", "length": 1337, "header": "tr|A0A9J7FLG3-1|A0A9J7FLG3_CRIGR Computationally mapped isoform of Probable methyltransferase TARBP1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Tarbp1 PE=4 SV=1 CANONICAL=A0A9J7JJ17-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17/entry#A0A9J7GUH9-1", "sequence": { "sequence": "MERVLADALLAQSREPCALLGTLCGGEATAERAETLRLVLQRLEERGVGAGALAEAAHEVAKGHLVPLLKASPGGGPAGPRVLRAASAALRSCARLAGPELAVALAEDALRELPRVPAVELLAAVAPCLRALEDAPLLRRLARASVELALAGDAPPAVGARLLPALSLSAEPALREAWDTLASSGPEAEGRTGPELLVLSALAEKLLSADARHADLDARLRGSFWRTVQAGLGRAQDALTRKRARYLLQRAVQLSAELAMDCYCGPQDTLGPSLFWWSEKKKDELLKFWENYILIMEVLEGNQIHVIKPVLPKLNSLFEYAVSEENGCWLFHPSWHMCIYKRMFESENKILTKEGVIHFLELYEVKSLPYSPELSEFITGPLMDALSESCLYSRSPGQLLGSGSPLGLKLQKFLVTYVSLLPEETKSHFLLKFIQRMADRHWCAVPILFLSKALASLPRCKALGGEGLLALRDVLQCTMITHQVLLRGAAQCYLLQTAMHLVDVLCDWLRVNERYFRQSLIGGSDGQETSLNAYVKKLVQEFVKSPGWERESCFMPDWLEARLTSLMVLLAVDVEGMKTQFREKQRTQNVLRIFLDPLLDALGKLATNAYMPLLRTDRCLQLLARLLHSCVPRGSSGQDDEVSSVLQTSIMSVADSVSQFVLRRLTMNELQSVADLDRCQLYLKVLAELTSLQVKQGWKAGNPISRVISPLKNACIHHLQEAEDGEEPTLGHQVQRAVSMATLAALCEAVDQHPVLQLDAEPMDRFLSTLPLNQMLQKPRSEEQNGCVHPLENGSVFEESSSSQGWGKIAAQYLHDQWVCLSFLLRKHYPLIPTTESDRLECFLPAVEMPVQTLRSALDVLTVLPAGCILPVFRCMEVLVPKLLTSDESLCIESFDMAWKIISSLSNTQLTFWPNLKAFIHFVFNNEILTIAAKLKGQGYFKIKEIMCKIIEMSSIKTGVFNILICHCCQSWIAAACGVSHSSLFSSAKDYSELVLEACVFGTVFRRDQRLIQDVQTFIENLGQDCAANIIIENTKREDYYVRICAVKFLCLLDGSNISHKLFIEDLAIQLLDKDESTSRSRTRYHENSLQHRVKNRAWQTLLVLFPRFDQNFLNGIIDKIFHAGFTNNQASIKYFIEWIIILILHKFPQFLPKFWDCFSYGEEKLKTSICTFLSVLSHLDIIIQNIPEKRLVLKQALTIALQWCLSHNFSVRLYALVALKKAWQLCKALKFEECDAWTTVIECSLSQAESMHGAGNARKNWQRIQDHFFFSTFHPLKDYCLETIFYTLPRLSGITEEEWITLDKFASFTDIPSNTGSHWYLSGTALGELSPGDWSQQDRGYTLGEAESQSEWADVQKKIIPWGHKALESDLELMFQDRAAKLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGAAVLVVGSLQCVSDRQFQHLSVSAEQWLPLVEVRPAQLTDYLQQKKAEGYTVIGVEQTAQSSDLAQYRFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLGCAGLAS", "length": 1547, "header": "tr|A0A9J7GUH9-1|A0A9J7GUH9_CRIGR Computationally mapped isoform of tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1 OS=Cricetulus griseus OX=10029 GN=Tarbp1 PE=3 SV=1 CANONICAL=A0A9J7JJ17-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ17-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17/entry#A0A9J7JJ17-1", "sequence": { "sequence": "MERVLADALLAQSREPCALLGTLCGGEATAERAETLRLVLQRLEERGVGAGALAEAAHEVAKGHLVPLLKASPGGGPAGPRVLRAASAALRSCARLAGPELAVALAEDALRELPRVPAVELLAAVAPCLRALEDAPLLRRLARASVELALAGDAPPAVGARLLPALSLSAEPALREAWDTLASSGPEAEGRTGPELLVLSALAEKLLSADARHADLDARLRGSFWRTVQAGLGRAQDALTRKRARYLLQRAVQLSAELAMDCYCGPQDTLGPSLFWWSEKKKDELLKFWENYILIMEVLEGNQIHVIKPVLPKLNSLFEYAVSEENGCWLFHPSWHMCIYKRMFESENKILTKEGVIHFLELYEVKSLPYSPELSEFITGPLMDALSESCLYSRSPGQLLGSGSPLGLKLQKFLVTYVSLLPEETKSHFLLKFIQRMADRHWCAVPILFLSKALASLPRCKALGGEGLLALRDVLQCTMITHQVLLRGAAQCYLLQTAMHLVDVEKVSLSDISAFLVSLRQEESLGRGTMLWTELCDWLRVNERYFRQSLIGGSDGQETSLNAYVKKLVQEFVKSPGWERESCFMPDWLEARLTSLMVLLAVDVEGMKTQFREKQRTQNVLRIFLDPLLDALGKLATNAYMPLLRTDRCLQLLARLLHSCVPRGSSGQDDEVSSVLQTSIMSVADSVSQFVLRRLTMNELQSVADLDRCQLYLKVLAELTSLQVKQGWKAGNPISRVISPLKNACIHHLQEAEDGEEPTLGHQVQRAVSMATLAALCEAVDQHPVLQLDAEPMDRFLSTLPLNQMLQKPRSEEQNGCVHPLENGSVFEESSSSQGWGKIAAQYLHDQWVCLSFLLRKHYPLIPTTESDRLECFLPAVEMPVQTLRSALDVLTVLPAGCILPVFRCMEVLVPKLLTSDESLCIESFDMAWKIISSLSNTQLTFWPNLKAFIHFVFNNEILTIAAKLKGQGYFKIKEIMCKIIEMSSIKTGVFNILICHCCQSWIAAACGVSHSSLFSSAKDYSELVLEACVFGTVFRRDQRLIQDVQTFIENLGQDCAANIIIENTKREDYYVRICAVKFLCLLDGSNISHKLFIEDLAIQLLDKDESTSRSRTRYHENSLQHRVKNRAWQTLLVLFPRFDQNFLNGIIDKIFHAGFTNNQASIKYFIEWIIILILHKFPQFLPKFWDCFSYGEEKLKTSICTFLSVLSHLDIIIQNIPEKRLVLKQALTIALQWCLSHNFSVRLYALVALKKAWQLCKALKFEECDAWTTVIECSLSQAESMHGAGNARKNWQRIQDHFFFSTFHPLKDYCLETIFYTLPRLSGITEEEWITLDKFASFTDIPSNTGSHWYLSGTALGELSPGDWSQQDRGYTLGEAESQSEWADVQKKIIPWGHKALESDLELMFQDRAAKLGKSISRLIVVASLIDKPTNLGGLCRTCEVFGAAVLVVGSLQCVSDRQFQHLSVSAEQWLPLVEVRPAQLTDYLQQKKAEGYTVIGVEQTAQSSDLAQYRFPEKSLLLLGNEREGIPANLIQQLDVCVEIPQQGIIRSLNVHVSGALLIWEYTRQQLLGCAGLAS", "length": 1577, "header": "tr|A0A9J7JJ17-1|A0A9J7JJ17_CRIGR Isoform 1 of tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1 OS=Cricetulus griseus OX=10029 GN=Tarbp1 PE=3 SV=1 CANONICAL=A0A9J7JJ17-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FL78", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL78" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FL78", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL78" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770970", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770970", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17" } ], "pmid": "" }, { "name": "tRNA (guanine(18)-2'-O)-methyltransferase activity", "id": "GO:0141100", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0141100", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17" } ], "pmid": "" }, { "name": "tRNA (guanine) methyltransferase activity", "id": "GO:0016423", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016423", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA methylation", "id": "GO:0030488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030488", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ17", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1087, "end_pos": 1089, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1239, "end_pos": 1241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20077", "name": "", "equation": "guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7JJ17-1" ], "evidence": [ { "id": "20077", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20077" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7JJ17", "gene_name": "Tarbp1", "activity": [ { "ec_number": "2.1.1.34", "activity": "guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A9J7JJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17" } ] }, { "ec_number": "2.1.1.34", "activity": "", "evidence": [ { "id": "A0A9J7JJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17" }, { "id": "PF25050", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25050" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TARBP1", "eco_id": "ECO_0000259", "start_pos": 197, "end_pos": 323, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JJ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ17" }, { "id": "PF00588", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00588" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "tRNA/rRNA methyltransferase SpoU type", "eco_id": "ECO_0000259", "start_pos": 1420, "end_pos": 1561, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.34", "ec_name": "guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "2.1.1.34", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.34" }, { "id": "2.1.1.34", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.34" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1087, "end_pos": 1089 }, { "start_pos": 1239, "end_pos": 1241 }, { "start_pos": 823, "end_pos": 825 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A9J7JJ40", "uniprot_id": "A0A9J7JJ40_CRIGR", "mass": { "chemical_mass": 42158.0, "monoisotopic_mass": 42158.0 }, "refseq": { "ac": "XP_027262906", "name": "arsenite methyltransferase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262906" }, "gene_names": [ { "name": "As3mt", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40" } ] }, { "name": "As3mt", "type": "synonym", "evidence": [ { "id": "XP_027262906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262906" } ] } ], "protein_names": [ { "name": "Arsenite methyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.137", "type": "synonym", "evidence": [ { "id": "A0A9J7JJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40/entry#names_and_taxonomy" } ] }, { "name": "arsenite methyltransferase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027262906", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262906" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262906" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "As3mt", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40", "locus": {} } ], "crossref": [ { "id": "A0A9J7JJ40", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JJ40", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758973", "url": "https://www.ncbi.nlm.nih.gov/gene/100758973", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758973", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758973", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JJ40", "url": "https://www.orthodb.org/?gene=A0A9J7JJ40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43675:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43675:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13847", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13847", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262906", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262906", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "69432", "url": "https://www.rhea-db.org/rhea/69432", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69460", "url": "https://www.rhea-db.org/rhea/69460", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "69464", "url": "https://www.rhea-db.org/rhea/69464", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FLH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPRDAEIHKDVQNYYGNVLKTSANLQTNACVTAATLVPKYIRETLKNVHEDVTSRYYGCGLVVPERLENCQVLDLGCGSGRDCYMLSQLVGKKGHVTGIDMTKAQVEVAKTYLEYHMEKFGFQAPNVTFIQGCIEKLTEAGVQKESYDIVVSNCVINLVPDKQQVLQEVYGALKYGGELYFSDVYASLEVPEDIKSHKVLWGECLGGALYWKDLAIIAQKIGFSLPRLVTANIITVQNKELESVIGDCRFVSATFRLFKLPKTEPAKRCQVVYKGGITGHEKELIFDANFTFKEGEAVEVDEETAAVLKNSRFGQDFLFTPVGATLLAMRGRSELETKDIIRDPFKLAEESDKVKSKHAPDGTGGCCGKKQSCCGKKQS", "length": 381, "header": "tr|A0A9J7JJ40-1|A0A9J7JJ40_CRIGR Isoform 1 of Arsenite methyltransferase OS=Cricetulus griseus OX=10029 GN=As3mt PE=3 SV=1 CANONICAL=A0A9J7JJ40-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FLH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40/entry#A0A9J7FLH9-1", "sequence": { "sequence": "MAAPRDAEIHKDVQNYYGNVLKTSANLQTNACVTAATLVPKYIRETLKNVHEDVTSRYYGCGLVVPERLENCQVLDLGCGSGRDCYMLSQLVGKKGHVTGIDMTKAQVEVAKTYLEYHMEKFGFQAPNVTFIQGCIEKLTEAGVQKESYDIVVSNCVINLVPDKQQVLQEVYGALKYGGELYFSDVYASLEVPEDIKSHKVLWGECLGGALYWKDLAIIAQKIGFSLPRLVTANIITVQNKELESVIGDCRFVSATFRLFKLPKTEPAKRCQVVYKGGITGHEKELIFDANFTFKDIIRDPFKLAEESDKVKSKHAPDGTGGCCGKKQSCCGKKQS", "length": 336, "header": "tr|A0A9J7FLH9-1|A0A9J7JJ40_CRIGR Computationally mapped isoform of Arsenite methyltransferase OS=Cricetulus griseus OX=10029 GN=As3mt PE=3 SV=1 CANONICAL=A0A9J7JJ40-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40/entry#A0A9J7JJ40-1", "sequence": { "sequence": "MAAPRDAEIHKDVQNYYGNVLKTSANLQTNACVTAATLVPKYIRETLKNVHEDVTSRYYGCGLVVPERLENCQVLDLGCGSGRDCYMLSQLVGKKGHVTGIDMTKAQVEVAKTYLEYHMEKFGFQAPNVTFIQGCIEKLTEAGVQKESYDIVVSNCVINLVPDKQQVLQEVYGALKYGGELYFSDVYASLEVPEDIKSHKVLWGECLGGALYWKDLAIIAQKIGFSLPRLVTANIITVQNKELESVIGDCRFVSATFRLFKLPKTEPAKRCQVVYKGGITGHEKELIFDANFTFKEGEAVEVDEETAAVLKNSRFGQDFLFTPVGATLLAMRGRSELETKDIIRDPFKLAEESDKVKSKHAPDGTGGCCGKKQSCCGKKQS", "length": 381, "header": "tr|A0A9J7JJ40-1|A0A9J7JJ40_CRIGR Isoform 1 of Arsenite methyltransferase OS=Cricetulus griseus OX=10029 GN=As3mt PE=3 SV=1 CANONICAL=A0A9J7JJ40-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FLH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLH9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FLH9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLH9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758973", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758973", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "toxin metabolic process", "id": "GO:0009404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009404", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40" } ], "pmid": "" }, { "name": "arsonoacetate metabolic process", "id": "GO:0018872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40" } ], "pmid": "" }, { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "arsenite methyltransferase activity", "id": "GO:0030791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030791", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "69432", "name": "", "equation": "arsenic triglutathione + 3 [thioredoxin]-dithiol + 3 S-adenosyl-L-methionine = trimethylarsine + 3 [thioredoxin]-disulfide + 3 glutathione + 3 S-adenosyl-L-homocysteine + 3 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7JJ40-1" ], "evidence": [ { "id": "69432", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69432" } ] }, { "id": "69460", "name": "", "equation": "arsenic triglutathione + [thioredoxin]-dithiol + S-adenosyl-L-methionine + 2 H2O = methylarsonous acid + [thioredoxin]-disulfide + 3 glutathione + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7JJ40-1" ], "evidence": [ { "id": "69460", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69460" } ] }, { "id": "69464", "name": "", "equation": "arsenic triglutathione + 2 [thioredoxin]-dithiol + 2 S-adenosyl-L-methionine + H2O = dimethylarsinous acid + 2 [thioredoxin]-disulfide + 3 glutathione + 2 S-adenosyl-L-homocysteine + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7JJ40-1" ], "evidence": [ { "id": "69464", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/69464" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7JJ40", "gene_name": "As3mt", "activity": [ { "ec_number": "2.1.1.137", "activity": "arsenic triglutathione + 3 [thioredoxin]-dithiol + 3 S-adenosyl-L-methionine = trimethylarsine + 3 [thioredoxin]-disulfide + 3 glutathione + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A9J7JJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40" } ] }, { "ec_number": "2.1.1.137", "activity": "", "evidence": [ { "id": "A0A9J7JJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JJ40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ40" }, { "id": "PF13847", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13847" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 218, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.1.1.137", "ec_name": "arsenic triglutathione + 3 [thioredoxin]-dithiol + 3 S-adenosyl-L-methionine = trimethylarsine + 3 [thioredoxin]-disulfide + 3 glutathione + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "2.1.1.137", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.1.1.137" }, { "id": "2.1.1.137", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.137" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 291, "end_pos": 293 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JH25-1", "uniprot_ac": "A0A9J7JH25", "uniprot_id": "A0A9J7JH25_CRIGR", "mass": { "chemical_mass": 32952.0, "monoisotopic_mass": 32952.0 }, "refseq": { "ac": "XP_027262828", "name": "max-interacting protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262828" }, "gene_names": [ { "name": "Mxi1", "type": "recommended", "evidence": [ { "id": "A0A9J7JH25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25" } ] }, { "name": "Mxi1", "type": "synonym", "evidence": [ { "id": "XP_027262828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262828" } ] } ], "protein_names": [ { "name": "Max-interacting protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7JH25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25/entry#names_and_taxonomy" } ] }, { "name": "max-interacting protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027262828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262828" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262828" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mxi1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25", "locus": {} } ], "crossref": [ { "id": "A0A9J7JH25", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JH25", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18930", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18930", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758403", "url": "https://www.ncbi.nlm.nih.gov/gene/100758403", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758403", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758403", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JH25", "url": "https://www.orthodb.org/?gene=A0A9J7JH25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11969:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11969:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262828", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FLP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JD06", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JD06-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKRGRPRKEPRCEGSGLVPVAPPAMPPAAAAPQPPAQPEEPAGAKPRCPFSDIFNTSENSMEKHINTFLQNVQILLEAASYLEQIEKENKKCEHGYASSFPSMPSPRLQHSKPPRRLSRTQKHSSGSSTTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGDVDTISTTSISDIDDHSSLQSIGSDEGYSSASVKLPFTS", "length": 295, "header": "tr|A0A9J7JH25-1|A0A9J7JH25_CRIGR Isoform 1 of Max-interacting protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mxi1 PE=4 SV=1 CANONICAL=A0A9J7JH25-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FLP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25/entry#A0A9J7FLP8-1", "sequence": { "sequence": "MERVRMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRTQKHSSGSSTTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGDVDTISTTSISDIDDHSSLQSIGSDEGYSSASVKLPFTS", "length": 228, "header": "tr|A0A9J7FLP8-1|A0A9J7JH25_CRIGR Computationally mapped isoform of Max-interacting protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mxi1 PE=4 SV=1 CANONICAL=A0A9J7JH25-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JD06-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25/entry#A0A9J7JD06-1", "sequence": { "sequence": "MPSPRLQHSKPPRRLSRTQKHSSGSSTTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGDVDTISTTSISDIDDHSSLQSIGSDEGYSSASVKLPFTS", "length": 192, "header": "tr|A0A9J7JD06-1|A0A9J7JD06_CRIGR Computationally mapped isoform of Max-interacting protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Mxi1 PE=4 SV=1 CANONICAL=A0A9J7JH25-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JH25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25/entry#A0A9J7JH25-1", "sequence": { "sequence": "MGKRGRPRKEPRCEGSGLVPVAPPAMPPAAAAPQPPAQPEEPAGAKPRCPFSDIFNTSENSMEKHINTFLQNVQILLEAASYLEQIEKENKKCEHGYASSFPSMPSPRLQHSKPPRRLSRTQKHSSGSSTTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGDVDTISTTSISDIDDHSSLQSIGSDEGYSSASVKLPFTS", "length": 295, "header": "tr|A0A9J7JH25-1|A0A9J7JH25_CRIGR Isoform 1 of Max-interacting protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mxi1 PE=4 SV=1 CANONICAL=A0A9J7JH25-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FLP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLP8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FLP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLP8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758403", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758403", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JH25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH25" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 134, "end_pos": 186, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 135, "end_pos": 137 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JJ84-1", "uniprot_ac": "A0A9J7JJ84", "uniprot_id": "A0A9J7JJ84_CRIGR", "mass": { "chemical_mass": 46693.0, "monoisotopic_mass": 46693.0 }, "refseq": { "ac": "XP_007615396", "name": "palmitoyltransferase ZDHHC16 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007615396" }, "gene_names": [ { "name": "Zdhhc16", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ84" } ] }, { "name": "Zdhhc16", "type": "synonym", "evidence": [ { "id": "XP_007615396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007615396" } ] } ], "protein_names": [ { "name": "Palmitoyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ84/entry#names_and_taxonomy" } ] }, { "name": "2.3.1.225", "type": "synonym", "evidence": [ { "id": "A0A9J7JJ84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ84/entry#names_and_taxonomy" } ] }, { "name": "palmitoyltransferase ZDHHC16 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007615396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007615396" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613664.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007615396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007615396" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ84", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ84" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zdhhc16", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ84", "locus": {} } ], "crossref": [ { "id": "A0A9J7JJ84", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JJ84", "database": "AlphaFoldDB", "categories": [] }, { "id": "100757953", "url": "https://www.ncbi.nlm.nih.gov/gene/100757953", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757953", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757953", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FLR7", "url": "https://www.orthodb.org/?gene=A0A9J7FLR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JJ84", "url": "https://www.orthodb.org/?gene=A0A9J7JJ84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01529", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01529", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007615396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007615396", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "36683", "url": "https://www.rhea-db.org/rhea/36683", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FLR7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ84", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ84-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ84-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKSVLGFCRAEQLSSFASLQVIHSTTGAMRGQRNLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPIYWLVDNVIRWFGVVFVVLVIVLTGSIVAIAYLCVLPLILRTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDIATVSICKKCIYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIEKMKQLDKNKLQAIANQTYHQTPPPTFSFRERITHKSLVYLWFLCSSVALALGALTIWHAILISRGETSIERHINKKERRRLQAKGRVFRNPYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV", "length": 406, "header": "tr|A0A9J7JJ84-1|A0A9J7JJ84_CRIGR Isoform 1 of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc16 PE=3 SV=1 CANONICAL=A0A9J7JJ84-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FLR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ84/entry#A0A9J7FLR7-1", "sequence": { "sequence": "MGKSVLGFCRAEQLSSFASLQVIHSTTGAMRGQRNLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPIYWLVDNVIRWFGVVFVVLVIVLTGSIVAIAYLCVLPLILRTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDIATVSICKKCIYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIETYHQTPPPTFSFRERITHKSLVYLWFLCSSVALALGALTIWHAILISRGETSIERHINKKERRRLQAKGRVFRNPYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV", "length": 390, "header": "tr|A0A9J7FLR7-1|A0A9J7JJ84_CRIGR Computationally mapped isoform of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc16 PE=3 SV=1 CANONICAL=A0A9J7JJ84-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ84-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ84/entry#A0A9J7JJ84-1", "sequence": { "sequence": "MGKSVLGFCRAEQLSSFASLQVIHSTTGAMRGQRNLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPIYWLVDNVIRWFGVVFVVLVIVLTGSIVAIAYLCVLPLILRTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDIATVSICKKCIYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIEKMKQLDKNKLQAIANQTYHQTPPPTFSFRERITHKSLVYLWFLCSSVALALGALTIWHAILISRGETSIERHINKKERRRLQAKGRVFRNPYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV", "length": 406, "header": "tr|A0A9J7JJ84-1|A0A9J7JJ84_CRIGR Isoform 1 of Palmitoyltransferase OS=Cricetulus griseus OX=10029 GN=Zdhhc16 PE=3 SV=1 CANONICAL=A0A9J7JJ84-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FLR7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLR7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757953", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757953", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ84", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-cysteine S-palmitoyltransferase activity", "id": "GO:0019706", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#names_and_taxonomy" } ] }, { "name": "3.6.1.1", "type": "synonym", "evidence": [ { "id": "A0A9J7JK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#names_and_taxonomy" } ] }, { "name": "BNIP2 motif-containing molecule at the C-terminal region 1", "type": "synonym", "evidence": [ { "id": "A0A9J7JK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#names_and_taxonomy" } ] }, { "name": "Pyrophosphate phospho-hydrolase", "type": "synonym", "evidence": [ { "id": "A0A9J7JK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#names_and_taxonomy" } ] }, { "name": "protein prune homolog 2 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_027262370", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262370" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262370", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262370" } ] }, { "annotation": "May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK96", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96#function" }, { "database": "UniProtKB", "id": "ARBA00056879", "url": "https://www.uniprot.org/uniprotkb/ARBA00056879#function" }, { "database": "UniProtKB", "id": "A0A9J7K382", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K382#function" }, { "database": "UniProtKB", "id": "A0A9J7K6K9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6K9#function" }, { "database": "UniProtKB", "id": "A0A9J7GT48", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT48#function" }, { "database": "UniProtKB", "id": "A0A9J7GX67", "url": 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"taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK96", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100767704", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96", "locus": {} } ], "crossref": [ { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767704", "url": "https://www.ncbi.nlm.nih.gov/gene/100767704", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022181", "url": 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[ "Protein Classification" ] }, { "id": "PTHR12112:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12112:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12112:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12112:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13716", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13716", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262370", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262370", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24576", "url": "https://www.rhea-db.org/rhea/24576", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7FNM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FNM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FNR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FNR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GRK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GRK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GSB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GSB7", 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}, { "id": "A0A9J7GU69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GU69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GU69-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GU69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVC2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWW7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWW7-1", "url": 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"MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRYDEEKSFKRSVRLDEELREASETAKTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 3083, "header": "tr|A0A9J7JK96-1|A0A9J7JK96_CRIGR Isoform 1 of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FNM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7FNM9-1", "sequence": { "sequence": "MTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRYDEEKSFKRSVRLDEELREASETAKTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 2907, "header": "tr|A0A9J7FNM9-1|A0A9J7JK96_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FNR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7FNR3-1", "sequence": { "sequence": "MNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRYDEEKSFKRSVRLDEELREASETAKTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 3025, "header": "tr|A0A9J7FNR3-1|A0A9J7FNR3_CRIGR Computationally mapped isoform of Protein prune homolog 2 isoform X17 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GRK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7GRK4-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRLDEELREASETAKTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 3071, "header": "tr|A0A9J7GRK4-1|A0A9J7GRK4_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GSB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7GSB7-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRYDEEKSFKRSVRLDEELREASETAKTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 3080, "header": "tr|A0A9J7GSB7-1|A0A9J7GSB7_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GT22-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7GT22-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRYDEEKSFKRSVRLDEELREASETAKTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 3082, "header": "tr|A0A9J7GT22-1|A0A9J7GT22_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GT48-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7GT48-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 3058, "header": "tr|A0A9J7GT48-1|A0A9J7GT48_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GU18-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7GU18-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRYDEEKSFKRSVSIDLKLKEKP", "length": 3054, "header": "tr|A0A9J7GU18-1|A0A9J7GU18_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GU69-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7GU69-1", "sequence": { "sequence": "MVLLRRSNGKGTEPRRIFFFLSCPKGESSIPLPNGYDIHGNYVACCASEEARGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRYDEEKSFKRSVRLDEELREASETAKTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 2966, "header": "tr|A0A9J7GU69-1|A0A9J7GU69_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7GVC2-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRLDEELREASETAKTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 3067, "header": "tr|A0A9J7GVC2-1|A0A9J7GVC2_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7GVQ0-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRYDEEKSFKRSVRLDEELREASETANIDLKLKEKP", "length": 3067, "header": "tr|A0A9J7GVQ0-1|A0A9J7GVQ0_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7GWW7-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRYDEEKSFKRSVRTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 3070, "header": "tr|A0A9J7GWW7-1|A0A9J7GWW7_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GX67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7GX67-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRLDEELREASETANIDLKLKEKP", "length": 3055, "header": "tr|A0A9J7GX67-1|A0A9J7GX67_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JK96-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7JK96-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVRYDEEKSFKRSVRLDEELREASETAKTSCLYNDPEMTSMEKDIDLKLKEKP", "length": 3083, "header": "tr|A0A9J7JK96-1|A0A9J7JK96_CRIGR Isoform 1 of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JW65-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7JW65-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGAQNSAVKLSMSVVYLNSVG", "length": 2908, "header": "tr|A0A9J7JW65-1|A0A9J7JW65_CRIGR Computationally mapped isoform of inorganic diphosphatase OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K382-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7K382-1", "sequence": { "sequence": "MEEFLQRAKSKLDRSKRLEKVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVMNIPRTEFSYFTETRFILEELNISESSHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRSLEAAVVRVINPDEQSDGELGLPESSSSLVLKELLREAPELITQQLAHLLRGSILFKWMTMDPELPEKQEDILSILEEQFPNLPPRDDIISVLQETQLSAQGLSIEQTILKDLKELSDGEIKVAVSTVNMTLEDCLFHSNITSDLKAFTDKFGFDVLILIASYTAEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTCDQVVLLVKEVINRRCTEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQVDVNVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHSLLPGFDSYSPIPEGVVAEEHARSGEHSEHFDLFNFDPAPMASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGIGMSNYSSSSLLSETGKDSLVEFDEEFIQRQESSGDSSERNLSLTCFVGDELSSPQRLKNTAKRIPPTPMNSFIEISPSNEEPVPLYPEDIVQNAVDTGHLGPPQIRARCSSWWGGLEIDSKNIVDAWNSSEQEPVFQSPESWKDHKPGPLERRTSDSAFQPKSLGFPKSDPWESEFDQPELGSKDTQDQKKESLQCQYPPTERPHLTDASPQGTNHLIEDFAALWHSGHSPTMMPEPWGKPSDAVDAAVTVPFRAWGAFNKKDSAETLNSAWNLHPTNPEPPSVQDPNEWAMAKSGFSFPNGDLLDNSLIQINEDEAPEIWSKKNNGSKDNILTSGSPISDLGQTWNNSKLPGEDQNGLVDSKARGKVYEKEGSWNLFEESVRKRGSDGLAPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEMENKPFAKETGFEAKDTGGPAEGVEALAMSPQQPQRNRVGSGPGNLDMWASPHEDDKPEGSDTYHPDQDLLETGHAKDENASMEDDVGESSPSSYDDPSMMQLYNEANRQLTLLHSNTNSRQAAPDSLDTWNRVILEDTQSTATISDMDNDLDWDDCSGGVAISDGQAEGYIAANTEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGNTGPSEYHALNEKSGQLIANSIWDSVMRDKDMPSFSLPSPPNTTDMEQSTPESPGHSVNGKDSHMLEASGLSESAVLTSQPDNQHTWTESQGGTASLVTKLESLEQVSQSDPWTGHTYRQSENEIEGLAGSVNGHLIKDSAIASGLDGTLWASGKEPSDQELSFSAAFEHPEICSASGKINPLSVTPSPQTEAPKEALEVGKESYALDAFAAQTEVPTSNFQTKQTNEESLMDHGNSDETIATVNGINLIKNMPLSEMELEKTEDHNLLEPERANERLLYESPQNFHAWDGPIDSDVWDSHISYEAATDPAGQGTENKVPEALSPGNYDRDSLSSGCTHSSMSSPDLNNSSVALSWTHGPSTELQEEDQDDRSKQTHQEPELFPTESQVEVITEMRDFAKNRKDGFGKMFDHKDPKFPEIPSDSINGDSSSSSSSLGTDKYSEYSHAYQEGNVMISCQEENELVEIVQPEDTRIEDTSSGSDDDSGGDEELMEKRPHLATCEVSQSEPGAYDSLHEPTFLTTEDAQSKFSVFVGSSEPMEKESKPNPFCDSQQSSPGQWILSPLMQTDTQDTSMETKAAETGKMGDNIWPVTPRTEPQDGDPAQLEMLGFSTDSSEWWNTPLQEGKPNASVSAEVLSISEGELEATSPEATSPVFQNSGPWGTPTQSDSEPVDTGNTSPFSGKLKSPFLDSNGDKSYEKLWNIQPKQLDSEADQFSQLVILNQIKDKDSGQQTAMPSAAGDLFAEACTQEQCQESMLSDWDHPDPVFTNRYENGYVSPGLSPTECQQENWWKQEKSYLSQVTYSSPVTENLPEVNAPTQLINKSGSEWDSPSPSERKHNFVPDILHGNFQEGGPLASASPDLWVDVKQPFTFKDDTENPDILTHCDHDSNSQASSSPDVCHDSEGTQEMEKHTGVYLGPEVEPSELDLTEPKMNDDELTQGPGMESLPQAIPLPPINIQKDINGSSMPASPESSPEPSDMHRDNNTSLTALEKDTDPQVEAEAGMIAGAGSVDTDTPVTHQEVSIEGNGSWVSEDLFPESQTGTGALLDCEQPFASENPAVLTDILLASDTCLDVSEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEDLMKEPEHFRYGGDLQLEEGTLKQSLTPYTPPFDLSYLTEPAAAAETAQEAGSPDDTSLGSDAAEMLLSALPDQREENHTETSSRQPRHQTMTVLHIHGDPEALSSPVGGTGSNLDSSPSNIDWEIETDNPDSPAGGDMRLPNGVSKEMLELEEEKVIPTNGPEQTKLEYDEDKWTEKSEDHHALAVDYILVSHEKDSLLKPEAWEARENLPELEQFSTGSQETELPDTQLAGLPDTCQPESLNEVKANEVKERMSSDHNRRTSPENPEQEQSWMVLGHNEDGDPSSETRDTGLGSPDKTVEQFLSLSLDKGPQSQILGGNKPLDSLALEEVTDLNSQSRKSKRRGQAGLDAVPTQAATHDNEWEMLSPQLSQKNRIPPQEMEEETEFLESRPRKPRPNGFPSSEDVGMDVPFEEGVLSPSAADMRPEPPNSLDLNGSHPQRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHEDPMANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGDSGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIVSIDLKLKEKP", "length": 3042, "header": "tr|A0A9J7K382-1|A0A9J7K382_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K6K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96/entry#A0A9J7K6K9-1", "sequence": { "sequence": 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"length": 3068, "header": "tr|A0A9J7K6K9-1|A0A9J7K6K9_CRIGR Computationally mapped isoform of Protein prune homolog 2 OS=Cricetulus griseus OX=10029 GN=LOC100767704 PE=3 SV=1 CANONICAL=A0A9J7JK96-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1379, "start_aa": "Thr", "end_pos": 1379, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1379", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 608, "start_aa": "Thr", "end_pos": 608, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr608", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FNM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNM9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FNM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNM9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767704", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767704", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "pyrophosphatase activity", "id": "GO:0016462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016462", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK96", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK96", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96" } ], "pmid": "" }, { "name": "inorganic diphosphate phosphatase activity", "id": "GO:0004427", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004427", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK96", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK96", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK96", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": 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"annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2773, "end_pos": 2775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2788, "end_pos": 2790, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2837, "end_pos": 2839, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 528, "end_pos": 530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 669, "end_pos": 671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" }, { "start_pos": 867, "end_pos": 869, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" }, { "start_pos": 963, "end_pos": 965, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24576", "name": "", "equation": "diphosphate + H2O = 2 phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3HIL5-1", "G3H2Y2-1", "A0A9J7JK96-1", "A0A8C2MTG4-1" ], "evidence": [ { "id": "24576", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24576" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2MTG4", "gene_name": "Lhpp", "activity": [ { "ec_number": "3.6.1.1", "activity": "diphosphate + H2O = 2 phosphate + H(+).", "evidence": [ { "id": "A0A8C2MTG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTG4" } ] }, { "ec_number": "3.6.1.1", "activity": "", "evidence": [ { "id": "A0A8C2MTG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTG4" } ] } ] }, { "uniprot_ac": "A0A9J7JK96", "gene_name": "LOC100767704", "activity": [ { "ec_number": "3.6.1.1", "activity": "diphosphate + H2O = 2 phosphate + H(+).", "evidence": [ { "id": "A0A9J7JK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96" } ] }, { "ec_number": "3.6.1.1", "activity": "", "evidence": [ { "id": "A0A9J7JK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96" } ] } ] }, { "uniprot_ac": "G3H2Y2", "gene_name": "Prune1", "activity": [ { "ec_number": "3.6.1.1", "activity": "diphosphate + H2O = 2 phosphate + H(+).", "evidence": [ { "id": "G3H2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H2Y2" } ] }, { "ec_number": "3.6.1.1", "activity": "", "evidence": [ { "id": "G3H2Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H2Y2" } ] } ] }, { "uniprot_ac": "G3HIL5", "gene_name": "Alpl", "activity": [ { "ec_number": "3.1.3.1", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "G3HIL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HIL5" } ] }, { "ec_number": "3.1.3.1", "activity": "", "evidence": [ { "id": "G3HIL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HIL5" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JK96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK96" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 2875, "end_pos": 3039, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.6.1.1", "ec_name": "diphosphate + H2O = 2 phosphate + H(+).", 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"exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JKH0-1", "uniprot_ac": "A0A9J7JKH0", "uniprot_id": "A0A9J7JKH0_CRIGR", "mass": { "chemical_mass": 58976.0, "monoisotopic_mass": 58976.0 }, "refseq": { "ac": "XP_027262660", "name": "rab11 family-interacting protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262660" }, "gene_names": [ { "name": "Rab11fip2", "type": "recommended", "evidence": [ { "id": "A0A9J7JKH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" } ] }, { "name": "Rab11fip2", "type": "synonym", "evidence": [ { "id": "XP_027262660", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262660" } ] } ], "protein_names": [ { "name": "Rab11 family-interacting protein 2", "type": "recommended", "evidence": [ { "id": "A0A9J7JKH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0/entry#names_and_taxonomy" } ] }, { "name": "rab11 family-interacting protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027262660", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262660" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262660" } ] }, { "annotation": "A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FP47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FP47#function" }, { "database": "UniProtKB", "id": "ARBA00055128", "url": "https://www.uniprot.org/uniprotkb/ARBA00055128#function" }, { "database": "UniProtKB", "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0#function" }, { "database": "UniProtKB", "id": "A0A8C2M186", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M186#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rab11fip2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0", "locus": {} } ], "crossref": [ { "id": "A0A9J7JKH0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JKH0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08682", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08682", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773115", "url": "https://www.ncbi.nlm.nih.gov/gene/100773115", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037789", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037789", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773115", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773115", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JKH0", "url": "https://www.orthodb.org/?gene=A0A9J7JKH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15746:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15746:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262660", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M186", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M186", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M186-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M186-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FM30", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FM30-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FM30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FP47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FP47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FP47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FP47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKNDGTMSDTSSAVIPSTHTPDAKAVLSSSETQMKSKPKTPFLLGPQRLSSAHSMSDLTGSHLSSEKLKSSAIGPTYLLSRQIDSFGVVPESGSLKSPHRRTLSFDTSKLNPPGSIVDEGERSFGRQSDPFMNVTASLPQKSATLPRKRNPFEESSESWDNSMHLFSKPIEVRKENKREKKEKVSLFERVTGKKDSRRSEKLNNGGSDSPCDLKSPSAFNENRQDYFDYESTNPFTAKFRASTIMPSSSFHMNPTSSEDLRKIPQVCISFQDNNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGKFTNS", "length": 519, "header": "tr|A0A9J7JKH0-1|A0A9J7JKH0_CRIGR Isoform 1 of Rab11 family-interacting protein 2 OS=Cricetulus griseus OX=10029 GN=Rab11fip2 PE=4 SV=1 CANONICAL=A0A9J7JKH0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M186-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0/entry#A0A8C2M186-1", "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKNDGTMSDTSSAVIPSTHTPDAKAVLSSSETQMKSKPKTPFLLGPQRLSSAHSMSDLTGSHLSSEKLKSSAIGPTYLLSRQIDSFGVVPESGSLKSPHRRTLSFDTSKLNPPGSIVDEGERSFGRQSDPFMNVTASLPQKSATLPRKRNPFEESSESWDNSMHLFSKPIEVRKENKREKKEKVSLFERVTGKKDSRRSEKLNNGGSDSPCDLKSPSAFNENRQDYFDYESTNPFTAKFRASTIMPSSSFHMNPTSSEDLRKIPDNNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGKFTNS", "length": 512, "header": "tr|A0A8C2M186-1|A0A8C2M186_CRIGR Computationally mapped isoform of Rab11 family-interacting protein 2 OS=Cricetulus griseus OX=10029 GN=Rab11fip2 PE=4 SV=1 CANONICAL=A0A9J7JKH0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FM30-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0/entry#A0A9J7FM30-1", "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKNDGTMSDTSSAVIPSTHTPDAKAVLSSSETQMKSKPKTPFLLGPQRLSSAHSMSDLTGSHLSSEKLKSSAIGPTYLLSRQIDSFGVVPESGSLKSPHRRTLSFDTSKLNPPGSIVDEGERSFGRQSDPFMNVTASLPQKSATLPRKRNPFEESSESWDNSMHLFSKPIEVRKENKREKKEKVSLFERVTGKKDSRRSEKLNNGGSDSPCDLKSPSAFNENRQDYFDYESTNPFTAKFRASTIMPSSRTTILLMPRLGTGV", "length": 435, "header": "tr|A0A9J7FM30-1|A0A9J7FM30_CRIGR Computationally mapped isoform of Rab11 family-interacting protein 2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Rab11fip2 PE=4 SV=1 CANONICAL=A0A9J7JKH0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FP47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0/entry#A0A9J7FP47-1", "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKNDGTMSDTSSAVIPSTHTPDAKAVLSSSETQMKSKPKTPFLLGPQRLSSAHSMSDLTGSHLSSEKLKSSAIGPTYLLSRQIDSFGVVPESGSLKSPHRRTLSFDTSKLNPPGSIVDEGERSFGRQSDPFMNVTASLPQKSATLPRKRNPFEESSESWDNSMHLFSKPIEVRKENKREKKEKVSLFERVTGKKDSRRSEKLNNGGSDSPCDLKSPSAFNENRQDYFDYESTNPFTAKFRASTIMPSSSFHMNPTSSEDLRKIPVCISFQDNNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGKFTNS", "length": 518, "header": "tr|A0A9J7FP47-1|A0A9J7JKH0_CRIGR Computationally mapped isoform of Rab11 family-interacting protein 2 OS=Cricetulus griseus OX=10029 GN=Rab11fip2 PE=4 SV=1 CANONICAL=A0A9J7JKH0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0/entry#A0A9J7JKH0-1", "sequence": { "sequence": "MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVWKEEASFELPGLLMQGNPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWFRLESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKNDGTMSDTSSAVIPSTHTPDAKAVLSSSETQMKSKPKTPFLLGPQRLSSAHSMSDLTGSHLSSEKLKSSAIGPTYLLSRQIDSFGVVPESGSLKSPHRRTLSFDTSKLNPPGSIVDEGERSFGRQSDPFMNVTASLPQKSATLPRKRNPFEESSESWDNSMHLFSKPIEVRKENKREKKEKVSLFERVTGKKDSRRSEKLNNGGSDSPCDLKSPSAFNENRQDYFDYESTNPFTAKFRASTIMPSSSFHMNPTSSEDLRKIPQVCISFQDNNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDYIDNLLVRVMEETPSILRVPYEPSRKAGKFTNS", "length": 519, "header": "tr|A0A9J7JKH0-1|A0A9J7JKH0_CRIGR Isoform 1 of Rab11 family-interacting protein 2 OS=Cricetulus griseus OX=10029 GN=Rab11fip2 PE=4 SV=1 CANONICAL=A0A9J7JKH0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FP47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FP47" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FP47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FP47" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773115", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773115", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "phagocytic cup", "id": "GO:0001891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001891", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" } ], "pmid": "" }, { "name": "recycling endosome membrane", "id": "GO:0055038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" } ], "pmid": "" }, { "name": "recycling endosome", "id": "GO:0055037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" } ], "pmid": "" }, { "name": "regulated exocytosis", "id": "GO:0045055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045055", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" } ], "pmid": "" }, { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" } ], "pmid": "" }, { "name": "signaling", "id": "GO:0023052", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0023052", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JKH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 120, "start_aa": "Met", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JKH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH0" }, { "id": "PS51511", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51511" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FIP-RBD", "eco_id": "ECO_0000259", "start_pos": 444, "end_pos": 506, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 34, "end_pos": 36 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JIU6-1", "uniprot_ac": "A0A9J7JIU6", "uniprot_id": "A0A9J7JIU6_CRIGR", "mass": { "chemical_mass": 52766.0, "monoisotopic_mass": 52766.0 }, "refseq": { "ac": "XP_027265441", "name": "intracellular hyaluronan-binding protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265441" }, "gene_names": [ { "name": "Habp4", "type": "recommended", "evidence": [ { "id": "A0A9J7JIU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ] }, { "name": "Habp4", "type": "synonym", "evidence": [ { "id": "XP_027265441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265441" } ] } ], "protein_names": [ { "name": "Intracellular hyaluronan-binding protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7JIU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6/entry#names_and_taxonomy" } ] }, { "name": "intracellular hyaluronan-binding protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027265441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265441" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265441" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Habp4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6", "locus": {} } ], "crossref": [ { "id": "A0A9J7JIU6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JIU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100760637", "url": "https://www.ncbi.nlm.nih.gov/gene/100760637", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032381", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032381", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760637", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760637", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JIU6", "url": "https://www.orthodb.org/?gene=A0A9J7JIU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12299", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12299", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12299:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12299:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265441", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2N677", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N677", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2N677-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N677-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FQA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FQA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JEJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JEJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAAAAAAAASGAGHRGGRSPAVVSGHRPGAAGRRESQKERKSLAVWSAQQPDSPGGPQPPGQKRTPRRGEQQGWNDSRGTDVLDRAERRSYREYRPYDTERQADLTAEKFSDEKPVDRFDRDRPLRGRGGPRGLRSRGRGGPGNRAFDSFDQRGKRDFERYSSNDKVTNRMEDSMGSCGVRPWGSGKDASDTEPSASMEESSMMEESQGALDEESPAKLGIMFIEDKVVQHKRTRVHAWRPEHDTRKSHLLDNSSFSLLPTGIHSQASHKPGAPELEVEEENQVHEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDLVKDDYEDETHVFRKAANDITSQLEINFGSLPRPGRGARGSARGGRGRIRRTENYGPRAEVVVSGIIQDVAPNPNDPEDFPALA", "length": 474, "header": "tr|A0A9J7JIU6-1|A0A9J7JIU6_CRIGR Isoform 1 of Intracellular hyaluronan-binding protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Habp4 PE=3 SV=1 CANONICAL=A0A9J7JIU6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N677-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6/entry#A0A8C2N677-1", "sequence": { "sequence": "MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAAAAAAAASGAGHRGGRSPAVVSGHRPGAAGRRESQKERKSLAVWSAQQPDSPGGPQPPGQKRTPRRGEQQGWNDSRGTDVLDRAERRSYREYRPYDTERQADLTAEKFSDEKPVDRFDRDRPLRGRGGPRGLRSRGRGGPGNRAFDSFDQRGKRDFERYSSNDKVTNRMEDSMGSCGVRPWGSGKDASDTEPSASMEESSMMEESQGALDEESPAKAPELEVEEENQVHEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDLVKDDYEDETHVFRKAANDITSQLEINFGSLPRPGRGARGSARGGRGRIRRTENYGPRAEVVIQDVAPNPNDPEDFPALA", "length": 416, "header": "tr|A0A8C2N677-1|A0A8C2N677_CRIGR Computationally mapped isoform of Intracellular hyaluronan-binding protein 4 isoform X7 OS=Cricetulus griseus OX=10029 GN=Habp4 PE=3 SV=1 CANONICAL=A0A9J7JIU6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FQA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6/entry#A0A9J7FQA6-1", "sequence": { "sequence": "MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAAAAAAAASGAGHRGGRSPAVVSGHRPGAAGRRESQKERKSLAVWSAQQPDSPGGPQPPGQKRTPRRGEQQGWNDSRGTDVLDRAERRSYREYRPYDTERQADLTAEKFSDEKPVDRFDRDRPLRGRGGPRGLRSRGRGGPGNRAFDSFDQRGKRDFERYSSNDKVTNRMEDSMGSCGVRPWGSGKDASDTEPSASMEESSMMEESQGALDEESPAKLGIMFIEDKVVQHKRTRVHAWRPEHDTRKSHLLDNSSFSLLPTGIHSQASHKPGAPELEVEEENQVHEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDLVKDDYEDETHVFRKAANDITSQLEINFGSLPRPGRGARGSARGGRGRIRRTENYGPRAEVVIQDVAPNPNDPEDFPALA", "length": 470, "header": "tr|A0A9J7FQA6-1|A0A9J7JIU6_CRIGR Computationally mapped isoform of Intracellular hyaluronan-binding protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Habp4 PE=3 SV=1 CANONICAL=A0A9J7JIU6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JEJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6/entry#A0A9J7JEJ5-1", "sequence": { "sequence": "MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAAAAAAAASGAGHRGGRSPAVVSGHRPGAAGRRESQKERKSLAVWSAQQPDSPGGPQPPGQKRTPRRGEQQGWNDSRGTDVLDRAERRSYREYRPYDTERQADLTAEKFSDEKPVDRFDRDRPLRGRGGPRGLRSRGRGGPGNRAFDSFDQRGKRDFERYSSNDKVTNRMEDSMGSCGVRPWGSGKDASDTEPSASMEESSMMEESQGALDEESPAKLGIMFIEDKVVQHKRTRVHAWRPEHDTRAPELEVEEENQVHEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDLVKDDYEDETHVFRKAANDITSQLEINFGSLPRPGRGARGSARGGRGRIRRTENYGPRAEVVVSGIIQDVAPNPNDPEDFPALA", "length": 448, "header": "tr|A0A9J7JEJ5-1|A0A9J7JEJ5_CRIGR Computationally mapped isoform of Intracellular hyaluronan-binding protein 4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Habp4 PE=3 SV=1 CANONICAL=A0A9J7JIU6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6/entry#A0A9J7JIU6-1", "sequence": { "sequence": "MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAAAAAAAASGAGHRGGRSPAVVSGHRPGAAGRRESQKERKSLAVWSAQQPDSPGGPQPPGQKRTPRRGEQQGWNDSRGTDVLDRAERRSYREYRPYDTERQADLTAEKFSDEKPVDRFDRDRPLRGRGGPRGLRSRGRGGPGNRAFDSFDQRGKRDFERYSSNDKVTNRMEDSMGSCGVRPWGSGKDASDTEPSASMEESSMMEESQGALDEESPAKLGIMFIEDKVVQHKRTRVHAWRPEHDTRKSHLLDNSSFSLLPTGIHSQASHKPGAPELEVEEENQVHEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDLVKDDYEDETHVFRKAANDITSQLEINFGSLPRPGRGARGSARGGRGRIRRTENYGPRAEVVVSGIIQDVAPNPNDPEDFPALA", "length": 474, "header": "tr|A0A9J7JIU6-1|A0A9J7JIU6_CRIGR Isoform 1 of Intracellular hyaluronan-binding protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Habp4 PE=3 SV=1 CANONICAL=A0A9J7JIU6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6/entry#A0A9J7JKT5-1", "sequence": { "sequence": "MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAAAAAAAASGAGHRGGRSPAVVSGHRPGAAGRRESQKERKSLAVWSAQQPDSPGGPQPPGQKRTPRRGEQQGWNDSRGTDVLDRAERRSYREYRPYDTERQADLTAEKFSDEKPVDRFDRDRPLRGRGGPRGLRSRGRGGPGNRAFDSFDQRGKRDFERYSSNDKVTNRMEDSMGSCGVRPWGSGKDASDTEPSASMEESSMMEESQGALDEESPAKAPELEVEEENQVHEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDLVKDDYEDETHVFRKAANDITSQLEINFGSLPRPGRGARGSARGGRGRIRRTENYGPRAEVVVSGIIQDVAPNPNDPEDFPALA", "length": 420, "header": "tr|A0A9J7JKT5-1|A0A9J7JKT5_CRIGR Computationally mapped isoform of Intracellular hyaluronan-binding protein 4 isoform X6 OS=Cricetulus griseus OX=10029 GN=Habp4 PE=3 SV=1 CANONICAL=A0A9J7JIU6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6/entry#A0A9J7JLI0-1", "sequence": { "sequence": "MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILREAEHRRQQQLQRKRRDEAAAAAAAAAASGAGHRGGRSPAVVSGHRPGAAGRRESQKERKSLAVWSAQQPDSPGGPQPPGQKRTPRRGEQQGWNDSRGTDVLDRAERRSYREYRPYDTERQADLTAEKFSDENTNRMEDSMGSCGVRPWGSGKDASDTEPSASMEESSMMEESQGALDEESPAKLGIMFIEDKVVQHKRTRVHAWRPEHDTRKSHLLDNSSFSLLPTGIHSQASHKPGAPELEVEEENQVHEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDLVKDDYEDETHVFRKAANDITSQLEINFGSLPRPGRGARGSARGGRGRIRRTENYGPRAEVVVSGIIQDVAPNPNDPEDFPALA", "length": 421, "header": "tr|A0A9J7JLI0-1|A0A9J7JLI0_CRIGR Computationally mapped isoform of Intracellular hyaluronan-binding protein 4 isoform X5 OS=Cricetulus griseus OX=10029 GN=Habp4 PE=3 SV=1 CANONICAL=A0A9J7JIU6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQA6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQA6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760637", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760637", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of RNA splicing", "id": "GO:0033120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033120", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" }, { "name": "positive regulation of translational initiation", "id": "GO:0045948", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045948", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" }, { "name": "PML body organization", "id": "GO:0030578", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030578", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" }, { "name": "SUMO binding", "id": "GO:0032183", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032183", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 7, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" }, { "name": "Cajal body", "id": "GO:0015030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" }, { "name": "Gemini of Cajal bodies", "id": "GO:0097504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097504", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIU6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JIU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIU6" }, { "id": "SM01233", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Hyaluronan/mRNA-binding protein", "eco_id": "ECO_0000259", "start_pos": 215, "end_pos": 374, "start_aa": "Gly", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 314, "end_pos": 316 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JIV1-1", "uniprot_ac": "A0A9J7JIV1", "uniprot_id": "A0A9J7JIV1_CRIGR", "mass": { "chemical_mass": 159261.0, "monoisotopic_mass": 159261.0 }, "refseq": { "ac": "XP_027265457", "name": "protein patched homolog 1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265457" }, "gene_names": [ { "name": "Ptch1", "type": "recommended", "evidence": [ { "id": "A0A9J7JIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" } ] }, { "name": "Ptch1", "type": "synonym", "evidence": [ { "id": "XP_027265457", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265457" } ] } ], "protein_names": [ { "name": "Protein patched homolog 1 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7JIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1/entry#names_and_taxonomy" } ] }, { "name": "protein patched homolog 1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027265457", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265457" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265457", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265457" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptch1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1", "locus": {} } ], "crossref": [ { "id": "100763926", "url": "https://www.ncbi.nlm.nih.gov/gene/100763926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763926", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JIV1", "url": "https://www.orthodb.org/?gene=A0A9J7JIV1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46022", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46022", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46022:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46022:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12349", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12349", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27572", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27572", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265457", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265457", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FQB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FQB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASAGNAAGALGRQAGGGRRRRTGGPHRAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLHKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDVALVLNGGCQGLSRKYMHWQEELIVGGTVKNATGKLVSARALQTMFQLMTPKQMYEHFRGYEYVSHINWNEDRAAAILEAWQRTYVEVVHQSVAPNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTEPHSNTRYSPPPPYSSHSFAHETHITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVILLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHKSFSNVKYVMLEENKQLPQMWLHYFRDWLQGLQDAFDSDWETGRIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRVICNNYTSLGLSSYPNGYPFLFWEQYISLRHWLLLAISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNHRAMLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTVLGVLNGLVLLPVLLSFFGPCPEVSPANGLNRLPTPSPEPPPSVVRFAVPPGHMNNGSDSSDSEYSSQTTVSGISEELRHYEAQQGSGGPGHQVIVEATENPVFARSTVVHPESRHHPPLNPRQQPHLDSGSLSPGRQGQQPRRDPPREGLRPPPYRPRRDAFEISTEGHSGPSNRDRSGPRGARSYNPRNPTSTAMGSSVPSYGQPITTVTASASVTVAVHPPPGPGRNPRGGPCPGYESYPETDHGVFQDPHVPFHVRCERRDSKVEVIELQDVGCEERPWGSSSD", "length": 1434, "header": "tr|A0A9J7JIV1-1|A0A9J7JIV1_CRIGR Isoform 1 of Protein patched homolog 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ptch1 PE=3 SV=1 CANONICAL=A0A9J7JIV1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FQB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1/entry#A0A9J7FQB6-1", "sequence": { "sequence": "MFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLHKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDVALVLNGGCQGLSRKYMHWQEELIVGGTVKNATGKLVSARALQTMFQLMTPKQMYEHFRGYEYVSHINWNEDRAAAILEAWQRTYVEVVHQSVAPNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTEPHSNTRYSPPPPYSSHSFAHETHITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVILLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHKSFSNVKYVMLEENKQLPQMWLHYFRDWLQGLQDAFDSDWETGRIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRVICNNYTSLGLSSYPNGYPFLFWEQYISLRHWLLLAISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNHRAMLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTVLGVLNGLVLLPVLLSFFGPCPEVSPANGLNRLPTPSPEPPPSVVRFAVPPGHMNNGSDSSDSEYSSQTTVSGISEELRHYEAQQGSGGPGHQVIVEATENPVFARSTVVHPESRHHPPLNPRQQPHLDSGSLSPGRQGQQPRRDPPREGLRPPPYRPRRDAFEISTEGHSGPSNRDRSGPRGARSYNPRNPTSTAMGSSVPSYGQPITTVTASASVTVAVHPPPGPGRNPRGGPCPGYESYPETDHGVFQDPHVPFHVRCERRDSKVEVIELQDVGCEERPWGSSSD", "length": 1297, "header": "tr|A0A9J7FQB6-1|A0A9J7JIV1_CRIGR Computationally mapped isoform of Protein patched homolog 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ptch1 PE=3 SV=1 CANONICAL=A0A9J7JIV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1/entry#A0A9J7GXL6-1", "sequence": { "sequence": "MASAGNAAGALGRQAGGGRRRRTGGPHRAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLHKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDVALVLNGGCQGLSRKYMHWQEELIVGGTVKNATGKLVSARALQTMFQLMTPKQMYEHFRGYEYVSHINWNEDRAAAILEAWQRTYVEVVHQSVAPNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTEPHSNTRYSPPPPYSSHSFAHETHITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVILLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHKSFSNVKYVMLEENKQLPQMWLHYFRDWLQGLQDAFDSDWETGRIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRVICNNYTSLGLSSYPNGYPFLFWEQYISLRHWLLLAISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNHRAMLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTVLGVLNGLVLLPVLLSFFGPCPEVSPANGLNRLPTPSPEPPPSVVRFAVPPGHMNNGSDSSDSEYSSQTTVSGISEELRHYEAQQGSGGPGHQVIVEATENPVFARSTVVHPESRHHPPLNPRQQPHLDSGSLSPGRQGQQPRRDPPREGLRPPPYRPRRDAFEISTEGHSGPSNRDRSGPRGARSYNPRNPTSTAMGSSVPSYGQPITTVTASASVTVAVHPPPGPGRNPRGGPCPGYESYPETDHGVFQDPHVPFHVRCERRDSKVEVIELQDVGCEERPWGSSSD", "length": 1382, "header": "tr|A0A9J7GXL6-1|A0A9J7GXL6_CRIGR Computationally mapped isoform of Protein patched homolog 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Ptch1 PE=3 SV=1 CANONICAL=A0A9J7JIV1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1/entry#A0A9J7JIV1-1", "sequence": { "sequence": "MASAGNAAGALGRQAGGGRRRRTGGPHRAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLHKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDVALVLNGGCQGLSRKYMHWQEELIVGGTVKNATGKLVSARALQTMFQLMTPKQMYEHFRGYEYVSHINWNEDRAAAILEAWQRTYVEVVHQSVAPNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTEPHSNTRYSPPPPYSSHSFAHETHITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVILLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHKSFSNVKYVMLEENKQLPQMWLHYFRDWLQGLQDAFDSDWETGRIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRVICNNYTSLGLSSYPNGYPFLFWEQYISLRHWLLLAISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNHRAMLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTVLGVLNGLVLLPVLLSFFGPCPEVSPANGLNRLPTPSPEPPPSVVRFAVPPGHMNNGSDSSDSEYSSQTTVSGISEELRHYEAQQGSGGPGHQVIVEATENPVFARSTVVHPESRHHPPLNPRQQPHLDSGSLSPGRQGQQPRRDPPREGLRPPPYRPRRDAFEISTEGHSGPSNRDRSGPRGARSYNPRNPTSTAMGSSVPSYGQPITTVTASASVTVAVHPPPGPGRNPRGGPCPGYESYPETDHGVFQDPHVPFHVRCERRDSKVEVIELQDVGCEERPWGSSSD", "length": 1434, "header": "tr|A0A9J7JIV1-1|A0A9J7JIV1_CRIGR Isoform 1 of Protein patched homolog 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ptch1 PE=3 SV=1 CANONICAL=A0A9J7JIV1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1181, "start_aa": "Thr", "end_pos": 1181, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1181", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQB6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FQB6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQB6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763926", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763926", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "hedgehog family protein binding", "id": "GO:0097108", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097108", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" } ], "pmid": "" }, { "name": "hedgehog receptor activity", "id": "GO:0008158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008158", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" } ], "pmid": "" }, { "name": "smoothened binding", "id": "GO:0005119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005119", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of epidermal cell differentiation", "id": "GO:0045606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045606", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" } ], "pmid": "" }, { "name": "cell fate determination", "id": "GO:0001709", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001709", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" } ], "pmid": "" }, { "name": "epidermal cell fate specification", "id": "GO:0009957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009957", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" } ], "pmid": "" }, { "name": "negative regulation of smoothened signaling pathway", "id": "GO:0045879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045879", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1202, "end_pos": 1204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" }, { "start_pos": 861, "end_pos": 863, "annotation": "n_glycosylation_sequon" }, { "start_pos": 986, "end_pos": 988, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JIV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIV1" }, { "id": "PS50156", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SSD", "eco_id": "ECO_0000259", "start_pos": 424, "end_pos": 584, "start_aa": "Ser", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1181 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1202, "end_pos": 1204 }, { "start_pos": 127, "end_pos": 129 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 400, "end_pos": 402 }, { "start_pos": 541, "end_pos": 543 }, { "start_pos": 861, "end_pos": 863 }, { "start_pos": 986, "end_pos": 988 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266485" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Banp", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5", "locus": {} } ], "crossref": [ { "id": "A0A9J7JJI5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JJI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768192", "url": "https://www.ncbi.nlm.nih.gov/gene/100768192", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768192", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768192", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JJI5", "url": "https://www.orthodb.org/?gene=A0A9J7JJI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7K5P3", "url": "https://www.orthodb.org/?gene=A0A9J7K5P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16243:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16243:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266485", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FRC4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRM8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JF42", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JF42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JF42-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JF42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JLH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JM79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JM79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JM79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JM79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5P3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5P3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVRRLRASTRPGCGLRAGSAGRRGTSGRGPAAELTFGSGASAPPRPAPGGPVTSSARGRGLPRSATPVCRSRALRGAPGPCAPPCRLRWPHLSVTESAYPETSGFLLIGVPPLLVFWMMSEQDLADVVQIAVEDLSPDHPVVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNNDRQNAIVAKMEDPLSNRAPDSLENIISNAVPGRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQPQALHYALANAQQVQIHQIGEDGQVQVIPQGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQSWGLCQNPIPVSGDSVAQANPSQLWPLGGDTLDLPAGNEMIQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTATAQTAEALQPTLQPEMQLEHGAIQIQ", "length": 666, "header": "tr|A0A9J7JJI5-1|A0A9J7JJI5_CRIGR Isoform 1 of Protein BANP OS=Cricetulus griseus OX=10029 GN=Banp PE=3 SV=1 CANONICAL=A0A9J7JJI5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FRC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5/entry#A0A9J7FRC4-1", "sequence": { "sequence": "MSVRRLRASTRPGCGLRAGSAGRRGTSGRGPAAELTFGSGASAPPRPAPGGPVTSSARGRGLPRSATPVCRSRALRGAPGPCAPPCRLRWPHLSVTESAYPETSGFLLIGVPPLLVFWMMSEQDLADVVQIAVEDLSPDHPVVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNNDRQNAIVAKMEDPLSNRAPDSLENIISNAVPGRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQPQALHYALANAQQVQIHQIGEDGQVQVGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTATAQTAEALQPTLQPEMQLEHGAIQIQ", "length": 621, "header": "tr|A0A9J7FRC4-1|A0A9J7JJI5_CRIGR Computationally mapped isoform of Protein BANP OS=Cricetulus griseus OX=10029 GN=Banp PE=3 SV=1 CANONICAL=A0A9J7JJI5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5/entry#A0A9J7FRM8-1", "sequence": { "sequence": "MSVRRLRASTRPGCGLRAGSAGRRGTSGRGPAAELTFGSGASAPPRPAPGGPVTSSARGRGLPRSATPVCRSRALRGAPGPCAPPCRLRWPHLSVTESAYPETSGFLLIGVPPLLVFWMMSEQDLADVVQIAVEDLSPDHPVVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNNDRQNAIVAKMEDPLSNRAPDSLENIISNAVPGRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQPQALHYALANAQQVQIHQIGEDGQVQVGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQSWGLCQNPIPVSGDSVAQANPSQLWPLGGDTLDLPAGNEMIQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTATAQTAEALQPTLQPEMQLEHGAIQIQ", "length": 663, "header": "tr|A0A9J7FRM8-1|A0A9J7JJI5_CRIGR Computationally mapped isoform of Protein BANP OS=Cricetulus griseus OX=10029 GN=Banp PE=3 SV=1 CANONICAL=A0A9J7JJI5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5/entry#A0A9J7FTF5-1", "sequence": { "sequence": "MSVRRLRASTRPGCGLRAGSAGRRGTSGRGPAAELTFGSGASAPPRPAPGGPVTSSARGRGLPRSATPVCRSRALRGAPGPCAPPCRLRWPHLSVTESAYPETSGFLLIGVPPLLVFWMMSEQDLADVVQIAVEDLSPDHPVVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCAVPGRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQPQALHYALANAQQVQIHQIGEDGQVQVGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTATAQTAEALQPTLQPEMQLEHGAIQIQ", "length": 582, "header": "tr|A0A9J7FTF5-1|A0A9J7JJI5_CRIGR Computationally mapped isoform of Protein BANP OS=Cricetulus griseus OX=10029 GN=Banp PE=3 SV=1 CANONICAL=A0A9J7JJI5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JF42-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5/entry#A0A9J7JF42-1", "sequence": { "sequence": "MSVRRLRASTRPGCGLRAGSAGRRGTSGRGPAAELTFGSGASAPPRPAPGGPVTSSARGRGLPRSATPVCRSRALRGAPGPCAPPCRLRWPHLSVTESAYPETSGFLLIGVPPLLVFWMMSEQDLADVVQIAVEDLSPDHPVVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCAVPGRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQPQALHYALANAQQVQIHQIGEDGQVQVIPQGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQSWGLCQNPIPVSGDSVAQANPSQLWPLGGDTLDLPAGNEMIQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTATAQTAEALQPTLQPEMQLEHGAIQIQ", "length": 627, "header": "tr|A0A9J7JF42-1|A0A9J7JF42_CRIGR Computationally mapped isoform of Protein BANP OS=Cricetulus griseus OX=10029 GN=Banp PE=3 SV=1 CANONICAL=A0A9J7JJI5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5/entry#A0A9J7JJI5-1", "sequence": { "sequence": "MSVRRLRASTRPGCGLRAGSAGRRGTSGRGPAAELTFGSGASAPPRPAPGGPVTSSARGRGLPRSATPVCRSRALRGAPGPCAPPCRLRWPHLSVTESAYPETSGFLLIGVPPLLVFWMMSEQDLADVVQIAVEDLSPDHPVVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNNDRQNAIVAKMEDPLSNRAPDSLENIISNAVPGRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQPQALHYALANAQQVQIHQIGEDGQVQVIPQGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQSWGLCQNPIPVSGDSVAQANPSQLWPLGGDTLDLPAGNEMIQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTATAQTAEALQPTLQPEMQLEHGAIQIQ", "length": 666, "header": "tr|A0A9J7JJI5-1|A0A9J7JJI5_CRIGR Isoform 1 of Protein BANP OS=Cricetulus griseus OX=10029 GN=Banp PE=3 SV=1 CANONICAL=A0A9J7JJI5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JLH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5/entry#A0A9J7JLH4-1", "sequence": { "sequence": "MSVRRLRASTRPGCGLRAGSAGRRGTSGRGPAAELTFGSGASAPPRPAPGGPVTSSARGRGLPRSATPVCRSRALRGAPGPCAPPCRLRWPHLSVTESAYPETSGFLLIGVPPLLVFWMMSEQDLADVVQIAVEDLSPDHPVVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNNDRQNAIVAKMEDPLSNRAPDSLENIISNAVPGRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQPQALHYALANAQQVQIHQIGEDGQVQVIPQGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTATAQTAEALQPTLQPEMQLEHGAIQIQ", "length": 624, "header": "tr|A0A9J7JLH4-1|A0A9J7JLH4_CRIGR Computationally mapped isoform of Protein BANP OS=Cricetulus griseus OX=10029 GN=Banp PE=3 SV=1 CANONICAL=A0A9J7JJI5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JM79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5/entry#A0A9J7JM79-1", "sequence": { "sequence": "MSVRRLRASTRPGCGLRAGSAGRRGTSGRGPAAELTFGSGASAPPRPAPGGPVTSSARGRGLPRSATPVCRSRALRGAPGPCAPPCRLRWPHLSVTESAYPETSGFLLIGVPPLLVFWMMSEQDLADVVQIAVEDLSPDHPVVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCAVPGRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQPQALHYALANAQQVQIHQIGEDGQVQVGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQSWGLCQNPIPVSGDSVAQANPSQLWPLGGDTLDLPAGNEMIQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTATAQTAEALQPTLQPEMQLEHGAIQIQ", "length": 624, "header": "tr|A0A9J7JM79-1|A0A9J7JM79_CRIGR Computationally mapped isoform of Protein BANP OS=Cricetulus griseus OX=10029 GN=Banp PE=3 SV=1 CANONICAL=A0A9J7JJI5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5/entry#A0A9J7K5P3-1", "sequence": { "sequence": "MMSEQDLADVVQIAVEDLSPDHPVVLENHVVTDDDEPALKRQRLEINCQDPSIKSFLYSINQTICLRLDSIEAKLQALEATCKSLEEKLDLVTNKQHSPIQVPMVAGSPLGATQTCNKVRCVVPQTTVILNNDRQNAIVAKMEDPLSNRAPDSLENIISNAVPGRRQNTIVVKVPGQDDSHNEDGESGSEASDSVSNCGQPGSQNIGSNVTLITLNSEEDYPNGTWLGDENNPEMRVRCAIIPSDMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLTIYGIRCHLFYKFGITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPSSSSYSASETMMGTPPPTSELQQSQPQALHYALANAQQVQIHQIGEDGQVQVIPQGHLHIAQVPQGEQVQITQDSEGNLQIHHVGQDGQSWGLCQNPIPVSGDSVAQANPSQLWPLGGDTLDLPAGNEMIQVLQGAQLIAVASSDPAATGVDGSPLQGSDIQVQYVQLAPVSDHTATAQTAEALQPTLQPEMQLEHGAIQIQ", "length": 548, "header": "tr|A0A9J7K5P3-1|A0A9J7K5P3_CRIGR Computationally mapped isoform of Protein BANP OS=Cricetulus griseus OX=10029 GN=Banp PE=3 SV=1 CANONICAL=A0A9J7JJI5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FRC4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRC4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768192", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768192", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5" } ], "pmid": "" }, { "name": "protein localization to nucleus", "id": "GO:0034504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034504", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJI5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJI5" } ], "pmid": "" }, { "name": "negative regulation of protein catabolic process", "id": 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267238" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSP8#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7JK15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK15#function" }, { "database": "UniProtKB", "id": "A0A9J7JFL4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFL4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK15", "url": 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Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774561", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774561", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JK15", "url": "https://www.orthodb.org/?gene=A0A9J7JK15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF120", "url": 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"MAATVPSSHDLSGDFCLREEKVSSETMLTDCLTNYQELVSFKDVTVDFTQEEWTSLNPAQRSLYREVTLENYQNLASAGYQLIKPCLVSWLEQEEFSTGQKIVFPEWKMQLETKCLAPQQGVLKGSSISNGMQMQTESQNGRELYNWTKSGDFVNERSSLKTHTKTQTTQDNYHCSQYRKDFLMVQKKNCAGEKLCEFSQSEETCMIPVKANQKIASQEKSLECSDRGKSFINETQLQTHRRRTHNGDKLYDWNEYGRSFMNSRLAVLIETLNAKKPYRCKECGKGYRYPAYLNIHMRTHTGEKPYECKECGKAFNYSNSFQIHGRTHTGEKPYVCNQCGKAFTQYSGLSIHVRSHNGDKPYECKECGKAFLTSSRLIQHIRTHTGEKPFVCVKCGKAFAISSNLNGHLKMHAEEKTCECKICGKAFGYPSCLNNHMRTHSAKKSYTCKECGKAFNYSTHLKIHMRIHTGEKPYECKQCGKAFSHSTSLQIHERTHTGEKPYECKECGRAFICPSSFRIHEIGHTHTEEKPYKCQQCGKAYSHPRSLRRHERTH", "length": 554, "header": "tr|A0A9J7JK15-1|A0A9J7JK15_CRIGR Isoform 1 of Zinc finger protein 426 OS=Cricetulus griseus OX=10029 GN=LOC100774561 PE=3 SV=1 CANONICAL=A0A9J7JK15-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FSP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK15/entry#A0A9J7FSP8-1", "sequence": { "sequence": "MAATVPSSHDLSGDFCLREEKVSSETMLTDCLTNYQELVSFKDVTVDFTQEEWTSLNPAQRSLYREVTLENYQNLASAGYQLIKPCLVSWLEQEEFSTGQKIVFPEWKMQLETKCLAPQQGVLKGSSISNGMQMTESQNGRELYNWTKSGDFVNERSSLKTHTKTQTTQDNYHCSQYRKDFLMVQKKNCAGEKLCEFSQSEETCMIPVKANQKIASQEKSLECSDRGKSFINETQLQTHRRRTHNGDKLYDWNEYGRSFMNSRLAVLIETLNAKKPYRCKECGKGYRYPAYLNIHMRTHTGEKPYECKECGKAFNYSNSFQIHGRTHTGEKPYVCNQCGKAFTQYSGLSIHVRSHNGDKPYECKECGKAFLTSSRLIQHIRTHTGEKPFVCVKCGKAFAISSNLNGHLKMHAEEKTCECKICGKAFGYPSCLNNHMRTHSAKKSYTCKECGKAFNYSTHLKIHMRIHTGEKPYECKQCGKAFSHSTSLQIHERTHTGEKPYECKECGRAFICPSSFRIHEIGHTHTEEKPYKCQQCGKAYSHPRSLRRHERTH", "length": 553, "header": "tr|A0A9J7FSP8-1|A0A9J7JK15_CRIGR Computationally mapped isoform of Zinc finger protein 426 OS=Cricetulus griseus OX=10029 GN=LOC100774561 PE=3 SV=1 CANONICAL=A0A9J7JK15-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JFL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK15/entry#A0A9J7JFL4-1", "sequence": { "sequence": "MQLETKCLAPQQGVLKGSSISNGMQMQTESQNGRELYNWTKSGDFVNERSSLKTHTKTQTTQDNYHCSQYRKDFLMVQKKNCAGEKLCEFSQSEETCMIPVKANQKIASQEKSLECSDRGKSFINETQLQTHRRRTHNGDKLYDWNEYGRSFMNSRLAVLIETLNAKKPYRCKECGKGYRYPAYLNIHMRTHTGEKPYECKECGKAFNYSNSFQIHGRTHTGEKPYVCNQCGKAFTQYSGLSIHVRSHNGDKPYECKECGKAFLTSSRLIQHIRTHTGEKPFVCVKCGKAFAISSNLNGHLKMHAEEKTCECKICGKAFGYPSCLNNHMRTHSAKKSYTCKECGKAFNYSTHLKIHMRIHTGEKPYECKQCGKAFSHSTSLQIHERTHTGEKPYECKECGRAFICPSSFRIHEIGHTHTEEKPYKCQQCGKAYSHPRSLRRHERTH", "length": 446, "header": "tr|A0A9J7JFL4-1|A0A9J7JFL4_CRIGR Computationally mapped isoform of Zinc finger protein 426 OS=Cricetulus griseus OX=10029 GN=LOC100774561 PE=3 SV=1 CANONICAL=A0A9J7JK15-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JK15-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK15/entry#A0A9J7JK15-1", "sequence": { "sequence": "MAATVPSSHDLSGDFCLREEKVSSETMLTDCLTNYQELVSFKDVTVDFTQEEWTSLNPAQRSLYREVTLENYQNLASAGYQLIKPCLVSWLEQEEFSTGQKIVFPEWKMQLETKCLAPQQGVLKGSSISNGMQMQTESQNGRELYNWTKSGDFVNERSSLKTHTKTQTTQDNYHCSQYRKDFLMVQKKNCAGEKLCEFSQSEETCMIPVKANQKIASQEKSLECSDRGKSFINETQLQTHRRRTHNGDKLYDWNEYGRSFMNSRLAVLIETLNAKKPYRCKECGKGYRYPAYLNIHMRTHTGEKPYECKECGKAFNYSNSFQIHGRTHTGEKPYVCNQCGKAFTQYSGLSIHVRSHNGDKPYECKECGKAFLTSSRLIQHIRTHTGEKPFVCVKCGKAFAISSNLNGHLKMHAEEKTCECKICGKAFGYPSCLNNHMRTHSAKKSYTCKECGKAFNYSTHLKIHMRIHTGEKPYECKQCGKAFSHSTSLQIHERTHTGEKPYECKECGRAFICPSSFRIHEIGHTHTEEKPYKCQQCGKAYSHPRSLRRHERTH", "length": 554, "header": "tr|A0A9J7JK15-1|A0A9J7JK15_CRIGR Isoform 1 of Zinc finger protein 426 OS=Cricetulus griseus OX=10029 GN=LOC100774561 PE=3 SV=1 CANONICAL=A0A9J7JK15-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSP8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FSP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FSP8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774561", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774561", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK15" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK15" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK15" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK15" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JK15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JK15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JK15" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 222, "end_pos": 250, "start_aa": "Leu", "end_aa": "Leu", 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JGK0-1", "uniprot_ac": "A0A9J7JGK0", "uniprot_id": "A0A9J7JGK0_CRIGR", "mass": { "chemical_mass": 103848.0, "monoisotopic_mass": 103848.0 }, "refseq": { "ac": "XP_027268828", "name": "chordin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268828" }, "gene_names": [ { "name": "Chrd", "type": "recommended", "evidence": [ { "id": "A0A9J7JGK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0" } ] }, { "name": "Chrd", "type": "synonym", "evidence": [ { "id": "XP_027268828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268828" } ] } ], "protein_names": [ { "name": "Chordin", "type": "recommended", "evidence": [ { "id": "A0A9J7JGK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0/entry#names_and_taxonomy" } ] }, { "name": "chordin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027268828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268828" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268828" } ] }, { "annotation": "Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV04#function" }, { "database": "UniProtKB", "id": "PIRNR002496", "url": "https://www.uniprot.org/uniprotkb/PIRNR002496#function" }, { "database": "UniProtKB", "id": "A0A9J7JGK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0#function" }, { "database": "UniProtKB", "id": "A0A9J7GVH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVH0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Chrd", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0", "locus": {} } ], "crossref": [ { "id": "A0A9J7JGK0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JGK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100774612", "url": "https://www.ncbi.nlm.nih.gov/gene/100774612", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774612", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774612", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JGK0", "url": "https://www.orthodb.org/?gene=A0A9J7JGK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46526", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46526", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46526:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46526:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07452", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07452", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268828", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FV04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FV04-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSLPAPPAPRLLLGLLLLGSRPAGGTGPESPALPIRPEKEPLPVRGAAELGAGITARATGQRPPAKPVPTGCSFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWARRGRGPGRVSCKNIKPQCPTLACRQPRQLPGHCCQTCPQERSNLDRQPAGLVFEYPRDPEHRSYSDRGDPGAGERTRADGHTDFVALLTGPRSQAVARARVSLLRSSLRFSISYQRLDRPSRVRFTDPTGNILFEHPAAPTQDGLVCGVWRAMPRLSQRLLRAEQLHVALVTPTHPSGEVWGPLIWQGALAAETFSATLTLEGPQHRGVGGIALLTLSDTEDSLHFLLLFRGLLGPRNEGPAQVPLRLQILHQGQPLRELQANTSAEEPGFAEVLPSLTDQEMDWLVLGELQMVLERAGGPELRISGYITARRSCDVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKNQRTVLCHMAGLQLGGHMAVGICSGLGARGAHMLLQNELFLNIGTKDFPDGELRGHVTALSYSGHSARYDRLPVPLAGALVVPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGMPGPQRLLKGFYGSEAQGVVKDLEPMLLRHLAQGTASLLITTKSSPRGELRGQVHIASQCEAGGLRLVSEGVRMPVAPNGEAATSPAGPGPEAPAPAKHGSAGRPRDPNTCFFEGQQRPHGARWSPNYDPLCSLCTCQRRTVICDPIVCPPPSCPNPVQALDQCCPVCPEKQRSKDFPGLPNPEPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAICTCKGATGEVHCEKVQCPRLACAQPVRANPTDCCKQCPVGTGTPANLGDPMQADGPRGCRFAGQWFPENQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLSLSCGSGKESRCCSHCTAQRSTSETRTLPELEKEAESS", "length": 972, "header": "tr|A0A9J7JGK0-1|A0A9J7JGK0_CRIGR Isoform 1 of Chordin OS=Cricetulus griseus OX=10029 GN=Chrd PE=3 SV=1 CANONICAL=A0A9J7JGK0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FV04-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0/entry#A0A9J7FV04-1", "sequence": { "sequence": "MPSLPAPPAPRLLLGLLLLGSRPAGGTGPESPALPIRPEKEPLPVRGAAGCSFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWARRGRGPGRVSCKNIKPQCPTLACRQPRQLPGHCCQTCPQERSNLDRQPAGLVFEYPRDPEHRSYSDRGDPGAGERTRADGHTDFVALLTGPRSQAVARARVSLLRSSLRFSISYQRLDRPSRVRFTDPTGNILFEHPAAPTQDGLVCGVWRAMPRLSQRLLRAEQLHVALVTPTHPSGEVWGPLIWQGALAAETFSATLTLEGPQHRGVGGIALLTLSDTEDSLHFLLLFRGLLGPRNEGPAQVPLRLQILHQGQPLRELQANTSAEEPGFAEVLPSLTDQEMDWLVLGELQMVLERAGGPELRISGYITARRSCDVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKNQRTVLCHMAGLQLGGHMAVGICSGLGARGAHMLLQNELFLNIGTKDFPDGELRGHVTALSYSGHSARYDRLPVPLAGALVVPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGMPGPQRLLKGFYGSEAQGVVKDLEPMLLRHLAQGTASLLITTKSSPRGELRGQVHIASQCEAGGLRLVSEGVRMPVAPNGEAATSPAGPGPEAPAPAKHGSAGRPRDPNTCFFEGQQRPHGARWSPNYDPLCSLCTCQRRTVICDPIVCPPPSCPNPVQALDQCCPVCPEKQRSKDFPGLPNPEPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAICTCKGATGEVHCEKVQCPRLACAQPVRANPTDCCKQCPVGTGTPANLGDPMQADGPRGCRFAGQWFPENQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLSLSCGSGKESRCCSHCTAQRSTSETRTLPELEKEAESS", "length": 950, "header": "tr|A0A9J7FV04-1|A0A9J7JGK0_CRIGR Computationally mapped isoform of Chordin OS=Cricetulus griseus OX=10029 GN=Chrd PE=3 SV=1 CANONICAL=A0A9J7JGK0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0/entry#A0A9J7GVH0-1", "sequence": { "sequence": "MPSLPAPPAPRLLLGLLLLGSRPAGGTGPESPALPIRPEKEPLPVRGAAGCSFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWARRGRGPGRVSCKNIKPQCPTLACRQPRQLPGHCCQTCPQDAERSNLDRQPAGLVFEYPRDPEHRSYSDRGDPGAGERTRADGHTDFVALLTGPRSQAVARARVSLLRSSLRFSISYQRLDRPSRVRFTDPTGNILFEHPAAPTQDGLVCGVWRAMPRLSQRLLRAEQLHVALVTPTHPSGEVWGPLIWQGALAAETFSATLTLEGPQHRGVGGIALLTLSDTEDSLHFLLLFRGLLGPRNEGPAQVPLRLQILHQGQPLRELQANTSAEEPGFAEVLPSLTDQEMDWLVLGELQMVLERAGGPELRISGYITARRSCDVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKNQRTVLCHMAGLQLGGHMAVGICSGLGARGAHMLLQNELFLNIGTKDFPDGELRGHVTALSYSGHSARYDRLPVPLAGALVVPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGMPGPQRLLKGFYGSEAQGVVKDLEPMLLRHLAQGTASLLITTKSSPRGELRGQVHIASQCEAGGLRLVSEGVRMPVAPNGEAATSPAGPGPEAPAPAKHGSAGRPRDPNTCFFEGQQRPHGARWSPNYDPLCSLCTCQRRTVICDPIVCPPPSCPNPVQALDQCCPVCPEKQRSKDFPGLPNPEPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAICTCKGATGEVHCEKVQCPRLACAQPVRANPTDCCKQCPVGTGTPANLGDPMQADGPRGCRFAGQWFPENQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLSLSCGSGKESRCCSHCTAQRSTSETRTLPELEKEAESS", "length": 952, "header": "tr|A0A9J7GVH0-1|A0A9J7GVH0_CRIGR Computationally mapped isoform of Chordin OS=Cricetulus griseus OX=10029 GN=Chrd PE=3 SV=1 CANONICAL=A0A9J7JGK0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JGK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0/entry#A0A9J7JGK0-1", "sequence": { "sequence": "MPSLPAPPAPRLLLGLLLLGSRPAGGTGPESPALPIRPEKEPLPVRGAAELGAGITARATGQRPPAKPVPTGCSFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWARRGRGPGRVSCKNIKPQCPTLACRQPRQLPGHCCQTCPQERSNLDRQPAGLVFEYPRDPEHRSYSDRGDPGAGERTRADGHTDFVALLTGPRSQAVARARVSLLRSSLRFSISYQRLDRPSRVRFTDPTGNILFEHPAAPTQDGLVCGVWRAMPRLSQRLLRAEQLHVALVTPTHPSGEVWGPLIWQGALAAETFSATLTLEGPQHRGVGGIALLTLSDTEDSLHFLLLFRGLLGPRNEGPAQVPLRLQILHQGQPLRELQANTSAEEPGFAEVLPSLTDQEMDWLVLGELQMVLERAGGPELRISGYITARRSCDVLQSVLCGADALIPVQTGAAGSASFILLGNGSLIYQVQVVGTGSEVVAMTLETKPQRKNQRTVLCHMAGLQLGGHMAVGICSGLGARGAHMLLQNELFLNIGTKDFPDGELRGHVTALSYSGHSARYDRLPVPLAGALVVPPVRSQAAGHAWLSLDTHCHLHYEVLLAGLGGSEQGTVTAHLLGPPGMPGPQRLLKGFYGSEAQGVVKDLEPMLLRHLAQGTASLLITTKSSPRGELRGQVHIASQCEAGGLRLVSEGVRMPVAPNGEAATSPAGPGPEAPAPAKHGSAGRPRDPNTCFFEGQQRPHGARWSPNYDPLCSLCTCQRRTVICDPIVCPPPSCPNPVQALDQCCPVCPEKQRSKDFPGLPNPEPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAICTCKGATGEVHCEKVQCPRLACAQPVRANPTDCCKQCPVGTGTPANLGDPMQADGPRGCRFAGQWFPENQSWHPSVPPFGEMSCITCRCGAGVPHCERDDCSLSLSCGSGKESRCCSHCTAQRSTSETRTLPELEKEAESS", "length": 972, "header": "tr|A0A9J7JGK0-1|A0A9J7JGK0_CRIGR Isoform 1 of Chordin OS=Cricetulus griseus OX=10029 GN=Chrd PE=3 SV=1 CANONICAL=A0A9J7JGK0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV04" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FV04", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV04" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774612", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774612", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0" } ], "pmid": "" }, { "name": "negative regulation of BMP signaling pathway", "id": "GO:0030514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030514", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0" } ], "pmid": "" }, { "name": "dorsal/ventral pattern formation", "id": "GO:0009953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009953", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "BMP binding", "id": "GO:0036122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JGK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0" }, { "id": "PS50933", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50933" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CHRD", "eco_id": "ECO_0000259", "start_pos": 190, "end_pos": 299, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JGK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK0" }, { "id": "PS50184", "database": 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"monoisotopic_mass": 221631.0 }, "refseq": { "ac": "XP_027272107", "name": "HEAT repeat-containing protein 5A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272107" }, "gene_names": [ { "name": "Heatr5a", "type": "recommended", "evidence": [ { "id": "A0A9J7JIG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3" } ] }, { "name": "Heatr5a", "type": "synonym", "evidence": [ { "id": "XP_027272107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272107" } ] } ], "protein_names": [ { "name": "HEAT repeat-containing protein 5A", "type": "recommended", "evidence": [ { "id": "A0A9J7JIG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3/entry#names_and_taxonomy" } ] }, { "name": "HEAT repeat-containing protein 5A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027272107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272107" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272107" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Heatr5a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3", "locus": {} } ], "crossref": [ { "id": "100764339", "url": "https://www.ncbi.nlm.nih.gov/gene/100764339", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764339", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764339", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JIG3", "url": "https://www.orthodb.org/?gene=A0A9J7JIG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21663:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21663:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25468", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25468", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272107", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FYH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELAHSLLLNEEAFNQLGEVQKAEFIFEWLRHLEKLLLATSRNDVREKQKTLVEQLLSLLNSSPGPPTRKLLAQNLAILYSIGDTFSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILANAFTDTVGNILKAMKSAESQGRYEIMLSLQSILTGLGAAAAPCHRDIYKAARSCLTDRSMAVRCAAAKCLLELQNEAVFMWSTDLDSMATLCFKSFEGSNYDVRISVSKLLGTVLAKAVLAKHPGAAAPKQSARRTSLEEVLELLGTGFLRGSSGFLRASGDVLKGSSSVSKDVRVGVTQAYVVFVSTLGGAWLEKNFAIFLSHILSLVSQLNSKATQTQIDAVCCRRCVSFILRATIGGLLGEKAQIAAAKDICQAIWKLKKVVDAVLSDGNLETRLSSTDVAATQHTLVCALQELGNLIHSLGTTAAPLLQDSSTGLLDSVISVVLHPSISVRLAAAWCLHCIAVALPSQLTPLLDRCLERITTLKSSPEAVTGFSFAVAALLGAVTHCPLGIPHGKGKIIMALAEDLLCSAAQNSRLSLQRTQAGWLLIAAVMTLGPAVVSCHLARVLLLWKCVFPVSPKDLETEKSRGDSFTWQVTLEGRAGALCAVKSFISHCGDLLTEEVIQHLLPPLPCAVDLLTQLSSILKTYGNSLKTPSVVYRQRLYELLILLPPETYKGNLSAILKELAAELTAPDTQAAASTCLLPALCHPDDLLILSPLLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPVLSVISSASKLFGVVCANVEEAQRFQILEQLLNSIKHTKGARQQAVQLHIVCAVSNLLKYVAGSKRSLGPEVRRLVLTLVLGALESPNPLLRCAASEAWARLAQVVDDGVFTAGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGIGPQHLSSCIGVLYTLSQDSTSPDVQTWALHSLSLIIDSAGALYHVHVEPTLSLVTMLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNNTSVSTLRTSCLLGCAVMQDNPGCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCEILLDNSVLVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVLLARDSRDLAADTNIREVGLEGALLALLDKETDKSLCQDIRETLHHMLTSMAVEKLSLWLKLCKDVLAASADFAAVTCVDTMQEEEGDRGDDASVLTSRSDGKPHPFSNPRWATRVFAADCICRIIDQCENSNSAHFDIALAQEMKKSDSRNDFLVLHLSDLIRMAFMAATDHSDQLRLSGLDTLLLVIRRFADIAEPEFPGHVILEQYQANVGAALRPAFTSETPPDITAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLTKVQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKSHKQTLKAAVNPEDSVKSGSPPADGLLDLVCTDLGTLSRLWLAALQDFAVLTLPAEFASQLPVEGGAFYTAETSENARLHYHSSWALILHAAALWLTSTGFADPDEGAANLSRPVTPTSMCQGSSSSGAAVKSPEDVYTDRVHLILGISVEFLCSLRSDATMESLASCLHALQALLDAPWPRSKIGSDQDLGIELLNVLHRVILTRESPAIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGASEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGGPRVKAAKPQTLSEEGSKLVTAALVILAELPAVCSPEGSISILPTILYLAIGVLRETAVKLPGGQLSSTVTASLQALKGILTSPMARAEKSHAAWTSLLQNALATVLDCWSPVDGEHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIEKFKAALESKDPVVQMKTYQLLHSIFQFPNPAISYPYIYSLASSIVEKLQEIDKRKPEDTAELQIFQEGIKVLEALVTIAEEQHRSQLVACLLPVLISFLLEENALGSATSVMRSLHDFALQNLMQIGPRYSSVFRNVMASSPAMRARLEAAVKGNQESVRVEPPSKHAKNLGRNSSIQLKTNFL", "length": 2050, "header": "tr|A0A9J7JIG3-1|A0A9J7JIG3_CRIGR Isoform 1 of HEAT repeat-containing protein 5A OS=Cricetulus griseus OX=10029 GN=Heatr5a PE=3 SV=1 CANONICAL=A0A9J7JIG3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FYH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3/entry#A0A9J7FYH5-1", "sequence": { "sequence": "MELAHSLLLNEEAFNQLGEVQKAEFIFEWLRHLEKLLLATSRNDVREKQKTLVEQLLSLLNSSPGPPTRKLLAQNLAILYSIGDTFSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILANAFTDTVGNILKAMKSAESQGRYEIMLSLQSILTGLGAAAAPCHRDIYKAARSCLTDRSMAVRCAAAKCLLELQNEAVFMWSTDLDSMATLCFKSFEGSNYDVRISVSKLLGTVLAKAVLAKHPGAAPKQSARRTSLEEVLELLGTGFLRGSSGFLRASGDVLKGSSSVSKDVRVGVTQAYVVFVSTLGGAWLEKNFAIFLSHILSLVSQLNSKATQTQIDAVCCRRCVSFILRATIGGLLGEKAQIAAAKDICQAIWKLKKVVDAVLSDGNLETRLSSTDVAATQHTLVCALQELGNLIHSLGTTAAPLLQDSSTGLLDSVISVVLHPSISVRLAAAWCLHCIAVALPSQLTPLLDRCLERITTLKSSPEAVTGFSFAVAALLGAVTHCPLGIPHGKGKIIMALAEDLLCSAAQNSRLSLQRTQAGWLLIAAVMTLGPAVVSCHLARVLLLWKCVFPVSPKDLETEKSRGDSFTWQVTLEGRAGALCAVKSFISHCGDLLTEEVIQHLLPPLPCAVDLLTQLSSILKTYGNSLKTPSVVYRQRLYELLILLPPETYKGNLSAILKELAAELTAPDTQAAASTCLLPALCHPDDLLILSPLLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPVLSVISSASKLFGVVCANVEEAQRFQILEQLLNSIKHTKGARQQAVQLHIVCAVSNLLKYVAGSKRSLGPEVRRLVLTLVLGALESPNPLLRCAASEAWARLAQVVDDGVFTAGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGIGPQHLSSCIGVLYTLSQDSTSPDVQTWALHSLSLIIDSAGALYHVHVEPTLSLVTMLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNNTSVSTLRTSCLLGCAVMQDNPGCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVLLARDSRDLAADTNIREVGLEGALLALLDKETDKSLCQDIRETLHHMLTSMAVEKLSLWLKLCKDVLAASADFAAVTCVDTMQEEEGDRGDDASVLTSRSDGKPHPFSNPRWATRVFAADCICRIIDQCENSNSAHFDIALAQEMKKSDSRNDFLVLHLSDLIRMAFMAATDHSDQLRLSGLDTLLLVIRRFADIAEPEFPGHVILEQYQANVGAALRPAFTSETPPDITAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLTKVQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKSHKQTLKAAVNPEDSVKSGSPPADGLLDLVCTDLGTLSRLWLAALQDFAVLTLPAEFASQLPVEGGAFYTAETSENARLHYHSSWALILHAAALWLTSTGFADPDEGAANLSRPVTPTSMCQGSSSSGAAVKSPEDVYTDRVHLILGISVEFLCSLRSDATMESLASCLHALQALLDAPWPRSKIGSDQDLGIELLNVLHRVILTRESPAIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGASEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGGPRVKAAKPQTLSEEGSKLVTAALVILAELPAVCSPEGSISILPTILYLAIGVLRETAVKLPGGQLSSTVTASLQALKGILTSPMARAEKSHAAWTSLLQNALATVLDCWSPVDGEHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIEKFKAALESKDPVVQMKTYQLLHSIFQFPNPAISYPYIYSLASSIVEKLQEIDKRKPEDTAELQIFQEGIKVLEALVTIAEEQHRSQLVACLLPVLISFLLEENALGSATSVMRSLHDFALQNLMQIGPRYSSVFRNVMASSPAMRARLEAAVKGNQESVRVEPPSKHAKNLGRNSSIQLKTNFL", "length": 2040, "header": "tr|A0A9J7FYH5-1|A0A9J7JIG3_CRIGR Computationally mapped isoform of HEAT repeat-containing protein 5A OS=Cricetulus griseus OX=10029 GN=Heatr5a PE=3 SV=1 CANONICAL=A0A9J7JIG3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3/entry#A0A9J7FZ24-1", "sequence": { "sequence": "MELAHSLLLNEEAFNQLGEVQKAEFIFEWLRHLEKLLLATSRNDVREKQKTLVEQLLSLLNSSPGPPTRKLLAQNLAILYSIGDTFSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILANAFTDTVGNILKAMKSAESQGRYEIMLSLQSILTGLGAAAAPCHRDIYKAARSCLTDRSMAVRCAAAKCLLELQNEAVFMWSTDLDSMATLCFKSFEGSNYDVRISVSKLLGTVLAKAVLAKHPGAAPKQSARRTSLEEVLELLGTGFLRGSSGFLRASGDVLKGSSSVSKDVRVGVTQAYVVFVSTLGGAWLEKNFAIFLSHILSLVSQLNSKATQTQIDAVCCRRCVSFILRATIGGLLGEKAQIAAAKDICQAIWKLKKVVDAVLSDGNLETRLSSTDVAATQHTLVCALQELGNLIHSLGTTAAPLLQDSSTGLLDSVISVVLHPSISVRLAAAWCLHCIAVALPSQLTPLLDRCLERITTLKSSPEAVTGFSFAVAALLGAVTHCPLGIPHGKGKIIMALAEDLLCSAAQNSRLSLQRTQAGWLLIAAVMTLGPAVVSCHLARVLLLWKCVFPVSPKDLETEKSRGDSFTWQVTLEGRAGALCAVKSFISHCGDLLTEEVIQHLLPPLPCAVDLLTQLSSILKTYGNSLKTPSVVYRQRLYELLILLPPETYKGNLSAILKELAAELTAPDTQAAASTCLLPALCHPDDLLILSPLLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPVLSVISSASKLFGVVCANVEEAQRFQILEQLLNSIKHTKGARQQAVQLHIVCAVSNLLKYVAGSKRSLGPEVRRLVLTLVLGALESPNPLLRCAASEAWARLAQVVDDGVFTAGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGIGPQHLSSCIGVLYTLSQDSTSPDVQTWALHSLSLIIDSAGALYHVHVEPTLSLVTMLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNNTSVSTLRTSCLLGCAVMQDNPGCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCEILLDNSVLVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVLLARDSRDLAADTNIREVGLEGALLALLDKETDKSLCQDIRETLHHMLTSMAVEKLSLWLKLCKDVLAASADFAAVTCVDTMQEEEGDRGDDASVLTSRSDGKPHPFSNPRWATRVFAADCICRIIDQCENSNSAHFDIALAQEMKKSDSRNDFLVLHLSDLIRMAFMAATDHSDQLRLSGLDTLLLVIRRFADIAEPEFPGHVILEQYQANVGAALRPAFTSETPPDITAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLTKVQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKSHKQTLKAAVNPEDSVKSGSPPADGLLDLVCTDLGTLSRLWLAALQDFAVLTLPAEFASQLPVEGGAFYTAETSENARLHYHSSWALILHAAALWLTSTGFADPDEGAANLSRPVTPTSMCQGSSSSGAAVKSPEDVYTDRVHLILGISVEFLCSLRSDATMESLASCLHALQALLDAPWPRSKIGSDQDLGIELLNVLHRVILTRESPAIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGASEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGGPRVKAAKPQTLSEEGSKLVTAALVILAELPAVCSPEGSISILPTILYLAIGVLRETAVKLPGGQLSSTVTASLQALKGILTSPMARAEKSHAAWTSLLQNALATVLDCWSPVDGEHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIEKFKAALESKDPVVQMKTYQLLHSIFQFPNPAISYPYIYSLASSIVEKLQEIDKRKPEDTAELQIFQEGIKVLEALVTIAEEQHRSQLVACLLPVLISFLLEENALGSATSVMRSLHDFALQNLMQIGPRYSSVFRNVMASSPAMRARLEAAVKGNQESVRVEPPSKHAKNLGRNSSIQLKTNFL", "length": 2049, "header": "tr|A0A9J7FZ24-1|A0A9J7JIG3_CRIGR Computationally mapped isoform of HEAT repeat-containing protein 5A OS=Cricetulus griseus OX=10029 GN=Heatr5a PE=3 SV=1 CANONICAL=A0A9J7JIG3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3/entry#A0A9J7FZZ5-1", "sequence": { "sequence": "MELAHSLLLNEEAFNQLGEVQKAEFIFEWLRHLEKLLLATSRNDVREKQKTLVEQLLSLLNSSPGPPTRKLLAQNLAILYSIGDTFSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILANAFTDTVGNILKAMKSAESQGRYEIMLSLQSILTGLGAAAAPCHRDIYKAARSCLTDRSMAVRCAAAKCLLELQNEAVFMWSTDLDSMATLCFKSFEGSNYDVRISVSKLLGTVLAKAVLAKHPGAAAPKQSARRTSLEEVLELLGTGFLRGSSGFLRASGDVLKGSSSVSKDVRVGVTQAYVVFVSTLGGAWLEKNFAIFLSHILSLVSQLNSKATQTQIDAVCCRRCVSFILRATIGGLLGEKAQIAAAKDICQAIWKLKKVVDAVLSDGNLETRLSSTDVAATQHTLVCALQELGNLIHSLGTTAAPLLQDSSTGLLDSVISVVLHPSISVRLAAAWCLHCIAVALPSQLTPLLDRCLERITTLKSSPEAVTGFSFAVAALLGAVTHCPLGIPHGKGKIIMALAEDLLCSAAQNSRLSLQRTQAGWLLIAAVMTLGPAVVSCHLARVLLLWKCVFPVSPKDLETEKSRGDSFTWQVTLEGRAGALCAVKSFISHCGDLLTEEVIQHLLPPLPCAVDLLTQLSSILKTYGNSLKTPSVVYRQRLYELLILLPPETYKGNLSAILKELAAELTAPDTQAAASTCLLPALCHPDDLLILSPLLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPVLSVISSASKLFGVVCANVEEAQRFQILEQLLNSIKHTKGARQQAVQLHIVCAVSNLLKYVAGSKRSLGPEVRRLVLTLVLGALESPNPLLRCAASEAWARLAQVVDDGVFTAGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGIGPQHLSSCIGVLYTLSQDSTSPDVQTWALHSLSLIIDSAGALYHVHVEPTLSLVTMLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNNTSVSTLRTSCLLGCAVMQDNPGCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVLLARDSRDLAADTNIREVGLEGALLALLDKETDKSLCQDIRETLHHMLTSMAVEKLSLWLKLCKDVLAASADFAAVTCVDTMQEEEGDRGDDASVLTSRSDGKPHPFSNPRWATRVFAADCICRIIDQCENSNSAHFDIALAQEMKKSDSRNDFLVLHLSDLIRMAFMAATDHSDQLRLSGLDTLLLVIRRFADIAEPEFPGHVILEQYQANVGAALRPAFTSETPPDITAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLTKVQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKSHKQTLKAAVNPEDSVKSGSPPADGLLDLVCTDLGTLSRLWLAALQDFAVLTLPAEFASQLPVEGGAFYTAETSENARLHYHSSWALILHAAALWLTSTGFADPDEGAANLSRPVTPTSMCQGSSSSGAAVKSPEDVYTDRVHLILGISVEFLCSLRSDATMESLASCLHALQALLDAPWPRSKIGSDQDLGIELLNVLHRVILTRESPAIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGASEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGGPRVKAAKPQTLSEEGSKLVTAALVILAELPAVCSPEGSISILPTILYLAIGVLRETAVKLPGGQLSSTVTASLQALKGILTSPMARAEKSHAAWTSLLQNALATVLDCWSPVDGEHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIEKFKAALESKDPVVQMKTYQLLHSIFQFPNPAISYPYIYSLASSIVEKLQEIDKRKPEDTAELQIFQEGIKVLEALVTIAEEQHRSQLVACLLPVLISFLLEENALGSATSVMRSLHDFALQNLMQIGPRYSSVFRNVMASSPAMRARLEAAVKGNQESVRVEPPSKHAKNLGRNSSIQLKTNFL", "length": 2041, "header": "tr|A0A9J7FZZ5-1|A0A9J7JIG3_CRIGR Computationally mapped isoform of HEAT repeat-containing protein 5A OS=Cricetulus griseus OX=10029 GN=Heatr5a PE=3 SV=1 CANONICAL=A0A9J7JIG3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3/entry#A0A9J7JIG3-1", "sequence": { "sequence": "MELAHSLLLNEEAFNQLGEVQKAEFIFEWLRHLEKLLLATSRNDVREKQKTLVEQLLSLLNSSPGPPTRKLLAQNLAILYSIGDTFSVYETIDKCNDLIRSKDDSPSYLPTKLAAVVCLGSLYKKLGRILANAFTDTVGNILKAMKSAESQGRYEIMLSLQSILTGLGAAAAPCHRDIYKAARSCLTDRSMAVRCAAAKCLLELQNEAVFMWSTDLDSMATLCFKSFEGSNYDVRISVSKLLGTVLAKAVLAKHPGAAAPKQSARRTSLEEVLELLGTGFLRGSSGFLRASGDVLKGSSSVSKDVRVGVTQAYVVFVSTLGGAWLEKNFAIFLSHILSLVSQLNSKATQTQIDAVCCRRCVSFILRATIGGLLGEKAQIAAAKDICQAIWKLKKVVDAVLSDGNLETRLSSTDVAATQHTLVCALQELGNLIHSLGTTAAPLLQDSSTGLLDSVISVVLHPSISVRLAAAWCLHCIAVALPSQLTPLLDRCLERITTLKSSPEAVTGFSFAVAALLGAVTHCPLGIPHGKGKIIMALAEDLLCSAAQNSRLSLQRTQAGWLLIAAVMTLGPAVVSCHLARVLLLWKCVFPVSPKDLETEKSRGDSFTWQVTLEGRAGALCAVKSFISHCGDLLTEEVIQHLLPPLPCAVDLLTQLSSILKTYGNSLKTPSVVYRQRLYELLILLPPETYKGNLSAILKELAAELTAPDTQAAASTCLLPALCHPDDLLILSPLLQETDHRFIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPVLSVISSASKLFGVVCANVEEAQRFQILEQLLNSIKHTKGARQQAVQLHIVCAVSNLLKYVAGSKRSLGPEVRRLVLTLVLGALESPNPLLRCAASEAWARLAQVVDDGVFTAGLAQVSFDKLKSARDVVTRTGHSLALGSLHRYLGGIGPQHLSSCIGVLYTLSQDSTSPDVQTWALHSLSLIIDSAGALYHVHVEPTLSLVTMLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNNTSVSTLRTSCLLGCAVMQDNPGCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCEILLDNSVLVNLCSPYLLLRRAVLACLRQLVQREAAEVSEHAVLLARDSRDLAADTNIREVGLEGALLALLDKETDKSLCQDIRETLHHMLTSMAVEKLSLWLKLCKDVLAASADFAAVTCVDTMQEEEGDRGDDASVLTSRSDGKPHPFSNPRWATRVFAADCICRIIDQCENSNSAHFDIALAQEMKKSDSRNDFLVLHLSDLIRMAFMAATDHSDQLRLSGLDTLLLVIRRFADIAEPEFPGHVILEQYQANVGAALRPAFTSETPPDITAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLTKVQAGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKSHKQTLKAAVNPEDSVKSGSPPADGLLDLVCTDLGTLSRLWLAALQDFAVLTLPAEFASQLPVEGGAFYTAETSENARLHYHSSWALILHAAALWLTSTGFADPDEGAANLSRPVTPTSMCQGSSSSGAAVKSPEDVYTDRVHLILGISVEFLCSLRSDATMESLASCLHALQALLDAPWPRSKIGSDQDLGIELLNVLHRVILTRESPAIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGASEKETLPEFGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGGPRVKAAKPQTLSEEGSKLVTAALVILAELPAVCSPEGSISILPTILYLAIGVLRETAVKLPGGQLSSTVTASLQALKGILTSPMARAEKSHAAWTSLLQNALATVLDCWSPVDGEHQELDEVSLLTAITVFILSTSPEVTTIPCLQKRCIEKFKAALESKDPVVQMKTYQLLHSIFQFPNPAISYPYIYSLASSIVEKLQEIDKRKPEDTAELQIFQEGIKVLEALVTIAEEQHRSQLVACLLPVLISFLLEENALGSATSVMRSLHDFALQNLMQIGPRYSSVFRNVMASSPAMRARLEAAVKGNQESVRVEPPSKHAKNLGRNSSIQLKTNFL", "length": 2050, "header": "tr|A0A9J7JIG3-1|A0A9J7JIG3_CRIGR Isoform 1 of HEAT repeat-containing protein 5A OS=Cricetulus griseus OX=10029 GN=Heatr5a PE=3 SV=1 CANONICAL=A0A9J7JIG3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYH5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FYH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYH5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764339", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764339", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1019, "end_pos": 1021, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1020, "end_pos": 1022, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1065, "end_pos": 1067, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1395, "end_pos": 1397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1532, "end_pos": 1534, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2040, "end_pos": 2042, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1019, "end_pos": 1021 }, { "start_pos": 1020, "end_pos": 1022 }, { "start_pos": 1065, "end_pos": 1067 }, { "start_pos": 1395, "end_pos": 1397 }, { "start_pos": 1532, "end_pos": 1534 }, { "start_pos": 2040, "end_pos": 2042 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 692, "end_pos": 694 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"yes" } }, { "uniprot_canonical_ac": "A0A9J7JIC1-1", "uniprot_ac": "A0A9J7JIC1", "uniprot_id": "A0A9J7JIC1_CRIGR", "mass": { "chemical_mass": 43462.0, "monoisotopic_mass": 43462.0 }, "refseq": { "ac": "XP_027271936", "name": "replication factor C subunit 2 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271936" }, "gene_names": [ { "name": "Rfc2", "type": "recommended", "evidence": [ { "id": "A0A9J7JIC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ] }, { "name": "Rfc2", "type": "synonym", "evidence": [ { "id": "XP_027271936", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271936" } ] } ], "protein_names": [ { "name": "Replication factor C subunit 2", "type": "recommended", "evidence": [ { "id": "A0A9J7JIC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1/entry#names_and_taxonomy" } ] }, { "name": "replication factor C subunit 2 isoform X6", "type": "synonym", 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271936" } ] }, { "annotation": "Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA. This subunit binds ATP.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS1#function" }, { "database": "UniProtKB", "id": "ARBA00053246", "url": "https://www.uniprot.org/uniprotkb/ARBA00053246#function" }, { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1#function" }, { "database": "UniProtKB", "id": "A0A9J7JQ27", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQ27#function" }, { "database": "UniProtKB", "id": "A0A9J7JR72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR72#function" }, { "database": "UniProtKB", "id": "A0A8C2LN37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LN37#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rfc2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1", "locus": {} } ], "crossref": [ { "id": "A0A9J7JIC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JIC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00009", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00009", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18140", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18140", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770063", "url": "https://www.ncbi.nlm.nih.gov/gene/100770063", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": 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"Enzyme and Pathway" ] }, { "id": "A0A8C2LN37", "url": "https://www.orthodb.org/?gene=A0A8C2LN37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FZS1", "url": "https://www.orthodb.org/?gene=A0A9J7FZS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JIC1", "url": "https://www.orthodb.org/?gene=A0A9J7JIC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JQ27", "url": "https://www.orthodb.org/?gene=A0A9J7JQ27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11669", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11669", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11669:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11669:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08542", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08542", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271936", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271936", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LN37", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LN37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LN37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LN37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FZS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIC1", "url": 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"MEVQESGCDAAETRAQEPSPVPSKTAGGAGHYELPWVEKYRPIKLDEIVGNEDTVSRLEVFAKEGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIVSLAREPSLCCLCPEPIQSRCAVLRYTKLTDAQVLTRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKKMASGPQDWSYNCELLCGFWEWNPHPLEEQPVLLTTAISPAPMSCLTFRPTAKLSRLHLLNPQPPRTAPPAMKLIHRDSCSPMAPGLLTRRYHQQHFPSV", "length": 392, "header": "tr|A0A9J7JIC1-1|A0A9J7JIC1_CRIGR Isoform 1 of Replication factor C subunit 2 OS=Cricetulus griseus OX=10029 GN=Rfc2 PE=3 SV=1 CANONICAL=A0A9J7JIC1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LN37-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1/entry#A0A8C2LN37-1", "sequence": { "sequence": "MEVQESGCDAAETRAQEPSPVPSKTAGGAGHYELPWVEKYRPIKLDEIVGNEDTVSRLEVFAKEGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLTRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKILAHLWHLGYSPEDIISNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQKTMAPVAS", "length": 352, "header": "tr|A0A8C2LN37-1|A0A8C2LN37_CRIGR Computationally mapped isoform of Replication factor C subunit 2 OS=Cricetulus griseus OX=10029 GN=Rfc2 PE=3 SV=1 CANONICAL=A0A9J7JIC1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FZS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1/entry#A0A9J7FZS1-1", "sequence": { "sequence": "MEVQESGCDAAETRAQEPSPVPSKTAGGAGHYELPWVEKYRPIKLDEIVGNEDTVSRLEVFAKEGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIVSLAREPSLCCLCPEPIQSRCAVLRYTKLTDAQVLTRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKILAHLWHLGYSPEDIISNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQKTMAPVAS", "length": 339, "header": "tr|A0A9J7FZS1-1|A0A9J7JIC1_CRIGR Computationally mapped isoform of Replication factor C subunit 2 OS=Cricetulus griseus OX=10029 GN=Rfc2 PE=3 SV=1 CANONICAL=A0A9J7JIC1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1/entry#A0A9J7JIC1-1", "sequence": { "sequence": "MEVQESGCDAAETRAQEPSPVPSKTAGGAGHYELPWVEKYRPIKLDEIVGNEDTVSRLEVFAKEGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIVSLAREPSLCCLCPEPIQSRCAVLRYTKLTDAQVLTRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKKMASGPQDWSYNCELLCGFWEWNPHPLEEQPVLLTTAISPAPMSCLTFRPTAKLSRLHLLNPQPPRTAPPAMKLIHRDSCSPMAPGLLTRRYHQQHFPSV", "length": 392, "header": "tr|A0A9J7JIC1-1|A0A9J7JIC1_CRIGR Isoform 1 of Replication factor C subunit 2 OS=Cricetulus griseus OX=10029 GN=Rfc2 PE=3 SV=1 CANONICAL=A0A9J7JIC1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQ27-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1/entry#A0A9J7JQ27-1", "sequence": { "sequence": "MEVQESGCDAAETRAQEPSPVPSKTAGGAGHYELPWVEKYRPIKLDEIVGNEDTVSRLEVFAKEGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIVSLAREPSLCCLCPEPIQSRCAVLRYTKLTDAQVLTRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKILAHLWHLGYSPEDIISNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQKTMAPVAS", "length": 366, "header": "tr|A0A9J7JQ27-1|A0A9J7JQ27_CRIGR Computationally mapped isoform of Replication factor C subunit 2 OS=Cricetulus griseus OX=10029 GN=Rfc2 PE=3 SV=1 CANONICAL=A0A9J7JIC1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JR72-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1/entry#A0A9J7JR72-1", "sequence": { "sequence": "MEVQESGCDAAETRAQEPSPVPSKTAGGAGHYELPWVEKYRPIKLDEIVGNEDTVSRLEVFAKEGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLTRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKKMASGPQDWSYNCELLCGFWEWNPHPLEEQPVLLTTAISPAPMSCLTFRPTAKLSRLHLLNPQPPRTAPPAMKLIHRDSCSPMAPGLLTRRYHQQHFPSV", "length": 378, "header": "tr|A0A9J7JR72-1|A0A9J7JR72_CRIGR Computationally mapped isoform of Replication factor C subunit 2 OS=Cricetulus griseus OX=10029 GN=Rfc2 PE=3 SV=1 CANONICAL=A0A9J7JIC1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7FZS1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZS1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770063", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770063", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ], "pmid": "" }, { "name": "DNA clamp loader activity", "id": "GO:0003689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003689", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ], "pmid": "" }, { "name": "enzyme binding", "id": "GO:0019899", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019899", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ], "pmid": "" }, { "name": "single-stranded DNA helicase activity", "id": "GO:0017116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017116", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ], "pmid": "" }, { "name": "DNA replication factor C complex", "id": "GO:0005663", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005663", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIC1" } ], "pmid": "" }, { "name": "Ctf18 RFC-like complex", "id": "GO:0031390", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031390", "evidence": [ { "database": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JJC9-1", "uniprot_ac": "A0A9J7JJC9", "uniprot_id": "A0A9J7JJC9_CRIGR", "mass": { "chemical_mass": 37331.0, "monoisotopic_mass": 37331.0 }, "refseq": { "ac": "XP_027273756", "name": "calmodulin-lysine N-methyltransferase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273756" }, "gene_names": [ { "name": "Camkmt", "type": "recommended", "evidence": [ { "id": "A0A9J7JJC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9" } ] }, { "name": "Camkmt", "type": "synonym", "evidence": [ { "id": "XP_027273756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273756" } ] } ], "protein_names": [ { "name": "Calmodulin-lysine N-methyltransferase", "type": "recommended", "evidence": [ { "id": "A0A9J7JJC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9/entry#names_and_taxonomy" } ] }, { "name": "2.1.1.60", "type": "synonym", "evidence": [ { "id": "A0A9J7JJC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9/entry#names_and_taxonomy" } ] }, { "name": "calmodulin-lysine N-methyltransferase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027273756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273756" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273756" } ] }, { "annotation": "Catalyzes the trimethylation of 'Lys-116' in calmodulin.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0I0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0I0#function" }, { "database": "UniProtKB", "id": "ARBA00055351", "url": "https://www.uniprot.org/uniprotkb/ARBA00055351#function" }, { "database": "UniProtKB", "id": "A0A9J7G172", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G172#function" }, { "database": "UniProtKB", "id": "A0A9J7G1R5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1R5#function" }, { "database": "UniProtKB", "id": "A0A9J7G4R5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4R5#function" }, { "database": "UniProtKB", "id": "A0A9J7JJC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9#function" }, { "database": "UniProtKB", "id": "A0A9J7JSG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSG2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Camkmt", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9", "locus": {} } ], "crossref": [ { "id": "A0A9J7JJC9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JJC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766475", "url": "https://www.ncbi.nlm.nih.gov/gene/100766475", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766475", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766475", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JJC9", "url": "https://www.orthodb.org/?gene=A0A9J7JJC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13539", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13539", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13539:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13539:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273756", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "21556", "url": "https://www.rhea-db.org/rhea/21556", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G0I0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G0I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G172", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G172", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G172-1", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JR87-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESQVAASGAAGAAADAGERSRIGGASQGVPKGAARWKLLRQVLKQKQLDDCLKHVSVRRFESFNLFSVTEVKKRETEEEAGVWVQYTSVLYPEYSISLRHNSGPLNVEDILTSFDNTGNVCIWPSEEVLAYYCLKHRNMFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVNSIIESNQKTGVFKAQKVSSCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLRPTGKAMVFAPRRGNTFDQFCNLAEKAGFSLQRHENYDEHISNFHSKVALSYMAEFYDLNGTSIWGPVTLQCENAYSVLSLSRDLWPS", "length": 335, "header": "tr|A0A9J7JJC9-1|A0A9J7JJC9_CRIGR Isoform 1 of Calmodulin-lysine N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Camkmt PE=4 SV=1 CANONICAL=A0A9J7JJC9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G0I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9/entry#A0A9J7G0I0-1", "sequence": { "sequence": "MESQVAASGAAGAAADAGERSRIGGASQGVPKGAARWKLLRQVLKQKQLDDCLKHVSVRRFESFNLFSVTEVKKRETEEEAGVWVQYTSVLYPEYSISLRHNSGPLNVEDILTSFDNTGNVCIWPSEEVLAYYCLKHRNMFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVNSIIESNQKTGVFKAQKVSSCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLRPTVALSYMAEFYDLNGTSIWGPVTLQCENAYSVLSLSRDLWPS", "length": 291, "header": "tr|A0A9J7G0I0-1|A0A9J7JJC9_CRIGR Computationally mapped isoform of Calmodulin-lysine N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Camkmt PE=4 SV=1 CANONICAL=A0A9J7JJC9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G172-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9/entry#A0A9J7G172-1", "sequence": { "sequence": "MESQVAASGAAGAAADAGERSRIGGASQGVPKGAARWKLLRQVLKQKQLDDCLKHVSVRRFESFNLFSVTEVKKRETEEEAGVWVQYTSVLYPEYSISLRHNSGPLNVEDILTSFDNTGNVCIWPSEEVLAYYCLKHRNMFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVNSIIESNQKTGVFKAQKVSSCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLRPTGKAMVFAPRRGNTFDQFCNLAEKAGFSLQRHENYDEHISNFHSKQLSHCCIEKSLHCS", "length": 308, "header": "tr|A0A9J7G172-1|A0A9J7JJC9_CRIGR Computationally mapped isoform of Calmodulin-lysine N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Camkmt PE=4 SV=1 CANONICAL=A0A9J7JJC9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9/entry#A0A9J7G1R5-1", "sequence": { "sequence": "MESQVAASGAAGAAADAGERSRIGGASQGVPKGAARWKLLRQVLKQKQLDDCLKHVSVRRFESFNLFSVTEVKKRETEEEAGVWVQYTSVLYPEYSISLRHNSGPLNVEDILTSFDNTGNVCIWPSEEVLAYYCLKHRNMFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVNSIIESNQKTGVFKAQKVSSCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLRPTGKAMVFAPRRGNTFDQFCNLAEKAGFSLQRHENYDEHISNFHSKTNLQDARGGSLE", "length": 306, "header": "tr|A0A9J7G1R5-1|A0A9J7JJC9_CRIGR Computationally mapped isoform of Calmodulin-lysine N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Camkmt PE=4 SV=1 CANONICAL=A0A9J7JJC9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G4R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9/entry#A0A9J7G4R5-1", "sequence": { "sequence": "MESQVAASGAAGAAADAGERSRIGGASQGVPKGAARWKLLRQVLKQKQLDDCLKHVSVRRFESFNLFSVTEVKKRETEEEAGVWVQYTSVLYPEYSISLRHNSGPLNVEDILTSFDNTGNVCIWPSEEVLAYYCLKHRNMFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVNSIIESNQKTGVFKAQKVSSCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLRPTLKKENSDIYEENLHYPLLLTLTKMG", "length": 275, "header": "tr|A0A9J7G4R5-1|A0A9J7JJC9_CRIGR Computationally mapped isoform of Calmodulin-lysine N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Camkmt PE=4 SV=1 CANONICAL=A0A9J7JJC9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9/entry#A0A9J7JJC9-1", "sequence": { "sequence": "MESQVAASGAAGAAADAGERSRIGGASQGVPKGAARWKLLRQVLKQKQLDDCLKHVSVRRFESFNLFSVTEVKKRETEEEAGVWVQYTSVLYPEYSISLRHNSGPLNVEDILTSFDNTGNVCIWPSEEVLAYYCLKHRNMFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVNSIIESNQKTGVFKAQKVSSCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLRPTGKAMVFAPRRGNTFDQFCNLAEKAGFSLQRHENYDEHISNFHSKVALSYMAEFYDLNGTSIWGPVTLQCENAYSVLSLSRDLWPS", "length": 335, "header": "tr|A0A9J7JJC9-1|A0A9J7JJC9_CRIGR Isoform 1 of Calmodulin-lysine N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Camkmt PE=4 SV=1 CANONICAL=A0A9J7JJC9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JR87-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9/entry#A0A9J7JR87-1", "sequence": { "sequence": "MESQVAASGAAGAAADAGERSRIGGASQGVPKGAARWKLLRQVLKQKQLDDCLKHVSVRRFESFNLFSVTEVKKRETEEEAGVWVQYTSVLYPEYSISLRHNSGPLNVEDILTSFDNTGNVCIWPSEEVLAYYCLKHRNMFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVNSIIESNQKTGVFKAQKVSSCLFLDQYRASLVDAIKRLLRPTGKAMVFAPRRGNTFDQFCNLAEKAGFSLQRHENYDEHISNFHSKVALSYMAEFYDLNGTSIWGPVTLQCENAYSVLSLSRDLWPS", "length": 310, "header": "tr|A0A9J7JR87-1|A0A9J7JR87_CRIGR Computationally mapped isoform of Calmodulin-lysine N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Camkmt PE=4 SV=1 CANONICAL=A0A9J7JJC9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9/entry#A0A9J7JSG2-1", "sequence": { "sequence": "MESQVAASGAAGAAADAGERSRIGGASQGVPKGAARWKLLRQVLKQKQLDDCLKHVSVRRFESFNLFSVTEVKKRETEEEAGVWVQYTSVLYPEYSISLRHNSGPLNVEDILTSFDNTGNVCIWPSEEVLAYYCLKHRNMFRDLAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVNSIIESNQKTGVFKAQKVSSCVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLRPTGKAMVFAPRRGNTFDQFCNLAEKAGFSLQRHENYDEHISNFHSKLKKENSDIYEENLHYPLLLTLTKMG", "length": 319, "header": "tr|A0A9J7JSG2-1|A0A9J7JSG2_CRIGR Computationally mapped isoform of Calmodulin-lysine N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Camkmt PE=4 SV=1 CANONICAL=A0A9J7JJC9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9/entry#A0A9J7JSU9-1", "sequence": { "sequence": "MESQVAASGAAGAAADAGERSRIGGASQGVPKGAARWKLLRQVLKQKQLDDCLKHVSVRRFESFNLFSVTEVKKRETEEEAGVWVQYTSVLYPEYSISLRHNSGPLNVEDILTSFDNTGNVCIWPSEEVLAYYCLKHRNMFSVLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASLVDAIKRLLRPTGKAMVFAPRRGNTFDQFCNLAEKAGFSLQRHENYDEHISNFHSKVALSYMAEFYDLNGTSIWGPVTLQCENAYSVLSLSRDLWPS", "length": 273, "header": "tr|A0A9J7JSU9-1|A0A9J7JSU9_CRIGR Computationally mapped isoform of Calmodulin-lysine N-methyltransferase OS=Cricetulus griseus OX=10029 GN=Camkmt PE=4 SV=1 CANONICAL=A0A9J7JJC9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0I0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0I0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G0I0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G0I0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766475", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766475", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calmodulin-lysine N-methyltransferase activity", "id": "GO:0018025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018025", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "21556", "name": "", 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] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278389", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278389" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Celf1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75", "locus": {} } ], "crossref": [ { "id": "cd12631", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12631", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12634", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12634", "database": "CDD", 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"A0A9J7G779-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G779-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7U7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB75-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JM67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JM67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JM67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JM67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JVU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JVU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW02-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW02-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNGLRRKVDHLERRPASALGQTFLSSVGTRPRSVQLPRYCSPAASYDPAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLASLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 560, "header": "tr|A0A9J7GB75-1|A0A9J7GB75_CRIGR Isoform 1 of CUGBP Elav-like family member 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Celf1 PE=3 SV=1 CANONICAL=A0A9J7GB75-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M0W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75/entry#A0A8C2M0W3-1", "sequence": { "sequence": "MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLASLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 513, "header": "tr|A0A8C2M0W3-1|A0A8C2M0W3_CRIGR Computationally mapped isoform of CUGBP Elav-like family member 1 isoform X6 OS=Cricetulus griseus OX=10029 GN=Celf1 PE=3 SV=1 CANONICAL=A0A9J7GB75-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G6P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75/entry#A0A9J7G6P2-1", "sequence": { "sequence": "MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLASLNTLGPQYLALLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 509, "header": "tr|A0A9J7G6P2-1|A0A9J7GB75_CRIGR Computationally mapped isoform of CUGBP Elav-like family member 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Celf1 PE=3 SV=1 CANONICAL=A0A9J7GB75-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G779-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75/entry#A0A9J7G779-1", "sequence": { "sequence": "MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLASLNTLGPQYLALLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 510, "header": "tr|A0A9J7G779-1|A0A9J7GB75_CRIGR Computationally mapped isoform of CUGBP Elav-like family member 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Celf1 PE=3 SV=1 CANONICAL=A0A9J7GB75-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75/entry#A0A9J7G7U7-1", "sequence": { "sequence": "MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNGLRRKVDHLERRPASALGQTFLSSVGTRPRSVQLPRYCSPAASYDPAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLASLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 559, "header": "tr|A0A9J7G7U7-1|A0A9J7GB75_CRIGR Computationally mapped isoform of CUGBP Elav-like family member 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Celf1 PE=3 SV=1 CANONICAL=A0A9J7GB75-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB75-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75/entry#A0A9J7GB75-1", "sequence": { "sequence": "MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNGLRRKVDHLERRPASALGQTFLSSVGTRPRSVQLPRYCSPAASYDPAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLASLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 560, "header": "tr|A0A9J7GB75-1|A0A9J7GB75_CRIGR Isoform 1 of CUGBP Elav-like family member 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Celf1 PE=3 SV=1 CANONICAL=A0A9J7GB75-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JM67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75/entry#A0A9J7JM67-1", "sequence": { "sequence": "MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNGLRRKVDHLERRPASALGQTFLSSVGTRPRSVQLPRYCSPAASYDPAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLASLNTLGPQYLALLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 556, "header": "tr|A0A9J7JM67-1|A0A9J7JM67_CRIGR Computationally mapped isoform of CUGBP Elav-like family member 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Celf1 PE=3 SV=1 CANONICAL=A0A9J7GB75-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JVU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75/entry#A0A9J7JVU1-1", "sequence": { "sequence": "MNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNGLRRKVDHLERRPASALGQTFLSSVGTRPRSVQLPRYCSPAASYDPAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLASLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 533, "header": "tr|A0A9J7JVU1-1|A0A9J7JVU1_CRIGR Computationally mapped isoform of CUGBP Elav-like family member 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Celf1 PE=3 SV=1 CANONICAL=A0A9J7GB75-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JW02-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB75/entry#A0A9J7JW02-1", "sequence": { "sequence": "MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLASLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 469, "header": "tr|A0A9J7JW02-1|A0A9J7JW02_CRIGR Computationally mapped isoform of CUGBP Elav-like family member 1 isoform X9 OS=Cricetulus griseus OX=10029 GN=Celf1 PE=3 SV=1 CANONICAL=A0A9J7GB75-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6P2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6P2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6P2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6P2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760547", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760547", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1MC72-1", "protein_name": "CUGBP Elav-like family member 1", "gene_name": "CELF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTLQRYQDYKEAKAVYICGSDKCSKLISLASEGESEVMAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAVQLQNLAALAAAASAAQSTPSGTSALTTSSSPLSVLTSSGSSPSSSSSSSVNPIASLGALQTLAGATAGLNVSSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLAQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 550 }, "evidence": [ { "id": "A0A9J7GB75", "url": "https://omabrowser.org/oma/group/A0A9J7GB75/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P28659-1", "protein_name": "CUGBP Elav-like family member 1", "gene_name": "Celf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 486 }, "evidence": [ { "id": "A0A9J7GB75", "url": "https://omabrowser.org/oma/group/A0A9J7GB75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4QQT3-1", "protein_name": "CUGBP Elav-like family member 1", "gene_name": "Celf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTANSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 487 }, "evidence": [ { "id": "A0A9J7GB75", "url": "https://omabrowser.org/oma/group/A0A9J7GB75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54EJ3-1", "protein_name": "RNA-binding region RNP-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSTKLFVGQIPKSFNEEEIKNLFTNIANIESVSLIKNKTTNEPQGCAFVSVPSREEADRAIEQLHNSKKFQGVLNNLQVKYADSEQEKLASKLFVGMLPRSYEEEQIRELFEPHGVVEDICILRGPNSESKGCGFIKFDNRESALSAIATLNGMKLDGSPNPLVVKFADTEKDKKKKQKQQQIQIQMQQRQQQQQQQQQQPSHQQQQSHQQSFQSQYQQPVVNQFPPKMNQQPFIVNPYFGQMPNFNFIPSIDSSPSLLGTPPIIGDGIYDIYSNSQFDNKYNNNGGMGGNGGNNGNMYGRNFNNGNNGPMGGMNGNGMNNGGPMGNGMNNGGPMGNGMNNGGPMGNGMNNGGPMGNGMNGNGMNGNGMGGPMGNGMNNGMGGMNQGGPMGNKKNQSVGPQGSNLFVYNIPNYFSDNDLLGLFQQYGIVVSAKVYVDKNTGVSKGFGFVSYDNPASANLAISNLHGQMMAGKKLKVSLKQTSGQGSQPY", "length": 489 }, "evidence": [ { "id": "A0A9J7GB75", "url": "https://omabrowser.org/oma/group/A0A9J7GB75/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8LFS6-1", "protein_name": "RNA-binding protein BRN1", "gene_name": "BRN1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAEAKEENREKNEEEESVKLFVGQIPKHMSESQLLTLFQEFAVVDEVNIIKDKITRASRGCCFLLCPSREEADKLVNACHNKKTLPGANSLLQVKYADGELERLEHKLFVGMLPKNVSEAEVQSLFSKYGTIKDLQILRGAQQTSKGCAFLKYETKEQAVSAMESINGKHKMEGSTVPLVVKWADTERERHTRRLQKAQSHIARLGNGDPTNPSLFGALPMGYVPPYNGYGYHQPPGTYGYMLPPIQNQAAFSNMIAQPNQGNNNALQGTSPDSVPPRLARRNFPMPPGNYMGSGYPAMRGHPFPFAYPRGIVSPRPLSSSPGSISPGMSTPLGIGLSSVVQTEGPEGANLFIYNIPREFGDQELAAAFQSFGIVLSAKVFVDKATGVSKCFGFVSYDSQAAAQNAIDMMNGRHLGGKKLKVQLKRDSNNGQPSSNPSLIS", "length": 441 }, "evidence": [ { "id": "A0A9J7GB75", "url": "https://omabrowser.org/oma/group/A0A9J7GB75/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q92879-1", "protein_name": "CUGBP Elav-like family member 1", "gene_name": "CELF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGTLDHPDQPDLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALYLQLLQQTASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQYAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKPY", "length": 486 }, "evidence": [ { "id": "A0A9J7GB75", "url": "https://omabrowser.org/oma/group/A0A9J7GB75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9IBD0-1", "protein_name": "CUGBP Elav-like family member 1", "gene_name": "celf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"monoisotopic_mass": 37495.0 }, "refseq": { "ac": "XP_027277557", "name": "sperm flagellar protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277557" }, "gene_names": [ { "name": "Spef1", "type": "recommended", "evidence": [ { "id": "A0A9J7GB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49" } ] }, { "name": "Spef1", "type": "synonym", "evidence": [ { "id": "XP_027277557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277557" } ] } ], "protein_names": [ { "name": "Sperm flagellar protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7GB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49/entry#names_and_taxonomy" } ] }, { "name": "sperm flagellar protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027277557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277557" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277557" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Spef1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49", "locus": {} } ], "crossref": [ { "id": "A0A9J7GB49", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GB49", "database": "AlphaFoldDB", "categories": [] }, { "id": "100766382", "url": "https://www.ncbi.nlm.nih.gov/gene/100766382", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766382", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766382", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G6Q3", "url": "https://www.orthodb.org/?gene=A0A9J7G6Q3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GB49", "url": "https://www.orthodb.org/?gene=A0A9J7GB49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12509", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12509", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12509:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12509:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277557", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277557", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G6Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB49-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASSVDEEALHQLYLWIDNIPLSRPKRNLSRDFSDGVLVAELIKFYFPKMVEMHNYVPANSLQQKLSNWGHLNRKVLNKLNFSVPDDVMRKIAQCSPGVVELVLIPLRQRLEERQRRQKLGAGSLQELASQDGSGYMDIGLYQKARGDGAPALGGEQLRGGRPQAPRPPGYNQALPGDPSFVLQIAEKEQELLASQETVQVLQMKVKRLEHLLQLKNVRIEDLSRRLQQAERKQRRKDHFPQPRKPVRTHGMNSQSVPTLRLPALGLERRSSGSLLSLEDSPDSIYAISPWPWTFEKLSPEAEGFSYPSWVLTWDPSQGWRPQQLERKG", "length": 329, "header": "tr|A0A9J7GB49-1|A0A9J7GB49_CRIGR Isoform 1 of Sperm flagellar protein 1 OS=Cricetulus griseus OX=10029 GN=Spef1 PE=4 SV=1 CANONICAL=A0A9J7GB49-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G6Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49/entry#A0A9J7G6Q3-1", "sequence": { "sequence": "MASSVDEEALHQLYLWIDNIPLSRPKRNLSRDFSDGVLVAELIKFYFPKMVEMHNYVPANSLQQKLSNWGHLNRKVLNKLNFSVPDDVMRKIAQCSPGVVELVLIPLRQRLEERQRRQKLGAGSLQELASQDGSGYMDIGLYQKARGDGAPALGGEQLRGGRPQAPRPPGYNQALPGDPSFVLQIAEKEQELLASQETVQVLQMKVKRLEHLLQLKNVRIEDLSRRLQQAERKQR", "length": 235, "header": "tr|A0A9J7G6Q3-1|A0A9J7GB49_CRIGR Computationally mapped isoform of Sperm flagellar protein 1 OS=Cricetulus griseus OX=10029 GN=Spef1 PE=4 SV=1 CANONICAL=A0A9J7GB49-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB49-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49/entry#A0A9J7GB49-1", "sequence": { "sequence": "MASSVDEEALHQLYLWIDNIPLSRPKRNLSRDFSDGVLVAELIKFYFPKMVEMHNYVPANSLQQKLSNWGHLNRKVLNKLNFSVPDDVMRKIAQCSPGVVELVLIPLRQRLEERQRRQKLGAGSLQELASQDGSGYMDIGLYQKARGDGAPALGGEQLRGGRPQAPRPPGYNQALPGDPSFVLQIAEKEQELLASQETVQVLQMKVKRLEHLLQLKNVRIEDLSRRLQQAERKQRRKDHFPQPRKPVRTHGMNSQSVPTLRLPALGLERRSSGSLLSLEDSPDSIYAISPWPWTFEKLSPEAEGFSYPSWVLTWDPSQGWRPQQLERKG", "length": 329, "header": "tr|A0A9J7GB49-1|A0A9J7GB49_CRIGR Isoform 1 of Sperm flagellar protein 1 OS=Cricetulus griseus OX=10029 GN=Spef1 PE=4 SV=1 CANONICAL=A0A9J7GB49-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G6Q3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6Q3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766382", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766382", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49" } ], "pmid": "" }, { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49" } ], "pmid": "" }, { "name": "regulation of cytoskeleton organization", "id": "GO:0051493", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051493", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB49", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GB49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB49" }, { "id": "PS50021", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50021" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calponin-homology (CH)", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 112, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 28, "end_pos": 30 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GB42-1", "uniprot_ac": "A0A9J7GB42", "uniprot_id": "A0A9J7GB42_CRIGR", "mass": { "chemical_mass": 65509.0, "monoisotopic_mass": 65509.0 }, "refseq": { "ac": "XP_027279556", "name": "ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279556" }, "gene_names": [ { "name": "Ralgps1", "type": "recommended", "evidence": [ { "id": "A0A9J7GB42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42" } ] }, { "name": "Ralgps1", "type": "synonym", "evidence": [ { "id": "XP_027279556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279556" } ] } ], "protein_names": [ { "name": "Ras-specific guanine nucleotide-releasing factor RalGPS1", "type": "recommended", "evidence": [ { "id": "A0A9J7GB42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42/entry#names_and_taxonomy" } ] }, { "name": "Ral GEF with PH domain and SH3-binding motif 1", "type": "synonym", "evidence": [ { "id": "A0A9J7GB42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42/entry#names_and_taxonomy" } ] }, { "name": "Ral guanine nucleotide exchange factor 2", "type": "synonym", "evidence": [ { "id": "A0A9J7GB42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42/entry#names_and_taxonomy" } ] }, { "name": "RalA exchange factor RalGPS1", "type": "synonym", "evidence": [ { "id": "A0A9J7GB42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42/entry#names_and_taxonomy" } ] }, { "name": "ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027279556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279556" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279556", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279556" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB42", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ralgps1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42", "locus": {} } ], "crossref": [ { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13310", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13310", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762540", "url": "https://www.ncbi.nlm.nih.gov/gene/100762540", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762540", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762540", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GB42", "url": "https://www.orthodb.org/?gene=A0A9J7GB42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23113:SF167", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23113:SF167", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00617", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00617", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279556", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279556", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G8Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G8Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9C0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB42", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB42-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDR3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDR3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITLMDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKRTRDYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKEDLAGPSAGSSSARFRRRPTCPDASVAGSLPTPPVPRHRKSHSLGNNMMCQLSVVESKSATFPSEKARHLLDDSVLESRSPRRGLTLTSSTAITNGLSLGSSESSEFSEEMSAGLESRGRLYATLGPNWRVPVRNSPRTRSCVYSPTSPCNCTVGSSATVPTMEGPLRRKTLLKEGRKPALSSWTRYWVVLSGSTLLYYGAKSLRGTDRKHYKSTPGKKVSILGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNRPQVPANLMSFE", "length": 585, "header": "tr|A0A9J7GB42-1|A0A9J7GB42_CRIGR Isoform 1 of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Cricetulus griseus OX=10029 GN=Ralgps1 PE=4 SV=1 CANONICAL=A0A9J7GB42-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G8Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42/entry#A0A9J7G8Y8-1", "sequence": { "sequence": "MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITLMDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKRTRDYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKEDLAGPSAGSSSARFRRRPTCPDASVAGSLPTPPVPRHRKSHSLGNNRGRLYATLGPNWRVPVRNSPRTRSCVYSPTSPCNCTVGSSATVPTMEGPLRRKTLLKEGRKPALSSWTRYWVVLSGSTLLYYGAKSLRGTDRKHYKSTPGKKVSILGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNRPQVPANLMSFE", "length": 515, "header": "tr|A0A9J7G8Y8-1|A0A9J7GB42_CRIGR Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Cricetulus griseus OX=10029 GN=Ralgps1 PE=4 SV=1 CANONICAL=A0A9J7GB42-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G9C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42/entry#A0A9J7G9C0-1", "sequence": { "sequence": "MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITLMDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKRTRDYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKEDLADPGPRGTR", "length": 311, "header": "tr|A0A9J7G9C0-1|A0A9J7G9C0_CRIGR Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X6 OS=Cricetulus griseus OX=10029 GN=Ralgps1 PE=4 SV=1 CANONICAL=A0A9J7GB42-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB42-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42/entry#A0A9J7GB42-1", "sequence": { "sequence": "MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITLMDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKRTRDYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKEDLAGPSAGSSSARFRRRPTCPDASVAGSLPTPPVPRHRKSHSLGNNMMCQLSVVESKSATFPSEKARHLLDDSVLESRSPRRGLTLTSSTAITNGLSLGSSESSEFSEEMSAGLESRGRLYATLGPNWRVPVRNSPRTRSCVYSPTSPCNCTVGSSATVPTMEGPLRRKTLLKEGRKPALSSWTRYWVVLSGSTLLYYGAKSLRGTDRKHYKSTPGKKVSILGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNRPQVPANLMSFE", "length": 585, "header": "tr|A0A9J7GB42-1|A0A9J7GB42_CRIGR Isoform 1 of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Cricetulus griseus OX=10029 GN=Ralgps1 PE=4 SV=1 CANONICAL=A0A9J7GB42-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42/entry#A0A9J7GB47-1", "sequence": { "sequence": "MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITLMDIPVFKAIQPEVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKRTRDYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKEDLAGPSAGSSSARFRRRPTCPDASVAGSLPTPPVPRHRKSHSLGNNMMCQLSVVESKSATFPSEKARHLLDDSVLESRSPRRGLTLTSSTAITNGLSLGSSESSEFSEEMSAGLESRGRLYATLGPNWRVPVRNSPRTRSCVYSPTSPCNCTVGSSATVPTMEGPLRRKTLLKEGRKPALSSWTRYWVVLSGSTLLYYGAKSLRGTDRKHYKSTPGKKVSILGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNRPQVPANLMSFE", "length": 557, "header": "tr|A0A9J7GB47-1|A0A9J7GB47_CRIGR Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ralgps1 PE=4 SV=1 CANONICAL=A0A9J7GB42-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42/entry#A0A9J7GDR3-1", "sequence": { "sequence": "MYKRNGLMASVLVTSATPQGSSSSDSLEGQSCDYASKSYDAVVFDVLKVTPEEFASQITLMDIPVFKAIQPEELASCGWSKKEKHSLAPNVVAFTRRFNQVSFWVVREILTAQTLKIRAEILSHFVKIAKKLLELNNLHSLMSVVSALQSAPIFRLTKTWALLNRKDKTTFEKLDYLMSKEDNYKRTRDYIRSLKMVPSIPYLGIYLLDLIYIDSAYPASGSIMENEQRSNQMNNILRIIADLQVSCSYDHLTTLPHVQKYLKSVRYIEELQKFVEDDNYKLSLRIEPGSSSPRLVSSKEDLAGPSAGSSSARFRRRPTCPDASVAGSLPTPPVPRHRKSHSLGNKGRLYATLGPNWRVPVRNSPRTRSCVYSPTSPCNCTVGSSATVPTMEGPLRRKTLLKEGRKPALSSWTRYWVVLSGSTLLYYGAKSLRGTDRKHYKSTPGKKVSILGWMVQLPDDPEHPDIFQLNNPDKGNVYKFQTGSRFHAILWHKHLDDACKSNRPQVPANLMSFE", "length": 514, "header": "tr|A0A9J7GDR3-1|A0A9J7GDR3_CRIGR Computationally mapped isoform of Ras-specific guanine nucleotide-releasing factor RalGPS1 OS=Cricetulus griseus OX=10029 GN=Ralgps1 PE=4 SV=1 CANONICAL=A0A9J7GB42-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Y8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G8Y8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8Y8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762540", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762540", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB42", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB42", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Ras protein signal transduction", "id": "GO:0007265", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007265", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB42", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB42", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GB42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 459, "end_pos": 571, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7GB42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB42" }, { "id": "PS50009", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50009" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GEF", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 289, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 331 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 450, "end_pos": 452 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDS4-1", "uniprot_ac": "A0A9J7GDS4", "uniprot_id": "A0A9J7GDS4_CRIGR", "mass": { "chemical_mass": 23290.0, "monoisotopic_mass": 23290.0 }, "refseq": { "ac": "XP_027279580", "name": "probable peptidyl-tRNA hydrolase isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279580" }, "gene_names": [ { "name": "Ptrh1", "type": "recommended", "evidence": [ { "id": "A0A9J7GDS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4" } ] }, { "name": "Ptrh1", "type": "synonym", "evidence": [ { "id": "XP_027279580", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279580" } ] } ], "protein_names": [ { "name": "peptidyl-tRNA hydrolase", "type": "recommended", "evidence": [ { "id": "A0A9J7GDS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4/entry#names_and_taxonomy" } ] }, { "name": "3.1.1.29", "type": "synonym", "evidence": [ { "id": "A0A9J7GDS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4/entry#names_and_taxonomy" } ] }, { "name": "probable peptidyl-tRNA hydrolase isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027279580", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279580" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279580", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279580" } ] }, { "annotation": "Peptidyl-tRNA hydrolase that cleaves nascent chains-tRNAs that are not stably fixed in the P-site of 60S ribosome-nascent chain complexes. Acts downstream of the ribosome-associated quality control (RQC) pathway to release non-ubiquitinated nascent chains from 60S and 80S ribosome-nascent chain complexes. Does not act on ubiquitinated nascent chains, which are cleaved by ANKZF1 for degradation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4#function" }, { "database": "UniProtKB", "id": "ARBA00053438", "url": "https://www.uniprot.org/uniprotkb/ARBA00053438#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptrh1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4", "locus": {} } ], "crossref": [ { "id": "A0A9J7GDS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GDS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00462", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00462", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760505", "url": "https://www.ncbi.nlm.nih.gov/gene/100760505", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760505", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760505", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDS4", "url": "https://www.orthodb.org/?gene=A0A9J7GDS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17224", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17224", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17224:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17224:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01195", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01195", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279580", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279580", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "54448", "url": "https://www.rhea-db.org/rhea/54448", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9C8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRSGLFRSGMRRSWALRQRVSEARSPGKRWLVAGLGNHGMPGTRHSVGMAVLGQIARRLGVAESWARDPRCAADLALAPLGDAQLVLLRPRRLMNVNGRSVAQAAKLFGLTAEEIYLVHDELDKPLGKLSLKLGGSARGHNGVRSCICCLNSSAMPRLRVGIGRPTNPSMVPDYVLGYFSPEEQELLSPLLDQATDLLLDHIRARSQEPPSGL", "length": 214, "header": "tr|A0A9J7GDS4-1|A0A9J7GDS4_CRIGR Isoform 1 of peptidyl-tRNA hydrolase OS=Cricetulus griseus OX=10029 GN=Ptrh1 PE=3 SV=1 CANONICAL=A0A9J7GDS4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G9C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4/entry#A0A9J7G9C8-1", "sequence": { "sequence": "MLRSGLFRSGMRRSWALRQRVSEARSPGKRWLVAGLGNHGMPGTRHSVGMAVLGQIARRLGVAESWARDPRCAADLALAPLGDAQLVLLRPRRLMNVNGRSVAQAAKLFGLTAEEIYLVHDELDKPLGKLSLKLGGSARGHNGVRSCICCLNSSAMPRLRATDLLLDHIRARSQEPPSGL", "length": 180, "header": "tr|A0A9J7G9C8-1|A0A9J7G9C8_CRIGR Computationally mapped isoform of peptidyl-tRNA hydrolase OS=Cricetulus griseus OX=10029 GN=Ptrh1 PE=3 SV=1 CANONICAL=A0A9J7GDS4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4/entry#A0A9J7GDS4-1", "sequence": { "sequence": "MLRSGLFRSGMRRSWALRQRVSEARSPGKRWLVAGLGNHGMPGTRHSVGMAVLGQIARRLGVAESWARDPRCAADLALAPLGDAQLVLLRPRRLMNVNGRSVAQAAKLFGLTAEEIYLVHDELDKPLGKLSLKLGGSARGHNGVRSCICCLNSSAMPRLRVGIGRPTNPSMVPDYVLGYFSPEEQELLSPLLDQATDLLLDHIRARSQEPPSGL", "length": 214, "header": "tr|A0A9J7GDS4-1|A0A9J7GDS4_CRIGR Isoform 1 of peptidyl-tRNA hydrolase OS=Cricetulus griseus OX=10029 GN=Ptrh1 PE=3 SV=1 CANONICAL=A0A9J7GDS4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4/entry#A0A9J7JTE4-1", "sequence": { "sequence": "MLRSGLFRSGMRRSWALRQRVSEARSPGKRWLVAGLGNHGMPGTRHSVGMAVLGQIARRLGVAESWARDPRCAADLALAPLGDAQLVLLRPRRLMNVNGRSVAQAAKLFGLTAEEIYLVHDELDKPLGKLSLKLGGSARQCRGYGPPTCFWTTSVLEARNHHRAYDSSGHIYLFDCLPVP", "length": 180, "header": "tr|A0A9J7JTE4-1|A0A9J7JTE4_CRIGR Computationally mapped isoform of Probable peptidyl-tRNA hydrolase isoform X4 OS=Cricetulus griseus OX=10029 GN=Ptrh1 PE=4 SV=1 CANONICAL=A0A9J7GDS4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760505", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760505", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptidyl-tRNA hydrolase activity", "id": "GO:0004045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004045", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4" } ], "pmid": "" }, { "name": "tRNA binding", "id": "GO:0000049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000049", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "54448", "name": "", "equation": "an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GXN8-1", "A0A9J7GBP1-1", "A0A9J7GDS4-1" ], "evidence": [ { "id": "54448", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/54448" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7GBP1", "gene_name": "Ptrh2", "activity": [ { "ec_number": "3.1.1.29", "activity": "an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+).", "evidence": [ { "id": "A0A9J7GBP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP1" } ] }, { "ec_number": "3.1.1.29", "activity": "", "evidence": [ { "id": "A0A9J7GBP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP1" } ] } ] }, { "uniprot_ac": "A0A9J7GDS4", "gene_name": "Ptrh1", "activity": [ { "ec_number": "3.1.1.29", "activity": "an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+).", "evidence": [ { "id": "A0A9J7GDS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4" } ] }, { "ec_number": "3.1.1.29", "activity": "", "evidence": [ { "id": "A0A9J7GDS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDS4" } ] } ] }, { "uniprot_ac": "G3GXN8", "gene_name": "Ptrhd1", "activity": [ { "ec_number": "3.1.1.29", "activity": "an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+).", "evidence": [ { "id": "G3GXN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXN8" } ] }, { "ec_number": "3.1.1.29", "activity": "", "evidence": [ { "id": "G3GXN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GXN8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.1.29", "ec_name": "an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+).", "evidence": [ { "id": "3.1.1.29", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.1.29" }, { "id": "3.1.1.29", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.1.29" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GC14-1", "uniprot_ac": "A0A9J7GC14", "uniprot_id": "A0A9J7GC14_CRIGR", "mass": { "chemical_mass": 64744.0, "monoisotopic_mass": 64744.0 }, "refseq": { "ac": "XP_007649580", "name": "zinc finger protein 512 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649580" }, "gene_names": [ { "name": "Znf512", "type": "recommended", "evidence": [ { "id": "A0A9J7GC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14" } ] }, { "name": "Znf512", "type": "synonym", "evidence": [ { "id": "XP_007649580", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649580" } ] } ], "protein_names": [ { "name": "Zinc finger protein 512", "type": "recommended", "evidence": [ { "id": "A0A9J7GC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 512 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007649580", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649580" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613628.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007649580", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649580" } ] }, { "annotation": "Sequence-specific DNA-binding protein that recognizes repetitive and non-consecutive TTC sequences in pericentric repeat and initiates heterochromatin formation through interaction with SUV39H1/2 methyltransferases which catalyze histone H3K9 methylation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9R8#function" }, { "database": "UniProtKB", "id": "ARBA00094148", "url": "https://www.uniprot.org/uniprotkb/ARBA00094148#function" }, { "database": "UniProtKB", "id": "A0A9J7GC14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14#function" }, { "database": "UniProtKB", "id": "A0A9J7GC18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC18#function" }, { "database": "UniProtKB", "id": "A0A9J7JTU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTU9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf512", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14", "locus": {} } ], "crossref": [ { "id": "A0A9J7GC14", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GC14", "database": "AlphaFoldDB", "categories": [] }, { "id": "100762981", "url": "https://www.ncbi.nlm.nih.gov/gene/100762981", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052274", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052274", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762981", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762981", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7G9R8", "url": "https://www.orthodb.org/?gene=A0A9J7G9R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GC14", "url": "https://www.orthodb.org/?gene=A0A9J7GC14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GC18", "url": "https://www.orthodb.org/?gene=A0A9J7GC18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JTU9", "url": "https://www.orthodb.org/?gene=A0A9J7JTU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22979", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22979", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22979:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22979:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21276", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21276", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21367", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21367", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007649580", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649580", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G9R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G9R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC14-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC18", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC18-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTU9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSRLGAVTATPGPTPFKQQRSTRIVGAKNSRTQCSIKDNSFQYTIPHDDSLSGSSSASSCEPVSDFPASFRKSTYWMKMRRIKPAATSQVEDAGAKEKEKEKAKGKRKIKQEEDEDYRELPQKKHKLYGRKQRPKAQPHPKPQARRVRKEPPVYAAGSMEEKWYLEIMDKGSVSCPTCQAVGRKTIEGLKKHMENCKQEMFTCHHCGKQLHSLAGMKYHVMANHNSLPILKAGDEVDEPSERERLRTVLKRMGKLRCMRESCSSTFTSIMGYLYHVRKCGKEAAELEKLTLKCHHCGKPYRSKAGLAYHMRSEHGPVFFPESGQQDCLKEMSLEAKGGGRVQRRSAKIAVYHLQELASAELTKEWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSVSGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEKLMKIKQRQQEEEKQRQQQGSRRSLRRQQQPRPEQPESQPESRAGKGQGGNEELVVSAVCKGSEQEPVPAQSQKAEPTKTTHKRGRK", "length": 570, "header": "tr|A0A9J7GC14-1|A0A9J7GC14_CRIGR Isoform 1 of Zinc finger protein 512 OS=Cricetulus griseus OX=10029 GN=Znf512 PE=3 SV=1 CANONICAL=A0A9J7GC14-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G9R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14/entry#A0A9J7G9R8-1", "sequence": { "sequence": "MSSRLGAVTATPGPTPFKQQRSTRIVGAKNSRTQCSIKDNSFQYTIPHDDSLSGSSSASSCEPVSDFPASFRKSTYWMKMRRIKPAATSQVEGAKEKEKEKAKGKRKIKQEEDEDYRELPQKKHKLYGRKQRPKAQPHPKPQARRVRKEPPVYAAGSMEEKWYLEIMDKGSVSCPTCQAVGRKTIEGLKKHMENCKQEMFTCHHCGKQLHSLAGMKYHVMANHNSLPILKAGDEVDEPSERERLRTVLKRMGKLRCMRESCSSTFTSIMGYLYHVRKCGKEAAELEKLTLKCHHCGKPYRSKAGLAYHMRSEHGPVFFPESGQQDCLKEMSLEAKGGGRVQRRSAKIAVYHLQELASAELTKEWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSVSGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEKLMKIKQRQQEEEKQRQQQGSRRSLRRQQQPRPEQPESQPESRAGKGQGGNEELVVSAVCKGSEQEPVPAQSQKAEPTKTTHKRGRK", "length": 568, "header": "tr|A0A9J7G9R8-1|A0A9J7GC14_CRIGR Computationally mapped isoform of Zinc finger protein 512 OS=Cricetulus griseus OX=10029 GN=Znf512 PE=3 SV=1 CANONICAL=A0A9J7GC14-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GC14-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14/entry#A0A9J7GC14-1", "sequence": { "sequence": "MSSRLGAVTATPGPTPFKQQRSTRIVGAKNSRTQCSIKDNSFQYTIPHDDSLSGSSSASSCEPVSDFPASFRKSTYWMKMRRIKPAATSQVEDAGAKEKEKEKAKGKRKIKQEEDEDYRELPQKKHKLYGRKQRPKAQPHPKPQARRVRKEPPVYAAGSMEEKWYLEIMDKGSVSCPTCQAVGRKTIEGLKKHMENCKQEMFTCHHCGKQLHSLAGMKYHVMANHNSLPILKAGDEVDEPSERERLRTVLKRMGKLRCMRESCSSTFTSIMGYLYHVRKCGKEAAELEKLTLKCHHCGKPYRSKAGLAYHMRSEHGPVFFPESGQQDCLKEMSLEAKGGGRVQRRSAKIAVYHLQELASAELTKEWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSVSGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEKLMKIKQRQQEEEKQRQQQGSRRSLRRQQQPRPEQPESQPESRAGKGQGGNEELVVSAVCKGSEQEPVPAQSQKAEPTKTTHKRGRK", "length": 570, "header": "tr|A0A9J7GC14-1|A0A9J7GC14_CRIGR Isoform 1 of Zinc finger protein 512 OS=Cricetulus griseus OX=10029 GN=Znf512 PE=3 SV=1 CANONICAL=A0A9J7GC14-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GC18-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14/entry#A0A9J7GC18-1", "sequence": { "sequence": "MSSRLGAVTATPGPTPFKQQRSTRIVGAKNRTQCSIKDNSFQYTIPHDDSLSGSSSASSCEPVSDFPASFRKSTYWMKMRRIKPAATSQVEDAGAKEKEKEKAKGKRKIKQEEDEDYRELPQKKHKLYGRKQRPKAQPHPKPQARRVRKEPPVYAAGSMEEKWYLEIMDKGSVSCPTCQAVGRKTIEGLKKHMENCKQEMFTCHHCGKQLHSLAGMKYHVMANHNSLPILKAGDEVDEPSERERLRTVLKRMGKLRCMRESCSSTFTSIMGYLYHVRKCGKEAAELEKLTLKCHHCGKPYRSKAGLAYHMRSEHGPVFFPESGQQDCLKEMSLEAKGGGRVQRRSAKIAVYHLQELASAELTKEWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSVSGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEKLMKIKQRQQEEEKQRQQQGSRRSLRRQQQPRPEQPESQPESRAGKGQGGNEELVVSAVCKGSEQEPVPAQSQKAEPTKTTHKRGRK", "length": 569, "header": "tr|A0A9J7GC18-1|A0A9J7GC18_CRIGR Computationally mapped isoform of Zinc finger protein 512 OS=Cricetulus griseus OX=10029 GN=Znf512 PE=3 SV=1 CANONICAL=A0A9J7GC14-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14/entry#A0A9J7JTU9-1", "sequence": { "sequence": "MKMRRIKPAATSQVEDAGAKEKEKEKAKGKRKIKQEEDEDYRELPQKKHKLYGRKQRPKAQPHPKPQARRVRKEPPVYAAGSMEEKWYLEIMDKGSVSCPTCQAVGRKTIEGLKKHMENCKQEMFTCHHCGKQLHSLAGMKYHVMANHNSLPILKAGDEVDEPSERERLRTVLKRMGKLRCMRESCSSTFTSIMGYLYHVRKCGKEAAELEKLTLKCHHCGKPYRSKAGLAYHMRSEHGPVFFPESGQQDCLKEMSLEAKGGGRVQRRSAKIAVYHLQELASAELTKEWPKRKVLQDLVPDDRKLKYTRPGLPTFSQEVLHKWKTDIKKYHRIQCPNQGCEAVYSSVSGLKAHLGSCTLGNFVAGKYKCLLCQKEFVSESGVKYHINSVHAEDWFVVNPTTTKSFEKLMKIKQRQQEEEKQRQQQGSRRSLRRQQQPRPEQPESQPESRAGKGQGGNEELVVSAVCKGSEQEPVPAQSQKAEPTKTTHKRGRK", "length": 493, "header": "tr|A0A9J7JTU9-1|A0A9J7JTU9_CRIGR Computationally mapped isoform of Zinc finger protein 512 OS=Cricetulus griseus OX=10029 GN=Znf512 PE=3 SV=1 CANONICAL=A0A9J7GC14-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 11, "start_aa": "Thr", "end_pos": 11, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr11", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 15, "start_aa": "Thr", "end_pos": 15, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr15", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9R8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7G9R8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9R8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762981", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762981", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC14" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 292, "end_pos": 315, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 11, 15 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GCG8-1", "uniprot_ac": "A0A9J7GCG8", "uniprot_id": "A0A9J7GCG8_CRIGR", "mass": { "chemical_mass": 68517.0, "monoisotopic_mass": 68517.0 }, "refseq": { "ac": "XP_027280574", "name": "eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280574" }, "gene_names": [ { "name": "Gspt1", "type": "recommended", "evidence": [ { "id": "A0A9J7GCG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8" } ] }, { "name": "Gspt1", "type": "synonym", "evidence": [ { "id": "XP_027280574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280574" } ] } ], "protein_names": [ { "name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7GCG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8/entry#names_and_taxonomy" } ] }, { "name": "eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027280574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280574" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280574" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCG8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gspt1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCG8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCG8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01883", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01883", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03704", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03704", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04089", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04089", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753280", "url": "https://www.ncbi.nlm.nih.gov/gene/100753280", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050100", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050100", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753280", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753280", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCG8", "url": "https://www.orthodb.org/?gene=A0A9J7GCG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00009", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00009", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03144", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03144", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22594", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22594", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19669", "url": "https://www.rhea-db.org/rhea/19669", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GA57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GA57-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAN9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCG8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GF61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GF61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF61-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPGSGGGGGGGGGGSSSSSDSAPDCWDQTDMEAPGPGPCGGGSMAGMAEAQRENLSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAQPPPSPAGAAGGDHGASSSAGGPPAPVESSQEQSLLCEGSNSAVSMELSEPVVENGETEMSPEESWEHKEEISEAEPGGGSSGDGRPPEENTQEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDSVAPGENLKIRLKGIEEEEILPGFILCDLTNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 633, "header": "tr|A0A9J7GCG8-1|A0A9J7GCG8_CRIGR Isoform 1 of Eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X3 OS=Cricetulus griseus OX=10029 GN=Gspt1 PE=3 SV=1 CANONICAL=A0A9J7GCG8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GA57-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8/entry#A0A9J7GA57-1", "sequence": { "sequence": "MDPGSGGGGGGGGGGSSSSSDSAPDCWDQTDMEAPGPGPCGGGSMAGMAEAQRENLSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAQPPPSPAGAAGGDHGASSSAGGPPAPVESSQEQSLLCEGSNSAVSMELSEPVENGETEMSPEESWEHKEEISEAEPGGGSSGDGRPPEENTQEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDSVAPGENLKIRLKGIEEEEILPGFILCDLTNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 632, "header": "tr|A0A9J7GA57-1|A0A9J7GCG8_CRIGR Computationally mapped isoform of Eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X3 OS=Cricetulus griseus OX=10029 GN=Gspt1 PE=3 SV=1 CANONICAL=A0A9J7GCG8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8/entry#A0A9J7GAN9-1", "sequence": { "sequence": "MDPGSGGGGGGGGGGSSSSSDSAPDCWDQTDMEAPGPGPCGGGSMAGMAEAQRENLSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAQPPPSPAGAAGGDHGASSSAGGPPGSNSAVSMELSEPVENGETEMSPEESWEHKEEISEAEPGGGSSGDGRPPEENTQEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDSVAPGENLKIRLKGIEEEEILPGFILCDLTNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 618, "header": "tr|A0A9J7GAN9-1|A0A9J7GCG8_CRIGR Computationally mapped isoform of Eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X3 OS=Cricetulus griseus OX=10029 GN=Gspt1 PE=3 SV=1 CANONICAL=A0A9J7GCG8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCG8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8/entry#A0A9J7GCG8-1", "sequence": { "sequence": "MDPGSGGGGGGGGGGSSSSSDSAPDCWDQTDMEAPGPGPCGGGSMAGMAEAQRENLSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAQPPPSPAGAAGGDHGASSSAGGPPAPVESSQEQSLLCEGSNSAVSMELSEPVVENGETEMSPEESWEHKEEISEAEPGGGSSGDGRPPEENTQEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDSVAPGENLKIRLKGIEEEEILPGFILCDLTNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 633, "header": "tr|A0A9J7GCG8-1|A0A9J7GCG8_CRIGR Isoform 1 of Eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X3 OS=Cricetulus griseus OX=10029 GN=Gspt1 PE=3 SV=1 CANONICAL=A0A9J7GCG8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GF61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8/entry#A0A9J7GF61-1", "sequence": { "sequence": "MDPGSGGGGGGGGGGSSSSSDSAPDCWDQTDMEAPGPGPCGGGSMAGMAEAQRENLSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAQPPPSPAGAAGGDHGASSSAGGPPGSNSAVSMELSEPVVENGETEMSPEESWEHKEEISEAEPGGGSSGDGRPPEENTQEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNRSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDSVAPGENLKIRLKGIEEEEILPGFILCDLTNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 619, "header": "tr|A0A9J7GF61-1|A0A9J7GF61_CRIGR Computationally mapped isoform of Eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X5 OS=Cricetulus griseus OX=10029 GN=Gspt1 PE=3 SV=1 CANONICAL=A0A9J7GCG8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA57" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GA57", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GA57" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753280", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753280", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCG8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCG8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8" } ], "pmid": "" }, { "name": "translation release factor activity", "id": "GO:0003747", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003747", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCG8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCG8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCG8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", "A0A8C2M6H7-1", "A0A8C2M9W6-1", "A0A9J7H2L4-1", "A0A8C2MH13-1", "A0A8C2MMV7-1", "A0A8C2MPE2-1", "A0A8C2LL65-1", "A0A3L7HXE9-1", "A0A8C2LGZ8-1", "A0A8C2LIB5-1", "A0A8C2LNU7-1", "A0A9J7JYH7-1", "A0A8C2LV21-1", "A0A9J7GDV9-1", "A0A8C2QEY0-1", "A0A9J7FVQ6-1", "A0A9J7K0X9-1", "A0A9J7J7P8-1", "A0A8C2M2X0-1", "A0A8C2MAV7-1", "A0A8C2MQL3-1", "A0A3L7HA69-1", "A0A8C2LLE7-1", "A0A061HWM0-1", "A0A061I5K5-1", "A0A061IH58-1", "A0A061INW8-1", "A0A3L7GXQ2-1", "A0A9J7GN19-1", "A0A3L7HQ44-1", "A0A3L7IA35-1", "A0A3L7IMK5-1", "A0A8C2LIE2-1", "A0A9J7GAZ9-1", "A0A9J7HCG9-1", "A0A9J7HC46-1", "A0A9J7HC79-1", "A0A9J7HCE0-1", "A0A9J7JRE1-1", "A0A9J7GJ78-1", "A0A9J7GKH5-1", "A0A9J7GL76-1", "A0A9J7GLC6-1", "A0A9J7GRC9-1", "A0A9J7GM12-1", "A0A9J7GM74-1", "A0A9J7GP64-1", "A0A9J7GPV5-1", "A0A9J7GQI1-1", "A0A9J7GR82-1", "A0A9J7JY44-1", "A0A9J7JTP9-1", "A0A9J7HGR2-1", "A0A9J7JZZ6-1", "A0A9J7K3I9-1", "A0A9J7K4X6-1", "A0A9J7HD72-1", "A0A9J7KEX2-1", "A0A9J7KFX8-1", "A0A9J7KEY0-1", "A0A9J7KF02-1", "A0A9J7KF14-1", "A0A9J7HFH8-1", "A0A9J7HEY0-1", "A0A9J7KG38-1", "A0A9J7HCJ6-1", "A0A9J7HCM3-1", "A0A9J7HCS9-1", "A0A9J7HD53-1", "A0A9J7HD81-1", "A0A9J7HFN4-1", "A0A9J7HCM7-1", "A0A9J7HCP3-1", "A0A9J7HD44-1", "A0A9J7HFL5-1", "A0A9J7HEX1-1", "A0A9J7HF32-1", "A0A9J7HFQ3-1", "A0A9J7GPD5-1", "A0A9J7HGT1-1", "A0A9J7HH79-1", "A0A9J7GR00-1", "P09445-1", "P62629-1", "P68361-1", "P68362-1", "P68365-1", "Q9QVY3-1", "A0A9J7F4Q2-1", "A0A9J7H7U2-1", "G3GW97-1", "A0A9J7K418-1", "A0A8C2QEV4-1", "A0A9J7FCD6-1", "A0A9J7JMD0-1", "A0A9J7K9Z1-1", "A0A9J7K3M9-1", "A0A8C2ME21-1", "A0A061I233-1", "A0A3L7H955-1", "A0A8C2MJ36-1", "A0A9J7FDQ9-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HWM0", "gene_name": "LOC113837706", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061HWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HWM0" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061HWM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HWM0" } ] } ] }, { "uniprot_ac": "A0A061HZZ7", "gene_name": "Rab9b", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061HZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZZ7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061HZZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZZ7" } ] } ] }, { "uniprot_ac": "A0A061I233", "gene_name": "Rabl3", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061I233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I233" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061I233", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I233" } ] } ] }, { "uniprot_ac": "A0A061I5F7", "gene_name": "Rac1", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061I5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5F7" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061I5F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5F7" } ] } ] }, { "uniprot_ac": "A0A061I5K5", "gene_name": "Rasl11a", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061I5K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5K5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061I5K5", 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GB15-1", "uniprot_ac": "A0A9J7GB15", "uniprot_id": "A0A9J7GB15_CRIGR", "mass": { "chemical_mass": 66962.0, "monoisotopic_mass": 66962.0 }, "refseq": { "ac": "XP_007641147", "name": "metal-response element-binding transcription factor 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641147" }, "gene_names": [ { "name": "Mtf2", "type": "recommended", "evidence": [ { "id": "A0A9J7GB15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ] }, { "name": "Mtf2", "type": "synonym", "evidence": [ { "id": "XP_007641147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641147" } ] } ], "protein_names": [ { "name": "Metal-response element-binding transcription factor 2", "type": "recommended", "evidence": [ { "id": "A0A9J7GB15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15/entry#names_and_taxonomy" } ] }, { "name": "Metal regulatory transcription factor 2", "type": "synonym", "evidence": [ { "id": "A0A9J7GB15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15/entry#names_and_taxonomy" } ] }, { "name": "metal-response element-binding transcription factor 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007641147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641147" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613892.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007641147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641147" } ] }, { "annotation": "Polycomb group (PcG) protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally. Binds to the metal-regulating-element (MRE) of MT1A gene promoter.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15#function" }, { "database": "UniProtKB", "id": "ARBA00058935", "url": "https://www.uniprot.org/uniprotkb/ARBA00058935#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mtf2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15", "locus": {} } ], "crossref": [ { "id": "A0A9J7GB15", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GB15", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15578", "url": 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"categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764652", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764652", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GB15", "url": "https://www.orthodb.org/?gene=A0A9J7GB15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GFQ5", "url": "https://www.orthodb.org/?gene=A0A9J7GFQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12628:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12628:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18104", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18104", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007641147", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641147", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB15-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GFQ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GFQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRDSTGAGNSLVHKRSPLRRNQKTPASLNKLSLQDGHKAKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPLSDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLGKESVSENPALDLPCSIGRTEGIAHSSNTSDVDLTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRTLQTQNSEVVKDDEGKEDYQFEEINTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 593, "header": "tr|A0A9J7GB15-1|A0A9J7GB15_CRIGR Isoform 1 of Metal-response element-binding transcription factor 2 OS=Cricetulus griseus OX=10029 GN=Mtf2 PE=3 SV=1 CANONICAL=A0A9J7GB15-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GB15-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15/entry#A0A9J7GB15-1", "sequence": { "sequence": "MRDSTGAGNSLVHKRSPLRRNQKTPASLNKLSLQDGHKAKKPACKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDIQTGATGSGEMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPLSDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLGKESVSENPALDLPCSIGRTEGIAHSSNTSDVDLTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRTLQTQNSEVVKDDEGKEDYQFEEINTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 593, "header": "tr|A0A9J7GB15-1|A0A9J7GB15_CRIGR Isoform 1 of Metal-response element-binding transcription factor 2 OS=Cricetulus griseus OX=10029 GN=Mtf2 PE=3 SV=1 CANONICAL=A0A9J7GB15-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GFQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15/entry#A0A9J7GFQ5-1", "sequence": { "sequence": "MVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDSSVIDSDEKWLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTNVQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFICSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINENWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRIRVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPLSDSREVSNGIEKKGKKKSVGRPPGPYTRKMIQKTAEPPLGKESVSENPALDLPCSIGRTEGIAHSSNTSDVDLTGASSAKETTSSSISRHYGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRTLQTQNSEVVKDDEGKEDYQFEEINTEILNNLADQELQLNHLKNSITSYFGAAGRIACGEKYRVLARRVTLDGKVQYLVEWEGATAS", "length": 491, "header": "tr|A0A9J7GFQ5-1|A0A9J7GFQ5_CRIGR Computationally mapped isoform of Metal-response element-binding transcription factor 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mtf2 PE=4 SV=1 CANONICAL=A0A9J7GB15-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764652", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764652", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "stem cell differentiation", "id": "GO:0048863", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048863", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ], "pmid": "" }, { "name": "stem cell population maintenance", "id": "GO:0019827", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ], "pmid": "" }, { "name": "negative regulation of gene expression, epigenetic", "id": "GO:0045814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GB15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB15" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 102, "end_pos": 157, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 }, { "start_pos": 450, "end_pos": 452 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GB34-1", "uniprot_ac": "A0A9J7GB34", "uniprot_id": "A0A9J7GB34_CRIGR", "mass": { "chemical_mass": 205237.0, "monoisotopic_mass": 205237.0 }, "refseq": { "ac": "XP_027280895", "name": "WD repeat-containing protein 90 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280895" }, "gene_names": [ { "name": "Wdr90", "type": "recommended", "evidence": [ { "id": "A0A9J7GB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34" } ] }, { "name": "Wdr90", "type": "synonym", "evidence": [ { "id": "XP_027280895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280895" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 90", "type": "recommended", "evidence": [ { "id": "A0A9J7GB34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 90 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_027280895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280895" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280895" } ] }, { "annotation": "Microtubule-binding protein that plays a crucial role in ensuring inner core protein localization within the centriole core, as well as in maintaining the microtubule wall integrity and the overall centriole roundness and stability. Required for efficient primary cilium formation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34#function" }, { "database": "UniProtKB", "id": "ARBA00060089", "url": "https://www.uniprot.org/uniprotkb/ARBA00060089#function" }, { "database": "UniProtKB", "id": "A0A9J7JU95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU95#function" }, { "database": "UniProtKB", "id": "A0A9J7KA72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KA72#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wdr90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34", "locus": {} } ], "crossref": [ { "id": "100760189", "url": "https://www.ncbi.nlm.nih.gov/gene/100760189", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760189", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760189", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GB34", "url": "https://www.orthodb.org/?gene=A0A9J7GB34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13720:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13720:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23342", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23342", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23393", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23393", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280895", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GB34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB34-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB41-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JU95", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JU95-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KA72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KA72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KA72-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KA72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRVLRRTASAEAGSASCSAMAGGSCARLERCGRVSRPGSTGSEVPPASLTVPRAETCPARGGGGSRRSAQDRCSGGVPSPASWQLPFLNVFRHFRVDEWKRSSKEGDVALVTDKVLKSSVYRIRGSVSASNYIQLPRTSTQSLGLTGRYLYVLFRPLPTKHFVIHLDVSTEDGQVIRVSFSNLFKEFKSSATWLQFPFVFETKTPRRDLAGVAPPNARWTCLQLDLRDILIFYLSRHYGHLKSIRLCANLLVRNLYTSDLCFDPAVTVTEARRVKLPVSPVPREMAFPVPKGERWHDHYIHVRFPSYGSRAPSEHVEKSCNPPETGHVSQRPPHPAVFGKPLLSNRSSAAQISSPVLPCKVPSAPRLLPEVSLTYQHPEVSSIGATSIPGQHPSAWVEATDAHTVVSGRRALADKSSGVPVALEDLGSCKLFLPDPVLRLKGIIGFGGHSTQWALWTKDGMAVVYPCHAVIIILRVDTRQQRFFLGHTDKVSALALDRNDALLASAQVQPPSMVRLWDFQTGACLSLFRSPLHTVCSLSFSGSGALLCGVGKDRHGRTVVVAWGTDQVGLGGEVVVLAKVHTDFDIQAFRIAFFDETRMASCGRGSVRLWRLRGGALRSCAVDLGEYCALELTDLAFAQALDGHQASLAGILFVCSHSGHILEIDHQRMAVRHIRRLLPTQSPGVPLTEKQSFSVGSGIAISSLGVSTTTCAVGSEDGYLRLWPLDFSSVLLEAEHDGPVSSVSFSPDGMRVLSTTTSGHLGFLDIPSREYTVLTRSHMAPVLALSTEQNRGQMATVSLDHTVRIWDLATLQQLYDFSSSDETPCAVAFHPTLPNFFCGFSSGAVRSFSLENSEVLVEHTRHRGTITSLVITPDGRFLFSSCSQGSLVQYNCSVSRCCVLRVAANVVCQDGRPKPNILAVSGDSCRLAIVGPSKCTVTVMESASLDELLRVDVSTLNLASNHLDWAVAVCFSPGDSSHLLVSTSSNKVVVLDAVSGHTLRKFSSVRSRACPSLALSVDARLLLAATGRTITVWDYPTQPNSSCQVYIGHSEPVRVVAFTPDQKQVLSVGDAIFLWDVLDIPESDQNESGAFSVHEPDSIAGQLEDLASGASGLPRLQVPIPSQASPPPLSIHDRPLEDSAGTFSTSDEEGLCEENHVSEALLQAQAPTPPVLVEREASGAGDGSRQAAKGSWAPAVVPYHPSQTSDWSLRRVKPGLPTRPDSYKHFTARYKASTRVKSVSFPPVGREQLRLKAVVGYNGNGRVNMVWRPDTGFFAYTCGRLVVVEDLHSGTQRHWLGHPQEISTLALNQDGQVLASASCCGNTATRCQIRIWDVSKGLCQHLLSHHDTAIQALAFSPDDEFLVTLGDYADLTLVLWSTATYELLSSTRLPEPVHGVAFNPWDANELISVGTSAITFWLLQHNGTDTSFQVHREPVPEELGASELTSLCYGASPLLYCGSSSGQVCVWDTGTSRCFLAWEADEGEIGVLLCSGSRLVSGSNTKRLRLWAVGVVPELRRKGSSARSSSVFMERELTLDGAIVSASFDSGMDMGVVGTTAGTLWYISWTEGTSTRLISGHRSKVNEVVFSPNESHCATCGEDGSVRVWSLASMELVIQFQVLNQSCLCLAWTPPSCGRPEQQQVVAGYSDGTLRVFSISRTAMELKMHPHRTALTAIAFSSDGQTILSGDKDGLVAISHPCTGMTFRVLSDHRGAPISAIQSISKEYGDLGVEGVDLWLAASGDQRVSVWASDWLRDRCELLEWLSFPAPATSEALGLLPPSLAAFCPWDRAILVCVGLGAHEEVIFYSLRQKQVVQKTPLPFFAMSLSLSPGAQLMVVGFAECMLRLLDCESGTAQDFEGHDDSVHLCRFTPSGRLLFTAAHNEILVWEVTSPSP", "length": 1893, "header": "tr|A0A9J7GB34-1|A0A9J7GB34_CRIGR Isoform 1 of WD repeat-containing protein 90 OS=Cricetulus griseus OX=10029 GN=Wdr90 PE=3 SV=1 CANONICAL=A0A9J7GB34-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GB34-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34/entry#A0A9J7GB34-1", "sequence": { "sequence": "MRVLRRTASAEAGSASCSAMAGGSCARLERCGRVSRPGSTGSEVPPASLTVPRAETCPARGGGGSRRSAQDRCSGGVPSPASWQLPFLNVFRHFRVDEWKRSSKEGDVALVTDKVLKSSVYRIRGSVSASNYIQLPRTSTQSLGLTGRYLYVLFRPLPTKHFVIHLDVSTEDGQVIRVSFSNLFKEFKSSATWLQFPFVFETKTPRRDLAGVAPPNARWTCLQLDLRDILIFYLSRHYGHLKSIRLCANLLVRNLYTSDLCFDPAVTVTEARRVKLPVSPVPREMAFPVPKGERWHDHYIHVRFPSYGSRAPSEHVEKSCNPPETGHVSQRPPHPAVFGKPLLSNRSSAAQISSPVLPCKVPSAPRLLPEVSLTYQHPEVSSIGATSIPGQHPSAWVEATDAHTVVSGRRALADKSSGVPVALEDLGSCKLFLPDPVLRLKGIIGFGGHSTQWALWTKDGMAVVYPCHAVIIILRVDTRQQRFFLGHTDKVSALALDRNDALLASAQVQPPSMVRLWDFQTGACLSLFRSPLHTVCSLSFSGSGALLCGVGKDRHGRTVVVAWGTDQVGLGGEVVVLAKVHTDFDIQAFRIAFFDETRMASCGRGSVRLWRLRGGALRSCAVDLGEYCALELTDLAFAQALDGHQASLAGILFVCSHSGHILEIDHQRMAVRHIRRLLPTQSPGVPLTEKQSFSVGSGIAISSLGVSTTTCAVGSEDGYLRLWPLDFSSVLLEAEHDGPVSSVSFSPDGMRVLSTTTSGHLGFLDIPSREYTVLTRSHMAPVLALSTEQNRGQMATVSLDHTVRIWDLATLQQLYDFSSSDETPCAVAFHPTLPNFFCGFSSGAVRSFSLENSEVLVEHTRHRGTITSLVITPDGRFLFSSCSQGSLVQYNCSVSRCCVLRVAANVVCQDGRPKPNILAVSGDSCRLAIVGPSKCTVTVMESASLDELLRVDVSTLNLASNHLDWAVAVCFSPGDSSHLLVSTSSNKVVVLDAVSGHTLRKFSSVRSRACPSLALSVDARLLLAATGRTITVWDYPTQPNSSCQVYIGHSEPVRVVAFTPDQKQVLSVGDAIFLWDVLDIPESDQNESGAFSVHEPDSIAGQLEDLASGASGLPRLQVPIPSQASPPPLSIHDRPLEDSAGTFSTSDEEGLCEENHVSEALLQAQAPTPPVLVEREASGAGDGSRQAAKGSWAPAVVPYHPSQTSDWSLRRVKPGLPTRPDSYKHFTARYKASTRVKSVSFPPVGREQLRLKAVVGYNGNGRVNMVWRPDTGFFAYTCGRLVVVEDLHSGTQRHWLGHPQEISTLALNQDGQVLASASCCGNTATRCQIRIWDVSKGLCQHLLSHHDTAIQALAFSPDDEFLVTLGDYADLTLVLWSTATYELLSSTRLPEPVHGVAFNPWDANELISVGTSAITFWLLQHNGTDTSFQVHREPVPEELGASELTSLCYGASPLLYCGSSSGQVCVWDTGTSRCFLAWEADEGEIGVLLCSGSRLVSGSNTKRLRLWAVGVVPELRRKGSSARSSSVFMERELTLDGAIVSASFDSGMDMGVVGTTAGTLWYISWTEGTSTRLISGHRSKVNEVVFSPNESHCATCGEDGSVRVWSLASMELVIQFQVLNQSCLCLAWTPPSCGRPEQQQVVAGYSDGTLRVFSISRTAMELKMHPHRTALTAIAFSSDGQTILSGDKDGLVAISHPCTGMTFRVLSDHRGAPISAIQSISKEYGDLGVEGVDLWLAASGDQRVSVWASDWLRDRCELLEWLSFPAPATSEALGLLPPSLAAFCPWDRAILVCVGLGAHEEVIFYSLRQKQVVQKTPLPFFAMSLSLSPGAQLMVVGFAECMLRLLDCESGTAQDFEGHDDSVHLCRFTPSGRLLFTAAHNEILVWEVTSPSP", "length": 1893, "header": "tr|A0A9J7GB34-1|A0A9J7GB34_CRIGR Isoform 1 of WD repeat-containing protein 90 OS=Cricetulus griseus OX=10029 GN=Wdr90 PE=3 SV=1 CANONICAL=A0A9J7GB34-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB41-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34/entry#A0A9J7GB41-1", "sequence": { "sequence": "MRVLRRTASAEAGSASCSAMAGGSCARLERCGRVSRPGSTGSEVPPASLTVPRAETCPARGGGGSRRSAQDRCSGGVPSPASWQLPFLNVFRHFRVDEWKRSSKEGDVALVTDKVLKSSVYRIRGSVSASNYIQLPRTSTQSLGLTGRYLYVLFRPLPTKHFVIHLDVSTEDGQVIRVSFSNLFKEFKSSATWLQFPFVFETKTPRRDLAGVAPPNARWTCLQLDLRDILIFYLSRHYGHLKSIRLCANLLVRNLYTSDLCFDPAVTVTEARRVKLPVSPVPREMAFPVPKGERWHDHYIHVRFPSYGSRAPSEHVEKSCNPPETGHVSQRPPHPAVFGKPLLSNRSSAAQISSPVLPCKVPSAPRLLPEVSLTYQHPEVSSIGATSIPGQHPSAWVEATDAHTVVSGRRALADKSSGVPVALEDLGSCKLFLPDPVLRLKGIIGFGGHSTQWALWTKDGMAVVYPCHAVIIILRVDTRQQRFFLGHTDKVSALALDRNDALLASAQVQPPSMVRLWDFQTGACLSLFRSPLHTVCSLSFSGSGALLCGVGKDRHGRTVVVAWGTDQVGLGGEVVVLAKVHTDFDIQAFRIAFFDETRMASCGRGSVRLWRLRGGALRSCAVDLGEYCALELTDLAFAQALDGHQASLAGILFVCSHSGHILEIDHQRMAVRHIRRLLPTQSPGVPLTEKQSFSVGSGIAISSLGVSTTTCAVGSEDGYLRLWPLDFSSVLLEAEHDGPVSSVSFSPDGMRVLSTTTSGHLGFLDIPSREYTVLTRSHMAPVLALSTEQNRGQMATVSLDHTVRIWDLATLQQLYDFSSSDETPCAVAFHPTLPNFFCGFSSGAVRSFSLENSEVLVEHTRHRGTITSLVITPDGRFLFSSCSQGSLVQYNCSVSRCCVLRVAANVVCQDGRPKPNILAVSGDSCRLAIVGPSKCTVTVMESASLDELLRVDVSTLNLASNHLDWAVAVCFSPGDSSHLLVSTSSNKVVVLDAVSGHTLRKFSSVRSRACPSLALSVDARLLLAATGRTITVWDYPTQPNSSCQVYIGHSEPVRVVAFTPDQKQVLSVGDAIFLWDVLDIPESDQNESGAFSVHEPDSIAGQLEDLASGASGLPRLQVPIPSQASPPPLSIHDRPLEDSAGTFSTSDEEGLCEENHVSEALLQAQAPTPPVLVEREASGAGDGSRQAAKGSWAPAVVPYHPSQTSDWSLRRVKPGLPTRPDSYKHFTARYKASTRVKSVSFPPVGREQLRLKAVVGYNGNGRVNMVWRPDTGFFAYTCGRLVVVEDLHSGTQRHWLGHPQEISTLALNQDGQVLASASCCGNTATRCQIRIWDVSKGLCQHLLSHHDTAIQALAFSPDDEFLVTLGDYADLTLVLWSTATYELLSSTRLPEPVHGVAFNPWDANELISVGTSAITFWLLQHNGTDTSFQVHREPVPEELGASELTSLCYGASPLLYCGSSSGQVCVWDTGTSRCFLAWEADEGEIGVLLCSGSRLVSGSNTKRLRLWAVGVVPELRRKGSSARSSSVFMERELTLDGAIVSASFDSGMDMGVVGTTAGTLWYISWTEGTSTRLISGHRSKVNEVVFSPNESHCATCGEDGSVRVWSLASMELVIQFQVLNQSCLCLAWTPPSCGRPEQQQVVAGYSDGTLRVFSISRTAMELKMHPHRTALTAIAFSSDGQTILSGDKDGLVAISHPCTGMTFRVLSDHRGAPISAIQSISKEYGDLGVEGVDLWLAASGDQRVSVWASDWLRDRCELLEWLSFPAPATSEALGLLPPSLAAFCPWDRAILVCVGLGAHEEVIFYSLRQKQVVQKTPLPFFAMSLSLSPGAQLMVVGFAAFLATGLST", "length": 1848, "header": "tr|A0A9J7GB41-1|A0A9J7GB41_CRIGR Computationally mapped isoform of WD repeat-containing protein 90 isoform X7 OS=Cricetulus griseus OX=10029 GN=Wdr90 PE=4 SV=1 CANONICAL=A0A9J7GB34-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JU95-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34/entry#A0A9J7JU95-1", "sequence": { "sequence": 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"length": 1850, "header": "tr|A0A9J7JU95-1|A0A9J7JU95_CRIGR Computationally mapped isoform of WD repeat-containing protein 90 OS=Cricetulus griseus OX=10029 GN=Wdr90 PE=3 SV=1 CANONICAL=A0A9J7GB34-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KA72-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34/entry#A0A9J7KA72-1", "sequence": { "sequence": "MAFPVPKGERWHDHYIHVRFPSYGSRAPSEHVEKSCNPPETGHVSQRPPHPAVFGKPLLSNRSSAAQISSPVLPCKVPSAPRLLPEVSLTYQHPEVSSIGATSIPGQHPSAWVEATDAHTVVSGRRALADKSSGVPVALEDLGSCKLFLPDPVLRLKGIIGFGGHSTQWALWTKDGMAVVYPCHAVIIILRVDTRQQRFFLGHTDKVSALALDRNDALLASAQVQPPSMVRLWDFQTGACLSLFRSPLHTVCSLSFSGSGALLCGVGKDRHGRTVVVAWGTDQVGLGGEVVVLAKVHTDFDIQAFRIAFFDETRMASCGRGSVRLWRLRGGALRSCAVDLGEYCALELTDLAFAQALDGHQASLAGILFVCSHSGHILEIDHQRMAVRHIRRLLPTQSPGVPLTEKQSFSVGSGIAISSLGVSTTTCAVGSEDGYLRLWPLDFSSVLLEAEHDGPVSSVSFSPDGMRVLSTTTSGHLGFLDIPSREYTVLTRSHMAPVLALSTEQNRGQMATVSLDHTVRIWDLATLQQLYDFSSSDETPCAVAFHPTLPNFFCGFSSGAVRSFSLENSEVLVEHTRHRGTITSLVITPDGRFLFSSCSQGSLVQYNCSVSRCCVLRVAANVVCQDGRPKPNILAVSGDSCRLAIVGPSKCTVTVMESASLDELLRVDVSTLNLASNHLDWAVAVCFSPGDSSHLLVSTSSNKVVVLDAVSGHTLRKFSSVRSRACPSLALSVDARLLLAATGRTITVWDYPTQPNSSCQVYIGHSEPVRVVAFTPDQKQVLSVGDAIFLWDVLDIPESDQNESGAFSVHEPDSIAGQLEDLASGASGLPRLQVPIPSQASPPPLSIHDRPLEDSAGTFSTSDEEGLCEENHVSEALLQAQAPTPPVLVEREASGAGDGSRQAAKGSWAPAVVPYHPSQTSDWSLRRVKPGLPTRPDSYKHFTARYKASTRVKSVSFPPVGREQLRLKAVVGYNGNGRVNMVWRPDTGFFAYTCGRLVVVEDLHSGTQRHWLGHPQEISTLALNQDGQVLASASCCGNTATRCQIRIWDVSKGLCQHLLSHHDTAIQALAFSPDDEFLVTLGDYADLTLVLWSTATYELLSSTRLPEPVHGVAFNPWDANELISVGTSAITFWLLQHNGTDTSFQVHREPVPEELGASELTSLCYGASPLLYCGSSSGQVCVWDTGTSRCFLAWEADEGEIGVLLCSGSRLVSGSNTKRLRLWAVGVVPELRRKGSSARSSSVFMERELTLDGAIVSASFDSGMDMGVVGTTAGTLWYISWTEGTSTRLISGHRSKVNEVVFSPNESHCATCGEDGSVRVWSLASMELVIQFQVLNQSCLCLAWTPPSCGRPEQQQVVAGYSDGTLRVFSISRTAMELKMHPHRTALTAIAFSSDGQTILSGDKDGLVAISHPCTGMTFRVLSDHRGAPISAIQSISKEYGDLGVEGVDLWLAASGDQRVSVWASDWLRDRCELLEWLSFPAPATSEALGLLPPSLAAFCPWDRAILVCVGLGAHEEVIFYSLRQKQVVQKTPLPFFAMSLSLSPGAQLMVVGFAECMLRLLDCESGTAQDFEGHDDSVHLCRFTPSGRLLFTAAHNEILVWEVTSPSP", "length": 1609, "header": "tr|A0A9J7KA72-1|A0A9J7KA72_CRIGR Computationally mapped isoform of WD repeat-containing protein 90 OS=Cricetulus griseus OX=10029 GN=Wdr90 PE=3 SV=1 CANONICAL=A0A9J7GB34-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1168, "start_aa": "Thr", "end_pos": 1168, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1168", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760189", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760189", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34" } ], "pmid": "" }, { "name": "centriole", "id": "GO:0005814", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell projection organization", "id": "GO:0030030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030030", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB34" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1040, "end_pos": 1042, "annotation": "n_glycosylation_sequon" }, { 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"https://www.ncbi.nlm.nih.gov/protein/XP_027281779" }, "gene_names": [ { "name": "Tmem175", "type": "recommended", "evidence": [ { "id": "A0A9J7GCA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7" } ] }, { "name": "Tmem175", "type": "synonym", "evidence": [ { "id": "XP_027281779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281779" } ] } ], "protein_names": [ { "name": "Endosomal/lysosomal proton channel TMEM175", "type": "recommended", "evidence": [ { "id": "A0A9J7GCA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7/entry#names_and_taxonomy" } ] }, { "name": "Potassium channel TMEM175", "type": "synonym", "evidence": [ { "id": "A0A9J7GCA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 175", "type": "synonym", "evidence": [ { "id": "A0A9J7GCA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7/entry#names_and_taxonomy" } ] }, { "name": "endosomal/lysosomal potassium channel TMEM175 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027281779", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281779" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281779" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem175", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7", "locus": {} } ], "crossref": [ { "id": "100767371", "url": "https://www.ncbi.nlm.nih.gov/gene/100767371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767371", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCA7", "url": "https://www.orthodb.org/?gene=A0A9J7GCA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31462:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31462:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281779", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281779", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34979", "url": "https://www.rhea-db.org/rhea/34979", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GB39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB39-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC70-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JWM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JWM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JY69", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JY69-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBM5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRPQTEEQAVDSEGDSSLHRRDEEGTQSSHRMLGFSDALLSIIATVMILPVTHTEISPEQQFDKSIQKLLATRIAVYLMTFLIVTVAWAAHTRLFQVVGKIDDTLALLNLACMMTITLLPYTFSLMVTFPDVPLGIFLFCVCVIAIGSVQALIVGYAFHFPHLLNLQIQCSTYRAQSRRHILRLVLRGPALCFVAAVFSLFFFPLSYVLMVTVIFLPHISKATTWCKDKLMGHRESPAHNVEPFSIDLHAPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPKDVQEKFSGSLVAALGAYGPQFLAYFGSFATVGLLWFAHHSLFLHVRKATQTMGLLNILSLAFVGGLPLAYQQTSAFARQPRDELERVRVSCAIIFFASIFQFAIWTAALLHQTETLQPAVRFGGQEHAFMFAKLALYPCASLLAFAATCLLSRFSTAIFHLMQIAVPFAFLLLRLLVRLTLAALQVLWNLRPEHPQPGQGEPEAQSQLLPAPC", "length": 499, "header": "tr|A0A9J7GCA7-1|A0A9J7GCA7_CRIGR Isoform 1 of Endosomal/lysosomal proton channel TMEM175 OS=Cricetulus griseus OX=10029 GN=Tmem175 PE=3 SV=1 CANONICAL=A0A9J7GCA7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GB39-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7/entry#A0A9J7GB39-1", "sequence": { "sequence": "MSRPQTEEQAVDSEGDSSLHRRDEEGTQSSHRMLGFSDALLSIIATVMILPVTHTEISPEQQFDKSIQKLLATRIAVYLMTFLIVTVAWAAHTRLFQVVGKIDDTLALLNLACMMTITLLPYTSYVLMVTVIFLPHISKATTWCKDKLMGHRESPAHNVEPFSIDLHAPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPKDVQEKFSGSLVAALGAYGPQFLAYFGSFATVGLLWFAHHSLFLHVRKATQTMGLLNILSLAFVGGLPLAYQQTSAFARQPRDELERVRVSCAIIFFASIFQFAIWTAALLHQTETLQPAVRFGGQEHAFMFAKLALYPCASLLAFAATCLLSRFSTAIFHLMQIAVPFAFLLLRLLVRLTLAALQVLWNLRPEHPQPGQGEPEAQSQLLPAPC", "length": 416, "header": "tr|A0A9J7GB39-1|A0A9J7GCA7_CRIGR Computationally mapped isoform of Endosomal/lysosomal proton channel TMEM175 OS=Cricetulus griseus OX=10029 GN=Tmem175 PE=3 SV=1 CANONICAL=A0A9J7GCA7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7/entry#A0A9J7GBD2-1", "sequence": { "sequence": "MTFLIVTVAWAAHTRLFQVVGKIDDTLALLNLACMMTITLLPYTFSLMVTFPDVPLGIFLFCVCVIAIGSVQALIVGYAFHFPHLLNLQIQCSTYRAQSRRHILRLVLRGPALCFVAAVFSLFFFPLSYVLMVTVIFLPHISKATTWCKDKLMGHRESPAHNVEPFSIDLHAPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPKDVQEKFSGSLVAALGAYGPQFLAYFGSFATVGLLWFAHHSLFLHVRKATQTMGLLNILSLAFVGGLPLAYQQTSAFARQPRDELERVRVSCAIIFFASIFQFAIWTAALLHQTETLQPAVRFGGQEHAFMFAKLALYPCASLLAFAATCLLSRFSTAIFHLMQIAVPFAFLLLRLLVRLTLAALQVLWNLRPEHPQPGQGEPEAQSQLLPAPC", "length": 420, "header": "tr|A0A9J7GBD2-1|A0A9J7GBD2_CRIGR Computationally mapped isoform of Endosomal/lysosomal proton channel TMEM175 OS=Cricetulus griseus OX=10029 GN=Tmem175 PE=3 SV=1 CANONICAL=A0A9J7GCA7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GC70-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7/entry#A0A9J7GC70-1", "sequence": { "sequence": "MSRPQTEEQAVDSEGDSSLHRRDEEGTQSSHRMLGFSDALLSIIATVMILPVTHTEISPEQQFDKSIQKLLATRIAVYLMTFLIVTVAWAAHTRLFQVVGKIDDTLALLNLACMMTITLLPYTFSLMVTFPDVPLGIFLFCVCVIAIGSVQSYVLMVTVIFLPHISKATTWCKDKLMGHRESPAHNVEPFSIDLHAPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPKDVQEKFSGSLVAALGAYGPQFLAYFGSFATVGLLWFAHHSLFLHVRKATQTMGLLNILSLAFVGGLPLAYQQTSAFARQPRDELERVRVSCAIIFFASIFQFAIWTAALLHQTETLQPAVRFGGQEHAFMFAKLALYPCASLLAFAATCLLSRFSTAIFHLMQIAVPFAFLLLRLLVRLTLAALQVLWNLRPEHPQPGQGEPEAQSQLLPAPC", "length": 444, "header": "tr|A0A9J7GC70-1|A0A9J7GC70_CRIGR Computationally mapped isoform of Endosomal/lysosomal proton channel TMEM175 OS=Cricetulus griseus OX=10029 GN=Tmem175 PE=3 SV=1 CANONICAL=A0A9J7GCA7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7/entry#A0A9J7GCA7-1", "sequence": { "sequence": "MSRPQTEEQAVDSEGDSSLHRRDEEGTQSSHRMLGFSDALLSIIATVMILPVTHTEISPEQQFDKSIQKLLATRIAVYLMTFLIVTVAWAAHTRLFQVVGKIDDTLALLNLACMMTITLLPYTFSLMVTFPDVPLGIFLFCVCVIAIGSVQALIVGYAFHFPHLLNLQIQCSTYRAQSRRHILRLVLRGPALCFVAAVFSLFFFPLSYVLMVTVIFLPHISKATTWCKDKLMGHRESPAHNVEPFSIDLHAPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPKDVQEKFSGSLVAALGAYGPQFLAYFGSFATVGLLWFAHHSLFLHVRKATQTMGLLNILSLAFVGGLPLAYQQTSAFARQPRDELERVRVSCAIIFFASIFQFAIWTAALLHQTETLQPAVRFGGQEHAFMFAKLALYPCASLLAFAATCLLSRFSTAIFHLMQIAVPFAFLLLRLLVRLTLAALQVLWNLRPEHPQPGQGEPEAQSQLLPAPC", "length": 499, "header": "tr|A0A9J7GCA7-1|A0A9J7GCA7_CRIGR Isoform 1 of Endosomal/lysosomal proton channel TMEM175 OS=Cricetulus griseus OX=10029 GN=Tmem175 PE=3 SV=1 CANONICAL=A0A9J7GCA7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JWM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7/entry#A0A9J7JWM5-1", "sequence": { "sequence": "MSRPQTEEQAVDSEGDSSLHRRDEEGTQSSHRMLGFSDALLSIIATVMILPVTHTEISPEQQFDKSIQKLLATRIAVYLMTFLIVTVAWAAHTRLFQVVGKIDDTLALLNLACMMTITLLPYTALIVGYAFHFPHLLNLQIQCSTYRAQSRRHILRLVLRGPALCFVAAVFSLFFFPLSYVLMVTVIFLPHISKATTWCKDKLMGHRESPAHNVEPFSIDLHAPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPKDVQEKFSGSLVAALGAYGPQFLAYFGSFATVGLLWFAHHSLFLHVRKATQTMGLLNILSLAFVGGLPLAYQQTSAFARQPRDELERVRVSCAIIFFASIFQFAIWTAALLHQTETLQPAVRFGGQEHAFMFAKLALYPCASLLAFAATCLLSRFSTAIFHLMQIAVPFAFLLLRLLVRLTLAALQVLWNLRPEHPQPGQGEPEAQSQLLPAPC", "length": 471, "header": "tr|A0A9J7JWM5-1|A0A9J7JWM5_CRIGR Computationally mapped isoform of Endosomal/lysosomal proton channel TMEM175 OS=Cricetulus griseus OX=10029 GN=Tmem175 PE=3 SV=1 CANONICAL=A0A9J7GCA7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JY69-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7/entry#A0A9J7JY69-1", "sequence": { "sequence": "MSRPQTEEQAVDSEGDSSLHRRDEEGTQSSHRMLGFSDALLSIIATVMILPVTHTEISPEQFDKSIQKLLATRIAVYLMTFLIVTVAWAAHTRLFQVVGKIDDTLALLNLACMMTITLLPYTFSLMVTFPDVPLGIFLFCVCVIAIGSVQALIVGYAFHFPHLLNLQIQCSTYRAQSRRHILRLVLRGPALCFVAAVFSLFFFPLSYVLMVTVIFLPHISKATTWCKDKLMGHRESPAHNVEPFSIDLHAPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPKDVQEKFSGSLVAALGAYGPQFLAYFGSFATVGLLWFAHHSLFLHVRKATQTMGLLNILSLAFVGGLPLAYQQTSAFARQPRDELERVRVSCAIIFFASIFQFAIWTAALLHQTETLQPAVRFGGQEHAFMFAKLALYPCASLLAFAATCLLSRFSTAIFHLMQIAVPFAFLLLRLLVRLTLAALQVLWNLRPEHPQPGQGEPEAQSQLLPAPC", "length": 498, "header": "tr|A0A9J7JY69-1|A0A9J7JY69_CRIGR Computationally mapped isoform of Endosomal/lysosomal proton channel TMEM175 OS=Cricetulus griseus OX=10029 GN=Tmem175 PE=3 SV=1 CANONICAL=A0A9J7GCA7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7/entry#A0A9J7KBM5-1", "sequence": { "sequence": "MGSTYQACMMTITLLPYTFSLMVTFPDVPLGIFLFCVCVIAIGSVQALIVGYAFHFPHLLNLQIQCSTYRAQSRRHILRLVLRGPALCFVAAVFSLFFFPLSYVLMVTVIFLPHISKATTWCKDKLMGHRESPAHNVEPFSIDLHAPLSKERVEAFSDGVYAIVATLLILDICEDNVPDPKDVQEKFSGSLVAALGAYGPQFLAYFGSFATVGLLWFAHHSLFLHVRKATQTMGLLNILSLAFVGGLPLAYQQTSAFARQPRDELERVRVSCAIIFFASIFQFAIWTAALLHQTETLQPAVRFGGQEHAFMFAKLALYPCASLLAFAATCLLSRFSTAIFHLMQIAVPFAFLLLRLLVRLTLAALQVLWNLRPEHPQPGQGEPEAQSQLLPAPC", "length": 394, "header": "tr|A0A9J7KBM5-1|A0A9J7KBM5_CRIGR Computationally mapped isoform of Endosomal/lysosomal proton channel TMEM175 OS=Cricetulus griseus OX=10029 GN=Tmem175 PE=3 SV=1 CANONICAL=A0A9J7GCA7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB39" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB39", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB39" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767371", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "potassium channel activity", "id": "GO:0005267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005267", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7" } ], "pmid": "" }, { "name": "proton channel activity", "id": "GO:0015252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015252", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "34979", "name": "", "equation": "H(+)(in) = H(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34979", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34979" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GB45-1", "uniprot_ac": "A0A9J7GB45", "uniprot_id": "A0A9J7GB45_CRIGR", "mass": { "chemical_mass": 128625.0, "monoisotopic_mass": 128625.0 }, "refseq": { "ac": "XP_027280911", "name": "calpain-15 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280911" }, "gene_names": [ { "name": "Capn15", "type": "recommended", "evidence": [ { "id": "A0A9J7GB45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45" } ] }, { "name": "Capn15", "type": "synonym", "evidence": [ { "id": "XP_027280911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280911" } ] } ], "protein_names": [ { "name": "Calpain-15", "type": "recommended", "evidence": [ { "id": "A0A9J7GB45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45/entry#names_and_taxonomy" } ] }, { "name": "Small optic lobes homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7GB45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45/entry#names_and_taxonomy" } ] }, { "name": "calpain-15 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027280911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280911" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280911" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Capn15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45", "locus": {} } ], "crossref": [ { "id": "A0A9J7GB45", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GB45", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763096", "url": "https://www.ncbi.nlm.nih.gov/gene/100763096", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001876", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001876", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763096", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763096", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HBK9", "url": "https://www.orthodb.org/?gene=A0A3L7HBK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GB45", "url": "https://www.orthodb.org/?gene=A0A9J7GB45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GB50", "url": "https://www.orthodb.org/?gene=A0A9J7GB50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183:SF382", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183:SF382", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00641", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00641", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280911", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HBK9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HBK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB45-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB50", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNM3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUA1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW15", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW15-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXJ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSSASSLAAETESDHGFPGGPPYPGPPTAAGWCRSGPGETVWGSALVTRQHPRPRARSHTHSPGSMAAVGEWSCARCTFLNPAGQRQCSICEAPRHKPDLDQILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLLPIINGVLPKPPTILVEPKGNCKEEAGPVRTAGLVAMEPARGHSEEEEEKKEQEDEGEGAESGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTGFHVVPAPSQPILPGESAEADSPSTSQGPTSTDQEPPRVLPFSSFSPTLQNNPVPRSRREVPPQLQPPVPEAAQSSTSTSSKGPPQGPGRAAAGASRLAELLSGKELLSGKRLSMLEEEAPESSPARCESCSDVIDLTGDTVRYTPASPSSPDFTTWSCARCTLRNPTTAPRCSVCGGSKLHGFQEHSEPPTHCPDCGADKPGPCVGSCGRAPSAHKAARLLPDRLGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGTTPLRRRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSSPVIHRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTASGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQGKGPSQMRPTPAFPPSEPQSPPTGKLLAPLSTPPTASSPSAGVSRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASRGTHSPPLTPDVAGLHGPRPL", "length": 1193, "header": "tr|A0A9J7GB45-1|A0A9J7GB45_CRIGR Isoform 1 of Calpain-15 OS=Cricetulus griseus OX=10029 GN=Capn15 PE=3 SV=1 CANONICAL=A0A9J7GB45-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HBK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45/entry#A0A3L7HBK9-1", "sequence": { "sequence": "MGSSASSLAAETESDHGFPGGPPYPGPPTAAGWCRSGPGETVWGSALVTRQHPRPRARSHTHSPGSMAAVGEWSCARCTFLNPAGQRQCSICEAPRHKPDLDQILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLLPIINGVLPKPPTILVEPKGNCKEEAGPVRTAGLVAMEPARGHSEEEEEKKEQEDEGEGAESGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTGFHVVPAPSQPILPGESAEADSPSTSQGPTSTDQEPPRVLPFSSFSPTLQNNPVPRSRREVPPQLQPPVPEAAQSSTSTSSKGPPQGPGRAAAGASRLAELLSGKELLSGKRLSMLEEEAPESSPARCESCSDVIDLTGDTVRYTPASPSSPDFTTWSCARCTLRNPTTAPRCSVCGGSKLHGFQEHSEPPTHCPDCGADKPGPCVGSCGRAPSAHKAARLLPDRLGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGTTPLRRRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTASGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQGKGPSQMRPTPAFPPSEPQSPPTGKLLAPLSTPPTASSPSAGVSRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASRGTHSPPLTPDVAGLHGPRPL", "length": 1188, "header": "tr|A0A3L7HBK9-1|A0A3L7HBK9_CRIGR Computationally mapped isoform of Calpain-15 OS=Cricetulus griseus OX=10029 GN=Capn15 PE=3 SV=1 CANONICAL=A0A9J7GB45-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB45-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45/entry#A0A9J7GB45-1", "sequence": { "sequence": "MGSSASSLAAETESDHGFPGGPPYPGPPTAAGWCRSGPGETVWGSALVTRQHPRPRARSHTHSPGSMAAVGEWSCARCTFLNPAGQRQCSICEAPRHKPDLDQILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLLPIINGVLPKPPTILVEPKGNCKEEAGPVRTAGLVAMEPARGHSEEEEEKKEQEDEGEGAESGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTGFHVVPAPSQPILPGESAEADSPSTSQGPTSTDQEPPRVLPFSSFSPTLQNNPVPRSRREVPPQLQPPVPEAAQSSTSTSSKGPPQGPGRAAAGASRLAELLSGKELLSGKRLSMLEEEAPESSPARCESCSDVIDLTGDTVRYTPASPSSPDFTTWSCARCTLRNPTTAPRCSVCGGSKLHGFQEHSEPPTHCPDCGADKPGPCVGSCGRAPSAHKAARLLPDRLGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGTTPLRRRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSSPVIHRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTASGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQGKGPSQMRPTPAFPPSEPQSPPTGKLLAPLSTPPTASSPSAGVSRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASRGTHSPPLTPDVAGLHGPRPL", "length": 1193, "header": "tr|A0A9J7GB45-1|A0A9J7GB45_CRIGR Isoform 1 of Calpain-15 OS=Cricetulus griseus OX=10029 GN=Capn15 PE=3 SV=1 CANONICAL=A0A9J7GB45-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45/entry#A0A9J7GB50-1", "sequence": { "sequence": "MGSSASSLAAETESDHGFPGGPPYPGPPTAAGWCRSGPGETVWGSALVTRQHPRPRARSHTHSPGSMAAVGEWSCARCTFLNPAGQRQCSICEAPRHKPDLDQILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLLPIINGVLPKPPTILVEPKGNCKEEAGPVRTAGLVAMEPARGHSEEEEEKKEQEDEGEGAESGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTGFHVVPAPSQPILPGESAEADSPSTSQGPTSTDQEPPRVLPFSSFSPTLQNNPVPRSRREVPPQLQPPVPEAAQSSTSTSSKGPPQGPGRAAAGASRLAELLSGKELLSGKRLSMLEEEAPESSPARCESCSDVIDLTGDTVRYTPASPSSPDFTTWSCARCTLRNPTTAPRCSVCGGSKLHGFQEHSEPPTHCPDCGADKPGPCVGSCGRAPSAHKAARLLPDRLGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGTTPLRRRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTASGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQASSPSAGVSRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASRGTHSPPLTPDVAGLHGPRPL", "length": 1153, "header": "tr|A0A9J7GB50-1|A0A9J7GB50_CRIGR Computationally mapped isoform of Calpain-15 OS=Cricetulus griseus OX=10029 GN=Capn15 PE=3 SV=1 CANONICAL=A0A9J7GB45-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45/entry#A0A9J7JNM3-1", "sequence": { "sequence": "MGSSASSLAAETESDHGFPGGPPYPGPPTAAGWCRSGPGETVWGSALVTRQHPRPRARSHTHSPGSMAAVGEWSCARCTFLNPAGQRQCSICEAPRHKPDLDQILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLLPIINGVLPKPPTILVEPKGNCKEEAGPVRTAGLVAMEPARGHSEEEEEKKEQEDEGEGAESGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTGFHVVPAPSQPILPGESAEADSPSTSQGPTSTDQEPPRVLPFSSFSPTLQNNPVPRSRREVPPQLQPPVPEAAQSSTSTSSKGPPQGPGRAAAGASRLAELLSGKELLSGKRLSMLEEEAPESSPARCESCSDVIDLTGDTVRYTPASPSSPDFTTWSCARCTLRNPTTAPRCSVCGGSKLHGFQEHSEPPTHCPDCGADKPGPCVGSCGRAPSAHKAARLLPDRLGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGTTPLRRRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSSPVIHRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTASGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQGKGPSQMRPTPAFPPSEPQSPPTGKLLAPLSTPPTASSPSAGVSRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRSW", "length": 1137, "header": "tr|A0A9J7JNM3-1|A0A9J7JNM3_CRIGR Computationally mapped isoform of Calpain-15 OS=Cricetulus griseus OX=10029 GN=Capn15 PE=3 SV=1 CANONICAL=A0A9J7GB45-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JUA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45/entry#A0A9J7JUA1-1", "sequence": { "sequence": "MGSSASSLAAETESDHGFPGGPPYPGPPTAAGWCRSGPGETVWGSALVTRQHPRPRARSHTHSPGSMAAVGEWSCARCTFLNPAGQRQCSICEAPRHKPDLDQILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLLPIINGVLPKPPTILVEPKGNCKEEAGPVRTAGLVAMEPARGHSEEEEEKKEQEDEGEGAESGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTGFHVVPAPSQPILPGESAEADSPSTSQGPTSTDQEPPRVLPFSSFSPTLQNNPVPRSRREVPPQLQPPVPEAAQSSTSTSSKGPPQGPGRAAAGASRLAELLSGKELLSGKRLSMLEEEAPESSPARCESCSDVIDLTGDTVRYTPASPSSPDFTTWSCARCTLRNPTTAPRCSVCGGSKLHGFQEHSEPPTHCPDCGADKPGPCVGSCGRAPSAHKAARLLPDRLGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGTTPLRRRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSSPVIHRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTASGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQASSPSAGVSRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASRGTHSPPLTPDVAGLHGPRPL", "length": 1158, "header": "tr|A0A9J7JUA1-1|A0A9J7JUA1_CRIGR Computationally mapped isoform of Calpain-15 OS=Cricetulus griseus OX=10029 GN=Capn15 PE=3 SV=1 CANONICAL=A0A9J7GB45-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JW15-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45/entry#A0A9J7JW15-1", "sequence": { "sequence": "MGSSASSLAAETESDHGFPGGPPYPGPPTAAGWCRSGPGETVWGSALVTRQHPRPRARSHTHSPGSMAAVGEWSCARCTFLNPAGQRQCSICEAPRHKPDLDQILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLLPIINGVLPKPPTILVEPKGNCKEEAGPVRTAGLVAMEPARGHSEEEEEKKEQEDEGEGAESGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTGFHVVPAPSQPILPGESAEADSPSTSQGPTSTDQEPPRVLPFSSFSPTLQNNPVPRSRREVPPQLQPPVPEAAQSSTSTSSKGPPQGPGRAAAGASRLAELLSGKELLSGKRLSMLEEEAPESSPARCESCSDVIDLTGDTVRYTPASPSSPDFTTWSCARCTLRNPTTAPRCSVCGGSKLHGFQEHSEPPTHCPDCGADKPGPCVGSCGRAPSAHKAARLLPDRLGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGTTPLRRRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSSPVIHRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTASGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQGP", "length": 986, "header": "tr|A0A9J7JW15-1|A0A9J7JW15_CRIGR Computationally mapped isoform of Calpain-15 OS=Cricetulus griseus OX=10029 GN=Capn15 PE=3 SV=1 CANONICAL=A0A9J7GB45-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45/entry#A0A9J7JXJ3-1", "sequence": { "sequence": "MAAVGEWSCARCTFLNPAGQRQCSICEAPRHKPDLDQILRLSVEEQKWPCARCTFRNFLGKEACEVCGFTPEPVPGAPLLPIINGVLPKPPTILVEPKGNCKEEAGPVRTAGLVAMEPARGHSEEEEEKKEQEDEGEGAESGSGWACQRCTLHNTPVASSCSACGGPRKLSLPRIPPEALVVPEVVAPTGFHVVPAPSQPILPGESAEADSPSTSQGPTSTDQEPPRVLPFSSFSPTLQNNPVPRSRREVPPQLQPPVPEAAQSSTSTSSKGPPQGPGRAAAGASRLAELLSGKELLSGKRLSMLEEEAPESSPARCESCSDVIDLTGDTVRYTPASPSSPDFTTWSCARCTLRNPTTAPRCSVCGGSKLHGFQEHSEPPTHCPDCGADKPGPCVGSCGRAPSAHKAARLLPDRLGQWACPACTLINTPRAKHCAACHTPQLLVTQCRGTTPLRRRESMHVEKRRQTDEGEAKALWENIVAFCRENSVNFVDDSFPPGPASVGFPVGDSVQQRVKQWLRPHEINCSVFRDHGTPWSVFHTLRPSDILQGLLGNCWFLSALAVLAERPDLVERVMVTRSLCAEGAYQVRLCKDGTWTTVLVDDMLPCDEAGFLLFSQAQRKQLWVALIEKALAKLHGSYFALQAGRAIEGLATLTGAPCESLALQVSSTNPREEPVDTDLIWAKMLSSKEAGFLMGASCGGGNMKVDDAAYESLGLRPRHAYSVLDVRDVQGSSPVIHRLLRLRNPWGRFSWNGSWSDEWPHWPGHLRAELMPHGSSEGVFWMEYSDFIRYFDSVDICKVHSDWQEARVQGCFPSTASGPVGVTALTVLERASLEFALFQEGSRRSDSVDSHLLDLCILVFRATFGTGGRLSLGRLLAHSKRAVKKFVNCDVMLEPGEYAVVCCAFNHWNPAPPGPPAQGKGPSQMRPTPAFPPSEPQSPPTGKLLAPLSTPPTASSPSAGVSRGAPEPPGHVLAVYSSRLVMVEPVEAQPTTLADAIILLTESRGERHEGREGMTCYYLTHGWAGLIVVVENRHPKSYLHVQCDCTDSFNVVSTRGSLRTQDSVPPLHRQVLVILSQLEGNAGFSITHRLAHRKAAQAFLSDWTASRGTHSPPLTPDVAGLHGPRPL", "length": 1127, "header": "tr|A0A9J7JXJ3-1|A0A9J7JXJ3_CRIGR Computationally mapped isoform of Calpain-15 OS=Cricetulus griseus OX=10029 GN=Capn15 PE=3 SV=1 CANONICAL=A0A9J7GB45-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 29, "start_aa": "Thr", "end_pos": 29, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr29", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 994, "start_aa": "Thr", "end_pos": 994, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr994", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763096", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763096", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium-dependent cysteine-type endopeptidase activity", "id": "GO:0004198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004198", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB45", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 818, "end_pos": 820, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 29, 994 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 590, "end_pos": 592 }, { "start_pos": 818, "end_pos": 820 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", 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"uniprot_canonical_ac": "A0A9J7GB46-1", "uniprot_ac": "A0A9J7GB46", "uniprot_id": "A0A9J7GB46_CRIGR", "mass": { "chemical_mass": 12639.0, "monoisotopic_mass": 12639.0 }, "refseq": { "ac": "XP_007639747", "name": "40S ribosomal protein S3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639747" }, "gene_names": [ { "name": "LOC100773119", "type": "recommended", "evidence": [ { "id": "A0A9J7GB46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46" } ] }, { "name": "LOC100773119", "type": "synonym", "evidence": [ { "id": "XP_007639747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639747" } ] } ], "protein_names": [ { "name": "40S ribosomal protein S3", "type": "recommended", "evidence": [ { "id": "A0A9J7GB46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46/entry#names_and_taxonomy" } ] }, { "name": "40S ribosomal protein S3", "type": "synonym", "evidence": [ { "id": "XP_007639747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639747" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613815.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007639747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639747" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773119", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46", "locus": {} } ], "crossref": [ { "id": "A0A9J7GB46", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GB46", "database": "AlphaFoldDB", "categories": [] }, { "id": "100773119", "url": "https://www.ncbi.nlm.nih.gov/gene/100773119", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036419", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036419", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773119", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773119", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GB46", "url": "https://www.orthodb.org/?gene=A0A9J7GB46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11760:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11760:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007639747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639747", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGAEGCEVVVSGKLRGERAKSMKLVDGLMIHSGDPVNYYVDTAIRHVLLRQGVLGIKVKIMLPWDPSGKIGPKKPLPDHVSIMEPKDEILPTTPISQQKGGKPEPPAMPQPVPTP", "length": 117, "header": "tr|A0A9J7GB46-1|A0A9J7GB46_CRIGR Isoform 1 of 40S ribosomal protein S3 OS=Cricetulus griseus OX=10029 GN=LOC100773119 PE=3 SV=1 CANONICAL=A0A9J7GB46-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GB46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46/entry#A0A9J7GB46-1", "sequence": { "sequence": "MESGAEGCEVVVSGKLRGERAKSMKLVDGLMIHSGDPVNYYVDTAIRHVLLRQGVLGIKVKIMLPWDPSGKIGPKKPLPDHVSIMEPKDEILPTTPISQQKGGKPEPPAMPQPVPTP", "length": 117, "header": "tr|A0A9J7GB46-1|A0A9J7GB46_CRIGR Isoform 1 of 40S ribosomal protein S3 OS=Cricetulus griseus OX=10029 GN=LOC100773119 PE=3 SV=1 CANONICAL=A0A9J7GB46-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 116, "start_aa": "Thr", "end_pos": 116, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr116", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A9J7GB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of apoptotic signaling pathway", "id": "GO:2001235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001235", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46" } ], "pmid": "" }, { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB46" } ], "pmid": "" } ] } ] }, 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613646.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027246880.1. 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"mass": { "chemical_mass": 64886.0, "monoisotopic_mass": 64886.0 }, "refseq": { "ac": "XP_027281687", "name": "DBIRD complex subunit ZNF326 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281687" }, "gene_names": [ { "name": "Znf326", "type": "recommended", "evidence": [ { "id": "A0A9J7GB86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86" } ] }, { "name": "Znf326", "type": "synonym", "evidence": [ { "id": "XP_027281687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281687" } ] } ], "protein_names": [ { "name": "DBIRD complex subunit ZNF326", "type": "recommended", "evidence": [ { "id": "A0A9J7GB86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86/entry#names_and_taxonomy" } ] }, { "name": "DBIRD complex subunit ZNF326 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027281687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281687" } ] }, { "name": "Zinc finger protein 326", "type": "synonym", "evidence": [ { "id": "A0A9J7GB86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281687" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf326", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86", "locus": {} } ], "crossref": [ { "id": "A0A9J7GB86", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GB86", "database": "AlphaFoldDB", "categories": [] }, { "id": "100767973", "url": "https://www.ncbi.nlm.nih.gov/gene/100767973", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034736", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034736", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767973", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767973", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GB86", "url": "https://www.orthodb.org/?gene=A0A9J7GB86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12190", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12190", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12190:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12190:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04988", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04988", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281687", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HXY5", "url": "https://www.uniprot.org/uniprotkb/A0A061HXY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HXY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HXY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GB86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0L0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0L0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KA30", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KA30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KA30-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KA30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFEDDYIHSASRNTYQGFNGMDRDYGPGSYGGLDRDYGHGSYGGQRSMDSYLSQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEEPYSRSKLRPGFMEDTGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFGSVHRPGIIVDYQNKSTSVTIATTRGIKRKVMQIFNKPGGAFIKKPKLAKPLEKMNLSKSPAKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVIMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDVMEGVTADDHMMKVETVHCSACSVYIPAFHSSVQQHLKSPDHVKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQIEGDEEDEEKINEPVEEEEDEEDDGEEGEEGEEAEEEDEEVEEGGETEEVEEEERGEAAEGGEGTPESGEEGAEVEEEGKEESAGCPAEQCEQSG", "length": 577, "header": "tr|A0A9J7GB86-1|A0A9J7GB86_CRIGR Isoform 1 of DBIRD complex subunit ZNF326 OS=Cricetulus griseus OX=10029 GN=Znf326 PE=3 SV=1 CANONICAL=A0A9J7GB86-1" }, "isoforms": [ { "isoform_ac": "A0A061HXY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86/entry#A0A061HXY5-1", "sequence": { "sequence": "MILMSFTGMDRDYGPGSYGGLDRDYGHGSYGGQRSMDSYLSQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEEPYSRSKLRPGFMEDTGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFGSVHRPGIIVDYQNKSTSVTIATTRGIKRKVMQIFNKPGGAFIKKPKLAKPLEKMNLSKSPAKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVIMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDVMEGVTADDHMMKVETVHCSACSVYIPAFHSSVQQHLKSPDHVKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQIEGDEEDEEKINEPVEEEEDEEDDGEEGEEGEEAEEEDEEVEEGGETEEVEEEERGEAAEGGEGTPESGEEGAEVEEEGKEESAGCPAEQCEQSG", "length": 564, "header": "tr|A0A061HXY5-1|A0A061HXY5_CRIGR Computationally mapped isoform of DBIRD complex subunit ZNF326 OS=Cricetulus griseus OX=10029 GN=Znf326 PE=3 SV=1 CANONICAL=A0A9J7GB86-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GB86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86/entry#A0A9J7GB86-1", "sequence": { "sequence": "MDFEDDYIHSASRNTYQGFNGMDRDYGPGSYGGLDRDYGHGSYGGQRSMDSYLSQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEEPYSRSKLRPGFMEDTGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFGSVHRPGIIVDYQNKSTSVTIATTRGIKRKVMQIFNKPGGAFIKKPKLAKPLEKMNLSKSPAKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVIMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDVMEGVTADDHMMKVETVHCSACSVYIPAFHSSVQQHLKSPDHVKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQIEGDEEDEEKINEPVEEEEDEEDDGEEGEEGEEAEEEDEEVEEGGETEEVEEEERGEAAEGGEGTPESGEEGAEVEEEGKEESAGCPAEQCEQSG", "length": 577, "header": "tr|A0A9J7GB86-1|A0A9J7GB86_CRIGR Isoform 1 of DBIRD complex subunit ZNF326 OS=Cricetulus griseus OX=10029 GN=Znf326 PE=3 SV=1 CANONICAL=A0A9J7GB86-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K0L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86/entry#A0A9J7K0L0-1", "sequence": { "sequence": "MDFEDDYIHSASRNTYQGFNGMDRDYGPGSYGGLTFQDIYLKILLLSASKGLDLMSLTTPGLLWVGEICTDLAMVLMNPNKAASEVVMVVDLRAPTGIALTLSEPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFGSVHRPGIIVDYQNKSTSVTIATTRGIKRKVMQIFNKPGGAFIKKPKLAKPLEKMNLSKSPAKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVIMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDVMEGVTADDHMMKVETVHCSACSVYIPAFHSSVQQHLKSPDHVKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQIEGDEEDEEKINEPVEEEEDEEDDGEEGEEGEEAEEEDEEVEEGGETEEVEEEERGEAAEGGEGTPESGEEGAEVEEEGKEESAGCPAEQCEQSG", "length": 515, "header": "tr|A0A9J7K0L0-1|A0A9J7K0L0_CRIGR Computationally mapped isoform of DBIRD complex subunit ZNF326 OS=Cricetulus griseus OX=10029 GN=Znf326 PE=3 SV=1 CANONICAL=A0A9J7GB86-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KA30-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86/entry#A0A9J7KA30-1", "sequence": { "sequence": "MAWTITVVVVGVAGLDLMSLTTPGLLWVGEICTDLAMVLMNPNKAASEVVMVVDLRAPTGIALTLSEPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFGSVHRPGIIVDYQNKSTSVTIATTRGIKRKVMQIFNKPGGAFIKKPKLAKPLEKMNLSKSPAKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVIMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDVMEGVTADDHMMKVETVHCSACSVYIPAFHSSVQQHLKSPDHVKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQIEGDEEDEEKINEPVEEEEDEEDDGEEGEEGEEAEEEDEEVEEGGETEEVEEEERGEAAEGGEGTPESGEEGAEVEEEGKEESAGCPAEQCEQSG", "length": 478, "header": "tr|A0A9J7KA30-1|A0A9J7KA30_CRIGR Computationally mapped isoform of DBIRD complex subunit ZNF326 OS=Cricetulus griseus OX=10029 GN=Znf326 PE=3 SV=1 CANONICAL=A0A9J7GB86-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86/entry#A0A9J7KBJ5-1", "sequence": { "sequence": "MILMSFTGMDRDYGPGSYGGLTFQDIYLKILLLSASKGLDLMSLTTPGLLWVGEICTDLAMVLMNPNKAASEVVMVVDLRAPTGIALTLSEPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFGSVHRPGIIVDYQNKSTSVTIATTRGIKRKVMQIFNKPGGAFIKKPKLAKPLEKMNLSKSPAKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVIMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDVMEGVTADDHMMKVETVHCSACSVYIPAFHSSVQQHLKSPDHVKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQIEGDEEDEEKINEPVEEEEDEEDDGEEGEEGEEAEEEDEEVEEGGETEEVEEEERGEAAEGGEGTPESGEEGAEVEEEGKEESAGCPAEQCEQSG", "length": 502, "header": "tr|A0A9J7KBJ5-1|A0A9J7KBJ5_CRIGR Computationally mapped isoform of DBIRD complex subunit ZNF326 OS=Cricetulus griseus OX=10029 GN=Znf326 PE=3 SV=1 CANONICAL=A0A9J7GB86-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767973", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767973", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription elongation", "id": "GO:0032784", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032784", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GB86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GB86" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear matrix", "id": "GO:0016363", "url": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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} ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 291, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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"https://www.ncbi.nlm.nih.gov/protein/XP_027241635" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 94 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613637.1) and transcript sequence (IACG01089938.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027241635", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241635" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Csnk1d", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4", "locus": {} } ], "crossref": [ { "id": "A0A9J7GBF4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GBF4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14125", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14125", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751124", "url": "https://www.ncbi.nlm.nih.gov/gene/100751124", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751124", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GBF4", "url": "https://www.orthodb.org/?gene=A0A9J7GBF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027241635", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027241635", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2MNT4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MNT4", "database": "UniProtKB", 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"sequence": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNVSSSDLTGRQDTSRMSTSQRSRDVASLRLHAARQGARCRPQRPRRTTY", "length": 428, "header": "tr|A0A9J7GBF4-1|A0A9J7GBF4_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1d PE=3 SV=1 CANONICAL=A0A9J7GBF4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MNT4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4/entry#A0A8C2MNT4-1", "sequence": { "sequence": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNVSSSDLTGRQDTSRMSTSQNSIPFEHHGK", "length": 409, "header": "tr|A0A8C2MNT4-1|A0A8C2MNT4_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1d PE=3 SV=1 CANONICAL=A0A9J7GBF4-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MNV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4/entry#A0A8C2MNV9-1", "sequence": { "sequence": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNVSSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR", "length": 415, "header": "tr|A0A8C2MNV9-1|A0A8C2MNV9_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1d PE=3 SV=1 CANONICAL=A0A9J7GBF4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4/entry#A0A9J7GBF4-1", "sequence": { "sequence": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNVSSSDLTGRQDTSRMSTSQRSRDVASLRLHAARQGARCRPQRPRRTTY", "length": 428, "header": "tr|A0A9J7GBF4-1|A0A9J7GBF4_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1d PE=3 SV=1 CANONICAL=A0A9J7GBF4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4/entry#A0A9J7JNR3-1", "sequence": { "sequence": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNVSSSDLTGRQDTSRMSTSQCLSGS", "length": 404, "header": "tr|A0A9J7JNR3-1|A0A9J7JNR3_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Csnk1d PE=3 SV=1 CANONICAL=A0A9J7GBF4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751124", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "pmid": "" }, { "name": "protein serine kinase activity", "id": "GO:0106310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0106310", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBF4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", 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"A0A9J7JGR2-1", "A0A8C2QLT0-1", "A0A9J7JYC5-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", 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"A0A9J7G270-1", "A0A9J7K1H4-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", "A0A8C2QHF9-1", "A0A8C2QI80-1", "A0A8C2QKP7-1", "A0A9J7FFS7-1", "A0A9J7FI14-1", "A0A9J7FJ23-1", "A0A9J7JLH7-1", "A0A8C2MH43-1", "A0A9J7FZ18-1", "A0A9J7G368-1", "A0A9J7G6S5-1", "A0A9J7H2T6-1", "A0A9J7H3N1-1", "A0A9J7H8L4-1", "A0A9J7JIW6-1", "A0A9J7JRI3-1", "A0A061ILI7-1", "A0A061HUS7-1", "A0A061HVM6-1", "A0A061I033-1", "A0A061I8L6-1", "A0A061I9F9-1", "A0A8C2MQS3-1", "A0A9J7F0Y2-1", "A0A9J7EZ49-1", "A0A8C2M6A3-1", "A0A8C2MQL9-1", "A0A8C2LY02-1", "A0A8C2LZT2-1", "A0A8C2M165-1", "A0A8C2M5G2-1", "A0A8C2M3Y9-1", "A0A8C2M5A7-1", "A0A8C2M9B6-1", "A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A8C2ML15-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", "A0A9J7KE81-1", "A0A9J7JPE2-1", "A0A9J7F773-1", "A0A8C2L7R1-1", "A0A8C2LHE9-1", "A0A3L7I870-1", "A0A3L7IB60-1", "A0A3L7IBX6-1", "A0A3L7ID00-1", "A0A3L7IEL5-1", "A0A3L7IER1-1", "A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMC9-1", "A0A8C2LMJ0-1", "A0A9J7JQV6-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "A0A8C2MYH0-1", "A0A8C2MV78-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N4W2-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A9J7F0N6-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F3R3-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7FLY5-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] } ] }, { "uniprot_ac": "A0A8C2N3U2", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ 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"id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2E9" } ] } ] }, { "uniprot_ac": "A0A9J7H2P9", "gene_name": "LOC113839030", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P9" } ] } ] }, { "uniprot_ac": "A0A9J7H2T6", "gene_name": "Ttn", "activity": [ { "ec_number": "2.7.11.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] } ] }, { "uniprot_ac": "G3IN30", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] } ] }, { "uniprot_ac": "O55076", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] } ] }, { "uniprot_ac": "P25321", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] } ] }, { "uniprot_ac": "P50310", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "P50310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P50310" } ] } ] }, { "uniprot_ac": "P68180", "gene_name": "PRKACB", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P68180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68180" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P68180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P68180" } ] } ] }, { "uniprot_ac": "Q63980", "gene_name": "MAP2K1", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q63980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q63980" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "Q63980", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q63980" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 277, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.11.1", "ec_name": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "2.7.11.1", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.11.1" }, { "id": "2.7.11.1", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.11.1" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 380, "end_pos": 382 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A9J7GBH2", "uniprot_id": "A0A9J7GBH2_CRIGR", "mass": { "chemical_mass": 239626.0, "monoisotopic_mass": 239626.0 }, "refseq": { "ac": "XP_003495730", "name": "protein sidekick-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495730" }, "gene_names": [ { "name": "Sdk2", "type": "recommended", "evidence": [ { "id": "A0A9J7GBH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2" } ] }, { "name": "Sdk2", "type": "synonym", "evidence": [ { "id": "XP_003495730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495730" } ] } ], "protein_names": [ { "name": "Protein sidekick-2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7GBH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2/entry#names_and_taxonomy" } ] }, { "name": "protein sidekick-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003495730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495730" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495730" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sdk2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2", "locus": {} } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751793", "url": "https://www.ncbi.nlm.nih.gov/gene/100751793", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751793", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751793", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GBH2", "url": "https://www.orthodb.org/?gene=A0A9J7GBH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GGI9", "url": "https://www.orthodb.org/?gene=A0A9J7GGI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13817", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13817", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13817:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13817:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495730", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GBH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GGI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GGI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWRLPIWTLLALHRIQSAGAQDDVPPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTRFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRISSFPRPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLAVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTMECVANARPLIKLHIIWRKDGALLSNGISDYNRRLTITNPTLSDAGYYECEAVLRSSSVSPVTRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCRAKGVPPPSITWYKDAALVEVEKLTRFKQRNDGGLQISGLLPDDTGMLQCFAHNAAGEAQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTVRYVWEKDGATLAVETNPRIRLDRNGSLHISQTWSGDIGTYTCRVLSAGGNDSRNAHLRVRQLPHAPEHPVATLSTMERRAINLTWAKPFDGNSPLMRYILEMSENNAPWTILLASVDPEATSVMVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPTQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSSPQLVRTHEDVPGPVGHLSFNDILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWVVEAQVGVIGEGEEWLLIYQLSNEPDARSMEVPDLNPFTYYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVTLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSQAVMGRTRESVPSSGPTNVSALATTSSSMLVRWSEIPEADRNGLVLGYKVRYKEKDSDSQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNATTANTATVEVLAPSARQYMATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPVVQQEDVKARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASAFTVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGAKWAELTSLYSMRNLTRPSLTQYELDNLSKHKRYEIRMSVYNAVGEGPLSPPQEVFVGEAVPTAAPQNVAIHSATATQLDVTWEPPPLDSQNGDIQGYKIYFWEVQRRNLTERVKTLFLAENSVKLKNLTGYTAYMVSIAAFNAAGDGPRSTPTRGQTQQAAPSAPGSVKFSELTTTSVNVSWEAPQFPNGPLEGYRLVYEPCTPVDGVSKIVTVDVKGTGPLWLKVKDLAEGMTYRFRIKAKTFTYGPEIEANITTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKASPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYSKKTDAGGNTKSGALGHGEMLSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDTNPQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHVTVPNSNSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2172, "header": "tr|A0A9J7GBH2-1|A0A9J7GBH2_CRIGR Isoform 1 of Protein sidekick-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sdk2 PE=3 SV=1 CANONICAL=A0A9J7GBH2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2/entry#A0A9J7GBH2-1", "sequence": { "sequence": "MWRLPIWTLLALHRIQSAGAQDDVPPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTRFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRISSFPRPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLAVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTMECVANARPLIKLHIIWRKDGALLSNGISDYNRRLTITNPTLSDAGYYECEAVLRSSSVSPVTRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCRAKGVPPPSITWYKDAALVEVEKLTRFKQRNDGGLQISGLLPDDTGMLQCFAHNAAGEAQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTVRYVWEKDGATLAVETNPRIRLDRNGSLHISQTWSGDIGTYTCRVLSAGGNDSRNAHLRVRQLPHAPEHPVATLSTMERRAINLTWAKPFDGNSPLMRYILEMSENNAPWTILLASVDPEATSVMVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPTQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSSPQLVRTHEDVPGPVGHLSFNDILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWVVEAQVGVIGEGEEWLLIYQLSNEPDARSMEVPDLNPFTYYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVTLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSQAVMGRTRESVPSSGPTNVSALATTSSSMLVRWSEIPEADRNGLVLGYKVRYKEKDSDSQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNATTANTATVEVLAPSARQYMATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPVVQQEDVKARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASAFTVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGAKWAELTSLYSMRNLTRPSLTQYELDNLSKHKRYEIRMSVYNAVGEGPLSPPQEVFVGEAVPTAAPQNVAIHSATATQLDVTWEPPPLDSQNGDIQGYKIYFWEVQRRNLTERVKTLFLAENSVKLKNLTGYTAYMVSIAAFNAAGDGPRSTPTRGQTQQAAPSAPGSVKFSELTTTSVNVSWEAPQFPNGPLEGYRLVYEPCTPVDGVSKIVTVDVKGTGPLWLKVKDLAEGMTYRFRIKAKTFTYGPEIEANITTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKASPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYSKKTDAGGNTKSGALGHGEMLSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDTNPQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHVTVPNSNSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2172, "header": "tr|A0A9J7GBH2-1|A0A9J7GBH2_CRIGR Isoform 1 of Protein sidekick-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sdk2 PE=3 SV=1 CANONICAL=A0A9J7GBH2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GGI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2/entry#A0A9J7GGI9-1", "sequence": { "sequence": "MWRLPIWTLLALHRIQSAGAQDDVPPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTRFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRISSFPRPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLAVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTMECVANARPLIKLHIIWRKDGALLSNGISDYNRRLTITNPTLSDAGYYECEAVLRSSSVSPVTRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCRAKGVPPPSITWYKDAALVEVEKLTRFKQRNDGGLQISGLLPDDTGMLQCFAHNAAGEAQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTLLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTVRYVWEKDGATLAVETNPRIRLDRNGSLHISQTWSGDIGTYTCRVLSAGGNDSRNAHLRVRQLPHAPEHPVATLSTMERRAINLTWAKPFDGNSPLMRYILEMSENNAPWTILLASVDPEATSVMVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPTQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSSPQLVRTHEDVPGPVGHLSFNDILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGAPTNLGISNIGPRSVTLQFRPGYDGKTSISRWVVEAQVGVIGEGEEWLLIYQLSNEPDARSMEVPDLNPFTYYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVTLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVEREYTIEDLEEWTEYRVQVQAFNAIGSGPWSQAVMGRTRESVPSSGPTNVSALATTSSSMLVRWSEIPEADRNGLVLGYKVRYKEKDSDSQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNATTANTATVEVLAPSARQYMATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSKPVVQQEDVKARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASAFTVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGAKWAELTYLSKHKRYEIRMSVYNAVGEGPLSPPQEVFVGEAVPTAAPQNVAIHSATATQLDVTWEPPPLDSQNGDIQGYKIYFWEVQRRNLTERVKTLFLAENSVKLKNLTGYTAYMVSIAAFNAAGDGPRSTPTRGQTQQAAPSAPGSVKFSELTTTSVNVSWEAPQFPNGPLEGYRLVYEPCTPVDGVSKIVTVDVKGTGPLWLKVKDLAEGMTYRFRIKAKTFTYGPEIEANITTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVTSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKASPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYSKKTDAGGNTKSGALGHGEMLSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDTNPQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHVTVPNSNSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPGSRAPIAGFSSFV", "length": 2153, "header": "tr|A0A9J7GGI9-1|A0A9J7GGI9_CRIGR Computationally mapped isoform of Protein sidekick-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Sdk2 PE=3 SV=1 CANONICAL=A0A9J7GBH2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 691, "start_aa": "Thr", "end_pos": 691, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr691", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751793", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751793", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBH2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1102, "end_pos": 1104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1205, "end_pos": 1207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1256, "end_pos": 1258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1341, "end_pos": 1343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1457, "end_pos": 1459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1575, "end_pos": 1577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1588, "end_pos": 1590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1670, "end_pos": 1672, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1689, "end_pos": 1691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1741, "end_pos": 1743, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1815, "end_pos": 1817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2119, "end_pos": 2121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" }, { "start_pos": 743, "end_pos": 745, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" }, { "start_pos": 936, "end_pos": 938, "annotation": "n_glycosylation_sequon" }, { "start_pos": 948, "end_pos": 950, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GBH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 592, "end_pos": 688, "start_aa": "Ala", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7GBH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 108, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 691 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1102, "end_pos": 1104 }, { "start_pos": 1205, "end_pos": 1207 }, { "start_pos": 1256, "end_pos": 1258 }, { "start_pos": 1341, "end_pos": 1343 }, { "start_pos": 1457, "end_pos": 1459 }, { "start_pos": 1575, "end_pos": 1577 }, { "start_pos": 1588, "end_pos": 1590 }, { "start_pos": 1670, "end_pos": 1672 }, { "start_pos": 1689, "end_pos": 1691 }, { "start_pos": 1741, "end_pos": 1743 }, { "start_pos": 1815, "end_pos": 1817 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 2119, "end_pos": 2121 }, { "start_pos": 223, "end_pos": 225 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 551, "end_pos": 553 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 704, "end_pos": 706 }, { "start_pos": 743, "end_pos": 745 }, { "start_pos": 804, "end_pos": 806 }, { "start_pos": 936, "end_pos": 938 }, { "start_pos": 948, "end_pos": 950 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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[ "Protein Classification" ] }, { "id": "PTHR22948:SF75", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22948:SF75", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00567", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00567", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10522", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10522", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282088", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282088", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GBK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBR1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIQFRSLFPLALPGMLALLGWWWFFSRKKDQLSSNDKQVETLKVGPVIKDQLPSDEACPRVLSMPPSVAQPPETEQLSVGKSSTALPRIRQVRRRSESSGNLPSNVDTRSQPCRDNNSKVELSLMGDEVKSIPLGCPLLPKEVPFPYEAVEGYKQESALGKIPGRGWLDQCAASGEKARETGGAEGTGDAVLGENIPEEGLLSQEYISEVEKSGVPNLAPWGGGGEKMSSGPPQVAELAKKEEFVVGKLPSSFVEPVRSEMVKDEDALVPQVRGGITQDRDLAREQIKEDTLPEKDQIEQAAFQIISRVILEVTEEMGAGKTVVQVYPTSVAQPQGLEESSVPASQETGLGRDIPDPVSTTTGATASPPAEALPPKTYVSCFSSPLSSPTKDQKPKTSAHHISLAPCPLPVTRLRQSLDAASSPGGDDTFVTCMSYNKQSVLSVTSSGQRSHSLTTSGLEDSCTKTISSPGDKAVTPPLPDSTEPFSNGVLKEELSDVGTEDGWTMDAEADHSGAACTIGHLRELKPSQGSDRNSMDSVDSCCGLPKPDSLQNVQASSNPKKVDLIVWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNVQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGVTVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSETGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSYYANL", "length": 862, "header": "tr|A0A9J7GBR1-1|A0A9J7GBR1_CRIGR Isoform 1 of A-kinase anchor protein 1, mitochondrial OS=Cricetulus griseus OX=10029 GN=Akap1 PE=4 SV=1 CANONICAL=A0A9J7GBR1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR1/entry#A0A9J7GBK8-1", "sequence": { "sequence": "MAIQFRSLFPLALPGMLALLGWWWFFSRKKDQLSSNDKQVETLKVGPVIKDQLPSDEACPRVLSMPPSVAQPPETEQLSVGKSSTALPRIRQVRRRSESSGNLPSNVDTRSQPCRDNNSKVELSLMGDEVKSIPLGCPLLPKEVPFPYEAVEGYKQESALGKIPGRGWLDQCAASGEKARETGGAEGTGDAVLGENIPEEGLLSQEYISEVEKSGVPNLAPWGGGGEKMSSGPPQVAELAKKEEFVVGKLPSSFVEPVRSEMVKDEDALVPQVRGGITQDRDLAREQIKEDTLPEKDQIEQAAFQIISRVILEVTEEMGAGKTVVQVYPTSVAQPQGLEESSVPASQETGLGRDIPDPVSTTTGATASPPAEALPPKTYVSCFSSPLSSPTKDQKPKTSAHHISLAPCPLPVTRLRQSLDAASSPGGDDTFVTCMSYNKQSVLSVTSSGQRSHSLTTSGLEDSCTKTISSPGDKAVTPPLPDSTEPFSNGVLKEELSDVGTEDGWTMDAEADHSGGSDRNSMDSVDSCCGLPKPDSLQNVQASSNPKKVDLIVWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNVQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGVTVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSETGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSYYANL", "length": 847, "header": "tr|A0A9J7GBK8-1|A0A9J7GBR1_CRIGR Computationally mapped isoform of A-kinase anchor protein 1, mitochondrial OS=Cricetulus griseus OX=10029 GN=Akap1 PE=4 SV=1 CANONICAL=A0A9J7GBR1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR1/entry#A0A9J7GBR1-1", "sequence": { "sequence": "MAIQFRSLFPLALPGMLALLGWWWFFSRKKDQLSSNDKQVETLKVGPVIKDQLPSDEACPRVLSMPPSVAQPPETEQLSVGKSSTALPRIRQVRRRSESSGNLPSNVDTRSQPCRDNNSKVELSLMGDEVKSIPLGCPLLPKEVPFPYEAVEGYKQESALGKIPGRGWLDQCAASGEKARETGGAEGTGDAVLGENIPEEGLLSQEYISEVEKSGVPNLAPWGGGGEKMSSGPPQVAELAKKEEFVVGKLPSSFVEPVRSEMVKDEDALVPQVRGGITQDRDLAREQIKEDTLPEKDQIEQAAFQIISRVILEVTEEMGAGKTVVQVYPTSVAQPQGLEESSVPASQETGLGRDIPDPVSTTTGATASPPAEALPPKTYVSCFSSPLSSPTKDQKPKTSAHHISLAPCPLPVTRLRQSLDAASSPGGDDTFVTCMSYNKQSVLSVTSSGQRSHSLTTSGLEDSCTKTISSPGDKAVTPPLPDSTEPFSNGVLKEELSDVGTEDGWTMDAEADHSGAACTIGHLRELKPSQGSDRNSMDSVDSCCGLPKPDSLQNVQASSNPKKVDLIVWEIEVPKHLVGRLIGKQGRYVSFLKQTSGAKIYISTLPYTQNVQICHIEGSQHHVDKALNLIGKKFKELNLTNIYAPPLPSLALPSLPMTSWLMLPDGVTVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSETGLPLIQLWSVVGDEVVLINRSLVERGLAQWVDSYYANL", "length": 862, "header": "tr|A0A9J7GBR1-1|A0A9J7GBR1_CRIGR Isoform 1 of A-kinase anchor protein 1, mitochondrial OS=Cricetulus griseus OX=10029 GN=Akap1 PE=4 SV=1 CANONICAL=A0A9J7GBR1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBK8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBK8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760847", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760847", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR1" } ], "pmid": "" }, { "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 843, "end_pos": 845, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GBR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR1" }, { "id": "PS50304", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tudor", "eco_id": "ECO_0000259", "start_pos": 717, "end_pos": 776, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 843, "end_pos": 845 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GBL1-1", "uniprot_ac": "A0A9J7GBL1", "uniprot_id": "A0A9J7GBL1_CRIGR", "mass": { "chemical_mass": 35288.0, "monoisotopic_mass": 35288.0 }, "refseq": { "ac": "XP_027281960", "name": "olfactory receptor 1468-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281960" }, "gene_names": [ { "name": "LOC113836750", "type": "recommended", "evidence": [ { "id": "A0A9J7GBL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1" } ] }, { "name": "LOC113836750", "type": "synonym", "evidence": [ { "id": "XP_027281960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281960" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7GBL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1468-like", "type": "synonym", "evidence": [ { "id": "XP_027281960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281960" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281960" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113836750", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1", "locus": {} } ], "crossref": [ { "id": "A0A9J7GBL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GBL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113836750", "url": "https://www.ncbi.nlm.nih.gov/gene/113836750", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113836750", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836750", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GBL1", "url": "https://www.orthodb.org/?gene=A0A9J7GBL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281960", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GBL1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEGNQTVISQFLLLGLPIPPEHQHLFYALFLAMNLTTVLGNLIIIILILLDSHLHTPMYFFLSNLSFSDLCFSSVTMPKLLQNMHSLIPSISYAGCLAQLYFYLYFADLESLLLVVMAYDRYVAICFPLHYTSIMSPKLCVGLLVLSWVLTTFHVMLHTLLLARLSFCEDNVIPHFFCDISPLLKLSCSDTHVNELVIFIMGGLFIVIPFLLIIVSYAQIVSSILKVSSVRGIHKVFSTCGSHLSVVSLFYGTIIGLYLCPSANNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKGALARLLCKKKIPFCL", "length": 314, "header": "tr|A0A9J7GBL1-1|A0A9J7GBL1_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC113836750 PE=3 SV=1 CANONICAL=A0A9J7GBL1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1/entry#A0A9J7GBL1-1", "sequence": { "sequence": "MTEGNQTVISQFLLLGLPIPPEHQHLFYALFLAMNLTTVLGNLIIIILILLDSHLHTPMYFFLSNLSFSDLCFSSVTMPKLLQNMHSLIPSISYAGCLAQLYFYLYFADLESLLLVVMAYDRYVAICFPLHYTSIMSPKLCVGLLVLSWVLTTFHVMLHTLLLARLSFCEDNVIPHFFCDISPLLKLSCSDTHVNELVIFIMGGLFIVIPFLLIIVSYAQIVSSILKVSSVRGIHKVFSTCGSHLSVVSLFYGTIIGLYLCPSANNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKGALARLLCKKKIPFCL", "length": 314, "header": "tr|A0A9J7GBL1-1|A0A9J7GBL1_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC113836750 PE=3 SV=1 CANONICAL=A0A9J7GBL1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113836750", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836750", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GBL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 265, "end_pos": 267 }, { "start_pos": 266, "end_pos": 268 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GBL6-1", "uniprot_ac": "A0A9J7GBL6", "uniprot_id": "A0A9J7GBL6_CRIGR", "mass": { "chemical_mass": 136635.0, "monoisotopic_mass": 136635.0 }, "refseq": { "ac": "XP_027277901", "name": "tau-tubulin kinase 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277901" }, "gene_names": [ { "name": "Ttbk2", "type": "recommended", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "name": "Ttbk2", "type": "synonym", "evidence": [ { "id": "XP_027277901", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277901" } ] } ], "protein_names": [ { "name": "non-specific serine/threonine protein kinase", "type": "recommended", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6/entry#names_and_taxonomy" } ] }, { "name": "2.7.11.1", "type": "synonym", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6/entry#names_and_taxonomy" } ] }, { "name": "tau-tubulin kinase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027277901", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277901" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027277901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277901" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ttbk2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6", "locus": {} } ], "crossref": [ { "id": "cd14129", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14129", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769455", "url": "https://www.ncbi.nlm.nih.gov/gene/100769455", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769455", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769455", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GBL6", "url": "https://www.orthodb.org/?gene=A0A9J7GBL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027277901", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027277901", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GBL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9I6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESEPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIPVGVSPDKLPGSLAHARPQEKDVWEEMDINKNKIKLGICKAATEEENSHGHVNGILNAPSLGSPVRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTDKFLETCMEKMQKDSSAGKESVLPALPHKPCVPVVSRTDHIWHYDEEYLPEASKPASANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLKDFRTNEVLGHKTTGSPSDEEPEVLQVLEGSPQDEKMQVGPWTDNHHLKESSGVVLALSAECPATAASEQYTDRLDLQAGAASQFITVTPTSPMEAQAEGPLTAITIPRPSVASTQSTSGSFHYGPQPEKKDLQPLEPTVELYSPRENFSGLVVTEGELPSGGSRMDLGLQIDHIGHDMLPNMRDGDISQDLGPKDLPDHNRLVVKEFENLPGETEEKSILGSDNEDEKLSKGQHCVEISLPGDLVTTERDQSATTEPLDGLKTQNFSVVPNEDKNHEIMKLLAVGTSEISQVIDPHAEGQIGQVAVMQKTKLFKGTDIKSEDLPGHQGDLSTFLHQEGKRDKIVPRNGELYHCVPESEHCPPTRKDMLRSSFVTRHSRIPVLAQEIDSTFESSSAVSAKEKLLQKKAYQPELVKLLVEKRQFKSFLGELSSASDKLIEEKLAAAPVPFSEEEVFTPFSRLAVDSHLSRSAEDGFLSPIISQSRKSKIPRPVSWVSTDQVNSSASLQFLPRPPPGKPPIRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGSQKSRSTPQSKSPGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPHHDQRSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCKPSKNGPKGSGSLHHHSASSKTPPGKSKPASKLSR", "length": 1240, "header": "tr|A0A9J7GBL6-1|A0A9J7GBL6_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Ttbk2 PE=3 SV=1 CANONICAL=A0A9J7GBL6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6/entry#A0A9J7GBL6-1", "sequence": { "sequence": 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"length": 1240, "header": "tr|A0A9J7GBL6-1|A0A9J7GBL6_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Ttbk2 PE=3 SV=1 CANONICAL=A0A9J7GBL6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9I6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6/entry#A0A9J7K9I6-1", "sequence": { "sequence": "MLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESEPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIPVGVSPDKLPGSLAHARPQEKDVWEEMDINKNKIKLGICKAATEEENSHGHVNGILNAPSLGSPVRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTDKFLETCMEKMQKDSSAGKESVLPALPHKPCVPVVSRTDHIWHYDEEYLPEASKPASANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLKDFRTNEVLGHKTTGSPSDEEPEVLQVLEGSPQDEKMQVGPWTDNHHLKESSGVVLALSAECPATAASEQYTDRLDLQAGAASQFITVTPTSPMEAQAEGPLTAITIPRPSVASTQSTSGSFHYGPQPEKKDLQPLEPTVELYSPRENFSGLVVTEGELPSGGSRMDLGLQIDHIGHDMLPNMRDGDISQDLGPKDLPDHNRLVVKEFENLPGETEEKSILGSDNEDEKLSKGQHCVEISLPGDLVTTERDQSATTEPLDGLKTQNFSVVPNEDKNHEIMKLLAVGTSEISQVIDPHAEGQIGQVAVMQKTKLFKGTDIKSEDLPGHQGDLSTFLHQEGKRDKIVPRNGELYHCVPESEHCPPTRKDMLRSSFVTRHSRIPVLAQEIDSTFESSSAVSAKEKLLQKKAYQPELVKLLVEKRQFKSFLGELSSASDKLIEEKLAAAPVPFSEEEVFTPFSRLAVDSHLSRSAEDGFLSPIISQSRKSKIPRPVSWVSTDQVNSSASLQFLPRPPPGKPPIRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGSQKSRSTPQSKSPGSPHNPKTPPKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPHHDQRSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCKPSKNGPKGSGSLHHHSASSKTPPGKSKPASKLSR", "length": 1200, "header": "tr|A0A9J7K9I6-1|A0A9J7K9I6_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Ttbk2 PE=3 SV=1 CANONICAL=A0A9J7GBL6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 652, "start_aa": "Thr", "end_pos": 652, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr652", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769455", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769455", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1062, "end_pos": 1064, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1113, "end_pos": 1115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", 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"A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7GBI2-1", "A0A8C2MB66-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3E2-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7F9C4-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2M7I3-1", "A0A8C2N3I1-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A9J7JQZ1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A3L7I1E7-1", "A0A9J7GBL6-1", 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"A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "A0A9J7JYC5-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7JBH0-1", "A0A9J7FEY2-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G3C1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GFS3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7EVK4-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7H6V8-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7J6H1-1", "A0A3L7HV37-1", 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"A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A8C2ML15-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", "A0A9J7KE81-1", "A0A9J7JPE2-1", "A0A9J7F773-1", "A0A8C2L7R1-1", "A0A8C2LHE9-1", "A0A3L7I870-1", "A0A3L7IB60-1", "A0A3L7IBX6-1", "A0A3L7ID00-1", "A0A3L7IEL5-1", "A0A3L7IER1-1", "A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMC9-1", "A0A8C2LMJ0-1", "A0A9J7JQV6-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "A0A8C2MYH0-1", "A0A8C2MV78-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N4W2-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A9J7F0N6-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F3R3-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7FLY5-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3I1" } ] } ] }, { "uniprot_ac": "A0A8C2N3U2", "gene_name": "Pink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] } ] }, { "uniprot_ac": "A0A8C2N6L4", "gene_name": "Prkg1", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8C2N6L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N6L4" } ] } ] }, { "uniprot_ac": "A0A8C2N756", "gene_name": "Map2k5", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2N756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N756" } ] } ] }, { "uniprot_ac": "A0A8C2N9X1", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2N9X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N9X1" } ] } ] }, { "uniprot_ac": "A0A8C2QDX9", "gene_name": "Csnk1g1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QDX9" } ] } ] }, { "uniprot_ac": "A0A8C2QEB8", "gene_name": "Bub1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QEB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QEB8" } ] } ] }, { "uniprot_ac": "A0A8C2QGY5", "gene_name": "Ttbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QGY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGY5" } ] } ] }, { "uniprot_ac": "A0A8C2QH69", "gene_name": "Sgk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QH69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH69" } ] } ] }, { "uniprot_ac": "A0A8C2QHF9", "gene_name": "Lrrk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] } ] }, { "uniprot_ac": "A0A8C2QHS8", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] } ] }, { "uniprot_ac": "A0A8C2QJ34", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8C2QL63", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] } ] }, { "uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1D2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F1D2", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] } ] }, { "uniprot_ac": "A0A9J7GRB5", "gene_name": "LOC113838167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A9J7GTU0", "gene_name": "LOC100757707", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] } ] }, { "uniprot_ac": "A0A9J7GVC9", "gene_name": "LOC100759146", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] } ] }, { "uniprot_ac": "A0A9J7GX76", "gene_name": "Dapk1", 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} ] }, { "uniprot_ac": "A0A9J7JA07", "gene_name": "LOC100750629", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] } ] }, { "uniprot_ac": "A0A9J7JAB2", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JAB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAB2" } ] } ] }, { "uniprot_ac": "A0A9J7JAM4", "gene_name": "Sik1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JAM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAM4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JAM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAM4" } ] } ] }, { "uniprot_ac": "A0A9J7JB60", "gene_name": "Dclk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JB60" } ] } ] }, { "uniprot_ac": "A0A9J7JBH0", "gene_name": "Srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JBH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] } ] }, { "uniprot_ac": "A0A9J7JDU1", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] } ] }, { "uniprot_ac": "A0A9J7JGG9", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] } ] }, { "uniprot_ac": "A0A9J7JHJ2", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = 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This record is derived from a genomic sequence (NW_003614274.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645423" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccdc40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6", "locus": {} } ], "crossref": [ { "id": "A0A9J7GBM6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GBM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756847", "url": "https://www.ncbi.nlm.nih.gov/gene/100756847", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756847", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756847", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GBM6", "url": "https://www.orthodb.org/?gene=A0A9J7GBM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GBN6", "url": "https://www.orthodb.org/?gene=A0A9J7GBN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JUK1", "url": "https://www.orthodb.org/?gene=A0A9J7JUK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16275", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16275", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16275:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16275:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_007645423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GBM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUK1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUK1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEPKDQADGRSHLDGEQASAEEEKEQQQHAEGREVSSPPMENNGQEVDEGGDATKGPEEDIRAESEGRLEGDMVDDEKVRTEGIAIPEGEVESSGDTTQETELESIRETPQETELESIREFLQETEVESIGKFAPKMRERSSGEDTSELDMEHMDLDAIGEDILDMRLESITGEASPQGEGEPAGENVPGGKLDLPGREERYTFSERDDLSERISSPELASSDVSSWEMTSEDINAFVSEGTGLDFPDTSLGIYEALRRRQVSQLRPLEGLTQRILPVGAPHRFRLSAMGSLASSEMDDLLSDTQEISAQEPARRPPGPREETHIQFREDVQSLSPEEQILIEREASEGSDEADDDSAQLVVLDPDHPLMVRFQEALKSYLNRQIDKMKLDIQELDVATKQSRVQRQELGVNLYGVQQHLARLQMLLEKSHDRHSLAACERRQREEELQNTRALYNKTCATANEERKMLAALQADMESLALHLFYMQNIDQDVRDDILVMKQVVRKTEMEKTRAELEKKKQDLFVDQLTERAHQLEENISLFEAQYLSQNEDTRVLRKAVSEAVTEIDTIAMEKKRILQQWTTSLMGMKHRNEAYRTVLDALRECEHQAKSIDGEIEAYKRSIMKEEEKNEKLARLLNRSETEAMLVQKLTTQCLSKQEALQSEFNTYQLALQDTEEMLNKGSLEHSAVMSELQATRQAVHQEEELRQKMDASILDKLQEHGTSSKITKYYQQLLRKLQKENTNLVTHLSKLDGDIAQATLDITNTNCKVDMHKATLAEMDKEVKRLNDLITNSESEIARRTILIERKQSLINFFNKQLEQMVSVLGGEEAGPLELEIKRLTKLIEENNIGVSDAQLTWLRLQQELVQVTQEREEQLVSLNQLKKDIHIMEQKKLRIENKIEQEKKEQKEIHCHMKDLDKDLTKLNVLMDKNRCNSEQLQQSNQLVETEFVCTLKEAEREAIRMQEKLTQLQEEKATLLNSLLEAEHQLMLWEKKIQLAKEMRASVDSEAGQTEIRAMKAEIHRMKVKHGQLMKQQEKMIHEMEMAVARRETMVMQSQGQSKKDKPVTRTDFHLHQNELRKKIREVHKATEDCGNTISELEETQKLLSSSLQEKQQSLSKMQGDLDVLEGEISQLTSLKRQNLLEIVAMQTRAKNLQAAIDGKYVFLYRNSKTQLQERKKLDIRLVQLNSVLSQIQEDYPQYREVLHKVHQKVSSRLKSPDPS", "length": 1224, "header": "tr|A0A9J7GBM6-1|A0A9J7GBM6_CRIGR Isoform 1 of Coiled-coil domain-containing protein 40 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ccdc40 PE=4 SV=1 CANONICAL=A0A9J7GBM6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6/entry#A0A9J7GBM6-1", "sequence": { "sequence": "MAEPKDQADGRSHLDGEQASAEEEKEQQQHAEGREVSSPPMENNGQEVDEGGDATKGPEEDIRAESEGRLEGDMVDDEKVRTEGIAIPEGEVESSGDTTQETELESIRETPQETELESIREFLQETEVESIGKFAPKMRERSSGEDTSELDMEHMDLDAIGEDILDMRLESITGEASPQGEGEPAGENVPGGKLDLPGREERYTFSERDDLSERISSPELASSDVSSWEMTSEDINAFVSEGTGLDFPDTSLGIYEALRRRQVSQLRPLEGLTQRILPVGAPHRFRLSAMGSLASSEMDDLLSDTQEISAQEPARRPPGPREETHIQFREDVQSLSPEEQILIEREASEGSDEADDDSAQLVVLDPDHPLMVRFQEALKSYLNRQIDKMKLDIQELDVATKQSRVQRQELGVNLYGVQQHLARLQMLLEKSHDRHSLAACERRQREEELQNTRALYNKTCATANEERKMLAALQADMESLALHLFYMQNIDQDVRDDILVMKQVVRKTEMEKTRAELEKKKQDLFVDQLTERAHQLEENISLFEAQYLSQNEDTRVLRKAVSEAVTEIDTIAMEKKRILQQWTTSLMGMKHRNEAYRTVLDALRECEHQAKSIDGEIEAYKRSIMKEEEKNEKLARLLNRSETEAMLVQKLTTQCLSKQEALQSEFNTYQLALQDTEEMLNKGSLEHSAVMSELQATRQAVHQEEELRQKMDASILDKLQEHGTSSKITKYYQQLLRKLQKENTNLVTHLSKLDGDIAQATLDITNTNCKVDMHKATLAEMDKEVKRLNDLITNSESEIARRTILIERKQSLINFFNKQLEQMVSVLGGEEAGPLELEIKRLTKLIEENNIGVSDAQLTWLRLQQELVQVTQEREEQLVSLNQLKKDIHIMEQKKLRIENKIEQEKKEQKEIHCHMKDLDKDLTKLNVLMDKNRCNSEQLQQSNQLVETEFVCTLKEAEREAIRMQEKLTQLQEEKATLLNSLLEAEHQLMLWEKKIQLAKEMRASVDSEAGQTEIRAMKAEIHRMKVKHGQLMKQQEKMIHEMEMAVARRETMVMQSQGQSKKDKPVTRTDFHLHQNELRKKIREVHKATEDCGNTISELEETQKLLSSSLQEKQQSLSKMQGDLDVLEGEISQLTSLKRQNLLEIVAMQTRAKNLQAAIDGKYVFLYRNSKTQLQERKKLDIRLVQLNSVLSQIQEDYPQYREVLHKVHQKVSSRLKSPDPS", "length": 1224, "header": "tr|A0A9J7GBM6-1|A0A9J7GBM6_CRIGR Isoform 1 of Coiled-coil domain-containing protein 40 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ccdc40 PE=4 SV=1 CANONICAL=A0A9J7GBM6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6/entry#A0A9J7GBN6-1", "sequence": { "sequence": "MAEPKDQADGRSHLDGEQASAEEEKEQQQHAEGREVSSPPMENNGQEVDEGGDATKGPEEDIRAESEGRLEGDMVDDEKVRTEGIAIPEGEVESSGDTTQETELESIRETPQETELESIREFLQETEVESIGKFAPKMRERSSGEDTSELDMEHMDLDAIGEDILDMRLESITGEASPQGEGEPAGENVPGGKLDLPGREERYTFSERDDLSERISSPELASSDVSSWEMTSEDINAFVSEGTGLDFPDTSLGIYEALRRRQLRPLEGLTQRILPVGAPHRFRLSAMGSLASSEMDDLLSDTQEISAQEPARRPPGPREETHIQFREDVQSLSPEEQILIEREASEGSDEADDDSAQLVVLDPDHPLMVRFQEALKSYLNRQIDKMKLDIQELDVATKQSRVQRQELGVNLYGVQQHLARLQMLLEKSHDRHSLAACERRQREEELQNTRALYNKTCATANEERKMLAALQADMESLALHLFYMQNIDQDVRDDILVMKQVVRKTEMEKTRAELEKKKQDLFVDQLTERAHQLEENISLFEAQYLSQNEDTRVLRKAVSEAVTEIDTIAMEKKRILQQWTTSLMGMKHRNEAYRTVLDALRECEHQAKSIDGEIEAYKRSIMKEEEKNEKLARLLNRSETEAMLVQKLTTQCLSKQEALQSEFNTYQLALQDTEEMLNKGSLEHSAVMSELQATRQAVHQEEELRQKMDASILDKLQEHGTSSKITKYYQQLLRKLQKENTNLVTHLSKLDGDIAQATLDITNTNCKVDMHKATLAEMDKEVKRLNDLITNSESEIARRTILIERKQSLINFFNKQLEQMVSVLGGEEAGPLELEIKRLTKLIEENNIGVSDAQLTWLRLQQELVQVTQEREEQLVSLNQLKKDIHIMEQKKLRIENKIEQEKKEQKEIHCHMKDLDKDLTKLNVLMDKNRCNSEQLQQSNQLVETEFVCTLKEAEREAIRMQEKLTQLQEEKATLLNSLLEAEHQLMLWEKKIQLAKEMRASVDSEAGQTEIRAMKAEIHRMKVKHGQLMKQQEKMIHEMEMAVARRETMVMQSQGQSKKDKPVTRTDFHLHQNELRKKIREVHKATEDCGNTISELEETQKLLSSSLQEKQQSLSKMQGDLDVLEGEISQLTSLKRQNLLEIVAMQTRAKNLQAAIDGKYVFLYRNSKTQLQERKKLDIRLVQLNSVLSQIQEDYPQYREVLHKVHQKVSSRLKSPDPS", "length": 1221, "header": "tr|A0A9J7GBN6-1|A0A9J7GBN6_CRIGR Computationally mapped isoform of Coiled-coil domain-containing protein 40 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ccdc40 PE=4 SV=1 CANONICAL=A0A9J7GBM6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JUK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6/entry#A0A9J7JUK1-1", "sequence": { "sequence": "MAEPKDQADGSHLDGEQASAEEEKEQQQHAEGREVSSPPMENNGQEVDEGGDATKGPEEDIRAESEGRLEGDMVDDEKVRTEGIAIPEGEVESSGDTTQETELESIRETPQETELESIREFLQETEVESIGKFAPKMRERSSGEDTSELDMEHMDLDAIGEDILDMRLESITGEASPQGEGEPAGENVPGGKLDLPGREERYTFSERDDLSERISSPELASSDVSSWEMTSEDINAFVSEGTGLDFPDTSLGIYEALRRRQVSQLRPLEGLTQRILPVGAPHRFRLSAMGSLASSEMDDLLSDTQEISAQEPARRPPGPREETHIQFREDVQSLSPEEQILIEREASEGSDEADDDSAQLVVLDPDHPLMVRFQEALKSYLNRQIDKMKLDIQELDVATKQSRVQRQELGVNLYGVQQHLARLQMLLEKSHDRHSLAACERRQREEELQNTRALYNKTCATANEERKMLAALQADMESLALHLFYMQNIDQDVRDDILVMKQVVRKTEMEKTRAELEKKKQDLFVDQLTERAHQLEENISLFEAQYLSQNEDTRVLRKAVSEAVTEIDTIAMEKKRILQQWTTSLMGMKHRNEAYRTVLDALRECEHQAKSIDGEIEAYKRSIMKEEEKNEKLARLLNRSETEAMLVQKLTTQCLSKQEALQSEFNTYQLALQDTEEMLNKGSLEHSAVMSELQATRQAVHQEEELRQKMDASILDKLQEHGTSSKITKYYQQLLRKLQKENTNLVTHLSKLDGDIAQATLDITNTNCKVDMHKATLAEMDKEVKRLNDLITNSESEIARRTILIERKQSLINFFNKQLEQMVSVLGGEEAGPLELEIKRLTKLIEENNIGVSDAQLTWLRLQQELVQVTQEREEQLVSLNQLKKDIHIMEQKKLRIENKIEQEKKEQKEIHCHMKDLDKDLTKLNVLMDKNRCNSEQLQQSNQLVETEFVCTLKEAEREAIRMQEKLTQLQEEKATLLNSLLEAEHQLMLWEKKIQLAKEMRASVDSEAGQTEIRAMKAEIHRMKVKHGQLMKQQEKMIHEMEMAVARRETMVMQSQGQSKKDKPVTRTDFHLHQNELRKKIREVHKATEDCGNTISELEETQKLLSSSLQEKQQSLSKMQGDLDVLEGEISQLTSLKRQNLLEIVAMQTRAKNLQAAIDGKYVFLYRNSKTQLQERKKLDIRLVQLNSVLSQIQEDYPQYREVLHKVHQKVSSRLKSPDPS", "length": 1223, "header": "tr|A0A9J7JUK1-1|A0A9J7JUK1_CRIGR Computationally mapped isoform of Coiled-coil domain-containing protein 40 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ccdc40 PE=4 SV=1 CANONICAL=A0A9J7GBM6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756847", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756847", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "heart looping", "id": "GO:0001947", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001947", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6" } ], "pmid": "" }, { "name": "axoneme assembly", "id": "GO:0035082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035082", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6" } ], "pmid": "" }, { "name": "epithelial cilium movement involved in determination of left/right asymmetry", "id": "GO:0060287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060287", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 457, "end_pos": 459 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 639, "end_pos": 641 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GBN9-1", "uniprot_ac": "A0A9J7GBN9", "uniprot_id": "A0A9J7GBN9_CRIGR", "mass": { "chemical_mass": 34407.0, "monoisotopic_mass": 34407.0 }, "refseq": { "ac": "XP_027282021", "name": "olfactory receptor 1361", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282021" }, "gene_names": [ { "name": "LOC100760851", "type": "recommended", "evidence": [ { "id": "A0A9J7GBN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBN9" } ] }, { "name": "LOC100760851", "type": "synonym", "evidence": [ { "id": "XP_027282021", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282021" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7GBN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBN9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1361", "type": "synonym", "evidence": [ { "id": "XP_027282021", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282021" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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"length": 2303, "header": "tr|A0A9J7GBP8-1|A0A9J7GBP8_CRIGR Isoform 1 of Probable G-protein coupled receptor 179 OS=Cricetulus griseus OX=10029 GN=Gpr179 PE=3 SV=1 CANONICAL=A0A9J7GBP8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP8/entry#A0A9J7GBP8-1", "sequence": { "sequence": "MGTRAVVAPSLVWGLLSCFFLCNWALGSQRPFRSLPPLPSQAGPGPGPTWKPPQRAEAALAFLYSGDVQQLSGANCSESYEVRGTEGKVGIPPVLQRAAGTLAQAANFLNMLLQANDIRESSVEEDVEWYQALVRSVAEGDPKAYRALLTFNPPPGASHLPLALQATRMGDETVLQDLSGNRVQEENPEEDLDNPVLQKRVLTNDLRSLDSPKWPRGDGYVGDIQQVKLSAPFLECHEGRFRPGWLVTVSATFYGLKPDLTPEVRGQVQMDIDLQNVDINQCASGPGWYSNTHLCDLNSTQCVPLESQGFVLGRYLCRCRPGFYEASGSGGLEESATQTAGQFGSPQGSLGKLMRCQPCPEGCSSCLDATPCLAEEALALRAIVLACQACFMLTVFLSMLVAYRCRGSKRIRASGIFLLETILFGSLLLYFPVFILYFKPSVFRCIALRWVRLLGFAVVYGTIILKLYRVLQLFLSRTAQRGPHPSSGQLLRRLGQLLLLVLGFLVVWTAGVLEPGIQHTPLVTRGHTPTGRHFYLCHHDHWDYVMVVAEMLLLCWGSFLCYATRAVPSAFHEPRYMSIAIHNELLLSTVFHTARFVLVPSLHPDWTLLLFFLHTHSTVTATLALIFIPKFWKPGAPPREEILDEVYEDELDLQRSGSYLNSSIASAWSERSLDPGDIRDELKKLYAQLEVRKTKEMTANNPHLPKKQSSSHQGLGRSFMRYLAEFPEALARQHSRDSGSPSRSSQPGSSRRRLLSSSLQETEKPPALRKTRSTYDHHRKHNTPLLDSTLRRTLSKKASTAEGQVEGPPALGFRSASAHNLTVGERLPGARPMSLQKSLSVVAGSREKALLVASQAYLEETYRQAKEREERKKAEAAIVSPVRRPSARRLERPLRAPLSAPPSPAKSSSMDSSHTPGRPHEEAGRMLPHPPIRHQVSTPILALSGACLGEPRMLSPTPTSTLAPILLPALAPTPTPALAPVPMPPQSPTLLTFICPWENAELPGKKEKVVQEVPTGSEQSSHSSASARTKIWRALSVAVEKRGTGESERTSEDGHVQGGDDHGEEDKPKAFSKSHSLKTPLQQGSVRSLGLAIKALARSRSTYKEKEGGEGSSETEKEKPIGVSMGAPPPSPRLGRPKAVSKQAALTPCEDEESLQNQQNVHTSRMLHVFHKEGSRGQEDRNKRASQGLGELRVERTGKIGLATLRQAFGDKNTEQAKESSVGDQEVTATALQPLGSADHRVAEVCPWEVTQSGMCQPESNNKAKICSWEGNEGGLEKTLSRQVPSSSWEEREKAPEESEPEGVGAITRKKPERLVRSQEAVCPWESADTGGLSPQLAHRDSDRTQGRSVVVGGTEVRKGERPTEVLPPEAKAELCPWELSDAGEGTLAQRVKGLPEERQKSPKKATVWREQNLGRDLVSLCPWESTDFRGPSAVSLQAPESSGNLGSGIAEVCPWEIGETSNDKKAEVCPWELGAGTETLNHGRDGESLPGKETTSRKQYLGAMGEQESVCPWEDASPGQSSPHPNNSSKAGGQLLSSGGSQALQVCPWEAFKPEEKQATPSMAEICPWEADGRTKDRTSEPTPKGEELQKEEKIPGKARIQTWEKAEGQTQKQEAICPWESMGPSSILQKDTEKLQVTLQRRGSIGGKAAEICPWDVEERLTAEKAKICPWEVGAGAGEERTMGGAEASGISPNDTGQTSAESGPRQIAATTPKKTERPGLEEVVCSWGSLGPGDSSQQPDILSTEKPKDGLQELDHVGSRPTEVCPWEVEEVPISEKAKICPWEVNEGTMVKGLEQELGIKPAEQEPKNLEKAEQEEGTSKGDAKLCQEQEAICPWKDQDSRKPSAPVPKVSDLPSSISSQRSEVQSLEDSDRATEKGGLRQDLKTSSFPEHTTQGKAAALKSQFPVDGGGTSKELQSVCPWESMVPASSSLHPQGQCSDQPRAGSQVSPGSGVAEVPVSDQYEVCPWKATGRIMETQTSGQGKMEESQEEKEGAPEKPKQKGALVQKTPQTSNFGKQEAVCPRGSQDFGIQPATGASDVNKSSSEKVGCVGVRMVKVWPWETEEGPSAKKAEICPWEASPGAVGEGTRDQGQDGKSQGDEQAEGHFLEVAEAVYPSEGAASAGLFPCTLDTDTLDHPKASPQGASSPGKRLAVLCQWEVTDPEGNKIKGTMADICPWEEPRAPSDESGFLALPTTQTDVPATPEKSLCLSAHRPLESFLPQSKSQHPEVTKPPSAFPLESVKEQGPTGLEPGTKSAPEPSLKDAEAPKSFSLIEDQGQMAPEAQDEEFSPPPAYPWDCE", "length": 2303, "header": "tr|A0A9J7GBP8-1|A0A9J7GBP8_CRIGR Isoform 1 of Probable G-protein coupled receptor 179 OS=Cricetulus griseus OX=10029 GN=Gpr179 PE=3 SV=1 CANONICAL=A0A9J7GBP8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 49, "start_aa": "Thr", "end_pos": 49, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr49", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 957, "start_aa": "Thr", "end_pos": 957, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr957", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 973, "start_aa": "Thr", "end_pos": 973, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr973", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 975, "start_aa": "Thr", "end_pos": 975, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr975", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763472", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763472", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP8" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1527, "end_pos": 1529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1528, "end_pos": 1530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1696, "end_pos": 1698, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2044, "end_pos": 2046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 661, "end_pos": 663, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": 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"sequon_annotation_sites": [ { "start_pos": 1527, "end_pos": 1529 }, { "start_pos": 1528, "end_pos": 1530 }, { "start_pos": 1696, "end_pos": 1698 }, { "start_pos": 2044, "end_pos": 2046 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 661, "end_pos": 663 }, { "start_pos": 75, "end_pos": 77 }, { "start_pos": 820, "end_pos": 822 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", 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"uniprot_canonical_ac": "A0A9J7GBQ0-1", "uniprot_ac": "A0A9J7GBQ0", "uniprot_id": "A0A9J7GBQ0_CRIGR", "mass": { "chemical_mass": 24331.0, "monoisotopic_mass": 24331.0 }, "refseq": { "ac": "XP_003498114", "name": "protein Mis18-beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498114" }, "gene_names": [ { "name": "Oip5", "type": "recommended", "evidence": [ { "id": "A0A9J7GBQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0" } ] }, { "name": "Oip5", "type": "synonym", "evidence": [ { "id": "XP_003498114", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498114" } ] } ], "protein_names": [ { "name": "Protein Mis18-beta", "type": "synonym", "evidence": [ { "id": "A0A9J7GBQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0/entry#names_and_taxonomy" } ] }, { "name": "protein Mis18-beta", "type": "synonym", "evidence": [ { "id": "XP_003498114", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498114" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498114" } ] }, { "annotation": "Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0#function" }, { "database": "UniProtKB", "id": "ARBA00003694", "url": "https://www.uniprot.org/uniprotkb/ARBA00003694#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Oip5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0", "locus": {} } ], "crossref": [ { "id": "A0A9J7GBQ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GBQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100763649", "url": "https://www.ncbi.nlm.nih.gov/gene/100763649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763649", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763649", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GBQ0", "url": "https://www.orthodb.org/?gene=A0A9J7GBQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16431:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16431:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003498114", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498114", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GBQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMARSRRLLPSPESPCCSDSCDTPSAATSMEWDTQVVSGSSPLGPPETEVETSPVDLRLPAWLEPERCAVFHCAHCHAVLADTVHLAWDLSRSLGTVAFSRVTNNVVLLEPCLVGIEGSLKCSTYNLLFCNSCGVPVGFHLYSTHAALAALRGHFCLSCDKMVCYLLKTKEIVSASEMDIHNVPLPEKIAELKEKIMLMHARLNSLIKILKDVTPDHSNQEN", "length": 222, "header": "tr|A0A9J7GBQ0-1|A0A9J7GBQ0_CRIGR Isoform 1 of Protein Mis18-beta OS=Cricetulus griseus OX=10029 GN=Oip5 PE=4 SV=1 CANONICAL=A0A9J7GBQ0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0/entry#A0A9J7GBQ0-1", "sequence": { "sequence": "MMARSRRLLPSPESPCCSDSCDTPSAATSMEWDTQVVSGSSPLGPPETEVETSPVDLRLPAWLEPERCAVFHCAHCHAVLADTVHLAWDLSRSLGTVAFSRVTNNVVLLEPCLVGIEGSLKCSTYNLLFCNSCGVPVGFHLYSTHAALAALRGHFCLSCDKMVCYLLKTKEIVSASEMDIHNVPLPEKIAELKEKIMLMHARLNSLIKILKDVTPDHSNQEN", "length": 222, "header": "tr|A0A9J7GBQ0-1|A0A9J7GBQ0_CRIGR Isoform 1 of Protein Mis18-beta OS=Cricetulus griseus OX=10029 GN=Oip5 PE=4 SV=1 CANONICAL=A0A9J7GBQ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"database": "UniProtKB", "id": "A0A9J7GBQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GBQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ0" }, { "id": "PS51793", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51793" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mis18", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 167, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GBQ4-1", "uniprot_ac": "A0A9J7GBQ4", "uniprot_id": "A0A9J7GBQ4_CRIGR", "mass": { "chemical_mass": 62151.0, "monoisotopic_mass": 62151.0 }, "refseq": { "ac": "XP_027282065", "name": "syntaxin-binding protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282065" }, "gene_names": [ { "name": "Stxbp4", "type": "recommended", "evidence": [ { "id": "A0A9J7GBQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ4" } ] }, { "name": "Stxbp4", "type": "synonym", "evidence": [ { "id": "XP_027282065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282065" } ] } ], "protein_names": [ { "name": "Syntaxin-binding protein 4", "type": "recommended", "evidence": [ { "id": "A0A9J7GBQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ4/entry#names_and_taxonomy" } ] }, { "name": "Syntaxin 4-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A9J7GBQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ4/entry#names_and_taxonomy" } ] }, { "name": "syntaxin-binding protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027282065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282065" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282065" } ] }, { "annotation": "Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBQ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ4#function" }, { "database": "UniProtKB", "id": "ARBA00053815", "url": "https://www.uniprot.org/uniprotkb/ARBA00053815#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBQ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Stxbp4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ4", "locus": {} } ], "crossref": [ { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06698", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06698", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100758822", "url": "https://www.ncbi.nlm.nih.gov/gene/100758822", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758822", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758822", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GBQ4", "url": "https://www.orthodb.org/?gene=A0A9J7GBQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19964:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19964:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282065", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GBQ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3V2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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MODEL REFSEQ: This record is predicted by automated computational analysis. 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"A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061HZS8", "gene_name": "Ptpn14", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HZS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZS8" } ] } ] }, { "uniprot_ac": "A0A061IAM9", "gene_name": "LOC100766206", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] } ] }, { "uniprot_ac": "A0A3L7HAL2", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7I231", "gene_name": "Ptp4a3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] } ] }, { "uniprot_ac": "A0A3L7IA07", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] } ] }, { "uniprot_ac": "A0A8C2LH05", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", 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{ "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] } ] }, { "uniprot_ac": "A0A8C2MFV5", "gene_name": "LOC100758361", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] } ] }, { "uniprot_ac": "A0A8C2MQ28", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] } ] }, { "uniprot_ac": "A0A8C2MZ43", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": 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"evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EXY7", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] } ] }, { "uniprot_ac": "A0A9J7FEZ5", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] } ] }, { "uniprot_ac": "A0A9J7FG56", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] } ] }, { "uniprot_ac": "A0A9J7FIV0", "gene_name": "LOC100763249", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FWX7", "gene_name": "LOC103158664", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] } ] }, { "uniprot_ac": "A0A9J7FYL8", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] } ] }, { "uniprot_ac": "A0A9J7G003", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G003", "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] } ] }, { "uniprot_ac": "A0A9J7G7K2", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] } ] }, { "uniprot_ac": "A0A9J7G7L1", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] } ] }, { "uniprot_ac": "A0A9J7GBQ5", "gene_name": "LOC100764354", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GNR2", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] } ] }, { "uniprot_ac": "A0A9J7GQC8", "gene_name": "LOC100757114", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] } ] }, { "uniprot_ac": "A0A9J7GQG9", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] } ] }, { "uniprot_ac": "A0A9J7GX92", "gene_name": "Ptpre", 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771256", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771256", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR2" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR2" } ], "pmid": "" }, { "name": "globoside alpha-N-acetylgalactosaminyltransferase activity", "id": "GO:0047277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047277", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBR2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBR2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "A0A9J7JW92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW92#function" }, { "id": "A0A9J7JW92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW92" }, { "id": "PIRSR605076-3", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR605076-3" } ], "binding_site_uniprot": 104, "amino_acid": "Gln", "chebi_lig_id": "CHEBI_29035", 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GBS7-1", "uniprot_ac": "A0A9J7GBS7", "uniprot_id": "A0A9J7GBS7_CRIGR", "mass": { "chemical_mass": 54544.0, "monoisotopic_mass": 54544.0 }, "refseq": { "ac": "XP_007641177", "name": "LOW QUALITY PROTEIN: fibroblast growth factor receptor-like 1 isoform X1", "summary": "", "url": 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel assembly gap :: added 342 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613892.1) and transcript sequence (IACG01100200.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007641177.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007641177", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641177" } ] }, { "annotation": "Has a negative effect on cell proliferation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBS7#function" }, { "database": "UniProtKB", "id": "ARBA00053149", "url": "https://www.uniprot.org/uniprotkb/ARBA00053149#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBS7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fgfrl1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBS7", "locus": {} } ], "crossref": [ { "id": "A0A9J7GBS7", 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19890:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007641177", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007641177", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTRSPALLLLLLLPPLLLGALPSAEAARGPPRMADKVAPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLKVKEVEAEDAGVYVCKATNGFGSLSVNYTLIIMDDVNPGKESPGPGGSSGGQEDPANQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDIMWMKDDQTLTRPEASEHRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSLQCKVRSDVKPVIQWLKRVEYGSEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLISRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPLVAPSSSTTSLPWPVVIGIPAGAVFILGTVLLWLCQAKKKPCAPASALPVPGHRPPGASRDRGGDKDLSSLAVGLCEEHGSTMAPQHVLASGSTAGPKLYPKLYTDVHTHTHTHTCTHTFRVEGKVHRPQHVHCQC", "length": 502, "header": "tr|A0A9J7GBS7-1|A0A9J7GBS7_CRIGR Isoform 1 of Fibroblast growth factor receptor-like 1 OS=Cricetulus griseus OX=10029 GN=Fgfrl1 PE=4 SV=1 CANONICAL=A0A9J7GBS7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBS7/entry#A0A9J7GBS7-1", "sequence": { "sequence": "MTRSPALLLLLLLPPLLLGALPSAEAARGPPRMADKVAPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLKVKEVEAEDAGVYVCKATNGFGSLSVNYTLIIMDDVNPGKESPGPGGSSGGQEDPANQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDIMWMKDDQTLTRPEASEHRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSLQCKVRSDVKPVIQWLKRVEYGSEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLISRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPLVAPSSSTTSLPWPVVIGIPAGAVFILGTVLLWLCQAKKKPCAPASALPVPGHRPPGASRDRGGDKDLSSLAVGLCEEHGSTMAPQHVLASGSTAGPKLYPKLYTDVHTHTHTHTCTHTFRVEGKVHRPQHVHCQC", "length": 502, "header": "tr|A0A9J7GBS7-1|A0A9J7GBS7_CRIGR Isoform 1 of Fibroblast growth factor receptor-like 1 OS=Cricetulus griseus OX=10029 GN=Fgfrl1 PE=4 SV=1 CANONICAL=A0A9J7GBS7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"database": "UniProtKB", "id": "A0A9J7GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBS7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GBS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBS7" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 117, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 295, "end_pos": 297 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GBV5-1", "uniprot_ac": "A0A9J7GBV5", "uniprot_id": "A0A9J7GBV5_CRIGR", "mass": { "chemical_mass": 121383.0, "monoisotopic_mass": 121383.0 }, "refseq": { "ac": "XP_027278086", "name": "anoctamin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278086" }, "gene_names": [ { "name": "Ano3", "type": "recommended", "evidence": [ { "id": "A0A9J7GBV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBV5" } ] }, { "name": "Ano3", "type": "synonym", "evidence": [ { "id": "XP_027278086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278086" } ] } ], "protein_names": [ { "name": "Anoctamin", "type": "recommended", "evidence": [ { "id": "A0A9J7GBV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBV5/entry#names_and_taxonomy" } ] }, { "name": "anoctamin-3", "type": "synonym", "evidence": [ { "id": "XP_027278086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278086" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027278086.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278086" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBV5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ano3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBV5", "locus": {} } ], "crossref": [ { "id": "A0A9J7GBV5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GBV5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100760607", "url": "https://www.ncbi.nlm.nih.gov/gene/100760607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760607", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760607", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GBV5", "url": "https://www.orthodb.org/?gene=A0A9J7GBV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12308:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12308:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04547", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04547", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278086", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GBV5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBV5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1041, "header": "tr|A0A9J7GBV5-1|A0A9J7GBV5_CRIGR Isoform 1 of Anoctamin OS=Cricetulus griseus OX=10029 GN=Ano3 PE=3 SV=1 CANONICAL=A0A9J7GBV5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBV5/entry#A0A9J7GBV5-1", "sequence": { "sequence": 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"authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GBX5-1", "uniprot_ac": "A0A9J7GBX5", "uniprot_id": "A0A9J7GBX5_CRIGR", "mass": { "chemical_mass": 319465.0, "monoisotopic_mass": 319465.0 }, "refseq": { "ac": "XP_027282333", "name": "neurofibromin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282333" }, "gene_names": [ { "name": "LOC100770202", "type": "recommended", "evidence": [ { "id": "A0A9J7GBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5" } ] }, { "name": "LOC100770202", "type": "synonym", "evidence": [ { "id": "XP_027282333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282333" } ] } ], "protein_names": [ { "name": "Neurofibromin", "type": "recommended", "evidence": [ { "id": "A0A9J7GBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5/entry#names_and_taxonomy" } ] }, { "name": "Neurofibromatosis-related protein NF-1", "type": "synonym", "evidence": [ { "id": "A0A9J7GBX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5/entry#names_and_taxonomy" } ] }, { "name": "neurofibromin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027282333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282333" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282333" } ] }, { "annotation": "Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5#function" }, { "database": "UniProtKB", "id": "ARBA00059799", "url": "https://www.uniprot.org/uniprotkb/ARBA00059799#function" }, { "database": "UniProtKB", "id": "A0A9J7GET5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GET5#function" }, { "database": "UniProtKB", "id": "A0A9J7JYL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYL6#function" }, { "database": "UniProtKB", "id": "A0A9J7H300", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H300#function" }, { "database": "UniProtKB", "id": "A0A9J7H760", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H760#function" }, { "database": "UniProtKB", "id": "A0A9J7GGJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGJ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", 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"MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNINKKLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKQADRSSCHFLFLCGVGCDVPASGNATQMSMDHDELLRTCTPGASLRKGKGNSSMDSTAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNVDTPVSRFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDSNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLESSESLEENQRNLLQMTEKFFHAIISSSLEFPSQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHRALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPILHGDPSYRTLKENQPWSSPKGSEGYLAATYPSVGQTSPRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRISSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEEASEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV", "length": 2840, "header": "tr|A0A9J7GBX5-1|A0A9J7GBX5_CRIGR Isoform 1 of Neurofibromin OS=Cricetulus griseus OX=10029 GN=LOC100770202 PE=4 SV=1 CANONICAL=A0A9J7GBX5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GBX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5/entry#A0A9J7GBX5-1", "sequence": { "sequence": "MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNINKKLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKQADRSSCHFLFLCGVGCDVPASGNATQMSMDHDELLRTCTPGASLRKGKGNSSMDSTAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNVDTPVSRFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDSNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLESSESLEENQRNLLQMTEKFFHAIISSSLEFPSQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHRALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPILHGDPSYRTLKENQPWSSPKGSEGYLAATYPSVGQTSPRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRISSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEEASEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV", "length": 2840, "header": "tr|A0A9J7GBX5-1|A0A9J7GBX5_CRIGR Isoform 1 of Neurofibromin OS=Cricetulus griseus OX=10029 GN=LOC100770202 PE=4 SV=1 CANONICAL=A0A9J7GBX5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GET5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5/entry#A0A9J7GET5-1", "sequence": { "sequence": "MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNINKKLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKQADRSSCHFLFLCGVGCDVPASGNATQMSMDHDELLRTCTPGASLRKGKGNSSMDSTAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNVDTPVSRFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDSNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLESSESLEENQRNLLQMTEKFFHAIISSSLEFPSQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHRALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPILHGDPSYRTLKENQPWSSPKGSEGYLAATYPSVGQTSPRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRISSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKESTRRTLNSPPPLATVTVDELAMDPQARCRSKEALAVSNVIALRRSCEAFFLSLFKPT", "length": 2779, "header": "tr|A0A9J7GET5-1|A0A9J7GET5_CRIGR Computationally mapped isoform of Neurofibromin OS=Cricetulus griseus OX=10029 GN=LOC100770202 PE=4 SV=1 CANONICAL=A0A9J7GBX5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5/entry#A0A9J7GEW7-1", "sequence": { "sequence": "MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNINKKLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKQADRSSCHFLFLCGVGCDVPASGNATQMSMDHDELLRTCTPGASLRKGKGNSSMDSTAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNVDTPVSRFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDSNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLESSESLEENQRNLLQMTEKFFHAIISSSLEFPSQLRSVCHCLYQATCHSLLNKATVKEKKENKKSIVVPNG", "length": 1399, "header": "tr|A0A9J7GEW7-1|A0A9J7GEW7_CRIGR Computationally mapped isoform of Neurofibromin isoform X8 OS=Cricetulus griseus OX=10029 GN=LOC100770202 PE=4 SV=1 CANONICAL=A0A9J7GBX5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GGJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5/entry#A0A9J7GGJ9-1", "sequence": { "sequence": "MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNINKKLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKADRSSCHFLFLCGVGCDVPASGNATQMSMDHDELLRTCTPGASLRKGKGNSSMDSTAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNVDTPVSRFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDSNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLESSESLEENQRNLLQMTEKFFHAIISSSLEFPSQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHRALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPILHGDPSYRTLKENQPWSSPKGSEGYLAATYPSVGQTSPRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRISSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEEASEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV", "length": 2839, "header": "tr|A0A9J7GGJ9-1|A0A9J7GGJ9_CRIGR Computationally mapped isoform of Neurofibromin OS=Cricetulus griseus OX=10029 GN=LOC100770202 PE=4 SV=1 CANONICAL=A0A9J7GBX5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H300-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5/entry#A0A9J7H300-1", "sequence": { "sequence": "MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNINKKLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKQADRSSCHFLFLCGVGCDVPASGNATQMSMDHDELLRTCTPGASLRKGKGNSSMDSTAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNVDTPVSRFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDSNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLESSESLEENQRNLLQMTEKFFHAIISSSLEFPSQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKILQSIANHVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHRALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPILHGDPSYRTLKENQPWSSPKGSEGYLAATYPSVGQTSPRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRISSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEEASEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV", "length": 2836, "header": "tr|A0A9J7H300-1|A0A9J7H300_CRIGR Computationally mapped isoform of Neurofibromin OS=Cricetulus griseus OX=10029 GN=LOC100770202 PE=4 SV=1 CANONICAL=A0A9J7GBX5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H760-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5/entry#A0A9J7H760-1", "sequence": { "sequence": "MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNINKKLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKQADRSSCHFLFLCGVGCDVPASGNATQMSMDHDELLRTCTPGASLRKGKGNSSMDSTAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNVDTPVSRFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDSNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLESSESLEENQRNLLQMTEKFFHAIISSSLEFPSQLRSVCHCLYQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHRALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPILHGDPSYRTLKENQPWSSPKGSEGYLAATYPSVGQTSPRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRISSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEEASEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV", "length": 2801, "header": "tr|A0A9J7H760-1|A0A9J7H760_CRIGR Computationally mapped isoform of Neurofibromin OS=Cricetulus griseus OX=10029 GN=LOC100770202 PE=4 SV=1 CANONICAL=A0A9J7GBX5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5/entry#A0A9J7JYL6-1", "sequence": { "sequence": "MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHFLHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNINKKLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNPSKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITNSALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWLREILICRNKFLLKNKQADRSSCHFLFLCGVGCDVPASGNATQMSMDHDELLRTCTPGASLRKGKGNSSMDSTAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINMTGFLCALGGVCLQQRSSSGLATYSPPMGPVSERKGSMISVMSSEGNVDTPVSRFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDSNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVSFEVDPTRLESSESLEENQRNLLQMTEKFFHAIISSSLEFPSQLRSVCHCLYQVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDLARRFFLDIASDCPTSDAVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHRALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKSLLLTDISMENVPMDTYPILHGDPSYRTLKENQPWSSPKGSEGYLAATYPSVGQTSPRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEMETQRISSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEEASEESLLTPTSPYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQVQKQRSAGSFKRNSIKKIV", "length": 2819, "header": "tr|A0A9J7JYL6-1|A0A9J7JYL6_CRIGR Computationally mapped isoform of Neurofibromin OS=Cricetulus griseus OX=10029 GN=LOC100770202 PE=4 SV=1 CANONICAL=A0A9J7GBX5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2068, "start_aa": "Thr", "end_pos": 2068, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2068", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770202", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770202", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of developmental process", "id": "GO:0050793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050793", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBX5" } ], "pmid": "" }, { "name": "Schwann cell differentiation", "id": "GO:0014037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014037", "evidence": [ { "database": 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This record is derived from a genomic sequence (NW_003613601.1) and transcript sequence (IACG01068485.1) annotated using gene prediction method: Gnomon. 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"MAFFNTQAPYVNPPIPFSGIIHGGLQEGLQITIHGTVHASANKITVNFQTGLNENDIAFHFNPRFEDGGYVVCNTKQKGNWGPEERKMQMPFQKGRPFELTFLVQRSEFKVMVNKNFFVQYSHRVPYHLVDTIAVSGSLQLSFITFQSSPAVPVQPVFSTVQFSQPIQFPRNPRGHKPKSVRPVHQAPVAQTVIHTVHTAPGPMLPTPGIQPVVYPTTVYPAPFLTSIPNGLYPSKSIIIAGIVLPNAKRFHINLRSGMDVAFHLNPRFNENVVVRNTQINNTWGPEERNLVGKMPFSCGQSFSVWILCESHCFKVSVDGQHLCDYVHRLKHLPGINNLEVAGDVQLTHVQA", "length": 352, "header": "tr|A0A9J7GD15-1|A0A9J7GD15_CRIGR Isoform 1 of Galectin OS=Cricetulus griseus OX=10029 GN=Lgals9 PE=4 SV=1 CANONICAL=A0A9J7GD15-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 207, "start_aa": "Thr", "end_pos": 207, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr207", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278172" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBZ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBZ7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pdhx", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBZ7", "locus": {} } ], "crossref": [ { "id": "A0A9J7GBZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GBZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06849", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06849", "database": "CDD", "categories": [ "Protein Classification" ] }, 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GBZ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBZ7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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hybrid assembly strategy.", "journal": "Biotechnol. 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"MADGGSERADGRIVKMEVDYSATVDQRLPECEKLAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPVKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISSDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGVELRKGSPETPATDVFSATEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGVINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ", "length": 456, "header": "tr|A0A9J7GC45-1|A0A9J7GC45_CRIGR Isoform 1 of 26S proteasome non-ATPase regulatory subunit 12 OS=Cricetulus griseus OX=10029 GN=Psmd12 PE=3 SV=1 CANONICAL=A0A9J7GC45-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GC45-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC45/entry#A0A9J7GC45-1", "sequence": { "sequence": 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GC46-1", "uniprot_ac": "A0A9J7GC46", "uniprot_id": "A0A9J7GC46_CRIGR", "mass": { "chemical_mass": 18427.0, "monoisotopic_mass": 18427.0 }, "refseq": { "ac": "XP_016818767", "name": "60S ribosomal protein L23a isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818767" }, "gene_names": [ { "name": "Rpl23a", "type": "recommended", "evidence": [ { "id": "A0A9J7GC46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC46" } ] }, { "name": "Rpl23a", "type": "synonym", "evidence": [ { "id": "XP_016818767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818767" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein uL23", "type": "recommended", "evidence": [ { "id": "A0A9J7GC46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC46/entry#names_and_taxonomy" } ] }, { "name": "60S ribosomal protein L23a isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016818767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818767" } ] }, { "name": "60S ribosomal protein L23a", "type": "synonym", "evidence": [ { "id": "A0A9J7GC46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC46/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616155.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016818767", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818767" } ] }, { "annotation": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC46#function" }, { "database": "UniProtKB", "id": "ARBA00045456", "url": "https://www.uniprot.org/uniprotkb/ARBA00045456#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC46" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rpl23a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC46", "locus": {} } ], "crossref": [ { "id": "A0A9J7GC46", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GC46", "database": "AlphaFoldDB", "categories": [] }, { "id": "100761992", "url": "https://www.ncbi.nlm.nih.gov/gene/100761992", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005633", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005633", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019985", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019985", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761992", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761992", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GC46", "url": "https://www.orthodb.org/?gene=A0A9J7GC46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11620", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11620", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00276", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00276", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03939", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03939", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016818767", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818767", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GC46", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPKAKKEVTFPSLSAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "length": 163, "header": "tr|A0A9J7GC46-1|A0A9J7GC46_CRIGR Isoform 1 of Large ribosomal subunit protein uL23 OS=Cricetulus griseus OX=10029 GN=Rpl23a PE=3 SV=1 CANONICAL=A0A9J7GC46-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GC46-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC46/entry#A0A9J7GC46-1", "sequence": { "sequence": "MAPKAKKEVTFPSLSAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII", "length": 163, "header": "tr|A0A9J7GC46-1|A0A9J7GC46_CRIGR Isoform 1 of Large ribosomal subunit protein uL23 OS=Cricetulus griseus OX=10029 GN=Rpl23a PE=3 SV=1 CANONICAL=A0A9J7GC46-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0047372", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC62" } ], "pmid": "" }, { "name": "short-chain carboxylesterase activity", "id": "GO:0034338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034338", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GC67-1", "uniprot_ac": "A0A9J7GC67", "uniprot_id": "A0A9J7GC67_CRIGR", "mass": { "chemical_mass": 197925.0, "monoisotopic_mass": 197925.0 }, "refseq": { "ac": "XP_027281702", "name": "BTB/POZ domain-containing protein 8 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281702" }, "gene_names": [ { "name": "Btbd8", "type": "recommended", "evidence": [ { "id": "A0A9J7GC67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67" } ] }, { "name": "Btbd8", "type": "synonym", "evidence": [ { "id": "XP_027281702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281702" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein 8", "type": "recommended", "evidence": [ { "id": "A0A9J7GC67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67/entry#names_and_taxonomy" } ] }, { "name": "AP2-interacting clathrin-endocytosis protein", "type": "synonym", "evidence": [ { "id": "A0A9J7GC67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67/entry#names_and_taxonomy" } ] }, { "name": "BTB/POZ domain-containing protein 8 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027281702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281702" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281702" } ] }, { "annotation": "Involved in clathrin-mediated endocytosis at the synapse. Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67#function" }, { "database": "UniProtKB", "id": "ARBA00058836", "url": "https://www.uniprot.org/uniprotkb/ARBA00058836#function" }, { "database": "UniProtKB", "id": "A0A9J7JP21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP21#function" }, { "database": "UniProtKB", "id": "A0A9J7JY50", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY50#function" }, { "database": "UniProtKB", "id": "A0A9J7H3Z2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Z2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Btbd8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67", "locus": {} } ], "crossref": [ { "id": "cd18285", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18285", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18286", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18286", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18490", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18490", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769097", "url": "https://www.ncbi.nlm.nih.gov/gene/100769097", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769097", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769097", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GC67", "url": "https://www.orthodb.org/?gene=A0A9J7GC67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22427:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22427:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281702", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GC67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3Z2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP21-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JY50", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JY50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JY50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAAPGPRVCGSLSAAFRVRLQTRRGWTGTFLLGAGSAARQCERERPLPGPAGPAGAQGSVADYGSLCGGRRDPRGASGVPGAGRKGLSRKGPGERRRLKTMVSEQLSRDVLRLLREEIHTDTVLSVGGSLFKVHRAVLLARAPGFHFHVLGQMSSGLTNEPVPVDSVDASEFRTFLQIVYSSNNSIKNYEEEIVKKMKVESVILEKKATVSFQECRNLSGCFPGKSDIPADITGRDVSFISSDNYHLEPASELGEDLLKLYVNQCCPDIDICVDGKNFRAHRAILSARSGYFAAMLSGCWAESSQECVTLQGITHAEMNVVMHFIYGGTLDFPDKANVGQILNVADMYGLEGLREVAVYILRRDYCNFFQKPVPRTLSSILECLIIAHSVGVESLFADCMNWIISHFARFWSERSFANVPHELQKTCLRMLIQSLNHRNAALLLMESDRLIMGLPRVKWTEAALSMASQLQEECVAFIVENFSKTIETENFTLLLQSQAMSSTAHLLDKIFKAIEDNITTENSCSLLMALDTLLNSESTKEMGFTCKIQAVRDKLWTFLVQSFYAVRHTESWGQMHIGDQQKIQAAAFDKGDNRRLGRKPVLTSSQPRRQGSDADIIKKKPWMENNKNLYRKYLSINQNMKSDGLGASGHTSITNRNSVNKALKHNDSTKISRVTKELKTGGGNISGKSKAVIKAQTENNDNTKLEDLSKAAGGPAKTAATGQKDSVLGKGVRNREAQTTGARPKALGANLNVQARAKPLKTGTRKDSPCPTTVGPAGRSTNLSMELLTSTGHEDEPKENGSVEDRSPGEKPHFSDSPGEVLNDGVSAVAVKSRPVSRVINGASHKKSTHERDSNISSSVIKKVSGKGLSDPAPHAAVKKRVSSNGYTAAQPRTKSAPPTLAQIQGCHGESPHSVKSSGSSRQSHENVTKLRHSAAADKQTPKRKIVKQGHGTLQKVNAKVVSSPKDTSQSKKGGVLNNANSKQKVLPGEVTTQTQASQRPSKTEAATTQKCILPNVNDKNHVFKQRPPGSLVQLASETSGAGTLQSLCRPHPQKPLDSHRKKKPELECQKSSNPDESIKHELKSKQTGLGQSNTSSYKDTNHCSANSNHSNITALKYTVSNPNENSTNSNPVCDSNTANAERVRLFSDREKQTGKKNTDTKPSMNCVKAKEASPCVPEGTGGTLNSFQDERKSSVQSQLPDNSATKDNKCASVNSAVSSKCLLGQPSGKNDKNMETSETPEGHETPEAPFIGHWDLSTSATHQRESPESDTASATTSSDDIKPRSEDYDAGGSQDDEGSNDRGISKCGTMLCPDFLGRSSSDTSTPEELKGYDTNLRIEVKVKKQGDLFQINSTSDDEIPRKKPEIWSRSTIIHPRERENTTRGSVSFAQEMDQVSSSADETEDERSEAENTGENSSPCNSGTQHIQGIVNLAFEDGTEHESREFSAPKRFRRSVLLSVDECEEVGSDEGEGHAPLQPSVDSPSPSYIFHGVSYEHHGRTGYSRLLKESEDATVHCKHNDKGNSVYKNESVLLGPSSKDFSRKDKQSVSTAQKNRLDVPPKGSQQLSPEDEEINSRSKVANGFQQHNTFLDGDTKSQERPCHLELHQRELSSNIPKMSSAKSLDSYLSQVPPQEGQGKESHSTSPKKANNAVFSGDIDDCDTLAQTCMYDHRPSKTLSPIYETDIAEAFEQKVESEIHVIDRDSEDGQHFAKQDWTLLRQLLSEQDANLNVTHSLPEDLSLAQYLIKQTLLLAGDSSKPQGSAHADSWNRWSELSSPLDGSWTSDTTAGVPSEGCSPLGEWTILELETQH", "length": 1812, "header": "tr|A0A9J7GC67-1|A0A9J7GC67_CRIGR Isoform 1 of BTB/POZ domain-containing protein 8 OS=Cricetulus griseus OX=10029 GN=Btbd8 PE=4 SV=1 CANONICAL=A0A9J7GC67-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GC67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67/entry#A0A9J7GC67-1", "sequence": { "sequence": "MRAAPGPRVCGSLSAAFRVRLQTRRGWTGTFLLGAGSAARQCERERPLPGPAGPAGAQGSVADYGSLCGGRRDPRGASGVPGAGRKGLSRKGPGERRRLKTMVSEQLSRDVLRLLREEIHTDTVLSVGGSLFKVHRAVLLARAPGFHFHVLGQMSSGLTNEPVPVDSVDASEFRTFLQIVYSSNNSIKNYEEEIVKKMKVESVILEKKATVSFQECRNLSGCFPGKSDIPADITGRDVSFISSDNYHLEPASELGEDLLKLYVNQCCPDIDICVDGKNFRAHRAILSARSGYFAAMLSGCWAESSQECVTLQGITHAEMNVVMHFIYGGTLDFPDKANVGQILNVADMYGLEGLREVAVYILRRDYCNFFQKPVPRTLSSILECLIIAHSVGVESLFADCMNWIISHFARFWSERSFANVPHELQKTCLRMLIQSLNHRNAALLLMESDRLIMGLPRVKWTEAALSMASQLQEECVAFIVENFSKTIETENFTLLLQSQAMSSTAHLLDKIFKAIEDNITTENSCSLLMALDTLLNSESTKEMGFTCKIQAVRDKLWTFLVQSFYAVRHTESWGQMHIGDQQKIQAAAFDKGDNRRLGRKPVLTSSQPRRQGSDADIIKKKPWMENNKNLYRKYLSINQNMKSDGLGASGHTSITNRNSVNKALKHNDSTKISRVTKELKTGGGNISGKSKAVIKAQTENNDNTKLEDLSKAAGGPAKTAATGQKDSVLGKGVRNREAQTTGARPKALGANLNVQARAKPLKTGTRKDSPCPTTVGPAGRSTNLSMELLTSTGHEDEPKENGSVEDRSPGEKPHFSDSPGEVLNDGVSAVAVKSRPVSRVINGASHKKSTHERDSNISSSVIKKVSGKGLSDPAPHAAVKKRVSSNGYTAAQPRTKSAPPTLAQIQGCHGESPHSVKSSGSSRQSHENVTKLRHSAAADKQTPKRKIVKQGHGTLQKVNAKVVSSPKDTSQSKKGGVLNNANSKQKVLPGEVTTQTQASQRPSKTEAATTQKCILPNVNDKNHVFKQRPPGSLVQLASETSGAGTLQSLCRPHPQKPLDSHRKKKPELECQKSSNPDESIKHELKSKQTGLGQSNTSSYKDTNHCSANSNHSNITALKYTVSNPNENSTNSNPVCDSNTANAERVRLFSDREKQTGKKNTDTKPSMNCVKAKEASPCVPEGTGGTLNSFQDERKSSVQSQLPDNSATKDNKCASVNSAVSSKCLLGQPSGKNDKNMETSETPEGHETPEAPFIGHWDLSTSATHQRESPESDTASATTSSDDIKPRSEDYDAGGSQDDEGSNDRGISKCGTMLCPDFLGRSSSDTSTPEELKGYDTNLRIEVKVKKQGDLFQINSTSDDEIPRKKPEIWSRSTIIHPRERENTTRGSVSFAQEMDQVSSSADETEDERSEAENTGENSSPCNSGTQHIQGIVNLAFEDGTEHESREFSAPKRFRRSVLLSVDECEEVGSDEGEGHAPLQPSVDSPSPSYIFHGVSYEHHGRTGYSRLLKESEDATVHCKHNDKGNSVYKNESVLLGPSSKDFSRKDKQSVSTAQKNRLDVPPKGSQQLSPEDEEINSRSKVANGFQQHNTFLDGDTKSQERPCHLELHQRELSSNIPKMSSAKSLDSYLSQVPPQEGQGKESHSTSPKKANNAVFSGDIDDCDTLAQTCMYDHRPSKTLSPIYETDIAEAFEQKVESEIHVIDRDSEDGQHFAKQDWTLLRQLLSEQDANLNVTHSLPEDLSLAQYLIKQTLLLAGDSSKPQGSAHADSWNRWSELSSPLDGSWTSDTTAGVPSEGCSPLGEWTILELETQH", "length": 1812, "header": "tr|A0A9J7GC67-1|A0A9J7GC67_CRIGR Isoform 1 of BTB/POZ domain-containing protein 8 OS=Cricetulus griseus OX=10029 GN=Btbd8 PE=4 SV=1 CANONICAL=A0A9J7GC67-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67/entry#A0A9J7H3Z2-1", "sequence": { "sequence": "MLQSLEHFYNNYHLEPASELGEDLLKLYVNQCCPDIDICVDGKNFRAHRAILSARSGYFAAMLSGCWAESSQECVTLQGITHAEMNVVMHFIYGGTLDFPDKANVGQILNVADMYGLEGLREVAVYILRRDYCNFFQKPVPRTLSSILECLIIAHSVGVESLFADCMNWIISHFARFWSERSFANVPHELQKTCLRMLIQSLNHRNAALLLMESDRLIMGLPRVKWTEAALSMASQLQEECVAFIVENFSKTIETENFTLLLQSQAMSSTAHLLDKIFKAIEDNITTENSCSLLMALDTLLNSESTKEMGFTCKIQAVRDKLWTFLVQSFYAVRHTESWGQMHIGDQQKIQAAAFDKGDNRRLGRKPVLTSSQPRRQGSDADIIKKKPWMENNKNLYRKYLSINQNMKSDGLGASGHTSITNRNSVNKALKHNDSTKISRVTKELKTGGGNISGKSKAVIKAQTENNDNTKLEDLSKAAGGPAKTAATGQKDSVLGKGVRNREAQTTGARPKALGANLNVQARAKPLKTGTRKDSPCPTTVGPAGRSTNLSMELLTSTGHEDEPKENGSVEDRSPGEKPHFSDSPGEVLNDGVSAVAVKSRPVSRVINGASHKKSTHERDSNISSSVIKKVSGKGLSDPAPHAAVKKRVSSNGYTAAQPRTKSAPPTLAQIQGCHGESPHSVKSSGSSRQSHENVTKLRHSAAADKQTPKRKIVKQGHGTLQKVNAKVVSSPKDTSQSKKGGVLNNANSKQKVLPGEVTTQTQASQRPSKTEAATTQKCILPNVNDKNHVFKQRPPGSLVQLASETSGAGTLQSLCRPHPQKPLDSHRKKKPELECQKSSNPDESIKHELKSKQTGLGQSNTSSYKDTNHCSANSNHSNITALKYTVSNPNENSTNSNPVCDSNTANAERVRLFSDREKQTGKKNTDTKPSMNCVKAKEASPCVPEGTGGTLNSFQDERKSSVQSQLPDNSATKDNKCASVNSAVSSKCLLGQPSGKNDKNMETSETPEGHETPEAPFIGHWDLSTSATHQRESPESDTASATTSSDDIKPRSEDYDAGGSQDDEGSNDRGISKCGTMLCPDFLGRSSSDTSTPEELKGYDTNLRIEVKVKKQGDLFQINSTSDDEIPRKKPEIWSRSTIIHPRERENTTRGSVSFAQEMDQVSSSADETEDERSEAENTGENSSPCNSGTQHIQGIVNLAFEDGTEHESREFSAPKRFRRSVLLSVDECEEVGSDEGEGHAPLQPSVDSPSPSYIFHGVSYEHHGRTGYSRLLKESEDATVHCKHNDKGNSVYKNESVLLGPSSKDFSRKDKQSVSTAQKNRLDVPPKGSQQLSPEDEEINSRSKVANGFQQHNTFLDGDTKSQERPCHLELHQRELSSNIPKMSSAKSLDSYLSQVPPQEGQGKESHSTSPKKANNAVFSGDIDDCDTLAQTCMYDHRPSKTLSPIYETDIAEAFEQKVESEIHVIDRDSEDGQHFAKQDWTLLRQLLSEQDANLNVTHSLPEDLSLAQYLIKQTLLLAGDSSKPQGSAHADSWNRWSELSSPLDGSWTSDTTAGVPSEGCSPLGEWTILELETQH", "length": 1578, "header": "tr|A0A9J7H3Z2-1|A0A9J7H3Z2_CRIGR Computationally mapped isoform of BTB/POZ domain-containing protein 8 OS=Cricetulus griseus OX=10029 GN=Btbd8 PE=4 SV=1 CANONICAL=A0A9J7GC67-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JP21-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67/entry#A0A9J7JP21-1", "sequence": { "sequence": 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"length": 1702, "header": "tr|A0A9J7JP21-1|A0A9J7JP21_CRIGR Computationally mapped isoform of BTB/POZ domain-containing protein 8 OS=Cricetulus griseus OX=10029 GN=Btbd8 PE=4 SV=1 CANONICAL=A0A9J7GC67-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JY50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67/entry#A0A9J7JY50-1", "sequence": { "sequence": "MRAAPGPRVCGSLSAAFRVRLQTRRGWTGTFLLGAGSAARQCERERPLPGPAGPAGAQGSVADYGSLCGGRRDPRGASGVPGAGRKGLSRKGPGERRRLKTMVSEQLSRDVLRLLREEIHTDTVLSVGGSLFKVHRAVLLARAPGFHFHVLGQMSSGLTNEPVPVDSVDASEFRTFLQIVYSSNNSIKNYEEEIVKKMKVESVILEKKATVSFQECRNLSGCFPGKSDIPADITGRDVSFISSDNYHLEPASELGEDLLKLYVNQCCPDIDICVDGKNFRAHRAILSARSGYFAAMLSGCWAESSQECVTLQGITHAEMNVVMHFIYGGTLDFPDKANVGQILNVADMYGLEGLREVAVYILRRDYCNFFQKPVPRTLSSILECLIIAHSVGVESLFADCMNWIISHFARFWSERSFANVPHELQKTCLRMLIQSLNHRNAALLLMESDRLIMGLPRVKWTEAALSMASQLQEECVAFIVENFSKTIETENFTLLLQGFTCKIQAVRDKLWTFLVQSFYAVRHTESWGQMHIGDQQKIQAAAFDKGDNRRLGRKPVLTSSQPRRQGSDADIIKKKPWMENNKNLYRKYLSINQNMKSDGLGASGHTSITNRNSVNKALKHNDSTKISRVTKELKTGGGNISGKSKAVIKAQTENNDNTKLEDLSKAAGGPAKTAATGQKDSVLGKGVRNREAQTTGARPKALGANLNVQARAKPLKTGTRKDSPCPTTVGPAGRSTNLSMELLTSTGHEDEPKENGSVEDRSPGEKPHFSDSPGEVLNDGVSAVAVKSRPVSRVINGASHKKSTHERDSNISSSVIKKVSGKGLSDPAPHAAVKKRVSSNGYTAAQPRTKSAPPTLAQIQGCHGESPHSVKSSGSSRQSHENVTKLRHSAAADKQTPKRKIVKQGHGTLQKVNAKVVSSPKDTSQSKKGGVLNNANSKQKVLPGEVTTQTQASQRPSKTEAATTQKCILPNVNDKNHVFKQRPPGSLVQLASETSGAGTLQSLCRPHPQKPLDSHRKKKPELECQKSSNPDESIKHELKSKQTGLGQSNTSSYKDTNHCSANSNHSNITALKYTVSNPNENSTNSNPVCDSNTANAERVRLFSDREKQTGKKNTDTKPSMNCVKAKEASPCVPEGTGGTLNSFQDERKSSVQSQLPDNSATKDNKCASVNSAVSSKCLLGQPSGKNDKNMETSETPEGHETPEAPFIGHWDLSTSATHQRESPESDTASATTSSDDIKPRSEDYDAGGSQDDEGSNDRGISKCGTMLCPDFLGRSSSDTSTPEELKGYDTNLRIEVKVKKQGDLFQINSTSDDEIPRKKPEIWSRSTIIHPRERENTTRGSVSFAQEMDQVSSSADETEDERSEAENTGENSSPCNSGTQHIQGIVNLAFEDGTEHESREFSAPKRFRRSVLLSVDECEEVGSDEGEGHAPLQPSVDSPSPSYIFHGVSYEHHGRTGYSRLLKESEDATVHCKHNDKGNSVYKNESVLLGPSSKDFSRKDKQSVSTAQKNRLDVPPKGSQQLSPEDEEINSRSKVANGFQQHNTFLDGDTKSQERPCHLELHQRELSSNIPKMSSAKSLDSYLSQVPPQEGQGKESHSTSPKKANNAVFSGDIDDCDTLAQTCMYDHRPSKTLSPIYETDIAEAFEQKVESEIHVIDRDSEDGQHFAKQDWTLLRQLLSEQDANLNVTHSLPEDLSLAQYLIKQTLLLAGDSSKPQGSAHADSWNRWSELSSPLDGSWTSDTTAGVPSEGCSPLGEWTILELETQH", "length": 1766, "header": "tr|A0A9J7JY50-1|A0A9J7JY50_CRIGR Computationally mapped isoform of BTB/POZ domain-containing protein 8 OS=Cricetulus griseus OX=10029 GN=Btbd8 PE=4 SV=1 CANONICAL=A0A9J7GC67-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769097", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "clathrin-coated vesicle", "id": "GO:0030136", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030136", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1095, "end_pos": 1097, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1110, "end_pos": 1112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1113, "end_pos": 1115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1127, "end_pos": 1129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1354, "end_pos": 1356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1382, "end_pos": 1384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1417, "end_pos": 1419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1530, "end_pos": 1532, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1732, "end_pos": 1734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 856, "end_pos": 858, "annotation": "n_glycosylation_sequon" }, { "start_pos": 928, "end_pos": 930, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GC67", "database": "UniProtKB", "url": 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"end_pos": 1734 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 667, "end_pos": 669 }, { "start_pos": 685, "end_pos": 687 }, { "start_pos": 783, "end_pos": 785 }, { "start_pos": 801, "end_pos": 803 }, { "start_pos": 856, "end_pos": 858 }, { "start_pos": 928, "end_pos": 930 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GCB7-1", "uniprot_ac": "A0A9J7GCB7", "uniprot_id": "A0A9J7GCB7_CRIGR", "mass": { "chemical_mass": 150958.0, "monoisotopic_mass": 150958.0 }, "refseq": { "ac": "XP_027282585", "name": "clustered mitochondria protein homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282585" }, "gene_names": [ { "name": "Cluh", "type": "recommended", "evidence": [ { "id": "A0A9J7GCB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7" } ] }, { "name": "Cluh", "type": "synonym", "evidence": [ { "id": "XP_027282585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282585" } ] } ], "protein_names": [ { "name": "Clustered mitochondria protein homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7GCB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7/entry#names_and_taxonomy" } ] }, { "name": "clustered mitochondria protein homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027282585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282585" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282585" } ] }, { "annotation": "mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC86#function" }, { "database": "HAMAP", "id": "MF_03013", "url": "https://hamap.expasy.org/signature/MF_03013" }, { "database": "UniProtKB", "id": "A0A9J7GCB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cluh", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7", "locus": {} } ], "crossref": [ { "id": "cd15466", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15466", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766235", "url": "https://www.ncbi.nlm.nih.gov/gene/100766235", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766235", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766235", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCB7", "url": "https://www.orthodb.org/?gene=A0A9J7GCB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12601:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12601:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13424", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13424", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15044", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15044", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282585", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GC86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVIKTDELPAAAPADSAREHGSQAGGKGRPSAAEPPSVMLLNGDCSESLKKEEGTAELPKENGLDEGEPGDETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSLDPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVSITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVLQKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGDVAAYVAPSNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEELPEECTRAGFPRAHRHKLCCLRQELVDAFVEHRYLLFMKLAALQLMQQKANKETPSSLENGGPPSSAEADSEDSVGPEAGSEEEGSSVSGLAKVKELAETIASDDGTVDPRSREVIRNACKAVGSISSTAFDIRFNPDIFSPGVRFPESCQDEVQDQKQLLKDAAAFLLSCQIPGLVKDCTEHAVLPMDGATLAEVMRQRGINMRYLGKVLDLVLRSPARDQLDHIYKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLPADELLSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICQEAKNYFDFTLECDSVDQAVETYGLQKITLLREISLKTGIQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVTTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTRESSEYLKCLTQQAVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEASRNRDKADDVATDPEPARAQQEDMGSPQTAKEDPSLSVQG", "length": 1348, "header": "tr|A0A9J7GCB7-1|A0A9J7GCB7_CRIGR Isoform 1 of Clustered mitochondria protein homolog OS=Cricetulus griseus OX=10029 GN=Cluh PE=3 SV=1 CANONICAL=A0A9J7GCB7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GC86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7/entry#A0A9J7GC86-1", "sequence": { "sequence": 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"length": 1347, "header": "tr|A0A9J7GC86-1|A0A9J7GCB7_CRIGR Computationally mapped isoform of Clustered mitochondria protein homolog OS=Cricetulus griseus OX=10029 GN=Cluh PE=3 SV=1 CANONICAL=A0A9J7GCB7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7/entry#A0A9J7GCB7-1", "sequence": { "sequence": "MVIKTDELPAAAPADSAREHGSQAGGKGRPSAAEPPSVMLLNGDCSESLKKEEGTAELPKENGLDEGEPGDETTGQEVIVIQDTGFSVKILAPGIEPFSLQVSPQEMVQEIHQVLMDREDTCHRTCFSLHLDGNMLDHFSELRSVEGLQEGSVLRVVEEPYTVREARIHVRHVRDLLKSLDPSDAFNGVDCNSLSFLSVFTDGDLGDSGKRKKGLEMDPIDCTPPEYILPGSRERPLCPLQPQNRDWKPLQCLKVLTMSGWNPPPGNRKMHGDLMYLFVITAEDRQVSITASTRGFYLNQSTAYHFNPKPASPRFLSHSLVELLNQISPTFKKNFAVLQKKRVQRHPFERIATPFQVYSWTAPQAEHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELPRKNLPERLLRERAIFKVHSDFTAAATRGAMAVIDGNVMAINPSEETKMQMFIWNNIFFSLGFDVRDHYKDFGGDVAAYVAPSNDLNGVRTYNAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILERDQEQSVIYGSIDFGKTVVSHPRYLELLERTSRPLKILRHRVLNDRDEEVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVPGEELPEECTRAGFPRAHRHKLCCLRQELVDAFVEHRYLLFMKLAALQLMQQKANKETPSSLENGGPPSSAEADSEDSVGPEAGSEEEGSSVSGLAKVKELAETIASDDGTVDPRSREVIRNACKAVGSISSTAFDIRFNPDIFSPGVRFPESCQDEVQDQKQLLKDAAAFLLSCQIPGLVKDCTEHAVLPMDGATLAEVMRQRGINMRYLGKVLDLVLRSPARDQLDHIYKIGIGELITRSAKHIFKTYLQGVELSGLSAAISHFLNCFLSSYPNPVAHLPADELLSKKRNKRRKNRPPGAADNTAWAVMTPQELWKNICQEAKNYFDFTLECDSVDQAVETYGLQKITLLREISLKTGIQILLKEYSFDSRHKPAFTEEDVLNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAVTTKYHGPKALKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKTQLGEDHEKTRESSEYLKCLTQQAVALQRTMNEIYRNGSSANIPPLKFTAPSMASVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEASRNRDKADDVATDPEPARAQQEDMGSPQTAKEDPSLSVQG", "length": 1348, "header": "tr|A0A9J7GCB7-1|A0A9J7GCB7_CRIGR Isoform 1 of Clustered mitochondria protein homolog OS=Cricetulus griseus OX=10029 GN=Cluh PE=3 SV=1 CANONICAL=A0A9J7GCB7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC86" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC86" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766235", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766235", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7" } ], "pmid": "" }, { "name": "intracellular distribution of mitochondria", "id": "GO:0048312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048312", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1253, "end_pos": 1255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GCB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB7" }, { "id": "PS51823", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51823" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Clu", "eco_id": "ECO_0000259", "start_pos": 373, "end_pos": 615, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1253, "end_pos": 1255 }, { "start_pos": 299, "end_pos": 301 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GC92-1", "uniprot_ac": "A0A9J7GC92", "uniprot_id": "A0A9J7GC92_CRIGR", "mass": { "chemical_mass": 16033.0, "monoisotopic_mass": 16033.0 }, "refseq": { "ac": "XP_016831806", "name": "spindle and kinetochore-associated protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831806" }, "gene_names": [ { "name": "Ska2", "type": "recommended", "evidence": [ { "id": "A0A9J7GC92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" } ] }, { "name": "Ska2", "type": "synonym", "evidence": [ { "id": "XP_016831806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831806" } ] } ], "protein_names": [ { "name": "Protein FAM33A", "type": "recommended", "evidence": [ { "id": "A0A9J7GC92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92/entry#names_and_taxonomy" } ] }, { "name": "spindle and kinetochore-associated protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016831806", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831806" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614004.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016831806", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831806" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ska2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92", "locus": {} } ], "crossref": [ { "id": "A0A9J7GC92", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GC92", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12955", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12955", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755178", "url": "https://www.ncbi.nlm.nih.gov/gene/100755178", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755178", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755178", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GC92", "url": "https://www.orthodb.org/?gene=A0A9J7GC92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32017", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32017", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32017:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32017:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16740", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16740", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016831806", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831806", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GC92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWLERSLRAPRRRRELLHVSPPGAMEDEFQKADSDLDYIQYRLEYEIKTNHPDSAGEKNAVAILKELSAIKSRYQALCARFKPLSIEQKENKSRICATLSKTMTTIQELQKQTDLELTQLTEEEKAVTEQLKSHMPDL", "length": 138, "header": "tr|A0A9J7GC92-1|A0A9J7GC92_CRIGR Isoform 1 of Protein FAM33A OS=Cricetulus griseus OX=10029 GN=Ska2 PE=3 SV=1 CANONICAL=A0A9J7GC92-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GC92-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92/entry#A0A9J7GC92-1", "sequence": { "sequence": "MWLERSLRAPRRRRELLHVSPPGAMEDEFQKADSDLDYIQYRLEYEIKTNHPDSAGEKNAVAILKELSAIKSRYQALCARFKPLSIEQKENKSRICATLSKTMTTIQELQKQTDLELTQLTEEEKAVTEQLKSHMPDL", "length": 138, "header": "tr|A0A9J7GC92-1|A0A9J7GC92_CRIGR Isoform 1 of Protein FAM33A OS=Cricetulus griseus OX=10029 GN=Ska2 PE=3 SV=1 CANONICAL=A0A9J7GC92-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755178", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755178", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "mitotic cell cycle", "id": "GO:0000278", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000278", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" } ], "pmid": "" }, { "name": "chromosome segregation", "id": "GO:0007059", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007059", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "spindle microtubule", "id": "GO:0005876", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005876", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" } ], "pmid": "" }, { "name": "outer kinetochore", "id": "GO:0000940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000940", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GC92", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GC92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GC92" }, { "id": "PF16740", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16740" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ska2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 132, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GCB4-1", "uniprot_ac": "A0A9J7GCB4", "uniprot_id": "A0A9J7GCB4_CRIGR", "mass": { "chemical_mass": 129982.0, "monoisotopic_mass": 129982.0 }, "refseq": { "ac": "XP_027281863", "name": "cysteine-rich motor neuron 1 protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281863" }, "gene_names": [ { "name": "Crim1", "type": "recommended", "evidence": [ { "id": "A0A9J7GCB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB4" } ] }, { "name": "Crim1", "type": "synonym", "evidence": [ { "id": "XP_027281863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281863" } ] } ], "protein_names": [ { "name": "Cysteine-rich motor neuron 1 protein", "type": "recommended", "evidence": [ { "id": "A0A9J7GCB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB4/entry#names_and_taxonomy" } ] }, { "name": "cysteine-rich motor neuron 1 protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027281863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281863" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the amino end.", "evidence": [ { "database": "RefSeq", "id": "XP_027281863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281863" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Crim1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB4", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCB4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100765449", "url": "https://www.ncbi.nlm.nih.gov/gene/100765449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052624", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052624", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765449", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765449", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCB4", "url": "https://www.orthodb.org/?gene=A0A9J7GCB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46439", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46439", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46439:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46439:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00219", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00219", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19442", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19442", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23334", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23334", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281863", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PGVQEQSGGPEGATSPAPERSGEERSGAQSSRRRQKFGLNRSCREETFFPLFPLPPGRRRRRRRRRRRGSHPPPLPLAPTLVGSGSARPAGAAGASPREGRSAPGAPRGHEDRGLRVRRRRRVCPRRGGRPPRSRPGCEEEAAAAQEDVLGGGGRGLAGCGHLSVSLLGLLLLLARSGTRALVCLPCDESKCEEPRSCPGSIVQGVCGCCYMCARQRNESCGGAYGLHGACDRGLRCVIRPPLNGDSITEYEVGVCEDEDWDEDQLLGFEPCNENLISGCNIINGKCECDTIRTCNNPFEFPRKDMCLSALKRIEEEKPDCSKARCEVQFSPRCPEDSVLIEGYAPPGECCPLPSRCVCDPAGCLRKVCQPGYLNILVSKASGKPGECCDLYECKPVFSVDCSTVECPPVQQAVCPLDSYETQVRLTADGCCTLPARCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNETKPACVFNSVEYYDGDMFRMDNCRFCRCQGGVSICFTAQCGELNCERYYVPEGECCPVCEDPIYPFNNPAGCYANGQIRAHGDRWREDDCTFCQCINGEPHCVATACGQSCMHPVKVPGECCPVCEEPTYITIDPPACGELSNCTLKEKDCIYGFKLDHNGCRTCQCKNREELCLGLKRGCTLDCPFGFLTDAHNCELCQCRPRPKKCKPTMCGKFCPLGFLKNKHGCDICRCKKCPELPCSKICPLGFQQDSHGCLICKCREVPPSAGPPVLSGTCLSMDGHHHKNEESWHDGCRECYCHNGREMCALITCPVPACGNPTIRPGQCCPSCADDFVVQKPELSTPSICHAPGGEYFVEGETWNIDSCTQCTCHGGRVLCETEVCPPLLCQSPSRTQDSCCPQCTDEPLQPSTSHNESVPSYCKNDEGDIFLAAESWKPDVCTSCVCMDSVISCYSESCPSVSCERPVLRKGQCCPYCLEDTISKKVVCHFSGKTYADEERWDIDSCTHCYCLQGQTLCSTVSCPPLPCAEPIKVEGSCCPMCPEMYVPEPTNVPIEKKNHRGEIDLEAPMWPTPSENDIIHLPRDMGHLQVDYRDSSRLHPSEDSSLDSIVSVVVPIIICLSIIIAFLLINQKKQWVPLLCWYRTPTKPSSLNNQLVSVDCKKGTRVQARDGSQTMLRIAEPDARFSGFYSMQKQNHLQADNFYQTV", 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This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027278432.1. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCB5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755477", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755477", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCB5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCB5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCB5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GCB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCB5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 290, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDG4-1", "uniprot_ac": "A0A9J7GDG4", "uniprot_id": "A0A9J7GDG4_CRIGR", "mass": { "chemical_mass": 135160.0, "monoisotopic_mass": 135160.0 }, "refseq": { "ac": "XP_027282694", "name": "calmodulin-binding transcription activator 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282694" }, "gene_names": [ { "name": "Camta2", "type": "recommended", "evidence": [ { "id": "A0A9J7GDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4" } ] }, { "name": "Camta2", "type": "synonym", "evidence": [ { "id": "XP_027282694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282694" } ] } ], "protein_names": [ { "name": "Calmodulin-binding transcription activator 2", "type": "recommended", "evidence": [ { "id": "A0A9J7GDG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4/entry#names_and_taxonomy" } ] }, { "name": "calmodulin-binding transcription activator 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027282694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282694" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282694" } ] }, { "annotation": "Transcription activator. May act as tumor suppressor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCD2#function" }, { "database": "UniProtKB", "id": "ARBA00057661", "url": "https://www.uniprot.org/uniprotkb/ARBA00057661#function" }, { "database": "UniProtKB", "id": "A0A9J7GCF7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCF7#function" }, { "database": "UniProtKB", "id": "A0A9J7GDG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4#function" }, { "database": "UniProtKB", "id": "A0A9J7H7N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7N5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Camta2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4", "locus": {} } ], "crossref": [ { "id": "A0A9J7GDG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GDG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100772126", "url": "https://www.ncbi.nlm.nih.gov/gene/100772126", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772126", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772126", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDG4", "url": "https://www.orthodb.org/?gene=A0A9J7GDG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23335", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23335", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23335:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23335:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03859", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03859", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282694", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCF7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7N5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7N5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAVTRGTPGDSPSPRPLRPGVTLPPGTLTMNTKDTTEVAENSHHLKIFLPKKLLECLPRCALLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMEPVSWQCLYGCYVHSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHGIKWSCGNGAEEFSVEQLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLASISHSQPPEPPPLITPLPPELPKAHTSPSSSSSSSSSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQAEPRPVSLAVVVGSEPSALPTPPSPAFDPDRFLNSPQRGQTYGGGQGVNPDFPEAEGTHTPCPALEPAAALEPQAAARGLPSQLGASGRRGNQFFIQDDDSGEELKGQETVPPVPSPPPSSPSSPATLQPSGRVTRGEALFGGSGGTSELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALNTITDFSPEWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDSQFRMSILERLEQMEKRMAEIAAAGQAPGQSPEAPPIQDEGQGPGFEARVVVLVESMIPRSTWRGPERLIHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFCWNRQALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEHPLALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAADGSPPPVPLLASEITMEMIPGQLSPGATETPLLLMDYEATRSKESVPSLSGPPLAQKDGTPPEDAGSPPAVDVIPVDMISLAKQIIEATPERIKREDFSGLPEAGASLREQTGTVGLSETMSWLASYLENVDHFPSSAPTSELPFERGRLAIPPTPSWAEFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPAHRPSGPLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGLAT", "length": 1238, "header": "tr|A0A9J7GDG4-1|A0A9J7GDG4_CRIGR Isoform 1 of Calmodulin-binding transcription activator 2 OS=Cricetulus griseus OX=10029 GN=Camta2 PE=3 SV=1 CANONICAL=A0A9J7GDG4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4/entry#A0A9J7GCD2-1", "sequence": { "sequence": "MAAAAVTRGTPGDSPSPRPLRPGVTLPPGTLTMNTKDTTEVAENSHHLKIFLPKKLLECLPRCALLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMENPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHGIKWSCGNGAEEFSVEQLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLASISHSQPPEPPPLITPLPPELPKAHTSPSSSSSSSSSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQAEPRPVSLAVVVGSEPSALPTPPSPAFDPDRFLNSPQRGQTYGGGQGVNPDFPEAEGTHTPCPALEPAAALEPQAAARGLPSQLGASGRRGNQFFIQDDDSGEELKGQETVPPVPSPPPSSPSSPATLQPSGRVTRGEALFGGSGGTSELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALNTITDFSPEWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDSQFRMSILERLEQMEKRMAEIAAAGQAPGQSPEAPPIQDEGQGPGFEARVVVLVESMIPRSTWRGPERLIHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFCWNRQALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEHPLALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAADGSPPPVPLLASEITMEMIPGQLSPGATETPLLLMDYEATRSKESVPSLSGPPLAQKDGTPPEDAGSPPAVDVIPVDMISLAKQIIEATPERIKREDFSGLPEAGASLREQTGTVGLSETMSWLASYLENVDHFPSSAPTSELPFERGRLAIPPTPSWAEFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPAHRPSGPLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGLAT", "length": 1209, "header": "tr|A0A9J7GCD2-1|A0A9J7GDG4_CRIGR Computationally mapped isoform of Calmodulin-binding transcription activator 2 OS=Cricetulus griseus OX=10029 GN=Camta2 PE=3 SV=1 CANONICAL=A0A9J7GDG4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4/entry#A0A9J7GCF7-1", "sequence": { "sequence": "MAAAAVTRGTPGDSPSPRPLRPGVTLPPGTLTMNTKDTTEVAENSHHLKIFLPKKLLECLPRCALLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMECLYGCYVHSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHGIKWSCGNGAEEFSVEQLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLASISHSQPPEPPPLITPLPPELPKAHTSPSSSSSSSSSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQAEPRPVSLAVVVGSEPSALPTPPSPAFDPDRFLNSPQRGQTYGGGQGVNPDFPEAEGTHTPCPALEPAAALEPQAAARGLPSQLGASGRRGNQFFIQDDDSGEELKGQETVPPVPSPPPSSPSSPATLQPSGRVTRGEALFGGSGGTSELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALNTITDFSPEWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDSQFRMSILERLEQMEKRMAEIAAAGQAPGQSPEAPPIQDEGQGPGFEARVVVLVESMIPRSTWRGPERLIHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFCWNRQALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEHPLALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAADGSPPPVPLLASEITMEMIPGQLSPGATETPLLLMDYEATRSKESVPSLSGPPLAQKDGTPPEDAGSPPAVDVIPVDMISLAKQIIEATPERIKREDFSGLPEAGASLREQTGTVGLSETMSWLASYLENVDHFPSSAPTSELPFERGRLAIPPTPSWAEFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPAHRPSGPLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGLAT", "length": 1233, "header": "tr|A0A9J7GCF7-1|A0A9J7GCF7_CRIGR Computationally mapped isoform of Calmodulin-binding transcription activator 2 OS=Cricetulus griseus OX=10029 GN=Camta2 PE=3 SV=1 CANONICAL=A0A9J7GDG4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4/entry#A0A9J7GDG4-1", "sequence": { "sequence": "MAAAAVTRGTPGDSPSPRPLRPGVTLPPGTLTMNTKDTTEVAENSHHLKIFLPKKLLECLPRCALLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMEPVSWQCLYGCYVHSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHGIKWSCGNGAEEFSVEQLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLASISHSQPPEPPPLITPLPPELPKAHTSPSSSSSSSSSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQAEPRPVSLAVVVGSEPSALPTPPSPAFDPDRFLNSPQRGQTYGGGQGVNPDFPEAEGTHTPCPALEPAAALEPQAAARGLPSQLGASGRRGNQFFIQDDDSGEELKGQETVPPVPSPPPSSPSSPATLQPSGRVTRGEALFGGSGGTSELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALNTITDFSPEWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDSQFRMSILERLEQMEKRMAEIAAAGQAPGQSPEAPPIQDEGQGPGFEARVVVLVESMIPRSTWRGPERLIHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFCWNRQALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEHPLALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAADGSPPPVPLLASEITMEMIPGQLSPGATETPLLLMDYEATRSKESVPSLSGPPLAQKDGTPPEDAGSPPAVDVIPVDMISLAKQIIEATPERIKREDFSGLPEAGASLREQTGTVGLSETMSWLASYLENVDHFPSSAPTSELPFERGRLAIPPTPSWAEFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPAHRPSGPLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGLAT", "length": 1238, "header": "tr|A0A9J7GDG4-1|A0A9J7GDG4_CRIGR Isoform 1 of Calmodulin-binding transcription activator 2 OS=Cricetulus griseus OX=10029 GN=Camta2 PE=3 SV=1 CANONICAL=A0A9J7GDG4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7N5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4/entry#A0A9J7H7N5-1", "sequence": { "sequence": 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"length": 1206, "header": "tr|A0A9J7H7N5-1|A0A9J7H7N5_CRIGR Computationally mapped isoform of Calmodulin-binding transcription activator 2 OS=Cricetulus griseus OX=10029 GN=Camta2 PE=3 SV=1 CANONICAL=A0A9J7GDG4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1059, "start_aa": "Thr", "end_pos": 1059, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1059", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": 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"O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 7, "start_aa": "Thr", "end_pos": 7, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr7", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCD2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCD2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772126", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772126", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG4" } ], "pmid": "" } ] } ] }, 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Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278495", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278495" } ] }, { "annotation": "Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1#function" }, { "database": "UniProtKB", "id": "ARBA00057773", "url": "https://www.uniprot.org/uniprotkb/ARBA00057773#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tfpi", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1", "locus": {} } ], "crossref": [ { "id": "cd22613", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22613", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22614", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22614", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22615", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22615", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760115", "url": "https://www.ncbi.nlm.nih.gov/gene/100760115", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760115", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760115", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCE1", "url": "https://www.orthodb.org/?gene=A0A9J7GCE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10083:SF328", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10083:SF328", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027278495", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278495", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSIMRKEHVFWAFVCLLLSIVPELLSALPEEVDGHAKTTDSEQPPMKPKHTFCAMKVDDGPCKAMIRSYFFNIFTYQCEEFIYGGCRGNENRFETLEECKETCIRGYKKKTVKTPSGAEKPDFCFLEEDPGICRGLITRYFYNNQSKQCEQFKYGGCLGNRNNFETLDECKSICEDTGNELQTDNYTPDLNTANNTLIPQSTKTPSRWEYHGPSWCLSPADSGLCQANEKRFYYNSTIGKCRQFKYTGCGGNHNNFTTKKDCVRACKRGFLKRISKERTIKTQRRKEPSVKVVYEAFN", "length": 299, "header": "tr|A0A9J7GCE1-1|A0A9J7GCE1_CRIGR Isoform 1 of Tissue factor pathway inhibitor OS=Cricetulus griseus OX=10029 GN=Tfpi PE=4 SV=1 CANONICAL=A0A9J7GCE1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1/entry#A0A9J7GCE1-1", "sequence": { "sequence": "MTSIMRKEHVFWAFVCLLLSIVPELLSALPEEVDGHAKTTDSEQPPMKPKHTFCAMKVDDGPCKAMIRSYFFNIFTYQCEEFIYGGCRGNENRFETLEECKETCIRGYKKKTVKTPSGAEKPDFCFLEEDPGICRGLITRYFYNNQSKQCEQFKYGGCLGNRNNFETLDECKSICEDTGNELQTDNYTPDLNTANNTLIPQSTKTPSRWEYHGPSWCLSPADSGLCQANEKRFYYNSTIGKCRQFKYTGCGGNHNNFTTKKDCVRACKRGFLKRISKERTIKTQRRKEPSVKVVYEAFN", "length": 299, "header": "tr|A0A9J7GCE1-1|A0A9J7GCE1_CRIGR Isoform 1 of Tissue factor pathway inhibitor OS=Cricetulus griseus OX=10029 GN=Tfpi PE=4 SV=1 CANONICAL=A0A9J7GCE1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760115", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760115", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1" } ], "pmid": "" }, { "name": "cellular response to lipid", "id": "GO:0071396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071396", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GCE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCE1" }, { "id": "PS50279", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50279" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BPTI/Kunitz inhibitor", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 104, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 236, "end_pos": 238 }, { "start_pos": 256, "end_pos": 258 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GCH4-1", "uniprot_ac": "A0A9J7GCH4", "uniprot_id": "A0A9J7GCH4_CRIGR", "mass": { "chemical_mass": 167293.0, "monoisotopic_mass": 167293.0 }, "refseq": { "ac": "XP_027282775", "name": "LOW QUALITY PROTEIN: neuralized-like protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282775" }, "gene_names": [ { "name": "Neurl4", "type": "recommended", "evidence": [ { "id": "A0A9J7GCH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH4" } ] }, { "name": "Neurl4", "type": "synonym", "evidence": [ { "id": "XP_027282775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282775" } ] } ], "protein_names": [ { "name": "Neuralized-like protein 4", "type": "recommended", "evidence": [ { "id": "A0A9J7GCH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH4/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: neuralized-like protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027282775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282775" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282775" } ] }, { "annotation": "Promotes CCP110 ubiquitination and proteasome-dependent degradation. By counteracting accumulation of CP110, maintains normal centriolar homeostasis and preventing formation of ectopic microtubular organizing centers.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH4#function" }, { "database": "UniProtKB", "id": "ARBA00060334", "url": "https://www.uniprot.org/uniprotkb/ARBA00060334#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Neurl4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH4", "locus": {} } ], "crossref": [ { "id": "cd12887", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12887", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761129", "url": "https://www.ncbi.nlm.nih.gov/gene/100761129", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037962", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037962", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761129", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761129", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCH4", "url": "https://www.orthodb.org/?gene=A0A9J7GCH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12429", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12429", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12429:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12429:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07177", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07177", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282775", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"A0A9J7GCH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH7" } ] }, { "name": "LOC100774967", "type": "synonym", "evidence": [ { "id": "XP_027281918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281918" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7GCH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH7/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 4D1", "type": "synonym", "evidence": [ { "id": "XP_027281918", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281918" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281918" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100774967", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH7", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCH7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCH7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774967", "url": "https://www.ncbi.nlm.nih.gov/gene/100774967", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774967", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774967", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCH7", "url": "https://www.orthodb.org/?gene=A0A9J7GCH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281918", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281918", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPQNMTWVSEFILLGFSQTQELQKLLFVVFLFVYITTVVGNILIMVTVTFDPRLDMPMYFLLRNLAVIDLSYSTVTCPKMLVDFFHEIKTISYQGCMAQIFFFHLLGGGTVFFLSVMAYDRYIAISRPLHYVSIMNTRLCVGLVVAAWVGGFLHSIVQLSLMLPLPFCGPNVLDNFYCDVPQVLRLACTDTSLLEFLMISNSGMLVLIWFLLLLVSYTVILVMLRSHSGQARRKAASTCTTHIIVVSMIFIPCIYIYSRPFTPFPLDKAVSISYTVLTPMLNPMIYTLRNQEMQTAMKRLAKNLVLSKRDEL", "length": 313, "header": "tr|A0A9J7GCH7-1|A0A9J7GCH7_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100774967 PE=3 SV=1 CANONICAL=A0A9J7GCH7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCH7/entry#A0A9J7GCH7-1", "sequence": { "sequence": "MEPQNMTWVSEFILLGFSQTQELQKLLFVVFLFVYITTVVGNILIMVTVTFDPRLDMPMYFLLRNLAVIDLSYSTVTCPKMLVDFFHEIKTISYQGCMAQIFFFHLLGGGTVFFLSVMAYDRYIAISRPLHYVSIMNTRLCVGLVVAAWVGGFLHSIVQLSLMLPLPFCGPNVLDNFYCDVPQVLRLACTDTSLLEFLMISNSGMLVLIWFLLLLVSYTVILVMLRSHSGQARRKAASTCTTHIIVVSMIFIPCIYIYSRPFTPFPLDKAVSISYTVLTPMLNPMIYTLRNQEMQTAMKRLAKNLVLSKRDEL", "length": 313, "header": "tr|A0A9J7GCH7-1|A0A9J7GCH7_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100774967 PE=3 SV=1 CANONICAL=A0A9J7GCH7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 159 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613601.1) and transcript sequence (IACG01093912.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003495855.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495855" } ] }, { "annotation": "Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites. 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Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280639", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280639" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113836634", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCK5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCK5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113836634", "url": "https://www.ncbi.nlm.nih.gov/gene/113836634", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020479", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020479", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113836634", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836634", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCK5", "url": "https://www.orthodb.org/?gene=A0A9J7GCK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45921", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45921", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45921:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45921:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280639", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280639", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPTPRGPDGASYLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV", "length": 291, "header": "tr|A0A9J7GCK5-1|A0A9J7GCK5_CRIGR Isoform 1 of T-cell leukemia homeobox protein 3 OS=Cricetulus griseus OX=10029 GN=LOC113836634 PE=4 SV=1 CANONICAL=A0A9J7GCK5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5/entry#A0A9J7GCK5-1", "sequence": { "sequence": "MEAPASAQTPHPHEPISFGIDQILNSPDQDSAPTPRGPDGASYLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQPDPLCLHNSSLFALQNLQPWEEDSSKVPAVTSLV", "length": 291, "header": "tr|A0A9J7GCK5-1|A0A9J7GCK5_CRIGR Isoform 1 of T-cell leukemia homeobox protein 3 OS=Cricetulus griseus OX=10029 GN=LOC113836634 PE=4 SV=1 CANONICAL=A0A9J7GCK5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113836634", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836634", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCK5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GCK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK5" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 164, "end_pos": 224, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GCK9-1", "uniprot_ac": "A0A9J7GCK9", "uniprot_id": "A0A9J7GCK9_CRIGR", "mass": { "chemical_mass": 35634.0, "monoisotopic_mass": 35634.0 }, "refseq": { "ac": "XP_003509221", "name": "olfactory receptor 1468 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509221" }, "gene_names": [ { "name": "LOC100766727", "type": "recommended", "evidence": [ { "id": "A0A9J7GCK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK9" } ] }, { "name": "LOC100766727", "type": "synonym", "evidence": [ { "id": "XP_003509221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509221" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7GCK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK9/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1468 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003509221", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509221" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614665.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509221" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766727", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK9", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15918", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15918", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766727", "url": "https://www.ncbi.nlm.nih.gov/gene/100766727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766727", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766727", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCK9", "url": "https://www.orthodb.org/?gene=A0A9J7GCK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JP90", "url": "https://www.orthodb.org/?gene=A0A9J7JP90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509221", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509221", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCK9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JP90-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JP90-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGNTKRNQTVISQFLLLGLPIPTEHQNLFYSLFLAMYLITVLGNLLIIILIQLDSHLHTPMYSLLSNLSFSDLCFSSVTMPKLLQNMQSQVPSIPYAGCLAQMYFFLFFADLESFLLVAMAYDRYVAICFPLHYTSIMSPKLCVGLVVFSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTHVNELVIFITGGLILVIPFVLIVVSYARIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTVIGLYLCPSANNSTLKETVMGMMYTVVTPMLNPFIYSLRNRDMKGALFRVLCKKKILFCL", "length": 317, "header": "tr|A0A9J7GCK9-1|A0A9J7GCK9_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100766727 PE=3 SV=1 CANONICAL=A0A9J7GCK9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK9/entry#A0A9J7GCK9-1", "sequence": { "sequence": "MQGNTKRNQTVISQFLLLGLPIPTEHQNLFYSLFLAMYLITVLGNLLIIILIQLDSHLHTPMYSLLSNLSFSDLCFSSVTMPKLLQNMQSQVPSIPYAGCLAQMYFFLFFADLESFLLVAMAYDRYVAICFPLHYTSIMSPKLCVGLVVFSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTHVNELVIFITGGLILVIPFVLIVVSYARIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTVIGLYLCPSANNSTLKETVMGMMYTVVTPMLNPFIYSLRNRDMKGALFRVLCKKKILFCL", "length": 317, "header": "tr|A0A9J7GCK9-1|A0A9J7GCK9_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100766727 PE=3 SV=1 CANONICAL=A0A9J7GCK9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JP90-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCK9/entry#A0A9J7JP90-1", "sequence": { "sequence": "MVEENQTVISQFLLLGLPIPTEHQNLFYSLFLAMYLITVLGNLLIIILIQLDSHLHTPMYSLLSNLSFSDLCFSSVTMPKLLQNMQSQVPSIPYAGCLAQMYFFLFFADLESFLLVAMAYDRYVAICFPLHYTSIMSPKLCVGLVVFSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTHVNELVIFITGGLILVIPFVLIVVSYARIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTVIGLYLCPSANNSTLKETVMGMMYTVVTPMLNPFIYSLRNRDMKGALFRVLCKKKILFCL", "length": 314, "header": "tr|A0A9J7JP90-1|A0A9J7JP90_CRIGR Computationally mapped isoform of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100766727 PE=3 SV=1 CANONICAL=A0A9J7GCK9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MRPQPSPAVPSGGREGRLPRVRAQTVGIPAAQRTNPLHSHGMRLLWGPRKPFLTLLLLVSIKQVTGSLLEDTTRKWAQYREKCLRDLLNEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWNEESPGRAYRHCLAQGTWQTRVNATAIWQDDSECSENHSFKQNVDHYSLLSTLQLVYTVGYSLSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRALAVLVKDIIFYNSYSKRPDNESGWMSYLSEMSASCRCVQVLLHYFVGANHLWLLVEGLYLHALLEPTVLPERRLWPRYLVVGWAFPMLFVIPWGFARAHLENTGCWATNGNKKIWWIIRGPMLLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLLLIPLLGVHEVLFSFITDDQVQGFSKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKSWGRFLLARHWGCRVCVLGKNFRFLGKCSKKLSEGDGAETLRKLQSSTCSSHLASETLGELGARPHQGRGAWPRGSSLSESSEGDFTLANTMEEILEESEI", "length": 550, "header": "tr|A0A9J7GCM0-1|A0A9J7GCM0_CRIGR Isoform 1 of Glucagon-like peptide 2 receptor OS=Cricetulus griseus OX=10029 GN=Glp2r PE=3 SV=1 CANONICAL=A0A9J7GCM0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCM0/entry#A0A9J7GCM0-1", "sequence": { "sequence": "MRPQPSPAVPSGGREGRLPRVRAQTVGIPAAQRTNPLHSHGMRLLWGPRKPFLTLLLLVSIKQVTGSLLEDTTRKWAQYREKCLRDLLNEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPSYLPWWNEESPGRAYRHCLAQGTWQTRVNATAIWQDDSECSENHSFKQNVDHYSLLSTLQLVYTVGYSLSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRALAVLVKDIIFYNSYSKRPDNESGWMSYLSEMSASCRCVQVLLHYFVGANHLWLLVEGLYLHALLEPTVLPERRLWPRYLVVGWAFPMLFVIPWGFARAHLENTGCWATNGNKKIWWIIRGPMLLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLLLIPLLGVHEVLFSFITDDQVQGFSKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKSWGRFLLARHWGCRVCVLGKNFRFLGKCSKKLSEGDGAETLRKLQSSTCSSHLASETLGELGARPHQGRGAWPRGSSLSESSEGDFTLANTMEEILEESEI", "length": 550, "header": "tr|A0A9J7GCM0-1|A0A9J7GCM0_CRIGR Isoform 1 of Glucagon-like peptide 2 receptor OS=Cricetulus griseus OX=10029 GN=Glp2r PE=3 SV=1 CANONICAL=A0A9J7GCM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCM0" } ], "pmid": "" }, { "name": "adenylate cyclase-modulating G protein-coupled receptor signaling pathway", "id": "GO:0007188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007188", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "peptide hormone binding", "id": "GO:0017046", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017046", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCM0" } ], "pmid": "" }, { "name": "glucagon receptor activity", "id": "GO:0004967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004967", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCM0", "url": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282472" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCM6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Coro6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCM6", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCM6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCM6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756161", "url": "https://www.ncbi.nlm.nih.gov/gene/100756161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", 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"MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASDDTTVMVWQIPDYTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEALLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKNQVVANNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLKEGYVPPKHRELRVTKRNILDVRPPAGPRRSQSASEAPLSQQHTLETLLEEIKALRERVQAQEERITALENMLCELVDGTD", "length": 432, "header": "tr|A0A8C2QCU5-1|A0A8C2QCU5_CRIGR Computationally mapped isoform of Coronin OS=Cricetulus griseus OX=10029 GN=Coro6 PE=3 SV=1 CANONICAL=A0A9J7GCM6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCM6/entry#A0A9J7GCM6-1", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASDDTTVMVWQIPDYTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEALLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKNQVVAERARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLKEGYVPPKHRELRVTKRNILDVRPPAGPRRSQSASEAPLSQQHTLETLLEEIKALRERVQAQEERITALENMLCELVDGTD", "length": 472, "header": "tr|A0A9J7GCM6-1|A0A9J7GCM6_CRIGR Isoform 1 of Coronin OS=Cricetulus griseus OX=10029 GN=Coro6 PE=3 SV=1 CANONICAL=A0A9J7GCM6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A9J7GCM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCM6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCM6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GCM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCM6" }, { "id": "SM01166", "database": "SMART", "url": 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}, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"XP_027282912", "name": "growth arrest-specific protein 7 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282912" }, "gene_names": [ { "name": "Gas7", "type": "recommended", "evidence": [ { "id": "A0A9J7GCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCN3" } ] }, { "name": "Gas7", "type": "synonym", "evidence": [ { "id": "XP_027282912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282912" } ] } ], "protein_names": [ { "name": "Growth arrest-specific protein 7", "type": "recommended", "evidence": [ { "id": "A0A9J7GCN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCN3/entry#names_and_taxonomy" } ] }, { "name": "growth arrest-specific protein 7 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027282912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282912" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282912" } ] }, { "annotation": "May play a role in promoting maturation and morphological differentiation of cerebellar neurons.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCN3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCN3#function" }, { "database": "UniProtKB", "id": "ARBA00055699", "url": "https://www.uniprot.org/uniprotkb/ARBA00055699#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCN3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCN3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gas7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCN3", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCN3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07649", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07649", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11829", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11829", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768686", "url": "https://www.ncbi.nlm.nih.gov/gene/100768686", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": 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"Enzyme and Pathway" ] }, { "id": "A0A9J7GCN3", "url": "https://www.orthodb.org/?gene=A0A9J7GCN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23065:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23065:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16623", "url": 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"MAGARCRTLYPFSGERHSQGLRFAAGELLTLLQVPDGGWWEGEKDDGLRGWFPASYVQLLEKPGMVPPPPGEESQTVILPPGWHSYLSPQGRRYYVNTTTNETTWERPSSSPGISASPGPHRSSLPPTVNGYHASGTPAHPPETAHMSLRKSTGDSQNLGSSSPGKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEEYAKNLAKLSQNSLAAQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQKDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI", "length": 476, "header": "tr|A0A9J7GCN3-1|A0A9J7GCN3_CRIGR Isoform 1 of Growth arrest-specific protein 7 OS=Cricetulus griseus OX=10029 GN=Gas7 PE=4 SV=1 CANONICAL=A0A9J7GCN3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCN3/entry#A0A9J7GCN3-1", "sequence": { "sequence": 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"MEQLTTLPQLGDRGAMEPWALPAWQCWTQGRGCEPEDASPSIADTPTALQVRGLRSEESSKPEGAHRPAGNTDPEGTDTGLPKLGQQAESHGYSCPQPEDEDAQACKAKSNVGFGVRSNLELLRALGELQQRCTILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERAQKLQETNMRVVSAPVPRPGSSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRELQARLTLVGKEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQREPLRPARPPGPTALSRVGAPAPGAPGEAILQDDVDSPQVALGEPEKQQRVQQLESELCKKRKKCESLEQEARKKQRRCEELELQLRAAQNENARLVEENSRLSGRATEKEQVEWENAELKGQLLGVKQERDSALRRSQGLQSKLESLEQVLKRMREVAQRRQQLEVEHEQARLSLQEKQEEVRRLQQAQAEAKREHEGAVQLLESTLDSMQARVRELEGQCRSQTERFSLLAQELQAFRLHPGPLDLLTSALGCSVLGDHPPPHCCCSTPQPCHGSGPKDLDLPPGSPGRCTPKSSEPALATLAGVPRRTAKKVESLSNSSRSESVHNSPKSCPTPEVDTASEVEELEVDSVSLLPAAPEGNSGGARIQVFLARYSYNPLEGPNENPEAELPLTAGEYIYIYGDMDEDGFFEGELMDGRRGLVPSNFVERVSDDDLLTSLPRELADLSHSSGPELSFLSGGGGGCSSGGQSSGGRSQPRPEEEAAGDELSLSPPPEGLGEPLAVPYPRRLVVLKQLAHSVVLAWELPPEKVDVRGFHIFVNGELRQALGPGVPPKAVLENMDLQAGPLHVSVQALTSRGSSDPLRCCLAVGARAGVVPSQLRIHRLTATSAEITWVPGNSNLAHAIYLNGEECPPARPSTYWATFCHLRPGTLYQARVEAQIPSQGPWEPGWERPEQRAATLQFTTLPAGLPDAPLDVQVEPGPSPGILMISWLPVTIDAAGTSNGVRVTGYTIYADRQKIMEVASPTAGSVLVEVSQLQLLQACHEVTVRTMSPHGESTDSIPAPVAPALDPACQSARMSCLSPRPSPEVRAPLASVSPGLGDPSFPLRHPAPDGTQDSPASLPMEMSKGSQEEPPVPCSQEESGAAVLGTSEEKRAIEPALGWEGPSPVAPSLAKQEVEWTSGEVGPTPSSTQGEPAQKAPSTEACHGGDLGSGLKLRAEKEDVSELGVRLVNSLVDHGRNSDLSDIQEEEEEEEEEDEEEDLGSRPCSPQKQVASNSIRENGAKPQPDPLCETDSDEEILEQILELPVQQLCSKKLFSIPEEEEEEEEEEEEEEEEEEEGQEQSEPASSCQDPSQSELALQGLDCDSSQSQGPGLCPLSPEPSRAREHLEDVLGIAGGNSRRRGGGSPEKLPNRKRPQDPREHCSRLLGNGGPQTTARPGPLRERGSLPVIEGIRVGQEAGGRGRPGLSRRCPRGPAPESSLVSCLSPKCLEISIEYDSEDELEAGSGGIGITSSCYPTDGEPWGTAAVGRSRGPLKVNSGPNPYLRLPAWEKGEPERRGRSATGRTKEPPSRAVETGESRGPDNFGRRGPQRRGARVPRPATTELAPTRSPLEAPAHQNLPVRVFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDSDGFYRGESGGRTGYIPCNMVAEVAVDSPAGRQQLLQRGFLPPDVLTEVLGDGLSVYPSAHMTGPPPKPRRSKKAELEGPQPCPGPPKLIHSALLKTSRPMVAAFDYNPRENSPNMDVEAELPFRAGDVITVFGNMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLESGTSQAESQRTRRRRVQC", "length": 1854, "header": "tr|A0A9J7GCP7-1|A0A9J7GCP7_CRIGR Isoform 1 of Peripheral-type benzodiazepine receptor-associated protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tspoap1 PE=3 SV=1 CANONICAL=A0A9J7GCP7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1029, "start_aa": "Thr", "end_pos": 1029, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1029", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1191, "start_aa": "Thr", "end_pos": 1191, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1191", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 293, "start_aa": "Thr", "end_pos": 293, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr293", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 616, "start_aa": "Thr", "end_pos": 616, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr616", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCP7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCP7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752521", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752521", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "calyx of Held", "id": "GO:0044305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044305", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCP7" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "benzodiazepine receptor binding", "id": "GO:0030156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030156", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCP7" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels", "id": "GO:0099626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099626", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCP7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GCQ4-1", "uniprot_ac": "A0A9J7GCQ4", "uniprot_id": "A0A9J7GCQ4_CRIGR", "mass": { "chemical_mass": 36378.0, "monoisotopic_mass": 36378.0 }, "refseq": { "ac": "XP_027282054", "name": "olfactory receptor 11L1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282054" }, "gene_names": [ { "name": "LOC100770472", "type": "recommended", "evidence": [ { "id": "A0A9J7GCQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCQ4" } ] }, { "name": "LOC100770472", "type": "synonym", "evidence": [ { "id": "XP_027282054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282054" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7GCQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCQ4/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 11L1", "type": "synonym", "evidence": [ { "id": "XP_027282054", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282054" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282052" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCQ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCQ5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100763568", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCQ5", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15421", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15421", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763568", "url": "https://www.ncbi.nlm.nih.gov/gene/100763568", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763568", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763568", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCQ5", "url": "https://www.orthodb.org/?gene=A0A9J7GCQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282052", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCQ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNFTNWMSNYFGQSDFTMVGFFIQSKHPVLLAVVIFVVFLMALSGNALLILLIHSDTRLHTPMYFFISQLSLMDMMYISVTVPKMFMDQVLGSHKISAAACGMQMFLYLTLAGTEFFLLAAMSYDRYVAICHPLRYPVLMNYRVCLLLMSVCWFLGSLDGFILTPVTMTFPFCGSREIHHFFCEVPAVTKLSCSDTWLYETLMYLCCVLMLLIPVTVISSSYSSILLTVHRMNSAEGRKKALATCSSHMTVVILFYGAAVYTYMLPASFHTPEKDMVVSVFYTILTPLLNPLIYSLRNKNITGALKKLLGVRPFS", "length": 315, "header": "tr|A0A9J7GCQ5-1|A0A9J7GCQ5_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100763568 PE=3 SV=1 CANONICAL=A0A9J7GCQ5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCQ5/entry#A0A9J7GCQ5-1", "sequence": { "sequence": "MNFTNWMSNYFGQSDFTMVGFFIQSKHPVLLAVVIFVVFLMALSGNALLILLIHSDTRLHTPMYFFISQLSLMDMMYISVTVPKMFMDQVLGSHKISAAACGMQMFLYLTLAGTEFFLLAAMSYDRYVAICHPLRYPVLMNYRVCLLLMSVCWFLGSLDGFILTPVTMTFPFCGSREIHHFFCEVPAVTKLSCSDTWLYETLMYLCCVLMLLIPVTVISSSYSSILLTVHRMNSAEGRKKALATCSSHMTVVILFYGAAVYTYMLPASFHTPEKDMVVSVFYTILTPLLNPLIYSLRNKNITGALKKLLGVRPFS", "length": 315, "header": "tr|A0A9J7GCQ5-1|A0A9J7GCQ5_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100763568 PE=3 SV=1 CANONICAL=A0A9J7GCQ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Isoform 1 of Hypermethylated in cancer 1 protein OS=Cricetulus griseus OX=10029 GN=Hic1 PE=3 SV=1 CANONICAL=A0A9J7GCR7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 303, "start_aa": "Thr", "end_pos": 303, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr303", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003614004.1) annotated using gene prediction method: Gnomon. 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13091", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13091:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13091:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10220", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10220", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003503853", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503853", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPVSLRELLMGASAWLGSESPGAPPAEGGGNATGAPEPPWREDEICVVGIFGKTALRLNSEKFSLVNTVCDRQVFPLFHHQDPGDPGPGIKTEAVSVGEAGGAGDPGAAAGDSLRGGMATAEGNRAEPGPQDFSLLQAYYNQESKVLYLILTSICDNSQLLRACRALQSGEAGGGLSLPHAETHEFWKHQEKLQCLSLLYLFSVCHILLLVHPTCSFDITYDRVFRALDGLRQKVLPLLKTAIKDCPVGKDWKLNCRPCPPRLLFLFQLNGALKVEPPRSQDTAHPDKPKKHSPKRRLQHALEDQIYRIFRKSRVLTNQSINCLFTVPANQAFVYIVPGSQEEDPIGMLLDQLRSHCTVKDPESLLVPAPLSGPRRYQVMRQHSRQQLSFHVDSSTSSSSGQLVDFTLREFLWQHVELVLSKKGFDDSVGRNPQPSHFELPTYQKWISAAAKLYEVAIDGKEEDLSSPTGELTSKILSSIKVLEGFLDIDTKFSENRCQKALPMAHSAYQSNLPHNYTMTVHKNQLAQALRVYSQHARGPAFHKYAMQLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTGACNCGRKQAPRDDPFDIKAANYDFYQLLEEKCCGKLDHINFPVFEPSTPDPAPAKNEPSPAPPDSDAEKLKEKEPQTQGESTSLSLALSLGQSTDSLGTYPADPQAGGDNPEVHGQGEVKSEKRPNLVDRQASTVEYLPGMLHSNCPKGLLPKFSSWSLVKLGPAKSYNFHTGLDQQGFVPGTNYLMPWDIVIRTRAEDEGDLDTNSWPAPNKAIPGKRSAVVMGRGRRRDDIARAFVGFEYEDSRGRRFMCSGPDKVMKVMGSGPKESALKALNSDMPLYILSSSQGRGLKPHYAQLMRLFVVVPDAPLQIILMPQVQPGPPPCPVFYPEKQEITLPPDGLWVLRFPYAYVTERGPCFPPKENVQLMSYKVLRGVLKAVTQ", "length": 991, "header": "tr|A0A9J7GCU5-1|A0A9J7GCU5_CRIGR Isoform 1 of Nonsense-mediated mRNA decay factor SMG8 OS=Cricetulus griseus OX=10029 GN=Smg8 PE=3 SV=1 CANONICAL=A0A9J7GCU5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU5/entry#A0A9J7GCU5-1", "sequence": { "sequence": "MAGPVSLRELLMGASAWLGSESPGAPPAEGGGNATGAPEPPWREDEICVVGIFGKTALRLNSEKFSLVNTVCDRQVFPLFHHQDPGDPGPGIKTEAVSVGEAGGAGDPGAAAGDSLRGGMATAEGNRAEPGPQDFSLLQAYYNQESKVLYLILTSICDNSQLLRACRALQSGEAGGGLSLPHAETHEFWKHQEKLQCLSLLYLFSVCHILLLVHPTCSFDITYDRVFRALDGLRQKVLPLLKTAIKDCPVGKDWKLNCRPCPPRLLFLFQLNGALKVEPPRSQDTAHPDKPKKHSPKRRLQHALEDQIYRIFRKSRVLTNQSINCLFTVPANQAFVYIVPGSQEEDPIGMLLDQLRSHCTVKDPESLLVPAPLSGPRRYQVMRQHSRQQLSFHVDSSTSSSSGQLVDFTLREFLWQHVELVLSKKGFDDSVGRNPQPSHFELPTYQKWISAAAKLYEVAIDGKEEDLSSPTGELTSKILSSIKVLEGFLDIDTKFSENRCQKALPMAHSAYQSNLPHNYTMTVHKNQLAQALRVYSQHARGPAFHKYAMQLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTGACNCGRKQAPRDDPFDIKAANYDFYQLLEEKCCGKLDHINFPVFEPSTPDPAPAKNEPSPAPPDSDAEKLKEKEPQTQGESTSLSLALSLGQSTDSLGTYPADPQAGGDNPEVHGQGEVKSEKRPNLVDRQASTVEYLPGMLHSNCPKGLLPKFSSWSLVKLGPAKSYNFHTGLDQQGFVPGTNYLMPWDIVIRTRAEDEGDLDTNSWPAPNKAIPGKRSAVVMGRGRRRDDIARAFVGFEYEDSRGRRFMCSGPDKVMKVMGSGPKESALKALNSDMPLYILSSSQGRGLKPHYAQLMRLFVVVPDAPLQIILMPQVQPGPPPCPVFYPEKQEITLPPDGLWVLRFPYAYVTERGPCFPPKENVQLMSYKVLRGVLKAVTQ", "length": 991, "header": "tr|A0A9J7GCU5-1|A0A9J7GCU5_CRIGR Isoform 1 of Nonsense-mediated mRNA decay factor SMG8 OS=Cricetulus griseus OX=10029 GN=Smg8 PE=3 SV=1 CANONICAL=A0A9J7GCU5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755762", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755762", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQ80-1", "protein_name": "Nonsense-mediated mRNA decay factor SMG8", "gene_name": "Smg8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGPVSLRELLMGASAWLGSESPGGPSAEGGGNAAAAPEPPWREDEICVVGIFGKTALRLNSEKFSLVNTVCDRQVFPLFHHQDPGDPGPGIKTKPVSVGEAGGAGDPGAAAGDSLRGGMATAEGNRAEPGPQDFSLLQAYYNQESKVLYLILTSICDNSQLLRACRALQSGEAGGGLSLPHAETHEFWKHQEKLQCLSLLYLFSVCHILLLVHPTCSFDITYDRVFRALDGLRQKVLPLLKTAIKDCPVGKDWKLNCRPCPPRLLFLFQLNGALKVEPPRSQDTAHPDKPKKHSPKRRLQHALEDQIYRIFRKSRVLTNQSINCLFTVPANQAFVYIVPGSQEEDPIGMLLDQLRSHCTVKDPESLLVPAPLSGPRRYQAMRQHSRQQLSFHIDSSTSSSSGQLVDFTLREFLWQHVELVLSKKGFDDSVGRNPQPSHFELPTYQKWISAAAKLYEVAIDGKEEDLGSPTGELTSKILSSIKVLEGFLDIDTKFSENRCQKALPMAHSAYQSNLPHNYTMTVHKNQLAQALRVYSQHARGPAFHKYAMQLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTGACNCGRKQAPRDDPFDIKAANYDFYQLLEEKCCGKLDHINFPVFEPSTPDPAPAKNEPCPTPADSDAEKLKEKEPQTQGEGTSLSLALSLGQSTDSLGTYPADPQAGGDNPDVHGQGEVKSEKRPNLVDRQASTVEYLPGMLHSNCPKGLLPKFSSWSLVKLGPAKSYNFHTGLDQQGFVPGTNYLMPWDIVIRTRAEDEGDLDTNSWPAPNKAIPGKRSAVVMGRGRRRDDIARAFVGFEYEDSRGRRFMCSGPDKVMKVMGSGPKESALKALNSDMPLYILSSSQGRGLKPHYAQLMRLFVVVPDAPLQIILMPQVQPGPPPCPVFYPEKQELTLPPDGLWVLRFPYAYVTERGPCFPPKENVQLMSYKVLRGVLRAVTQ", "length": 991 }, "evidence": [ { "id": "A0A9J7GCU5", "url": "https://omabrowser.org/oma/group/A0A9J7GCU5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FBA3-1", "protein_name": "Nonsense-mediated mRNA decay factor SMG8", "gene_name": "smg8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVPMNIKALLQSEIIEDAADKDEGVCVLGIFGKSAMQPGSAKDSLINTLANKHIFSLFGSDDTDSPGGGAAIQAYYNQENRVLYLVLTSVFDNRHLIRACESLTVGLGHAEAHEFWKAAEKEHCLQLLYLFSLCHILLLVHPTCSFDVSYDRMFRALDALRQKALPLLRAAIKDSPISKEWKLNCRPCPPRLLFVFQMNGALRVGSCMGGNGTDGTGVEKPKKHSPRRRMQHALEDQIYRIFRKSRVLTNQSSNCLFTVPANQAFVYVVGGPDEDPIGTLLGHLRSNCAFRENEGGTPVPGQRRYQQMRHSNRQPSFNVESSLSSGGQLVDCTLKEFLWQHVELVLTKKGFDDSVGRNPQPSHFELPTYTKWVHAAYKLYQVMIESVEEDAAEISLKVQGQLKVLEGFLDADAKFSENRCQKALPLAHSAYQSNLPHNYTTTVHKNQLAQALRVYSQHARGVAFQRYALQLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHLLPKPGEKPEMEHNPPILYHNSRGRSTSSCNCGRKQSPREDPFDIQTANYDFYQMLEEKCCAKLERINFPVFQASTPDPAPASDEVPRPGEVPPSGEADRLKEKETSTHTPGESTSLSLALSLGQSTDSLGTYADGAEGQEKRPSLVDRQPSTVEYLPGMLHSGCPKGLLPKFSSWSLVKLGPAKSYNSLTGLEQPGFLPGSAFLLPWDVVIRSRSEEDVGSLEPLDGGPASWPAPNKASAGKRGSAGGIGRGRRRDDVARAFVGFEYEDSRGRRFLSSGPDKVVKVLGQGGPKEPATRCLNSDMPLYIPSPAQGRGIKPHYAQLARLFVVVPDAPLEIVLNPQVQPGLPPCPIFHPEQPEVVLPSDGLWVLRFPYAYVTDRGPCYPPKENQPLANFRVLRGILRANTTSSTPQ", "length": 916 }, "evidence": [ { "id": "A0A9J7GCU5", "url": "https://omabrowser.org/oma/group/A0A9J7GCU5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3LLC0-1", "protein_name": "Nonsense-mediated mRNA decay factor SMG8", "gene_name": "SMG8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGPVSLRELLMGASAWTGAESPEGSPTEGGSSAAGGPEPPWREDEICVVGIFGKTALRLNSEKFSLVNTVCDRQVFPLFRQEDPGDSGPGIRTEAGAVGEAGGAGDPGAGAGSGDPVRGGVAAAEGNRTEPGSQDYSLLQAYYNQESKVLYLLLTSICDNSQLLRACRALQSGEAGGGLSLPHAEAHEFWKHQEKLQCLSLLYLFSVCHILLLVHPTCSFDITYDRVFRALDGLRQKVLPLLKTAIKDCPVGKDWKLNCRPCPPRLLFLFQLNGALKVEPPRNQDPAHPDKPKKHSPKRRLQHALEDQIYRIFRKSRVLTNQSINCLFTVPANQAFVYIVPGSQEEDPVGMLLDQLRSHCTVKDPESLLVPAPLSGSRRYQVMRQQSRQQLSFHIDTSSSSSSGQLVDFTLREFLWQHVELVLSKKGFDDSVGRNPQPSHFELPTYQKWISAASKLYEVAIDGKEEDLGSPTGELTSKILSSIKVLEGFLDIDTKFSENRCQKALPMAHSAYQSNLPHNYTMTVHKNQLAQALRVYSQHARGPAFHKYAMQLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTGACNCGRKQAPRDDPFDIKAANYDFYQLLEEKCCGKLDHINFPVFEPSTPDPAPAKNESSPAPPDADADKLKEKEPQTQGESTSLSLALSLGQSTDSLGTYPADPQAGGDNPEVHGPGEVKTEKRPNLVDRQASTVEYLPGMLHSNCPKGLLPKFSSWSLVKLGPAKSYNFHTGLDQQGFIPGTNYLMPWDIVIRTRAEDEGDLDTNSWPAPNKAIPGKRSAVVMGRGRRRDDIARAFVGFEYEDSRGRRFMCSGPDKVMKVMGSGPKESALKALNSDMPLYILSSSQGRGLKPHYAQLMRLFVVVPDAPLQIILMPQVQPGPPPCPVFYPEKQEITLPSDGLWVLRFPYAYVTERGPCFPPKENVQLMSYKVLRGVLKAITQ", "length": 993 }, "evidence": [ { "id": "A0A9J7GCU5", "url": "https://omabrowser.org/oma/group/A0A9J7GCU5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8ND04-1", "protein_name": "Nonsense-mediated mRNA decay factor SMG8", "gene_name": "SMG8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGPVSLRDLLMGASAWMGSESPGGSPTEGGGSAAGGPEPPWREDEICVVGIFGKTALRLNSEKFSLVNTVCDRQVFPLFRHQDPGDPGPGIRTEAGAVGEAGGAEDPGAAAGGSVRGSGAVAEGNRTEAGSQDYSLLQAYYSQESKVLYLLLTSICDNSQLLRACRALQSGEAGGGLSLPHAEAHEFWKHQEKLQCLSLLYLFSVCHILLLVHPTCSFDITYDRVFRALDGLRQKVLPLLKTAIKDCPVGKDWKLNCRPCPPRLLFLFQLNGALKVEPPRNQDPAHPDKPKKHSPKRRLQHALEDQIYRIFRKSRVLTNQSINCLFTVPANQAFVYIVPGSQEEDPVGMLLDQLRSHCTVKDPESLLVPAPLSGPRRYQVMRQHSRQQLSFHIDSSSSSSSGQLVDFTLREFLWQHVELVLSKKGFDDSVGRNPQPSHFELPTYQKWISAASKLYEVAIDGKEEDLGSPTGELTSKILSSIKVLEGFLDIDTKFSENRCQKALPMAHSAYQSNLPHNYTMTVHKNQLAQALRVYSQHARGPAFHKYAMQLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTGACNCGRKQAPRDDPFDIKAANYDFYQLLEEKCCGKLDHINFPVFEPSTPDPAPAKNESSPAPPDSDADKLKEKEPQTQGESTSLSLALSLGQSTDSLGTYPADPQAGGDNPEVHGQVEVKTEKRPNFVDRQASTVEYLPGMLHSNCPKGLLPKFSSWSLVKLGPAKSYNFHTGLDQQGFIPGTNYLMPWDIVIRTRAEDEGDLDTNSWPAPNKAIPGKRSAVVMGRGRRRDDIARAFVGFEYEDSRGRRFMCSGPDKVMKVMGSGPKESALKALNSDMPLYILSSSQGRGLKPHYAQLMRLFVVVPDAPLQIILMPQVQPGPPPCPVFYPEKQEITLPPDGLWVLRFPYAYVTERGPCFPPKENVQLMSYKVLRGVLKAVTQ", "length": 991 }, "evidence": [ { "id": "A0A9J7GCU5", "url": "https://omabrowser.org/oma/group/A0A9J7GCU5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VE18-1", "protein_name": "Nonsense-mediated mRNA decay factor SMG8", "gene_name": "Smg8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGPVSLRELLMGASAWLGSESPGGPSAEGGGNAAGTPEPPWREDEICVVGIFGKTALRLNSEKFSLVNTVCDRQVFPLFHHQDPGDPGTGIKTKAVSVGEAGGAGDPGAAAGDSLRGGMATAEGNRAEPGPQDFSLLQAYYNQESKVLYLILTSICDNSQLLRACRALQSGEAGGGLSLPHAETHEFWKHQEKLQCLSLLYLFSVCHILLLVHPTCSFDITYDRVFRALDGLRQKVLPLLKTAIKDCPVGKDWKLNCRPCPPRLLFLFQLNGALKVEPPRSQDTAHPDKPKKHSPKRRLQHALEDQIYRIFRKSRVLTNQSINCLFTVPANQAFVYIVPGSQEEDPIGMLLDQLRSHCTVKDPESLLVPAPLSGPRRYQAMRQHSRQQLSFHIDSSTSSSSGQLVDFTLREFLWQHVELVLSKKGFDDSVGRNPQPSHFELPTYQKWISAAAKLYEVAIDGKEEDLGSPTGELTSKILSSIKVLEGFLDIDTKFSENRCQKALPMAHSAYQSNLPHNYTMTVHKNQLAQALRVYSQHARGPAFHKYAMQLHEDCYKFWSNGHQLCEERSLTDQHCVHKFHSLPKSGEKPEADRNPPVLYHNSRARSTGACNCGRKQAPRDDPFDIKAANYDFYQLLEEKCCGKLDHINFPVFEPSTPDPAPAKNEPSPAPPDSDAEKLKEKEPQTQGESTSLSLALSLGQSTDSLGTYPADPQAGGDNPEVHGQGEGKSEKRPNLVDRQASTVEYLPGMLHSNCPKGLLPKFSSWSLVKLGPAKSYNFHTGLDQQGFVPGTNYLMPWDIVIRTRAEDEGDLDTNSWPAPNKAIPGKRSAVVMGRGRRRDDIARAFVGFEYEDSRGRRFMCSGPDKVMKVMGSGPKESALKALNSDMPLYILSSSQGRGLKPHYAQLMRLFVVVPDAPLQIILMPQVQPGPPPCPVFYPEKQEITLPPDGLWVLRFPYAYVTERGPCFPPKENVQLMSYKVLRGVLKAVTQ", "length": 991 }, "evidence": [ { "id": "A0A9J7GCU5", "url": "https://omabrowser.org/oma/group/A0A9J7GCU5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "id": "GO:0000184", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000184", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 320, "end_pos": 322 }, { "start_pos": 33, "end_pos": 35 }, { "start_pos": 518, "end_pos": 520 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GCW3-1", "uniprot_ac": "A0A9J7GCW3", "uniprot_id": "A0A9J7GCW3_CRIGR", "mass": { "chemical_mass": 75129.0, "monoisotopic_mass": 75129.0 }, "refseq": { "ac": "XP_027282190", "name": "T-box transcription factor TBX2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282190" }, "gene_names": [ { "name": "Tbx2", "type": "recommended", "evidence": [ { "id": "A0A9J7GCW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ] }, { "name": "Tbx2", "type": "synonym", "evidence": [ { "id": "XP_027282190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282190" } ] } ], "protein_names": [ { "name": "T-box transcription factor TBX2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027282190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282190" }, { "id": "A0A9J7GCW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282190" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tbx2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20188", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20188", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"Protein Classification" ] }, { "id": "IPR046360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764644", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764644", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCW3", "url": "https://www.orthodb.org/?gene=A0A9J7GCW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11267:SF82", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11267:SF82", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00907", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00907", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282190", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLPTLRLYEEHCKPERDGAESDASSCDPPPAREPPPSPSAAPSPLRLHRARAEEKPCAADSDPEPERPGDERAAAPLGRSPPRDTSPARLTEPERSRERRSPERGSKEPTEGGGDGPFGLRSLEKERAEARRKDEGRKDAGEGKEPSLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHPGQFAMGPGAFSAMGMGHLLASVAGGGGNSGGAGPGTAAGLDAGGLGPAASAASTAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRSPFLGSARPRLRFSPYQIPVTIPPSTSLLTTGLAAEGSKAAGGSSREPSPLPELALRKVGGPSRGALSPSGSAKEAASELQSIQRLVSGLESQRALSPGRESPK", "length": 713, "header": "tr|A0A9J7GCW3-1|A0A9J7GCW3_CRIGR Isoform 1 of T-box transcription factor TBX2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tbx2 PE=4 SV=1 CANONICAL=A0A9J7GCW3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GCW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3/entry#A0A9J7GCW3-1", "sequence": { "sequence": "MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPPGALAKPLPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEAKELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLPTLRLYEEHCKPERDGAESDASSCDPPPAREPPPSPSAAPSPLRLHRARAEEKPCAADSDPEPERPGDERAAAPLGRSPPRDTSPARLTEPERSRERRSPERGSKEPTEGGGDGPFGLRSLEKERAEARRKDEGRKDAGEGKEPSLAPLVVQTDSASPLGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHPGQFAMGPGAFSAMGMGHLLASVAGGGGNSGGAGPGTAAGLDAGGLGPAASAASTAAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSLSRSPFLGSARPRLRFSPYQIPVTIPPSTSLLTTGLAAEGSKAAGGSSREPSPLPELALRKVGGPSRGALSPSGSAKEAASELQSIQRLVSGLESQRALSPGRESPK", "length": 713, "header": "tr|A0A9J7GCW3-1|A0A9J7GCW3_CRIGR Isoform 1 of T-box transcription factor TBX2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tbx2 PE=4 SV=1 CANONICAL=A0A9J7GCW3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764644", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764644", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell fate specification", "id": "GO:0001708", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001708", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCW3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": 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"uniprot_canonical_ac": "A0A9J7GCY7-1", "uniprot_ac": "A0A9J7GCY7", "uniprot_id": "A0A9J7GCY7_CRIGR", "mass": { "chemical_mass": 50538.0, "monoisotopic_mass": 50538.0 }, "refseq": { "ac": "XP_016831570", "name": "COP9 signalosome complex subunit 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831570" }, "gene_names": [ { "name": "Cops3", "type": "recommended", "evidence": [ { "id": "A0A9J7GCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCY7" } ] }, { "name": "Cops3", "type": "synonym", "evidence": [ { "id": "XP_016831570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831570" } ] } ], "protein_names": [ { "name": "COP9 signalosome complex subunit 3", "type": "recommended", "evidence": [ { "id": "A0A9J7GCY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCY7/entry#names_and_taxonomy" } ] }, { "name": "COP9 signalosome complex subunit 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016831570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831570" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 140 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613960.1) and transcript sequence (JI891568.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016831570", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016831570" } ] }, { "annotation": "Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Essential to maintain the survival of epiblast cells and thus the development of the postimplantation embryo.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCY7#function" }, { "database": "UniProtKB", "id": "ARBA00056848", "url": "https://www.uniprot.org/uniprotkb/ARBA00056848#function" }, { "database": "UniProtKB", "id": "A0A9J7K0K6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0K6#function" }, { "database": "UniProtKB", "id": "A0A8C2MZL9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZL9#function" }, { "database": "UniProtKB", "id": "A0A9J7GHK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCY7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cops3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCY7", "locus": {} } ], "crossref": [ { "id": "A0A9J7GCY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GCY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100760692", "url": "https://www.ncbi.nlm.nih.gov/gene/100760692", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048621", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048621", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050756", 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"MASALEQFVNSVRQLSAQGQMTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLAVLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSVHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKACHAPWSLYKLRYSGSEEPELRQNSTEKEELEGVSPWF", "length": 444, "header": "tr|A0A9J7GCY7-1|A0A9J7GCY7_CRIGR Isoform 1 of COP9 signalosome complex subunit 3 OS=Cricetulus griseus OX=10029 GN=Cops3 PE=3 SV=1 CANONICAL=A0A9J7GCY7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GHK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCY7/entry#A0A9J7GHK4-1", "sequence": { "sequence": "MASALEQFVNSVRQLSAQGQMTQLCELINKSGELLAKNLSHLDTVLGALDVQEHSLGVLAVLFVKFSMPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSVHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKETLELVGSLSV", "length": 417, "header": "tr|A0A9J7GHK4-1|A0A9J7GHK4_CRIGR Computationally mapped isoform of COP9 signalosome complex subunit 3 OS=Cricetulus griseus OX=10029 GN=Cops3 PE=3 SV=1 CANONICAL=A0A9J7GCY7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K0K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCY7/entry#A0A9J7K0K6-1", "sequence": { "sequence": "MPSVPDFETLFSQVQLFISTCNGEHIRYATDTFAGLCHQLTNALVERKQPLRGIGILKQAIDKMQMNTNQLTSVHADLCQLCLLAKCFKPALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAITTPAMAVSHIMLESYKKYILVSLILLGKVQQLPKYTSQIVGRFIKPLSNAYHELAQVYSTNNPSELRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEAEKYVLHMIEDGEIFASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCIELDERLKAMDQEITVNPQFVQKACHAPWSLYKLRYSGSEEPELRQNSTEKEELEGVSPWF", "length": 377, "header": "tr|A0A9J7K0K6-1|A0A9J7K0K6_CRIGR Computationally mapped isoform of COP9 signalosome complex subunit 3 OS=Cricetulus griseus OX=10029 GN=Cops3 PE=3 SV=1 CANONICAL=A0A9J7GCY7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCY7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760692", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760692", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCY7" } ], "pmid": "" }, { "name": "COP9 signalosome", "id": "GO:0008180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008180", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCY7", "url": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GCZ5-1", "uniprot_ac": "A0A9J7GCZ5", "uniprot_id": "A0A9J7GCZ5_CRIGR", "mass": { "chemical_mass": 54316.0, "monoisotopic_mass": 54316.0 }, "refseq": { "ac": "XP_027283141", "name": "synaptosomal-associated protein 47 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283141" }, "gene_names": [ { "name": "Snap47", "type": "recommended", "evidence": [ { "id": "A0A9J7GCZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ] }, { "name": "Snap47", "type": "synonym", "evidence": [ { "id": "XP_027283141", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283141" } ] } ], "protein_names": [ { "name": "Synaptosomal-associated protein 47", "type": "recommended", "evidence": [ { "id": "A0A9J7GCZ5", "database": "UniProtKB", "url": 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computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283141", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283141" } ] }, { "annotation": "May play a role in intracellular membrane fusion.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5#function" }, { "database": "UniProtKB", "id": "ARBA00055054", "url": "https://www.uniprot.org/uniprotkb/ARBA00055054#function" }, { "database": "UniProtKB", "id": "A0A8C2LK43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK43#function" }, { "database": "UniProtKB", "id": "A0A9J7GHL4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHL4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Snap47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5", "locus": {} } ], "crossref": [ { "id": "cd15854", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15854", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15888", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15888", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759226", "url": "https://www.ncbi.nlm.nih.gov/gene/100759226", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759226", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759226", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GCZ5", "url": "https://www.orthodb.org/?gene=A0A9J7GCZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19305", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19305", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19305:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19305:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283141", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283141", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LK43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LK43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GCZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GHL4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GHL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSDVHVHSWPCSYYLNLEKQWVPGKLTLTPHSLKFSADRTEEVLVGLPLSSITEIRKESSLFIFSAITVLEKGQAKHWFSSLRPSRNVVFNIIEHFWRELLLSQPGTAASTTSPMTRGQELVGLMASSQRRMEDTSKVLHHQGEQLDSVMRGLEKMESDLDVADRLLTELESPSWWPFSSKLWKTPAEAKTKEAVSIAACEPFGKEGVVIRVPAIVSQRTESHSKPGKLTVLVSGLEIHDSSSSLLHRFEREDVDDIKVHSPYEVSIRQRFIGKPDVAYRVISAKMPEVIPILEVQFSKKIELLEDALVFRSRARTSPAEGSCSIRHAASRLMGCNTHRELPTGGQEGEQLQLQKTWPLLSEGEAQELTQTMAHVPSGQGCWLRIALSAHHSIFTPSGKTRCFYGTHVCTSQEPIEKHGLTVGSWEVLSDDISDRQILSKLKGLALDTEAELERQDEALDGITVAVDQATLTVDKHNRRMRKLM", "length": 485, "header": "tr|A0A9J7GCZ5-1|A0A9J7GCZ5_CRIGR Isoform 1 of Synaptosomal-associated protein 47 OS=Cricetulus griseus OX=10029 GN=Snap47 PE=3 SV=1 CANONICAL=A0A9J7GCZ5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LK43-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5/entry#A0A8C2LK43-1", "sequence": { "sequence": "MSSDVHVHSWPCSYYLNLEKQWVPGKLTLTPHSLKFSADRTEEVLVGLPLSSITEIRKESSLFIFSAITVLEKGQAKHWFSSLRPSRNVVFNIIEHFWRELLLSQPGTAASTTSPMTRGQELVGLMASSQRRMEDTSKVLHHQGEQLDSVMRGLEKMESDLDVADRLLTELESPSWWPFSSKLWKTPAEAKTKEAVSIAACEPFGKEGVVIRVPAIVSQRTESHSKPGKLTVLVSGLEIHDSSSSLLHRFEREDVDDIKVHSPYEVSIRQRFIGKPDVAYRVISAKMPEVIPILEVQFSKKIELLEDALVFRSRARTSPAEGSCSIRHAASRLMGCNTHRELPTGGQEGEQLQLQKTWPLLSEGEAQELTQILSKLKGLALDTEAELERQDEALDGITVAVDQATLTVDKHNRRMRKLM", "length": 419, "header": "tr|A0A8C2LK43-1|A0A8C2LK43_CRIGR Computationally mapped isoform of Synaptosomal-associated protein 47 OS=Cricetulus griseus OX=10029 GN=Snap47 PE=3 SV=1 CANONICAL=A0A9J7GCZ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GCZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5/entry#A0A9J7GCZ5-1", "sequence": { "sequence": "MSSDVHVHSWPCSYYLNLEKQWVPGKLTLTPHSLKFSADRTEEVLVGLPLSSITEIRKESSLFIFSAITVLEKGQAKHWFSSLRPSRNVVFNIIEHFWRELLLSQPGTAASTTSPMTRGQELVGLMASSQRRMEDTSKVLHHQGEQLDSVMRGLEKMESDLDVADRLLTELESPSWWPFSSKLWKTPAEAKTKEAVSIAACEPFGKEGVVIRVPAIVSQRTESHSKPGKLTVLVSGLEIHDSSSSLLHRFEREDVDDIKVHSPYEVSIRQRFIGKPDVAYRVISAKMPEVIPILEVQFSKKIELLEDALVFRSRARTSPAEGSCSIRHAASRLMGCNTHRELPTGGQEGEQLQLQKTWPLLSEGEAQELTQTMAHVPSGQGCWLRIALSAHHSIFTPSGKTRCFYGTHVCTSQEPIEKHGLTVGSWEVLSDDISDRQILSKLKGLALDTEAELERQDEALDGITVAVDQATLTVDKHNRRMRKLM", "length": 485, "header": "tr|A0A9J7GCZ5-1|A0A9J7GCZ5_CRIGR Isoform 1 of Synaptosomal-associated protein 47 OS=Cricetulus griseus OX=10029 GN=Snap47 PE=3 SV=1 CANONICAL=A0A9J7GCZ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GHL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5/entry#A0A9J7GHL4-1", "sequence": { "sequence": "MSSDVHVHSWPCSYYLNLEKQWVPGKLTLTPHSLKFSADRTEEVLVGLPLSSITEIRKESSLFIFSAITVLEKGQAKHWFSSLRPSRNVVFNIIEHFWRELLLSQPGTAASTTSPMTRGQELVGLMASSQRRMEDTSKVLHHQGEQLDSVMRGLEKMESDLDVADRLLTELESPSWWPFSSKLWKTPAEAKTKEAVSIAACEPFGKEGVVIRVPAIVSQRTESHSKPGKLTVLVSGLEIHDSSSSLLHRFEREDVDDIKVHSPYEVSIRQRFIGKPDVAYRVISAKMPEVIPILEVQFSKKIELLEDALVFRSRARTSPAEGSCSIRHAASRLMGCNTHRELPTGGQEGEQLQLQKTWPLLSEGEAQELTQTMAHVPSGQGCWLRIALSAHHSIFTPSGKTRCFYGTHVCTSQEPIEKHGLTVGSWEVLSDDISDRS", "length": 437, "header": "tr|A0A9J7GHL4-1|A0A9J7GHL4_CRIGR Computationally mapped isoform of Synaptosomal-associated protein 47 OS=Cricetulus griseus OX=10029 GN=Snap47 PE=3 SV=1 CANONICAL=A0A9J7GCZ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759226", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759226", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" }, { "name": "SNAP receptor activity", "id": "GO:0005484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005484", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "synaptic vesicle fusion to presynaptic active zone membrane", "id": "GO:0031629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" }, { "name": "synaptic vesicle priming", "id": "GO:0016082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016082", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" }, { "name": "exocytic insertion of neurotransmitter receptor to postsynaptic membrane", "id": "GO:0098967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098967", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GCZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GCZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCZ5" }, { "id": "PS50192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "T-SNARE coiled-coil homology", "eco_id": "ECO_0000259", "start_pos": 135, "end_pos": 171, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GD03-1", "uniprot_ac": "A0A9J7GD03", "uniprot_id": "A0A9J7GD03_CRIGR", "mass": { "chemical_mass": 49638.0, "monoisotopic_mass": 49638.0 }, "refseq": { "ac": "XP_016832998", "name": "septin-12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832998" }, "gene_names": [ { "name": "Septin12", "type": "recommended", "evidence": [ { "id": "A0A9J7GD03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03" } ] }, { "name": "Septin12", "type": "synonym", "evidence": [ { "id": "XP_016832998", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832998" } ] } ], "protein_names": [ { "name": "Septin-9", "type": "recommended", "evidence": [ { "id": "A0A9J7GD03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03/entry#names_and_taxonomy" } ] }, { "name": "septin-12", "type": "synonym", "evidence": [ { "id": "XP_016832998", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832998" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614230.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016832998", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832998" } ] }, { "annotation": "Filament-forming cytoskeletal GTPase. May play a role in cytokinesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03#function" }, { "database": "UniProtKB", "id": "ARBA00046092", "url": "https://www.uniprot.org/uniprotkb/ARBA00046092#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Septin12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03", "locus": {} } ], "crossref": [ { "id": "A0A9J7GD03", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GD03", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01850", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01850", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771793", "url": "https://www.ncbi.nlm.nih.gov/gene/100771793", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771793", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771793", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GD03", "url": "https://www.orthodb.org/?gene=A0A9J7GD03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18884", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18884", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016832998", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832998", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GD03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD03-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHSDWNSWWLFSLPSTSSAVASSSCLSSSADCPILATCPSPPKGHLSPGLSQVIHNLDHTLRHHCILGPMDERRTPSPCSSRPSSPRTPPCEMLGSVGIEAVLDQLRIKAMKTGFEFNIMVVGQSGLGKSTMVNTLFKSKVWQSSLPNLEVPMPQTLELHSVTHVIEEKGLKLKLTVTDTPGFGDQINNDKWWVLWCAAPVPASWDPILSYINQQYEHYLQEELLITRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLRRLCRTVNVVPVIARADSLTIEERDAFRSRIQQNLKTHCIDVYPQKCFDEDVNDQLLNSKIREQIPFAVVGADREHVVNGRCVLGRKTKWGIIEVENMAHCEFLLLRDLLIRSHLQDLKDITHNVHYENYRVLRLNESHLLPRGPGWVNLAPASPGQLMSPGPGKARKRDNKDPREDEC", "length": 439, "header": "tr|A0A9J7GD03-1|A0A9J7GD03_CRIGR Isoform 1 of Septin-9 OS=Cricetulus griseus OX=10029 GN=Septin12 PE=3 SV=1 CANONICAL=A0A9J7GD03-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GD03-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03/entry#A0A9J7GD03-1", "sequence": { "sequence": "MSHSDWNSWWLFSLPSTSSAVASSSCLSSSADCPILATCPSPPKGHLSPGLSQVIHNLDHTLRHHCILGPMDERRTPSPCSSRPSSPRTPPCEMLGSVGIEAVLDQLRIKAMKTGFEFNIMVVGQSGLGKSTMVNTLFKSKVWQSSLPNLEVPMPQTLELHSVTHVIEEKGLKLKLTVTDTPGFGDQINNDKWWVLWCAAPVPASWDPILSYINQQYEHYLQEELLITRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLRRLCRTVNVVPVIARADSLTIEERDAFRSRIQQNLKTHCIDVYPQKCFDEDVNDQLLNSKIREQIPFAVVGADREHVVNGRCVLGRKTKWGIIEVENMAHCEFLLLRDLLIRSHLQDLKDITHNVHYENYRVLRLNESHLLPRGPGWVNLAPASPGQLMSPGPGKARKRDNKDPREDEC", "length": 439, "header": "tr|A0A9J7GD03-1|A0A9J7GD03_CRIGR Isoform 1 of Septin-9 OS=Cricetulus griseus OX=10029 GN=Septin12 PE=3 SV=1 CANONICAL=A0A9J7GD03-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771793", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771793", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD03", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GD03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD03" }, { "id": "PS51719", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51719" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Septin-type G", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 397, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 396, "end_pos": 398 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { 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{ "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GD12-1", "uniprot_ac": "A0A9J7GD12", "uniprot_id": "A0A9J7GD12_CRIGR", "mass": { "chemical_mass": 53407.0, "monoisotopic_mass": 53407.0 }, "refseq": { "ac": "XP_007642408", "name": "notchless protein homolog 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642408" }, "gene_names": [ { "name": "Nle1", "type": "recommended", "evidence": [ { "id": "A0A9J7GD12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12" } ] }, { "name": "Nle1", "type": "synonym", "evidence": [ { "id": "XP_007642408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642408" } ] } ], "protein_names": [ { "name": "Notchless protein homolog 1", "type": "recommended", "evidence": [ { "id": "A0A9J7GD12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12/entry#names_and_taxonomy" } ] }, { "name": "notchless protein homolog 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007642408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642408" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007642408", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642408" } ] }, { "annotation": "Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12#function" }, { "database": "UniProtKB", "id": "ARBA00054506", "url": "https://www.uniprot.org/uniprotkb/ARBA00054506#function" }, { "database": "UniProtKB", "id": "A0A8C2LPZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPZ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nle1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12", "locus": {} } ], "crossref": [ { "id": "A0A9J7GD12", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GD12", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774821", "url": "https://www.ncbi.nlm.nih.gov/gene/100774821", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774821", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774821", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LPZ9", "url": "https://www.orthodb.org/?gene=A0A8C2LPZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GD12", "url": "https://www.orthodb.org/?gene=A0A9J7GD12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19848", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19848", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19848:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19848:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08154", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08154", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007642408", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642408", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LPZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LPZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD12-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADAVAVGDEAAAGDVQRLLVQFQDEGGQVLGSPFDVPVDITPDKLQLVCNALLAQEEPLPLAFYVHDAEIVSSLGKTLESQSVETEKIIDIIYQPQAIFRVRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGMQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLKGSLKELKERASRRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR", "length": 487, "header": "tr|A0A9J7GD12-1|A0A9J7GD12_CRIGR Isoform 1 of Notchless protein homolog 1 OS=Cricetulus griseus OX=10029 GN=Nle1 PE=4 SV=1 CANONICAL=A0A9J7GD12-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LPZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12/entry#A0A8C2LPZ9-1", "sequence": { "sequence": "MADAVADEAAAGDVQRLLVQFQDEGGQVLGSPFDVPVDITPDKLQLVCNALLAQEEPLPLAFYVHDAEIVSSLGKTLESQSVETEKIIDIIYQPQAIFRVRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGMQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLKGSLKELKERASRRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR", "length": 485, "header": "tr|A0A8C2LPZ9-1|A0A8C2LPZ9_CRIGR Computationally mapped isoform of Notchless protein homolog 1 OS=Cricetulus griseus OX=10029 GN=Nle1 PE=4 SV=1 CANONICAL=A0A9J7GD12-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GD12-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12/entry#A0A9J7GD12-1", "sequence": { "sequence": "MADAVAVGDEAAAGDVQRLLVQFQDEGGQVLGSPFDVPVDITPDKLQLVCNALLAQEEPLPLAFYVHDAEIVSSLGKTLESQSVETEKIIDIIYQPQAIFRVRAVTRCTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGMQVGRTLTGHSKWITGLSWEPLHMNPECRYVASSSKDGSVRVWDTTAGRCERILTGHTQSVTCLRWGGDGLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEATVNAQDLKGSLKELKERASRRYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLARMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLATDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIWRR", "length": 487, "header": "tr|A0A9J7GD12-1|A0A9J7GD12_CRIGR Isoform 1 of Notchless protein homolog 1 OS=Cricetulus griseus OX=10029 GN=Nle1 PE=4 SV=1 CANONICAL=A0A9J7GD12-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 106, "start_aa": "Thr", "end_pos": 106, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr106", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774821", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774821", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12" } ], "pmid": "" }, { "name": "ribosomal large subunit assembly", "id": "GO:0000027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000027", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GD12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD12" }, { "id": "PF08154", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08154" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NLE", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 79, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 106 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GD13-1", "uniprot_ac": "A0A9J7GD13", "uniprot_id": "A0A9J7GD13_CRIGR", "mass": { "chemical_mass": 167852.0, "monoisotopic_mass": 167852.0 }, "refseq": { "ac": "XP_027281023", "name": "slit homolog 3 protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281023" }, "gene_names": [ { "name": "Slit3", "type": "recommended", "evidence": [ { "id": "A0A9J7GD13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13" } ] }, { "name": "Slit3", "type": "synonym", "evidence": [ { "id": "XP_027281023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281023" } ] } ], "protein_names": [ { "name": "Slit homolog 3 protein", "type": "recommended", "evidence": [ { "id": "A0A9J7GD13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13/entry#names_and_taxonomy" } ] }, { "name": "slit homolog 3 protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027281023", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281023" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281023" } ] }, { "annotation": "May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13#function" }, { "database": "UniProtKB", "id": "ARBA00053903", "url": "https://www.uniprot.org/uniprotkb/ARBA00053903#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slit3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13", "locus": {} } ], "crossref": [ { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766846", "url": "https://www.ncbi.nlm.nih.gov/gene/100766846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766846", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766846", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GD13", "url": "https://www.orthodb.org/?gene=A0A9J7GD13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45836", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45836", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45836:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45836:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01463", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01463", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281023", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281023", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GD13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD13-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPGRTWAGAAVRARLALALALASVLSGAPAAACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSIIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPGPHAEAPSCNANSLSCPSACTCSNNIVDCRGKGLTEIPTNLPESIVEIRLEQNAIKSIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTVSKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRNRFGSECFMDLVCPEKCRCEGTIVDCSNQKLARIPSHLPEYTTDLRLNDNDISVLEATGIFKKLPNLRKINLSNNRIKEVREGAFDGAAGVQELMLTGNQLETMHGRMFRGLSGLKTLMLRSNLISCVNNDTFTGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGRWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCVETVVRCSNRGLRALPKGMPKDVTELYLEGNHLTSVPKELSALRQLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPESMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTCSQDPVEQYRCTCPYSYKGKDCTMPINTCIQNPCQHGGTCHLSENHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGVNNYACVCPPNYTGELCDEVIDYCVPEMNLCQHEAKCISLDKGFRCECVPGYSGKLCETDNDDCATHKCRHGAQCVDAVNGYTCICPQGFSGLFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFIGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVMLNQTLNLVVDKGAPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGADRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCRHGLCRSVEKDSVVCECHPGWTGPLCDQEARDPCLGHSCSHGKCVATGSTYMCKCAEGYGGALCDHKNDSANACSAFKCHHGQCHISDHGDPYCLCQPGFSGNHCEQENPCLGEIVREAIRRQKDYASCATASKVPIMECRGGCGSQCCQPIRSKRRKYVFQCTDGSSFVEEVERHLECGCRACS", "length": 1523, "header": "tr|A0A9J7GD13-1|A0A9J7GD13_CRIGR Isoform 1 of Slit homolog 3 protein OS=Cricetulus griseus OX=10029 GN=Slit3 PE=4 SV=1 CANONICAL=A0A9J7GD13-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GD13-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13/entry#A0A9J7GD13-1", "sequence": { "sequence": "MAPGRTWAGAAVRARLALALALASVLSGAPAAACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSIIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPGPHAEAPSCNANSLSCPSACTCSNNIVDCRGKGLTEIPTNLPESIVEIRLEQNAIKSIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTVSKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRNRFGSECFMDLVCPEKCRCEGTIVDCSNQKLARIPSHLPEYTTDLRLNDNDISVLEATGIFKKLPNLRKINLSNNRIKEVREGAFDGAAGVQELMLTGNQLETMHGRMFRGLSGLKTLMLRSNLISCVNNDTFTGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGRWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCVETVVRCSNRGLRALPKGMPKDVTELYLEGNHLTSVPKELSALRQLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPESMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTCSQDPVEQYRCTCPYSYKGKDCTMPINTCIQNPCQHGGTCHLSENHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGVNNYACVCPPNYTGELCDEVIDYCVPEMNLCQHEAKCISLDKGFRCECVPGYSGKLCETDNDDCATHKCRHGAQCVDAVNGYTCICPQGFSGLFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFIGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVMLNQTLNLVVDKGAPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGADRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCRHGLCRSVEKDSVVCECHPGWTGPLCDQEARDPCLGHSCSHGKCVATGSTYMCKCAEGYGGALCDHKNDSANACSAFKCHHGQCHISDHGDPYCLCQPGFSGNHCEQENPCLGEIVREAIRRQKDYASCATASKVPIMECRGGCGSQCCQPIRSKRRKYVFQCTDGSSFVEEVERHLECGCRACS", "length": 1523, "header": "tr|A0A9J7GD13-1|A0A9J7GD13_CRIGR Isoform 1 of Slit homolog 3 protein OS=Cricetulus griseus OX=10029 GN=Slit3 PE=4 SV=1 CANONICAL=A0A9J7GD13-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13" } ], "pmid": "" }, { "name": "Roundabout binding", "id": "GO:0048495", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048495", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative chemotaxis", "id": "GO:0050919", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050919", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD13" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": 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{ "id": "A0A9J7GD27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD27" } ] }, { "name": "Wrap53", "type": "synonym", "evidence": [ { "id": "XP_027282827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282827" } ] } ], "protein_names": [ { "name": "Telomerase Cajal body protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7GD27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD27/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 79", "type": "synonym", "evidence": [ { "id": "A0A9J7GD27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD27/entry#names_and_taxonomy" } ] }, { "name": "WD40 repeat-containing protein antisense to TP53 gene homolog", "type": "synonym", "evidence": [ { "id": "A0A9J7GD27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD27/entry#names_and_taxonomy" } ] }, { "name": "telomerase Cajal body protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027282827", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282827" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282827" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD27", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD27" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wrap53", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD27", "locus": {} } ], "crossref": [ { "id": "A0A9J7GD27", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GD27", "database": "AlphaFoldDB", "categories": [] }, { "id": "100757087", "url": "https://www.ncbi.nlm.nih.gov/gene/100757087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", 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Classification" ] }, { "id": "PTHR13211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13211:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13211:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282827", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282827", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GD27", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD27-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GI66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GI66-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGESPYPSIPRETAGTKLDSRHDKMKTSEERLLVPDSLSSDQAPAPVPQGTPVDENTDSEPVPPPCGGDDRPQVATDSVAGSVVFQDPQQGDLVPPSAPLEVGFNTPGESSPRIEEQELSENASLPVTETNRPELESGEAVEDVSEEPGQVDEGDTFWTYSFSQVPRYLSGSWSEFSTHSENFLKGCKWAPDGSCILTNSADNTLRIYNLPPELYSEAEQVDYAEMVPVLRMVEGDTIYDYCWYSLMSSSQPDTSYVASSSRENPVHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTSRPGRDCEVRATFAKKQGQSGIISCIAFSPSQPLYACGSYGRTLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNLFFSGARKDAELLCWDLRQPGHLLWSLSREVTTNQRIYFDLDPSGQFLVSGNTNGMVSVWDINGAVSDSKLGPVMTFLPQKDCTNGVSLHPSLPLLATASGQRMFPEPTNSGDEGEPEGDLPLLSLCHAHPEWRLQLWWCGGGPDPSSPNDHQDEKGQGRTEGCGDELI", "length": 562, "header": "tr|A0A9J7GD27-1|A0A9J7GD27_CRIGR Isoform 1 of Telomerase Cajal body protein 1 OS=Cricetulus griseus OX=10029 GN=Wrap53 PE=3 SV=1 CANONICAL=A0A9J7GD27-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GD27-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD27/entry#A0A9J7GD27-1", "sequence": { "sequence": "MGGESPYPSIPRETAGTKLDSRHDKMKTSEERLLVPDSLSSDQAPAPVPQGTPVDENTDSEPVPPPCGGDDRPQVATDSVAGSVVFQDPQQGDLVPPSAPLEVGFNTPGESSPRIEEQELSENASLPVTETNRPELESGEAVEDVSEEPGQVDEGDTFWTYSFSQVPRYLSGSWSEFSTHSENFLKGCKWAPDGSCILTNSADNTLRIYNLPPELYSEAEQVDYAEMVPVLRMVEGDTIYDYCWYSLMSSSQPDTSYVASSSRENPVHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTSRPGRDCEVRATFAKKQGQSGIISCIAFSPSQPLYACGSYGRTLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNLFFSGARKDAELLCWDLRQPGHLLWSLSREVTTNQRIYFDLDPSGQFLVSGNTNGMVSVWDINGAVSDSKLGPVMTFLPQKDCTNGVSLHPSLPLLATASGQRMFPEPTNSGDEGEPEGDLPLLSLCHAHPEWRLQLWWCGGGPDPSSPNDHQDEKGQGRTEGCGDELI", "length": 562, "header": "tr|A0A9J7GD27-1|A0A9J7GD27_CRIGR Isoform 1 of Telomerase Cajal body protein 1 OS=Cricetulus griseus OX=10029 GN=Wrap53 PE=3 SV=1 CANONICAL=A0A9J7GD27-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GI66-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD27/entry#A0A9J7GI66-1", "sequence": { 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"monoisotopic_mass": 29680.0 }, "refseq": { "ac": "XP_027279052", "name": "LOW QUALITY PROTEIN: seminal vesicle secretory protein 3A isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279052" }, "gene_names": [ { "name": "LOC100763783", "type": "recommended", "evidence": [ { "id": "A0A9J7GD30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD30" } ] }, { "name": "LOC100763783", "type": "synonym", "evidence": [ { "id": "XP_027279052", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279052" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: seminal vesicle secretory protein 3A isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027279052", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279052" }, { "id": "A0A9J7GD30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD30/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279052" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD30", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD30" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100763783", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD30", "locus": {} } ], "crossref": [ { "id": "A0A9J7GD30", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GD30", "database": "AlphaFoldDB", "categories": [] }, { "id": "100763783", "url": "https://www.ncbi.nlm.nih.gov/gene/100763783", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763783", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763783", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GD30", "url": "https://www.orthodb.org/?gene=A0A9J7GD30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10547", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10547", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10547:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10547:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279052", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GD30", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD30-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSIFFSLSLLLLLGKQAAGIGTYGGPKGHFLVRTPPVVFIQKGHFHYGPSEEQEAASEESVFTQTKQHAYGQDADAEARETQSSQEQTDLNEDIDCDEEDEISQQKSQLQSQSQIKSQAQLRSQEAQLKSQTGQRKTLGQVIAQVKLKSHSAPLKPYQAPLTLQKVSAQQIKGKEYALDEDLARVRQQDKKVHKLKRNLGWARKTAENLPHLRQHSQGYDGYVMQFQEQLQGGIHHTKSLHQAQGMCYCPKGGLFLHQEVFAE", "length": 264, "header": "tr|A0A9J7GD30-1|A0A9J7GD30_CRIGR Isoform 1 of LOW QUALITY PROTEIN: seminal vesicle secretory protein 3A isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100763783 PE=3 SV=1 CANONICAL=A0A9J7GD30-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GD30-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD30/entry#A0A9J7GD30-1", "sequence": { "sequence": "MKSIFFSLSLLLLLGKQAAGIGTYGGPKGHFLVRTPPVVFIQKGHFHYGPSEEQEAASEESVFTQTKQHAYGQDADAEARETQSSQEQTDLNEDIDCDEEDEISQQKSQLQSQSQIKSQAQLRSQEAQLKSQTGQRKTLGQVIAQVKLKSHSAPLKPYQAPLTLQKVSAQQIKGKEYALDEDLARVRQQDKKVHKLKRNLGWARKTAENLPHLRQHSQGYDGYVMQFQEQLQGGIHHTKSLHQAQGMCYCPKGGLFLHQEVFAE", "length": 264, "header": "tr|A0A9J7GD30-1|A0A9J7GD30_CRIGR Isoform 1 of LOW QUALITY PROTEIN: seminal vesicle secretory protein 3A isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100763783 PE=3 SV=1 CANONICAL=A0A9J7GD30-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281062" } ] }, { "annotation": "Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1. Once recruited, dephosphorylates 19S component PSMC2/RPT1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly. Has also been reported to stimulate the proteolytic activity of the 26S proteasome.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33#function" }, { "database": "UniProtKB", "id": "ARBA00046190", "url": "https://www.uniprot.org/uniprotkb/ARBA00046190#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ublcp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33", "locus": {} } ], "crossref": [ { "id": "cd01813", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01813", "database": "CDD", "categories": [ "Protein Classification" ] 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"Protein Classification" ] }, { "id": "IPR051658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762523", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762523", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GD33", "url": "https://www.orthodb.org/?gene=A0A9J7GD33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48493", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48493", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48493:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48493:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281062", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20629", "url": "https://www.rhea-db.org/rhea/20629", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "47004", "url": "https://www.rhea-db.org/rhea/47004", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GD33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD33-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GFV7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GFV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLCPPPDNDDVINDFDIEDEIVEVENREENLLKISRRVKEYKVEVLNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELVKLTQYLKEIAKLDDFLELNHKYWERYLSKKQGQ", "length": 318, "header": "tr|A0A9J7GD33-1|A0A9J7GD33_CRIGR Isoform 1 of Ubiquitin-like domain-containing CTD phosphatase 1 OS=Cricetulus griseus OX=10029 GN=Ublcp1 PE=4 SV=1 CANONICAL=A0A9J7GD33-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GD33-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33/entry#A0A9J7GD33-1", "sequence": { "sequence": 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Computationally mapped isoform of Ubiquitin-like domain-containing CTD phosphatase 1 OS=Cricetulus griseus OX=10029 GN=Ublcp1 PE=4 SV=1 CANONICAL=A0A9J7GD33-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762523", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762523", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase activity", "id": "GO:0004722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004722", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of proteasome assembly", "id": "GO:0090364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090364", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20629", "name": "", "equation": "O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "G3I434-1", "G3H622-1", "G3HKY7-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HVT3-1", "A0A061HX98-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A8C2QCP2-1", "A0A8C2LTP5-1", "A0A8C2N2E5-1", "A0A8C2QBZ1-1", "A0A3L7HBF4-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JYW1-1", "A0A3L7I513-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "20629", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20629" } ] }, { "id": "47004", "name": "", "equation": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GV48-1", "G3GWQ6-1", "G3H060-1", "G3H9Q0-1", "G3H622-1", "G3HKY7-1", "G3H7Z6-1", "G3I157-1", "G3HCQ6-1", "A0A8C2MA30-1", "G3HMJ7-1", "A0A8C2MF90-1", "A0A9J7GX39-1", "G3I434-1", "G3GRD1-1", "G3I4H5-1", "G3H8H2-1", "A0A9J7F890-1", "A0A8C2MW37-1", "A0A061I6V7-1", "A0A9J7GBP5-1", "A0A9J7JFN8-1", "A0A9J7G7W0-1", "A0A9J7GE78-1", "A0A061HX98-1", "A0A3L7HEJ5-1", "A0A3L7HX32-1", "A0A8C2LYQ8-1", "A0A8C2M5N0-1", "A0A9J7JBH1-1", "A0A8C2ME51-1", "A0A8C2MTQ0-1", "A0A3L7IJ01-1", "A0A9J7EY47-1", "A0A8C2LGL9-1", "A0A8C2LVB9-1", "A0A8C2QH88-1", "A0A9J7F130-1", "A0A9J7FMB0-1", "A0A9J7FWJ6-1", "A0A9J7FXD0-1", "A0A9J7G243-1", "A0A9J7GEM4-1", "A0A9J7G1B8-1", "A0A9J7K1J8-1", "A0A9J7K5S1-1", "A0A9J7EZL1-1", "A0A9J7F6Q7-1", "A0A8C2N2E5-1", "A0A8C2LTP5-1", "A0A8C2QBZ1-1", "A0A8C2QCP2-1", "A0A3L7HBF4-1", "A0A3L7HC66-1", "A0A9J7GK96-1", "A0A8C2LI03-1", "A0A9J7G0U7-1", "A0A9J7GD33-1", "A0A9J7H9S5-1", "A0A9J7HCJ8-1", "A0A9J7GJY7-1", "A0A9J7JXQ8-1", "A0A9J7JYW1-1", "A0A9J7FKB3-1", "A0A8C2LGY1-1", "A0A3L7HEM4-1" ], "evidence": [ { "id": "47004", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/47004" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HVT3", "gene_name": "Ppm1k", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + H2O = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate.", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] }, { "ec_number": "3.1.3.52", "activity": "", "evidence": [ { "id": "A0A061HVT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVT3" } ] } ] }, { "uniprot_ac": "A0A061HX98", "gene_name": "Dusp9", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A061HX98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HX98" } ] } ] }, { "uniprot_ac": "A0A061I6V7", "gene_name": "Pgam5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A061I6V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6V7" } ] } ] }, { "uniprot_ac": "A0A3L7HBF4", "gene_name": "Cpped1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HBF4" } ] } ] }, { "uniprot_ac": "A0A3L7HC66", "gene_name": "Ppp6c", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HC66" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7HEM4", "gene_name": "Ctdspl2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEM4" } ] } ] }, { "uniprot_ac": "A0A3L7HX32", "gene_name": "Dusp8", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HX32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HX32" } ] } ] }, { "uniprot_ac": "A0A3L7I513", "gene_name": "Pdxp", "activity": [ { "ec_number": "3.1.3.74", "activity": "pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.74", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7I513", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I513" } ] } ] }, { "uniprot_ac": "A0A3L7IJ01", "gene_name": "Ppp2cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7IJ01", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJ01" } ] } ] }, { "uniprot_ac": "A0A8C2LGL9", "gene_name": "Ppp1cb", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGL9" } ] } ] }, { "uniprot_ac": "A0A8C2LGY1", "gene_name": "Ppp1ca", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGY1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LGY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGY1" } ] } ] }, { "uniprot_ac": "A0A8C2LI03", "gene_name": "Ctdsp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LI03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI03" } ] } ] }, { "uniprot_ac": "A0A8C2LTP5", "gene_name": "LOC100752571", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LTP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTP5" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYQ8", "gene_name": "Ppm1l", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYQ8" } ] } ] }, { "uniprot_ac": "A0A8C2M5N0", "gene_name": "Ppp1cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2M5N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5N0" } ] } ] }, { "uniprot_ac": "A0A8C2MA30", "gene_name": "Phlpp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MA30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MA30" } ] } ] }, { "uniprot_ac": "A0A8C2ME51", "gene_name": "Ppm1g", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2ME51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ME51" } ] } ] }, { "uniprot_ac": "A0A8C2MF90", "gene_name": "Ssh2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MF90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MF90" } ] } ] }, { "uniprot_ac": "A0A8C2MTQ0", "gene_name": "Ssh1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MTQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTQ0" } ] } ] }, { "uniprot_ac": "A0A8C2MW37", "gene_name": "Ppp3cc", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2MW37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MW37" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": 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H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F6Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F6Q7" } ] } ] }, { "uniprot_ac": "A0A9J7F890", "gene_name": "Ctdsp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7F890", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F890" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G1B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B8" } ] } ] }, { "uniprot_ac": "A0A9J7G243", "gene_name": "Ppm1a", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7G243", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G243" } ] } ] }, { "uniprot_ac": "A0A9J7G7W0", "gene_name": "Ptpmt1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7W0", "database": "UniProtKB", "url": 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"ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GBP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBP5" } ] } ] }, { "uniprot_ac": "A0A9J7GD33", "gene_name": "Ublcp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GD33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD33" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": 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"https://www.uniprot.org/uniprotkb/A0A9J7GD64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD64-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPJ6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METLLLGAGLLLGAYVLVYYNLVKAPPCGGIGSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAVFDLRQESGNNEVIFMALDLASLASVQAFATAFLSSEPRLDILIHNAGISSCGRTRETFNLLLRVNHVGPFLLTHLLLPRLKSCAPSRVVVVSSAAHRRGRLDFTRLDCPVVGWQQELRAYADSKLANVLFARELANQLEGTGVTCYAAHPGPVNSELFLRHLPGWLCPILRPLAWLLLRAPQGGAQTPLYCALQEGIEPLSGRYFANCRVEEVSPAARDDQAAHRLWKATKKLAGLGPGEDDDDPEEEPQPQGPRALSSLSAPYPEKTTVSGLSHSCPGSPDLSKLTQRRIQMKARPLPD", "length": 377, "header": "tr|A0A9J7GD64-1|A0A9J7GD64_CRIGR Isoform 1 of Dehydrogenase/reductase SDR family member 13 OS=Cricetulus griseus OX=10029 GN=Dhrs13 PE=3 SV=1 CANONICAL=A0A9J7GD64-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GD64-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD64/entry#A0A9J7GD64-1", "sequence": { "sequence": "METLLLGAGLLLGAYVLVYYNLVKAPPCGGIGSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAVFDLRQESGNNEVIFMALDLASLASVQAFATAFLSSEPRLDILIHNAGISSCGRTRETFNLLLRVNHVGPFLLTHLLLPRLKSCAPSRVVVVSSAAHRRGRLDFTRLDCPVVGWQQELRAYADSKLANVLFARELANQLEGTGVTCYAAHPGPVNSELFLRHLPGWLCPILRPLAWLLLRAPQGGAQTPLYCALQEGIEPLSGRYFANCRVEEVSPAARDDQAAHRLWKATKKLAGLGPGEDDDDPEEEPQPQGPRALSSLSAPYPEKTTVSGLSHSCPGSPDLSKLTQRRIQMKARPLPD", "length": 377, "header": "tr|A0A9J7GD64-1|A0A9J7GD64_CRIGR Isoform 1 of Dehydrogenase/reductase SDR family member 13 OS=Cricetulus griseus OX=10029 GN=Dhrs13 PE=3 SV=1 CANONICAL=A0A9J7GD64-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD64/entry#A0A9J7JPJ6-1", "sequence": { "sequence": "METLLLGAGLLLGAYVLVYYNLVKAPPCGGIGSLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAVFDLRQESGNNEVIFMALDLASLASVQAFATAFLSSEPRLDILIHNAGISSCGRTRETFNLLLRVNHVGPFLLTHLLLPRLKSCAPSRVVVVSSAAHRRGRLDFTRLDCPVVGWQQELRAYADSKLANVLFARELANQLEGTGVTCYAAHPDVKCKPPSQAETLGFITNTIKKSYSGDSDKLPFSQGVVSLTCELRTLPASPSWMAVSYFAPTGLATTPGTSRGCPDTPVLCSAGGH", "length": 313, "header": "tr|A0A9J7JPJ6-1|A0A9J7JPJ6_CRIGR Computationally mapped isoform of Dehydrogenase/reductase SDR family member 13 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dhrs13 PE=3 SV=1 CANONICAL=A0A9J7GD64-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD64" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD64" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767705", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767705", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RNA5-1", "protein_name": "Dehydrogenase/reductase SDR family member 13", "gene_name": "DHRS13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEALLLGVGLLLGAYVLVYYNLVKAPPCRGIASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLRVNHVGPFLLTHLLLPRLKTCAPSRVVVVSSAAHRRGRLDFTRLDRPVVGWRQELRAYADSKLANVLFTRELATQLEGTGVTCYAAHPGPVNSELFLRHVPRWLRPLLCPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLEPGEDAESDEEPQPVDPGVPSSLSSPHPEEPAASEPYTSPQSSPDLSKVTRRIPVKAEPEPQAS", "length": 377 }, "evidence": [ { "id": "A0A9J7GD64", "url": "https://omabrowser.org/oma/group/A0A9J7GD64/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q17QU7-1", "protein_name": "Dehydrogenase/reductase SDR family member 13", "gene_name": "DHRS13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEALLLGVGLLLGAYVLVYYNLVKAPPCRGLASLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREPFNLLLRVNHIGPFLLTHLLLPRLKTSAPSRVVVVSSAAHRRGRLDFTRLDHPVVGWQQELRAYANSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASRKLAGLGPGEDAESDEDSQPEDPGTPSSPSSPHPEEPTVSELYPSPQSSTDRSTVTCRIPVKAELEPQAC", "length": 377 }, "evidence": [ { "id": "A0A9J7GD64", "url": "https://omabrowser.org/oma/group/A0A9J7GD64/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54I93-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGLDENEIINNDCNIGNDNNNNSNIILNRQLVVIVTGSSDGLGKVVSGMLAKTNYFVILANRDLIKAKLVLDEILSTTPNNKNVISMKLDLSSFDSIKEFVNQFEKLNLQLDVLINNAGIYTPPFSLPEGFESQLMVNHLGPFLLTNLLINKFTENARIINLSSIAHKNSEIFNVEDLSCKSIDSYNAIKRYSNSKLYAILFTKELNRIFKKNNSKIIALSLHPGVISTTNLFKNIPNYIKLLLTISKPFTTTINTASTAIYRLAVGADPELPLLTGGEYFNINVLVDPIPQALSQENWRLLWAKSCEYCKIDDIGK", "length": 317 }, "evidence": [ { "id": "A0A9J7GD64", "url": "https://omabrowser.org/oma/group/A0A9J7GD64/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5SS80-1", "protein_name": "Dehydrogenase/reductase SDR family member 13", "gene_name": "Dhrs13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLLLGAGLLLGAYVLVYYNLVKAPSCGGIGSLRGRTVVVTGANSGIGKMTALELARRGARVVLACRSRERGEAAAFDLRQESGNNEVIFMALDLASLASVQAFATAFLSSEPRLDVLIHNAGISSCGRTRETFNLLLRVNHVGPFLLTHLLLPRLRSCAPSRVVIVSSAAHRRGRLDFTRLDCPVVGWQQELRAYADSKLANVLFARELATQLEGTGVTCYAAHPGPVNSELFLRHLPGWLRPILRPLAWLVLRAPQGGAQTPLYCALQEGIEPLSGRYFANCHVEEVSPAARDDQAAQRLWKATKKLAGLAPGDDDDDPDEEPEPEDPRAPSSQSAPSPEKTTVSGPSHSYQGSQDLSKLTQRRIQVKDEPTP", "length": 376 }, "evidence": [ { "id": "A0A9J7GD64", "url": "https://omabrowser.org/oma/group/A0A9J7GD64/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UX07-1", "protein_name": "Dehydrogenase/reductase SDR family member 13", "gene_name": "DHRS13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEALLLGAGLLLGAYVLVYYNLVKAPPCGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASKRLAGLGPGEDAEPDEDPQSEDSEAPSSLSTPHPEEPTVSQPYPSPQSSPDLSKMTHRIQAKVEPEIQLS", "length": 377 }, "evidence": [ { "id": "A0A9J7GD64", "url": "https://omabrowser.org/oma/group/A0A9J7GD64/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD64" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GD65-1", "uniprot_ac": "A0A9J7GD65", "uniprot_id": "A0A9J7GD65_CRIGR", "mass": { "chemical_mass": 9419.0, "monoisotopic_mass": 9419.0 }, "refseq": { "ac": "XP_003506132", "name": "40S ribosomal protein S27-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506132" }, "gene_names": [ { "name": "LOC100755284", "type": "recommended", "evidence": [ { "id": "A0A9J7GD65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD65" } ] }, { "name": "LOC100755284", "type": "synonym", "evidence": [ { "id": "XP_003506132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506132" } ] } ], "protein_names": [ { "name": "40S ribosomal protein S27-like", "type": "synonym", "evidence": [ { "id": "XP_003506132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506132" }, { "id": "A0A9J7GD65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD65/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614210.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003506132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506132" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD65", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD65" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100755284", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD65", "locus": {} } ], "crossref": [ { "id": "A0A9J7GD65", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GD65", "database": "AlphaFoldDB", "categories": [] }, { "id": "100755284", "url": "https://www.ncbi.nlm.nih.gov/gene/100755284", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000592", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000592", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755284", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755284", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GD65", "url": "https://www.orthodb.org/?gene=A0A9J7GD65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11594", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11594", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01667", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01667", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003506132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506132", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GD65", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD65-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLEKDLLHPSPEAEKRKHKKKHPVQSPNSSFMDVKCPGRYKIITVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "length": 84, "header": "tr|A0A9J7GD65-1|A0A9J7GD65_CRIGR Isoform 1 of 40S ribosomal protein S27-like OS=Cricetulus griseus OX=10029 GN=LOC100755284 PE=3 SV=1 CANONICAL=A0A9J7GD65-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GD65-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD65/entry#A0A9J7GD65-1", "sequence": { "sequence": "MTLEKDLLHPSPEAEKRKHKKKHPVQSPNSSFMDVKCPGRYKIITVFSHAQTVVLCVGCSTVLCQPTGGKARLTEGCSFRRKQH", "length": 84, "header": "tr|A0A9J7GD65-1|A0A9J7GD65_CRIGR Isoform 1 of 40S ribosomal protein S27-like OS=Cricetulus griseus OX=10029 GN=LOC100755284 PE=3 SV=1 CANONICAL=A0A9J7GD65-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD65", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD65" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"A0A9J7GD91", "uniprot_id": "A0A9J7GD91_CRIGR", "mass": { "chemical_mass": 67273.0, "monoisotopic_mass": 67273.0 }, "refseq": { "ac": "XP_027279917", "name": "male-specific lethal 1 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279917" }, "gene_names": [ { "name": "Msl1", "type": "recommended", "evidence": [ { "id": "A0A9J7GD91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91" } ] }, { "name": "Msl1", "type": "synonym", "evidence": [ { "id": "XP_027279917", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279917" } ] } ], "protein_names": [ { "name": "Male-specific lethal 1 homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7GD91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91/entry#names_and_taxonomy" } ] }, { "name": "Male-specific lethal 1-like 1", "type": "synonym", "evidence": [ { "id": "A0A9J7GD91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91/entry#names_and_taxonomy" } ] }, { "name": "male-specific lethal 1 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027279917", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279917" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279917", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279917" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Msl1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91", "locus": {} } ], "crossref": [ { "id": "A0A9J7GD91", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GD91", "database": "AlphaFoldDB", "categories": [] }, { "id": "100773452", "url": "https://www.ncbi.nlm.nih.gov/gene/100773452", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026711", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026711", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773452", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773452", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GD91", "url": "https://www.orthodb.org/?gene=A0A9J7GD91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21656:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21656:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15275", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15275", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279917", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279917", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GD91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GD91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JWZ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JWZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTMRSAVFKAAAAPAGGNPEQRLDYERAAALGGPEDESGAAEAHFLPRHRKLKEPGPPLASSQGGSPAPSPAGCGGKGRGLLLPAGAAPGQQEESWGGSVPLPCPPPATKQAGIGGEPVAAGAGCSPRPKYQAVLPIQTGSLVAAAKEPTPWAGDKGGAAPPAATASDPAGPPPLPLPGPPPLAPTATAGTLAASEGRWKSMRKSPLGGGGGSGASSQAACLKQILLLQLDLIEQQQQQLQAKEKEIEELKSERDTLLARIERMERRMQLVKRDNEKERHKLFQGYETEEREETELSEKIKLERQPELCETSQALPSKPFSCGRSGKGHKRKTPFGNTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSAHPKEKTFSSEMEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDILENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKGIQESEPEVTSFFPEPDDVESLMITPFLPVVAFGRPLPKLTPQNFELPWLDERSRCRLEIQKKQTPHRTCRK", "length": 614, "header": "tr|A0A9J7GD91-1|A0A9J7GD91_CRIGR Isoform 1 of Male-specific lethal 1 homolog OS=Cricetulus griseus OX=10029 GN=Msl1 PE=3 SV=1 CANONICAL=A0A9J7GD91-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GD91-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91/entry#A0A9J7GD91-1", "sequence": { "sequence": "MTMRSAVFKAAAAPAGGNPEQRLDYERAAALGGPEDESGAAEAHFLPRHRKLKEPGPPLASSQGGSPAPSPAGCGGKGRGLLLPAGAAPGQQEESWGGSVPLPCPPPATKQAGIGGEPVAAGAGCSPRPKYQAVLPIQTGSLVAAAKEPTPWAGDKGGAAPPAATASDPAGPPPLPLPGPPPLAPTATAGTLAASEGRWKSMRKSPLGGGGGSGASSQAACLKQILLLQLDLIEQQQQQLQAKEKEIEELKSERDTLLARIERMERRMQLVKRDNEKERHKLFQGYETEEREETELSEKIKLERQPELCETSQALPSKPFSCGRSGKGHKRKTPFGNTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSAHPKEKTFSSEMEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVARCLMPSSVAGETSVLAVPSWRDHSVEPLRDPNPSDILENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKGIQESEPEVTSFFPEPDDVESLMITPFLPVVAFGRPLPKLTPQNFELPWLDERSRCRLEIQKKQTPHRTCRK", "length": 614, "header": "tr|A0A9J7GD91-1|A0A9J7GD91_CRIGR Isoform 1 of Male-specific lethal 1 homolog OS=Cricetulus griseus OX=10029 GN=Msl1 PE=3 SV=1 CANONICAL=A0A9J7GD91-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JWZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91/entry#A0A9J7JWZ2-1", "sequence": { "sequence": "MTMRSAVFKAAAAPAGGNPEQRLDYERAAALGGPEDESGAAEAHFLPRHRKLKEPGPPLASSQGGSPAPSPAGCGGKGRGLLLPAGAAPGQQEESWGGSVPLPCPPPATKQAGIGGEPVAAGAGCSPRPKYQAVLPIQTGSLVAAAKEPTPWAGDKGGAAPPAATASDPAGPPPLPLPGPPPLAPTATAGTLAASEGRWKSMRKSPLGGGGGSGASSQAACLKQILLLQLDLIEQQQQQLQAKEKEIEELKSERDTLLARIERMERRMQLVKRDNEKERHKLFQGYETEEREETELSEKIKLERQPELCETSQALPSKPFSCGRSGKGHKRKTPFGNTERKTPVKKLAPEFSKVKTKTPKHSPIKEEPCGSLSETVCKRELRSQETPEKPRSSVDTPPRLSTPQKGPSAHPKEKTFSSEMEDLPYLSTTEMYLCRWHQPPPSPLPLRESSPKKEETVAIPSWRDHSVEPLRDPNPSDILENLDDSVFSKRHAKLELDEKRRKRWDIQRIREQRILQRLQLRMYKKKGIQESEPEVTSFFPEPDDVESLMITPFLPVVAFGRPLPKLTPQNFELPWLDERSRCRLEIQKKQTPHRTCRK", "length": 598, "header": "tr|A0A9J7JWZ2-1|A0A9J7JWZ2_CRIGR Computationally mapped isoform of Male-specific lethal 1 homolog OS=Cricetulus griseus OX=10029 GN=Msl1 PE=3 SV=1 CANONICAL=A0A9J7GD91-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773452", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773452", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91" } ], "pmid": "" }, { "name": "MSL complex", "id": "GO:0072487", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072487", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GD91", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": 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"authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDA7-1", "uniprot_ac": "A0A9J7GDA7", "uniprot_id": "A0A9J7GDA7_CRIGR", "mass": { "chemical_mass": 273630.0, "monoisotopic_mass": 273630.0 }, "refseq": { "ac": "XP_027282540", "name": "pre-mRNA-processing-splicing factor 8 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282540" }, "gene_names": [ { "name": "Prpf8", "type": "recommended", "evidence": [ { "id": "A0A9J7GDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7" } ] }, { "name": "Prpf8", "type": "synonym", "evidence": [ { "id": "XP_027282540", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282540" } ] } ], "protein_names": [ { "name": "Pre-mRNA-processing-splicing factor 8", "type": "recommended", "evidence": [ { "id": "A0A9J7GDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7/entry#names_and_taxonomy" } ] }, { "name": "Splicing factor Prp8", "type": "synonym", "evidence": [ { "id": "A0A9J7GDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7/entry#names_and_taxonomy" } ] }, { "name": "pre-mRNA-processing-splicing factor 8 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027282540", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282540" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282540", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282540" } ] }, { "annotation": "Plays a role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as a scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7#function" }, { "database": "UniProtKB", "id": "ARBA00055739", "url": "https://www.uniprot.org/uniprotkb/ARBA00055739#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prpf8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7", "locus": {} } ], "crossref": [ { "id": "cd08056", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08056", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13838", "url": 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"id": "PF01398", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01398", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08082", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08082", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10596", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10596", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10598", 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"MAGVFPYRGPGNPVPGPLAPLPDYMSEEKLQEKARKWQQLQAKRYAEKRKFGFVDAQKEDMPPEHVRKIIRDHGDMTNRKFRHDKRVYLGALKYMPHAVLKLLENMPMPWEQIRDVPVLYHITGAISFVNEIPWVIEPVYISQWGSMWIMMRREKRDRRHFKRMRFPPFDDEEPPLDYADNILDVEPLEAIQLELDPEEDAPVLDWFYDHQPLRDSRKYVNGSTYQRWQFTLPMMSTLYRLANQLLTDLVDDNYFYLFDLKAFFTSKALNMAIPGGPKFEPLVRDINLQDEDWNEFNDINKIIIRQPIRTEYKIAFPYLYNNLPHHVHLTWYHTPNVVFIKTEDPDLPAFYFDPLINPISHRHSVKSQEPLPDDDEEFELPEFVEPFLKDTPLYTDNTANGIALLWAPRPFNLRSGRTRRALDIPLVKNWYREHCPAGQPVKVRVSYQKLLKYYVLNALKHRPPKAQKKRYLFRSFKATKFFQSTKLDWVEVGLQVCRQGYNMLNLLIHRKNLNYLHLDYNFNLKPVKTLTTKERKKSRFGNAFHLCREVLRLTKLVVDSHVQYRLGNVDAFQLADGLQYIFAHVGQLTGMYRYKYKLMRQIRMCKDLKHLIYYRFNTGPVGKGPGCGFWAAGWRVWLFFMRGITPLLERWLGNLLARQFEGRHSKGVAKTVTKQRVESHFDLELRAAVMHDILDMMPEGIKQNKARTILQHLSEAWRCWKANIPWKVPGLPTPIENMILRYVKAKADWWTNTAHYNRERIRRGATVDKTVCKKNLGRLTRLYLKAEQERQHNYLKDGPYITAEEAVAVYTTTVHWLESRRFSPIPFPPLSYKHDTKLLILALERLKEAYSVKSRLNQSQREELGLIEQAYDNPHEALSRIKRHLLTQRAFKEVGIEFMDLYSHLVPVYDVEPLEKITDAYLDQYLWYEADKRRLFPPWIKPADTEPPPLLVYKWCQGINNLQDVWETSEGECNVMLESRFEKMYEKIDLTLLNRLLRLIVDHNIADYMTAKNNVVINYKDMNHTNSYGIIRGLQFASFIVQYYGLVMDLLVLGLHRASEMAGPPQMPNDFLSFQDIATEAAHPIRLFCRYIDRIHIFFRFTADEARDLIQRYLTEHPDPNNENIVGYNNKKCWPRDARMRLMKHDVNLGRAVFWDIKNRLPRSVTTVQWENSFVSVYSKDNPNLLFNMCGFECRILPKCRTSYEEFTHKDGVWNLQNEVTKERTAQCFLRVDDESMQRFHNRVRQILMASGSTTFTKIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPVVFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLTLEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTYFPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQKIHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSHDIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGSKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLSSQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPVEEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALHVNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTKEQSQLTATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLPSQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIIITCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNPKGYLPSHYERVQMLLSDRFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEFYHEVHRPSHFLNFALLQEGEVYSADREDLYA", "length": 2335, "header": "tr|A0A9J7GDA7-1|A0A9J7GDA7_CRIGR Isoform 1 of Pre-mRNA-processing-splicing factor 8 OS=Cricetulus griseus OX=10029 GN=Prpf8 PE=4 SV=1 CANONICAL=A0A9J7GDA7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:107976990", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107976990", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "pre-mRNA intronic binding", "id": "GO:0097157", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097157", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7" } ], "pmid": "" }, { "name": "U2 snRNA binding", "id": "GO:0030620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030620", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7" } ], "pmid": "" }, { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7" } ], "pmid": "" }, { "name": "U1 snRNA binding", "id": "GO:0030619", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7" } ], "pmid": "" }, { "name": "U6 snRNA binding", "id": "GO:0017070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017070", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDA7" } ], "pmid": "" }, { "name": "U5 snRNA binding", "id": "GO:0030623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030623", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDA7", "url": 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"A0A9J7GDC0-1", "uniprot_ac": "A0A9J7GDC0", "uniprot_id": "A0A9J7GDC0_CRIGR", "mass": { "chemical_mass": 9617.0, "monoisotopic_mass": 9617.0 }, "refseq": { "ac": "XP_003496386", "name": "40S ribosomal protein S27-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496386" }, "gene_names": [ { "name": "LOC100751121", "type": "recommended", "evidence": [ { "id": "A0A9J7GDC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDC0" } ] }, { "name": "LOC100751121", "type": "synonym", "evidence": [ { "id": "XP_003496386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496386" } ] } ], "protein_names": [ { "name": "40S ribosomal protein S27-like", "type": "synonym", "evidence": [ { "id": "XP_003496386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496386" }, { "id": "A0A9J7GDC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDC0/entry#names_and_taxonomy" } ] } ], 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This record is derived from a genomic sequence (NW_003613619.1) annotated using gene prediction method: Gnomon. 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] }, { "name": "Rab4-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A9J7GDE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283429", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283429" } ] }, { "annotation": "Activating adapter involved in cargo sorting from early/recycling endosomes. Regulates retrieval of proteins from endosomes to the trans-Golgi network through interaction with the dynein-dynactin complex. Dual effector of RAB4B and RAB14, mediates a cooperative interaction allowing endosomal tethering and fusion. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. In oocytes, self-assembles to form a protein matrix which hold together endolysosomes, autophagosomes and proteasomes and generate non-membrane-bound compartments called endo-lysosomal vesicular assemblies (ELVAs). In immature oocytes, ELVAs sequester ubiquitinated protein aggregates and degrade them upon oocyte maturation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE4#function" }, { "database": "UniProtKB", "id": "ARBA00055960", "url": "https://www.uniprot.org/uniprotkb/ARBA00055960#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rufy1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE4", "locus": {} } ], "crossref": [ { "id": "A0A9J7GDE4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GDE4", "database": "AlphaFoldDB", "categories": [] }, { 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Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282617", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282617" } ] }, { "annotation": "Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI[3]P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of clathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport. 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"length": 1169, "header": "tr|A0A9J7GDE8-1|A0A9J7GDE8_CRIGR Isoform 1 of Ankyrin repeat and FYVE domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ankfy1 PE=4 SV=1 CANONICAL=A0A9J7GDE8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757230", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757230", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE8" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 130, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7GDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDE8" }, { "id": "PS50178", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FYVE-type", "eco_id": "ECO_0000259", "start_pos": 1104, "end_pos": 1164, "start_aa": "Trp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 430, "end_pos": 432 }, { "start_pos": 505, "end_pos": 507 }, { "start_pos": 616, "end_pos": 618 }, { "start_pos": 737, "end_pos": 739 }, { "start_pos": 92, "end_pos": 94 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDG5-1", "uniprot_ac": "A0A9J7GDG5", "uniprot_id": "A0A9J7GDG5_CRIGR", "mass": { "chemical_mass": 147952.0, "monoisotopic_mass": 147952.0 }, "refseq": { "ac": "XP_027282668", "name": "NACHT, LRR and PYD domains-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282668" }, "gene_names": [ { "name": "Nlrp1", "type": "recommended", "evidence": [ { "id": "A0A9J7GDG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5" } ] }, { "name": "Nlrp1", "type": "synonym", "evidence": [ { "id": "XP_027282668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282668" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027282668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282668" }, { "id": "A0A9J7GDG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282668" } ] }, { "annotation": "Constitutes the active part of the Nlrp1a inflammasome. In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, N-terminus), preventing activation of the Nlrp1a inflammasome. In response to pathogen-associated signals, the N-terminal part of Nlrp1a is degraded by the proteasome, releasing this form, which polymerizes to form the Nlrp1a inflammasome complex: the Nlrp1a inflammasome complex then directly recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, leading to gasdermin-D (GSDMD) cleavage and subsequent pyroptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5#function" }, { "database": "UniProtKB", "id": "ARBA00024315", "url": "https://www.uniprot.org/uniprotkb/ARBA00024315#function" }, { "database": "UniProtKB", "id": "A0A9J7JPN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPN4#function" }, { "database": "UniProtKB", "id": "A0A9J7JYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYT8#function" } ] }, { "annotation": "Constitutes the precursor of the Nlrp1a inflammasome, which mediates autoproteolytic processing within the FIIND domain to generate the N-terminal and C-terminal parts, which are associated non-covalently in absence of pathogens and other damage-associated signals.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5#function" }, { "database": "UniProtKB", "id": "ARBA00029394", "url": "https://www.uniprot.org/uniprotkb/ARBA00029394#function" }, { "database": "UniProtKB", "id": "A0A9J7JPN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPN4#function" }, { "database": "UniProtKB", "id": "A0A9J7JYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYT8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nlrp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5", "locus": {} } ], "crossref": [ { "id": "cd08320", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08320", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08330", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08330", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756113", "url": "https://www.ncbi.nlm.nih.gov/gene/100756113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756113", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756113", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDG5", "url": "https://www.orthodb.org/?gene=A0A9J7GDG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46985", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46985", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46985:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46985:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPN4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLPWLRTHTEGGHHRRARADMSRTTILAYYLEKLNKEELKEFQHRLLNQVALPEASSTEVASNLVAQYGSRRAWDLALHTWKQMGKKQLCSQAQQEKGLTPSHHTSLSSSPSTSNMESSSRFTSSSDHGYGSSCEQLSEKETFQNKPINSECRMRETIKITSPNQKRESPCHTPSWKTEDFLQNYTQLLLLQRSCPRGHRSMVRERGHQDIKDRGHLIAIQDLFGPSLGSQKEPQLVILEGAAGVGKSTLARQVKRAWEEGQLYRDRFQHVFYFSCRELAQCKQQSLAELIAKYENVHKDLIEEILSQPKKLLFILDGIDEPAWTLQNPKLCQHWSQKWPVQTLLSSLLRKSILPKASLLLTARTTDLQKLIPSLGQPRWVEVLGFSESGRKEYFYTYFADEREAITAFSLVESNPVLLTLCLVPWVSWLVCTCLTQQMGQWGELSLTAQSTTALCLKYLSQILPVRPLGPRLRGLCSLAAEGICKGKSLFSLGDFRKQKLPGSVISTFMNMGVLQKLPNSTRYSFAHLCLQEFFAAMSCVLIYEEEKDKRESFKIVEKLLKVYGRLDLFEAPTMRFLFGLLSDQAMDEMENIFICRLPLERRWELLKRLLKEAHPKHSYSLGLLHCLYEIQHKELLTRAMHNVQGTRVHVQTDMAHPVFQTNMKHLVVQTDAELMVVTFCIKFCFPVKRLQLDCGRQQEQVLRAPRLVLSRWTPITKASWQILFSILEFSGSLEELDLSGNLLSNYAVQSLCRTLRQPGCHLKTLWLVNCGLTSSHCVDLTSVLKASSSLTELDLQLNDLGDSGVRLLCKGLRNPACNLRILLLDQGSLSDKVMAQLKALKAENPRLLIQSTRKPHGMASTSGLDKGKTSAGPSSLKRLRLQSEEDAPRRAQLKLSHTPYSSSLGDKLTESLGTEDGFWGSTGPVATEVVDRERNLYRVQLPMAGSYHWPSTGLRFVVTRAVTVEIEFCAWSQFLGKTPLEQSYMVAGPLFDIKAEQGAVAAVYLPHFVALQGIQEDTLKFQVAHFLNDVVVLEAPAKVEPHCAVLKKPSFSPIGVVLKIISATRRLLPITSITLLYHQPHTEELKFHLYLIPNDCTIRKAVDDEEMKFQFVRIHKPPPIGCLYVGSRYTVSGSETMEITPKELELCYRSSSEAQLFSEIYVGHLQSGIRLEIKDKNADAVVWEALLKPGDLRPASTLVAPATTVARPFLHFVDQHREQLVARVTSVDPILDKLHSQVLSEEQYEMVRAEATNPDKMRKLFSYSRSWDQARKSQLYQALKAIHPHLILELWEVWGKALGEWVS", 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"length": 1304, "header": "tr|A0A9J7JPN4-1|A0A9J7JPN4_CRIGR Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Nlrp1 PE=3 SV=1 CANONICAL=A0A9J7GDG5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5/entry#A0A9J7JYT8-1", "sequence": { "sequence": "MSRTTILAYYLEKLNKEELKEFQHRLLNQVALPEASSTEVASNLVAQYGSRRAWDLALHTWKQMGKKQLCSQAQQEKGLTPSHHTSLSSSPSTSNMESSSRFTSSSDHGYGSSCEQLSEKETFQNKPINSECRMRETIKITSPNQKRESPCHTPSWKTEDFLQNYTQLLLLQRSCPRGHRSMVRERGHQDIKDRGHLIAIQDLFGPSLGSQKEPQLVILEGAAGVGKSTLARQVKRAWEEGQLYRDRFQHVFYFSCRELAQCKQQSLAELIAKYENVHKDLIEEILSQPKKLLFILDGIDEPAWTLQNPKLCQHWSQKWPVQTLLSSLLRKSILPKASLLLTARTTDLQKLIPSLGQPRWVEVLGFSESGRKEYFYTYFADEREAITAFSLVESNPVLLTLCLVPWVSWLVCTCLTQQMGQWGELSLTAQSTTALCLKYLSQILPVRPLGPRLRGLCSLAAEGICKGKSLFSLGDFRKQKLPGSVISTFMNMGVLQKLPNSTRYSFAHLCLQEFFAAMSCVLIYEEEKDKRESFKIVEKLLKVYGRLDLFEAPTMRFLFGLLSDQAMDEMENIFICRLPLERRWELLKRLLKEAHPKHSYSLGLLHCLYEIQHKELLTRAMHNVQGTRVHVQTDMAHPVFQTNMKHLVVQTDAELMVVTFCIKFCFPVKRLQLDCGRQQEQVLRAPRLVLSRWTPITKASWQILFSILEFSGSLEELDLSGNLLSNYAVQSLCRTLRQPGCHLKTLWLVNCGLTSSHCVDLTSVLKASSSLTELDLQLNDLGDSGVRLLCKGLRNPACNLRILLLDQGSLSDKVMAQLKALKAENPRLLIQSTRKPHGMASTSGLDKGKTSAGPSSLKRLRLQSEEDAPRRAQLKLSHTPYSSSLGDKLTESLGTEDGFWGSTGPVATEVVDRERNLYRVQLPMAGSYHWPSTGLRFVVTRAVTVEIEFCAWSQFLGKTPLEQSYMVAGPLFDIKAEQGAVAAVYLPHFVALQGIQEDTLKFQVAHFLNDVVVLEAPAKVEPHCAVLKKPSFSPIGVVLKIISATRRLLPITSITLLYHQPHTEELKFHLYLIPNDCTIRKAVDDEEMKFQFVRIHKPPPIGCLYVGSRYTVSGSETMEITPKELELCYRSSSEAQLFSEIYVGHLQSGIRLEIKDKNADAVVWEALLKPGDLRPASTLVAPATTVARPFLHFVDQHREQLVARVTSVDPILDKLHSQVLSEEQYEMVRAEATNPDKMRKLFSYSRSWDQARKSQLYQALKAIHPHLILELWEVWGKALGEWVS", "length": 1284, "header": "tr|A0A9J7JYT8-1|A0A9J7JYT8_CRIGR Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Nlrp1 PE=3 SV=1 CANONICAL=A0A9J7GDG5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756113", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756113", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5" } ], "pmid": "" }, { "name": "canonical inflammasome complex", "id": "GO:0061702", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061702", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDG5" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": 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"uniprot_canonical_ac": "A0A9J7GDH0-1", "uniprot_ac": "A0A9J7GDH0", "uniprot_id": "A0A9J7GDH0_CRIGR", "mass": { "chemical_mass": 273899.0, "monoisotopic_mass": 273899.0 }, "refseq": { "ac": "XP_027283127", "name": "myosin phosphatase Rho-interacting protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283127" }, "gene_names": [ { "name": "Mprip", "type": "recommended", "evidence": [ { "id": "A0A9J7GDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0" } ] }, { "name": "Mprip", "type": "synonym", "evidence": [ { "id": "XP_027283127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283127" } ] } ], "protein_names": [ { "name": "Myosin phosphatase Rho-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A9J7GDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#names_and_taxonomy" } ] }, { "name": "Rho-interacting protein 3", "type": "synonym", "evidence": [ { "id": "A0A9J7GDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#names_and_taxonomy" } ] }, { "name": "myosin phosphatase Rho-interacting protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027283127", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283127" } ] }, { "name": "p116Rip", "type": "synonym", "evidence": [ { "id": "A0A9J7GDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283127" } ] }, { "annotation": "Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0#function" }, { "database": "UniProtKB", "id": "ARBA00057680", "url": "https://www.uniprot.org/uniprotkb/ARBA00057680#function" }, { "database": "UniProtKB", "id": "A0A9J7KBK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBK6#function" }, { "database": "UniProtKB", "id": "A0A9J7H2M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2M2#function" }, { "database": "UniProtKB", "id": "A0A9J7H394", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H394#function" }, { "database": "UniProtKB", "id": "A0A8C2LD88", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD88#function" }, { "database": "UniProtKB", "id": "A0A8C2LIC7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIC7#function" }, { "database": "UniProtKB", "id": "A0A9J7GIK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIK4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mprip", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0", "locus": {} } ], "crossref": [ { "id": "cd01236", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01236", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13275", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13275", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766510", "url": "https://www.ncbi.nlm.nih.gov/gene/100766510", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766510", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766510", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDH0", "url": "https://www.orthodb.org/?gene=A0A9J7GDH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17271:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17271:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283127", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LD88", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LD88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LIC7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LIC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GIK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GIK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1G9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2M2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H394", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H394", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H394-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H394-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBK6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSGGSSIPSAEKVPTTKSTLWQEEMRAKDQPDGNSLNPAQSPSQTLPPAVCTPREIGLESKEDESAMSGDRVDGGRKVRVESGYFSLEKAKQDLRAEEQLPPPLSPPSPSTPHSRYGCPGSPSQELGHPLHSPGLPAPSRMVYSICPNSLGKASRPPNHMDSSSAGGWGTEILGSTFAFKASRQYAALADVPKAIRISHREAFQVERRRLENRTRARSPGREEVARLFGNERRRSQVIEKFEALDIEKAEHMETNMLIMTTPSSDTRQGRSEKRAIPRKRDFASEAPTAPLSDACPLSPHRRAKSLDRRSTEPSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSMAEEAADLDGEIDLSTCYNVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPASAPDVTSSLPEEKNKSTSSFETCPRPNEKQETEPGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQALAQERANTVGSSEAGEPGRPEAEPGELERERARRREERRKRFGMLDTVDGPGVEDTPLRMDIDRSPGLLGPPDLKTQNVHVEIEQRWHQVETTPLREEKQVPIAPLHLSLEDRSERLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQTEVATSPSGAWQRLHRVNQDLQSELEAQCRRQELITQQIQTLKHSYGEAKDAIRHHEAEIQTLQARLGNAATELALKEQALAKLKGELKLEQGKVREQLEEWQHSKAMLSGQLRASEQKLKSTEALLLEKTQELRDLETQQALQRDRQKEVQKLQECIAELSQQLGSSEQAQNMMEKKLKRNYTLLLESCEQEKQALLQNLKEVEDKASAYEEQLQGHVQQVEALQKEKLSETCKGSEQVHLLEEELQAREASIRQLAQHVQSLHEERDLIKQQFQELMERVATSDGDVAELQEKLRGKEADYQNLEHSHHRVSIQLQSVRTLLREKEEELKHIKEAHERVLEKKDQDLNEALVKMIALGSSLEETEIKLQEKEECLRRFVSDSPKDAKEPQSTAEQMEDSGILPLGSVTRVFPGFAHSQPEDEDPGAGQGEECSSGSPSREDMVAPKSADVPDREGNLQSSSKSDQGAPLKRPRIRFSTIQCQRYIHPEGCAKAWTSSTSSDTSQDQSPSEDSVSSEATPSTLPAAADAETYISIIHSLETKLYVTEEKLKDVTVRLESQQGQSQEALLALHQQWAGTEAQLREQLRASLLQASALASQLEQERQEKATNIEHHPEELGDFQVKNSQALACLENCWRKLRSLPFADQEEGQDACAASLANIESMLVGAIKALQPWASPIDSSAQTQQEKGHPMESGLATPVQQPCQPILNEQEHRKLLSAQIVLEASLINQIADSLKNTTSDVYGVLCELTQSGEWPLKEESAALSAGAPVEIWAKKVLVNGEFWSQVESLSKHLGTLGQETACTSGDRQQHIPQSLADATWIRAELSYATQSLRELFHHRLQSIQETLQGTQAALQQHKCMLGEILGAYQTPDFERVIQQILETLRNPAGREDQVQTSWDQSPLGEVLKPDTEGSQEPLQAFHQSPEVLAAIQDELAQQLREKASILEEISAALPALPPTEQLGGCQRLLQMSQHLSYDACLEGLGQYSSLLVQDAIIQAQVCYAACRIRLEYEKELRFYKKACQEATGDSCQKRAQAVGVLKEEYEELLHKQKSEYQKVITLIEKENTELKAKVSQMDHQQRCLQEAESKHSESMFALQGRYEEEIRCMVEQLSHTESTLQAERSRVLSQLDASVKDRQAMEQQHVQQMKMLEDRFQLKVRELQAVHQEELRALQEHYIWSLRGALSLCQPSHPDSPLAPRPSEPRAVPTAKDEAESMTGLRERIQELEAQMDVMREELGHKELEGDVATLREKYQRDFESLKATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSLKEGLTVQERLKLFESRDLKKD", "length": 2420, "header": "tr|A0A9J7GDH0-1|A0A9J7GDH0_CRIGR Isoform 1 of Myosin phosphatase Rho-interacting protein OS=Cricetulus griseus OX=10029 GN=Mprip PE=4 SV=1 CANONICAL=A0A9J7GDH0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LD88-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#A0A8C2LD88-1", "sequence": { "sequence": "MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSGGSSIPSAEKVPTTKSTLWQEEMRAKDQPDGNSLNPAQSPSQTLPPAVCTPREIGLESKEDESAMSGDRVDGGRKVRVESGYFSLEKAKQDLRAEEQLPPPLSPPSPSTPHSRRSQVIEKFEALDIEKAEHMETNMLIMTTPSSDTRQGRSEKRAIPRKRDFASEAPTAPLSDACPLSPHRRAKSLDRRSTEPSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSMAEEAADLDGEIDLSTCYNVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPASAPDVTSSLPEEKNKSTSSFETCPRPNEKQETEPGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQALAQERANTVGSSEAGEPGRPEAEPGELERERARRREERRKRFGMLDTVDGPGVEDTPLRMDIDRSPGLLGPPDLKTQNVHVEIEQRWHQVETTPLREEKQVPIAPLHLSLEDRSERLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSVIEQVSWDN", "length": 1023, "header": "tr|A0A8C2LD88-1|A0A8C2LD88_CRIGR Computationally mapped isoform of Myosin phosphatase Rho-interacting protein OS=Cricetulus griseus OX=10029 GN=Mprip PE=4 SV=1 CANONICAL=A0A9J7GDH0-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LIC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#A0A8C2LIC7-1", "sequence": { "sequence": "MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSGGSSIPSAEKVPTTKSTLWQEEMRAKDQPDGNSLNPAQSPSQTLPPAVCTPREIGLESKEDESAMSGDRVDGGRKVRVESGYFSLEKAKQDLRAEEQLPPPLSPPSPSTPHSRRSQVIEKFEALDIEKAEHMETNMLIMTTPSSDTRQGRSEKRAIPRKRDFASEAPTAPLSDACPLSPHRRAKSLDRRSTEPSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSMAEEAADLDGEIDLSTCYNVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPASAPDVTSSLPEEKNKSTSSFETCPRPNEKQETEPGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQALAQERANTVGSSEAGEPGRPEAEPGELERERARRREERRKRFGMLDTVDGPGVEDTPLRMDIDRSPGLLGPPDLKTQNVHVEIEQRWHQVETTPLREEKQVPIAPLHLSLEDRSERLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSLKEGLTVQERLKLFESRDLKKD", "length": 1036, "header": "tr|A0A8C2LIC7-1|A0A8C2LIC7_CRIGR Computationally mapped isoform of Myosin phosphatase Rho-interacting protein OS=Cricetulus griseus OX=10029 GN=Mprip PE=4 SV=1 CANONICAL=A0A9J7GDH0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#A0A9J7GDH0-1", "sequence": { "sequence": "MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSGGSSIPSAEKVPTTKSTLWQEEMRAKDQPDGNSLNPAQSPSQTLPPAVCTPREIGLESKEDESAMSGDRVDGGRKVRVESGYFSLEKAKQDLRAEEQLPPPLSPPSPSTPHSRYGCPGSPSQELGHPLHSPGLPAPSRMVYSICPNSLGKASRPPNHMDSSSAGGWGTEILGSTFAFKASRQYAALADVPKAIRISHREAFQVERRRLENRTRARSPGREEVARLFGNERRRSQVIEKFEALDIEKAEHMETNMLIMTTPSSDTRQGRSEKRAIPRKRDFASEAPTAPLSDACPLSPHRRAKSLDRRSTEPSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSMAEEAADLDGEIDLSTCYNVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPASAPDVTSSLPEEKNKSTSSFETCPRPNEKQETEPGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQALAQERANTVGSSEAGEPGRPEAEPGELERERARRREERRKRFGMLDTVDGPGVEDTPLRMDIDRSPGLLGPPDLKTQNVHVEIEQRWHQVETTPLREEKQVPIAPLHLSLEDRSERLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQTEVATSPSGAWQRLHRVNQDLQSELEAQCRRQELITQQIQTLKHSYGEAKDAIRHHEAEIQTLQARLGNAATELALKEQALAKLKGELKLEQGKVREQLEEWQHSKAMLSGQLRASEQKLKSTEALLLEKTQELRDLETQQALQRDRQKEVQKLQECIAELSQQLGSSEQAQNMMEKKLKRNYTLLLESCEQEKQALLQNLKEVEDKASAYEEQLQGHVQQVEALQKEKLSETCKGSEQVHLLEEELQAREASIRQLAQHVQSLHEERDLIKQQFQELMERVATSDGDVAELQEKLRGKEADYQNLEHSHHRVSIQLQSVRTLLREKEEELKHIKEAHERVLEKKDQDLNEALVKMIALGSSLEETEIKLQEKEECLRRFVSDSPKDAKEPQSTAEQMEDSGILPLGSVTRVFPGFAHSQPEDEDPGAGQGEECSSGSPSREDMVAPKSADVPDREGNLQSSSKSDQGAPLKRPRIRFSTIQCQRYIHPEGCAKAWTSSTSSDTSQDQSPSEDSVSSEATPSTLPAAADAETYISIIHSLETKLYVTEEKLKDVTVRLESQQGQSQEALLALHQQWAGTEAQLREQLRASLLQASALASQLEQERQEKATNIEHHPEELGDFQVKNSQALACLENCWRKLRSLPFADQEEGQDACAASLANIESMLVGAIKALQPWASPIDSSAQTQQEKGHPMESGLATPVQQPCQPILNEQEHRKLLSAQIVLEASLINQIADSLKNTTSDVYGVLCELTQSGEWPLKEESAALSAGAPVEIWAKKVLVNGEFWSQVESLSKHLGTLGQETACTSGDRQQHIPQSLADATWIRAELSYATQSLRELFHHRLQSIQETLQGTQAALQQHKCMLGEILGAYQTPDFERVIQQILETLRNPAGREDQVQTSWDQSPLGEVLKPDTEGSQEPLQAFHQSPEVLAAIQDELAQQLREKASILEEISAALPALPPTEQLGGCQRLLQMSQHLSYDACLEGLGQYSSLLVQDAIIQAQVCYAACRIRLEYEKELRFYKKACQEATGDSCQKRAQAVGVLKEEYEELLHKQKSEYQKVITLIEKENTELKAKVSQMDHQQRCLQEAESKHSESMFALQGRYEEEIRCMVEQLSHTESTLQAERSRVLSQLDASVKDRQAMEQQHVQQMKMLEDRFQLKVRELQAVHQEELRALQEHYIWSLRGALSLCQPSHPDSPLAPRPSEPRAVPTAKDEAESMTGLRERIQELEAQMDVMREELGHKELEGDVATLREKYQRDFESLKATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSLKEGLTVQERLKLFESRDLKKD", "length": 2420, "header": "tr|A0A9J7GDH0-1|A0A9J7GDH0_CRIGR Isoform 1 of Myosin phosphatase Rho-interacting protein OS=Cricetulus griseus OX=10029 GN=Mprip PE=4 SV=1 CANONICAL=A0A9J7GDH0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GIK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#A0A9J7GIK4-1", "sequence": { "sequence": "MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSGGSSIPSAEKVPTTKSTLWQEEMRAKDQPDGNSLNPAQSPSQTLPPAVCTPREIGLESKEDESAMSGDRVDGGRKVRVESGYFSLEKAKQDLRAEEQLPPPLSPPSPSTPHSRRSQVIEKFEALDIEKAEHMETNMLIMTTPSSDTRQGRSEKRAIPRKRDFASEAPTAPLSDACPLSPHRRAKSLDRRSTEPSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSMAEEAADLDGEIDLSTCYNVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPASAPDVTSSLPEEKNKSTSSFETCPRPNEKQETEPGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQALAQERANTVGSSEAGEPGRPEAEPGELERERARRREERRKRFGMLDTVDGPGVEDTPLRMDIDRSPGLLGPPDLKTQNVHVEIEQRWHQVETTPLREEKQVPIAPLHLSLEDRSERLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQTEVATSPSGAWQRLHRVNQDLQSELEAQCRRQELITQQIQTLKHSYGEAKDAIRHHEAEIQTLQARLGNAATELALKEQALAKLKGELKLEQGKVREQLEEWQHSKAMLSGQLRASEQKLKSTEALLLEKTQELRDLETQQALQRDRQKEVQKLQECIAELSQQLGSSEQAQNMMEKKLKRNYTLLLESCEQEKQALLQNLKEVEDKASAYEEQLQGHVQQVEALQKEKLSETCKGSEQVHLLEEELQAREASIRQLAQHVQSLHEERDLIKQQFQELMERVATSDGDVAELQEKLRGKEADYQNLEHSHHRVSIQLQSVRTLLREKEEELKHIKEAHERVLEKKDQDLNEALVKMIALGSSLEETEIKLQEKEECLRRFVSDSPKDAKEPQSTAEQMEDSGILPLGSVTRVFPGFAHSQPEDEDPGAGQGEECSSGSPSREDMVAPKSADVPDREGNLQSSSKSDQGAPLKRPRIRFSTIQCQRYIHPEGCAKAWTSSTSSDTSQDQSPSEDSVSSEATPSTLPAAADAETYISIIHSLETKLYVTEEKLKDVTVRLESQQGQSQEALLALHQQWAGTEAQLREQLRASLLQASALASQLEQERQEKATNIEHHPEELGDFQVKNSQALACLENCWRKLRSLPFADQEEGQDACAASLANIESMLVGAIKALQPWASPIDSSAQTQQEKGHPMESGLATPVQQPCQPILNEQEHRKLLSAQIVLEASLINQIADSLKNTTSDVYGVLCELTQSGEWPLKEESAALSAGAPVEIWAKKVLVNGEFWSQVESLSKHLGTLGQETACTSGDRQQHIPQSLADATWIRAELSYATQSLRELFHHRLQSIQETLQGTQAALQQHKCMLGEILGAYQTPDFERVIQQILETLRNPAGREDQVQTSWDQSPLGEVLKPDTEGSQEPLQAFHQSPEVLAAIQDELAQQLREKASILEEISAALPALPPTEQLGGCQRLLQMSQHLSYDACLEGLGQYSSLLVQDAIIQAQVCYAACRIRLEYEKELRFYKKACQEATGDSCQKRAQAVGVLKEEYEELLHKQKSEYQKVITLIEKENTELKAKVSQMDHQQRCLQEAESKHSESMFALQGRYEEEIRCMVEQLSHTESTLQAERSRVLSQLDASVKDRQAMEQQHVQQMKMLEDRFQLKVRELQAVHQEELRALQEHYIWSLRGALSLCQPSHPDSPLAPRPSEPRAVPTAKDEAESMTGLRERIQELEAQMDVMREELGHKELEGDVATLREKYQRDFESLKATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSLKEGLTVQERLKLFESRDLKKD", "length": 2302, "header": "tr|A0A9J7GIK4-1|A0A9J7GIK4_CRIGR Computationally mapped isoform of Myosin phosphatase Rho-interacting protein OS=Cricetulus griseus OX=10029 GN=Mprip PE=4 SV=1 CANONICAL=A0A9J7GDH0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#A0A9J7H1G9-1", "sequence": { "sequence": "METNMLIMTTPSSDTRQGRSEKRAIPRKRDFASEAPTAPLSDACPLSPHRRAKSLDRRSTEPSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSMAEEAADLDGEIDLSTCYNVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPASAPDVTSSLPEEKNKSTSSFETCPRPNEKQETEPGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQALAQERANTVGSSEAGEPGRPEAEPGELERERARRREERRKRFGMLDTVDGPGVEDTPLRMDIDRSPGLLGPPDLKTQNVHVEIEQRWHQVETTPLREEKQVPIAPLHLSLEDRSERLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQTEVATSPSGAWQRLHRVNQDLQSELEAQCRRQELITQQIQTLKHSYGEAKDAIRHHEAEIQTLQARLGNAATELALKEQALAKLKGELKLEQGKVREQLEEWQHSKAMLSGQLRASEQKLKSTEALLLEKTQELRDLETQQALQRDRQKEVQKLQECIAELSQQLGSSEQAQNMMEKKLKRNYTLLLESCEQEKQALLQNLKEVEDKASAYEEQLQGHVQQVEALQKEKLSETCKGSEQVHLLEEELQAREASIRQLAQHVQSLHEERDLIKQQFQELMERVATSDGDVAELQEKLRGKEADYQNLEHSHHRVSIQLQSVRTLLREKEEELKHIKEAHERVLEKKDQDLNEALVKMIALGSSLEETEIKLQEKEECLRRFVSDSPKDAKEPQSTAEQMEDSGILPLGSVTRVFPGFAHSQPEDEDPGAGQGEECSSGSPSREDMVAPKSADVPDREGNLQSSSKSDQGAPLKRPRIRFSTIQCQRYIHPEGCAKAWTSSTSSDTSQDQSPSEDSVSSEATPSTLPAAADAETYISIIHSLETKLYVTEEKLKDVTVRLESQQGQSQEALLALHQQWAGTEAQLREQLRASLLQASALASQLEQERQEKATNIEHHPEELGDFQVKNSQALACLENCWRKLRSLPFADQEEGQDACAASLANIESMLVGAIKALQPWASPIDSSAQTQQEKGHPMESGLATPVQQPCQPILNEQEHRKLLSAQIVLEASLINQIADSLKNTTSDVYGVLCELTQSGEWPLKEESAALSAGAPVEIWAKKVLVNGEFWSQVESLSKHLGTLGQETACTSGDRQQHIPQSLADATWIRAELSYATQSLRELFHHRLQSIQETLQGTQAALQQHKCMLGEILGAYQTPDFERVIQQILETLRNPAGREDQVQTSWDQSPLGEVLKPDTEGSQEPLQAFHQSPEVLAAIQDELAQQLREKASILEEISAALPALPPTEQLGGCQRLLQMSQHLSYDACLEGLGQYSSLLVQDAIIQAQVCYAACRIRLEYEKELRFYKKACQEATGDSCQKRAQAVGVLKEEYEELLHKQKSEYQKVITLIEKENTELKAKVSQMDHQQRCLQEAESKHSESMFALQGRYEEEIRCMVEQLSHTESTLQAERSRVLSQLDASVKDRQAMEQQHVQQMKMLEDRFQLKVRELQAVHQEELRALQEHYIWSLRGALSLCQPSHPDSPLAPRPSEPRAVPTAKDEAESMTGLRERIQELEAQMDVMREELGHKELEGDVATLREKYQRDFESLKATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSLKEGLTVQERLKLFESRDLKKD", "length": 1987, "header": "tr|A0A9J7H1G9-1|A0A9J7H1G9_CRIGR Computationally mapped isoform of Myosin phosphatase Rho-interacting protein isoform X7 OS=Cricetulus griseus OX=10029 GN=Mprip PE=4 SV=1 CANONICAL=A0A9J7GDH0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#A0A9J7H2M2-1", "sequence": { "sequence": "MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSGGSSIPSAEKVPTTKSTLWQEEMRAKDQPDGNSLNPAQSPSQTLPPAVCTPREIGLESKEGLPAPSRMVYSICPNSLGKASRPPNHMDSSSAGGWGTEILGSTFAFKASRQYAALADVPKAIRISHREAFQVERRRLENRTRARSPGREEVARLFGNERRRSQVIEKFEALDIEKAEHMETNMLIMTTPSSDTRQGRSEKRAIPRKRPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSMAEEAADLDGEIDLSTCYNVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPASAPDVTSSLPEEKNKSTSSFETCPRPNEKQETEPGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQALAQERANTVGSSEAGEPGRPEAEPGELERERARRREERRKRFGMLDTVDGPGVEDTPLRMDIDRSPGLLGPPDLKTQNVHVEIEQRWHQVETTPLREEKQVPIAPLHLSLEDRSERLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQTEVATSPSGAWQRLHRVNQDLQSELEAQCRRQELITQQIQTLKHSYGEAKDAIRHHEAEIQTLQARLGNAATELALKEQALAKLKGELKLEQGKVREQLEEWQHSKAMLSGQLRASEQKLKSTEALLLEKTQELRDLETQQALQRDRQKEVQKLQECIAELSQQLGSSEQAQNMMEKKLKRNYTLLLESCEQEKQALLQNLKEVEDKASAYEEQLQGHVQQVEALQKEKLSETCKGSEQVHLLEEELQAREASIRQLAQHVQSLHEERDLIKQQFQELMERVATSDGDVAELQEKLRGKEADYQNLEHSHHRVSIQLQSVRTLLREKEEELKHIKEAHERVLEKKDQDLNEALVKMIALGSSLEETEIKLQEKEECLRRFVSDSPKDAKEPQSTAEQMEDSGILPLGSVTRVFPGFAHSQPEDEDPGAGQGEECSSGSPSREDMVAPKSADVPDREGNLQSSSKSDQGAPLKRPRIRFSTIQCQRYIHPEGCAKAWTSSTSSDTSQDQSPSEDSVSSEATPSTLPAAADAETYISIIHSLETKLYVTEEKLKDVTVRLESQQGQSQEALLALHQQWAGTEAQLREQLRASLLQASALASQLEQERQEKATNIEHHPEELGDFQVKNSQALACLENCWRKLRSLPFADQEEGQDACAASLANIESMLVGAIKALQPWASPIDSSAQTQQEKGHPMESGLATPVQQPCQPILNEQEHRKLLSAQIVLEASLINQIADSLKNTTSDVYGVLCELTQSGEWPLKEESAALSAGAPVEIWAKKVLVNGEFWSQVESLSKHLGTLGQETACTSGDRQQHIPQSLADATWIRAELSYATQSLRELFHHRLQSIQETLQGTQAALQQHKCMLGEILGAYQTPDFERVIQQILETLRNPAGREDQVQTSWDQSPLGEVLKPDTEGSQEPLQAFHQSPEVLAAIQDELAQQLREKASILEEISAALPALPPTEQLGGCQRLLQMSQHLSYDACLEGLGQYSSLLVQDAIIQAQVCYAACRIRLEYEKELRFYKKACQEATGDSCQKRAQAVGVLKEEYEELLHKQKSEYQKVITLIEKENTELKAKVSQMDHQQRCLQEAESKHSESMFALQGRYEEEIRCMVEQLSHTESTLQAERSRVLSQLDASVKDRQAMEQQHVQQMKMLEDRFQLKVRELQAVHQEELRALQEHYIWSLRGALSLCQPSHPDSPLAPRPSEPRAVPTAKDEAESMTGLRERIQELEAQMDVMREELGHKELEGDVATLREKYQRDFESLKATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSLKEGLTVQERLKLFESRDLKKD", "length": 2313, "header": "tr|A0A9J7H2M2-1|A0A9J7H2M2_CRIGR Computationally mapped isoform of Myosin phosphatase Rho-interacting protein OS=Cricetulus griseus OX=10029 GN=Mprip PE=4 SV=1 CANONICAL=A0A9J7GDH0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H394-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#A0A9J7H394-1", "sequence": { "sequence": "MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSGGSSIPSAEKVPTTKSTLWQEEMRAKDQPDGNSLNPAQSPSQTLPPAVCTPREIGLESKEGLPAPSRMVYSICPNSLGKASRPPNHMDSSSAGGWGTEILGSTFAFKASRQYAALADVPKAIRISHREAFQVERRRLENRTRARSPGREEVARLFGNERRRSQVIEKFEALDIEKAEHMETNMLIMTTPSSDTRQGRSEKRAIPRKRDFASEAPTAPLSDACPLSPHRRAKSLDRRSTEPSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSMAEEAADLDGEIDLSTCYNVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPASAPDVTSSLPEEKNKSTSSFETCPRPNEKQETEPGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQALAQERANTVGSSEAGEPGRPEAEPGELERERARRREERRKRFGMLDTVDGPGVEDTPLRMDIDRSPGLLGPPDLKTQNVHVEIEQRWHQVETTPLREEKQVPIAPLHLSLEDRSERLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQTEVATSPSGAWQRLHRVNQDLQSELEAQCRRQELITQQIQTLKHSYGEAKDAIRHHEAEIQTLQARLGNAATELALKEQALAKLKGELKLEQGKVREQLEEWQHSKAMLSGQLRASEQKLKSTEALLLEKTQELRDLETQQALQRDRQKEVQKLQECIAELSQQLGSSEQAQNMMEKKLKRNYTLLLESCEQEKQALLQNLKEVEDKASAYEEQLQGHVQQVEALQKEKLSETCKGSEQVHLLEEELQAREASIRQLAQHVQSLHEERDLIKQQFQELMERVATSDGDVAELQEKLRGKEADYQNLEHSHHRVSIQLQSVRTLLREKEEELKHIKEAHERVLEKKDQDLNEALVKMIALGSSLEETEIKLQEKEECLRRFVSDSPKDAKEPQSTAEQMEDSGILPLGSVTRVFPGFAHSQPEDEDPGAGQGEECSSGSPSREDMVAPKSADVPDREGNLQSSSKSDQGAPLKRPRIRFSTIQCQRYIHPEGCAKAWTSSTSSDTSQDQSPSEDSVSSEATPSTLPAAADAETYISIIHSLETKLYVTEEKLKDVTVRLESQQGQSQEALLALHQQWAGTEAQLREQLRASLLQASALASQLEQERQEKATNIEHHPEELGDFQVKNSQALACLENCWRKLRSLPFADQEEGQDACAASLANIESMLVGAIKALQPWASPIDSSAQTQQEKGHPMESGLATPVQQPCQPILNEQEHRKLLSAQIVLEASLINQIADSLKNTTSDVYGVLCELTQSGEWPLKEESAALSAGAPVEIWAKKVLVNGEFWSQVESLSKHLGTLGQETACTSGDRQQHIPQSLADATWIRAELSYATQSLRELFHHRLQSIQETLQGTQAALQQHKCMLGEILGAYQTPDFERVIQQILETLRNPAGREDQVQTSWDQSPLGEVLKPDTEGSQEPLQAFHQSPEVLAAIQDELAQQLREKASILEEISAALPALPPTEQLGGCQRLLQMSQHLSYDACLEGLGQYSSLLVQDAIIQAQVCYAACRIRLEYEKELRFYKKACQEATGDSCQKRAQAVGVLKEEYEELLHKQKSEYQKVITLIEKENTELKAKVSQMDHQQRCLQEAESKHSESMFALQGRYEEEIRCMVEQLSHTESTLQAERSRVLSQLDASVKDRQAMEQQHVQQMKMLEDRFQLKVRELQAVHQEELRALQEHYIWSLRGALSLCQPSHPDSPLAPRPSEPRAVPTAKDEAESMTGLRERIQELEAQMDVMREELGHKELEGDVATLREKYQRDFESLKATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSVIEQVSWDN", "length": 2336, "header": "tr|A0A9J7H394-1|A0A9J7H394_CRIGR Computationally mapped isoform of Myosin phosphatase Rho-interacting protein OS=Cricetulus griseus OX=10029 GN=Mprip PE=4 SV=1 CANONICAL=A0A9J7GDH0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0/entry#A0A9J7KBK6-1", "sequence": { "sequence": "MSAAKENPCRKFQANIFNKSKCQNCFKPRESHLLNDEDLTQAKPIYGGWLLLAPDGTDFDNPVHRSRKWQRRFFILYEHGLLRYALDEMPTTLPQGTINMNQCTDVVDGEARTGQKFSLCILTPDKEHFIRAETKEIISGWLEMLMVYPRTNKQNQKKKRKVEPPTPQEPGPAKMAVTSSSGGSGGSSIPSAEKVPTTKSTLWQEEMRAKDQPDGNSLNPAQSPSQTLPPAVCTPREIGLESKEGLPAPSRMVYSICPNSLGKASRPPNHMDSSSAGGWGTEILGSTFAFKASRQYAALADVPKAIRISHREAFQVERRRLENRTRARSPGREEVARLFGNERRRSQVIEKFEALDIEKAEHMETNMLIMTTPSSDTRQGRSEKRAIPRKRDFASEAPTAPLSDACPLSPHRRAKSLDRRSTEPSMTPDLLNFKKGWLTKQYEDGQWKKHWFVLADQSLRYYRDSMAEEAADLDGEIDLSTCYNVTEYPVQRNYGFQIHTKEGEFTLSAMTSGIRRNWIQTIMKHVLPASAPDVTSSLPEEKNKSTSSFETCPRPNEKQETEPGEPDPEQKKSRARERRREGRSKTFDWAEFRPIQQALAQERANTVGSSEAGEPGRPEAEPGELERERARRREERRKRFGMLDTVDGPGVEDTPLRMDIDRSPGLLGPPDLKTQNVHVEIEQRWHQVETTPLREEKQVPIAPLHLSLEDRSERLSTHELTSLLEKELEQSQKEASDLLEQNRLLQDQLRVALGREQSAREGYVLQTEVATSPSGAWQRLHRVNQDLQSELEAQCRRQELITQQIQTLKHSYGEAKDAIRHHEAEIQTLQARLGNAATELALKEQALAKLKGELKLEQGKVREQLEEWQHSKAMLSGQLRASEQKLKSTEALLLEKTQELRDLETQQALQRDRQKEVQKLQECIAELSQQLGSSEQAQNMMEKKLKRNYTLLLESCEQEKQALLQNLKEVEDKASAYEEQLQGHVQQVEALQKEKLSETCKGSEQVHLLEEELQAREASIRQLAQHVQSLHEERDLIKQQFQELMERVATSDGDVAELQEKLRGKEADYQNLEHSHHRVSIQLQSVRTLLREKEEELKHIKEAHERVLEKKDQDLNEALVKMIALGSSLEETEIKLQEKEECLRRFVSDSPKDAKEPQSTAEQMEDSGILPLGSVTRVFPGFAHSQPEDEDPGAGQGEECSSGSPSREDMVAPKSADVPDREGNLQSSSKSDQGAPLKRPRIRFSTIQCQRYIHPEGCAKAWTSSTSSDTSQDQSPSEDSVSSEATPSTLPAAADAETYISIIHSLETKLYVTEEKLKDVTVRLESQQGQSQEALLALHQQWAGTEAQLREQLRASLLQASALASQLEQERQEKATNIEHHPEELGDFQVKNSQALACLENCWRKLRSLPFADQEEGQDACAASLANIESMLVGAIKALQPWASPIDSSAQTQQEKGHPMESGLATPVQQPCQPILNEQEHRKLLSAQIVLEASLINQIADSLKNTTSDVYGVLCELTQSGEWPLKEESAALSAGAPVEIWAKKVLVNGEFWSQVESLSKHLGTLGQETACTSGDRQQHIPQSLADATWIRAELSYATQSLRELFHHRLQSIQETLQGTQAALQQHKCMLGEILGAYQTPDFERVIQQILETLRNPAGREDQVQTSWDQSPLGEVLKPDTEGSQEPLQAFHQSPEVLAAIQDELAQQLREKASILEEISAALPALPPTEQLGGCQRLLQMSQHLSYDACLEGLGQYSSLLVQDAIIQAQVCYAACRIRLEYEKELRFYKKACQEATGDSCQKRAQAVGVLKEEYEELLHKQKSEYQKVITLIEKENTELKAKVSQMDHQQRCLQEAESKHSESMFALQGRYEEEIRCMVEQLSHTESTLQAERSRVLSQLDASVKDRQAMEQQHVQQMKMLEDRFQLKVRELQAVHQEELRALQEHYIWSLRGALSLCQPSHPDSPLAPRPSEPRAVPTAKDEAESMTGLRERIQELEAQMDVMREELGHKELEGDVATLREKYQRDFESLKATCERGFAAMEETHQKKIEDLQRQHQRELEKLREEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSINSDIEALRRQYLEELQSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEITRLRTLLTGDGGGESTGLPLTQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRDKKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEKSPEGTTVSGYDIMKSKSNPDFLKKDRSCVTRQLRNIRSKSLKEGLTVQERLKLFESRDLKKD", "length": 2349, "header": "tr|A0A9J7KBK6-1|A0A9J7KBK6_CRIGR Computationally mapped isoform of Myosin phosphatase Rho-interacting protein OS=Cricetulus griseus OX=10029 GN=Mprip PE=4 SV=1 CANONICAL=A0A9J7GDH0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1357, "start_aa": "Thr", "end_pos": 1357, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1357", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 470, "start_aa": "Thr", "end_pos": 470, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr470", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766510", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766510", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDH0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1019, "end_pos": 1021, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1576, "end_pos": 1578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GDH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDH0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 150, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 470, 1357 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1019, "end_pos": 1021 }, { "start_pos": 1576, "end_pos": 1578 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 394, "end_pos": 396 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 614, "end_pos": 616 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDI9-1", "uniprot_ac": "A0A9J7GDI9", "uniprot_id": "A0A9J7GDI9_CRIGR", "mass": { "chemical_mass": 14859.0, "monoisotopic_mass": 14859.0 }, "refseq": { "ac": "XP_027283168", "name": "histone H2B type 3-B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283168" }, "gene_names": [ { "name": "LOC113836811", "type": "recommended", "evidence": [ { "id": "A0A9J7GDI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9" } ] }, { "name": "LOC113836811", "type": "synonym", "evidence": [ { "id": "XP_027283168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283168" } ] } ], "protein_names": [ { "name": "Histone H2B", "type": "recommended", "evidence": [ { "id": "A0A9J7GDI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9/entry#names_and_taxonomy" } ] }, { "name": "histone H2B type 3-B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027283168", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283168" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027283168.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283168" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113836811", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9", "locus": {} } ], "crossref": [ { "id": "A0A9J7GDI9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GDI9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22910", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22910", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113836811", "url": "https://www.ncbi.nlm.nih.gov/gene/113836811", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000558", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000558", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007125", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007125", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113836811", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836811", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDI9", "url": "https://www.orthodb.org/?gene=A0A9J7GDI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H5X9", "url": "https://www.orthodb.org/?gene=A0A9J7H5X9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00125", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283168", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283168", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GDI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5X9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5X9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPDPSKSAPAPKKGSKKAVTKAQKKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSNFLRQSFSV", "length": 134, "header": "tr|A0A9J7GDI9-1|A0A9J7GDI9_CRIGR Isoform 1 of Histone H2B OS=Cricetulus griseus OX=10029 GN=LOC113836811 PE=3 SV=1 CANONICAL=A0A9J7GDI9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GDI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9/entry#A0A9J7GDI9-1", "sequence": { "sequence": "MPDPSKSAPAPKKGSKKAVTKAQKKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSNFLRQSFSV", "length": 134, "header": "tr|A0A9J7GDI9-1|A0A9J7GDI9_CRIGR Isoform 1 of Histone H2B OS=Cricetulus griseus OX=10029 GN=LOC113836811 PE=3 SV=1 CANONICAL=A0A9J7GDI9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9/entry#A0A9J7H5X9-1", "sequence": { "sequence": "MPDPSKSAPAPKKGSKKAVTKAQKKDGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSKRRQRR", "length": 131, "header": "tr|A0A9J7H5X9-1|A0A9J7H5X9_CRIGR Computationally mapped isoform of Histone H2B OS=Cricetulus griseus OX=10029 GN=LOC113836811 PE=3 SV=1 CANONICAL=A0A9J7GDI9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113836811", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836811", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9" } ], "pmid": "" }, { "name": "protein heterodimerization activity", "id": "GO:0046982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9" } ], "pmid": "" }, { "name": "structural constituent of chromatin", "id": "GO:0030527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030527", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9" } ], "pmid": "" }, { "name": "nucleosome", "id": "GO:0000786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000786", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GDI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDI9" }, { "id": "PF00125", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00125" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Core Histone H2A/H2B/H3", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 101, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDJ0-1", "uniprot_ac": "A0A9J7GDJ0", "uniprot_id": "A0A9J7GDJ0_CRIGR", "mass": { "chemical_mass": 37145.0, "monoisotopic_mass": 37145.0 }, "refseq": { "ac": "XP_027279416", "name": "LOW QUALITY PROTEIN: olfactory receptor 50-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279416" }, "gene_names": [ { "name": "LOC100770832", "type": "recommended", "evidence": [ { "id": "A0A9J7GDJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0" } ] }, { "name": "LOC100770832", "type": "synonym", "evidence": [ { "id": "XP_027279416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279416" } ] } ], "protein_names": [ { "name": "Olfactory receptor", "type": "recommended", "evidence": [ { "id": "A0A9J7GDJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: olfactory receptor 50-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027279416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279416" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279416" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100770832", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0", "locus": {} } ], "crossref": [ { "id": "100770832", "url": "https://www.ncbi.nlm.nih.gov/gene/100770832", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770832", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770832", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDJ0", "url": "https://www.orthodb.org/?gene=A0A9J7GDJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48001", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48001", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279416", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFFLLTFPFLSHFQQKTRSTNNQSSVFEFILPGLPKQPEDQDMYSALFLLMYVTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTASKILMNMLTHGQSISYTGCISXMYFFLMFGAIDNFLLTSMAYDRYVAICHPLHYTRIMSQSVCIILVIASWFLSFAGALVHTVLLARLSFFRGNTLHHFFCDLSALIKLSSSDTSINELVILIVGSLVVTVLFICILVSYGHIGATILRTPSIKGICKALCTCGSHLSVVSLYYGTIIGLYFVPSSNKTNDKDVIVSVLYTMVTPMLNPFIYSLRNWDMKGALRNILLRRMYSQ", "length": 329, "header": "tr|A0A9J7GDJ0-1|A0A9J7GDJ0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100770832 PE=3 SV=1 CANONICAL=A0A9J7GDJ0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GDJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0/entry#A0A9J7GDJ0-1", "sequence": { "sequence": "MFFLLTFPFLSHFQQKTRSTNNQSSVFEFILPGLPKQPEDQDMYSALFLLMYVTTVLGNLLIILLIRLDSHLHTPMYFFLSHLAFTDISFSSVTASKILMNMLTHGQSISYTGCISXMYFFLMFGAIDNFLLTSMAYDRYVAICHPLHYTRIMSQSVCIILVIASWFLSFAGALVHTVLLARLSFFRGNTLHHFFCDLSALIKLSSSDTSINELVILIVGSLVVTVLFICILVSYGHIGATILRTPSIKGICKALCTCGSHLSVVSLYYGTIIGLYFVPSSNKTNDKDVIVSVLYTMVTPMLNPFIYSLRNWDMKGALRNILLRRMYSQ", "length": 329, "header": "tr|A0A9J7GDJ0-1|A0A9J7GDJ0_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100770832 PE=3 SV=1 CANONICAL=A0A9J7GDJ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770832", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770832", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GDJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 58, "end_pos": 307, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 }, { "start_pos": 282, "end_pos": 284 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 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"table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDJ4-1", "uniprot_ac": "A0A9J7GDJ4", "uniprot_id": "A0A9J7GDJ4_CRIGR", "mass": { "chemical_mass": 169370.0, "monoisotopic_mass": 169370.0 }, "refseq": { "ac": "XP_003501429", "name": "canalicular multispecific organic anion transporter 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501429" }, "gene_names": [ { "name": "Abcc3", "type": "recommended", "evidence": [ { "id": "A0A9J7GDJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4" } ] }, { "name": "Abcc3", "type": "synonym", "evidence": [ { "id": "XP_003501429", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501429" } ] } ], "protein_names": [ { "name": "Canalicular multispecific organic anion transporter 2", "type": "synonym", "evidence": [ { "id": "A0A9J7GDJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4/entry#names_and_taxonomy" } ] }, { "name": "canalicular multispecific organic anion transporter 2", "type": "synonym", "evidence": [ { "id": "XP_003501429", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501429" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613846.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501429", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501429" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Abcc3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4", "locus": {} } ], "crossref": [ { "id": "cd03244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18595", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18595", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18603", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18603", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767558", "url": "https://www.ncbi.nlm.nih.gov/gene/100767558", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767558", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767558", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KTWIMAF", "url": "https://omabrowser.org/oma/group/KTWIMAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GDJ4", "url": "https://www.orthodb.org/?gene=A0A9J7GDJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF405", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF405", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501429", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501429", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19121", "url": "https://www.rhea-db.org/rhea/19121", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38963", "url": "https://www.rhea-db.org/rhea/38963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60128", "url": "https://www.rhea-db.org/rhea/60128", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDRLCGSGELGSKFWDSNLSVYTDTPDLTPCFQNSLLAWIPCIYLWAALPCYLFYLRNQQRGYIVLTRLSRLKTALGVLLWCVSWVDLFYAFHRLIYGSAPAPVFFITPLVVGITMLLGTLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSATAEGKIADPLRFTTFYIYFALVLCSLILSCFKEKPPLFSPENVDPNPCPEASAGFLSRLSFWWFTKLAILGYRRPLEENDLWTLDEEDCSHKLVQRLLEAWQKQQKRASGPQTAAFEQKTPGEDEVLLRARPKSQKPSFLWALVRTFTSSLLMGVCFKLIQDLLSFINPQLLSILIRFISDPTAPTWWGFLLAGLMFVSSMMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSVLAGVAVIVLLIPLNGAVSMKMRTYQVQQMKFKDSRIKLMNEILNGIKVLKLYAWEPSFLEQVEGIRLSELQLLRKGAYLQAISTFIWVCTPFLVTLITLGVYVSVDENNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQDELDPQCVERETISPGYAITVHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGHVGCGKSSLVSALLGEMEKLEGAVCVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANVFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGHYSALLQHNGSFANFLRNYAPDEDQEGHEVFQDADEEVLLIEDTLSTHTDLTDNEPSMYEVRKQFMRQMSTMSSEGESQNRPVSKRHMNPSEKEMQVTKAKETGALIKDETAETGNVKMSVFWDYAKSVGLYTTLAICLLYAGQSAASIGANVWLSAWANDAVVNGRQNNTSQRLGVYATLGILQGLLVMLSAFTMVVGSVQAARLLHSALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLFNSFYTSISTLVVIVASTPLFIVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIEDFKVLSDKKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGEVGLSVSYALQITLALNWMIRMMSDLESNIIAVERVKEYSKTETEAPWVVEGSRAPEGWPTHGAVEFRNYSVRYRPGLELVLKNLTLRVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEICIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLHSFVSSQPAGLDFECSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFDDCTVLTIAHRLNTIMDYDRVLVLDKGVVAEFDSPTNLIAAGGIFYGMAKDAGLA", "length": 1522, "header": "tr|A0A9J7GDJ4-1|A0A9J7GDJ4_CRIGR Isoform 1 of Canalicular multispecific organic anion transporter 2 OS=Cricetulus griseus OX=10029 GN=Abcc3 PE=3 SV=1 CANONICAL=A0A9J7GDJ4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GDJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4/entry#A0A9J7GDJ4-1", "sequence": { "sequence": "MDRLCGSGELGSKFWDSNLSVYTDTPDLTPCFQNSLLAWIPCIYLWAALPCYLFYLRNQQRGYIVLTRLSRLKTALGVLLWCVSWVDLFYAFHRLIYGSAPAPVFFITPLVVGITMLLGTLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSATAEGKIADPLRFTTFYIYFALVLCSLILSCFKEKPPLFSPENVDPNPCPEASAGFLSRLSFWWFTKLAILGYRRPLEENDLWTLDEEDCSHKLVQRLLEAWQKQQKRASGPQTAAFEQKTPGEDEVLLRARPKSQKPSFLWALVRTFTSSLLMGVCFKLIQDLLSFINPQLLSILIRFISDPTAPTWWGFLLAGLMFVSSMMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSVLAGVAVIVLLIPLNGAVSMKMRTYQVQQMKFKDSRIKLMNEILNGIKVLKLYAWEPSFLEQVEGIRLSELQLLRKGAYLQAISTFIWVCTPFLVTLITLGVYVSVDENNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQDELDPQCVERETISPGYAITVHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGHVGCGKSSLVSALLGEMEKLEGAVCVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANVFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGHYSALLQHNGSFANFLRNYAPDEDQEGHEVFQDADEEVLLIEDTLSTHTDLTDNEPSMYEVRKQFMRQMSTMSSEGESQNRPVSKRHMNPSEKEMQVTKAKETGALIKDETAETGNVKMSVFWDYAKSVGLYTTLAICLLYAGQSAASIGANVWLSAWANDAVVNGRQNNTSQRLGVYATLGILQGLLVMLSAFTMVVGSVQAARLLHSALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLFNSFYTSISTLVVIVASTPLFIVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIEDFKVLSDKKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGEVGLSVSYALQITLALNWMIRMMSDLESNIIAVERVKEYSKTETEAPWVVEGSRAPEGWPTHGAVEFRNYSVRYRPGLELVLKNLTLRVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEICIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLHSFVSSQPAGLDFECSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFDDCTVLTIAHRLNTIMDYDRVLVLDKGVVAEFDSPTNLIAAGGIFYGMAKDAGLA", "length": 1522, "header": "tr|A0A9J7GDJ4-1|A0A9J7GDJ4_CRIGR Isoform 1 of Canalicular multispecific organic anion transporter 2 OS=Cricetulus griseus OX=10029 GN=Abcc3 PE=3 SV=1 CANONICAL=A0A9J7GDJ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767558", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767558", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RX12-1", "protein_name": "ATP-binding cassette sub-family C member 3", "gene_name": "Abcc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRLCGSGELGSKFWDSNLSIYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYLRHHQLGYIVLSWLSRLKTALGVLLWCVSWVDLFYSFHGLIHGSSPAPVFFVTPLVVGITMLLATLLIQYERLRGVQSSGVLIIFWLLCVICAIIPFRSKILSALAEGKILDPFRFTTFYIYFALVFCALILSCFKEKPPLFSPENLDTNPCPEASAGFFSRLSFWWFTRLAILGYRRPLEDRDLWSLSEEDCSHKVVQRLLEAWQKQQNQASRSQTATAEPKIPGEDAVLLKPRPKSKQPSFLRALVRTFTSSLLMSACFNLIQNLLGFVNPQLLSILIRFISDPTAPTWWGFLLAGLMFLSSTMQTLILHQYYHCIFVMALRLRTAIIGVIYRKALVITNSVKRESTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVKQMKFKDSRIKLMSEILNGIKVLKLYAWEPSFLEQVKGIRQSELQLLRKGAYLQAISTFIWICTPFLVTLITLGVYVYVDESNVLDAEKAFVSLSLFNILKIPLNMLPQLISGLTQASVSLKRIQDFLNQNELDPQCVERKTISPGYAITIHNGTFTWAQDLPPTLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGVVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLAGGQVSEMGHYSALLQHDGSFANFLRNYAPDEDQEDHEAALQNANEEVLLLEDTLSTHTDLTDNEPAIYEVRKQFMREMSSLSSEGEVQNRTMPKKHTNSLEKEALVTKTKETGALIKEEIAETGNVKLSVYWDYAKSMGLCTTLSICLLYGGQSAAAIGANVWLSAWSNDAEEHGQQNKTSVRLGVYAALGILQGLLVMLSAFTMVVGAIQAARLLHEALLHNKIRSPQSFFDTTPSGRILNRFSKDIYVIDEVLAPTILMLLNSFFTSISTIMVIVASTPLFMVVVLPLAVLYGFVQRFYVATSRQLKRLESISRSPIFSHFSETVTGTSVIRAYGRIQDFKVLSDTKVDNNQKSSYPYIASNRWLGVHVEFVGNCVVLFAALFAVIGRNSLNPGLVGLSVSYALQVTMALNWMIRMISDLESNIIAVERVKEYSKTKTEAPWVVESNRAPEGWPTRGMVEFRNYSVRYRPGLELVLKNVTVHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIVIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSEEDIWRALELSHLNTFVSSQPAGLDFQCAEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIAAGGIFYGMAKDAGLA", "length": 1523 }, "evidence": [ { "id": "A0A9J7GDJ4", "url": "https://omabrowser.org/oma/group/A0A9J7GDJ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1N3Y6-1", "protein_name": "Multidrug resistance-associated protein 1", "gene_name": "ABCC3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDALCGSGELGSKFWDSNLSLHTDNPDLTPCFQNSLLAWLPCIYLWAALPCYLFYLRGHRQGYIVLSHLSRLKTALGVLLWCVSWADLFYSFHGLVHGWPPAPVFFVTPLVVGVTMLLATLLIQYERLQGVRSSGVLIIFWFLCVVCGIIPFRSKILSALTQGKISDPFRFTTFYIYFALVLSALILSCFREKPPFFSPKNMDPNPCPEAGAGFLSRLSFWWFTKLAILGYRRPLEERDLWSLNKEDRSQMVMQRLLEEWKKQQDQAARRQAAEASGKKLSSEGEVLLEGRPRAPEASFLRALMATFSSSFLLSMGFKLIQDLLSFINPQLLSILIRFISNPTAPTWWGFLVAGLMFVCSVMQTLILHQYFHCIFVMGLRFRTGIIGVIYRKALVITNSVKRESTIGEIVNLMSVDAQRFMDVVPFINLLWSAPLQIILAVYFLWQNLGPSVLAGVALMVLLIPLNGAVAVKMRALQVEQMKFKDSRIKLMSEILGGIKVLKLYAWEPSFLKQVEGIRQDELRLMRKVACLHAISTFIWVCTPFLVTLTTLGVYVSVDKNNVLDAEKAFVSVSLFNILKIPLNMLPQLISNLAQTSVSLKRIQHFLSQDELDPQCVERKTITPGYAVIIHNGTFTWAQDLPPALHSLDIQVPKGALVAVVGPVGCGKSSLLSALLGDMEKLEGKVYMKGSVAYVPQQAWIQNCTLQENVLFGQALDPKRYHKALEACALLADLEVLPGGDQTEIGEKGINLSGGQRQRVSVARAVYSDADIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFVIVLSDGHVSEMGTYSALLQRDGSFANFLRNYAPDEDKEHQEANNRLALEDKEDEEVLMIEDTLSNHTDLTDNEPVTYEVQKQFMRQLSAMSSEGEGQGRSVPRRRLGAAEKVVPATEAKASHVLTQEEKTELGTVKLSVYLDYAKAVGLWTALVICLLYGGQSAAAIGANVWLSAWTDEAAVDSQQNSTSYRLGVYAALGILQGLLVMLSAITMAVGGVQAARLLHQALLHNKMRSPQSFFDTTPSGRILNRFSKDIYVIDELLAPTILMLLNSFYNSISTLVVIVASTPLFAVVILPLAVLYLFVQRFYVATSRQLKRLESVSRSPIYSHFSETVTGSSVIRAYGRSQDFETINDAKVDTNQKSCYPYIASNRWLGIRVEFVGNCVVLFAALFAVTERSSLSPGLVGLSVSYALQVTLALNWMIRTISDLESNIVAVERVKEYSKTEMEAPWVVEGSRPPAGWPLKGEVEFRNYSVRYRPGLELVLKDLSLRVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIYIDGLNVADIGLHDLRSKLTIIPQDPILFSGTLRMNLDPFGCYSEEDMWQALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDDLIQATIRTQFETCTVLTIAHRLNTIMDYTRVLVLDKGTIAEFDSPSNLIAARGIFYGMARDAGLA", "length": 1529 }, "evidence": [ { "id": "A0A9J7GDJ4", "url": "https://omabrowser.org/oma/group/A0A9J7GDJ4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NM51-1", "protein_name": "ATP binding cassette subfamily C member 3", "gene_name": "ABCC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAFCGSRFWDANLSIHTDSPDLTPCFQNTILAWIPSIYLWTALPFYLLYLKRSKRGYIVLTMLSRFKTLFGVLLWCVSWADLFYSFHELLQSRTPPPVYFVTPLVIGITVLLATLLIQYERLRGVQSSGVLIIFWFLSVLCAVAPFRSKIMTTTAQNHVNERFRSATFYIYFVLLIVELILSCFKEKPPFFSPANTDPNPSPELTSGFLSRLTFWWFTSFAILGYKKPLEEKDLWSLNEDDISKNIVQKLSREWDKEKAECKQKEDVTYRKKSNHALNHVGDGPEEAEVLIRDKRHNRKPSFLKALMRTFGPYFLIGSFFKLIQDLLSFVNPQLLSVLISFVKDKDAPTWWGFLIAALMFACAVLQTLILHQHFQYCFVTGMRLRTGIIGVIYRKSLVITNSAKRSSTVGEIVNLMSVDAQRFMDLVTFLNMLWSAPLQTCLALYFLWQALGPSVLAGVAVMVLLIPFNSAVAIKTRAFQVEQMRYKDSRIKLMNEILGGIKVLKLYAWEPSFSEKVLEMRKNELRVLKKSAYLNSLSNFAWISSPFLVALTTFAVYVLVDEKNTLDAEKAFVSLSLFNILKFPLTMLPQVISNIAQTSVSLKRIQQFLSHDELDPNCVERKVIAPGYAISVKNATFSWGKELKPSLKDINLLVPSGALVAVVGHVGCGKSSLVSALLGEMEKLEGEVAVKGSVAYVPQQAWIQNATLKDNILFGQAPNEQKYQNVLEACALKTDLEVLPGGDHTEIGEKGINLSGGQRQRVSLARAVFSSSDIYLLDDPLSAVDSHVAKHIFDQVIGPDGVLKGKTRILVTHGIGFLPQVDHIVVLADGKISEMGSYQELLKQNKAFAEFLRNYALDENTEEDELTMMEEEEVLLAEDTLSIHTDLADNEPVTNEVRKQFLRQLSVISSEGGECPNKMSTKRRVAEKKPAEPPLPRRNPNEKLIQAETTEVGTVKLTVFWQYMKAVSPVISLIICFLYCCQNAASIGANVWLSDWTNEPVINGTQHNTSMRIGVYAALGLLQGFIVFVSSFTLAMGGINAARKLHTALLENKFHTPQSFYDTTPTGRIINRFSKDIFVIDEVIPPTILMFLGTFFASLSTMIVIVASTPLFAVVVVPLAVLYYFVQRFYVATSRQLKRLESVSRSPIYSHFSETISGTSVIRAYQRERSFIDISDLKVDENQKSYYPGIISNRWLGIRVEFVGNCIVLFAALFAVIGKSSLNAGLVGLSVSYALQVTMALNWMVRTTSDLETNIVAVERIKEYSETETEAPWIIEDKRPPADWPSRGELEFVGYSVRYRKGLDLVLKDLNLRVHGGEKIGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGVRISEIGLHDLRSRLTIIPQDPVLFSGTLRMNLDPFNKYSDEEVWKALELSHLKRFVSSQPSMLEFECSEGGENLSVGQRQLVCLARALLRKTRVLILDEATAAIDLETDDLIQMTIRTQFEDCTVLTIAHRLNTIMDYTRILVLDNGTIAEFDTPANLIASKGIFYGMAKDAGLV", "length": 1529 }, "evidence": [ { "id": "A0A9J7GDJ4", "url": "https://omabrowser.org/oma/group/A0A9J7GDJ4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O15438-1", "protein_name": "ATP-binding cassette sub-family C member 3", "gene_name": "ABCC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDALCGSGELGSKFWDSNLSVHTENPDLTPCFQNSLLAWVPCIYLWVALPCYLLYLRHHCRGYIILSHLSKLKMVLGVLLWCVSWADLFYSFHGLVHGRAPAPVFFVTPLVVGVTMLLATLLIQYERLQGVQSSGVLIIFWFLCVVCAIVPFRSKILLAKAEGEISDPFRFTTFYIHFALVLSALILACFREKPPFFSAKNVDPNPYPETSAGFLSRLFFWWFTKMAIYGYRHPLEEKDLWSLKEEDRSQMVVQQLLEAWRKQEKQTARHKASAAPGKNASGEDEVLLGARPRPRKPSFLKALLATFGSSFLISACFKLIQDLLSFINPQLLSILIRFISNPMAPSWWGFLVAGLMFLCSMMQSLILQHYYHYIFVTGVKFRTGIMGVIYRKALVITNSVKRASTVGEIVNLMSVDAQRFMDLAPFLNLLWSAPLQIILAIYFLWQNLGPSVLAGVAFMVLLIPLNGAVAVKMRAFQVKQMKLKDSRIKLMSEILNGIKVLKLYAWEPSFLKQVEGIRQGELQLLRTAAYLHTTTTFTWMCSPFLVTLITLWVYVYVDPNNVLDAEKAFVSVSLFNILRLPLNMLPQLISNLTQASVSLKRIQQFLSQEELDPQSVERKTISPGYAITIHSGTFTWAQDLPPTLHSLDIQVPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGKVHMKGSVAYVPQQAWIQNCTLQENVLFGKALNPKRYQQTLEACALLADLEMLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDADIFLLDDPLSAVDSHVAKHIFDHVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQVSEMGPYPALLQRNGSFANFLCNYAPDEDQGHLEDSWTALEGAEDKEALLIEDTLSNHTDLTDNDPVTYVVQKQFMRQLSALSSDGEGQGRPVPRRHLGPSEKVQVTEAKADGALTQEEKAAIGTVELSVFWDYAKAVGLCTTLAICLLYVGQSAAAIGANVWLSAWTNDAMADSRQNNTSLRLGVYAALGILQGFLVMLAAMAMAAGGIQAARVLHQALLHNKIRSPQSFFDTTPSGRILNCFSKDIYVVDEVLAPVILMLLNSFFNAISTLVVIMASTPLFTVVILPLAVLYTLVQRFYAATSRQLKRLESVSRSPIYSHFSETVTGASVIRAYNRSRDFEIISDTKVDANQRSCYPYIISNRWLSIGVEFVGNCVVLFAALFAVIGRSSLNPGLVGLSVSYSLQVTFALNWMIRMMSDLESNIVAVERVKEYSKTETEAPWVVEGSRPPEGWPPRGEVEFRNYSVRYRPGLDLVLRDLSLHVHGGEKVGIVGRTGAGKSSMTLCLFRILEAAKGEIRIDGLNVADIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGSYSEEDIWWALELSHLHTFVSSQPAGLDFQCSEGGENLSVGQRQLVCLARALLRKSRILVLDEATAAIDLETDNLIQATIRTQFDTCTVLTIAHRLNTIMDYTRVLVLDKGVVAEFDSPANLIAARGIFYGMARDAGLA", "length": 1527 }, "evidence": [ { "id": "A0A9J7GDJ4", "url": "https://omabrowser.org/oma/group/A0A9J7GDJ4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88563-1", "protein_name": "ATP-binding cassette sub-family C member 3", "gene_name": "Abcc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRLCGSGELGSKFWDSNLTVYTNTPDLTPCFQNSLLAWVPCIYLWAALPCYLFYLRHHRLGYIVLSCLSRLKTALGVLLWCISWVDLFYSFHGLVHGSSPAPVFFITPLLVGITMLLATLLIQYERLRGVRSSGVLIIFWLLCVICAIIPFRSKILLALAEGKILDPFRFTTFYIYFALVLCAFILSCFQEKPPLFSPENLDTNPCPEASAGFFSRLSFWWFTKLAILGYRRPLEDSDLWSLSEEDCSHKVVQRLLEAWQKQQTQASGPQTAALEPKIAGEDEVLLKARPKTKKPSFLRALVRTFTSSLLMGACFKLIQDLSPSSTHSCSASSSGLFRPHGPYWWGFLLAGLMFVSSTMQTLILHQHYHCIFVMALRIRTAIIGVIYRKALTITNSVKREYTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAGVAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQGELQLLRKGAYLQAISTFIWVCTPFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIPLNLLPQLISGMTQTSVSLKRIQDFLNQDELDPQCVERKTISPGRAITIHNGTFSWSKDLPPTLHSINIQIPKGALVAVVGPVGCGKSSLVSALLGEMEKLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEIGEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVTHGISFLPQTDFIIVLADGQITEMGHYSELLQHDGSFANFLRNYAPDENQEANEGVLQHANEEVLLLEDTLSTHTDLTDTEPAIYEVRKQFMREMSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKETGALIKEEIAETGNVKLSVYWDYAKSVGLCTTLFICLLYAGQNAVAIGANVWLSAWTNDVEEHGQQNNTSVRLGVYATLGILQGLLVMLSAFTMVVGAIQAARLLHTALLHNQIRAPQSFFDTTPSGRILNRFSKDIYVIHEVLAPTILMLFNSFYTSISTIVVIVASTPLFCVVVLPLAVFYGFVQRFYVATSRQLKRLESVSRSPIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTYPYIASNRWLGVHVEFVGNCVVLFSALFAVIGRNSLNPGLVGLSVSYALQVTLSLNWMIRTLSDLESNIIAVERVKEYSKTETEAPWVLESNRAPEGWPRSGVVEFRNYSVRYRPGLELVLKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIFIDGLNVAHIGLHDLRSQLTIIPQDPILFSGTLRMNLDPFGRYSDEDIWRTLELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVCLARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGVVAEFDSPVNLIAAGGIFYGMAKDAGLA", "length": 1522 }, "evidence": [ { "id": "A0A9J7GDJ4", "url": "https://omabrowser.org/oma/group/A0A9J7GDJ4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P14772-1", "protein_name": "Bile pigment transporter 1", "gene_name": "BPT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSLEVVDGCPYGYRPYPDSGTNALNPCFISVISAWQAVFFLLIGSYQLWKLYKNNKVPPRFKNFPTLPSKINSRHLTHLTNVCFQSTLIICELALVSQSSDRVYPFILKKALYLNLLFNLGISLPTQYLAYFKSTFSMGNQLFYYMFQILLQLFLILQRYYHGSSNERLTVISGQTAMILEVLLLFNSVAIFIYDLCIFEPINELSEYYKKNGWYPPVHVLSYITFIWMNKLIVETYRNKKIKDPNQLPLPPVDLNIKSISKEFKANWELEKWLNRNSLWRAIWKSFGRTISVAMLYETTSDLLSVVQPQFLRIFIDGLNPETSSKYPPLNGVFIALTLFVISVVSVFLTNQFYIGIFEAGLGIRGSLASLVYQKSLRLTLAERNEKSTGDILNLMSVDVLRIQRFFENAQTIIGAPIQIIVVLTSLYWLLGKAVIGGLVTMAIMMPINAFLSRKVKKLSKTQMKYKDMRIKTITELLNAIKSIKLYAWEEPMMARLNHVRNDMELKNFRKIGIVSNLIYFAWNCVPLMVTCSTFGLFSLFSDSPLSPAIVFPSLSLFNILNSAIYSVPSMINTIIETSVSMERLKSFLLSDEIDDSFIERIDPSADERALPAIEMNNITFLWKSKEVLTSSQSGDNLRTDEESIIGSSQIALKNIDHFEAKRGDLVCVVGRVGAGKSTFLKAILGQLPCMSGSRDSIPPKLIIRSSSVAYCSQESWIMNASVRENILFGHKFDQDYYDLTIKACQLLPDLKILPDGDETLVGEKGISLSGGQKARLSLARAVYSRADIYLLDDILSAVDAEVSKNIIEYVLIGKTALLKNKTIILTTNTVSILKHSQMIYALENGEIVEQGNYEDVMNRKNNTSKLKKLLEEFDSPIDNGNESDVQTEHRSESEVDEPLQLKVTESETEDEVVTESELELIKANSRRASLATLRPRPFVGAQLDSVKKTAQKAEKTEVGRVKTKIYLAYIKACGVLGVVLFFLFMILTRVFDLAENFWLKYWSESNEKNGSNERVWMFVGVYSLIGVASAAFNNLRSIMMLLYCSIRGSKKLHESMAKSVIRSPMTFFETTPVGRIINRFSSDMDAVDSNLQYIFSFFFKSILTYLVTVILVGYNMPWFLVFNMFLVVIYIYYQTFYIVLSRELKRLISISYSPIMSLMSESLNGYSIIDAYDHFERFIYLNYEKIQYNVDFVFNFRSTNRWLSVRLQTIGATIVLATAILALATMNTKRQLSSGMVGLLMSYSLEVTGSLTWIVRTTVTIETNIVSVERIVEYCELPPEAQSINPEKRPDENWPSKGGIEFKNYSTKYRENLDPVLNNINVKIEPCEKVGIVGRTGAGKSTLSLALFRILEPTEGKIIIDGIDISDIGLFDLRSHLAIIPQDAQAFEGTVKTNLDPFNRYSEDELKRAVEQAHLKPHLEKMLHSKPRGDDSNEEDGNVNDILDVKINENGSNLSVGQRQLLCLARALLNRSKILVLDEATASVDMETDKIIQDTIRREFKDRTILTIAHRIDTVLDSDKIIVLDQGSVREFDSPSKLLSDKTSIFYSLCEKGGYLK", "length": 1559 }, "evidence": [ { "id": "A0A9J7GDJ4", "url": "https://omabrowser.org/oma/group/A0A9J7GDJ4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9LZJ5-1", "protein_name": "ABC transporter C family member 14", "gene_name": "ABCC14", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRWLSSTWLSDLSCSSSSVIEPSSSLPAPIQWLRFILLSPCPQRLLSSTVDVLFLLILFFFAIQKLCSSSSSRTNGEADITKPLLGRRTRTRTTGLFKTTVVVTIVLSFCSLVLCVSAFFTTRTKLKLVDTLFWLIHAVTNVVIAVLVLHLKRFASPSHPLTLRIYWVFNFVVTTLFTVSGILHLLSDDPAAASLRADDVASFISFPLTAVLLLVSIKGSTGVVVTTSNVTAPAKSNDVVVEKSENVSLYASASFISKTFWLWMNPLLRKGYKSPLNLDQVPTLSPEHRAEKLATLFESKWPKPQENSRNPVRTTLIRCFWKEIAFTAVLAIIRLSVIYVGPVLIQSFVDFTSGKRSSPSQGYYLVLILLIAKFVEVLSTHQFNFNSQKLGMLIRSTLITALYKKGLKLTGSARQNHGVGQIVNYMAVDAQQLSDMMLQLHAIWLMPLQVAAAIVLLYNTLGPSVVTTVIGLTGIFVFILLGTKRNNRYQFSLMMNRDSRMKATNEMLNYMRVIKFQAWEDHFNERILKFREMEFGWLSKFLYSIAGNIIVLWSTPVLISALTFTTAVFLGVKLDAGTVFTTTTIFKILQEPIRTFPQSMISLSQAMISLGRLDAYMMSRELSEETVERSQGCDGNVAVEIKDGSFSWDDEDDEPAIENINFEVKKGELAAIVGTVGSGKSSLLASVLGEMHKLSGKVRVCGTTAYVAQTSWIQNGTVQDNILFGLPMNRSKYNEVLKVCCLEKDMQIMEFGDQTEIGERGINLSGGQKQRIQLARAVYQESDVYLLDDVFSAVDAHTGSDIFKKCVRGALKGKTILLVTHQVDFLHNVDRILVMRDGMIVQSGKYDELVSSGLDFGELVAAHETSMELVEAGSASATAANVPMASPITQRSISIESPRQPKSPKVHRTTSMESPRVLRTTSMESPRLSELNDESIKSFLGSNIPEDGSRLIKEEEREVGQVSFQVYKLYSTEAYGWWGMILVVFFSVAWQASLMASDYWLAYETSAKNEVSFDATVFIRVYVIIAAVSIVLVCLRAFYVTHLGLKTAQIFFKQILNSLVHAPMSFFDTTPSGRILSRASTDQTNVDIFIPFMIGLVATMYTTLLSIFIVTCQYAWPTVFFIIPLGWLNIWYRGYYLASSRELTRLDSITKAPVIHHFSESIAGVMTIRAFKKQPMFRQENVKRVNANLRMDFHNNGSNEWLGFRLELIGSWVLCISALFMVMLPSNIIKPENVGLSLSYGLSLNGVLFWAIYLSCFIENKMVSVERIKQFTDIPAEAKWEIKESRPPPNWPYKGNIRLEDVKVRYRPNTPLVLKGLTIDIKGGEKIGVVGRTGSGKSTLIQVLFRLVEPSGGKIIIDGIDICTLGLHDLRSRFGIIPQEPVLFEGTVRSNIDPTEKYSDEEIWKSLERCQLKDVVASKPEKLDSLVADNGENWSVGQRQLLCLGRVMLKRSRILFLDEATASVDSQTDAMIQKIIREDFSDCTIISIAHRIPTVMDCDRVLVIDAGKAKEYDSPVRLLERQSLFAALVQEYALRSAGI", "length": 1539 }, "evidence": [ { "id": "A0A9J7GDJ4", "url": "https://omabrowser.org/oma/group/A0A9J7GDJ4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4" } ], "pmid": "" }, { "name": "ABC-type glutathione S-conjugate transporter activity", "id": "GO:0015431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015431", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281399", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2QC50", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QC50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5Q5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIPPQEASARRREIEDKLKKEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLILDLISGDEELEVQEDVTLEHLPESVLQDVIRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGTIRKAQNLLKQYSQHGLDGKKGGSNLIPLEGHEHDFRVKHLSEALNDKHGPLAGRDDMLDVETDAYIHCVSAFVKLAQSEYHLLTLIIPELHQKRTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETVGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAVFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQIYQRSWLKVTDYISEKSLPVFQPGVKLRDKERQVIKERFKGFNDGLEELCKIQKAWAIPDTEQRDKIRQAQKTMVKESYGAFLHRYGNVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA", "length": 707, "header": "tr|A0A9J7GDJ5-1|A0A9J7GDJ5_CRIGR Isoform 1 of Exocyst complex component 7 OS=Cricetulus griseus OX=10029 GN=Exoc7 PE=3 SV=1 CANONICAL=A0A9J7GDJ5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2QC50-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5/entry#A0A8C2QC50-1", "sequence": { "sequence": "MIPPQEASARRREIEDKLKKEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLILDLISGDEELEVQEDVTLEHLPESVLQDVIRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGRDDMLDVETDAYIHCVSAFVKLAQSEYHLLTLIIPELHQKRTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETVGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAVFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQIYQRSWLKVTDYISEKSLPVFQPGVKLRDKERQVIKERFKGFNDGLEELCKIQKAWAIPDTEQRDKIRQAQKTMVKESYGAFLHRYGNVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA", "length": 653, "header": "tr|A0A8C2QC50-1|A0A8C2QC50_CRIGR Computationally mapped isoform of Exocyst complex component 7 OS=Cricetulus griseus OX=10029 GN=Exoc7 PE=3 SV=1 CANONICAL=A0A9J7GDJ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5/entry#A0A9J7GDJ5-1", "sequence": { "sequence": "MIPPQEASARRREIEDKLKKEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLILDLISGDEELEVQEDVTLEHLPESVLQDVIRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGTIRKAQNLLKQYSQHGLDGKKGGSNLIPLEGHEHDFRVKHLSEALNDKHGPLAGRDDMLDVETDAYIHCVSAFVKLAQSEYHLLTLIIPELHQKRTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETVGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAVFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQIYQRSWLKVTDYISEKSLPVFQPGVKLRDKERQVIKERFKGFNDGLEELCKIQKAWAIPDTEQRDKIRQAQKTMVKESYGAFLHRYGNVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA", "length": 707, "header": "tr|A0A9J7GDJ5-1|A0A9J7GDJ5_CRIGR Isoform 1 of Exocyst complex component 7 OS=Cricetulus griseus OX=10029 GN=Exoc7 PE=3 SV=1 CANONICAL=A0A9J7GDJ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5/entry#A0A9J7GDL7-1", "sequence": { "sequence": "MIPPQEASARRREIEDKLKKEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLILDLISGDEELEVQEDVTLEHLPESVLQDVIRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGHEHDFRVKHLSEALNDKHGPLAGRDDMLDVETDAYIHCVSAFVKLAQSEYHLLTLIIPELHQKRTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETVGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAVFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQIYQRSWLKVTDYISEKSLPVFQPGVKLRDKERQVIKERFKGFNDGLEELCKIQKAWAIPDTEQRDKIRQAQKTMVKESYGAFLHRYGNVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA", "length": 676, "header": "tr|A0A9J7GDL7-1|A0A9J7GDL7_CRIGR Computationally mapped isoform of Exocyst complex component 7 OS=Cricetulus griseus OX=10029 GN=Exoc7 PE=3 SV=1 CANONICAL=A0A9J7GDJ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5/entry#A0A9J7H5Q5-1", "sequence": { "sequence": "MIPPQEASARRREIEDKLKKVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLILDLISGDEELEVQEDVTLEHLPESVLQDVIRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGTIRKAQNLLKQYSQHGLDGKKGGSNLIPLEGHEHDFRVKHLSEALNDKHGPLAGRDDMLDVETDAYIHCVSAFVKLAQSEYHLLTLIIPELHQKRTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETVGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAVFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQIYQRSWLKVTDYISEKSLPVFQPGVKLRDKERQVIKERFKGFNDGLEELCKIQKAWAIPDTEQRDKIRQAQKTMVKESYGAFLHRYGNVPFTKNPEKYIKYRVEQVGDMIDRLFDTSA", "length": 685, "header": "tr|A0A9J7H5Q5-1|A0A9J7H5Q5_CRIGR Computationally mapped isoform of Exocyst complex component 7 OS=Cricetulus griseus OX=10029 GN=Exoc7 PE=3 SV=1 CANONICAL=A0A9J7GDJ5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5/entry#A0A9J7KBF5-1", "sequence": { "sequence": "MIPPQEASARRREIEDKLKKEEETLSFIRDSLEKSDQLTKNMVSILSSFESRLMKLENSIIPVHKQTENLQRLQENVEKTLSCLDHVISYYHVASDTEKIIREGPTGRLEEYLGSMAKIQKAVEYFQDNSPDSPELNKVKLLFERGKESLESEFRSLMTRHSKVVSPVLILDLISGDEELEVQEDVTLEHLPESVLQDVIRISRWLVEYGRNQDFMNVYYQIRSSQLDRSIKGLKEHFRKSSSSSGVPYSPAIPNKRKDTPTKKPIKRPGTIRKAQNLLKQYSQHGLDGKKGGSNLIPLEGHEHDFRVKHLSEALNDKHGPLAGRDDMLDVETDAYIHCVSAFVKLAQSEYHLLTLIIPELHQKRTFDSLIQDALDGLMLEGENIVSAARKAIIRHDFSTVLTVFPILRHLKQTKPEFDQVLQGTAASTKNKLPGLITSMETVGAKALEDFADNIKNDPDKEYNMPKDGTVHELTSNAILFLQQLLDFQETAGAMLASQETSSSATSYSSEFSKRLLSTYICKVLGNLQLNLLSKSKVYEDPALSAVFLHNNYNYILKSLEKSELIQLVAVTQKTAERSYREHIEQQIQIYQRR", "length": 594, "header": "tr|A0A9J7KBF5-1|A0A9J7KBF5_CRIGR Computationally mapped isoform of Exocyst complex component 7 OS=Cricetulus griseus OX=10029 GN=Exoc7 PE=3 SV=1 CANONICAL=A0A9J7GDJ5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 106, "start_aa": "Thr", "end_pos": 106, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr106", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754030", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754030", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5" } ], "pmid": "" }, { "name": "Flemming body", "id": "GO:0090543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090543", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5" } ], "pmid": "" }, { "name": "exocyst", "id": "GO:0000145", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000145", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5" } ], "pmid": "" }, { "name": "exocytosis", "id": "GO:0006887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GDJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDJ5" }, { "id": "PF03081", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exocyst complex subunit Exo70 C-terminal", "eco_id": "ECO_0000259", "start_pos": 336, "end_pos": 700, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 106 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GDN6-1", "uniprot_ac": "A0A9J7GDN6", "uniprot_id": "A0A9J7GDN6_CRIGR", "mass": { "chemical_mass": 123429.0, "monoisotopic_mass": 123429.0 }, "refseq": { "ac": "XP_027281448", "name": "protein unc-13 homolog D", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281448" }, "gene_names": [ { "name": "Unc13d", "type": "recommended", "evidence": [ { "id": "A0A9J7GDN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDN6" } ] }, { "name": "Unc13d", "type": "synonym", "evidence": [ { "id": "XP_027281448", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281448" } ] } ], "protein_names": [ { "name": "Protein unc-13 homolog D", "type": "recommended", "evidence": [ { "id": "A0A9J7GDN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDN6/entry#names_and_taxonomy" } ] }, 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"PF23445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281671", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281671", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "13065", "url": "https://www.rhea-db.org/rhea/13065", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GDX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKSNDCLFSMDNLFFSSPNETENLPVKEKSLDWFLPPAPLISEIPDSQELEEEIESYKLSGQGKMPKMLTSNLKIINEDKNCILPTQKFHFPCNVRKQDYLNLGGSSNKDSSRVAGKLVYGSSQKYKDHMGTEIPPGDSRLPKASEDMGEGTQAFKERLFRTCDNIHECDYANGNTDLDSHISSAKLAQAKINKEKSWNCGNSKQKLQYSTNKLKGNDTFSASGIGENIFPVPSFSVASQPCDSQGILEPNGLGSLKAVTEIPAKFRSIFKEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNMKIVYMAPIKALCSQRFDDWKEKFGPMGLNCKELTGDTVMDDLFEIQHANIIMTTPEKWDTMTRKWRANSLVQLVRLFLIDEVHIIKDENRGPTLEVVVSRMKTIQSLSRTLQNASPVPMRFVAVSATIPNAEDVAEWLSDGERPAVCLKMDESHRPVRLQKVILGFPCSSNQTEFKFDLALNYKVYGVIRTYSDQKPTLVFCATRKGVQQAASVLVKDAKFIISVEQRLRLQKSAYSIRDSKLKDVLVYGVGYHHAGMELSDRKLVEELFTSGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYTGGMFEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTREKYVQMLACNDTVESSLHRHLIEHLNAEIVLHTITDVSIALDWIRSTLLYIRALKNPSHYGFVSGLNKDGIEAKLQELCLKNLKDLSSLDLIKMDEDVYFKPTEAGRLMAWYYITFETVKKFYTISGKETLSDLISMIASCNEFLDVQLRINEKRTLNTLNKDPNRVTIRFPMEGRIKTREMKVNCLIQAQLGCIPIQDFALTQDTSKIFRNGSRIARWLSDFVASQEKKFAVLLNSVILAKCFKCKLWENSRHVSKQLDKIGISLSNTMVNAGLTSFKKIEEANAREIELILSRHPPFGTQIKEAVVYLPKYGLEVEQIARYSDIKAEILVTVTLRNFKQLQTKRTAPDAHYTTLIIGDADNQVVFKHKIMDSVLLKSGNWAKKIDVKRALTSEDLSINLISSDYVGLDIQQKFTVFYLGTRMPVNQTVMQRRLETDISHAKYSNRAIVAGSSQGMATCKKPGNRECNHHCKNKHTCGHDCCKIGVSQKPEVKESAMSSYLSDLKSRNAVSSLPPVKRLKIQMNKSQNVDLKEFGFTPRPSLSSISRSESLNIPQLPILEQWTEHEVYEKVQESSAYHDKGKPSEVLDVNFELGNEVWDDFDDESLIEVMNFSAGAENTAVSGFGDSCDSSPRGSKLPFQKSRSKFQREISNSFVSSHEKPSIYLSDCAMSKFGPSPVAELPQQAGNANLVNLQERRQPPLSPEIERICFTRPKNIPQSLNFKEVDIFIGNSDSKKEIDLSKYYPDDAAEEMKALLGIFNGIF", "length": 1434, "header": "tr|A0A9J7GDX9-1|A0A9J7GDX9_CRIGR Isoform 1 of Probable ATP-dependent DNA helicase HFM1 OS=Cricetulus griseus OX=10029 GN=Hfm1 PE=3 SV=1 CANONICAL=A0A9J7GDX9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GDX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9/entry#A0A9J7GDX9-1", "sequence": { "sequence": "MLKSNDCLFSMDNLFFSSPNETENLPVKEKSLDWFLPPAPLISEIPDSQELEEEIESYKLSGQGKMPKMLTSNLKIINEDKNCILPTQKFHFPCNVRKQDYLNLGGSSNKDSSRVAGKLVYGSSQKYKDHMGTEIPPGDSRLPKASEDMGEGTQAFKERLFRTCDNIHECDYANGNTDLDSHISSAKLAQAKINKEKSWNCGNSKQKLQYSTNKLKGNDTFSASGIGENIFPVPSFSVASQPCDSQGILEPNGLGSLKAVTEIPAKFRSIFKEFPYFNYIQSKAFDDLLYTDRNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNMKIVYMAPIKALCSQRFDDWKEKFGPMGLNCKELTGDTVMDDLFEIQHANIIMTTPEKWDTMTRKWRANSLVQLVRLFLIDEVHIIKDENRGPTLEVVVSRMKTIQSLSRTLQNASPVPMRFVAVSATIPNAEDVAEWLSDGERPAVCLKMDESHRPVRLQKVILGFPCSSNQTEFKFDLALNYKVYGVIRTYSDQKPTLVFCATRKGVQQAASVLVKDAKFIISVEQRLRLQKSAYSIRDSKLKDVLVYGVGYHHAGMELSDRKLVEELFTSGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYTGGMFEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTREKYVQMLACNDTVESSLHRHLIEHLNAEIVLHTITDVSIALDWIRSTLLYIRALKNPSHYGFVSGLNKDGIEAKLQELCLKNLKDLSSLDLIKMDEDVYFKPTEAGRLMAWYYITFETVKKFYTISGKETLSDLISMIASCNEFLDVQLRINEKRTLNTLNKDPNRVTIRFPMEGRIKTREMKVNCLIQAQLGCIPIQDFALTQDTSKIFRNGSRIARWLSDFVASQEKKFAVLLNSVILAKCFKCKLWENSRHVSKQLDKIGISLSNTMVNAGLTSFKKIEEANAREIELILSRHPPFGTQIKEAVVYLPKYGLEVEQIARYSDIKAEILVTVTLRNFKQLQTKRTAPDAHYTTLIIGDADNQVVFKHKIMDSVLLKSGNWAKKIDVKRALTSEDLSINLISSDYVGLDIQQKFTVFYLGTRMPVNQTVMQRRLETDISHAKYSNRAIVAGSSQGMATCKKPGNRECNHHCKNKHTCGHDCCKIGVSQKPEVKESAMSSYLSDLKSRNAVSSLPPVKRLKIQMNKSQNVDLKEFGFTPRPSLSSISRSESLNIPQLPILEQWTEHEVYEKVQESSAYHDKGKPSEVLDVNFELGNEVWDDFDDESLIEVMNFSAGAENTAVSGFGDSCDSSPRGSKLPFQKSRSKFQREISNSFVSSHEKPSIYLSDCAMSKFGPSPVAELPQQAGNANLVNLQERRQPPLSPEIERICFTRPKNIPQSLNFKEVDIFIGNSDSKKEIDLSKYYPDDAAEEMKALLGIFNGIF", "length": 1434, "header": "tr|A0A9J7GDX9-1|A0A9J7GDX9_CRIGR Isoform 1 of Probable ATP-dependent DNA helicase HFM1 OS=Cricetulus griseus OX=10029 GN=Hfm1 PE=3 SV=1 CANONICAL=A0A9J7GDX9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761873", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761873", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "3'-5' DNA helicase activity", "id": "GO:0043138", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043138", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1097, "end_pos": 1099, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1195, "end_pos": 1197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1282, "end_pos": 1284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 882, "end_pos": 884, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "13065", "name": "", "equation": "ATP + H2O = ADP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H6T7-1", "G3H7V9-1", "G3HCT4-1", "G3HIC5-1", "G3HIL5-1", "A0A061IR73-1", "G3GXG9-1", "G3I8R9-1", "G3HH18-1", "A0A9J7FU33-1", "G3I2I1-1", "A0A9J7FTT2-1", "G3IEZ7-1", "G3HKQ8-1", "G3HMB1-1", "G3HCV0-1", "G3HX41-1", "G3I6K0-1", "G3HTL1-1", "G3HU77-1", "G3HAH5-1", "G3HJ88-1", "G3GSH5-1", "G3GY12-1", "G3I5T3-1", "G3I6L7-1", "G3H484-1", "G3IJD1-1", "G3I008-1", "A0A8C2M596-1", "G3IG24-1", "A0A9J7F876-1", "A0A9J7FI42-1", "A0A9J7G1N4-1", "A0A061IJA4-1", "A0A9J7FPD0-1", "A0A9J7G7V8-1", "A0A9J7JQY5-1", "A0A8C2MCA5-1", "A0A9J7H2D3-1", "A0A9J7G2T1-1", "G3HBU1-1", "G3HUZ6-1", "G3HWS4-1", "A0A9J7HCU3-1", "A0A3L7HMZ7-1", "A0A9J7K3T5-1", "A0A8C2MMI4-1", "A0A9J7GRQ0-1", "A0A8C2N055-1", "A0A8C2QHV1-1", "A0A8C2QM19-1", "A0A8C2M4F5-1", "A0A9J7FJ23-1", "A0A9J7FUH6-1", "A0A9J7G659-1", "A0A9J7K2R5-1", "A0A8C2MB35-1", "G3I478-1", "A0A9J7H1K5-1", "A0A8C2QH91-1", "A0A9J7JQ85-1", "A0A9J7K381-1", "A0A061HU45-1", "A0A061I456-1", "A0A061ICN7-1", "A0A061IKS3-1", "A0A3L7H9D4-1", "A0A9J7H2L4-1", "A0A8C2LZL3-1", "A0A8C2M796-1", "A0A8C2MCS3-1", "A0A8C2MPK3-1", "A0A8C2MQ86-1", "A0A3L7ILF9-1", "A0A3L7INC4-1", "A0A8C2LCW6-1", "A0A8C2LRD7-1", "A0A8C2LSK1-1", "A0A9J7JSD0-1", "P18279-1", "P48975-1", "A0A8C2MVH8-1", "A0A8C2MWE0-1", "A0A8C2MYM8-1", "A0A8C2N236-1", "A0A9J7FYM8-1", "A0A8C2QLX9-1", "A0A8C2QNE7-1", "A0A9J7F9W3-1", "A0A9J7JR19-1", "A0A9J7FPK3-1", "A0A9J7JMF4-1", "A0A9J7FV95-1", "A0A9J7FXI2-1", "A0A9J7G412-1", "A0A9J7G5W9-1", "A0A9J7GCV1-1", "A0A9J7H3Y2-1", "A0A9J7GF88-1", "A0A9J7GHR4-1", "A0A9J7GID0-1", "A0A9J7JVX0-1", "A0A9J7KF39-1", "A0A9J7H4G1-1", "A0A9J7H9J6-1", "A0A9J7JEW1-1", "A0A9J7JIL5-1", "A0A9J7FCH5-1", "A0A8C2MFM1-1", "A0A8C2MWH4-1", "A0A8C2LG83-1", "A0A9J7GDX9-1", "A0A9J7H2C5-1", "A0A9J7GN75-1", "A0A9J7JT79-1", "A0A9J7K1D9-1", "A0A061IIX2-1", "A0A8C2M474-1", "A0A8C2N386-1", "A0A9J7GR00-1", "O35501-1", "P18708-1", "P19378-1", "P46633-1", "Q60452-1", "A0A8C2LBG1-1", "A0A8C2LR22-1", "A0A8C2M4G0-1", "A0A8C2M6G7-1", "G3HCS2-1", "P70099-1", "A0A9J7FI19-1", "A0A9J7G6M1-1", "A0A9J7FJ37-1", "A0A9J7G7R5-1", "A0A8C2MAV3-1", "A0A8C2N184-1", "A0A9J7F1E5-1", "A0A8C2MBY6-1", "A0A9J7JLC6-1" ], "evidence": [ { "id": "13065", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/13065" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HU45", "gene_name": "Ercc6l", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061HU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HU45" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A061HU45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HU45" } ] } ] }, { "uniprot_ac": "A0A061I456", "gene_name": "Ruvbl2", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061I456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I456" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A061I456", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I456" } ] } ] }, { "uniprot_ac": "A0A061ICN7", "gene_name": "Mtrex", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061ICN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ICN7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A061ICN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ICN7" } ] } ] }, { "uniprot_ac": "A0A061IIX2", "gene_name": "Ddx58", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A061IIX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIX2" } ] }, { "ec_number": 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{ "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8C2MBY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBY6" } ] } ] }, { "uniprot_ac": "A0A8C2MCA5", "gene_name": "Ddx41", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCA5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MCA5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCA5" } ] } ] }, { "uniprot_ac": "A0A8C2MCS3", "gene_name": "Ddx47", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MCS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCS3" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MCS3", "database": "UniProtKB", "url": 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"ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.1.15", "activity": "", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] } ] }, { "uniprot_ac": "A0A8C2QLX9", "gene_name": "Ddx52", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QLX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLX9" } ] } ] }, { "uniprot_ac": "A0A8C2QM19", "gene_name": "Clpx", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A8C2QM19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QM19" } ] } ] }, { "uniprot_ac": "A0A8C2QNE7", "gene_name": "Eif4a3", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2QNE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNE7" } ] } ] }, { "uniprot_ac": "A0A9J7F1E5", "gene_name": "Hltf", "activity": [ { "ec_number": "2.3.2.27", "activity": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] }, { "ec_number": "2.3.2.27", "activity": "", "evidence": [ { "id": "A0A9J7F1E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1E5" } ] } ] }, { "uniprot_ac": "A0A9J7F876", "gene_name": "Ddx11", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F876", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F876" } ] } ] }, { "uniprot_ac": "A0A9J7F9W3", "gene_name": "Zgrf1", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] } ] }, { "uniprot_ac": "A0A9J7FCH5", "gene_name": "Mov10l1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] } ] }, { "uniprot_ac": "A0A9J7FI19", "gene_name": "Xrcc6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] } ] }, { "uniprot_ac": "A0A9J7FI42", "gene_name": "Fbh1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI42" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FJ37", "gene_name": "Mcm9", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FJ37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ37" } ] } ] }, { "uniprot_ac": "A0A9J7FPD0", "gene_name": "Dhx32", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FPD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPD0" } ] } ] }, { "uniprot_ac": "A0A9J7FPK3", "gene_name": "Twnk", "activity": [ { "ec_number": "5.6.2.3", "activity": "Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7FPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] } ] }, { "uniprot_ac": "A0A9J7FTT2", "gene_name": "Mcm5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] } ] }, { "uniprot_ac": "A0A9J7FU33", "gene_name": "Eif4a2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FU33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU33" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FU33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU33" } ] } ] }, { "uniprot_ac": "A0A9J7FUH6", "gene_name": "Polq", "activity": [ { "ec_number": "2.7.7.7", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.7", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.49", "activity": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "2.7.7.49", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7FUH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUH6" } ] } ] }, { "uniprot_ac": "A0A9J7FV95", "gene_name": "LOC100751095", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A9J7FV95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FV95" } ] } ] }, { "uniprot_ac": "A0A9J7FXI2", "gene_name": "Ddx10", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FXI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FXI2" } ] } ] }, { "uniprot_ac": "A0A9J7FYM8", "gene_name": "Ddx54", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FYM8", "database": 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{ "id": "A0A9J7G2T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2T1" } ] } ] }, { "uniprot_ac": "A0A9J7G412", "gene_name": "Helz2", "activity": [ { "ec_number": "3.1.13.1", "activity": "Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.1.13.1", "activity": "", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G412", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G412" } ] } ] }, { "uniprot_ac": "A0A9J7G5W9", "gene_name": "Spata5l1", "activity": [ { "ec_number": "3.6.4.10", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W9" } ] }, { "ec_number": "3.6.4.10", "activity": "", "evidence": [ { "id": "A0A9J7G5W9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5W9" } ] } ] }, { "uniprot_ac": "A0A9J7G659", "gene_name": "Rtel1", "activity": [ { "ec_number": "5.6.2.-", "activity": "", "evidence": [ { "id": "A0A9J7G659", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G659" } ] } ] }, { "uniprot_ac": "A0A9J7G6M1", "gene_name": "Mcm8", "activity": [ { "ec_number": "2.7.8.41", "activity": "a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H(+).", "evidence": [ { "id": "A0A9J7G6M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6M1" } ] }, { "ec_number": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283083" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDZ9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Smcr8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDZ9", "locus": {} } ], "crossref": [ { "id": "100772792", "url": "https://www.ncbi.nlm.nih.gov/gene/100772792", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037520", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037520", "database": "InterPro", "categories": [ "Protein Classification" ] 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Isoform 1 of Guanine nucleotide exchange protein SMCR8 isoform X2 OS=Cricetulus griseus OX=10029 GN=Smcr8 PE=3 SV=1 CANONICAL=A0A9J7GDZ9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 598, "start_aa": "Thr", "end_pos": 598, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr598", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GDZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDZ9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613631.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027240321.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027240321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240321" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE06", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE06" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tvp23a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE06", "locus": {} } ], "crossref": [ { "id": "A0A9J7GE06", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GE06", "database": "AlphaFoldDB", "categories": [] }, { "id": "100750344", "url": "https://www.ncbi.nlm.nih.gov/gene/100750344", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008564", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008564", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750344", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750344", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GE06", "url": "https://www.orthodb.org/?gene=A0A9J7GE06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13019", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13019", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13019:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13019:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027240321", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240321", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GE06", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GE06-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVHGWGLPSVLGVPQALVDDTEDVSLDFGNEEELAFRKAKIRHPLATFFHLFFRVSAIVTYVCCDWFSRSFVGCFVTVLLLLSFDFWSVKNVTGRLMVGLRWWNQIDEDGKSHWIFEARKVSPNHGAATEAEARIFWLGLIICPVIWTLFFFSTLFSLKLKWLALVITGISLQAANLYGYILCKMGGEGNISTVAASFLSQTVFQTASPGDFEKPRLEGRDIHQR", "length": 226, "header": "tr|A0A9J7GE06-1|A0A9J7GE06_CRIGR Isoform 1 of Golgi apparatus membrane protein TVP23 homolog OS=Cricetulus griseus OX=10029 GN=Tvp23a PE=3 SV=1 CANONICAL=A0A9J7GE06-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GE06-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE06/entry#A0A9J7GE06-1", "sequence": { "sequence": "MGVHGWGLPSVLGVPQALVDDTEDVSLDFGNEEELAFRKAKIRHPLATFFHLFFRVSAIVTYVCCDWFSRSFVGCFVTVLLLLSFDFWSVKNVTGRLMVGLRWWNQIDEDGKSHWIFEARKVSPNHGAATEAEARIFWLGLIICPVIWTLFFFSTLFSLKLKWLALVITGISLQAANLYGYILCKMGGEGNISTVAASFLSQTVFQTASPGDFEKPRLEGRDIHQR", "length": 226, "header": "tr|A0A9J7GE06-1|A0A9J7GE06_CRIGR Isoform 1 of Golgi apparatus membrane protein TVP23 homolog OS=Cricetulus griseus OX=10029 GN=Tvp23a PE=3 SV=1 CANONICAL=A0A9J7GE06-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE06", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE06" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE06", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE06" } ], "pmid": "" }, { "name": "protein secretion", "id": "GO:0009306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009306", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE06", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", 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automated computational analysis. This record is derived from a genomic sequence (NW_003615090.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007650069.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007650069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650069" } ] }, { "annotation": "Possible taste receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60#function" }, { "database": "UniProtKB", "id": "ARBA00053672", "url": "https://www.uniprot.org/uniprotkb/ARBA00053672#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100770188", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60", "locus": {} } ], "crossref": [ { "id": "A0A9J7GE60", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GE60", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15431", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15431", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770188", "url": "https://www.ncbi.nlm.nih.gov/gene/100770188", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770188", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770188", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GE60", "url": "https://www.orthodb.org/?gene=A0A9J7GE60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007650069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650069", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GE60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GE60-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWGLLVSSHLNRYGSGAGMRPQNSSSITELVLVGFSDHPQAEIPLFLLFSLVYLANCLGNTAVITLVALDPSLQTPMYFFLCHLAFLNGFFSTVVTPKMLFNFLASRKVISYPFCLAQTYLTLFLESTECFLLAVMAIDRYVAICYPLRYLLIISWTVCTALAVAVWVIGFCASVIPLYITILPLCGPYIVDYLFCELPVLLHMFCADTSLLESTMAVGGAGTVLFPFLLIVLSYLRILVAVLRIDSAEGRKKAFSTCASHLAVVTIYYGTGLIRYLRPKSLYSAEGDKLISVFYAVIGPAMNPFIYSLRNKEVQGAMRRVIERYQKCTRITF", "length": 333, "header": "tr|A0A9J7GE60-1|A0A9J7GE60_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100770188 PE=3 SV=1 CANONICAL=A0A9J7GE60-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GE60-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60/entry#A0A9J7GE60-1", "sequence": { "sequence": "MWGLLVSSHLNRYGSGAGMRPQNSSSITELVLVGFSDHPQAEIPLFLLFSLVYLANCLGNTAVITLVALDPSLQTPMYFFLCHLAFLNGFFSTVVTPKMLFNFLASRKVISYPFCLAQTYLTLFLESTECFLLAVMAIDRYVAICYPLRYLLIISWTVCTALAVAVWVIGFCASVIPLYITILPLCGPYIVDYLFCELPVLLHMFCADTSLLESTMAVGGAGTVLFPFLLIVLSYLRILVAVLRIDSAEGRKKAFSTCASHLAVVTIYYGTGLIRYLRPKSLYSAEGDKLISVFYAVIGPAMNPFIYSLRNKEVQGAMRRVIERYQKCTRITF", "length": 333, "header": "tr|A0A9J7GE60-1|A0A9J7GE60_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100770188 PE=3 SV=1 CANONICAL=A0A9J7GE60-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770188", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770188", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GE60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE60" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 307, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 23, "end_pos": 25 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GE61-1", "uniprot_ac": "A0A9J7GE61", "uniprot_id": "A0A9J7GE61_CRIGR", "mass": { "chemical_mass": 84468.0, "monoisotopic_mass": 84468.0 }, "refseq": { "ac": "XP_027283173", "name": "zinc finger protein 39 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283173" }, "gene_names": [ { "name": "LOC100762136", "type": "recommended", "evidence": [ { "id": "A0A9J7GE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61" } ] }, { "name": "LOC100762136", "type": "synonym", "evidence": [ { "id": "XP_027283173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283173" } ] } ], "protein_names": [ { "name": "Zinc finger protein 39 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7GE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 39 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027283173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283173" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283173" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100762136", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61", "locus": {} } ], "crossref": [ { "id": "A0A9J7GE61", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GE61", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762136", "url": "https://www.ncbi.nlm.nih.gov/gene/100762136", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762136", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762136", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GE61", "url": "https://www.orthodb.org/?gene=A0A9J7GE61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF246", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF246", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283173", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GE61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GE61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBQ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRNLQQDSVKNSMSQLPSQTLDIGKQKRSYKKSVTFINHWRWSQQCRARKHKEPVKGLVTFEDVCVDFTWEEWQDLDDAQRKLYRDVMLETYRSLESLGHCITKPEVIFKLEQGTGPWRVEDVPEQRRPDVQKVNGVDETSQDNQERHLWHLAITNSNTSTEKNVKLGKIFNVSSNHVSNLTVKNGSSSGMRSAALNVWQNMCPPSEPDNMQTGKELDGSLTSKPLIHAQHHGLYSRAPSTQQHFQCCRQEAACNTKALWTNKRFHIAHSPSKFAESEKASGEVAPNAQERTWEREETFECNICKKTFCSKFKLTKHKKIHKVQKYYKCSDCEKTFIKKSYHKKQVIHAGLRSYRCRQCEKFFHQKKQQNVCQRVPRGTKLYEVYQSEKSFNEKPNLRRYQRTRTGYKPYGCHMCGKSFYRKSHLNRHQRIHTGEKPYGCKECKKTFYHKSSLTIHQRTHTGEKPYECKKCRKTFYCKSDLNVHHRTHTGEKPYECDECRKTFYSKSHLIIHQKIHTGDKPYECEACQKTFNRKSNLTVHQKTHTGEKPYECNICGKTFHRKSHLSMHQKTHTGEKPYECKECGKAFYQKSSLSRHERNHTGNRPYACEECRKTFLHKSSLTVHQRSHTGYKPYSCEECRKTFYSKSHLTVHQRTHTGEKPYECPVCAKAFHQKSYLNRHQVTHESEKRFECEECRKTFYHKSSLTVHQKIHLRAGL", "length": 717, "header": "tr|A0A9J7GE61-1|A0A9J7GE61_CRIGR Isoform 1 of Zinc finger protein 39 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100762136 PE=3 SV=1 CANONICAL=A0A9J7GE61-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GE61-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61/entry#A0A9J7GE61-1", "sequence": { "sequence": "MRNLQQDSVKNSMSQLPSQTLDIGKQKRSYKKSVTFINHWRWSQQCRARKHKEPVKGLVTFEDVCVDFTWEEWQDLDDAQRKLYRDVMLETYRSLESLGHCITKPEVIFKLEQGTGPWRVEDVPEQRRPDVQKVNGVDETSQDNQERHLWHLAITNSNTSTEKNVKLGKIFNVSSNHVSNLTVKNGSSSGMRSAALNVWQNMCPPSEPDNMQTGKELDGSLTSKPLIHAQHHGLYSRAPSTQQHFQCCRQEAACNTKALWTNKRFHIAHSPSKFAESEKASGEVAPNAQERTWEREETFECNICKKTFCSKFKLTKHKKIHKVQKYYKCSDCEKTFIKKSYHKKQVIHAGLRSYRCRQCEKFFHQKKQQNVCQRVPRGTKLYEVYQSEKSFNEKPNLRRYQRTRTGYKPYGCHMCGKSFYRKSHLNRHQRIHTGEKPYGCKECKKTFYHKSSLTIHQRTHTGEKPYECKKCRKTFYCKSDLNVHHRTHTGEKPYECDECRKTFYSKSHLIIHQKIHTGDKPYECEACQKTFNRKSNLTVHQKTHTGEKPYECNICGKTFHRKSHLSMHQKTHTGEKPYECKECGKAFYQKSSLSRHERNHTGNRPYACEECRKTFLHKSSLTVHQRSHTGYKPYSCEECRKTFYSKSHLTVHQRTHTGEKPYECPVCAKAFHQKSYLNRHQVTHESEKRFECEECRKTFYHKSSLTVHQKIHLRAGL", "length": 717, "header": "tr|A0A9J7GE61-1|A0A9J7GE61_CRIGR Isoform 1 of Zinc finger protein 39 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100762136 PE=3 SV=1 CANONICAL=A0A9J7GE61-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61/entry#A0A9J7KBQ8-1", "sequence": { "sequence": "MSQLPSQTLDIGKQKRSYKKSVTFINHWRWSQQCRARKHKEPVKGLVTFEDVCVDFTWEEWQDLDDAQRKLYRDVMLETYRSLESLGHCITKPEVIFKLEQGTGPWRVEDVPEQRRPDVQKVNGVDETSQDNQERHLWHLAITNSNTSTEKNVKLGKIFNVSSNHVSNLTVKNGSSSGMRSAALNVWQNMCPPSEPDNMQTGKELDGSLTSKPLIHAQHHGLYSRAPSTQQHFQCCRQEAACNTKALWTNKRFHIAHSPSKFAESEKASGEVAPNAQERTWEREETFECNICKKTFCSKFKLTKHKKIHKVQKYYKCSDCEKTFIKKSYHKKQVIHAGLRSYRCRQCEKFFHQKKQQNVCQRVPRGTKLYEVYQSEKSFNEKPNLRRYQRTRTGYKPYGCHMCGKSFYRKSHLNRHQRIHTGEKPYGCKECKKTFYHKSSLTIHQRTHTGEKPYECKKCRKTFYCKSDLNVHHRTHTGEKPYECDECRKTFYSKSHLIIHQKIHTGDKPYECEACQKTFNRKSNLTVHQKTHTGEKPYECNICGKTFHRKSHLSMHQKTHTGEKPYECKECGKAFYQKSSLSRHERNHTGNRPYACEECRKTFLHKSSLTVHQRSHTGYKPYSCEECRKTFYSKSHLTVHQRTHTGEKPYECPVCAKAFHQKSYLNRHQVTHESEKRFECEECRKTFYHKSSLTVHQKIHLRAGL", "length": 705, "header": "tr|A0A9J7KBQ8-1|A0A9J7KBQ8_CRIGR Computationally mapped isoform of Zinc finger protein 39 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100762136 PE=3 SV=1 CANONICAL=A0A9J7GE61-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762136", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762136", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE61", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE61" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE61", "url": 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180, "end_pos": 182 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 599, "end_pos": 601 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"name": "Zinc finger protein 384", "type": "recommended", "evidence": [ { "id": "A0A9J7GE86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86/entry#names_and_taxonomy" } ] }, { "name": "Nuclear matrix transcription factor 4", "type": "synonym", "evidence": [ { "id": "A0A9J7GE86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 384 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027284076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284076" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027284076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284076" } ] }, { "annotation": "Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86#function" }, { "database": "UniProtKB", "id": "ARBA00058819", "url": "https://www.uniprot.org/uniprotkb/ARBA00058819#function" }, { "database": "UniProtKB", "id": "A0A9J7GEL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEL7#function" }, { "database": "UniProtKB", "id": "A0A9J7GFE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFE1#function" }, { "database": "UniProtKB", "id": "A0A9J7GH47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GH47#function" }, { "database": "UniProtKB", "id": "A0A9J7GH51", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GH51#function" }, { "database": "UniProtKB", "id": "A0A9J7GJT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJT5#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf384", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86", "locus": {} } ], "crossref": [ { "id": "100755622", "url": "https://www.ncbi.nlm.nih.gov/gene/100755622", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755622", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755622", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GE86", "url": "https://www.orthodb.org/?gene=A0A9J7GE86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF401", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF401", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF97", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF97", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027284076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284076", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GE86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEL7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GFE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GFE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GH47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GH47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GH47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GH47-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GH51", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GH51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GH51-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GH51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJT5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQNITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPGLVITSPSGSLVTTASSAQTFPISAPMIVSALPPGSQALQVVPDLSKKVAPTLTEEGGGGGGGGGSVAPPKPPRGRKKKRVLESGLPEMNDPYVLAPDDDDHQKDGKTYRSEGNCGTGNGQSLGLMDSVPGSTTNLLCDPGCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNFCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVSQASQQQQQQQQQPPPPPQPPHFQSPGAAPQGGGGGDSNPNPPPQCSFDLTPYKTAEHHKDICLTVTTSTIQVEHLASS", "length": 614, "header": "tr|A0A9J7GE86-1|A0A9J7GE86_CRIGR Isoform 1 of Zinc finger protein 384 OS=Cricetulus griseus OX=10029 GN=Znf384 PE=3 SV=1 CANONICAL=A0A9J7GE86-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GE86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86/entry#A0A9J7GE86-1", "sequence": { "sequence": "MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQNITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPGLVITSPSGSLVTTASSAQTFPISAPMIVSALPPGSQALQVVPDLSKKVAPTLTEEGGGGGGGGGSVAPPKPPRGRKKKRVLESGLPEMNDPYVLAPDDDDHQKDGKTYRSEGNCGTGNGQSLGLMDSVPGSTTNLLCDPGCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNFCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVSQASQQQQQQQQQPPPPPQPPHFQSPGAAPQGGGGGDSNPNPPPQCSFDLTPYKTAEHHKDICLTVTTSTIQVEHLASS", "length": 614, "header": "tr|A0A9J7GE86-1|A0A9J7GE86_CRIGR Isoform 1 of Zinc finger protein 384 OS=Cricetulus griseus OX=10029 GN=Znf384 PE=3 SV=1 CANONICAL=A0A9J7GE86-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86/entry#A0A9J7GEL7-1", "sequence": { "sequence": "MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQNITVVPVPSTGLMTAGPGLVITSPSGSLVTTASSAQTFPISAPMIVSALPPGSQALQVVPDLSKKVAPTLTEEGGGGGGGGGSVAPPKPPRGRKKKRVLESGLPEMNDPYVLAPDDDDHQKDGKTYRCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNFCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVSQASQQQQQQQQQPPPPPQPPHFQSPGAAPQGGGGGDSNPNPPPQCSFDLTPYKTAEHHKDICLTVTTSTIQVEHLASS", "length": 567, "header": "tr|A0A9J7GEL7-1|A0A9J7GEL7_CRIGR Computationally mapped isoform of Zinc finger protein 384 OS=Cricetulus griseus OX=10029 GN=Znf384 PE=3 SV=1 CANONICAL=A0A9J7GE86-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GFE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86/entry#A0A9J7GFE1-1", "sequence": { "sequence": "MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQNITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPGLVITSPSGSLVTTASSAQTFPISAPMIVSALPPGSQALQVVPDLSKKVAPTLTEEGGGGGGGGGSVAPPKPPRGRKKKRVLESGLPEMNDPYVLAPDDDDHQKDGKTYRCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNFCEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVSQASQQQQQQQQQPPPPPQPPHFQSPGAAPQGGGGGDSNPNPPPQCSFDLTPYKTAEHHKDICLTVTTSTIQVEHLASS", "length": 522, "header": "tr|A0A9J7GFE1-1|A0A9J7GFE1_CRIGR Computationally mapped isoform of Zinc finger protein 384 OS=Cricetulus griseus OX=10029 GN=Znf384 PE=3 SV=1 CANONICAL=A0A9J7GE86-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GH47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86/entry#A0A9J7GH47-1", "sequence": { "sequence": "MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQNITVVPVPSTGLMTAGPGLVITSPSGSLVTTASSAQTFPISAPMIVSALPPGSQALQVVPDLSKKVAPTLTEEGGGGGGGGGSVAPPKPPRGRKKKRVLESGLPEMNDPYVLAPDDDDHQKDGKTYRSEGNCGTGNGQSLGLMDSVPGSTTNLLCDPGCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNFCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVSQASQQQQQQQQQPPPPPQPPHFQSPGAAPQGGGGGDSNPNPPPQCSFDLTPYKTAEHHKDICLTVTTSTIQVEHLASS", "length": 598, "header": "tr|A0A9J7GH47-1|A0A9J7GH47_CRIGR Computationally mapped isoform of Zinc finger protein 384 OS=Cricetulus griseus OX=10029 GN=Znf384 PE=3 SV=1 CANONICAL=A0A9J7GE86-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GH51-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86/entry#A0A9J7GH51-1", "sequence": { "sequence": "MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQNITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPGLVITSPSGSLVTTASSAQTFPISAPMIVSALPPGSQALQVVPDLSKKVAPTLTEEGGGGGGGGGSVAPPKPPRGRKKKRVLESGLPEMNDPYVLAPDDDDHQKDGKTYRCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNFCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVSQASQQQQQQQQQPPPPPQPPHFQSPGAAPQGGGGGDSNPNPPPQCSFDLTPYKTAEHHKDICLTVTTSTIQVEHLASS", "length": 583, "header": "tr|A0A9J7GH51-1|A0A9J7GH51_CRIGR Computationally mapped isoform of Zinc finger protein 384 OS=Cricetulus griseus OX=10029 GN=Znf384 PE=3 SV=1 CANONICAL=A0A9J7GE86-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86/entry#A0A9J7GJT5-1", "sequence": { "sequence": "MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGLAPPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQNITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPGLVITSPSGSLVTTASSAQTFPISAPMIVSALPPGSQALQVVPDLSKKVAPTLTEEGGGGGGGGGSVAPPKPPRGRKKKRVLESGLPEMNDPYVLAPDDDDHQKDGKTYRSEGNCGTGNGQSLGLMDSVPGSTTNLLCDPGCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNFCEKSFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVSQASQQQQQQQQQPPPPPQPPHFQSPGAAPQGGGGGDSNPNPPPQCSFDLTPYKTAEHHKDICLTVTTSTIQVEHLASS", "length": 553, "header": "tr|A0A9J7GJT5-1|A0A9J7GJT5_CRIGR Computationally mapped isoform of Zinc finger protein 384 OS=Cricetulus griseus OX=10029 GN=Znf384 PE=3 SV=1 CANONICAL=A0A9J7GE86-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755622", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755622", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" }, { "name": "transcription regulator complex", "id": "GO:0005667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005667", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" }, { "name": "PcG protein complex", "id": "GO:0031519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031519", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" }, { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" }, { "name": "sequence-specific double-stranded DNA binding", "id": "GO:1990837", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990837", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GE86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GE86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE86" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 259, "end_pos": 286, "start_aa": "Pro", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GEB3-1", "uniprot_ac": "A0A9J7GEB3", "uniprot_id": "A0A9J7GEB3_CRIGR", "mass": { "chemical_mass": 40178.0, "monoisotopic_mass": 40178.0 }, "refseq": { "ac": "XP_027283830", "name": "protein HEXIM1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283830" }, "gene_names": [ { "name": "Hexim1", "type": "recommended", "evidence": [ { "id": "A0A9J7GEB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEB3" } ] }, { "name": "Hexim1", "type": "synonym", "evidence": [ { "id": "XP_027283830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283830" } ] } ], "protein_names": [ { "name": "Protein HEXIM1", "type": "synonym", "evidence": [ { "id": "A0A9J7GEB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEB3/entry#names_and_taxonomy" } ] }, { "name": "protein HEXIM1", "type": "synonym", "evidence": [ { "id": "XP_027283830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283830" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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"length": 2594, "header": "tr|A0A9J7GEB4-1|A0A9J7GEB4_CRIGR Isoform 1 of von Willebrand factor OS=Cricetulus griseus OX=10029 GN=Vwf PE=4 SV=1 CANONICAL=A0A9J7GEB4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1028, "start_aa": "Thr", "end_pos": 1028, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1028", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1463, "start_aa": "Thr", "end_pos": 1463, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1463", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEB4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEB4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750531", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750531", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEB4" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEB4" } ], "pmid": "" }, { "name": "Weibel-Palade body", "id": "GO:0033093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033093", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "platelet activation", "id": "GO:0030168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030168", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEB4" } ], "pmid": "" }, { "name": "cell-substrate adhesion", "id": "GO:0031589", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031589", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEB4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1011, "end_pos": 1013, "annotation": "n_glycosylation_sequon" }, { 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"table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GEC3-1", "uniprot_ac": "A0A9J7GEC3", "uniprot_id": "A0A9J7GEC3_CRIGR", "mass": { "chemical_mass": 43812.0, "monoisotopic_mass": 43812.0 }, "refseq": { "ac": "XP_003497225", "name": "sex hormone-binding globulin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497225" }, "gene_names": [ { "name": "Shbg", "type": "recommended", "evidence": [ { "id": "A0A9J7GEC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3" } ] }, { "name": "Shbg", "type": "synonym", "evidence": [ { "id": "XP_003497225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497225" } ] } ], "protein_names": [ { "name": "Sex hormone-binding globulin", "type": "recommended", "evidence": [ { "id": "A0A9J7GEC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3/entry#names_and_taxonomy" } ] }, { "name": "Sex steroid-binding protein", "type": "synonym", "evidence": [ { "id": "A0A9J7GEC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3/entry#names_and_taxonomy" } ] }, { "name": "Testis-specific androgen-binding protein", "type": "synonym", "evidence": [ { "id": "A0A9J7GEC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3/entry#names_and_taxonomy" } ] }, { "name": "sex hormone-binding globulin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003497225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497225" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613643.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497225" } ] }, { "annotation": "Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. 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"MENRDSVVSLLLLLLLLLLPLHTHQGHIAPTQSAQNSPARYLSNGPGQEPVAVITIDRTKISKPYSSFEFRTLDPEGVIFYGDTNTKDDWFMLGLRDGQLETQLHNFWARLTVGFGPQLNDGRWHQVELKMYGDSLQLRVDGKELLCLRQVSGSLADNSQPSMRIALGGLLLPTSSLRFPLVPALDGCIRRDIWLGHQAPLSTSAPSNLGNCDVDLQPGLFFPPGTHAEFSLQDIPQPHTDPWSFSLELGFKLVDGSGRLLALGTRTNSSWLTLHLQDQKVVLSSGVEPKLVLPLEMELPLQLKLDIFKVILSQGSKMEVLAVSVSRLVALQRLWSCPQGLLSLGALAGDDSSASFCLSDLWVQGQRLDIDQALNRSQNIWTHSCPQSPNNVSHTSY", "length": 397, "header": "tr|A0A9J7GEC3-1|A0A9J7GEC3_CRIGR Isoform 1 of Sex hormone-binding globulin OS=Cricetulus griseus OX=10029 GN=Shbg PE=4 SV=1 CANONICAL=A0A9J7GEC3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3/entry#A0A9J7H6S2-1", "sequence": { "sequence": "MENRDSVVSLLLLLLLLLLPLHTHQGHIAPTQSAQNSPARYLSNGPGQEPVAVITIDRTKISKPYSSFEFRTLDPEGVIFYGDTNTKDDWFMLGLRDGQLETQLHNFWARLTVGFGPQLNDGRWHQVELKMYGDSLQLRVDGKELLCLRQVSGSLADNSQPSMRIALGGLLLPTSSLRFPLVPALDGCIRRDIWLGHQAPLSTSAPSNLGNCDVDLQPGLFFPPGTHAEFSLQGDDSSASFCLSDLWVQGQRLDIDQALNRSQNIWTHSCPQSPNNVSHTSY", "length": 282, "header": "tr|A0A9J7H6S2-1|A0A9J7H6S2_CRIGR Computationally mapped isoform of Sex hormone-binding globulin OS=Cricetulus griseus OX=10029 GN=Shbg PE=4 SV=1 CANONICAL=A0A9J7GEC3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KC52-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3/entry#A0A9J7KC52-1", "sequence": { "sequence": "MENRDSVVSLLLLLLLLLLPLHTHQGHIAPTQSAQNSPARYLSNGPGQEPVAVITIDRTKISKPYSSFEFRTLDPEGVIFYGDTNTKDDWFMLGLRDGQLETQLHNFWARLTVGFGPQLNDGRWHQVELKMYGDSLQLRVDGKELLCLRQVSGSLADNSQPSMRIALGGLLLPTSSLRFPAPLSTSAPSNLGNCDVDLQPGLFFPPGTHAEFSLQDIPQPHTDPWSFSLELGFKLVDGSGRLLALGTRTNSSWLTLHLQDQKVVLSSGVEPKLVLPLEMELPLQLKLDIFKVILSQGSKMEVLAVSVSRLVALQRLWSCPQGLLSLGALAGDDSSASFCLSDLWVQGQRLDIDQALNRSQNIWTHSCPQSPNNVSHTSY", "length": 379, "header": "tr|A0A9J7KC52-1|A0A9J7KC52_CRIGR Computationally mapped isoform of Sex hormone-binding globulin OS=Cricetulus griseus OX=10029 GN=Shbg PE=4 SV=1 CANONICAL=A0A9J7GEC3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 31, "start_aa": "Thr", "end_pos": 31, "end_aa": "Thr", 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762290", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762290", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "steroid binding", "id": "GO:0005496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005496", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GEC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEC3" }, { "id": "PS50025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin G", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 212, "start_aa": "Arg", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 31 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 391, "end_pos": 393 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"MDPPAGAARAXALPALLLLLLPPPPLLLLPPPPASARLAXATEPPGGPPGHGAERILAVPVRTDAQGRLVSHVVSSETTGAGVRARRAAPVQTSGLPGGNDVQDPGGRLFYNLTVFGRDLHLRLRPNARLVAPGATVEWQGETGDTRVEPLLGTCLYVGDVAGLAKASSVALSNCDGLAGLIRMEEEEFFIEPLERGQTDQEAEQGRVHVVYRRPPTPKPPPLAGPQALDTGASRGRLESLSRALGVLEEHINSSRRRVRRHAADDDYNIEVLLGVDDSVVQFHGKEHVQKYLLTLMNIVNEIYHDESLGAHINVVLVRIILLNHEKSMNLIEIGNPSQSLENVCRWAYLQQKPDTDHDEYHDHAIFLTRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDEVRLGSIMAPLVQAAFHRFHWSRCSQQELGRYLHSYDCLRDDPFAHDWPALPQLPGLHYSMNEQCRFDFGLGYMMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTMCAPGKHCFKGHCIWLTPDILKRDGNWGAWTPFGSCSRTCGTGVKFRTRQCDNPHPANGGRTCSGLAYDFQLCNPQDCPNSLADFREEQCRQWDLYFEHGDGQHHWLPHEHRDAKERCHLYCESKETGEVVSMKRMVHDGTRCSYKDAFSLCVRGDCKKVGCDGVIGSRKQEDKCGVCGGDNTHCKVVKGTFTRSPRKQEYIKMFEIPAGARHLLIQEADTTSHYLSVKNLETGKFILNEENHLDPNSRTFIAMGVEWEYRNEDERETLQTIGPLHGTITVLVIPEGDSRISLTYKYMIHEDSLNVDDNNVLEDDSVRHEWALKKWSPCSKPCGGGSQFTKYGCRRRLDSKMVHRAFCSALAKPKAIRRACNPQECSQPVWVAGEWEPCSQSCGRTGMQVRSVRCIQPLHNNTTRSVHTKHCNDHRPESRRACNRELCPGRWRAGSWSQCSVTCGNGTQERPVLCRTADDNFGVCREERPETARICRLAPCPRNISDPSKKSYVVQWLSRPDPDSPIRKISSKGQCQGDKSMFCRMEVLSRYCSIPSYNKLCCKSCNPAHNLSNTEDTGVESPPGKHNDIDVFMPTLPGPTIATQVQPSAGPPLEIPLNVSSVNATEDHPETNAVDVPYQIHGVDEEVQSPNLIPRRPSLYVKTRNQRIQELINAVQKKEKARKF", "length": 1214, "header": "tr|A0A9J7GEH7-1|A0A9J7GEH7_CRIGR Isoform 1 of LOW QUALITY PROTEIN: A disintegrin and metalloproteinase with thrombospondin motifs 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100769264 PE=4 SV=1 CANONICAL=A0A9J7GEH7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1130, "start_aa": "Thr", "end_pos": 1130, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1130", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769264", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH7" } ], "pmid": "" }, { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEH7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEH7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282044" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Myh13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI6", "locus": {} } ], "crossref": [ { "id": "cd14923", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14923", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768976", "url": "https://www.ncbi.nlm.nih.gov/gene/100768976", "database": "GeneID", "categories": [ "Genome 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042702", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042702", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768976", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768976", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GEI6", "url": "https://www.orthodb.org/?gene=A0A9J7GEI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45615", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45615", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45615:SF64", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45615:SF64", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282044", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282044", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GEI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1939, "header": "tr|A0A9J7GEI6-1|A0A9J7GEI6_CRIGR Isoform 1 of Myosin-13 OS=Cricetulus griseus OX=10029 GN=Myh13 PE=3 SV=1 CANONICAL=A0A9J7GEI6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768976", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768976", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI6" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEI6", 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This record is derived from a genomic sequence (NW_003614943.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510752" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEJ5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Figla", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEJ5", "locus": {} } ], "crossref": [ { "id": "A0A9J7GEJ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GEJ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11422", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11422", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755024", "url": "https://www.ncbi.nlm.nih.gov/gene/100755024", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755024", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755024", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDKQNYS", "url": "https://omabrowser.org/oma/group/PDKQNYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GEJ5", "url": "https://www.orthodb.org/?gene=A0A9J7GEJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23349:SF57", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23349:SF57", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510752", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GEJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTTSPASPEPFLAVPQAEVLQELLQAQLGPLPRLAAICRLKRLPSGSYSTMDDLHLVLERRRVANAKERERIKNLNRGFAKLKALVPFLPQSRKPSKVDILKGATEYIRVLGCVLEGAKASEKQGPEEQTHSSRSSDPHVPSTREFLGNATQATSHASGLKKEEGPWAYGGHSEPLYTCQQSTAPVTRSYFIHQESDERFLLK", "length": 204, "header": "tr|A0A9J7GEJ5-1|A0A9J7GEJ5_CRIGR Isoform 1 of Factor in the germline alpha OS=Cricetulus griseus OX=10029 GN=Figla PE=4 SV=1 CANONICAL=A0A9J7GEJ5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GEJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEJ5/entry#A0A9J7GEJ5-1", "sequence": { "sequence": "MDTTSPASPEPFLAVPQAEVLQELLQAQLGPLPRLAAICRLKRLPSGSYSTMDDLHLVLERRRVANAKERERIKNLNRGFAKLKALVPFLPQSRKPSKVDILKGATEYIRVLGCVLEGAKASEKQGPEEQTHSSRSSDPHVPSTREFLGNATQATSHASGLKKEEGPWAYGGHSEPLYTCQQSTAPVTRSYFIHQESDERFLLK", "length": 204, "header": "tr|A0A9J7GEJ5-1|A0A9J7GEJ5_CRIGR Isoform 1 of Factor in the germline alpha OS=Cricetulus griseus OX=10029 GN=Figla PE=4 SV=1 CANONICAL=A0A9J7GEJ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEJ5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEJ5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755024", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755024", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AD65-1", "protein_name": "Factor in the germline alpha", "gene_name": "Figla", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTSSPASPEPFLATPQAEVLEELLQTQLGPLPRLAAICRLKRLPSGGYSTTDDLHLVLERRRVANAKERERIKNLNRGFAKLKALVPFLPQSRKPSKVDILKGATEYIRILGCVLEGAKASEKQGPEEQQVHSSRPSDPHVSSTRELLGNATQPTGCASGLKKEEEGPWAYGGHSELYSYHQSAVPETRSYFIH", "length": 195 }, "evidence": [ { "id": "A0A9J7GEJ5", "url": "https://omabrowser.org/oma/group/A0A9J7GEJ5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O55208-1", "protein_name": "Factor in the germline alpha", "gene_name": "Figla", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTAPASPEPFLVTPQAEVLEELIQAQMGPLPRLAAICRLKRLPSGGYSTTDDLHLVLERRRVANAKERERIKNLNRGFAKLKALVPFLPQSRKPSKVDILKGATEYIQILGCVLEEAKVSEKQSPEEQTHSGRPSDPHVSSTRELLGNATQPTSCASGLKKEEEGPWAYAGHSEPLYSYHQSTVPETRSYFTH", "length": 194 }, "evidence": [ { "id": "A0A9J7GEJ5", "url": "https://omabrowser.org/oma/group/A0A9J7GEJ5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6QHK4-1", "protein_name": "Factor in the germline alpha", "gene_name": "FIGLA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPAPGVLDPRAAPPALLGTPQAEVLEDVLREQFGPLPQLAAVCRLKRLPSGGYSSTENLQLVLERRRVANAKERERIKNLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLLEGAKDSKKQDPDEQSYSNNSSESHTSSARQLSRNITQHISCAFGLKNEEEGPWADGGSGEPAHACRHSVMSTTEIISPTRSLDRFPEVELLSHRLPQV", "length": 219 }, "evidence": [ { "id": "A0A9J7GEJ5", "url": "https://omabrowser.org/oma/group/A0A9J7GEJ5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEJ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEJ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEJ5", "url": 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[], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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{ "id": "XP_016825182", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016825182" } ] } ], "protein_names": [ { "name": "Vascular endothelial zinc finger 1 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7GEK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3/entry#names_and_taxonomy" } ] }, { "name": "vascular endothelial zinc finger 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016825182", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016825182" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 49 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613683.1) and transcript sequence (JI866096.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016825182", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016825182" } ] }, { "annotation": "Transcriptional regulator. Acts as a transcriptional activator that binds to purine-rich GAGA sites found in the promoter of many genes including insulin I and II and islet amyloid polypeptide.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3#function" }, { "database": "UniProtKB", "id": "ARBA00058862", "url": "https://www.uniprot.org/uniprotkb/ARBA00058862#function" }, { "database": "UniProtKB", "id": "A0A8C2M9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9Q2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Vezf1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3", "locus": {} } ], "crossref": [ { "id": "A0A9J7GEK3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GEK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100766279", "url": "https://www.ncbi.nlm.nih.gov/gene/100766279", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766279", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766279", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M9Q2", "url": "https://www.orthodb.org/?gene=A0A8C2M9Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GEK3", "url": "https://www.orthodb.org/?gene=A0A9J7GEK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14196:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14196:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016825182", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016825182", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M9Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEANWTAFLFQAHEASHHQQQAAQNSLLPLLSSAVEPPDQKPLLPIPITQKPQAAPETLKDAIGIKKEKPKTSFVCTYCSKAFRDSYHLRRHQSCHTGIKLVSRAKKTPTTVVPLISTIAGDSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTAMPVPQAVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKHVHSTERPFKCQFSSLMQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFNITSSVTSGTMSNPVTVAAAMSMRSPVNVSSAVNITSPMNIGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAAPLNIAMRPVESMPFLPQALPTSPPW", "length": 523, "header": "tr|A0A9J7GEK3-1|A0A9J7GEK3_CRIGR Isoform 1 of Vascular endothelial zinc finger 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Vezf1 PE=4 SV=1 CANONICAL=A0A9J7GEK3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M9Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3/entry#A0A8C2M9Q2-1", "sequence": { "sequence": "MEANWTAFLFQAHEASHHQQQAAQNSLLPLLSSAVEPPDQKPLLPIPITQKPQAAPETLKDAIGIKKEKPKTSFVCTYCSKAFRDSYHLRRHQSCHTGIKLVSRAKKTPTTVVPLISTIAGDSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTAMPVPQAVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFNITSSVTSGTMSNPVTVAAAMSMRSPVNVSSAVNITSPMNIGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAAPLNIAMRPVESMPFLPQALPTSPPW", "length": 517, "header": "tr|A0A8C2M9Q2-1|A0A8C2M9Q2_CRIGR Computationally mapped isoform of Vascular endothelial zinc finger 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Vezf1 PE=4 SV=1 CANONICAL=A0A9J7GEK3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3/entry#A0A9J7GEK3-1", "sequence": { "sequence": "MEANWTAFLFQAHEASHHQQQAAQNSLLPLLSSAVEPPDQKPLLPIPITQKPQAAPETLKDAIGIKKEKPKTSFVCTYCSKAFRDSYHLRRHQSCHTGIKLVSRAKKTPTTVVPLISTIAGDSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTAMPVPQAVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKHVHSTERPFKCQFSSLMQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFNITSSVTSGTMSNPVTVAAAMSMRSPVNVSSAVNITSPMNIGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAAPLNIAMRPVESMPFLPQALPTSPPW", "length": 523, "header": "tr|A0A9J7GEK3-1|A0A9J7GEK3_CRIGR Isoform 1 of Vascular endothelial zinc finger 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Vezf1 PE=4 SV=1 CANONICAL=A0A9J7GEK3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766279", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766279", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "pmid": "" }, { "name": "positive regulation of endothelial cell differentiation", "id": "GO:0045603", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045603", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GEK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 101, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 404, "end_pos": 406 }, { "start_pos": 431, "end_pos": 433 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GEK4-1", "uniprot_ac": "A0A9J7GEK4", "uniprot_id": "A0A9J7GEK4_CRIGR", "mass": { "chemical_mass": 38762.0, "monoisotopic_mass": 38762.0 }, "refseq": { "ac": "XP_007646785", "name": "LOW QUALITY PROTEIN: retroviral-like aspartic protease 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646785" }, "gene_names": [ { "name": "Asprv1", "type": "recommended", "evidence": [ { "id": "A0A9J7GEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4" } ] }, { "name": "Asprv1", "type": "synonym", "evidence": [ { "id": "XP_007646785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646785" } ] } ], "protein_names": [ { "name": "Retroviral-like aspartic protease 1", "type": "recommended", "evidence": [ { "id": "A0A9J7GEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: retroviral-like aspartic protease 1", "type": "synonym", "evidence": [ { "id": "XP_007646785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646785" } ] }, { "name": "Skin-specific retroviral-like aspartic protease", "type": "synonym", "evidence": [ { "id": "A0A9J7GEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4/entry#names_and_taxonomy" } ] }, { "name": "TPA-inducible aspartic proteinase-like protein", "type": "synonym", "evidence": [ { "id": "A0A9J7GEK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614461.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007646785.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007646785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646785" } ] }, { "annotation": "Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4#function" }, { "database": "UniProtKB", "id": "ARBA00053118", "url": "https://www.uniprot.org/uniprotkb/ARBA00053118#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Asprv1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4", "locus": {} } ], "crossref": [ { "id": "A0A9J7GEK4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GEK4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00303", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00303", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773346", "url": "https://www.ncbi.nlm.nih.gov/gene/100773346", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033539", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033539", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773346", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773346", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GEK4", "url": "https://www.orthodb.org/?gene=A0A9J7GEK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37006:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37006:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13975", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13975", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007646785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646785", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GEK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAGGRDQGVELLEQRRMRSPGGPGWASKRPCAESRTQTACLCVQQPARHPVPAPFNLPRLGKYTALSTEALLSSVIAPTLLCAFLYLACAAAELPETTRGMATSRARSQEGHREHAFIPEPFNGANVAPSLWLHRFEVIDDLNHWDHATKLRFLKESLRGDALDVYNGLNSQAQGDYSTVKEALLRAFGGSGTAHSQKPREILFANSMGKGYYLKGKIGPVPVRFLVDSGAQVSVVHPSLWEEVTDGDLDTLRPFENVVKVANGAEMKILGVWDTEVTLGKLKLSAQFLVANASAEEAIIGTDVLQDHNAVLDFQHRTCTLKGKKFRMLPVGGPLEEEFDLELIEEEPLEGSH", "length": 354, "header": "tr|A0A9J7GEK4-1|A0A9J7GEK4_CRIGR Isoform 1 of Retroviral-like aspartic protease 1 OS=Cricetulus griseus OX=10029 GN=Asprv1 PE=4 SV=1 CANONICAL=A0A9J7GEK4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GEK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4/entry#A0A9J7GEK4-1", "sequence": { "sequence": "MLAGGRDQGVELLEQRRMRSPGGPGWASKRPCAESRTQTACLCVQQPARHPVPAPFNLPRLGKYTALSTEALLSSVIAPTLLCAFLYLACAAAELPETTRGMATSRARSQEGHREHAFIPEPFNGANVAPSLWLHRFEVIDDLNHWDHATKLRFLKESLRGDALDVYNGLNSQAQGDYSTVKEALLRAFGGSGTAHSQKPREILFANSMGKGYYLKGKIGPVPVRFLVDSGAQVSVVHPSLWEEVTDGDLDTLRPFENVVKVANGAEMKILGVWDTEVTLGKLKLSAQFLVANASAEEAIIGTDVLQDHNAVLDFQHRTCTLKGKKFRMLPVGGPLEEEFDLELIEEEPLEGSH", "length": 354, "header": "tr|A0A9J7GEK4-1|A0A9J7GEK4_CRIGR Isoform 1 of Retroviral-like aspartic protease 1 OS=Cricetulus griseus OX=10029 GN=Asprv1 PE=4 SV=1 CANONICAL=A0A9J7GEK4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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[ { "database": "UniProtKB", "id": "A0A9J7GEK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 293, "end_pos": 295 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GEK7-1", "uniprot_ac": "A0A9J7GEK7", "uniprot_id": "A0A9J7GEK7_CRIGR", "mass": { "chemical_mass": 46466.0, "monoisotopic_mass": 46466.0 }, "refseq": { "ac": "XP_027283476", "name": "immunity-related GTPase family M protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283476" }, "gene_names": [ { "name": "LOC100768530", "type": "recommended", "evidence": [ { "id": "A0A9J7GEK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK7" } ] }, { "name": "LOC100768530", "type": "synonym", "evidence": [ { "id": "XP_027283476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283476" } ] } ], "protein_names": [ { "name": "Immunity-related GTPase family M protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7GEK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK7/entry#names_and_taxonomy" } ] }, { "name": "immunity-related GTPase family M protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027283476", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283476" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283476" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100768530", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK7", "locus": {} } ], "crossref": [ { "id": "A0A9J7GEK7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GEK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768530", "url": "https://www.ncbi.nlm.nih.gov/gene/100768530", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768530", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768530", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GEK7", "url": "https://www.orthodb.org/?gene=A0A9J7GEK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32341", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32341", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32341:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32341:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283476", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283476", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GEK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPSHKSWEAEPLLPNMAETSYAPLNSSFAFATSYQTAGGILPEVSRTVERALKEGKMLDVVYGVKETVAALSQTPVNITVTGDSGNGMSSFINALRIIGHEEDASAPTGVVRTTQTRAKYSSSQFPNVVLWDLPGLGATAQTVDNYGEEMKFNMYDLFIIIASEQFSLNHVNLAKVIQRMGKRFYIVWTKLDRDLSTCVLSEVRLLQNIRENIQENLQKEGVNIPPIFLVSNLDPLLHDFPKLRDMLHKDLSNIRCCVPLNTLSGTCEKIIDEKVAFLKERVGNGGSEHSVCIRDDDDMEECVKTYRLKFGIDDQSLQQVAQSMGTVVQEYKANLKSQNMHTLRRGDWRLRLMTCILVSVFFSILKYLPCLRCCVAWFRRKKHRRVLQLVAQDTKIILKKIGKDSISPPLT", "length": 412, "header": "tr|A0A9J7GEK7-1|A0A9J7GEK7_CRIGR Isoform 1 of Immunity-related GTPase family M protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100768530 PE=3 SV=1 CANONICAL=A0A9J7GEK7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GEK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK7/entry#A0A9J7GEK7-1", "sequence": { "sequence": "MKPSHKSWEAEPLLPNMAETSYAPLNSSFAFATSYQTAGGILPEVSRTVERALKEGKMLDVVYGVKETVAALSQTPVNITVTGDSGNGMSSFINALRIIGHEEDASAPTGVVRTTQTRAKYSSSQFPNVVLWDLPGLGATAQTVDNYGEEMKFNMYDLFIIIASEQFSLNHVNLAKVIQRMGKRFYIVWTKLDRDLSTCVLSEVRLLQNIRENIQENLQKEGVNIPPIFLVSNLDPLLHDFPKLRDMLHKDLSNIRCCVPLNTLSGTCEKIIDEKVAFLKERVGNGGSEHSVCIRDDDDMEECVKTYRLKFGIDDQSLQQVAQSMGTVVQEYKANLKSQNMHTLRRGDWRLRLMTCILVSVFFSILKYLPCLRCCVAWFRRKKHRRVLQLVAQDTKIILKKIGKDSISPPLT", "length": 412, "header": "tr|A0A9J7GEK7-1|A0A9J7GEK7_CRIGR Isoform 1 of Immunity-related GTPase family M protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100768530 PE=3 SV=1 CANONICAL=A0A9J7GEK7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JW25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEK7/entry#A0A9J7JW25-1", "sequence": { "sequence": "MAETSYAPLNSSFAFATSYQTAGGILPEVSRTVERALKEGKMLDVVYGVKETVAALSQTPVNITVTGDSGNGMSSFINALRIIGHEEDASAPTGVVRTTQTRAKYSSSQFPNVVLWDLPGLGATAQTVDNYGEEMKFNMYDLFIIIASEQFSLNHVNLAKVIQRMGKRFYIVWTKLDRDLSTCVLSEVRLLQNIRENIQENLQKEGVNIPPIFLVSNLDPLLHDFPKLRDMLHKDLSNIRCCVPLNTLSGTCEKIIDEKVAFLKERVGNGGSEHSVCIRDDDDMEECVKTYRLKFGIDDQSLQQVAQSMGTVVQEYKANLKSQNMHTLRRGDWRLRLMTCILVSVFFSILKYLPCLRCCVAWFRRKKHRRVLQLVAQDTKIILKKIGKDSISPPLT", "length": 396, "header": "tr|A0A9J7JW25-1|A0A9J7JW25_CRIGR Computationally mapped isoform of Immunity-related GTPase family M protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100768530 PE=3 SV=1 CANONICAL=A0A9J7GEK7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283618" } ] }, { "annotation": "Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring leukocyte cell-cell adhesion, by providing a calibrated system to namely adjust T-cell killing to the antigen stimulation strength. Also functions as a ligand receptor of the signaling receptor ITGAM:ITGB2/MAC-1 ensuring adhesion between stimulated neutrophils and stimulated endothelial cells. During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. 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"IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751267", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751267", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GER0", "url": "https://www.orthodb.org/?gene=A0A9J7GER0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13771:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13771:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21146", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21146", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283618", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GER0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GER0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKMLLLGIWTLLALIPCPGTTEELFEVSVWPNPALVKFGQSLTINCSTTCPDPGPSGIETFFKKTQLGKGPQWKEFLLEDVTENSVLQCFFSCGGVQKDTMLYITMFQPPEQVILDLQPEWVAMDEVFTVKCHVPGVAPLQSLTLTLLQGDQELHRKDFMSLSVASQRAEVTISVRAQRENDRCNFSCRAVLDLSPQGGGLFHGSSATKELRIFEFSQSPKIGVSSLLEVGVADTMNCEVSRVFPAQEAVFRMFLEDQELSPFSSWKGDAAWASATIRAMETGDQELTCLVSLGPMEQKVRRPVHVYSFPPPVLEVEDAYPLAGTDVNVTCSGHVLTSPSPTIRLQGAPNLSAPGEPAWFLFTAREEDDGRNLSCEATLEVQGQRLLKTTKIQLHVLYKPRFEESSCPGNQIWIEGMDQMLACIPQGNPTPALVCIWNGMVIDLDVPQKATQNHTGTYCCTATNQLGSVSKDIAVIVQGLHEGITSSTIFIIVISTLGMAVITIALYLNYQPCKRNRRKRAPRQREQNKDEESQFTDIQAEECNSHYC", "length": 548, "header": "tr|A0A9J7GER0-1|A0A9J7GER0_CRIGR Isoform 1 of Intercellular adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=LOC100751267 PE=3 SV=1 CANONICAL=A0A9J7GER0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GER0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0/entry#A0A9J7GER0-1", "sequence": { "sequence": "MKMLLLGIWTLLALIPCPGTTEELFEVSVWPNPALVKFGQSLTINCSTTCPDPGPSGIETFFKKTQLGKGPQWKEFLLEDVTENSVLQCFFSCGGVQKDTMLYITMFQPPEQVILDLQPEWVAMDEVFTVKCHVPGVAPLQSLTLTLLQGDQELHRKDFMSLSVASQRAEVTISVRAQRENDRCNFSCRAVLDLSPQGGGLFHGSSATKELRIFEFSQSPKIGVSSLLEVGVADTMNCEVSRVFPAQEAVFRMFLEDQELSPFSSWKGDAAWASATIRAMETGDQELTCLVSLGPMEQKVRRPVHVYSFPPPVLEVEDAYPLAGTDVNVTCSGHVLTSPSPTIRLQGAPNLSAPGEPAWFLFTAREEDDGRNLSCEATLEVQGQRLLKTTKIQLHVLYKPRFEESSCPGNQIWIEGMDQMLACIPQGNPTPALVCIWNGMVIDLDVPQKATQNHTGTYCCTATNQLGSVSKDIAVIVQGLHEGITSSTIFIIVISTLGMAVITIALYLNYQPCKRNRRKRAPRQREQNKDEESQFTDIQAEECNSHYC", "length": 548, "header": "tr|A0A9J7GER0-1|A0A9J7GER0_CRIGR Isoform 1 of Intercellular adhesion molecule 1 OS=Cricetulus griseus OX=10029 GN=LOC100751267 PE=3 SV=1 CANONICAL=A0A9J7GER0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GER0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GER0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751267", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751267", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GER0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GER0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GER0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0" } ], "pmid": "" }, { "name": "leukocyte cell-cell adhesion", "id": "GO:0007159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007159", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GER0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0" } ], "pmid": "" }, { "name": "leukocyte migration", "id": "GO:0050900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050900", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GER0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0" } ], "pmid": "" }, { "name": "cellular response to oxygen-containing compound", "id": "GO:1901701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901701", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GER0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0" } ], "pmid": "" }, { "name": "immune effector process", "id": "GO:0002252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002252", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GER0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GER0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GER0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 400, "end_pos": 474, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 350, "end_pos": 352 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GEU3-1", "uniprot_ac": "A0A9J7GEU3", "uniprot_id": "A0A9J7GEU3_CRIGR", "mass": { "chemical_mass": 106260.0, "monoisotopic_mass": 106260.0 }, "refseq": { "ac": "XP_003510038", "name": "patched domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510038" }, "gene_names": [ { "name": "Ptchd3", "type": "recommended", "evidence": [ { "id": "A0A9J7GEU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU3" } ] }, { "name": "Ptchd3", "type": "synonym", "evidence": [ { "id": "XP_003510038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510038" } ] } ], "protein_names": [ { "name": "Patched domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A9J7GEU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU3/entry#names_and_taxonomy" } ] }, { "name": "patched domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "XP_003510038", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510038" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614801.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510038" } ] }, { "annotation": "May play a role in sperm development or sperm function. However, does not appear to have an essential role in spermatogenesis or male fertility.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU3#function" }, { "database": "UniProtKB", "id": "ARBA00057027", "url": "https://www.uniprot.org/uniprotkb/ARBA00057027#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptchd3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU3", "locus": {} } ], "crossref": [ { "id": "A0A9J7GEU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7GEU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100752652", "url": "https://www.ncbi.nlm.nih.gov/gene/100752652", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752652", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752652", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GEU3", "url": "https://www.orthodb.org/?gene=A0A9J7GEU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10796", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10796", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10796:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10796:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02460", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02460", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510038", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510038", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GEU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7GEU5-1", "uniprot_ac": "A0A9J7GEU5", "uniprot_id": "A0A9J7GEU5_CRIGR", "mass": { "chemical_mass": 62545.0, "monoisotopic_mass": 62545.0 }, "refseq": { "ac": "XP_027284596", "name": "forkhead box protein J2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284596" }, "gene_names": [ { "name": "Foxj2", "type": "recommended", "evidence": [ { "id": "A0A9J7GEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5" } ] }, { "name": "Foxj2", "type": "synonym", "evidence": [ { "id": "XP_027284596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284596" } ] } ], "protein_names": [ { "name": "Forkhead box protein J2 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7GEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5/entry#names_and_taxonomy" } ] }, { "name": "forkhead box protein J2 isoform 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027284596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284596" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Foxj2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5", "locus": {} } ], "crossref": [ { "id": "cd20051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770857", "url": "https://www.ncbi.nlm.nih.gov/gene/100770857", "database": "GeneID", "categories": [ "Genome 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770857", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770857", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7GEU5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7GEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEU5" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": 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"A0A9J7JJ55", "uniprot_id": "A0A9J7JJ55_CRIGR", "mass": { "chemical_mass": 57921.0, "monoisotopic_mass": 57921.0 }, "refseq": { "ac": "XP_027262971", "name": "F-box/WD repeat-containing protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262971" }, "gene_names": [ { "name": "Fbxw4", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55" } ] }, { "name": "Fbxw4", "type": "synonym", "evidence": [ { "id": "XP_027262971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262971" } ] } ], "protein_names": [ { "name": "F-box/WD repeat-containing protein 4", "type": "recommended", "evidence": [ { "id": "A0A9J7JJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55/entry#names_and_taxonomy" } ] }, { "name": "F-box and WD-40 domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "A0A9J7JJ55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55/entry#names_and_taxonomy" } ] }, { "name": "F-box/WD repeat-containing protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027262971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262971" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027262971.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262971" } ] }, { "annotation": "Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55#function" }, { "database": "UniProtKB", "id": "ARBA00060163", "url": "https://www.uniprot.org/uniprotkb/ARBA00060163#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJ55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fbxw4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55", "locus": {} } ], "crossref": [ { "id": "A0A9J7JJ55", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JJ55", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20090", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20090", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751884", "url": "https://www.ncbi.nlm.nih.gov/gene/100751884", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751884", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751884", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JJ55", "url": "https://www.orthodb.org/?gene=A0A9J7JJ55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14381:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14381:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262971", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7FLK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FPC5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FPC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ55", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ55-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6H2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6H2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSQGRSGSPGNRGPREGEGGEARKLQEARVARGKRGKGPAGTGHGGRGSGAEGKPGLRPAAGAGPGRAGEEGGGVEEGPRSSGKRDEGSAGPGAGRREDGSPERAQERGCQAWGGPPGTRTAMAAAAEDEAAAAAVEPATRPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTRLGTDLMTSIPVKDRVKVSQNWRLGRCREGILLKWRCSQMPWMQLEGASLYISQANFILAYQFRPDGASLNRRPFRVFAGHDEDVCHFVLANSHIVSAGGDGKIGVHKLHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPILSSFVTGTACCGHFSPLRIWDLNSGQLITHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSARKCVMEWEEPHDSTLYCLQTDGNHLLATGSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRFTTRHLYAALSYNLHILDFQNP", "length": 533, "header": "tr|A0A9J7JJ55-1|A0A9J7JJ55_CRIGR Isoform 1 of F-box/WD repeat-containing protein 4 OS=Cricetulus griseus OX=10029 GN=Fbxw4 PE=4 SV=1 CANONICAL=A0A9J7JJ55-1" }, "isoforms": [ { "isoform_ac": "A0A9J7FLK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55/entry#A0A9J7FLK4-1", "sequence": { "sequence": "MVSPPLEEAAAATSASLRVERALRPLMGSQGRSGSPGNRGPREGEGGEARKLQEARVARGKRGKGPAGTGHGGRGSGAEGKPGLRPAAGAGPGRAGEEGGGVEEGPRSSGKRDEGSAGPGAGRREDGSPERAQERGCQAWGGPPGTRTAMAAAAEDEAAAAAVEPATRPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTRLGTDLMTSIPVKDRVKVSQNWRLGRCREGILLKWRCSQMPWMQLEGASLYISQANFILAYQFRPDGASLNRRPFRVFAGHDEDVCHFVLANSHIVSAGGDGKIGVHKLHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPILSSFVTGTACCGHFSPLRIWDLNSGQLITHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSARPAVLLDLWPCCPEAPPAALGAD", "length": 495, "header": "tr|A0A9J7FLK4-1|A0A9J7FLK4_CRIGR Computationally mapped isoform of F-box/WD repeat-containing protein 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Fbxw4 PE=4 SV=1 CANONICAL=A0A9J7JJ55-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FPC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55/entry#A0A9J7FPC5-1", "sequence": { "sequence": "MTSIPVKDRVKVSQNWRLGRCREGILLKWRCSQMPWMQLEGASLYISQANFILAYQFRPDGASLNRRPFRVFAGHDEDVCHFVLANSHIVSAGGDGKIGVHKLHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPILSSFVTGTACCGHFSPLRIWDLNSGQLITHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSARKCVMEWEEPHDSTLYCLQTDGNHLLATGSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRFTTRHLYAALSYNLHILDFQNP", "length": 325, "header": "tr|A0A9J7FPC5-1|A0A9J7FPC5_CRIGR Computationally mapped isoform of F-box/WD repeat-containing protein 4 isoform X5 OS=Cricetulus griseus OX=10029 GN=Fbxw4 PE=4 SV=1 CANONICAL=A0A9J7JJ55-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ55-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55/entry#A0A9J7JJ55-1", "sequence": { "sequence": "MGSQGRSGSPGNRGPREGEGGEARKLQEARVARGKRGKGPAGTGHGGRGSGAEGKPGLRPAAGAGPGRAGEEGGGVEEGPRSSGKRDEGSAGPGAGRREDGSPERAQERGCQAWGGPPGTRTAMAAAAEDEAAAAAVEPATRPAAGPALWRLPEELLLLICSYLDMRALGRLAQVCRWLRRFTSCDLLWRRIARASLNSGFTRLGTDLMTSIPVKDRVKVSQNWRLGRCREGILLKWRCSQMPWMQLEGASLYISQANFILAYQFRPDGASLNRRPFRVFAGHDEDVCHFVLANSHIVSAGGDGKIGVHKLHSTFTVKYSAHEQEVNCVDCKGGIIVSGSRDRTAKVWPLASGRLGQCLHTIQTEDRVWSIAISPILSSFVTGTACCGHFSPLRIWDLNSGQLITHLGSDFPPGAGVLDVMYESPSTLLSCGYDTYVRYWDLRTSARKCVMEWEEPHDSTLYCLQTDGNHLLATGSSYYGVVRLWDRRQRACLHAFPLTSTPLSSPVYCLRFTTRHLYAALSYNLHILDFQNP", "length": 533, "header": "tr|A0A9J7JJ55-1|A0A9J7JJ55_CRIGR Isoform 1 of F-box/WD repeat-containing protein 4 OS=Cricetulus griseus OX=10029 GN=Fbxw4 PE=4 SV=1 CANONICAL=A0A9J7JJ55-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K6H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ55/entry#A0A9J7K6H2-1", "sequence": { "sequence": 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"go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKC6" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JKC6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JKC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKC6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 388, "end_pos": 415, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JKC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKC6" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 233, "end_pos": 305, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JKC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKC6" }, { "id": "PS50804", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50804" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCAN box", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 127, "start_aa": "His", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 352, "end_pos": 354 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 369, "end_pos": 371 }, { "start_pos": 564, "end_pos": 566 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JJE4-1", "uniprot_ac": "A0A9J7JJE4", "uniprot_id": "A0A9J7JJE4_CRIGR", "mass": { "chemical_mass": 77661.0, "monoisotopic_mass": 77661.0 }, "refseq": { "ac": "XP_027273841", "name": "heterogeneous nuclear ribonucleoprotein M isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273841" }, "gene_names": [ { "name": "Hnrnpm", "type": "recommended", "evidence": [ { "id": "A0A9J7JJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ] }, { "name": "Hnrnpm", "type": "synonym", "evidence": [ { "id": "XP_027273841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273841" } ] } ], "protein_names": [ { "name": "Heterogeneous nuclear ribonucleoprotein M", "type": "recommended", "evidence": [ { "id": "A0A9J7JJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4/entry#names_and_taxonomy" } ] }, { "name": "heterogeneous nuclear ribonucleoprotein M isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027273841", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273841" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027273841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273841" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hnrnpm", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4", "locus": {} } ], "crossref": [ { "id": "A0A9J7JJE4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JJE4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12657", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12657", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12659", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12659", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753958", "url": "https://www.ncbi.nlm.nih.gov/gene/100753958", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753958", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753958", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JJE4", "url": "https://www.orthodb.org/?gene=A0A9J7JJE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23003:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23003:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027273841", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027273841", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G1B3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSI0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGVEAAAEVAATEPKMEEESGAPCVPSGNGAPGPKGEGERPTQNEKRKEKNIKRGGNRFEPYTNPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMINIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNLGPAGMGMEGIGFGINKIGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGAGGSVPGIERMGPGIDRIGGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIDRMGPIGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMDRMVPTGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGSAGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA", "length": 730, "header": "tr|A0A9J7JJE4-1|A0A9J7JJE4_CRIGR Isoform 1 of Heterogeneous nuclear ribonucleoprotein M OS=Cricetulus griseus OX=10029 GN=Hnrnpm PE=4 SV=1 CANONICAL=A0A9J7JJE4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G1B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4/entry#A0A9J7G1B3-1", "sequence": { "sequence": "MAAGVEAAAEVAATEPKMEEESGAPCVPSGNGAPGPKGEGERPTQNEKRKEKNIKRGGNRFEPYTNPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMINIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNLGPAGMGMEGIGFGINKIGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGAGGSVPGIERMGPGIDRIGGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIDRMGPIGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMDRMVPTGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGSAGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGDLD", "length": 680, "header": "tr|A0A9J7G1B3-1|A0A9J7G1B3_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein M isoform X5 OS=Cricetulus griseus OX=10029 GN=Hnrnpm PE=4 SV=1 CANONICAL=A0A9J7JJE4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4/entry#A0A9J7G1V0-1", "sequence": { "sequence": "MEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMINIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNLGPAGMGMEGIGFGINKIGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGAGGSVPGIERMGPGIDRIGGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIDRMGPIGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMDRMVPTGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGSAGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA", "length": 610, "header": "tr|A0A9J7G1V0-1|A0A9J7G1V0_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein M isoform X6 OS=Cricetulus griseus OX=10029 GN=Hnrnpm PE=4 SV=1 CANONICAL=A0A9J7JJE4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4/entry#A0A9J7JJE4-1", "sequence": { "sequence": "MAAGVEAAAEVAATEPKMEEESGAPCVPSGNGAPGPKGEGERPTQNEKRKEKNIKRGGNRFEPYTNPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMINIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNLGPAGMGMEGIGFGINKIGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGAGGSVPGIERMGPGIDRIGGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIDRMGPIGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMDRMVPTGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGSAGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA", "length": 730, "header": "tr|A0A9J7JJE4-1|A0A9J7JJE4_CRIGR Isoform 1 of Heterogeneous nuclear ribonucleoprotein M OS=Cricetulus griseus OX=10029 GN=Hnrnpm PE=4 SV=1 CANONICAL=A0A9J7JJE4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4/entry#A0A9J7JRA6-1", "sequence": { "sequence": "MAAGVEAAAEVAATEPKMEEESGAPCVPSGNGAPGPKGEGERPTQNEKRKEKNIKRGGNRFEPYTNPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNLGPAGMGMEGIGFGINKIGGMEGPFGGGMENMGRFGSGMNMGRINEILSNALKRGEIIAKQGGGGAGGSVPGIERMGPGIDRIGGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIDRMGPIGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMDRMVPTGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGSAGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA", "length": 691, "header": "tr|A0A9J7JRA6-1|A0A9J7JRA6_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein M OS=Cricetulus griseus OX=10029 GN=Hnrnpm PE=4 SV=1 CANONICAL=A0A9J7JJE4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4/entry#A0A9J7JSI0-1", "sequence": { "sequence": "MAAGVEAAAEVAATEPKMEEESGAPCVPSGNGAPGPKGEGERPTQNEKRKEKNIKRGGNRFEPYTNPTKRYRAFITNIPFDVKWQSLKDLVKEKVGEVTYVELLMDAEGKSRGCAVVEFKMEESMKKAAEVLNKHSLSGRPLKVKEDPDGEHARRAMQKVMATTGGMGMGPGGPGMINIPPSILNNPNIPNEIIHALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSRGIGTVTFEQSIEAVQAISMFNGQLLFDRPMHVKMDERALPKGDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNKGIGMGNLGPAGMGMEGIGFGINKIGGMEGPFGGGMENMGRFGSGMNMGRINGGAGGSVPGIERMGPGIDRIGGAGMERMGAGLGHGMDRVGSEIERMGLVMDRMGSVERMGSGIDRMGPIGLDHMASSIERMGQTMERIGSGVERMGAGMGFGLERMAAPIDRVGQTIERMGSGVERMGPAIERMGLSMDRMVPTGMGAGLERMGPVMDRMATGLERMGANNLERMGLERMGANSLERMGLERMGANSLERMGPAMGPALGAGIERMGLAMGSAGGASFDRAIEMERGNFGGSFAGSFGGAGGHAPGVARKACQIFVRNLPFDFTWKMLKDKFNECGHVLYADIKMENGKSKGCGVVKFESPEVAERACRMMNGMKLSGREIDVRIDRNA", "length": 712, "header": "tr|A0A9J7JSI0-1|A0A9J7JSI0_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein M OS=Cricetulus griseus OX=10029 GN=Hnrnpm PE=4 SV=1 CANONICAL=A0A9J7JJE4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753958", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753958", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ], "pmid": "" }, { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JJE4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJE4" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 149, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JII9-1", "uniprot_ac": "A0A9J7JII9", "uniprot_id": "A0A9J7JII9_CRIGR", "mass": { "chemical_mass": 59400.0, "monoisotopic_mass": 59400.0 }, "refseq": { "ac": "XP_027272228", "name": "zinc finger protein 431 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272228" }, "gene_names": [ { "name": "LOC100762252", "type": "recommended", "evidence": [ { "id": "A0A9J7JII9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JII9" } ] }, { "name": "LOC100762252", "type": "synonym", "evidence": [ { "id": "XP_027272228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272228" } ] } ], "protein_names": [ { "name": "Zinc finger protein 431 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7JII9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JII9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 431 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027272228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272228" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272228" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JII9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JII9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100762252", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JII9", "locus": {} } ], "crossref": [ { "id": "A0A9J7JII9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JII9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762252", "url": "https://www.ncbi.nlm.nih.gov/gene/100762252", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762252", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762252", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JII9", "url": "https://www.orthodb.org/?gene=A0A9J7JII9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23232:SF151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23232:SF151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24399:SF71", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24399:SF71", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027272228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272228", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7G1L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZA8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JII9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JII9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JII9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JII9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAVTYEDVHVNFTQEEWALLDPSQKSLYKDVMLETWENLISIGYKWEDPNIEDHCQSPRKHGRYMICHCGYKPCDPKGYGKRQCSSVSSRKVVPTVTRHSGHDTSVGLIEFPASMGIHQQTHVVCPGSCCPCNVTDTTGKCYEFDKYGKTLSSSGSLQRCEKTHMGKECCKCEPRTKGLNHHMYLQAHKRTHHEEEPCKCKHHDKTFSSDSSLKLHQRMHLKMKPYEYNQGVKDFACHSYLQVPKIHTGKKPYECHQCGKAFARPSERKIHERSHTGEKPYECSQCGKTFAYPSSLQRHERNHTVEKPFECHQCGKAFVHNSHLQRHERSHSGAKRYECSQCGKVFAHNSHLQRHERSHTGERPYECNQCGIAFSSRSNLLSHERSHAGVKPYGCNQCGKAFARKSHLQYHERIHTREKSHEPHKRGKALHKKQRYHHFGGTSTMGCPPRPSAMVKWNQPEPRREVVCAAEAGASVATQALWRSPGDCEWIPGISSGVIYTVGVCFSFFQNVSTLILPS", "length": 520, "header": "tr|A0A9J7JII9-1|A0A9J7JII9_CRIGR Isoform 1 of Zinc finger protein 431 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100762252 PE=3 SV=1 CANONICAL=A0A9J7JII9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7G1L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JII9/entry#A0A9J7G1L4-1", "sequence": { "sequence": "MDAVTYEDVHVNFTQEEWALLDPSQKSLYKDVMLETWENLISIGYKWEDPNIEDHCQSPRKHGR", "length": 64, "header": "tr|A0A9J7G1L4-1|A0A9J7G1L4_CRIGR Computationally mapped isoform of Zinc finger protein 431 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100762252 PE=4 SV=1 CANONICAL=A0A9J7JII9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JII9/entry#A0A9J7GZA8-1", "sequence": { "sequence": "MLETWENLISIGYKWEDPNIEDHCQSPRKHGRYMICHCGYKPCDPKGYGKRQCSSVSSRKVVPTVTRHSGHDTSVGLIEFPASMGIHQQTHVVCPGSCCPCNVTDTTGKCYEFDKYGKTLSSSGSLQRCEKTHMGKECCKCEPRTKGLNHHMYLQAHKRTHHEEEPCKCKHHDKTFSSDSSLKLHQRMHLKMKPYEYNQGVKDFACHSYLQVPKIHTGKKPYECHQCGKAFARPSERKIHERSHTGEKPYECSQCGKTFAYPSSLQRHERNHTVEKPFECHQCGKAFVHNSHLQRHERSHSGAKRYECSQCGKVFAHNSHLQRHERSHTGERPYECNQCGIAFSSRSNLLSHERSHAGVKPYGCNQCGKAFARKSHLQYHERIHTREKSHEPHKRGKALHKKQRYHHFGGTSTMGCPPRPSAMVKWNQPEPRREVVCAAEAGASVATQALWRSPGDCEWIPGISSGVIYTVGVCFSFFQNVSTLILPS", "length": 488, "header": "tr|A0A9J7GZA8-1|A0A9J7GZA8_CRIGR Computationally mapped isoform of Zinc finger protein 431 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100762252 PE=3 SV=1 CANONICAL=A0A9J7JII9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JII9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JII9/entry#A0A9J7JII9-1", "sequence": { "sequence": "MDAVTYEDVHVNFTQEEWALLDPSQKSLYKDVMLETWENLISIGYKWEDPNIEDHCQSPRKHGRYMICHCGYKPCDPKGYGKRQCSSVSSRKVVPTVTRHSGHDTSVGLIEFPASMGIHQQTHVVCPGSCCPCNVTDTTGKCYEFDKYGKTLSSSGSLQRCEKTHMGKECCKCEPRTKGLNHHMYLQAHKRTHHEEEPCKCKHHDKTFSSDSSLKLHQRMHLKMKPYEYNQGVKDFACHSYLQVPKIHTGKKPYECHQCGKAFARPSERKIHERSHTGEKPYECSQCGKTFAYPSSLQRHERNHTVEKPFECHQCGKAFVHNSHLQRHERSHSGAKRYECSQCGKVFAHNSHLQRHERSHTGERPYECNQCGIAFSSRSNLLSHERSHAGVKPYGCNQCGKAFARKSHLQYHERIHTREKSHEPHKRGKALHKKQRYHHFGGTSTMGCPPRPSAMVKWNQPEPRREVVCAAEAGASVATQALWRSPGDCEWIPGISSGVIYTVGVCFSFFQNVSTLILPS", "length": 520, "header": "tr|A0A9J7JII9-1|A0A9J7JII9_CRIGR Isoform 1 of Zinc finger protein 431 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100762252 PE=3 SV=1 CANONICAL=A0A9J7JII9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JII9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JII9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264568" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kmt5b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86", "locus": {} } ], "crossref": [ { "id": "A0A9J7JI86", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JI86", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19184", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19184", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GTC4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GTC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKDNATSNRKSSVGVKKSSKSRTLTRQSMPRVPAASNSTSPKLTHMNNSRVPKKLRKPAKPLLSKIKLRNHCKRLDQKNASRKLEMGNLVLKEPKVVLYKNLPIKKEKEPEGPEQAAVGSGCLTRHAAREHRQNPGRGAHSQGDSLPCTYTTRRSLRTRTGLKEATDIKLEPSPLDGYKNGLLEPCPDSDQHPTPEVLEELAPETAHMEEASQECPKSDPCPSRKKFRQGKPMKHLAKAEDCSLEHGFPGKDGLPDLPVPHPDQGEPSGTIGVPVSYTDSAPSPVGCSIVTPDSFTTKDSFRTAQSKKKRRVTRYDAQLILENSSGIPKLTLRRRHDSSSKTNDHESDGMNSKISIKLSKDHESDSNLYVAKLSNGVSSGPGGSSTKLKIQLKRDEESRGPYAEGLHENGVCCSDPLSLLESQMEVDDYSQYEEDSTDDSSSSEGEEEEEDCEDDFDDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA", "length": 695, "header": "tr|A0A9J7JI86-1|A0A9J7JI86_CRIGR Isoform 1 of [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B OS=Cricetulus griseus OX=10029 GN=Kmt5b PE=4 SV=1 CANONICAL=A0A9J7JI86-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GTC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86/entry#A0A9J7GTC4-1", "sequence": { "sequence": "MKWLGDSKNMVVNGRRNGGKLSNDHQQNQSKLQHSGKDTLKTGRNAVERRSNRCHGNSGFEGQSRYVPSSGMSAKELCENDDLATSLVLDPYLGFQTHKMNTSAFPLRSSRHISKADSFSHNNPVRFRPIKGRQEELKEVIERFKKDEHLEKAFKCLTSGEWARHYFLNKNKMQEKLFKEHVFIYLRMFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDLISS", "length": 278, "header": "tr|A0A9J7GTC4-1|A0A9J7GTC4_CRIGR Computationally mapped isoform of Histone-lysine N-methyltransferase KMT5B isoform X2 OS=Cricetulus griseus OX=10029 GN=Kmt5b PE=4 SV=1 CANONICAL=A0A9J7JI86-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JI86-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86/entry#A0A9J7JI86-1", "sequence": { "sequence": "MFATDSGFEILPCNRYSSEQNGAKIVATKEWKRNDKIELLVGCIAELSEIEENMLLRHGENDFSVMYSTRKNCAQLWLGPAAFINHDCRPNCKFVSTGRDTACVKALRDIEPGEEISCYYGDGFFGENNEFCECYTCERRGTGAFKSRVGLPAPAPVINSKYGLRETDKRLNRLKKLGDSSKNSDSQSVSSNTDADTTQEKDNATSNRKSSVGVKKSSKSRTLTRQSMPRVPAASNSTSPKLTHMNNSRVPKKLRKPAKPLLSKIKLRNHCKRLDQKNASRKLEMGNLVLKEPKVVLYKNLPIKKEKEPEGPEQAAVGSGCLTRHAAREHRQNPGRGAHSQGDSLPCTYTTRRSLRTRTGLKEATDIKLEPSPLDGYKNGLLEPCPDSDQHPTPEVLEELAPETAHMEEASQECPKSDPCPSRKKFRQGKPMKHLAKAEDCSLEHGFPGKDGLPDLPVPHPDQGEPSGTIGVPVSYTDSAPSPVGCSIVTPDSFTTKDSFRTAQSKKKRRVTRYDAQLILENSSGIPKLTLRRRHDSSSKTNDHESDGMNSKISIKLSKDHESDSNLYVAKLSNGVSSGPGGSSTKLKIQLKRDEESRGPYAEGLHENGVCCSDPLSLLESQMEVDDYSQYEEDSTDDSSSSEGEEEEEDCEDDFDDDFIPLPPAKRLRLIVGKDSIDIDISSRRREDQSLRLNA", "length": 695, "header": "tr|A0A9J7JI86-1|A0A9J7JI86_CRIGR Isoform 1 of [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B OS=Cricetulus griseus OX=10029 GN=Kmt5b PE=4 SV=1 CANONICAL=A0A9J7JI86-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "methylation", "id": "GO:0032259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032259", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "pmid": "" }, { "name": "muscle organ development", "id": "GO:0007517", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007517", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "histone H4K20 methyltransferase activity", "id": "GO:0042799", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042799", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "pmid": "" }, { "name": "histone H4K20me methyltransferase activity", "id": "GO:0140941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140941", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "pmid": "" }, { "name": "histone H4K20 monomethyltransferase activity", "id": "GO:0140944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140944", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "60344", "name": "", "equation": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3I4X7-1", "A0A9J7GYF1-1", "A0A8C2MPE8-1", "A0A8C2MJ89-1", "A0A8C2QMN0-1", "A0A9J7KDN5-1", "A0A9J7JI86-1", "A0A9J7J9K1-1" ], "evidence": [ { "id": "60344", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60344" } ] }, { "id": "60348", "name": "", "equation": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7GYF1-1", "A0A8C2MPE8-1", "A0A9J7GIF1-1", "A0A9J7JI86-1", "A0A9J7J9K1-1" ], "evidence": [ { "id": "60348", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/60348" } ] }, { "id": "61992", "name": "", "equation": "N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7GYF1-1", "A0A8C2MPE8-1", "A0A9J7GIF1-1", "A0A9J7JI86-1" ], "evidence": [ { "id": "61992", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/61992" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8C2MJ89", "gene_name": "Prdm6", "activity": [ { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8C2MJ89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ89" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A8C2MJ89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ89" } ] } ] }, { "uniprot_ac": "A0A8C2MPE8", "gene_name": "Kmt5b", "activity": [ { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8C2MPE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPE8" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8C2MPE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPE8" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A8C2MPE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPE8" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A8C2MPE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPE8" } ] } ] }, { "uniprot_ac": "A0A8C2QMN0", "gene_name": "Kmt5a", "activity": [ { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A8C2QMN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMN0" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A8C2QMN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMN0" } ] } ] }, { "uniprot_ac": "A0A9J7GIF1", "gene_name": "Kmt5c", "activity": [ { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A9J7GIF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIF1" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A9J7GIF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIF1" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A9J7GIF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIF1" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A9J7GIF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIF1" } ] } ] }, { "uniprot_ac": "A0A9J7GYF1", "gene_name": "Setd4", "activity": [ { "ec_number": "2.1.1.364", "activity": "L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A9J7GYF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYF1" } ] }, { "ec_number": "2.1.1.364", "activity": "", "evidence": [ { "id": "A0A9J7GYF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYF1" } ] } ] }, { "uniprot_ac": "A0A9J7J9K1", "gene_name": "LOC100752747", "activity": [ { "ec_number": "2.1.1.359", "activity": "L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A9J7J9K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9K1" } ] }, { "ec_number": "2.1.1.355", "activity": "L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A9J7J9K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9K1" } ] }, { "ec_number": "2.1.1.354", "activity": "L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+).", "evidence": [ { "id": "A0A9J7J9K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9K1" } ] }, { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A9J7J9K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9K1" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A9J7J9K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9K1" } ] }, { "ec_number": "2.1.1.359", "activity": "", "evidence": [ { "id": "A0A9J7J9K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9K1" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A9J7J9K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9K1" } ] }, { "ec_number": "2.1.1.354", "activity": "", "evidence": [ { "id": "A0A9J7J9K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9K1" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A9J7J9K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9K1" } ] }, { "ec_number": "2.1.1.355", "activity": "", "evidence": [ { "id": "A0A9J7J9K1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9K1" } ] } ] }, { "uniprot_ac": "A0A9J7JI86", "gene_name": "Kmt5b", "activity": [ { "ec_number": "2.1.1.362", "activity": "N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A9J7JI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ] }, { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A9J7JI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ] }, { "ec_number": "2.1.1.362", "activity": "", "evidence": [ { "id": "A0A9J7JI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A9J7JI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" } ] } ] }, { "uniprot_ac": "A0A9J7KDN5", "gene_name": "LOC100750585", "activity": [ { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "A0A9J7KDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDN5" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "A0A9J7KDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDN5" } ] } ] }, { "uniprot_ac": "G3I4X7", "gene_name": "Kmt5a", "activity": [ { "ec_number": "2.1.1.361", "activity": "L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+).", "evidence": [ { "id": "G3I4X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I4X7" } ] }, { "ec_number": "2.1.1.361", "activity": "", "evidence": [ { "id": "G3I4X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I4X7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JI86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI86" }, { "id": "PS50280", 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027261566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261566" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI67" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100763140", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI67", "locus": {} } ], "crossref": [ { "id": "A0A9J7JI67", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JI67", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00312", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00312", "database": "CDD", "categories": [ "Protein 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"MTLQSLPGWLNAVTCGLLLLFLHVQGQDSASPIRNTRTGQVRGSLVRVKNTEVDVHTFLGIPFAKPPIGPLRFAPPESPEPWSGVRDGTSYPAMCLQNDDMMNSEALKMMKFIMPPIATSEDCLYLNIYTPTHAHEGSNLPVMVWIHGGALVVGLASMYDGSMLAAIEDVVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVAVLPDLISSSSEMVYTIVANLSDCGAVNTETLVSCLRGKSEAEILDINKVFKIIPAVVDGEFLPKHPLELLASADFHPVPSIIGVNNDEYGWLLPMIMGSAQKIKEITKETLPAIMKSTAAQMNLPPECSDLLMEEYMGDTEDPQTLQIQFTEMMGDFMFVIPALKVAHFQRSHAPVFFYEFQHRPSFLKDIKPPHVKADHGDDFFFIFGNLLFGVKFASTEEEELLSRKMMKYWANFARHGNPNSEGLPYWPMLDHDEQYLQLNIHPAVGRALKARRLQFWTKTLPQKIQELKGTQERHKEL", "length": 559, "header": "tr|A0A9J7JI67-1|A0A9J7JI67_CRIGR Isoform 1 of Carboxylic ester hydrolase OS=Cricetulus griseus OX=10029 GN=LOC100763140 PE=3 SV=1 CANONICAL=A0A9J7JI67-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GQS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI67/entry#A0A9J7GQS5-1", "sequence": { "sequence": "MTLQSLPGWLNAVTCGLLLLFLHVQGQDSASPIRNTRTGQVRGSLVRVKNTEVDVHTFLGIPFAKPPIGPLRFAPPESPEPWSGVRDGTSYPAMCLQNDDMMNSEALKMMKFIMPPIATSEDCLYLNIYTPTHAHEGSNLPVMVWIHGGALVVGLASMYDGSMLAAIEDVVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVAVLPDLISSSSEMVYTVFKIIPAVVDGEFLPKHPLELLASADFHPVPSIIGVNNDEYGWLLPMIMGSAQKIKEITKETLPAIMKSTAAQMNLPPECSDLLMEEYMGDTEDPQTLQIQFTEMMGDFMFVIPALKVAHFQRSHAPVFFYEFQHRPSFLKDIKPPHVKADHGDDFFFIFGNLLFGVKFASTEEEELLSRKMMKYWANFARHGNPNSEGLPYWPMLDHDEQYLQLNIHPAVGRALKARRLQFWTKTLPQKIQELKGTQERHKEL", "length": 526, "header": "tr|A0A9J7GQS5-1|A0A9J7GQS5_CRIGR Computationally mapped isoform of Carboxylic ester hydrolase OS=Cricetulus griseus OX=10029 GN=LOC100763140 PE=3 SV=1 CANONICAL=A0A9J7JI67-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GW15-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI67/entry#A0A9J7GW15-1", "sequence": { "sequence": "MTLQSLPGWLNAVTCGLLLLFLHVQGQDSASPIRNTRTGQVRGSLVRVKNTEVDVHTFLGIPFAKPPIGPLRFAPPESPEPWSGVRDGTSYPAMCLQNDDMMNSEALKMMKFIMPPIATSEDCLYLNIYTPTHAHEGSNLPIVANLSDCGAVNTETLVSCLRGKSEAEILDINKVFKIIPAVVDGEFLPKHPLELLASADFHPVPSIIGVNNDEYGWLLPMIMGSAQKIKEITKETLPAIMKSTAAQMNLPPECSDLLMEEYMGDTEDPQTLQIQFTEMMGDFMFVIPALKVAHFQRSHAPVFFYEFQHRPSFLKDIKPPHVKADHGDDFFFIFGNLLFGVKFASTEEEELLSRKMMKYWANFARHGNPNSEGLPYWPMLDHDEQYLQLNIHPAVGRALKARRLQFWTKTLPQKIQELKGTQERHKEL", "length": 428, "header": "tr|A0A9J7GW15-1|A0A9J7GW15_CRIGR Computationally mapped isoform of Pyrethroid hydrolase Ces2e isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100763140 PE=3 SV=1 CANONICAL=A0A9J7JI67-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JI67-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI67/entry#A0A9J7JI67-1", "sequence": { "sequence": "MTLQSLPGWLNAVTCGLLLLFLHVQGQDSASPIRNTRTGQVRGSLVRVKNTEVDVHTFLGIPFAKPPIGPLRFAPPESPEPWSGVRDGTSYPAMCLQNDDMMNSEALKMMKFIMPPIATSEDCLYLNIYTPTHAHEGSNLPVMVWIHGGALVVGLASMYDGSMLAAIEDVVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSHVVSPMSQGLFHGAIMESGVAVLPDLISSSSEMVYTIVANLSDCGAVNTETLVSCLRGKSEAEILDINKVFKIIPAVVDGEFLPKHPLELLASADFHPVPSIIGVNNDEYGWLLPMIMGSAQKIKEITKETLPAIMKSTAAQMNLPPECSDLLMEEYMGDTEDPQTLQIQFTEMMGDFMFVIPALKVAHFQRSHAPVFFYEFQHRPSFLKDIKPPHVKADHGDDFFFIFGNLLFGVKFASTEEEELLSRKMMKYWANFARHGNPNSEGLPYWPMLDHDEQYLQLNIHPAVGRALKARRLQFWTKTLPQKIQELKGTQERHKEL", "length": 559, "header": "tr|A0A9J7JI67-1|A0A9J7JI67_CRIGR Isoform 1 of Carboxylic ester hydrolase OS=Cricetulus griseus OX=10029 GN=LOC100763140 PE=3 SV=1 CANONICAL=A0A9J7JI67-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI67" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI67" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763140", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI67", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JIP0-1", "uniprot_ac": "A0A9J7JIP0", "uniprot_id": "A0A9J7JIP0_CRIGR", "mass": { "chemical_mass": 132034.0, "monoisotopic_mass": 132034.0 }, "refseq": { "ac": "XP_027261639", "name": "rho family-interacting cell polarization regulator 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261639" }, "gene_names": [ { "name": "Ripor1", "type": "recommended", "evidence": [ { "id": "A0A9J7JIP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0" } ] }, { "name": "Ripor1", "type": "synonym", "evidence": [ { "id": "XP_027261639", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261639" } ] } ], "protein_names": [ { "name": "Rho family-interacting cell polarization regulator 1", "type": "recommended", "evidence": [ { "id": "A0A9J7JIP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0/entry#names_and_taxonomy" } ] }, { "name": "rho family-interacting cell polarization regulator 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027261639", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261639" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027261639", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261639" } ] }, { "annotation": "Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0#function" }, { "database": "UniProtKB", "id": "ARBA00054594", "url": "https://www.uniprot.org/uniprotkb/ARBA00054594#function" }, { "database": "UniProtKB", "id": "A0A9J7K773", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K773#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ripor1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0", "locus": {} } ], "crossref": [ { "id": "A0A9J7JIP0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JIP0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100762946", "url": "https://www.ncbi.nlm.nih.gov/gene/100762946", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762946", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762946", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JIP0", "url": "https://www.orthodb.org/?gene=A0A9J7JIP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027261639", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261639", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GWW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K773", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K773", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K773-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K773-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSLSVRPQRRLLSARVNRSQSFAGVLGSHERGPRSFTVFSPPGPPRKPLVLSRVSRMFSVAHPAPKVPQPERLDLVYAALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLENELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVIWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSTPKPLVQQPEPLPIQVAFRRPETLTSGSMDEEPAVSPALVNGHAPYSRTLSHISEASVDAALTEAVEVVGSESLTPGPSPLAYPDSIHVEHLSSVPPILDAGHSATRPTPSTTGPSPTLIDPASSTQLDLVHKATDSNPSELPSLKHTCSTYSAVSPINSVPNITSTTIDSIHKPMPSTLTTTGSIPNAADPVQATPSPTHTTITLTHTTVSPTHSTPSPTHTSVSPTCTVPSATNATPSPSYNTTSPIQKTGMSTHATTSHTTNAMDPVLTTTSPISTTESPNSAIDLALTSSSSADLTLPGTKPLPCSHSASTPYTKTDPTASCTSSQSLACSGSETLTSPAPNSPEQILKSPRFSPSSIAPAPQHSELSPATAAQAPVPEATGGAGDKRLEEALGTLMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNDDEDEDSGARPTSSPEAVAEDRLDSSNAQSLSTGCPALDATLVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEEVCERSKLWGNSASSAQEVVQFSASRSGFLTFWDQCTEGLNPFICPVEQVLLTFCSQYGARLSLRQPGLAEAVCLKFLEDALGRKLPRRPQPGPGEQFTIFQFWIYVEALDSPSMDAYVTETAEEVLLVQNLNSDDQAVVLKALRLAPEGRLRRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPVFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPRIFGPSSMASTAF", "length": 1217, "header": "tr|A0A9J7JIP0-1|A0A9J7JIP0_CRIGR Isoform 1 of Rho family-interacting cell polarization regulator 1 OS=Cricetulus griseus OX=10029 GN=Ripor1 PE=3 SV=1 CANONICAL=A0A9J7JIP0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GWW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0/entry#A0A9J7GWW2-1", "sequence": { "sequence": "MMSLSVRPQRRLLSARVNRSQSFAGVLGSHERGPRSFTVFSPPGPPRKPLVLSRVSRMFSVAHPAPKVPQPERLDLVYAALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLENELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVIWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSTPKPLVQQPEPLPIQVAFRRPETLTSGSMDEEPAVSPALVNGHAPYSRTLSHISEASVDAALTEAVEVVGSESLTPGPSPLAYPDSIHVEHLSSVPPILDAGHSATRPTPSTTGPSPTLIDPASSTQLDLVHKATDSNPSELPSLKHTCSTYSAVSPINSVPNITSTTIDSIHKPMPSTLTTTGSIPNAADPVQATPSPTHTTITLTHTTVSPTHSTPSPTHTSVSPTCTVPSATNATPSPSYNTTSPIQKTGMSTHATTSHTTNAMDPVLTTTSPISTTESPNSAIDLALTSSSSADLTLPGTKPLPCSHSASTPYTKTDPTASCTSSQSLACSGSETLTSPAPNSPEQILKSPRFSPSSIAPAPQHSELSPATAAQAPVPEATGGAGDKRLEEALGTLMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNDDEDEDSGASVSGHPAHLCNVCLPCKSPSACEPPASLLSLDLTLDSPCEGVLSVPPHVCCVPQYQPPPSRSRLSRRSRSLSSHSWSRLYRFRFESRTRSLLPLRLPRFQSQALRPLQSTFYRPSRLQPYWRPSQAQKPLWS", "length": 996, "header": "tr|A0A9J7GWW2-1|A0A9J7GWW2_CRIGR Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ripor1 PE=3 SV=1 CANONICAL=A0A9J7JIP0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0/entry#A0A9J7JIP0-1", "sequence": { "sequence": "MMSLSVRPQRRLLSARVNRSQSFAGVLGSHERGPRSFTVFSPPGPPRKPLVLSRVSRMFSVAHPAPKVPQPERLDLVYAALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLENELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVIWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSTPKPLVQQPEPLPIQVAFRRPETLTSGSMDEEPAVSPALVNGHAPYSRTLSHISEASVDAALTEAVEVVGSESLTPGPSPLAYPDSIHVEHLSSVPPILDAGHSATRPTPSTTGPSPTLIDPASSTQLDLVHKATDSNPSELPSLKHTCSTYSAVSPINSVPNITSTTIDSIHKPMPSTLTTTGSIPNAADPVQATPSPTHTTITLTHTTVSPTHSTPSPTHTSVSPTCTVPSATNATPSPSYNTTSPIQKTGMSTHATTSHTTNAMDPVLTTTSPISTTESPNSAIDLALTSSSSADLTLPGTKPLPCSHSASTPYTKTDPTASCTSSQSLACSGSETLTSPAPNSPEQILKSPRFSPSSIAPAPQHSELSPATAAQAPVPEATGGAGDKRLEEALGTLMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNDDEDEDSGARPTSSPEAVAEDRLDSSNAQSLSTGCPALDATLVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEEVCERSKLWGNSASSAQEVVQFSASRSGFLTFWDQCTEGLNPFICPVEQVLLTFCSQYGARLSLRQPGLAEAVCLKFLEDALGRKLPRRPQPGPGEQFTIFQFWIYVEALDSPSMDAYVTETAEEVLLVQNLNSDDQAVVLKALRLAPEGRLRRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPVFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPRIFGPSSMASTAF", "length": 1217, "header": "tr|A0A9J7JIP0-1|A0A9J7JIP0_CRIGR Isoform 1 of Rho family-interacting cell polarization regulator 1 OS=Cricetulus griseus OX=10029 GN=Ripor1 PE=3 SV=1 CANONICAL=A0A9J7JIP0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K773-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0/entry#A0A9J7K773-1", "sequence": { "sequence": "MSFTVFSPPGPPRKPLVLSRVSRMFSVAHPAPKVPQPERLDLVYAALKRGLTAYLEVHQQEQEKLQGQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLENELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVIWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSSTPKPLVQQPEPLPIQVAFRRPETLTSGSMDEEPAVSPALVNGHAPYSRTLSHISEASVDAALTEAVEVVGSESLTPGPSPLAYPDSIHVEHLSSVPPILDAGHSATRPTPSTTGPSPTLIDPASSTQLDLVHKATDSNPSELPSLKHTCSTYSAVSPINSVPNITSTTIDSIHKPMPSTLTTTGSIPNAADPVQATPSPTHTTITLTHTTVSPTHSTPSPTHTSVSPTCTVPSATNATPSPSYNTTSPIQKTGMSTHATTSHTTNAMDPVLTTTSPISTTESPNSAIDLALTSSSSADLTLPGTKPLPCSHSASTPYTKTDPTASCTSSQSLACSGSETLTSPAPNSPEQILKSPRFSPSSIAPAPQHSELSPATAAQAPVPEATGGAGDKRLEEALGTLMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNDDEDEDSGARPTSSPEAVAEDRLDSSNAQSLSTGCPALDATLVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEEVCERSKLWGNSASSAQEVVQFSASRSGFLTFWDQCTEGLNPFICPVEQVLLTFCSQYGARLSLRQPGLAEAVCLKFLEDALGRKLPRRPQPGPGEQFTIFQFWIYVEALDSPSMDAYVTETAEEVLLVQNLNSDDQAVVLKALRLAPEGRLRRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPVFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPRIFGPSSMASTAF", "length": 1183, "header": "tr|A0A9J7K773-1|A0A9J7K773_CRIGR Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Cricetulus griseus OX=10029 GN=Ripor1 PE=3 SV=1 CANONICAL=A0A9J7JIP0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 507, "start_aa": "Thr", "end_pos": 507, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr507", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 594, "start_aa": "Thr", "end_pos": 594, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr594", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 636, "start_aa": "Thr", "end_pos": 636, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr636", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762946", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762946", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JIP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIP0" }, { "id": "PF15903", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM65 N-terminal", 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], "protein_names": [ { "name": "Vacuolar protein sorting-associated protein 33B", "type": "recommended", "evidence": [ { "id": "A0A9J7JHU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU1/entry#names_and_taxonomy" } ] }, { "name": "vacuolar protein sorting-associated protein 33B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007652588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652588" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616436.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007652588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652588" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Vps33b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU1", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHU1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100771457", "url": "https://www.ncbi.nlm.nih.gov/gene/100771457", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771457", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771457", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M2L1", "url": "https://www.orthodb.org/?gene=A0A8C2M2L1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JDN9", "url": "https://www.orthodb.org/?gene=A0A9J7JDN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JHU1", "url": "https://www.orthodb.org/?gene=A0A9J7JHU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JKH4", "url": "https://www.orthodb.org/?gene=A0A9J7JKH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11679", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11679", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007652588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007652588", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M2L1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2L1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M2L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2L1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDN9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JDN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKH4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JKH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKH4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFPHRLDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPALSSNEQLCFLVRPRIKNMRYIANLVNADKLAGRFRKYKVILTPQKFYACEMVLEEEGVYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRCAKMSYDLWRKLEEEEDSETKGRRPEIGHIFLLDRDMDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFNEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVENKVSKLVTDKAADTRWNLAQISSPGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRSWQGLDEVVRLLNCSEFAFTDMAKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAITNSARLMEAMSEVKA", "length": 629, "header": "tr|A0A9J7JHU1-1|A0A9J7JHU1_CRIGR Isoform 1 of Vacuolar protein sorting-associated protein 33B OS=Cricetulus griseus OX=10029 GN=Vps33b PE=3 SV=1 CANONICAL=A0A9J7JHU1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M2L1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU1/entry#A0A8C2M2L1-1", "sequence": { "sequence": "MAFPHRLDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPALSSNEQLCFLVRPRIKNMRYIANLVNADKLAGRFRKYKVILTPQKFYACEMVLEEEGVYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRCAKMSYDLWRKLEEEEDSETKGRRPEIGHIFLLDRDMDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFNEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVENKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRSWQGLDEVVRLLNCSEFAFTDMAKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAITNSARLMEAMSEVKA", "length": 617, "header": "tr|A0A8C2M2L1-1|A0A8C2M2L1_CRIGR Computationally mapped isoform of Vacuolar protein sorting-associated protein 33B OS=Cricetulus griseus OX=10029 GN=Vps33b PE=3 SV=1 CANONICAL=A0A9J7JHU1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JDN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU1/entry#A0A9J7JDN9-1", "sequence": { "sequence": "MACCAELLLSIDLVNADKLAGRFRKYKVILTPQKFYACEMVLEEEGVYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRCAKMSYDLWRKLEEEEDSETKGRRPEIGHIFLLDRDMDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFNEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVENKVSKLVTDKAADTRWNLAQISSPGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRSWQGLDEVVRLLNCSEFAFTDMAKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAITNSARLMEAMSEVKA", "length": 544, "header": "tr|A0A9J7JDN9-1|A0A9J7JDN9_CRIGR Computationally mapped isoform of Vacuolar protein sorting-associated protein 33B isoform X3 OS=Cricetulus griseus OX=10029 GN=Vps33b PE=3 SV=1 CANONICAL=A0A9J7JHU1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU1/entry#A0A9J7JHU1-1", "sequence": { "sequence": "MAFPHRLDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKPALSSNEQLCFLVRPRIKNMRYIANLVNADKLAGRFRKYKVILTPQKFYACEMVLEEEGVYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRCAKMSYDLWRKLEEEEDSETKGRRPEIGHIFLLDRDMDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFNEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVENKVSKLVTDKAADTRWNLAQISSPGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRSWQGLDEVVRLLNCSEFAFTDMAKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAITNSARLMEAMSEVKA", "length": 629, "header": "tr|A0A9J7JHU1-1|A0A9J7JHU1_CRIGR Isoform 1 of Vacuolar protein sorting-associated protein 33B OS=Cricetulus griseus OX=10029 GN=Vps33b PE=3 SV=1 CANONICAL=A0A9J7JHU1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JKH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU1/entry#A0A9J7JKH4-1", "sequence": { "sequence": "MAFPHRLDAPELPDFSMLKRLARDQLIYLLEQFYACEMVLEEEGVYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRCAKMSYDLWRKLEEEEDSETKGRRPEIGHIFLLDRDMDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFNEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQAPGDTLTAVENKVSKLVTDKAADTRWNLAQISSPGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLERRSWQGLDEVVRLLNCSEFAFTDMAKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAITNSARLMEAMSEVKA", "length": 542, "header": "tr|A0A9J7JKH4-1|A0A9J7JKH4_CRIGR Computationally mapped isoform of Vacuolar protein sorting-associated protein 33B isoform X4 OS=Cricetulus griseus OX=10029 GN=Vps33b PE=3 SV=1 CANONICAL=A0A9J7JHU1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHU1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 4% of CDS bases frameshifts :: corrected 5 indels internal stop codons :: corrected 4 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027258752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258752" } ] }, { "annotation": "Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4#function" }, { "database": "UniProtKB", "id": "ARBA00002845", "url": "https://www.uniprot.org/uniprotkb/ARBA00002845#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113834362", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4", "locus": {} } ], "crossref": [ { "id": "cd03715", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03715", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06095", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06095", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113834362", "url": "https://www.ncbi.nlm.nih.gov/gene/113834362", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113834362", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113834362", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JGK4", "url": "https://www.orthodb.org/?gene=A0A9J7JGK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027258752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258752", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCPGVQRLFALGDVPGGQEEDQGRLVDLHGEELLVNSRSTARFAFLSFCCGDCFYRVCNRGRHGTDCEDPLTLTLDHWTDVKTRAYNLSVEVRKGPWWTFCSSKWPSFSVGWPSXGTFNLSVISAVKRIIFQATGGHPDQVPYIIMWQDLVQNPPPWMKPWTSGIGTGTVAVVARKVPPSDSTAPDPTAPPRIYPEIDDVSLLDHPPPPYPQPISHAAPQVPTDSQPASEIGPTAGTRSRRGCSPEGSGTGPDSTVALPLXAYGPAPAPGELVPLQYWPFSSADMYNWKTNHPSFSENPSGLTGLLESLMYSHQPTWDDCQQLLQVLFTTXERILLEARKNVPGPDGIPTNLPNLIDAAFPLVRPDWDYNSAEGRGRLTVYRRALVAGLKGVVRRPTNLXKVREILQGPVEPPSVFLERLMEAYRRYTSFDPSLEGQQAAVAMAFIGQLASDIKKKLQRLEGLQDYTLQDLVKEAEKVYHKRETEEEKQERKKKEAEERENWWDRRQERNLTKILAAVVGGERSERGQSGYLGNRARRPPGGQRLQLEKDQCAYCKEKGHWARVCPRKKQKGPKMLALEEDXGSRGSVPLPEPRVTLSVGGNPVNFLVDTGAEHSVLTKPLGQLGSKKTLVMGATVSKLYPWTTERSLEIGKSQVTHSFLVIPECPAPLLGRDLLTKLKAQVQFTPKGPEVTWGEAPTTCLVLSLEEEYRLHEPKTGVLPPKEWLTAFPEVWAEQTGMGLAKQIPPVIVELKAAATPVSVRQYPMTQGAKEGIRPHIQRLLQQGILIPCRSPWNTPLLPVCKPGTNDYRPVQDLREVNKXVQDIHPTVPNPYNLLSSLPPERSWYTVLDLKDAFFCLRLHPNSQPLFAFEWRDPEGGHTGQLTWTRLPQGFKNSLTLFDEAFHRDLVPFRARNPQISLLQYVDDLLLAAXTQELCLDGTRKLLKELGELGYQVSAKKAQLCRSEVPYLGYALREARRWLTEARKKTVMQIPTPTTPRQVREILGTAGFCRLWIPGFAMLVAPLYPLTKEKVPVTWTEEHQRAFDKIKTALLTAPTLTLPDLTKSFTLYVDERAGVACGVLTQALGPWKRPVAYLSKKLDPVTSGWPSCLKAIAAVALLVNDADKLTLGQHMTVIAPHALESIVRQPPDCWMTNAWMTHYQSLLLNDRITFAPPAILKPATLLPEVKDSTPVHRCTDVMAEETGTRKDLTDQPWPGVPNWYTDGSSFVVEGKRRAGAAVVDGKQVIWASSLPEGTSAQKGELLALTQALRLAEVKAINIYTDSRYAFAMAHIHGAIYRXRGLLTSAGRDVKNKEEILALLEAIHLPQKLAIVHCLGHQKGADPVTKGNQMTDLTAKQAAQGAAVLAEETGTPPEPNKSYHNKDMTHAGKAQMFSFSGLAKTKDGRIILPSKAGQDYVRRIHQLTHLGNEKLKQLIKGSKYYVLGLNTIIKEVIESCQACTLTNAAQPFKEPGKRMRGDRLGIYLEVDFTEIQPGKYGKKYLLVFIDSFSGWVEAFPTKSETAQMVTKKILEEILPRFGIPKALEVVKTQIWDQIKEAYTPGTTEVPHRFQVGDSVLVR", "length": 1577, "header": "tr|A0A9J7JGK4-1|A0A9J7JGK4_CRIGR Isoform 1 of Gag-Pol polyprotein OS=Cricetulus griseus OX=10029 GN=LOC113834362 PE=3 SV=1 CANONICAL=A0A9J7JGK4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JGK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4/entry#A0A9J7JGK4-1", "sequence": { "sequence": "MCPGVQRLFALGDVPGGQEEDQGRLVDLHGEELLVNSRSTARFAFLSFCCGDCFYRVCNRGRHGTDCEDPLTLTLDHWTDVKTRAYNLSVEVRKGPWWTFCSSKWPSFSVGWPSXGTFNLSVISAVKRIIFQATGGHPDQVPYIIMWQDLVQNPPPWMKPWTSGIGTGTVAVVARKVPPSDSTAPDPTAPPRIYPEIDDVSLLDHPPPPYPQPISHAAPQVPTDSQPASEIGPTAGTRSRRGCSPEGSGTGPDSTVALPLXAYGPAPAPGELVPLQYWPFSSADMYNWKTNHPSFSENPSGLTGLLESLMYSHQPTWDDCQQLLQVLFTTXERILLEARKNVPGPDGIPTNLPNLIDAAFPLVRPDWDYNSAEGRGRLTVYRRALVAGLKGVVRRPTNLXKVREILQGPVEPPSVFLERLMEAYRRYTSFDPSLEGQQAAVAMAFIGQLASDIKKKLQRLEGLQDYTLQDLVKEAEKVYHKRETEEEKQERKKKEAEERENWWDRRQERNLTKILAAVVGGERSERGQSGYLGNRARRPPGGQRLQLEKDQCAYCKEKGHWARVCPRKKQKGPKMLALEEDXGSRGSVPLPEPRVTLSVGGNPVNFLVDTGAEHSVLTKPLGQLGSKKTLVMGATVSKLYPWTTERSLEIGKSQVTHSFLVIPECPAPLLGRDLLTKLKAQVQFTPKGPEVTWGEAPTTCLVLSLEEEYRLHEPKTGVLPPKEWLTAFPEVWAEQTGMGLAKQIPPVIVELKAAATPVSVRQYPMTQGAKEGIRPHIQRLLQQGILIPCRSPWNTPLLPVCKPGTNDYRPVQDLREVNKXVQDIHPTVPNPYNLLSSLPPERSWYTVLDLKDAFFCLRLHPNSQPLFAFEWRDPEGGHTGQLTWTRLPQGFKNSLTLFDEAFHRDLVPFRARNPQISLLQYVDDLLLAAXTQELCLDGTRKLLKELGELGYQVSAKKAQLCRSEVPYLGYALREARRWLTEARKKTVMQIPTPTTPRQVREILGTAGFCRLWIPGFAMLVAPLYPLTKEKVPVTWTEEHQRAFDKIKTALLTAPTLTLPDLTKSFTLYVDERAGVACGVLTQALGPWKRPVAYLSKKLDPVTSGWPSCLKAIAAVALLVNDADKLTLGQHMTVIAPHALESIVRQPPDCWMTNAWMTHYQSLLLNDRITFAPPAILKPATLLPEVKDSTPVHRCTDVMAEETGTRKDLTDQPWPGVPNWYTDGSSFVVEGKRRAGAAVVDGKQVIWASSLPEGTSAQKGELLALTQALRLAEVKAINIYTDSRYAFAMAHIHGAIYRXRGLLTSAGRDVKNKEEILALLEAIHLPQKLAIVHCLGHQKGADPVTKGNQMTDLTAKQAAQGAAVLAEETGTPPEPNKSYHNKDMTHAGKAQMFSFSGLAKTKDGRIILPSKAGQDYVRRIHQLTHLGNEKLKQLIKGSKYYVLGLNTIIKEVIESCQACTLTNAAQPFKEPGKRMRGDRLGIYLEVDFTEIQPGKYGKKYLLVFIDSFSGWVEAFPTKSETAQMVTKKILEEILPRFGIPKALEVVKTQIWDQIKEAYTPGTTEVPHRFQVGDSVLVR", "length": 1577, "header": "tr|A0A9J7JGK4-1|A0A9J7JGK4_CRIGR Isoform 1 of Gag-Pol polyprotein OS=Cricetulus griseus OX=10029 GN=LOC113834362 PE=3 SV=1 CANONICAL=A0A9J7JGK4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 188, "start_aa": "Thr", "end_pos": 188, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr188", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 234, "start_aa": "Thr", "end_pos": 234, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr234", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113834362", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113834362", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 6, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "pmid": "" }, { "name": "virion assembly", "id": "GO:0019068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019068", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1375, "end_pos": 1377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JGK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGK4" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 1462, 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. 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CANONICAL=A0A9J7JGL2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 351, "start_aa": "Thr", "end_pos": 351, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr351", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757085", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757085", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JGN6", "url": "https://www.orthodb.org/?gene=A0A9J7JGN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23317:SF74", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23317:SF74", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262292", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M1E0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1E0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M1E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1E0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSISASGFPTLQLPQLYEPVEPVDFEGLVMTHLDSLDAELAQELGDLTDDDLHVAFTPKECRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSSEFCSFKKTGSRRDFHKTLQKQTFESETLECSEPAAQTGPRQLKVLCDVSEKGPLTTCDFDLRSLQPDERLENLLQLLSAEDFEKKKEEARKTNRPAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKVLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIADCAEPYMVIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNVSTLERESNDMETVVGRNSVGERRSLSQSRRPSERSLSLEENGVGSNFKTTTLATSIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGSLRLEVSSAPDVMNCCLTPEMLPVKPFPENRTRPHKEVLEFPIREVYVPHTVYRNLLYVYPQRLNFANKLASARNITIKIQFMCGEDPSNAMPVIFGKSSGPEFLQEVYTAITYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASGESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLPELHRDAPKSGGPAAIPDPRYHTYGRTSAAAVSSKLIQARVMSSSNPDLAGAHCAADEEVKNIMSSKIADRNCSRMSYYCSGNNDATGSTAAPRPVSKKHFHEELALQMVVSTGLVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKESEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQFHTGNAMQLWRGLSGSGLGTANALNCTLSAKLNTLPTLISMRLEFLRILCSHEHYLNLNLLFMNTDTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAVALDSEGDGISRVQRKAVSAIHSLLSSHDLDPRCLKPEVKVKIAALYLPLVGIILDALPQLYDFTVADARSGRSRASGSYEEQDVANGINQNVALAIAGNHFNLKTSGAMLSSLPYKQYSMLSADTTRHLMICFLWIMKNADQSLIRRWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRRRTPGNDRFTGLNENLRWRKEQTQWRQANEKMDKTKAELDQEALISGNLATEANLITLDMQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMALASLVGKAPDFNEEHLRRSLRTILAYSEEDTAMQTTPFPTQVEELLYNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAFDNIINKDHKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLTTMHAFPYIKTRIQVIQKEEFVLTPIEVAIEDMKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELRKNYNKLKDSLRPMIERKIPELYKPIFRIDSQKRDSFHRSSFRKCETQLSQGS", "length": 2127, "header": "tr|A0A9J7JGN6-1|A0A9J7JGN6_CRIGR Isoform 1 of Dedicator of cytokinesis protein 8 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dock8 PE=3 SV=1 CANONICAL=A0A9J7JGN6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M1E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6/entry#A0A8C2M1E0-1", "sequence": { "sequence": "MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSISASGFPTLQLPQLYEPVEPVDFEGLVMTHLDSLDAELAQELGDLTDDDLHVAFTPKECRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSSEFCSFKKTGSRRDFHKTLQKQTFESETLECSEPAAQTGPRQLKVLCDVSEKGPLTTCDFDLRSLQPDERLENLLQLLSAEDFEKKKEEARKTNRPAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKVLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIADCAEPYMVIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNVSTLERESNDMETVVGRNSVGERRSLSQSRRPSERSLSLEENGVGSNFKTTTLATSIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGSLRLEVSSAPDVMNCCLTPEMLPVKPFPENRTRPHKEVLEFPIREVYVPHTVYRNLLYVYPQRLNFANKLASARNITIKIQFMCGEDPSNAMPVIFGKSSGPEFLQEVYTAITYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASGESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLPELHRDAPKSGGPAAIPDPRYHTYGRTSAAAVSSKLIQARVMSSSNPDLAGAHCAADEEVKNIMSSKIADRNCSRMSYYCSGNNDATGSTAAPRPVSKKHFHEELALQMVVSTGLVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKESEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQLSAKLNTLPTLISMRLEFLRILCSHEHYLNLNLLFMNTDTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAVALDSEGDGISRVQRKAVSAIHSLLSSHDLDPRCLKPEVKVKIAALYLPLVGIILDALPQLYDFTVADARSGRSRASGSYEEQDVANGINQNVALAIAGNHFNLKTSGAMLSSLPYKQYSMLSADTTRHLMICFLWIMKNADQSLIRRWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRRRTPGNDRFTGLNENLRWRKEQTQWRQANEKMDKTKAELDQEALISGNLATEANLITLDMQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMALASLVGKAPDFNEEHLRRSLRTILAYSEEDTAMQTTPFPTQVEELLYNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAFDNIINKDHKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLTTMHAFPYIKTRIQVIQKEEFVLTPIEVAIEDMKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELRKNYNKLKDSLRPMIERKIPELYKPIFRIDSQKRDSFHRSSFRKCETQLSQGS", "length": 2100, "header": "tr|A0A8C2M1E0-1|A0A8C2M1E0_CRIGR Computationally mapped isoform of Dedicator of cytokinesis protein 8 isoform X3 OS=Cricetulus griseus OX=10029 GN=Dock8 PE=3 SV=1 CANONICAL=A0A9J7JGN6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JGN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6/entry#A0A9J7JGN6-1", "sequence": { "sequence": "MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSISASGFPTLQLPQLYEPVEPVDFEGLVMTHLDSLDAELAQELGDLTDDDLHVAFTPKECRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSSEFCSFKKTGSRRDFHKTLQKQTFESETLECSEPAAQTGPRQLKVLCDVSEKGPLTTCDFDLRSLQPDERLENLLQLLSAEDFEKKKEEARKTNRPAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKVLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIADCAEPYMVIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNVSTLERESNDMETVVGRNSVGERRSLSQSRRPSERSLSLEENGVGSNFKTTTLATSIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGSLRLEVSSAPDVMNCCLTPEMLPVKPFPENRTRPHKEVLEFPIREVYVPHTVYRNLLYVYPQRLNFANKLASARNITIKIQFMCGEDPSNAMPVIFGKSSGPEFLQEVYTAITYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASGESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLPELHRDAPKSGGPAAIPDPRYHTYGRTSAAAVSSKLIQARVMSSSNPDLAGAHCAADEEVKNIMSSKIADRNCSRMSYYCSGNNDATGSTAAPRPVSKKHFHEELALQMVVSTGLVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKESEQAEKINISLAFFLYDLLSLMDRGFVFNLIKHYCNQFHTGNAMQLWRGLSGSGLGTANALNCTLSAKLNTLPTLISMRLEFLRILCSHEHYLNLNLLFMNTDTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAVALDSEGDGISRVQRKAVSAIHSLLSSHDLDPRCLKPEVKVKIAALYLPLVGIILDALPQLYDFTVADARSGRSRASGSYEEQDVANGINQNVALAIAGNHFNLKTSGAMLSSLPYKQYSMLSADTTRHLMICFLWIMKNADQSLIRRWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRRRTPGNDRFTGLNENLRWRKEQTQWRQANEKMDKTKAELDQEALISGNLATEANLITLDMQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMALASLVGKAPDFNEEHLRRSLRTILAYSEEDTAMQTTPFPTQVEELLYNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAFDNIINKDHKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLTTMHAFPYIKTRIQVIQKEEFVLTPIEVAIEDMKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELRKNYNKLKDSLRPMIERKIPELYKPIFRIDSQKRDSFHRSSFRKCETQLSQGS", "length": 2127, "header": "tr|A0A9J7JGN6-1|A0A9J7JGN6_CRIGR Isoform 1 of Dedicator of cytokinesis protein 8 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dock8 PE=3 SV=1 CANONICAL=A0A9J7JGN6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757085", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757085", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of establishment of T cell polarity", "id": "GO:1903905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903905", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6" } ], "pmid": "" }, { "name": "positive regulation of T cell migration", "id": "GO:2000406", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000406", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6" } ], "pmid": "" }, { "name": "cellular response to chemokine", "id": "GO:1990869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990869", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cell leading edge", "id": "GO:0031252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031252", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6" } ], "pmid": "" }, { "name": "leading edge membrane", "id": "GO:0031256", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031256", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGN6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1048, "end_pos": 1050, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1102, "end_pos": 1104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1157, "end_pos": 1159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1722, "end_pos": 1724, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 622, "end_pos": 624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 696, "end_pos": 698, "annotation": "n_glycosylation_sequon" }, { "start_pos": 781, "end_pos": 783, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" }, { "start_pos": 930, "end_pos": 932, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JGN6", "database": 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"snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1048, "end_pos": 1050 }, { "start_pos": 1102, "end_pos": 1104 }, { "start_pos": 1157, "end_pos": 1159 }, { "start_pos": 1722, "end_pos": 1724 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 622, "end_pos": 624 }, { "start_pos": 696, "end_pos": 698 }, { "start_pos": 781, "end_pos": 783 }, { "start_pos": 815, "end_pos": 817 }, { "start_pos": 930, "end_pos": 932 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"https://www.ncbi.nlm.nih.gov/protein/XP_027262327" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262327" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGP6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cemip2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGP6", "locus": {} } ], "crossref": [ { "id": "cd13938", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13938", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759479", "url": "https://www.ncbi.nlm.nih.gov/gene/100759479", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759479", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759479", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JGP6", "url": "https://www.orthodb.org/?gene=A0A9J7JGP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15535", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15535", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15535:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15535:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10162", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10162", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262327", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JGP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIQ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYAAGSRGHSPAFLQPQNGNGHRSPGYVPGKVVPLRPPPPPKNPASAKLTSTNQEGPATFAFSPEEQQTPRENRKQKRHKNTFICFAITSFSFFVALAVILGISSKYAPDENCPDQNPRLRNWDPGQDSGKHVVIKEGDMFRLTSDATVNSIVIQDGGLLVFGDDKDGSRNITLRTRYILIQDGGALHIGAEKCRYRSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGAQRTSWTMLARTLHSSGLPFGSYAFEKDFSRGLNVRVIDQDTARVLEHEKFDTHEYHNESRRLQEFLRAQDPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIHGLGYRQAWALVGVIDGGSSSCNESVRNYENHSTGGKALAQGEFYTLDGQKFSVTAYSEWIEGISLSGFRVEIADGAKLHLLDDVSSWEAGNRIVVASTDYSMYQAEEFTLLPCPECSRFQVKVKETPQYLHVGEIIDGIDMRAEVGILTRNIVIHGEMEGSCYADNQCQFFDNDTFGGHVMIEKNFTSVHLSYVELKHMGQQHLGRYPVHFHLCGDVDSKGGYSPPTSVAGLSIHHSFSRCITVHGTNGLLIKDTIGFDALGHCFFLEDGVEQRNILFHNLGLLTKPGTLLPTDRNSSMCTIMRDGVFGNYVPVPTTDCMAVSTFWIAHPNNHLINNAAAGSQDAGIWYLFHKEPTGESSGMQLLEKPELTPLGIFYNNRVHSNFKAGLFVDKGVKTTNSSAADPREYLCLDNSARFRPHQDADPDKPRVAAVIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGKGLTFASDGSFPSDEGSSQEVSESLFVGESKNYGFQGGQNKYMGIGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTKSTFKKYVPTPDRYSSAIGFLMKNSWQTTPRNNVSLVKFGPQVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPNCVNVTRWNAVVCSGTYAQVYVQTWNTPNLSMIITRDEYPSHPMVLRGINQRAISPQYQPVVMLEKGYTIHWNGPAPRITFLYLVNFNKDDWIRVGLCYPSNTSFQVTFGFLQRQSGSLSRIEEYEPAQSMEELQKKPSSRKFYFDSGTGLLFLYLRAHSHRDGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYKKPSAVKRMPAMLTGLCQGCGTHQMVFSSDPHKSYLPVQFQSPSKAETQRGDPSVISVNGTDFTFRSAGVLILVVDACSVPFRLTEKKMFLAADVSQMEEYLKASIPPRSIVLLSTRGEIKQMNISDSLVLLGLVKPAHLYSKGSIVFLGFSGNFRPSWTKLFTSPAEQGLGVLEQYLPLQMEDYGCPRASSVHRRDLELLQQALKVL", "length": 1383, "header": "tr|A0A9J7JGP6-1|A0A9J7JGP6_CRIGR Isoform 1 of hyaluronoglucosaminidase OS=Cricetulus griseus OX=10029 GN=Cemip2 PE=3 SV=1 CANONICAL=A0A9J7JGP6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JGP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGP6/entry#A0A9J7JGP6-1", "sequence": { "sequence": "MYAAGSRGHSPAFLQPQNGNGHRSPGYVPGKVVPLRPPPPPKNPASAKLTSTNQEGPATFAFSPEEQQTPRENRKQKRHKNTFICFAITSFSFFVALAVILGISSKYAPDENCPDQNPRLRNWDPGQDSGKHVVIKEGDMFRLTSDATVNSIVIQDGGLLVFGDDKDGSRNITLRTRYILIQDGGALHIGAEKCRYRSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGAQRTSWTMLARTLHSSGLPFGSYAFEKDFSRGLNVRVIDQDTARVLEHEKFDTHEYHNESRRLQEFLRAQDPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIHGLGYRQAWALVGVIDGGSSSCNESVRNYENHSTGGKALAQGEFYTLDGQKFSVTAYSEWIEGISLSGFRVEIADGAKLHLLDDVSSWEAGNRIVVASTDYSMYQAEEFTLLPCPECSRFQVKVKETPQYLHVGEIIDGIDMRAEVGILTRNIVIHGEMEGSCYADNQCQFFDNDTFGGHVMIEKNFTSVHLSYVELKHMGQQHLGRYPVHFHLCGDVDSKGGYSPPTSVAGLSIHHSFSRCITVHGTNGLLIKDTIGFDALGHCFFLEDGVEQRNILFHNLGLLTKPGTLLPTDRNSSMCTIMRDGVFGNYVPVPTTDCMAVSTFWIAHPNNHLINNAAAGSQDAGIWYLFHKEPTGESSGMQLLEKPELTPLGIFYNNRVHSNFKAGLFVDKGVKTTNSSAADPREYLCLDNSARFRPHQDADPDKPRVAAVIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGKGLTFASDGSFPSDEGSSQEVSESLFVGESKNYGFQGGQNKYMGIGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTKSTFKKYVPTPDRYSSAIGFLMKNSWQTTPRNNVSLVKFGPQVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPNCVNVTRWNAVVCSGTYAQVYVQTWNTPNLSMIITRDEYPSHPMVLRGINQRAISPQYQPVVMLEKGYTIHWNGPAPRITFLYLVNFNKDDWIRVGLCYPSNTSFQVTFGFLQRQSGSLSRIEEYEPAQSMEELQKKPSSRKFYFDSGTGLLFLYLRAHSHRDGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYKKPSAVKRMPAMLTGLCQGCGTHQMVFSSDPHKSYLPVQFQSPSKAETQRGDPSVISVNGTDFTFRSAGVLILVVDACSVPFRLTEKKMFLAADVSQMEEYLKASIPPRSIVLLSTRGEIKQMNISDSLVLLGLVKPAHLYSKGSIVFLGFSGNFRPSWTKLFTSPAEQGLGVLEQYLPLQMEDYGCPRASSVHRRDLELLQQALKVL", "length": 1383, "header": "tr|A0A9J7JGP6-1|A0A9J7JGP6_CRIGR Isoform 1 of hyaluronoglucosaminidase OS=Cricetulus griseus OX=10029 GN=Cemip2 PE=3 SV=1 CANONICAL=A0A9J7JGP6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGP6/entry#A0A9J7JIQ3-1", "sequence": { "sequence": "MFRLTSDATVNSIVIQDGGLLVFGDDKDGSRNITLRTRYILIQDGGALHIGAEKCRYRSKATITLYGKSDEGESMPTFGKKFIGVEAGGTLELHGAQRTSWTMLARTLHSSGLPFGSYAFEKDFSRGLNVRVIDQDTARVLEHEKFDTHEYHNESRRLQEFLRAQDPGRIVAIAVGDSAVKSLLQGTIQMIQDRLGSKLIHGLGYRQAWALVGVIDGGSSSCNESVRNYENHSTGGKALAQGEFYTLDGQKFSVTAYSEWIEGISLSGFRVEIADGAKLHLLDDVSSWEAGNRIVVASTDYSMYQAEEFTLLPCPECSRFQVKVKETPQYLHVGEIIDGIDMRAEVGILTRNIVIHGEMEGSCYADNQCQFFDNDTFGGHVMIEKNFTSVHLSYVELKHMGQQHLGRYPVHFHLCGDVDSKGGYSPPTSVAGLSIHHSFSRCITVHGTNGLLIKDTIGFDALGHCFFLEDGVEQRNILFHNLGLLTKPGTLLPTDRNSSMCTIMRDGVFGNYVPVPTTDCMAVSTFWIAHPNNHLINNAAAGSQDAGIWYLFHKEPTGESSGMQLLEKPELTPLGIFYNNRVHSNFKAGLFVDKGVKTTNSSAADPREYLCLDNSARFRPHQDADPDKPRVAAVIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGKGLTFASDGSFPSDEGSSQEVSESLFVGESKNYGFQGGQNKYMGIGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTKSTFKKYVPTPDRYSSAIGFLMKNSWQTTPRNNVSLVKFGPQVSLNVFFGKPGPWFEDCELDGDKNSIFHDIDGSVTGYKDAYVGRMDNYLIRHPNCVNVTRWNAVVCSGTYAQVYVQTWNTPNLSMIITRDEYPSHPMVLRGINQRAISPQYQPVVMLEKGYTIHWNGPAPRITFLYLVNFNKDDWIRVGLCYPSNTSFQVTFGFLQRQSGSLSRIEEYEPAQSMEELQKKPSSRKFYFDSGTGLLFLYLRAHSHRDGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYKKPSAVKRMPAMLTGLCQGCGTHQMVFSSDPHKSYLPVQFQSPSKAETQRGDPSVISVNGTDFTFRSAGVLILVVDACSVPFRLTEKKMFLAADVSQMEEYLKASIPPRSIVLLSTRGEIKQMNISDSLVLLGLVKPAHLYSKGSIVFLGFSGNFRPSWTKLFTSPAEQGLGVLEQYLPLQMEDYGCPRASSVHRRDLELLQQALKVL", 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NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262431" } ] }, { "annotation": "Pore-forming protein involved in both innate and adaptive immunity. Plays a central role in antigen cross-presentation in dendritic cells by forming a pore in antigen-containing compartments, thereby promoting delivery of antigens for cross-presentation. Also involved in innate immune response following bacterial infection; shows antibacterial activity against a wide spectrum of Gram-positive, Gram-negative and acid-fast bacteria. Reduces the viability of the intracytosolic pathogen L.monocytogenes by inhibiting acidification of the phagocytic vacuole of host cells which restricts bacterial translocation from the vacuole to the cytosol. Required for the antibacterial activity of reactive oxygen species and nitric oxide.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGR8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR8#function" }, { "database": "UniProtKB", "id": "ARBA00045689", "url": "https://www.uniprot.org/uniprotkb/ARBA00045689#function" } ] }, { "annotation": "Pore-forming protein that plays a central role in antigen cross-presentation in dendritic cells by mediating delivery of antigens for cross-presentation. Dendritic cells bridge innate and adaptive immunity by capturing exogenous antigens on MHC class-I molecules and presenting them to naive CD8(+) T-cells. 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269143" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGS2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766369", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2", "locus": {} } ], "crossref": [ { "id": "A0A9J7JGS2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JGS2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100766369", "url": "https://www.ncbi.nlm.nih.gov/gene/100766369", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766369", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766369", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JGS2", "url": "https://www.orthodb.org/?gene=A0A9J7JGS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26452", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26452", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269143", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JGS2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKENHSLTEFILVGFSDHPVLNTLLFLVFFVIYLVTMVGNLGLVVLIYIEHRLHTPMYIFLGNLALMDSCCSCAITPKMLQNFFSVDRRISLYECMTQFYFLCFAETADCFLLAAMAYDRYVAICNPLQYHTMMSKKLSIQMSIATFIASNLHSMIQTSCLLRLNFCKSNRIDHFFCDILPLYRLSCIDPFINELMIYIFSMPIQVFTITTILVSYFCILFTIFKMKSKDGRGKAFSTCASHFLSVSIFYICLLTYIGPSKDGNKDIPVAVFYTVIIPLLNPFIYSLRNKEVLNAFKKVMKIYNILKKSSSSAAH", "length": 316, "header": "tr|A0A9J7JGS2-1|A0A9J7JGS2_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100766369 PE=3 SV=1 CANONICAL=A0A9J7JGS2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JGS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2/entry#A0A9J7JGS2-1", "sequence": { "sequence": "MTKENHSLTEFILVGFSDHPVLNTLLFLVFFVIYLVTMVGNLGLVVLIYIEHRLHTPMYIFLGNLALMDSCCSCAITPKMLQNFFSVDRRISLYECMTQFYFLCFAETADCFLLAAMAYDRYVAICNPLQYHTMMSKKLSIQMSIATFIASNLHSMIQTSCLLRLNFCKSNRIDHFFCDILPLYRLSCIDPFINELMIYIFSMPIQVFTITTILVSYFCILFTIFKMKSKDGRGKAFSTCASHFLSVSIFYICLLTYIGPSKDGNKDIPVAVFYTVIIPLLNPFIYSLRNKEVLNAFKKVMKIYNILKKSSSSAAH", "length": 316, "header": "tr|A0A9J7JGS2-1|A0A9J7JGS2_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100766369 PE=3 SV=1 CANONICAL=A0A9J7JGS2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGS2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGS2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766369", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766369", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGS2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGS2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGS2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JGS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGS2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { 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"id": "A0A9J7JGT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3" } ] }, { "name": "Rxfp2", "type": "synonym", "evidence": [ { "id": "XP_027269209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269209" } ] } ], "protein_names": [ { "name": "Relaxin receptor 2", "type": "recommended", "evidence": [ { "id": "A0A9J7JGT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 106", "type": "synonym", "evidence": [ { "id": "A0A9J7JGT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor affecting testicular descent", "type": "synonym", "evidence": [ { "id": "A0A9J7JGT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3/entry#names_and_taxonomy" } ] }, { "name": "Leucine-rich repeat-containing G-protein coupled receptor 8", "type": "synonym", "evidence": [ { "id": "A0A9J7JGT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3/entry#names_and_taxonomy" } ] }, { "name": "Relaxin family peptide receptor 2", "type": "synonym", "evidence": [ { "id": "A0A9J7JGT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3/entry#names_and_taxonomy" } ] }, { "name": "relaxin receptor 2", "type": "synonym", "evidence": [ { "id": "XP_027269209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269209" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 3% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269209" } ] }, { "annotation": "Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3#function" }, { "database": "UniProtKB", "id": "ARBA00057738", "url": "https://www.uniprot.org/uniprotkb/ARBA00057738#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rxfp2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3", "locus": {} } ], "crossref": [ { "id": "A0A9J7JGT3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JGT3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00112", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24372:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24372:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269209", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JGT3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGT3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGT3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVPGDREIHSSEFEEQEIRQMSQCYPDFVLADGSMVAPLCQKGYFPCGNLTKCLPRAFHCDGVDDCENGADEDNCGDTSGWATIFGTVHGNVNKVTLTQECFLSQYPQHCYCIENELECIKADLKAVPKVSSNVTLLSLKKNKIHRLPVKVFSKYTELEKIYLQHNCITHISRKAFFGLYNLQILYLSHNCITALRPGTFKDLHRLTWLILDDNPITSISPRSFTGLNSLFFLSMVSNQLEVLPERLCAQMPRLNWMDLANNEIKYLTNSTFLTCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNMITKLPARIFSDLHLLQKLNLSSNPLLYVHKNQFGSLKQLQSLDLERIEIPNINTGMFQPMKNLSHIYLKSFRYCSYVPHVRICMPSTDGISSSEDLLANSILRVSVWVIAFITSVGNFLVIAVRSLIKAENTTHAMSIKILCCADCLMGVYLFFVGIFDIKYRGQYQKYALLWMESVPCRLLGFLATLSTEVSVLLLTFLTLEKFLVIVFPFSNLHLGKRQTAVVLAGIWGVGFLIAAVPFTSEDYFGNFYGKNGVCFPLHYDQAEDFGSRGYSLGIFLGVNLLAFLIIVFSYVAMFCSIQKTALQTAEVRNHIGKEVAVANRFFFIVFSDAICWIPVFVVKILSLFQVEVPGTITSWIVVFFLPVNSALNPILYTLTTSFFKDKLKQLLHKHRRKSIFKVKKKSLSTSIVWTDDSSLKLGVLNRIALGDNIMKPVSP", "length": 750, "header": 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This record is derived from a genomic sequence (NW_003615826.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003513319", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513319" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGV0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGV0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Insl6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGV0", "locus": {} } ], "crossref": [ { "id": "A0A9J7JGV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JGV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100769626", "url": "https://www.ncbi.nlm.nih.gov/gene/100769626", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022353", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022353", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769626", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769626", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JGV0", "url": "https://www.orthodb.org/?gene=A0A9J7JGV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12004", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12004", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12004:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12004:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003513319", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513319", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JGV0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKQLCCSCLLWFGLLQAAFSWEEMENRPRKLCGKHLLSQIIKLCGQTDWTQFEIDEQTSLGHIPHQSSHPPKTLKPEQIPSSSAWRKFTHPVPASTSQEKVINTWEGQPVPDYQFENTNVVPENTRKFSSHDANPYPGVVKLQKKSTDKINTHSSLFGRKHPQREQRGFSDKCCLKGCTKEELAVACLPYVDFKTNNKRHW", "length": 201, "header": "tr|A0A9J7JGV0-1|A0A9J7JGV0_CRIGR Isoform 1 of Insulin-like peptide INSL6 OS=Cricetulus griseus OX=10029 GN=Insl6 PE=3 SV=1 CANONICAL=A0A9J7JGV0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JGV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGV0/entry#A0A9J7JGV0-1", "sequence": { "sequence": "MKQLCCSCLLWFGLLQAAFSWEEMENRPRKLCGKHLLSQIIKLCGQTDWTQFEIDEQTSLGHIPHQSSHPPKTLKPEQIPSSSAWRKFTHPVPASTSQEKVINTWEGQPVPDYQFENTNVVPENTRKFSSHDANPYPGVVKLQKKSTDKINTHSSLFGRKHPQREQRGFSDKCCLKGCTKEELAVACLPYVDFKTNNKRHW", "length": 201, "header": "tr|A0A9J7JGV0-1|A0A9J7JGV0_CRIGR Isoform 1 of Insulin-like peptide INSL6 OS=Cricetulus griseus OX=10029 GN=Insl6 PE=3 SV=1 CANONICAL=A0A9J7JGV0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGV0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGV0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGV0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGV0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769626", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769626", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGV0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hormone activity", "id": "GO:0005179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005179", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGV0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JGV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGV0" }, { "id": "SM00078", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00078" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Insulin-like", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 187, "start_aa": "Arg", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JGW8-1", "uniprot_ac": "A0A9J7JGW8", "uniprot_id": "A0A9J7JGW8_CRIGR", "mass": { "chemical_mass": 29065.0, "monoisotopic_mass": 29065.0 }, "refseq": { "ac": "XP_007644954", "name": "transcription initiation factor TFIID subunit 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644954" }, "gene_names": [ { "name": "Taf9", "type": "recommended", "evidence": [ { "id": "A0A9J7JGW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGW8" } ] }, { "name": "Taf9", "type": "synonym", "evidence": [ { "id": "XP_007644954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644954" } ] } ], "protein_names": [ { "name": "Transcription initiation factor TFIID subunit 9", "type": "synonym", "evidence": [ { "id": "A0A9J7JGW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGW8/entry#names_and_taxonomy" } ] }, { "name": "transcription initiation factor TFIID subunit 9", "type": "synonym", "evidence": [ { "id": "XP_007644954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644954" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614223.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644954" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGW8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Taf9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGW8", "locus": {} } ], "crossref": [ { "id": "A0A9J7JGW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JGW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07979", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07979", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103158543", "url": "https://www.ncbi.nlm.nih.gov/gene/103158543", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103158543", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158543", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IRHNSDH", "url": "https://omabrowser.org/oma/group/IRHNSDH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JGW8", "url": "https://www.orthodb.org/?gene=A0A9J7JGW8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48068:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48068:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02291", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02291", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644954", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JGW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESGKMASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKASTPAGRITVPRLSVGSVSSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPASQSPAVKASIPATSAVQNVLINPSLIGSKNILITTNMVSQNTANESANALKRKREDDDDDDDDDDDDDYDNL", "length": 265, "header": "tr|A0A9J7JGW8-1|A0A9J7JGW8_CRIGR Isoform 1 of Transcription initiation factor TFIID subunit 9 OS=Cricetulus griseus OX=10029 GN=Taf9 PE=3 SV=1 CANONICAL=A0A9J7JGW8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JGW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGW8/entry#A0A9J7JGW8-1", "sequence": { "sequence": "MESGKMASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKASTPAGRITVPRLSVGSVSSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPASQSPAVKASIPATSAVQNVLINPSLIGSKNILITTNMVSQNTANESANALKRKREDDDDDDDDDDDDDYDNL", "length": 265, "header": "tr|A0A9J7JGW8-1|A0A9J7JGW8_CRIGR Isoform 1 of Transcription initiation factor TFIID subunit 9 OS=Cricetulus griseus OX=10029 GN=Taf9 PE=3 SV=1 CANONICAL=A0A9J7JGW8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGW8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGW8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103158543", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158543", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AFL9-1", "protein_name": "TATA-box binding protein associated factor 9", "gene_name": "TAF9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESGKMASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKASTSAGRITVPRLSVGSVTSRPSTPTLGTPTQQTMSVPAKVGTPVSLTGQRFTVQMPTSQSPAVKASIPATSAVQNVLINPSLIGSKNILITTNMVSSQNTASESSNALKRKREDDDDDEDDDDDDYDNL", "length": 265 }, "evidence": [ { "id": "A0A9J7JGW8", "url": "https://omabrowser.org/oma/group/A0A9J7JGW8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q16594-1", "protein_name": "Transcription initiation factor TFIID subunit 9", "gene_name": "TAF9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESGKTASPKSMPKDAQMMAQILKDMGITEYEPRVINQMLEFAFRYVTTILDDAKIYSSHAKKATVDADDVRLAIQCRADQSFTSPPPRDFLLDIARQRNQTPLPLIKPYSGPRLPPDRYCLTAPNYRLKSLQKKASTSAGRITVPRLSVGSVTSRPSTPTLGTPTPQTMSVSTKVGTPMSLTGQRFTVQMPTSQSPAVKASIPATSAVQNVLINPSLIGSKNILITTNMMSSQNTANESSNALKRKREDDDDDDDDDDDYDNL", "length": 264 }, "evidence": [ { "id": "A0A9J7JGW8", "url": "https://omabrowser.org/oma/group/A0A9J7JGW8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q17QQ4-1", "protein_name": "Transcription initiation factor TFIID subunit 9", "gene_name": "TAF9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262629" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753369", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX5", "locus": {} } ], "crossref": [ { "id": "A0A9J7JGX5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JGX5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15407", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15407", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753369", "url": "https://www.ncbi.nlm.nih.gov/gene/100753369", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753369", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753369", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JGX5", "url": "https://www.orthodb.org/?gene=A0A9J7JGX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262629", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262629", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JGX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JGX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLMKNRTEVTHFLLLGLTDEPGLQIPLFITFLLIYTITLVGNLGMILLIVLDSRLHTPMYFFLGNLSLVDFCYSSAVTPTVMTGLLIGDKVISYNDCATQMFFFVAFATVESYLLASMAYDRYTAVCKPLYYATTMTRSVYVCLSIGSYFCGFLNASIHTGDTFSLSFCGPNIVHHFFCDLPAVMVLSCSDRHVSDLVLVYVVSFNIFFALLVIWISYILIFVTILKMKSSAGYQKAVSTCASHFTAVSIFYGTSIFMYLQPSSSHSMDTDKIASVFYTMIIPMLNPLVYSLRNKEVKGAFKKIVLEANSS", "length": 312, "header": "tr|A0A9J7JGX5-1|A0A9J7JGX5_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100753369 PE=3 SV=1 CANONICAL=A0A9J7JGX5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JGX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGX5/entry#A0A9J7JGX5-1", "sequence": { "sequence": "MTLMKNRTEVTHFLLLGLTDEPGLQIPLFITFLLIYTITLVGNLGMILLIVLDSRLHTPMYFFLGNLSLVDFCYSSAVTPTVMTGLLIGDKVISYNDCATQMFFFVAFATVESYLLASMAYDRYTAVCKPLYYATTMTRSVYVCLSIGSYFCGFLNASIHTGDTFSLSFCGPNIVHHFFCDLPAVMVLSCSDRHVSDLVLVYVVSFNIFFALLVIWISYILIFVTILKMKSSAGYQKAVSTCASHFTAVSIFYGTSIFMYLQPSSSHSMDTDKIASVFYTMIIPMLNPLVYSLRNKEVKGAFKKIVLEANSS", "length": 312, "header": "tr|A0A9J7JGX5-1|A0A9J7JGX5_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100753369 PE=3 SV=1 CANONICAL=A0A9J7JGX5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 79, "start_aa": "Thr", "end_pos": 79, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr79", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"header": "tr|A0A9J7JGZ9-1|A0A9J7JGZ9_CRIGR Isoform 1 of LOW QUALITY PROTEIN: junction-mediating and -regulatory protein isoform X2 OS=Cricetulus griseus OX=10029 GN=Jmy PE=4 SV=1 CANONICAL=A0A9J7JGZ9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 158, "start_aa": "Thr", "end_pos": 158, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr158", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", 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"glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGZ9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGZ9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761093", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761093", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "'de novo' actin filament nucleation", "id": "GO:0070060", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070060", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JGZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGZ9" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14519:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14519:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JH08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH08-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPI6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALVLMTSSIVSVLGSLYLAYILYFVLKEFCIICVTTYVLNFILLIINYKRLVYLNEAWKRQLQPKED", "length": 176, "header": "tr|A0A9J7JH08-1|A0A9J7JH08_CRIGR Isoform 1 of vitamin-K-epoxide reductase (warfarin-sensitive) OS=Cricetulus griseus OX=10029 GN=Vkorc1l1 PE=3 SV=1 CANONICAL=A0A9J7JH08-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JH08-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08/entry#A0A9J7JH08-1", "sequence": { "sequence": "MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALVLMTSSIVSVLGSLYLAYILYFVLKEFCIICVTTYVLNFILLIINYKRLVYLNEAWKRQLQPKED", "length": 176, "header": "tr|A0A9J7JH08-1|A0A9J7JH08_CRIGR Isoform 1 of vitamin-K-epoxide reductase (warfarin-sensitive) OS=Cricetulus griseus OX=10029 GN=Vkorc1l1 PE=3 SV=1 CANONICAL=A0A9J7JH08-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08/entry#A0A9J7JNK8-1", "sequence": { "sequence": "MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSAALASRHDGQCSCSSCPHDLLHRVCFGVFVPGLHSVLCAEGVLHHLRHHICAELHSPHHQLQTTSLLE", "length": 127, "header": "tr|A0A9J7JNK8-1|A0A9J7JNK8_CRIGR Computationally mapped isoform of Vitamin K epoxide reductase complex subunit 1-like protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Vkorc1l1 PE=4 SV=1 CANONICAL=A0A9J7JH08-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08/entry#A0A9J7JPI6-1", "sequence": { "sequence": "MAAPVLLRVSVPRWERVARWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALVLMTSSIVSVLGSLYLAYILYFVLKEFCIICVTTYVLNFILLIINYKRLVYLNEAWKRQLQPKED", "length": 130, "header": "tr|A0A9J7JPI6-1|A0A9J7JPI6_CRIGR Computationally mapped isoform of vitamin-K-epoxide reductase (warfarin-sensitive) OS=Cricetulus griseus OX=10029 GN=Vkorc1l1 PE=3 SV=1 CANONICAL=A0A9J7JH08-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757934", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757934", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "vitamin-K-epoxide reductase (warfarin-sensitive) activity", "id": "GO:0047057", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047057", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08" } ], "pmid": "" }, { "name": "quinone binding", "id": "GO:0048038", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048038", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vitamin K metabolic process", "id": "GO:0042373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042373", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH08", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JH08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH08" }, { "id": "SM00756", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00756" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Vitamin K epoxide reductase", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 160, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.17.4.4", "ec_name": "phylloquinol + [protein]-disulfide = phylloquinone + [protein]-dithiol.", "evidence": [ { "id": "1.17.4.4", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.17.4.4" }, { "id": "1.17.4.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.17.4.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JH30-1", "uniprot_ac": "A0A9J7JH30", "uniprot_id": "A0A9J7JH30_CRIGR", "mass": { "chemical_mass": 71942.0, "monoisotopic_mass": 71942.0 }, "refseq": { "ac": "XP_027257652", "name": "RNA polymerase II elongation factor ELL2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257652" }, "gene_names": [ { "name": "Ell2", "type": "recommended", "evidence": [ { "id": "A0A9J7JH30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH30" } ] }, { "name": "Ell2", "type": "synonym", "evidence": [ { "id": "XP_027257652", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257652" } ] } ], "protein_names": [ { "name": "RNA polymerase II elongation factor ELL2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027257652", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257652" }, { "id": "A0A9J7JH30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH30/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027257652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257652" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH30", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH30" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ell2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH30", "locus": {} } ], "crossref": [ { "id": "A0A9J7JH30", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JH30", "database": "AlphaFoldDB", "categories": [] }, { "id": "100762315", "url": "https://www.ncbi.nlm.nih.gov/gene/100762315", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031176", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031176", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762315", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762315", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JH30", "url": "https://www.orthodb.org/?gene=A0A9J7JH30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23288:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23288:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07303", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07303", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027257652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257652", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JH30", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH30-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGGAAGLREEQRYGLACGRLGQDNITVLHVKLTETAIRALETYQSHKNLIPFRPSIQFQGLQGLVKIPKNDPLSEVHNFNFYLSNVGKDNPQGSFDCIQQTLSSSGASQLNCLGFIQDKITVCATNDSYQMTRERMTQAEEESRNRSTKVIKPGGPYVGKRVQIRKAPQAISDAVPERKRSTPMNPANTIRKTHGGSSVSQRPYRDRVIHLLALKAYKKPELLARLQKDGVNQKDKNSLGAILQQVANLNPKDLSYTLKDYVFKELQRDWPGYSETDRRSLESVLSRKLNPSQNAGTSRSESPMCSSKDSASSPQKRPLDSDFIDPLMNKKARISHLTNRVPPTLNGHLNPTNEKSPAGLLPPPAAAAIPTPSPLPSTHLPVSNPPQTVNSNSNSPSTPEGRGTQDLPIDSFSPNGSIFEDQQDKYTSRTCLETLPPGSVLLKCPKPMEENHPVSHKKSKKKSKKHKEKDQIKKHDIETVEEKEEDLQREETAKLRNSSPNPSEGVKEGCTASMEPSSTIELPDYLVKYIAIVSYEQRQNYKDDFNAEYDEYRALHARMETVARRFIKLDAQRKRLSPGSKEYQNVHEEVLQEYQKIKQSSPNYHEEKYRCEYLHNKLAHIKRLIGEFDQQQAESWH", "length": 639, "header": "tr|A0A9J7JH30-1|A0A9J7JH30_CRIGR Isoform 1 of RNA polymerase II elongation factor ELL2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ell2 PE=3 SV=1 CANONICAL=A0A9J7JH30-1" }, "isoforms": [ { 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PE=4 SV=1 CANONICAL=A0A9J7JH37-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"mass": { "chemical_mass": 169274.0, "monoisotopic_mass": 169274.0 }, "refseq": { "ac": "XP_027269925", "name": "LOW QUALITY PROTEIN: uncharacterized protein LOC113835489", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269925" }, "gene_names": [ { "name": "LOC113835489", "type": "recommended", "evidence": [ { "id": "A0A9J7JH72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ] }, { "name": "LOC113835489", "type": "synonym", "evidence": [ { "id": "XP_027269925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269925" } ] } ], "protein_names": [ { "name": "Gag-Pol polyprotein", "type": "recommended", "evidence": [ { "id": "A0A9J7JH72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72/entry#names_and_taxonomy" } ] }, { "name": "2.7.7.49", "type": "synonym", "evidence": [ { "id": "A0A9J7JH72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72/entry#names_and_taxonomy" } ] }, { "name": "3.1.26.4", "type": "synonym", "evidence": [ { "id": "A0A9J7JH72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: uncharacterized protein LOC113835489", "type": "synonym", "evidence": [ { "id": "XP_027269925", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269925" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 3 indels internal stop codons :: corrected 4 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027269925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269925" } ] }, { "annotation": "Forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72#function" }, { "database": "UniProtKB", "id": "ARBA00002845", "url": "https://www.uniprot.org/uniprotkb/ARBA00002845#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113835489", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72", "locus": {} } ], "crossref": [ { "id": "cd03715", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03715", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06095", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06095", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113835489", "url": "https://www.ncbi.nlm.nih.gov/gene/113835489", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000477", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000477", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000840", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000840", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010999", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010999", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015416", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015416", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113835489", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113835489", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JH72", "url": "https://www.orthodb.org/?gene=A0A9J7JH72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00665", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00665", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17919", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027269925", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269925", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH72-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQTVTTPLTLTLDHXTDVKTRAHNLSVEVRKGPWRTFCSSEWPSFGVGWPSGRTFNLAIISAVKRIIFQATGGHPDQVPYIIVWQDLVQNPPPWMKPWTLGIGTATVAVATRKVPPSDSLEPAPTAPPRIYPEIDDVSLLDHPPPPYPQPAPHAAPQAPTDSQTASEIGPAAGTRSRRGRSPEGSGAGPDSAIALPLWAYGPAPAPGELVPLQYWPFSSADMYNWKTNHPSFSENPSGLTGLLESLMYSHQPTWDDCQQLLQVLFTTEERERILLEARKNVAGPDGTPTNLPNLIDAAFPLVRPDCDYNSAEGRGRLTVYRQALVAGLKGAARRPINLAKVREILQGPVEPPSVFLERLMEAYRRYTPFDPSSEGQQAAVAMAFIGQSASDIKKKLQRLEGLQDYTLQDLVKEAEKVYHKRETEEEKQERKKKEAEERENRLDRHQERNLTKILAAVVGGERSERGQSGYLGNRARRPPGGQRLQLEKDQCAYCKEKGHWARDXPRKKQKGPKMLALEEDXGSWGSVPLPEPRVTLSVEGNPVNFLVDTGVEHSVLTKPLGQLGSKKTLLIGATGSKLYPWTTERSLKIGKSQVTHSFLVIPECPAPLLGRDLLTKLKAQVQFTPKGPEVTWGEAPITCLVLSLEEEYRLHEPKTGGLPPKEWLTAFPEVWAEQTEMGLAKQVPPVVVELKAAATPVSVRQYPMTQGAKEGIRPHIQRLLQQGILIPCRSPWNTSFLPVCKPGTNDYRPVQVLREVKKPVQDIHPTVPNPYNLLSSLPPERSWYTVLDLKDAFFCLRLHPNSQPLFAFEWRDPEGGHTGQLTWTRLPQGFKNSPTLFDEVLHRDLVPFRARNPQISLLQNVDDLLLAASTQELCLDGTRKLLKELGELGYRVSAKKAQLCRSEVTYLGYTLREXRWLTEAWKKTVMQILTPTTPRQVCEFLGTASFCRLWIPGFTMLAAPLYPLTKEKVPFTWTKEHQRVFDKIKTALLTAPELTLPDLTKLFTLYVDEQAGVARGVLTQTLGPWKRPVAYLSKKLDPVASRWPSCLKAIAAVALLVKDDDNLTVGQHVTVIAPHALESIVWQPPDRWMTNARMTHYQSLLLNDQITFAPPAILNPATLLPEAEDSTPVHRCTDVLAEETGTRKDLTDQPWPGVPNWYTDGSSFVVKGKRRAGAAVVDGKQVIWASSLPEGTSAQKAELLALTQALRLAEGKAINIYTDSRYAFATAHIHGAIYRQRGLLTSAGRDVKNKEEILALLEAIHLPQKLAIVHCLGHQKGTDPVTKGNQMADLTAKQAAQGAVVLAEETGTLPEPPQASFIHPSFIYPYKDYDLIEDMTRAGKARMFSFGGLAKTKDGQIILPSKEGQDYVRXIHQLTHLGNKKLKQLIKGSKYYVLGLNTIIKEVIESCQAWTLTNAARSFKEPGKRMRGDRPGIYWEVDFTEIKPGKYGNKYLLVFIDTFSGWVEAFHTKSETAQMVTKKILEEILPRFGIPKALEVVKTQIWDQIKEAYTPGTTEVPH", "length": 1519, "header": "tr|A0A9J7JH72-1|A0A9J7JH72_CRIGR Isoform 1 of Gag-Pol polyprotein OS=Cricetulus griseus OX=10029 GN=LOC113835489 PE=3 SV=1 CANONICAL=A0A9J7JH72-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JH72-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72/entry#A0A9J7JH72-1", "sequence": { "sequence": "MGQTVTTPLTLTLDHXTDVKTRAHNLSVEVRKGPWRTFCSSEWPSFGVGWPSGRTFNLAIISAVKRIIFQATGGHPDQVPYIIVWQDLVQNPPPWMKPWTLGIGTATVAVATRKVPPSDSLEPAPTAPPRIYPEIDDVSLLDHPPPPYPQPAPHAAPQAPTDSQTASEIGPAAGTRSRRGRSPEGSGAGPDSAIALPLWAYGPAPAPGELVPLQYWPFSSADMYNWKTNHPSFSENPSGLTGLLESLMYSHQPTWDDCQQLLQVLFTTEERERILLEARKNVAGPDGTPTNLPNLIDAAFPLVRPDCDYNSAEGRGRLTVYRQALVAGLKGAARRPINLAKVREILQGPVEPPSVFLERLMEAYRRYTPFDPSSEGQQAAVAMAFIGQSASDIKKKLQRLEGLQDYTLQDLVKEAEKVYHKRETEEEKQERKKKEAEERENRLDRHQERNLTKILAAVVGGERSERGQSGYLGNRARRPPGGQRLQLEKDQCAYCKEKGHWARDXPRKKQKGPKMLALEEDXGSWGSVPLPEPRVTLSVEGNPVNFLVDTGVEHSVLTKPLGQLGSKKTLLIGATGSKLYPWTTERSLKIGKSQVTHSFLVIPECPAPLLGRDLLTKLKAQVQFTPKGPEVTWGEAPITCLVLSLEEEYRLHEPKTGGLPPKEWLTAFPEVWAEQTEMGLAKQVPPVVVELKAAATPVSVRQYPMTQGAKEGIRPHIQRLLQQGILIPCRSPWNTSFLPVCKPGTNDYRPVQVLREVKKPVQDIHPTVPNPYNLLSSLPPERSWYTVLDLKDAFFCLRLHPNSQPLFAFEWRDPEGGHTGQLTWTRLPQGFKNSPTLFDEVLHRDLVPFRARNPQISLLQNVDDLLLAASTQELCLDGTRKLLKELGELGYRVSAKKAQLCRSEVTYLGYTLREXRWLTEAWKKTVMQILTPTTPRQVCEFLGTASFCRLWIPGFTMLAAPLYPLTKEKVPFTWTKEHQRVFDKIKTALLTAPELTLPDLTKLFTLYVDEQAGVARGVLTQTLGPWKRPVAYLSKKLDPVASRWPSCLKAIAAVALLVKDDDNLTVGQHVTVIAPHALESIVWQPPDRWMTNARMTHYQSLLLNDQITFAPPAILNPATLLPEAEDSTPVHRCTDVLAEETGTRKDLTDQPWPGVPNWYTDGSSFVVKGKRRAGAAVVDGKQVIWASSLPEGTSAQKAELLALTQALRLAEGKAINIYTDSRYAFATAHIHGAIYRQRGLLTSAGRDVKNKEEILALLEAIHLPQKLAIVHCLGHQKGTDPVTKGNQMADLTAKQAAQGAVVLAEETGTLPEPPQASFIHPSFIYPYKDYDLIEDMTRAGKARMFSFGGLAKTKDGQIILPSKEGQDYVRXIHQLTHLGNKKLKQLIKGSKYYVLGLNTIIKEVIESCQAWTLTNAARSFKEPGKRMRGDRPGIYWEVDFTEIKPGKYGNKYLLVFIDTFSGWVEAFHTKSETAQMVTKKILEEILPRFGIPKALEVVKTQIWDQIKEAYTPGTTEVPH", "length": 1519, "header": "tr|A0A9J7JH72-1|A0A9J7JH72_CRIGR Isoform 1 of Gag-Pol polyprotein OS=Cricetulus griseus OX=10029 GN=LOC113835489 PE=3 SV=1 CANONICAL=A0A9J7JH72-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 126, "start_aa": "Thr", "end_pos": 126, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr126", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113835489", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113835489", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA-directed DNA polymerase activity", "id": "GO:0003964", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003964", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "pmid": "" }, { "name": "aspartic-type endopeptidase activity", "id": "GO:0004190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004190", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "DNA recombination", "id": "GO:0006310", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006310", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "pmid": "" }, { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "pmid": "" }, { "name": "virion assembly", "id": "GO:0019068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019068", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "pmid": "" }, { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH72", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1063, "end_pos": 1065, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JH72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 1428, "end_pos": 1519, "start_aa": "Arg", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JH72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" }, { "id": "PS50175", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50175" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase A2", "eco_id": "ECO_0000259", "start_pos": 544, "end_pos": 614, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JH72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" }, { "id": "PS50879", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50879" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNase H type-1", "eco_id": "ECO_0000259", "start_pos": 1152, "end_pos": 1298, "start_aa": "Trp", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JH72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH72" }, { "id": "PS50878", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50878" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reverse transcriptase", "eco_id": "ECO_0000259", "start_pos": 721, "end_pos": 912, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.26.4", "ec_name": "Endonucleolytic cleavage to 5'-phosphomonoester.", "evidence": [ { "id": "3.1.26.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.26.4" } ] }, { "ec_number": "2.7.7.49", "ec_name": "DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate.", "evidence": [ { "id": "2.7.7.49", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.7.49" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 126 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1063, "end_pos": 1065 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 734, "end_pos": 736 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JH75-1", "uniprot_ac": "A0A9J7JH75", "uniprot_id": "A0A9J7JH75_CRIGR", "mass": { "chemical_mass": 173482.0, "monoisotopic_mass": 173482.0 }, "refseq": { "ac": "XP_027240278", "name": "canalicular multispecific organic anion transporter 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240278" }, "gene_names": [ { "name": "Abcc2", "type": "recommended", "evidence": [ { "id": "A0A9J7JH75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75" } ] }, { "name": "Abcc2", "type": "synonym", "evidence": [ { "id": "XP_027240278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240278" } ] } ], "protein_names": [ { "name": "Canalicular multispecific organic anion transporter 1", "type": "synonym", "evidence": [ { "id": "A0A9J7JH75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75/entry#names_and_taxonomy" } ] }, { "name": "canalicular multispecific organic anion transporter 1", "type": "synonym", "evidence": [ { "id": "XP_027240278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240278" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615438.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027240278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240278" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Abcc2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75", "locus": {} } ], "crossref": [ { "id": "cd03244", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03244", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03250", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03250", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18595", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18595", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18603", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18603", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100689220", "url": "https://www.ncbi.nlm.nih.gov/gene/100689220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005292", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005292", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056227", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056227", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100689220", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100689220", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RRRYILW", "url": "https://omabrowser.org/oma/group/RRRYILW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JH75", "url": "https://www.orthodb.org/?gene=A0A9J7JH75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24223:SF176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24223:SF176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027240278", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240278", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19121", "url": "https://www.rhea-db.org/rhea/19121", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "38963", "url": "https://www.rhea-db.org/rhea/38963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "60128", "url": "https://www.rhea-db.org/rhea/60128", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JH75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JH75-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1544, "header": "tr|A0A9J7JH75-1|A0A9J7JH75_CRIGR Isoform 1 of Canalicular multispecific organic anion transporter 1 OS=Cricetulus griseus OX=10029 GN=Abcc2 PE=3 SV=1 CANONICAL=A0A9J7JH75-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JH75-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75/entry#A0A9J7JH75-1", "sequence": { "sequence": "MEEFCNSTFWNSSFLERQEADLPLCFEQTVLVWIPLGFLWLLAPWQLFSVYRSKTKKSSITKFYIAKQVLVVLLLIVAAIDLALALTEDSGQDTIPPVRYTNPILYICTWLLVLVIQHSRQRCIQKNSWFLSIFWVLSILCSTFQFQTLIRVLLQDSKSNLAYSCLFFVSYGFQIIILILSTLSEKSDPSHNPSSTASFLSSITFSWYDSIVLKGYKHPLTLDDIWDVDEGFKTKSIASKFEEFMTKDLQKAKQAFQRRRQKKLQQNPEATLHGLNKNQSQSQDVLVLEEAKKKKKKSGTTKDFPKSWLIKSLFKTFHVVILKSFILKLIHDILMFLSPQLLKFLIAFVSNPDTYTWLGYVSAILIFVVTLIQSFCLQYYFQFCFVLGMTVRTTVLSSVYKKALSLSNLARRQYTIGETVNLMSVDAQKLVEVTNYMHLVWSSVLQIALSIFFLWRELGPSVLAGVGVMVLLIPVNGVLATKNRKIQVQNMKYKDKRLKIMNEILSGIKILKYFAWEPSFRDQVYGLRKKELKNLLKYGQLQTVMIFLLQLTPILVSVITFTVYVLVDSNNILDAEKAFTSITLFNVLRFPLTMLPMVTSSILQASVSIDRIEKYLGGDDLDTSSIHHVGNFDKAVQFSEASFTWDPDMDPAIRDVSLDIKPGQLVAVVGTVGSGKSSLIAAMLGEMETVHGHITIKGTTAYVPQQSWIQNGTIKDNIIFGSEFNENKYQQVLEACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARATYQDSDIYILDDPLSAVDAHVGKHIFNKVIGPNGLLNGKTRILVTHSIHFLPQVDEIIVLGNGTVLEKGSYQNLLSKKGVFAKNLKTFVKHSGPEGEATVNDDSEEDDDDCGLIPTVEEIPEDAASLTMKRENSLRRTLSRSSRSSGRHVKSLKDSLRVKNANALKEKEELVKGQKLIKKEFVETGKVKFSIYLKYLQSVGWWSIAFVIFSYGLNSVAFIGSNLWLSAWTSDSQNFNSTNYPTSQRDMRIGVFGALGLAQGVFVFIASIWSVYACNYSSKTLHKQLLTNILRAPMSFFDTTPTGRIVNRFSGDISTVDDILPQTLRSWLMCFFGIISTLVMICMATPIFAVIIIPLAIIYVSVQVFYVATSRQLRRLDSVTRSPIYSHFSETVSGLPVIRAFEHQQRFLSRSEGLIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYKNSLTGDTVGFVLSNALNITQTLNWLVRMTSEAETNIVAVERINEYINVENEAPWVTDKRPPADWPSKGEIRFNNYQVRYRPELDLVLKGITCHIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGVDIASVGLHDLRGKLTIIPQDPILFSGSLRMNLDPFNKYSDEEVWKALELAHLKSFVDGLQLGLYHEVTEGGDNLSIGQRQLLCLGRALLLKSKILILDEATAAVDLGTDSLIQTTIRNEFSNCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELMSKTGPFYLMAKEAGIETANNTEL", "length": 1544, "header": "tr|A0A9J7JH75-1|A0A9J7JH75_CRIGR Isoform 1 of Canalicular multispecific organic anion transporter 1 OS=Cricetulus griseus OX=10029 GN=Abcc2 PE=3 SV=1 CANONICAL=A0A9J7JH75-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100689220", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100689220", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1NLJ8-1", "protein_name": "Multidrug resistance-associated protein 1", "gene_name": "ABCC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLDTYCNSTFWNSSLLDSPEVDLPLCFEQTVLVWIPLGFLWLLAPWQLLHVYRSRTKKSSITKLYLAKQVIVGFLLILAAIDLALALTEGTGQAAVPAVRYTNPILYLVTWVLVLLIQHSRRWCVQKDSWYLSLFWILSILCGTFQFQTLIRALLKDSSSNLAYSCVYFIFYAFQILVLILSAFSEKDDSSKNPSTTASFLSSITFSWYDSTVLKGFRKPLTLEDIWDIEDAAKTKALVSRFEKYMAEELQKARRAFQKRQKKKSKRNPGASVNGLDKNQSQSQDVLVLEETKKKKKKSETTKDFPKSWLVKALFKTFYVILLKSFLLKVVYDILTFLNPQLLKLLIAFANDRGIYLWTGYLYSILLFVVALIQSFCLQYYFQLCFMLGMKVRTTIMASVYKKALTVSNRARKQYTIGETVNLMSVDAQKLMDVTNFIHLLWSNVLQIALAIYFLWAELGPSVLAGVGVMVILIPINGVLATRNRAIQVKNMKNKDSRLKIMNEILSGIKILKYFAWEPSFQNQVHNLRKKELRNLLRFGQLQSAIMFLLYLTPVLVSVITFSVYVLVDSSNVLDAQKAFTSITLFNILRFPMSMLPMLISSMLQASVSTERLEKYLGGDDLDTSAIRHDCNSDKAVQFSEASFTWDHDLGVTIQDVNLDIMPGQLVAVVGTVGSGKSSLMSAMLGEMENVHGHITVKGSVAYVPQQSWIQNGTIKENILFGSELDEKKYQRVLEACALLPDLEVLPGGDMAEIGEKGINLSGGQKQRISLARATYQNSDIYILDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRILVTHSIHFLPQVDEIVVVGNGTIMEKGSYSTLLANKGLFAKNLKTFVKQTGPEDEATVNEDSEDDDCGLVPSVEEIPEDVASLSMKKENDLHRTLSRRSRSSSRHLKSLKDSLKIRNANILKEEEEPVRGQKLIKKEFVQTGKVKFSIYLKYLQAIGWCSIVFILLGFVIYYVAFIGSNLWLSAWTSDSKIYNGTNYPSSQRDLRVGVYGALGVAQGLFVFIANIWSVYGCNHASNILHKQLLNNILRAPMSFFDTTPIGRIVNRFAGDISTVDDTLPMSLRSWVLCFLGIISTLVMICLATPIFVVVIIPLGIIYVSVQIFYVATSRQLRRLDSVTRSPIYSHFSETVSGLSVIRAFEHQQRFLKQSETAIDTNQKCVFSWITSNRWLAVRLELIGNLIVFFASLMMVIYRNNLSGDTVGFVLSNALNITQTLNWLVRMTSEIETNIVAVERITEYINVENEAPWVTDKRPPEGWPSKGEIQFSNYQVRYRPELDLVLKGITCDIKSTEKIGVVGRTGAGKSSLTNCLFRILEAAGGQITIDGVDIASIGLHDLREKLTIIPQDPILFSGSLRMNLDPFNNYSDEEIWKALELSHLKSFVAGLQAGLSYEVTEGGDNLSIGQRQLLCLARALLRKSKILIMDEATAAVDLETDQLIQTTIQTEFSHCTTITIAHRLHTIMDSDKVMVLDSGKIVEYDSPEELLKNPGPFYFMAQEAGIENTNSTTF", "length": 1543 }, "evidence": [ { "id": "A0A9J7JH75", "url": "https://omabrowser.org/oma/group/A0A9J7JH75/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0ZMB9-1", "protein_name": "ATP binding cassette subfamily C member 2", "gene_name": "ABCC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAALEEFCGSVFWNDSFLARPDADLPVCFQQTVLVWIPLGFLWVLAPWQLLPICKSKSKKSSKTKLYIIKQVLATLLLMTAVAELVLAITEGTGQDPLPAVLYTNPSLYIVTWVLVLLIHYARSFCLCRDSVVLFCFWILSLLSGILPFQSLVRRALQDPIVDVPRFVLFFISYGLQLLLFLVSAFSDISPEAKEIAKKNPEMTASILSSVTFEWYSRMVYKGHRKPLEIEDVWELKDKDRTQAIHATFEKNMKTALRKAQAELEKRKRKKRRREHDTEHMNGMSKAQSQDVLVLEEKQPKKKKKKGGKEDSSHKDYPKKWLMKALFRTFLQNLMMSVAFKLVHDVLVFVSPQLLKLLITFVSDAEAFAWQGYLYSILLFLTAMLQSLCLQQYFNLCFQLGTNVRASLIAAIYKKALTMSSATRKESTVGETVNLMSADAQRFMDMANFVHQLWSSPLQIILSIVFLWGELGPSVLAGLAVMVLLIPINGFLVNKSKHIQVRNMKNKDERMKIMGEVLNGIKILKLFAWEPSFEKRINEIRACELKDLLKFSYLQSVSIFVFTCAPFLVSLASFAVYVLVDENNVLDAQKAFTSISLFNVLRFPMAMLPLVLSSMVQTNVSKERLERYLGGEDLDTSAIHHDSIPGSAVRFTEATFTWEQDGNAVIRDVTLDIKPGSLVAVVGAVGSGKSSLISAMLGEMENIKGHINIQGSLAYVPQQAWIQNATLKDNILFGSELDEARYQKVIKACALLPDLELLPAGDQTEIGEKGINLSGGQKQRVSLARAVYNDADIYILDDPLSAVDAHVGKHLFEHVLGPKGLLQKKTRILVTHSISFLPQVDNIVVLVAGAVSEHGSYSTLLANRGAFAQFLNSYGSQEEGAAEETTAAAGLDGIEEQGDESMEPCVEEGPDDVVTMTLKREASIHRKEFTRSISTQSTTSVKAQEEPNKIKGQRLIEKEAVETGKVKFSMYLRYLRAVGLGFSFCVAMSYVGEYAAYVGTNLWLSAWTDDAERYRNETYPVQQRDLRIGVFGALGVSQALFLFLATILSSHGAMRASRIVHEQLLSNILRVPMSFFDTTPTGRIVNRFAKDIFTVDETIPMSFRSWLNCFMGIISTLLMIALATPFFTVVIVPLGIFYYFVLRFYISTSRQLRRLDSVTRSPIYSHFGETVSGLSVIRAYGHQQRFLQQNERTMDINQKSVYSWIVSNRWLAIRLEFVGSLVVFFSALLAVISRNSLEGGIVGLSVSSALNVTQTLNWLVRVSSELETNIVAVERVHEYTKVKREAPWVTDKRPPHSWPSKGEIQFVDYKVRYRPELELVLQGITCSIGSTEKVGVVGRTGAGKSSLTNCLFRVLEAAGGKIIIDGLDIATIGLHDLRQNLTIIPQDPVLFTGTLRMNLDPFDQYTDEEVWKALELAHLKAYVQELPERLQHVVSEGGENLSVGQRQLVCLARALLRKAKILILDEATAAVDLETDHLIQTTIRSAFADCTVLTIAHRLHTIMDSNRVMVMHAGKIVEFDSPEKLLQKQSVFSAMAKDAGITNTETTTL", "length": 1550 }, "evidence": [ { "id": "A0A9J7JH75", "url": "https://omabrowser.org/oma/group/A0A9J7JH75/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S8V9-1", "protein_name": "Multidrug resistance-associated protein 1", "gene_name": "ABCC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLEKFCNSTFWNSSFLDSEVDLPLCFEQTVLVWIPLGFLWLLAPWQLIHVYRSRTKRSPITKLYLAKQVLVGFLFILAAIELVLAFTEDTGQATVPAVRYTNPILYLATWILVLLIQHSRRWCVQKDSWYLSLFWILSILCSTFQFQTLIRMLLKGDNSHLGYSCVFFICYALQILVLILAAFSEKSNSSKNPSSTASFLSSITFSWYDSVVLKGYKEPLTLEDVWDVAEESKTKRLVSRFEAHMAGELQKAKRAFQKRQQKKSQQKSGAKPQVLDKNQSQSQDVLVLEETKKKKKKKSETTEDFPKSWLVKVLLKTFPSILLKSFLLKLVYDISSFLNPQLLKLLISFASDRGVYVWTGYLYSILFFVVALLQSFCLQSYFKLCFLLGMQVRTSVMASVYKKALTLSNRARKQYTVGETVTLMSVDAQKLMDVTNFIHLLWSNVLQIVLSIYFLWAELGPSVLAGVGVMVLLIPLNGVLATKNRAIQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFQNQVHNLRKKELRNLLTFGQLQSVMMFLLNLTPVLVSVVTFSVYVLVDSNNILDAEKAFTSITLFNILRFPMSMLPMVISSMLQASVSVERLEKYLGGDDLDTSAIRRDGNSDKAVQFSEASFTWDRDLEATVRDVNLDIMPGQFVAVVGTVGSGKSSLMSAMLGEMENIHGHVTVKGTVAYVPQQSWIQNGIKDNILFGSEFNEKKYQKILEACALLPDLEVLPGGDLAEIGEKGINLSGGQKQRISLARATYQNSDIYILDDPLSAVDAHVGRHIFNKVLGPNGLLKGKTRLLVTHSIHFLPQVDEIVVVGNGTILEKGSYSALLAKKGVFAKNLKTFVKEAGPEDEATVNEDSEEDACELMPSVEENPEDAASLKRENSLRQTLSRSSRSSSRRLKSLKDSLKTRKGNILKEEETEPVKGQKLIKKEFLQTGKVKFSIYLKYLQAIGWCSIVFIVLGFMLYSVAFIGSNFWLSAWTGDSKIYNSTNYPTSQRDLRVGVFGALGLAQGIFVLIATLCSVYGCTHASSILHTQLLSNILRAPMSFFDTTPIGRIVNRFAGDISTLDDTLPMSLRSWLMCFLGIISTLVMICLATPVFVIIIIPLGIIYVAVQIFYVATSRQLRRLDSVTRSPIYSHFSETVSGLPVIRAFEHQQRFLKHNEITIDTNQKCVFSWIISNRWLAVRLEFIGNMIVFCSSLMMVIYRNTLSGDTVGFVLSNALNITQTLNWLVRMTSEIETNIVAVERINEYIHVENEAPWVTDKRPPDGWPSKGEIQFSNYQVRYRPELDLVLKGITCDIKSTEKIGVVGRTGAGKSSLTNSLFRILEAAGGQITIDGVDIASIGLHDLREKLTIIPQDPILFSGTLRMNLDPFNSYSDEELWKALELAHLKSFVSHLQLGLSYEVTEGGDNLSIGQRQLLCLARALLRKSKILIMDEATAAVDLETDHLIQMTIQTEFSHCTTITIAHRLHTIMDSDKVMVLDNGNIVQYDSPEELLKTPGPFYYMAQEAGIENTHSTAF", "length": 1541 }, "evidence": [ { "id": "A0A9J7JH75", "url": "https://omabrowser.org/oma/group/A0A9J7JH75/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q63120-1", "protein_name": "ATP-binding cassette sub-family C member 2", "gene_name": "Abcc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKFCNSTFWDLSLLESPEADLPLCFEQTVLVWIPLGFLWLLAPWQLYSVYRSRTKRSSITKFYLAKQVFVVFLLILAAIDLSLALTEDTGQATVPPVRYTNPILYLCTWLLVLAVQHSRQWCVRKNSWFLSLFWILSVLCGVFQFQTLIRALLKDSKSNMAYSYLFFVSYGFQIVLLILTAFSGPSDSTQTPSVTASFLSSITFSWYDRTVLKGYKHPLTLEDVWDIDEGFKTRSVTSKFEAAMTKDLQKARQAFQRRLQKSQRKPEATLHGLNKKQSQSQDVLVLEEAKKKSEKTTKDYPKSWLIKSLFKTFHVVILKSFILKLIHDLLVFLNPQLLKLLIGFVKSSNSYVWFGYICAILMFAVTLIQSFCLQSYFQHCFVLGMCVRTTVMSSIYKKALTLSNLARKQYTIGETVNLMSVDSQKLMDATNYMQLVWSSVIQITLSIFFLWRELGPSILAGVGVMVLLIPVNGVLATKIRNIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFQEQVQGIRKKELKNLLRFGQLQSLLIFILQITPILVSVVTFSVYVLVDSANVLNAEKAFTSITLFNILRFPLSMLPMVTSSILQASVSVDRLERYLGGDDLDTSAIRRVSNFDKAVKFSEASFTWDPDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLVSAMLGEMENVHGHITIQGSTAYVPQQSWIQNGTIKDNILFGSEYNEKKYQQVLKACALLPDLEILPGGDMAEIGEKGINLSGGQKQRVSLARAAYQDADIYILDDPLSAVDAHVGKHIFNKVVGPNGLLAGKTRIFVTHGIHFLPQVDEIVVLGKGTILEKGSYRDLLDKKGVFARNWKTFMKHSGPEGEATVNNDSEAEDDDDGLIPTMEEIPEDAASLAMRRENSLRRTLSRSSRSSSRRGKSLKNSLKIKNVNVLKEKEKEVEGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSILFIILFYGLNNVAFIGSNLWLSAWTSDSDNLNGTNNSSSHRDMRIGVFGALGLAQGICLLISTLWSIYACRNASKALHGQLLTNILRAPMRFFDTTPTGRIVNRFSGDISTVDDLLPQTLRSWMMCFFGIAGTLVMICMATPVFAIIIIPLSILYISVQVFYVATSRQLRRLDSVTKSPIYSHFSETVTGLPIIRAFEHQQRFLAWNEKQIDINQKCVFSWITSNRWLAIRLELVGNLVVFCSALLLVIYRKTLTGDVVGFVLSNALNITQTLNWLVRMTSEAETNIVAVERISEYINVENEAPWVTDKRPPADWPRHGEIQFNNYQVRYRPELDLVLKGITCNIKSGEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDVASIGLHDLRERLTIIPQDPILFSGSLRMNLDPFNKYSDEEVWRALELAHLRSFVSGLQLGLLSEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRKEFSQCTVITIAHRLHTIMDSDKIMVLDNGKIVEYGSPEELLSNRGSFYLMAKEAGIENVNHTEL", "length": 1541 }, "evidence": [ { "id": "A0A9J7JH75", "url": "https://omabrowser.org/oma/group/A0A9J7JH75/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VI47-1", "protein_name": "ATP-binding cassette sub-family C member 2", "gene_name": "Abcc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEFCNSTFWNLSLLKSPEADLPLCFEQTVLVWIPLGFLWLLAPWQLYRIYRSRTKRFAITKFYLAKQVFVVCLLILAAIDLSLALTEDTGQATIPPVKYTNPILYLCTWLLVLVIQHCRQCCIQKNSWFLSMFWILSLLCGIFQFQTLIRALLQDSKSNMTYSCLFFVSYGFQIVILILSAFSESSDSTHAPSATASFLSSVTFSWYDSTVLKGYKHPLTIEDVWDIEENLKAKSLTSKFKTIMTKDLQKARQALQRRLKKSQQSPEGTSHGLTKKQSQSQDVLVLEDSKKKKKKSEATKDFPKSWLVKALFKTFYVVILKSFILKLAHDILLFLNPQLLKFLIGFVKDPDSYPWVGYIYAILMFSVTLIQSFFLQCYFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVDSQKLMDVTNYIHLLWSSVLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRKKELRNLLRFSQLQTILIFILHLTPTLVSVITFSVYVLVDSQNVLNAEKAFTSITLFNILRFPLAMLPMVISSVIQASVSVDRLEQYLGSDDLDLSAIRHVCHFDKAVQFSEASFTWDRDLEATIQDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNILFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYILDDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLMDKKGVFAKNWKTFMKHSGPEGEATVDNDSEEEDGDCGLIPTVEEIPDDAASLTMRRENSLRRTLSRSSRSGSRRGKSLKSSLKIKSVNALNKKEEVVKGQKLIKKEFVETGKVKFSIYLKYLQAVGWWSLLFIVIFYVLNYVAFIGTNLWLSAWTSDSEKQNGTDNSPSQRDMRIGVFGALGIAQGIFLLSSSLWSIYACRNASKTLHRQLLTNILRAPMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLRSWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSETVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYKNSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEYINVDNEAPWVTDKKPPADWPKKGEIQFNNYQVRYRPELDLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGGQIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAGLQLGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQCTVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLSNMGPFYLMAKEAGIESVNHTEL", "length": 1543 }, "evidence": [ { "id": "A0A9J7JH75", "url": "https://omabrowser.org/oma/group/A0A9J7JH75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92887-1", "protein_name": "ATP-binding cassette sub-family C member 2", "gene_name": "ABCC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLEKFCNSTFWNSSFLDSPEADLPLCFEQTVLVWIPLGYLWLLAPWQLLHVYKSRTKRSSTTKLYLAKQVFVGFLLILAAIELALVLTEDSGQATVPAVRYTNPSLYLGTWLLVLLIQYSRQWCVQKNSWFLSLFWILSILCGTFQFQTLIRTLLQGDNSNLAYSCLFFISYGFQILILIFSAFSENNESSNNPSSIASFLSSITYSWYDSIILKGYKRPLTLEDVWEVDEEMKTKTLVSKFETHMKRELQKARRALQRRQEKSSQQNSGARLPGLNKNQSQSQDALVLEDVEKKKKKSGTKKDVPKSWLMKALFKTFYMVLLKSFLLKLVNDIFTFVSPQLLKLLISFASDRDTYLWIGYLCAILLFTAALIQSFCLQCYFQLCFKLGVKVRTAIMASVYKKALTLSNLARKEYTVGETVNLMSVDAQKLMDVTNFMHMLWSSVLQIVLSIFFLWRELGPSVLAGVGVMVLVIPINAILSTKSKTIQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFRDQVQNLRKKELKNLLAFSQLQCVVIFVFQLTPVLVSVVTFSVYVLVDSNNILDAQKAFTSITLFNILRFPLSMLPMMISSMLQASVSTERLEKYLGGDDLDTSAIRHDCNFDKAMQFSEASFTWEHDSEATVRDVNLDIMAGQLVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGTTAYVPQQSWIQNGTIKDNILFGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLDIYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYSALLAKKGEFAKNLKTFLRHTGPEEEATVHDGSEEEDDDYGLISSVEEIPEDAASITMRRENSFRRTLSRSSRSNGRHLKSLRNSLKTRNVNSLKEDEELVKGQKLIKKEFIETGKVKFSIYLEYLQAIGLFSIFFIILAFVMNSVAFIGSNLWLSAWTSDSKIFNSTDYPASQRDMRVGVYGALGLAQGIFVFIAHFWSAFGFVHASNILHKQLLNNILRAPMRFFDTTPTGRIVNRFAGDISTVDDTLPQSLRSWITCFLGIISTLVMICMATPVFTIIVIPLGIIYVSVQMFYVSTSRQLRRLDSVTRSPIYSHFSETVSGLPVIRAFEHQQRFLKHNEVRIDTNQKCVFSWITSNRWLAIRLELVGNLTVFFSALMMVIYRDTLSGDTVGFVLSNALNITQTLNWLVRMTSEIETNIVAVERITEYTKVENEAPWVTDKRPPPDWPSKGKIQFNNYQVRYRPELDLVLRGITCDIGSMEKIGVVGRTGAGKSSLTNCLFRILEAAGGQIIIDGVDIASIGLHDLREKLTIIPQDPILFSGSLRMNLDPFNNYSDEEIWKALELAHLKSFVASLQLGLSHEVTEAGGNLSIGQRQLLCLGRALLRKSKILVLDEATAAVDLETDNLIQTTIQNEFAHCTVITIAHRLHTIMDSDKVMVLDNGKIIECGSPEELLQIPGPFYFMAKEAGIENVNSTKF", "length": 1545 }, "evidence": [ { "id": "A0A9J7JH75", "url": "https://omabrowser.org/oma/group/A0A9J7JH75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9LK64-1", "protein_name": "ABC transporter C family member 3", "gene_name": "ABCC3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDFLGSTTGSGTLAMLFSFSESILPLDSRSFLLKPLFLRWLSGFLHSVLLLVLFFSWVRKKIRGDSGVTESLKDRRDFGFKSALFCSLALSLLNLVLMSLSGFYWYESGWLDNEQLVSSLGFLLGMVSWGVLSICLHRCRDCEHKKAPFLLRLWLVFYLVVSCYSLVVDFVMYERRETVPVHLLVFDIVAFIAAVFLGYVAVLKKDRSNSNGVLEEPLLNGGDSRVGGDDSVELNKTNGSGEATPYSRAGILSLLTFSWMSPLIDIGNKKTLDLEDVPQLHDTDSVVGLAPKFRSMLESPDGGERSGVTTFKLIKALYFTAQWEILVTAFFAFIYTVASYVGPALIDTFVQYLNGRRQYNHEGYVLVITFFAAKIVECLSQRHWFFRLQKVGIRMRSALVAMIYEKGLTLSCQSKQGRTSGEIINFMTVDAERIGNFSWYMHDPWMVLLQVGLALWILYRNLGLASIAALVATIIVMLINFPFGRMQERFQEKLMEAKDSRMKSTSEILRNMRILKLQGWEMKFLSKIFDLRKSEEGWLKKYVYNSAVISFVFWGAPTLVSVSTFGACILLGIPLESGKILSALATFRILQEPIYNLPDTISMIVQTKVSLDRLASYLCLDNLQPDIVERLPKGSSDVAVEVINSTLSWDVSSSNPTLKDINFKVFPGMKVAVCGTVGSGKSSLLSSLLGEVPKVSGSLKVCGTKAYVAQSPWIQSGKIEDNILFGKPMERERYDKVLEACSLSKDLEILSFGDQTVIGERGINLSGGQKQRIQIARALYQDADIYLFDDPFSAVDAHTGSHLFKEVLLGLLCSKSVIYVTHQVEFLPAADLILVMKDGRISQAGKYNDILNSGTDFMELIGAHQEALAVVDSVDANSVSEKSALGQENVIVKDAIAVDEKLESQDLKNDKLESVEPQRQIIQEEEREKGSVALDVYWKYITLAYGGALVPFILLGQVLFQLLQIGSNYWMAWATPVSEDVQAPVKLSTLMIVYVALAFGSSLCILLRATLLVTAGYKTATELFHKMHHCIFRSPMSFFDSTPSGRIMSRASTDQSAVDLELPYQFGSVAITVIQLIGIIGVMSQVSWLVFLVFIPVVAASIWYQRYYIAAARELSRLVGVCKAPLIQHFSETISGATTIRSFSQEFRFRSDNMRLSDGYSRPKFYTAGAMEWLCFRLDMLSSLTFVFSLVFLVSIPTGVIDPSLAGLAVTYGLSLNTLQAWLIWTLCNLENKIISVERILQYASVPSEPPLVIESNRPEQSWPSRGEVEIRDLQVRYAPHMPLVLRGITCTFKGGLRTGIVGRTGSGKSTLIQTLFRIVEPSAGEIRIDGVNILTIGLHDLRLRLSIIPQDPTMFEGTMRSNLDPLEEYTDDQIWEALDKCQLGDEVRKKEQKLDSSVSENGDNWSMGQRQLVCLGRVLLKRSKILVLDEATASVDTATDNLIQKTLREHFSDCTVITIAHRISSVIDSDMVLLLSNGIIEEYDTPVRLLEDKSSSFSKLVAEYTSRSSSSFD", "length": 1514 }, "evidence": [ { "id": "A0A9J7JH75", "url": "https://omabrowser.org/oma/group/A0A9J7JH75/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75" } ], "pmid": "" }, { "name": "ABC-type xenobiotic transporter activity", "id": "GO:0008559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008559", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JH75" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JH75", "url": 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027258077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258077" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dmrtb1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD0", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100772202", "url": "https://www.ncbi.nlm.nih.gov/gene/100772202", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036407", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036407", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772202", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772202", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JHD0", "url": "https://www.orthodb.org/?gene=A0A9J7JHD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12322:SF66", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12322:SF66", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00751", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00751", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027258077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258077", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JHD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRTPKCSRCRNHGYLVPVKGHAGKCRWKHCICDKCYLITERQKIMAAQKVLKTQAAEEQGSQLPPGAPVVAAASSSSSICALPRVAPGGVGPGPVVAAACFLERPPQARSPGPNAFQLVPGGRPGPGTLQPGPGGPGGAPDRPSAWLPQLSPQVARPEPCGPEQLLPVRPVPRLPFADYGHPLRFSSDHVAGAGYPEREPFKQCPACVPMPSYQPFPLDGQDASSAVGIPQQRSFRHVSCSPYHGGSLVPEPARDLQPTYCSPPPPPLPPPPSQPQQSQFLPPGYLSALHYLPPPPPPPSPPSFSLTIMYDTEKETNNGQDAEAPREPSQHASQEHSSQEQSN", "length": 344, "header": "tr|A0A9J7JHD0-1|A0A9J7JHD0_CRIGR Isoform 1 of LOW QUALITY PROTEIN: doublesex- and mab-3-related transcription factor B1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dmrtb1 PE=3 SV=1 CANONICAL=A0A9J7JHD0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JHD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHD0/entry#A0A9J7JHD0-1", "sequence": { "sequence": "MLRTPKCSRCRNHGYLVPVKGHAGKCRWKHCICDKCYLITERQKIMAAQKVLKTQAAEEQGSQLPPGAPVVAAASSSSSICALPRVAPGGVGPGPVVAAACFLERPPQARSPGPNAFQLVPGGRPGPGTLQPGPGGPGGAPDRPSAWLPQLSPQVARPEPCGPEQLLPVRPVPRLPFADYGHPLRFSSDHVAGAGYPEREPFKQCPACVPMPSYQPFPLDGQDASSAVGIPQQRSFRHVSCSPYHGGSLVPEPARDLQPTYCSPPPPPLPPPPSQPQQSQFLPPGYLSALHYLPPPPPPPSPPSFSLTIMYDTEKETNNGQDAEAPREPSQHASQEHSSQEQSN", "length": 344, "header": "tr|A0A9J7JHD0-1|A0A9J7JHD0_CRIGR Isoform 1 of LOW QUALITY PROTEIN: doublesex- and mab-3-related transcription factor B1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dmrtb1 PE=3 SV=1 CANONICAL=A0A9J7JHD0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263499" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHG3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pak1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHG3", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01093", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01093", "database": "CDD", "categories": [ "Protein Classification" ] }, 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CANONICAL=A0A9J7JHG3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHG3/entry#A0A9J7JHG3-1", "sequence": { "sequence": "MSWMSGASGERYCLLWSTWKYVKLLLVVVTMSNNGLDIQDKPPAPPMRNTSTMIGAGSKDTGTLNHGSKPLPPNPEEKKKKDRFYRSILPGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKTVSETPAVPPVSEDEDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTAPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKNSH", "length": 574, "header": "tr|A0A9J7JHG3-1|A0A9J7JHG3_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=Pak1 PE=3 SV=1 CANONICAL=A0A9J7JHG3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 241, "start_aa": "Thr", "end_pos": 241, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr241", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHG3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHG3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767503", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767503", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHG3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHG3" } ], "pmid": "" }, { "name": "collagen binding", "id": "GO:0005518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005518", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHG3" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHG3" } ], "pmid": "" }, { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHG3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { 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}, { "uniprot_ac": "A0A8C2MPK3", "gene_name": "Mcm6", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPK3" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8C2MPK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MPK3" } ] } ] }, { "uniprot_ac": "A0A8C2MQ86", "gene_name": "Ddx50", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MQ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ86" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MQ86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ86" } ] } ] }, { "uniprot_ac": "A0A8C2MVH8", "gene_name": "Mcm7", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVH8" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A8C2MVH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MVH8" } ] } ] }, { "uniprot_ac": "A0A8C2MWE0", "gene_name": "Snrnp200", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWE0" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A8C2MWE0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWE0" } ] } ] }, { "uniprot_ac": "A0A8C2MWH4", "gene_name": "Ddx25", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2MWH4", "database": "UniProtKB", "url": 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"A0A8C2N055", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N055" } ] } ] }, { "uniprot_ac": "A0A8C2N184", "gene_name": "Entpd8", "activity": [ { "ec_number": "3.6.1.5", "activity": "a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O = a 2'-deoxyribonucleoside 5'-phosphate + 2 phosphate + 2 H(+).", "evidence": [ { "id": "A0A8C2N184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N184" } ] }, { "ec_number": "3.6.1.5", "activity": "", "evidence": [ { "id": "A0A8C2N184", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N184" } ] } ] }, { "uniprot_ac": "A0A8C2N236", "gene_name": "Atp13a4", "activity": [ { "ec_number": "7.2.2.-", "activity": "", "evidence": [ { "id": "A0A8C2N236", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N236" } ] } ] }, { "uniprot_ac": "A0A8C2N386", "gene_name": "Vcp", "activity": [ { "ec_number": "3.6.4.6", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] }, { "ec_number": "3.6.4.6", "activity": "", "evidence": [ { "id": "A0A8C2N386", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N386" } ] } ] }, { "uniprot_ac": "A0A8C2QH91", "gene_name": "Ino80", "activity": [ { "ec_number": "3.6.4.-", "activity": "", "evidence": [ { "id": "A0A8C2QH91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH91" } ] } ] }, { "uniprot_ac": "A0A8C2QHV1", "gene_name": "Ddx20", "activity": [ { "ec_number": "3.6.1.15", "activity": "a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHV1" } ] }, { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A8C2QHV1", "database": "UniProtKB", "url": 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translocating in the 5'-3' direction.", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] }, { "ec_number": "5.6.2.3", "activity": "", "evidence": [ { "id": "A0A9J7F9W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9W3" } ] } ] }, { "uniprot_ac": "A0A9J7FCH5", "gene_name": "Mov10l1", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCH5" } ] } ] }, { "uniprot_ac": "A0A9J7FI19", "gene_name": "Xrcc6", "activity": [ { "ec_number": "4.2.99.18", "activity": "2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "4.2.99.18", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7FI19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI19" } ] } ] }, { "uniprot_ac": "A0A9J7FI42", "gene_name": "Fbh1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FI42", "database": "UniProtKB", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FPK3" } ] } ] }, { "uniprot_ac": "A0A9J7FTT2", "gene_name": "Mcm5", "activity": [ { "ec_number": "3.6.4.12", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] }, { "ec_number": "3.6.4.12", "activity": "", "evidence": [ { "id": "A0A9J7FTT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTT2" } ] } ] }, { "uniprot_ac": "A0A9J7FU33", "gene_name": "Eif4a2", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FU33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU33" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FU33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FU33" } ] } ] }, { "uniprot_ac": "A0A9J7FUH6", 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"activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7FYM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYM8" } ] } ] }, { "uniprot_ac": "A0A9J7G1N4", "gene_name": "Fancm", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7G1N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1N4" } ] } ] }, { "uniprot_ac": "A0A9J7G2T1", "gene_name": "Dhx9", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7G2T1", "database": "UniProtKB", "url": 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phosphate + H(+).", "evidence": [ { "id": "A0A9J7GCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ] }, { "ec_number": "3.6.4.13", "activity": "", "evidence": [ { "id": "A0A9J7GCV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GCV1" } ] } ] }, { "uniprot_ac": "A0A9J7GDX9", "gene_name": "Hfm1", "activity": [ { "ec_number": "5.6.2.4", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ] }, { "ec_number": "5.6.2.4", "activity": "", "evidence": [ { "id": "A0A9J7GDX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDX9" } ] } ] }, { "uniprot_ac": "A0A9J7GF88", "gene_name": "Dhx33", "activity": [ { "ec_number": "3.6.4.13", "activity": "ATP + H2O = ADP + phosphate + H(+).", "evidence": [ { "id": "A0A9J7GF88", "database": "UniProtKB", "url": 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Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260825" } ] }, { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHP4#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHP4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773191", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHP4", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100773191", "url": "https://www.ncbi.nlm.nih.gov/gene/100773191", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773191", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773191", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JHP4", "url": "https://www.orthodb.org/?gene=A0A9J7JHP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260825", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260825", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JHP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSMVKCSNIDHFSLSVQISKYRGTEFHPSVFLLLGVPGLEVMHVWIGFPFGFVYLIALFGKISILFVIKSEHSLHQLMYYFLAMLGSIDLGLSTFIILKMLGIFWFNLQEISFEGCVTQMFFIHIFTAIETVVLVAIAFDRYVAICNPLQYSLILMNKVIGLILVVVFGANFMLVIPLVFLILRLPFCGHHIIPHTYCEHMGIARLACANIKVNMIFGLILISLVLADVLLIAISYIHILRAVFNLPSWDARLKALNKYGPHICVILVFFTPAFFSFMTHRFGKNVPAYIHILLSNLYVVVSPALNPVIYGVETKLIQEQVLNIFWKKS", "length": 329, "header": "tr|A0A9J7JHP4-1|A0A9J7JHP4_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100773191 PE=3 SV=1 CANONICAL=A0A9J7JHP4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JHP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHP4/entry#A0A9J7JHP4-1", "sequence": { "sequence": "MSMVKCSNIDHFSLSVQISKYRGTEFHPSVFLLLGVPGLEVMHVWIGFPFGFVYLIALFGKISILFVIKSEHSLHQLMYYFLAMLGSIDLGLSTFIILKMLGIFWFNLQEISFEGCVTQMFFIHIFTAIETVVLVAIAFDRYVAICNPLQYSLILMNKVIGLILVVVFGANFMLVIPLVFLILRLPFCGHHIIPHTYCEHMGIARLACANIKVNMIFGLILISLVLADVLLIAISYIHILRAVFNLPSWDARLKALNKYGPHICVILVFFTPAFFSFMTHRFGKNVPAYIHILLSNLYVVVSPALNPVIYGVETKLIQEQVLNIFWKKS", "length": 329, "header": "tr|A0A9J7JHP4-1|A0A9J7JHP4_CRIGR Isoform 1 of Olfactory receptor OS=Cricetulus griseus OX=10029 GN=LOC100773191 PE=3 SV=1 CANONICAL=A0A9J7JHP4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JHQ7-1", "uniprot_ac": "A0A9J7JHQ7", "uniprot_id": "A0A9J7JHQ7_CRIGR", "mass": { "chemical_mass": 100479.0, "monoisotopic_mass": 100479.0 }, "refseq": { "ac": "XP_007648955", "name": "LOW QUALITY PROTEIN: major vault protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648955" }, "gene_names": [ { "name": "Mvp", "type": "recommended", "evidence": [ { "id": "A0A9J7JHQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7" } ] }, { "name": "Mvp", "type": "synonym", "evidence": [ { "id": "XP_007648955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648955" } ] } ], "protein_names": [ { "name": "Major vault protein", "type": "recommended", "evidence": [ { "id": "A0A9J7JHQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: major vault protein", "type": "synonym", "evidence": [ { "id": "XP_007648955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648955" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614830.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007648955.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007648955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648955" } ] }, { "annotation": "Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7#function" }, { "database": "UniProtKB", "id": "ARBA00025300", "url": "https://www.uniprot.org/uniprotkb/ARBA00025300#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mvp", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHQ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHQ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08825", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08825", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751094", "url": "https://www.ncbi.nlm.nih.gov/gene/100751094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751094", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751094", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JHQ7", "url": "https://www.orthodb.org/?gene=A0A9J7JHQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14165:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14165:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17795", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17795", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007648955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648955", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JHQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEEAIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPVRMVTVPPRHYCIVANPVSRDAQSLVLFDTTGQVRLRHADQEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTALHLKALLDFKDENGDTIMAGDEWLFEGPGTYIPQKEVEVVEIIQATVIRQNQALRLRARKECFDRDGKQRVTGEEWLVRSVGAYLPAVFEEVLDLVDAVILTEKTALHLRARQNFKDLRGVAHRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPRHYCVILDPMGPDGKNQLGQKRVVKGEKSFFLQPGERLERGIQDVYVLSEQQGLLLRALQPLEEGEGQEKVSHQAGDRWLIRGPLEYVPSAKVEVVEERQAIPLDQNEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPPGVEELLNLGHDPLADRGQKATAKTLQPSAPRNKTRVVSYRVPHNAAVQVYDYRAKRARVVFGPELVSLDPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFELKNRNDPEETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRMAVFGFETSADTGPDGTLLPRARDRATFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEAMSMAVESTGNAKAEAESRAEAARIEGEGSVLQAKLKAEALAIETEAELERVKKVRELELVYARAQLQLEVSKAQQLADVEAKKFKEMTEALGPGTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSSPINLFNTALGCWGWGLMVSHRHKSKVAGPARGRLAFASPPSSSLFEAATLCLRSTLTALMMDKIK", "length": 902, "header": "tr|A0A9J7JHQ7-1|A0A9J7JHQ7_CRIGR Isoform 1 of Major vault protein OS=Cricetulus griseus OX=10029 GN=Mvp PE=4 SV=1 CANONICAL=A0A9J7JHQ7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JHQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7/entry#A0A9J7JHQ7-1", "sequence": { "sequence": "MATEEAIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPVRMVTVPPRHYCIVANPVSRDAQSLVLFDTTGQVRLRHADQEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTALHLKALLDFKDENGDTIMAGDEWLFEGPGTYIPQKEVEVVEIIQATVIRQNQALRLRARKECFDRDGKQRVTGEEWLVRSVGAYLPAVFEEVLDLVDAVILTEKTALHLRARQNFKDLRGVAHRTGEEWLVTVQDTEAHVPDVHEEVLGVVPITTLGPRHYCVILDPMGPDGKNQLGQKRVVKGEKSFFLQPGERLERGIQDVYVLSEQQGLLLRALQPLEEGEGQEKVSHQAGDRWLIRGPLEYVPSAKVEVVEERQAIPLDQNEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPPGVEELLNLGHDPLADRGQKATAKTLQPSAPRNKTRVVSYRVPHNAAVQVYDYRAKRARVVFGPELVSLDPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFELKNRNDPEETAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRMAVFGFETSADTGPDGTLLPRARDRATFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEAMSMAVESTGNAKAEAESRAEAARIEGEGSVLQAKLKAEALAIETEAELERVKKVRELELVYARAQLQLEVSKAQQLADVEAKKFKEMTEALGPGTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSSPINLFNTALGCWGWGLMVSHRHKSKVAGPARGRLAFASPPSSSLFEAATLCLRSTLTALMMDKIK", "length": 902, "header": "tr|A0A9J7JHQ7-1|A0A9J7JHQ7_CRIGR Isoform 1 of Major vault protein OS=Cricetulus griseus OX=10029 GN=Mvp PE=4 SV=1 CANONICAL=A0A9J7JHQ7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751094", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751094", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JHQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7" }, { "id": "PF17794", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17794" }, { "id": "PF01505", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01505" }, { "id": "PF17796", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17796" }, { "id": "PF17795", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17795" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major vault protein repeat", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 109, "start_aa": "Met", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JHQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHQ7" }, { "id": "PF11978", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11978" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major vault protein shoulder", "eco_id": "ECO_0000259", "start_pos": 519, "end_pos": 647, "start_aa": "Gly", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JHU3-1", "uniprot_ac": "A0A9J7JHU3", "uniprot_id": "A0A9J7JHU3_CRIGR", "mass": { "chemical_mass": 100840.0, "monoisotopic_mass": 100840.0 }, "refseq": { "ac": "XP_016834833", "name": "protein FAM171A1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834833" }, "gene_names": [ { "name": "Fam171a1", "type": "recommended", "evidence": [ { "id": "A0A9J7JHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3" } ] }, { "name": "Fam171a1", "type": "synonym", "evidence": [ { "id": "XP_016834833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834833" } ] } ], "protein_names": [ { "name": "Protein FAM171A1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7JHU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3/entry#names_and_taxonomy" } ] }, { "name": "protein FAM171A1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016834833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834833" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613621.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016834833.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016834833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834833" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam171a1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHU3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHU3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756305", "url": "https://www.ncbi.nlm.nih.gov/gene/100756305", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048530", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048530", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049175", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049175", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756305", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756305", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JHU3", "url": "https://www.orthodb.org/?gene=A0A9J7JHU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31626", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31626", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31626:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31626:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016834833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016834833", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MFW8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MFW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5S9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K784", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K784", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K784-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K784-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCHQCPAQLCASYKTTLRASIEEESSPRMSCANAFYRDVHFEAQHHVPKEGSTLEVTLKVHISDASTHQPIADALIEIFANHVSVASGTSGADGVAFIKFQYKLGNQLIVTATKHAYVPNSAPWKPIRLPVFSSLSLGLLPERSATLMVYEDVVQIVSGFQGARPQPRVHFQRRALRLPENTSYSDLTAFLTAASSPTEVDSFPYLRGLDGNGTGNSTRYDLTPITAVSVHLLSSNGTPVMVDGPIYVTVPLATQSSLRHNAYVAAWRFDQKLGTWLKSGLGLVHQEGSQLTWTYIAPQLGYWVAAMSPPIPGPVVTQDITTYHTVFLLAILGGMAFILLVLLCLLLYYCRRKCLKPRQHHRKLQLPPALESSKRDQSTSMSHINLLFSRRASDYPGPLSVSSHSRPEAPGTKELMGGVHLEMMSPSGEGDLHTPMLKLSYSTSQEFSSREELLSHKEEDKSQTSFDNLTPSGTLGKDYHKSVEIFPLKARKSMEREGYEPPGKDDYRGSYNAMLSQPLFEKRDQEGLPSAGSKLTIQEHMYPAPSSPEKEQLLDRRPTECMMSRSVDHLERPTSFPRPGQLICCSSVDQVNDSVYRKVLPALVIPAHYMKLPGDHSYVSQPLVVPADQQLEIGRLQAELSNPHVGIFPHPSSQMQGQPLSSQAISQQHLQDAGTREWGSQNASMSESLSIPASLNDAALAQMNSEVQLLTEKALMELGGGKPLPHPRAWFVSLDGRSNAHVRHSYIDLQRAGRNGSNDASLDSGVDMNEPKSARKGRGDPLSLQQSHPPVQEHQQKEPRAHDSTAYTQLVYLDDMDQSSSECGTTVCTPEDSALRCLLEGSGRRSGGQLPSLQEETTKRTSDVPLEPLASPNQRRSANDEDEDDDDDDDQGEDKKSPWQKREERPLMAFNIK", "length": 913, "header": "tr|A0A9J7JHU3-1|A0A9J7JHU3_CRIGR Isoform 1 of Protein FAM171A1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Fam171a1 PE=3 SV=1 CANONICAL=A0A9J7JHU3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MFW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3/entry#A0A8C2MFW8-1", "sequence": { "sequence": "MSRSTALLLCLLGCHVWKAVTKTLREPGAGAQEVTLKVHISDASTHQPIADALIEIFANHVSVASGTSGADGVAFIKFQYKLGNQLIVTATKHAYVPNSAPWKPIRLPVFSSLSLGLLPERSATLMVYEDVVQIVSGFQGARPQPRVHFQRRALRLPENTSYSDLTAFLTAASSPTEVDSFPYLRGLDGNGTGNSTRYDLTPITAVSVHLLSSNGTPVMVDGPIYVTVPLATQSSLRHNAYVAAWRFDQKLGTWLKSGLGLVHQEGSQLTWTYIAPQLGYWVAAMSPPIPGPVVTQDITTYHTVFLLAILGGMAFILLVLLCLLLYYCRRKCLKPRQHHRKLQLPPALESSKRDQSTSMSHINLLFSRRASDYPGPLSVSSHSRPEAPGTKELMGGVHLEMMSPSGEGDLHTPMLKLSYSTSQEFSSREELLSHKEEDKSQTSFDNLTPSGTLGKDYHKSVEIFPLKARKSMEREGYEPPGKDDYRGSYNAMLSQPLFEKRDQEGLPSAGSKLTIQEHMYPAPSSPEKEQLLDRRPTECMMSRSVDHLERPTSFPRPGQLICCSSVDQVNDSVYRKVLPALVIPAHYMKLPGDHSYVSQPLVVPADQQLEIGRLQAELSNPHVGIFPHPSSQMQGQPLSSQAISQQHLQDAGTREWGSQNASMSESLSIPASLNDAALAQMNSEVQLLTEKALMELGGGKPLPHPRAWFVSLDGRSNAHVRHSYIDLQRAGRNGSNDASLDSGVDMNEPKSARKGRGDPLSLQQSHPPVQEHQQKEPRAHDSTAYTQLVYLDDMDQSSSECGTTVCTPEDSALRCLLEGSGRRSGGQLPSLQEETTKRTSDVPLEPLASPNQRRSANDEDEDDDDDDDQGEDKKSPWQKREERPLMAFNIK", "length": 891, "header": "tr|A0A8C2MFW8-1|A0A8C2MFW8_CRIGR Computationally mapped isoform of Protein FAM171A1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Fam171a1 PE=3 SV=1 CANONICAL=A0A9J7JHU3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3/entry#A0A9J7JHU3-1", "sequence": { "sequence": "MCHQCPAQLCASYKTTLRASIEEESSPRMSCANAFYRDVHFEAQHHVPKEGSTLEVTLKVHISDASTHQPIADALIEIFANHVSVASGTSGADGVAFIKFQYKLGNQLIVTATKHAYVPNSAPWKPIRLPVFSSLSLGLLPERSATLMVYEDVVQIVSGFQGARPQPRVHFQRRALRLPENTSYSDLTAFLTAASSPTEVDSFPYLRGLDGNGTGNSTRYDLTPITAVSVHLLSSNGTPVMVDGPIYVTVPLATQSSLRHNAYVAAWRFDQKLGTWLKSGLGLVHQEGSQLTWTYIAPQLGYWVAAMSPPIPGPVVTQDITTYHTVFLLAILGGMAFILLVLLCLLLYYCRRKCLKPRQHHRKLQLPPALESSKRDQSTSMSHINLLFSRRASDYPGPLSVSSHSRPEAPGTKELMGGVHLEMMSPSGEGDLHTPMLKLSYSTSQEFSSREELLSHKEEDKSQTSFDNLTPSGTLGKDYHKSVEIFPLKARKSMEREGYEPPGKDDYRGSYNAMLSQPLFEKRDQEGLPSAGSKLTIQEHMYPAPSSPEKEQLLDRRPTECMMSRSVDHLERPTSFPRPGQLICCSSVDQVNDSVYRKVLPALVIPAHYMKLPGDHSYVSQPLVVPADQQLEIGRLQAELSNPHVGIFPHPSSQMQGQPLSSQAISQQHLQDAGTREWGSQNASMSESLSIPASLNDAALAQMNSEVQLLTEKALMELGGGKPLPHPRAWFVSLDGRSNAHVRHSYIDLQRAGRNGSNDASLDSGVDMNEPKSARKGRGDPLSLQQSHPPVQEHQQKEPRAHDSTAYTQLVYLDDMDQSSSECGTTVCTPEDSALRCLLEGSGRRSGGQLPSLQEETTKRTSDVPLEPLASPNQRRSANDEDEDDDDDDDQGEDKKSPWQKREERPLMAFNIK", "length": 913, "header": "tr|A0A9J7JHU3-1|A0A9J7JHU3_CRIGR Isoform 1 of Protein FAM171A1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Fam171a1 PE=3 SV=1 CANONICAL=A0A9J7JHU3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3/entry#A0A9J7K5S9-1", "sequence": { "sequence": "MCHQCPAQLCASYKTTLRASIEEESSPRMSCANAFYRDVHFEAQHHVPKEGSTLEVTLKVHISDASTHQPIADALIEIFANHVSVASGTSGADGVAFIKFQYKLGNQLIVTATKHAYVPNSAPWKPIRLPVFSSLSLGLLPERSATLMVYEDVVQIVSGFQGTWLKSGLGLVHQEGSQLTWTYIAPQLGYWVAAMSPPIPGPVVTQDITTYHTVFLLAILGGMAFILLVLLCLLLYYCRRKCLKPRQHHRKLQLPPALESSKRDQSTSMSHINLLFSRRASDYPGPLSVSSHSRPEAPGTKELMGGVHLEMMSPSGEGDLHTPMLKLSYSTSQEFSSREELLSHKEEDKSQTSFDNLTPSGTLGKDYHKSVEIFPLKARKSMEREGYEPPGKDDYRGSYNAMLSQPLFEKRDQEGLPSAGSKLTIQEHMYPAPSSPEKEQLLDRRPTECMMSRSVDHLERPTSFPRPGQLICCSSVDQVNDSVYRKVLPALVIPAHYMKLPGDHSYVSQPLVVPADQQLEIGRLQAELSNPHVGIFPHPSSQMQGQPLSSQAISQQHLQDAGTREWGSQNASMSESLSIPASLNDAALAQMNSEVQLLTEKALMELGGGKPLPHPRAWFVSLDGRSNAHVRHSYIDLQRAGRNGSNDASLDSGVDMNEPKSARKGRGDPLSLQQSHPPVQEHQQKEPRAHDSTAYTQLVYLDDMDQSSSECGTTVCTPEDSALRCLLEGSGRRSGGQLPSLQEETTKRTSDVPLEPLASPNQRRSANDEDEDDDDDDDQGEDKKSPWQKREERPLMAFNIK", "length": 801, "header": "tr|A0A9J7K5S9-1|A0A9J7K5S9_CRIGR Computationally mapped isoform of Protein FAM171A1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Fam171a1 PE=3 SV=1 CANONICAL=A0A9J7JHU3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K784-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3/entry#A0A9J7K784-1", "sequence": { "sequence": "MCHQCPAQLCASYKTTLRASIEEESSPRMSCANAFYRDVHFEAQHHVPKEGSTLEVTLKVHISDASTHQPIADALIEIFANHVSVASGTSGADGVAFIKFQYKLGNQLIVTATKHAYVPNSAPWKPIRLPVFSSLSLGLLPERSATLMVYEDVVQIVSGFQGARPQPRVHFQRRALRLPENTSYSDLTAFLTAASSPTEVDSFPYLRGLDGNGTGTWLKSGLGLVHQEGSQLTWTYIAPQLGYWVAAMSPPIPGPVVTQDITTYHTVFLLAILGGMAFILLVLLCLLLYYCRRKCLKPRQHHRKLQLPPALESSKRDQSTSMSHINLLFSRRASDYPGPLSVSSHSRPEAPGTKELMGGVHLEMMSPSGEGDLHTPMLKLSYSTSQEFSSREELLSHKEEDKSQTSFDNLTPSGTLGKDYHKSVEIFPLKARKSMEREGYEPPGKDDYRGSYNAMLSQPLFEKRDQEGLPSAGSKLTIQEHMYPAPSSPEKEQLLDRRPTECMMSRSVDHLERPTSFPRPGQLICCSSVDQVNDSVYRKVLPALVIPAHYMKLPGDHSYVSQPLVVPADQQLEIGRLQAELSNPHVGIFPHPSSQMQGQPLSSQAISQQHLQDAGTREWGSQNASMSESLSIPASLNDAALAQMNSEVQLLTEKALMELGGGKPLPHPRAWFVSLDGRSNAHVRHSYIDLQRAGRNGSNDASLDSGVDMNEPKSARKGRGDPLSLQQSHPPVQEHQQKEPRAHDSTAYTQLVYLDDMDQSSSECGTTVCTPEDSALRCLLEGSGRRSGGQLPSLQEETTKRTSDVPLEPLASPNQRRSANDEDEDDDDDDDQGEDKKSPWQKREERPLMAFNIK", "length": 854, "header": "tr|A0A9J7K784-1|A0A9J7K784_CRIGR Computationally mapped isoform of Protein FAM171A1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam171a1 PE=3 SV=1 CANONICAL=A0A9J7JHU3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756305", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756305", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of cell shape", "id": "GO:0008360", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008360", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3" } ], "pmid": "" }, { "name": "stress fiber assembly", "id": "GO:0043149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043149", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHU3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 592, "end_pos": 594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 682, "end_pos": 684, "annotation": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JHW4-1", "uniprot_ac": "A0A9J7JHW4", "uniprot_id": "A0A9J7JHW4_CRIGR", "mass": { "chemical_mass": 50068.0, "monoisotopic_mass": 50068.0 }, "refseq": { "ac": "XP_003508788", "name": "elongation factor 1-gamma", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508788" }, "gene_names": [ { "name": "Eef1g", "type": "recommended", "evidence": [ { "id": "A0A9J7JHW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4" } ] }, { "name": "Eef1g", "type": "synonym", "evidence": [ { "id": "XP_003508788", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508788" } ] } ], "protein_names": [ { "name": "Elongation factor 1-gamma", "type": "recommended", "evidence": [ { "id": "A0A9J7JHW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4/entry#names_and_taxonomy" } ] }, { "name": "eEF-1B gamma", "type": "synonym", "evidence": [ { "id": "A0A9J7JHW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4/entry#names_and_taxonomy" } ] }, { "name": "elongation factor 1-gamma", "type": "synonym", "evidence": [ { "id": "XP_003508788", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508788" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614577.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508788", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508788" } ] }, { "annotation": "Probably plays a role in anchoring the complex to other cellular components.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4#function" }, { "database": "UniProtKB", "id": "ARBA00003468", "url": "https://www.uniprot.org/uniprotkb/ARBA00003468#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Eef1g", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4", "locus": {} } ], "crossref": [ { "id": "A0A9J7JHW4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JHW4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03181", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03181", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753545", "url": "https://www.ncbi.nlm.nih.gov/gene/100753545", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004046", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036282", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050802", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050802", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753545", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753545", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TQYFSWT", "url": "https://omabrowser.org/oma/group/TQYFSWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JHW4", "url": "https://www.orthodb.org/?gene=A0A9J7JHW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43986", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43986", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43986:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43986:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00043", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00043", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508788", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508788", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JHW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAHYVSNEDLRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAESQPKKETPRKEKGSREEKQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTVSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEGAFQHVGKNFNQGKIFK", "length": 437, "header": "tr|A0A9J7JHW4-1|A0A9J7JHW4_CRIGR Isoform 1 of Elongation factor 1-gamma OS=Cricetulus griseus OX=10029 GN=Eef1g PE=4 SV=1 CANONICAL=A0A9J7JHW4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JHW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4/entry#A0A9J7JHW4-1", "sequence": { "sequence": "MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAHYVSNEDLRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAESQPKKETPRKEKGSREEKQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTVSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEGAFQHVGKNFNQGKIFK", "length": 437, "header": "tr|A0A9J7JHW4-1|A0A9J7JHW4_CRIGR Isoform 1 of Elongation factor 1-gamma OS=Cricetulus griseus OX=10029 GN=Eef1g PE=4 SV=1 CANONICAL=A0A9J7JHW4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHW4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHW4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753545", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753545", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0G141-1", "protein_name": "Glutathione S-transferase domain-containing protein", "gene_name": "efa1G", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVMKLYTYPQNSRAFKSLIAAKYVNVDIEVPAFNFETDRLTEEFKTNFPLGKVPALLTEQGPLFESNTMARYVARLNNSTIYGSDAYTAALNDQWIDYAANEIDPNAIPWLYAILGYYDYNAKDSNKAKENMKKVLAFLDAQLLNKPFLTGFRVALADIIVVCSLFNFYKMVFEPTFRSPYVNVNRWFTTCINQPNFKAVIGEFALCEKMMVYVAPKKEVKEEKPKAAPKKEVKEDAGDDEVDEKPKKKNPLDELAPSTFVLDEFKRTYSNNEVSMSIPWFFEHFDKEGFSVYQCTYQYNHELGPVFKTCNLVGGFFQRLETLHKYAFASMIIFGEEQGGAVKDQTVSGLWVFRGQDLPADMKDCDDSLVYDWKKLDVAADKAIIESFLAWEDKNGGFAGKKFLQGKLYK", "length": 410 }, "evidence": [ { "id": "A0A9J7JHW4", "url": "https://omabrowser.org/oma/group/A0A9J7JHW4/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P26641-1", "protein_name": "Elongation factor 1-gamma", "gene_name": "EEF1G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVRRILGLLDAYLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAVLGEVKLCEKMAQFDAKKFAETQPKKDTPRKEKGSREEKQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYSEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEGAFQHVGKAFNQGKIFK", "length": 437 }, "evidence": [ { "id": "A0A9J7JHW4", "url": "https://omabrowser.org/oma/group/A0A9J7JHW4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P29547-1", "protein_name": "Elongation factor 1-gamma 1", "gene_name": "CAM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSQGTLYANFRIRTWVPRGLVKALKLDVKVVTPDAAAEQFARDFPLKKVPAFVGPKGYKLTEAMAINYYLVKLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAVDKIVDIFENRLKNYTYLATENISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASPFLKDEYKDFKFADKPLSPPQKKKEKKAPAAAPAASKKKEEAKPAATETETSSKKPKHPLELLGKSTFVLDDWKRKYSNEDTRPVALPWFWEHYNPEEYSLWKVTYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQDYVPAFDVAPDWESYDYAKLDPTNDDDKEFINNMWAWDKPVSVNGEPKEIVDGKVLK", "length": 415 }, "evidence": [ { "id": "A0A9J7JHW4", "url": "https://omabrowser.org/oma/group/A0A9J7JHW4/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3MHT4-1", "protein_name": "Speckle targeted PIP5K1A-regulated poly(A) polymerase", "gene_name": "Tut1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVDSDVVSLPRGRFRCCLCDVTTANRPSLDAHLKGRKHRDLVQLRATRKAQGLRSVFVSGFPRDVGSAQLSEYFQTFGPVANIVMDKDKGVFAIVEMGDISAREAVLSQPKHSLGGHTLRVRPREQKEFQSPASKSPKGVDSNSHQLAQALAEAADVGAQMVKLVELRELSEAERQLRTLVVALMQEVFTEFFPGCVVHPFGSSVNSFDVHGCDLDLFLDLGDMEEPQPDPQTPKLPEASSLDSTLASSLDPQVLACTPASLDSLSPTSLQDSEALDFETPSSLAPQTPDSALGSDTVTSPQSLPPVSPLEEDRGEGKHRKELELAEASKDEKEEATAVLELVGSILRGCVPGVYRVQTVPSARRPVVKFCHRPSGLHGDISLSNRLALYNSRFLNLCSEMDSRVRPLVYTLRCWAQHNGLSGGGPLLNNYALTLLVIYFLQTRDPPVLPTVAQLTQRSGEGEQVEVDGWDCSFPKDASRLEPSTNVEPLSSLLAQFFSCVSCWDLSGSLLSLREGQALMVAGGLPSDLWEGLRLGPMNLQDPFDLSHNVAANVTSRVAKRLQSSCGAAASYCRSLQYQQRSSRGRDWGLLPLLQPSSPSSLLSAKLIPLPSAPFPQIITALVSVLREALGCHIEQGTKRRRSEGARSKDSPLGGANKRPRLSGQEKSCEEGKEEPQGCAGDHSENEVEEMVIELRETPQDWALLHCGPPGELPLMTAKCLDKTAEQNPMEPEGAGEGSPGETEKEASHPSSVSWRCALWHQIWQGRRRARRRFQQQTKEEGRGGPSTGAEWLAVEARVTQELKGPKSEQQRLQGEPLLTFVASASQAEQTLTVAPLQDPQGLFPGLHHFLQVFIPQALKNLLK", "length": 866 }, "evidence": [ { "id": "A0A9J7JHW4", "url": "https://omabrowser.org/oma/group/A0A9J7JHW4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PE25-1", "protein_name": "Elongation factor 1-gamma", "gene_name": "eef1g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAGTLYTYPENWRAFKAQIAAQYSGARLKIASAPPAFTFGQTNRSPAFLGNFPLGKVPAYQGDDGFCLFESNAIAHYLSNDVLRGSTPQASAQVLQWVSFADSEVIPPASAWVFPTLGIMQFNKQATEQAKEEVKRVLAVLNQHLNTRTFLVGERISLADITVVCSLLWLYKQVLEPAFRQPYPNVTRWFVTCVNQPQFKTVLGEVKLCEKMAQFDAKKFAEMQPKKEAPIKKEKGGKEGGKQQPQQQEKKEKKKEEKKAAPAEEEMDECEAALASEPKAKDPFAHLPKSSFVMDEFKRKYSNEDTMTVALPYFWDHFDREGFSIWYAEYRFPEELTMAFMSCNLITGMFQRLDKLRKNAFASVILFGANNDSCISGIWVFRGQDLAFPLSDDWQIDYESYTWRKLDVDSEECKTMVKEYFAWEGEFKHVGKPFNQGKIFK", "length": 442 }, "evidence": [ { "id": "A0A9J7JHW4", "url": "https://omabrowser.org/oma/group/A0A9J7JHW4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D8N0-1", "protein_name": "Elongation factor 1-gamma", "gene_name": "Eef1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGTLYTYPENWRAFKALIAAQYSGAQVRVLSAPPHFHFGQTNRTPEFLRKFPAGKVPAFEGDDGFCVFESNAIAYYVSNEELRGSTPEAAAQVVQWVSFADSDIVPPASTWVFPTLGIMHHNKQATENAKEEVKRILGLLDTHLKTRTFLVGERVTLADITVVCTLLWLYKQVLEPSFRQAFPNTNRWFLTCINQPQFRAILGEVKLCEKMAQFDAKKFAESQPKKDTPRKEKGSREEKQKPQAERKEEKKAAAPAPEEEMDECEQALAAEPKAKDPFAHLPKSTFVLDEFKRKYSNEDTLSVALPYFWEHFDKDGWSLWYAEYRFPEELTQTFMSCNLITGMFQRLDKLRKNAFASVILFGTNNSSSISGVWVFRGQELAFPLSPDWQVDYESYTWRKLDPGSEETQTLVREYFSWEGTFQHVGKAVNQGKIFK", "length": 437 }, "evidence": [ { "id": "A0A9J7JHW4", "url": "https://omabrowser.org/oma/group/A0A9J7JHW4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NJH0-1", "protein_name": "Elongation factor 1-gamma", "gene_name": "eEF1gamma", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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This record is derived from a genomic sequence (NW_003615068.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003511314.1. 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[ "Protein Classification", "Other" ] }, { "id": "XP_003511314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511314", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "23324", "url": "https://www.rhea-db.org/rhea/23324", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LMN6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LMN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHZ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRVATRSCSLQVLAMNAPGGRRQEGRRAHRPREQDRDVQLSKALSYALRHGALKLGLPMRADGFVPLKALLQLPQFHSFSVEDVEHVVDTNGKQRLALQPGEPSTGPLIRANQGHSLQVPELELMPLETPQALPLMLVHGTFWKHWPSILLKGLSCQGRAHIHLASGLPGDPGVISGMRPNCEVVVFIDGPLALADGIPFFRSANGVILTPGNAEGVLLPKYFKEALQLRPTRKPLSLAGDQETEYQSGPKHSSRGGRRKIQQ", "length": 264, "header": "tr|A0A9J7JHZ2-1|A0A9J7JHZ2_CRIGR Isoform 1 of 2'-phosphotransferase OS=Cricetulus griseus OX=10029 GN=Trpt1 PE=3 SV=1 CANONICAL=A0A9J7JHZ2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LMN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ2/entry#A0A8C2LMN6-1", "sequence": { "sequence": "MNAPGGRRQEGRRAHRPREQDRDVQLSKALSYALRHGALKLGLPMRADGFVPLKALLQLPQFHSFSVEDVEHVVDTNGKQRLALQPGEPSTGPLIRANQGHSLQVPELELMPLETPQALPLMLVHGTFWKHWPSILLKGLSCQGRAHIHLASGLPGDPGVISGMRPNCEVVVFIDGPLALADGIPFFRSANGVILTPGNAEGVLLPKYFKEALQLRPTRKPLSLAGDQETEYQSGPKHSSRGGRRKIQQ", "length": 249, "header": "tr|A0A8C2LMN6-1|A0A8C2LMN6_CRIGR Computationally mapped isoform of 2'-phosphotransferase OS=Cricetulus griseus OX=10029 GN=Trpt1 PE=3 SV=1 CANONICAL=A0A9J7JHZ2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ2/entry#A0A9J7JHZ2-1", "sequence": { "sequence": "MGRVATRSCSLQVLAMNAPGGRRQEGRRAHRPREQDRDVQLSKALSYALRHGALKLGLPMRADGFVPLKALLQLPQFHSFSVEDVEHVVDTNGKQRLALQPGEPSTGPLIRANQGHSLQVPELELMPLETPQALPLMLVHGTFWKHWPSILLKGLSCQGRAHIHLASGLPGDPGVISGMRPNCEVVVFIDGPLALADGIPFFRSANGVILTPGNAEGVLLPKYFKEALQLRPTRKPLSLAGDQETEYQSGPKHSSRGGRRKIQQ", "length": 264, "header": "tr|A0A9J7JHZ2-1|A0A9J7JHZ2_CRIGR Isoform 1 of 2'-phosphotransferase OS=Cricetulus griseus OX=10029 GN=Trpt1 PE=3 SV=1 CANONICAL=A0A9J7JHZ2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756285", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756285", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M212-1", "protein_name": "2'-phosphotransferase", "gene_name": "Trpt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDWVLVMNAPGGRRQEGRRTHRPREQDRNVQLSKALSYALRHGALKLGLPMRADGFVPLQALLQLPQFHSFSIEDVQLVVDTNEKQRFTLQPGEPSTGPLIRANQGHSLQVPELELMPLETPQALPSTLVHGTFWKHWPSILLNGLSRQGRTHIHLASGLPGDSGVISGIRPNCEVAVFINGALALTDGIPFFCSVNGVILTPGNADGFLLPKYFKEALQLRPTRKPLSLTGDKETESQSGPKHSSRGGRRKIQ", "length": 254 }, "evidence": [ { "id": "A0A9J7JHZ2", "url": "https://omabrowser.org/oma/group/A0A9J7JHZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RQ02-1", "protein_name": "2'-phosphotransferase", "gene_name": "TRPT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLLLFTGLGHELWRKEAGSSRPRGRRAHRPREQDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGALLQLPQFRSFSAEDVQRVVDTNEKQRFTLQPGDPSTGPLIRANQGHSLQVPALELIPLETPQALPLMLVHGTFWRHWPSILLKGLSRQGRTHIHLAPGLPGDPGVISGMRPNCEVAVFINGPQALADGIPFFRSANGVILTPGNTDGVLLPKYFKEALQLRPTRKPLSLAGNGETECQHGPKHSSRGRRTTPQ", "length": 261 }, "evidence": [ { "id": "A0A9J7JHZ2", "url": "https://omabrowser.org/oma/group/A0A9J7JHZ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q12272-1", "protein_name": "tRNA 2'-phosphotransferase", "gene_name": "TPT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRQVLQKDKRDVQLSKALSYLLRHTAVKEKLTIDSNGYTPLKELLSHNRLKTHKCTVDDIHRIVKENDKQRFHIKTLGADEEWICATQGHSIKSIQPSDEVLVPITEASQLPQELIHGTNLQSVIKIIESGAISPMSRNHVHLSPGMLHAKGVISGMRSSSNVYIFIDCHSPLFFQTLKMFRSLNNVYLSSSIPVELIQKVVVKGNLKDEEKLDTLRRILHERNIPLEKI", "length": 230 }, "evidence": [ { "id": "A0A9J7JHZ2", "url": "https://omabrowser.org/oma/group/A0A9J7JHZ2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54L34-1", "protein_name": "2'-phosphotransferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSFQSLNPVNKSKSLVALSKSLSYVLRHGAEKEGLKIDSQGFIKVDDILKNNLFKNTNFKEIQEVVDTNDKKRYHMELNDSDGCYYIRANQGHTLENVDNVEMTKITSADQVGTVFHGTYRKHLQSILNEGLKKMDRNHIHCVNKIMGQEITSGMRGSCNMIVYIDVPLLLQDGIDLYLSQNNVALTDGLNNTGILPPKYFIKITDAKNDVTIWQHMRVKKKKIFIFIFFFFFFFFFFFLIFVLSNYFFFIFFIFFHFFFAPNPNFSNTHFGLGPQKKK", "length": 279 }, "evidence": [ { "id": "A0A9J7JHZ2", "url": "https://omabrowser.org/oma/group/A0A9J7JHZ2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5EAR5-1", "protein_name": "tRNA 2'-phosphotransferase 1", "gene_name": "trpt1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDCETRGRGRRGRGNRNEESRDVRLSKSLSYVLRHGASKMGLQMNSDGFVFVEELLAHQQFRSFSVDDVERVVASNDKQRFKLCKHPEDDRLQIRANQGHSVQVTDLELREISQDDQDYPREAVHGSYMKHWPSIRSQGLSRMNRTHIHLAPGLPGEGRVISGMRQSCDLAVYIDVTKAMSDGIKFFWSENGVLLTPGDAAGILAPCYFSRAQRLKPLPCDIELH", "length": 225 }, "evidence": [ { "id": "A0A9J7JHZ2", "url": "https://omabrowser.org/oma/group/A0A9J7JHZ2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86BH3-1", "protein_name": "2'-phosphotransferase", "gene_name": "Tpt", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASNQQINTQLSKKLSWLLRHGAKTEGITIRADGFVSVPDLQKHPRYLCFTLEKLKEIAAADAKQRYTLRWNPELGVHEIRANQGHSLAVLEGEAGGLENITHVSQVPLAVHGTYYRHWGAIRSQGLSRMNRNHVHFACSDETNSTLSGFRSDCQILIYLNVEKVLADGIPIYRSSNNVLLCPGIEGFIHSSYFQRVVDKKTGQPLQIDHCY", "length": 212 }, "evidence": [ { "id": "A0A9J7JHZ2", "url": "https://omabrowser.org/oma/group/A0A9J7JHZ2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86TN4-1", "protein_name": "tRNA 2'-phosphotransferase 1", "gene_name": "TRPT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFSGGGRQEAAGSRGRRAPRPREQDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGTLLQLPQFRGFSAEDVQRVVDTNRKQRFALQLGDPSTGLLIRANQGHSLQVPKLELMPLETPQALPPMLVHGTFWKHWPSILLKGLSCQGRTHIHLAPGLPGDPGIISGMRSHCEIAVFIDGPLALADGIPFFRSANGVILTPGNTDGFLLPKYFKEALQLRPTRKPLSLAGDEETECQSSPKHSSRERRRIQQ", "length": 253 }, "evidence": [ { "id": "A0A9J7JHZ2", "url": "https://omabrowser.org/oma/group/A0A9J7JHZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K3A2-1", "protein_name": "tRNA 2'-phosphotransferase 1", "gene_name": "Trpt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNAPGGRRKEGRRTHRPREQDRNVQLSKALSYALRHGALKLGLPMRADGFVPLQALLQLPQFHSFSIEDVQLVVNTNEKQRFTLQPGEPSTGLLIRANQGHSLQVPELELTPLETPQALPLTLVHGTFWKHWPSILLKGLSRQGRTHIHLASGLPGDPGVISGIRPNCEVAVFIDGPLALTDGIPFFCSANGVILTPGNAEGFLLPKYFKEALQLRPTRKPLSLAGDKETETQSGPKLSSRGGRRKIQQ", "length": 249 }, "evidence": [ { "id": "A0A9J7JHZ2", "url": "https://omabrowser.org/oma/group/A0A9J7JHZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tRNA 2'-phosphotransferase activity", "id": "GO:0000215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000215", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA splicing, via endonucleolytic cleavage and ligation", "id": "GO:0006388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006388", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "23324", "name": "", "equation": "2'-phospho-[ligated tRNA] + NAD(+) = mature tRNA + ADP-alpha-D-ribose 1'',2''-cyclic phosphate + nicotinamide", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A9J7JHZ2-1" ], "evidence": [ { "id": "23324", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23324" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A9J7JHZ2", "gene_name": "Trpt1", "activity": [ { "ec_number": "2.7.1.160", "activity": "2'-phospho-[ligated tRNA] + NAD(+) = mature tRNA + ADP-alpha-D-ribose 1'',2''-cyclic phosphate + nicotinamide.", "evidence": [ { "id": "A0A9J7JHZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ2" } ] }, { "ec_number": "2.7.1.160", "activity": "", "evidence": [ { "id": "A0A9J7JHZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.160", "ec_name": "2'-phospho-[ligated tRNA] + NAD(+) = mature tRNA + ADP-alpha-D-ribose 1'',2''-cyclic phosphate + nicotinamide.", "evidence": [ { "id": "2.7.1.160", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.160" }, { "id": "2.7.1.160", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.160" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JHZ3-1", "uniprot_ac": "A0A9J7JHZ3", "uniprot_id": "A0A9J7JHZ3_CRIGR", "mass": { "chemical_mass": 39455.0, "monoisotopic_mass": 39455.0 }, "refseq": { "ac": "XP_027271199", "name": "mitochondrial glycine transporter isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271199" }, "gene_names": [ { "name": "Slc25a38", "type": "recommended", "evidence": [ { "id": "A0A9J7JHZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3" } ] }, { "name": "SLC25A38", "type": "synonym", "evidence": [ { "id": "A0A9J7JHZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3" } ] }, { "name": "Slc25a38", "type": "synonym", "evidence": [ { "id": "XP_027271199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271199" } ] } ], "protein_names": [ { "name": "Mitochondrial glycine transporter", "type": "recommended", "evidence": [ { "id": "A0A9J7JHZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 25 member 38", "type": "synonym", "evidence": [ { "id": "A0A9J7JHZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial glycine transporter isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027271199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271199" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271199" } ] }, { "annotation": "Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3#function" }, { "database": "HAMAP", "id": "MF_03064", "url": "https://hamap.expasy.org/signature/MF_03064" }, { "database": "UniProtKB", "id": "A0A9J7JPL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPL6#function" }, { "database": "UniProtKB", "id": "A0A9J7JQN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQN8#function" }, { "database": "UniProtKB", "id": "A0A8C2LS13", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS13#function" } ] }, { "annotation": "Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3#function" }, { "database": "UniProtKB", "id": "ARBA00034083", "url": "https://www.uniprot.org/uniprotkb/ARBA00034083#function" }, { "database": "UniProtKB", "id": "A0A9J7JPL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPL6#function" }, { "database": "UniProtKB", "id": "A0A9J7JQN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQN8#function" }, { "database": "UniProtKB", "id": "A0A8C2LS13", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS13#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc25a38", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3", "locus": {} } ], "crossref": [ { "id": "100757130", "url": "https://www.ncbi.nlm.nih.gov/gene/100757130", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757130", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757130", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JHZ3", "url": "https://www.orthodb.org/?gene=A0A9J7JHZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46181:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46181:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271199", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "70715", "url": "https://www.rhea-db.org/rhea/70715", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LS13", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LS13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPL6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSDWHRGNGDATGWHWKQRLWSRFPGREEMAKEERDLACEEVEPPDTAEAQLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQPSDLRSRRVGMLAVFLKVVRTESLLGLWRGMSPDVLAVSTPAPQSSWSPMSGHQSIVRCVPGVGIYFGTLYSLKQYFLRGHPPTALESVILGMGSRSVAGVCMSPITVIKTRYESGTYSYESVYAALRSIYCSEGHRGLFRGLTATLLRDAPFSGLYLMFYSQTKTTVLRGTDQLDVALMPLVNFSCGILAGVLASLVTQPADVIKTHMQLSPVKSQWIGQAAALIFKNHGLRGFFHGSVPRALRRTLMAAMAWTVYEEMMARMGLKS", "length": 356, "header": "tr|A0A9J7JHZ3-1|A0A9J7JHZ3_CRIGR Isoform 1 of Mitochondrial glycine transporter OS=Cricetulus griseus OX=10029 GN=Slc25a38 PE=3 SV=1 CANONICAL=A0A9J7JHZ3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LS13-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3/entry#A0A8C2LS13-1", "sequence": { "sequence": "MGVSAEPQSLAVAGAGLASPVIEKARSALLPPQDVEDTVETLMLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQPSDLRSRRVGMLAVFLKVVRTESLLGLWRGMSPSIVRCVPGVGIYFGTLYSLKQYFLRGHPPTALESVILGMGSRSVAGVCMSPITVIKTRYESGTYSYESVYAALRSIYCSEGHRGLFRGLTATLLRDAPFSGLYLMFYSQTKTTVLRGTDQLDVALMPLVNFSCGILAGVLASLVTQPADVIKTHMQLSPVKSQWIGQAAALIFKNHGLRGFFHGSVPRALRRTLMAAMAWTVYEEMMARMGLKS", "length": 326, "header": "tr|A0A8C2LS13-1|A0A8C2LS13_CRIGR Computationally mapped isoform of Mitochondrial glycine transporter OS=Cricetulus griseus OX=10029 GN=Slc25a38 PE=3 SV=1 CANONICAL=A0A9J7JHZ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3/entry#A0A9J7JHZ3-1", "sequence": { "sequence": "MRSDWHRGNGDATGWHWKQRLWSRFPGREEMAKEERDLACEEVEPPDTAEAQLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQPSDLRSRRVGMLAVFLKVVRTESLLGLWRGMSPDVLAVSTPAPQSSWSPMSGHQSIVRCVPGVGIYFGTLYSLKQYFLRGHPPTALESVILGMGSRSVAGVCMSPITVIKTRYESGTYSYESVYAALRSIYCSEGHRGLFRGLTATLLRDAPFSGLYLMFYSQTKTTVLRGTDQLDVALMPLVNFSCGILAGVLASLVTQPADVIKTHMQLSPVKSQWIGQAAALIFKNHGLRGFFHGSVPRALRRTLMAAMAWTVYEEMMARMGLKS", "length": 356, "header": "tr|A0A9J7JHZ3-1|A0A9J7JHZ3_CRIGR Isoform 1 of Mitochondrial glycine transporter OS=Cricetulus griseus OX=10029 GN=Slc25a38 PE=3 SV=1 CANONICAL=A0A9J7JHZ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3/entry#A0A9J7JPL6-1", "sequence": { "sequence": "MRSDWHRGNGDATGWHWKQRLWSRFPGREEMAKEERDLACEEVEPPDTAEAQLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQPSDLRSRRVGMLAVFLKVVRTESLLGLWRGMSPSIVRCVPGVGIYFGTLYSLKQYFLRGHPPTALESVILGMGSRSVAGVCMSPITVIKTRYESGTYSYESVYAALRSIYCSEGHRGLFRGLTATLLRDAPFSGLYLMFYSQTKTTVLRGTDQLDVALMPLVNFSCGILAGVLASLVTQPADVIKTHMQLSPVKSQWIGQAAALIFKNHGLRGFFHGSVPRALRRTLMAAMAWTVYEEMMARMGLKS", "length": 335, "header": "tr|A0A9J7JPL6-1|A0A9J7JPL6_CRIGR Computationally mapped isoform of Mitochondrial glycine transporter OS=Cricetulus griseus OX=10029 GN=Slc25a38 PE=3 SV=1 CANONICAL=A0A9J7JHZ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3/entry#A0A9J7JQN8-1", "sequence": { "sequence": "MGVSAEPQSLAVAGAGLASPVIEKARSALLPPQDVEDTVETLMLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQPSDLRSRRVGMLAVFLKVVRTESLLGLWRGMSPDVLAVSTPAPQSSWSPMSGHQSIVRCVPGVGIYFGTLYSLKQYFLRGHPPTALESVILGMGSRSVAGVCMSPITVIKTRYESGTYSYESVYAALRSIYCSEGHRGLFRGLTATLLRDAPFSGLYLMFYSQTKTTVLRGTDQLDVALMPLVNFSCGILAGVLASLVTQPADVIKTHMQLSPVKSQWIGQAAALIFKNHGLRGFFHGSVPRALRRTLMAAMAWTVYEEMMARMGLKS", "length": 347, "header": "tr|A0A9J7JQN8-1|A0A9J7JQN8_CRIGR Computationally mapped isoform of Mitochondrial glycine transporter OS=Cricetulus griseus OX=10029 GN=Slc25a38 PE=3 SV=1 CANONICAL=A0A9J7JHZ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757130", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757130", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glycine transmembrane transporter activity", "id": "GO:0015187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015187", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "erythrocyte differentiation", "id": "GO:0030218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030218", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3" } ], "pmid": "" }, { "name": "glycine import into mitochondrion", "id": "GO:1904983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904983", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JHZ3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "70715", "name": "", "equation": "glycine(in) = glycine(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "70715", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/70715" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 272, "end_pos": 274 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JI40-1", "uniprot_ac": "A0A9J7JI40", "uniprot_id": "A0A9J7JI40_CRIGR", "mass": { "chemical_mass": 58057.0, "monoisotopic_mass": 58057.0 }, "refseq": { "ac": "XP_027260824", "name": "ubiquitin carboxyl-terminal hydrolase 17-like protein B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260824" }, "gene_names": [ { "name": "LOC113834607", "type": "recommended", "evidence": [ { "id": "A0A9J7JI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" } ] }, { "name": "LOC113834607", "type": "synonym", "evidence": [ { "id": "XP_027260824", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260824" } ] } ], "protein_names": [ { "name": "ubiquitinyl hydrolase 1", "type": "recommended", "evidence": [ { "id": "A0A9J7JI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40/entry#names_and_taxonomy" } ] }, { "name": "3.4.19.12", "type": "synonym", "evidence": [ { "id": "A0A9J7JI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin carboxyl-terminal hydrolase 17-like protein B", "type": "synonym", "evidence": [ { "id": "XP_027260824", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260824" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 20% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260824", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260824" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113834607", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40", "locus": {} } ], "crossref": [ { "id": "A0A9J7JI40", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JI40", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113834607", "url": "https://www.ncbi.nlm.nih.gov/gene/113834607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113834607", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113834607", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JI40", "url": "https://www.orthodb.org/?gene=A0A9J7JI40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24006:SF651", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24006:SF651", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260824", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260824", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JI40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAQRLSEVESPWKAGTGCKPSSHAVDSEVSSCSYGSADSAWSSPLAQDLHHDNAQETAELAARGKHSASWERPLGVGVGLLNTGNSCYLNAALQCLTHTPPLANYMLSREHSRSCCHHPGSCTMCALEAQVNQSLLHSKDVMQPSKILTGAFHRQKQEDAHEFLMFTLNAMHEACLRGRKPSEESSKDSTPIYEIFGGSWRSQVRCLQCQGTSDAFSPFLDVLLDIHEAPSVNQALEYLVKAEELCGENAYLCDNCQEKTPALKSLTIQGASKILLLVLKCSSDSAGGKMDRKVRYPESLNLVPYMSQSNRGPLVYFLYAALVHAGATCHTGHYFCYVRAGNGKWYKMDDSTVTRCEVASVLSESAYLLFYVQRTDGRGDSVNMPVGTGNKAHAGKGWQKKHKRGSCVQAAEPRRELEEAAAQAKSLDQWKVLEENKRPESGLNLKRPGFTPLADGVGIHRARSREDWDRNQPDKENRPWHDSSRFPPAPRAMDSGLLCSQEERARSKKKKKKPTWRPLPLY", "length": 524, "header": "tr|A0A9J7JI40-1|A0A9J7JI40_CRIGR Isoform 1 of ubiquitinyl hydrolase 1 OS=Cricetulus griseus OX=10029 GN=LOC113834607 PE=4 SV=1 CANONICAL=A0A9J7JI40-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JI40-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40/entry#A0A9J7JI40-1", "sequence": { "sequence": "MEAAQRLSEVESPWKAGTGCKPSSHAVDSEVSSCSYGSADSAWSSPLAQDLHHDNAQETAELAARGKHSASWERPLGVGVGLLNTGNSCYLNAALQCLTHTPPLANYMLSREHSRSCCHHPGSCTMCALEAQVNQSLLHSKDVMQPSKILTGAFHRQKQEDAHEFLMFTLNAMHEACLRGRKPSEESSKDSTPIYEIFGGSWRSQVRCLQCQGTSDAFSPFLDVLLDIHEAPSVNQALEYLVKAEELCGENAYLCDNCQEKTPALKSLTIQGASKILLLVLKCSSDSAGGKMDRKVRYPESLNLVPYMSQSNRGPLVYFLYAALVHAGATCHTGHYFCYVRAGNGKWYKMDDSTVTRCEVASVLSESAYLLFYVQRTDGRGDSVNMPVGTGNKAHAGKGWQKKHKRGSCVQAAEPRRELEEAAAQAKSLDQWKVLEENKRPESGLNLKRPGFTPLADGVGIHRARSREDWDRNQPDKENRPWHDSSRFPPAPRAMDSGLLCSQEERARSKKKKKKPTWRPLPLY", "length": 524, "header": "tr|A0A9J7JI40-1|A0A9J7JI40_CRIGR Isoform 1 of ubiquitinyl hydrolase 1 OS=Cricetulus griseus OX=10029 GN=LOC113834607 PE=4 SV=1 CANONICAL=A0A9J7JI40-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113834607", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113834607", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" } ], "pmid": "" }, { "name": "protein deubiquitination", "id": "GO:0016579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016579", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type deubiquitinase activity", "id": "GO:0004843", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004843", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI40", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JI40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI40" }, { "id": "PS50235", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50235" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "USP", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 376, "start_aa": "Val", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.19.12", "ec_name": "Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).", "evidence": [ { "id": "3.4.19.12", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.19.12" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JI47-1", "uniprot_ac": "A0A9J7JI47", "uniprot_id": "A0A9J7JI47_CRIGR", "mass": { "chemical_mass": 73971.0, "monoisotopic_mass": 73971.0 }, "refseq": { "ac": "XP_007651731", "name": "lebercilin-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651731" }, "gene_names": [ { "name": "Lca5l", "type": "recommended", "evidence": [ { "id": "A0A9J7JI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47" } ] }, { "name": "Lca5l", "type": "synonym", "evidence": [ { "id": "XP_007651731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651731" } ] } ], "protein_names": [ { "name": "Lebercilin-like protein", "type": "recommended", "evidence": [ { "id": "A0A9J7JI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47/entry#names_and_taxonomy" } ] }, { "name": "Leber congenital amaurosis 5-like protein", "type": "synonym", "evidence": [ { "id": "A0A9J7JI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47/entry#names_and_taxonomy" } ] }, { "name": "lebercilin-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007651731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651731" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615800.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007651731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651731" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lca5l", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47", "locus": {} } ], "crossref": [ { "id": "A0A9J7JI47", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JI47", "database": "AlphaFoldDB", "categories": [] }, { "id": "100753975", "url": "https://www.ncbi.nlm.nih.gov/gene/100753975", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028933", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028933", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753975", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753975", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JI47", "url": "https://www.orthodb.org/?gene=A0A9J7JI47", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16650", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16650", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16650:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16650:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007651731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GVA0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLWTMSLADTTKAHTTEHFPSLALGGNRRSAEGRSSPDKADNLSQNSGASNGSVDYSRSQCSYRSLASHYDYSEGFLSECSEANRHQLQQPLGKMEKRKFNSSKIPQLKGQKDITAEKKHIWNASVFNSQIQTIAKRRDAMTHRILSARLHKIKELKNELADIHRKLEATVIENQFLKQLQLRHLKAIGKYVNSQNNLPQITAKHQNEVKNLRQLLRKSQEKERIVSRKLRETDSELLRTKDALQALQKLSEDKNLAEREDLTRRLTVLTAKMETNDKKIQNLEKQLRLNNRSFSRQLAKENRKTLAAQTATKTLQGEVRQLHQKLKEKDRELEIKNIYTNRIFKNLHEKEDYPKVSSTKSVQADRKSLPFVNMRHQETQKSDVPSWTAKGKKTIGSIGHKEKSTEINHEISYCVCKLPKQEEPKRKYEDLPMEVEHPKPPACVETIRMQEEKREDQEKKVIPPEVEPIPRGSEAPEVTEAEVPAKAVAEVGGMLEARAAEDVEHGPYPRKTPRQRKHYSFTEATENLHHGLPTSCGLASGSPRCRHSMGTGKYRSDQDLQLEPAGYEPSFGKAARAKAKETAFRDKKNSLMEELFGSGFAGRVGPTTGGEAASKAQQLGPGQASASNAFGDSRATVVRSLQTSPAEGNKKTVI", "length": 655, "header": "tr|A0A9J7JI47-1|A0A9J7JI47_CRIGR Isoform 1 of Lebercilin-like protein OS=Cricetulus griseus OX=10029 GN=Lca5l PE=3 SV=1 CANONICAL=A0A9J7JI47-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GVA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47/entry#A0A9J7GVA0-1", "sequence": { "sequence": "MRLWTMSLADTTKAHTTEHFPSLALGGNRRSAEGRSSPDKADNLSQNSGASNGSVDYSRSQCSYRSLASHYDYSEGFLSECSEANRHQLQQPLGKMEKRKFNSSKIPQLKGQKDITAEKKHIWNASVFNSQIQTIAKRRDAMTHRILSARLHKIKELKNELADIHRKLEATVIENQFLKQLQLRHLKAIGKYVNSQNNLPQITAKHQNEVKNLRQLLRKSQEKERIVSRKLRETDSELLRTKDALQALQKLSEDKNLAEREDLTRRLTVLTAKMETNDKKIQNLEKQLRLNNRSFSRQLAKENRKTLAAQTATKTLQGEVRQLHQKLKEKDRELEIKNIYTNRIFKNLHEKEDYPKVSSTKSVQADRKSLPFVNMRHQETQKSDVPSWTAKIYQWRSNTQNHQPVWKLLGCKRRKGKIKRRKSSHQK", "length": 427, "header": "tr|A0A9J7GVA0-1|A0A9J7GVA0_CRIGR Computationally mapped isoform of Lebercilin-like protein OS=Cricetulus griseus OX=10029 GN=Lca5l PE=3 SV=1 CANONICAL=A0A9J7JI47-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JI47-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47/entry#A0A9J7JI47-1", "sequence": { "sequence": "MRLWTMSLADTTKAHTTEHFPSLALGGNRRSAEGRSSPDKADNLSQNSGASNGSVDYSRSQCSYRSLASHYDYSEGFLSECSEANRHQLQQPLGKMEKRKFNSSKIPQLKGQKDITAEKKHIWNASVFNSQIQTIAKRRDAMTHRILSARLHKIKELKNELADIHRKLEATVIENQFLKQLQLRHLKAIGKYVNSQNNLPQITAKHQNEVKNLRQLLRKSQEKERIVSRKLRETDSELLRTKDALQALQKLSEDKNLAEREDLTRRLTVLTAKMETNDKKIQNLEKQLRLNNRSFSRQLAKENRKTLAAQTATKTLQGEVRQLHQKLKEKDRELEIKNIYTNRIFKNLHEKEDYPKVSSTKSVQADRKSLPFVNMRHQETQKSDVPSWTAKGKKTIGSIGHKEKSTEINHEISYCVCKLPKQEEPKRKYEDLPMEVEHPKPPACVETIRMQEEKREDQEKKVIPPEVEPIPRGSEAPEVTEAEVPAKAVAEVGGMLEARAAEDVEHGPYPRKTPRQRKHYSFTEATENLHHGLPTSCGLASGSPRCRHSMGTGKYRSDQDLQLEPAGYEPSFGKAARAKAKETAFRDKKNSLMEELFGSGFAGRVGPTTGGEAASKAQQLGPGQASASNAFGDSRATVVRSLQTSPAEGNKKTVI", "length": 655, "header": "tr|A0A9J7JI47-1|A0A9J7JI47_CRIGR Isoform 1 of Lebercilin-like protein OS=Cricetulus griseus OX=10029 GN=Lca5l PE=3 SV=1 CANONICAL=A0A9J7JI47-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 608, "start_aa": "Thr", "end_pos": 608, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr608", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753975", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753975", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intraciliary transport", "id": "GO:0042073", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI47", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JI47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI47" }, { "id": "PF15619", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15619" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lebercilin", "eco_id": "ECO_0000259", "start_pos": 142, "end_pos": 334, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 608 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 124, "end_pos": 126 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JI62-1", "uniprot_ac": "A0A9J7JI62", "uniprot_id": "A0A9J7JI62_CRIGR", "mass": { "chemical_mass": 86809.0, "monoisotopic_mass": 86809.0 }, "refseq": { "ac": "XP_027261545", "name": "telomere repeats-binding bouquet formation protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261545" }, "gene_names": [ { "name": "Terb1", "type": "recommended", "evidence": [ { "id": "A0A9J7JI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62" } ] }, { "name": "Terb1", "type": "synonym", "evidence": [ { "id": "XP_027261545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261545" } ] } ], "protein_names": [ { "name": "Telomere repeats-binding bouquet formation protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7JI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 79", "type": "synonym", "evidence": [ { "id": "A0A9J7JI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62/entry#names_and_taxonomy" } ] }, { "name": "telomere repeats-binding bouquet formation protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027261545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261545" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027261545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261545" } ] }, { "annotation": "Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the MAJIN-TERB1-TERB2 complex, TERB1 probably mediates association with the shelterin/telosome complex via interaction with TERF1, promoting priming telomeric DNA attachment'. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62#function" }, { "database": "UniProtKB", "id": "ARBA00058244", "url": "https://www.uniprot.org/uniprotkb/ARBA00058244#function" }, { "database": "UniProtKB", "id": "A0A9J7K662", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K662#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Terb1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62", "locus": {} } ], "crossref": [ { "id": "A0A9J7JI62", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JI62", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11658", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11658", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767836", "url": "https://www.ncbi.nlm.nih.gov/gene/100767836", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767836", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767836", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JI62", "url": "https://www.orthodb.org/?gene=A0A9J7JI62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14014", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14014", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14014:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14014:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027261545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JI62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K662", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K662", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K662-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K662-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESENTKKIQEMKTDLNLLLECLKYHMGNPLSQKEVLITIHSVCQQNSDAGVYFREIGGLMFVKNLAKSSEHSMVKEAALYTLGSIAEENVYCQQTLCTSELFQDLSWFLSNDDSNTNLKRMSVYVLLVLVSNNRNGQTLVRETGCIKVLSQLFRTVLPNYELNLSDNNVFQSYLLWASVCSTLCVCVNNPQNDENQMLCCLLFPYANEWLMNCMKPEIIRPLCSFIGLTLANNTHVQNCFVSSGGLDVLSQVLVQLESDSHNTSSSAKLAVVVTKTVDACITNNLATFSLILSKYHIVSKLLALLLHESLDSGEKFSIILAIGHCTEDCEENQYELLKSNGLPLMIQALTEFKNEELNKAAIYVLHNCKKITEKLSLSQGENSFSENEADQIKGINEKENVEEHWKSAKEIICRMKQLEREGKEEKLQSGQCKDNTSPMKVKIQNNLKHLCEDSIGSNKAENKDINQSRQLHSFKSSGVTSKACANENQMKTLKKNTNPLNPCYREKGQNKILHKATSSCTQNLNEKMTFNQKDSVSQSSDHVVEHPTHIVKNGRQQVSVTDPFTLCLDIIDKEVGFQASDNCSKMLKYRCSGCIAVRKLLNSRNFSKLLHSCAYLCDHHKVIMEAEDKYKSELRKALICGKEILLTPRRRQLSKESTASEGLKAIHLKPDSQKLPSLEEHACNTSIPEAKARRFRVPGQHGLHKKRRIRKNFTKEEVNYLFHGVKKMGNHWNSILWSFPFQQGRRAVDLAHKYHKLIRGPNCAAI", "length": 767, "header": "tr|A0A9J7JI62-1|A0A9J7JI62_CRIGR Isoform 1 of Telomere repeats-binding bouquet formation protein 1 OS=Cricetulus griseus OX=10029 GN=Terb1 PE=3 SV=1 CANONICAL=A0A9J7JI62-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JI62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62/entry#A0A9J7JI62-1", "sequence": { "sequence": "MESENTKKIQEMKTDLNLLLECLKYHMGNPLSQKEVLITIHSVCQQNSDAGVYFREIGGLMFVKNLAKSSEHSMVKEAALYTLGSIAEENVYCQQTLCTSELFQDLSWFLSNDDSNTNLKRMSVYVLLVLVSNNRNGQTLVRETGCIKVLSQLFRTVLPNYELNLSDNNVFQSYLLWASVCSTLCVCVNNPQNDENQMLCCLLFPYANEWLMNCMKPEIIRPLCSFIGLTLANNTHVQNCFVSSGGLDVLSQVLVQLESDSHNTSSSAKLAVVVTKTVDACITNNLATFSLILSKYHIVSKLLALLLHESLDSGEKFSIILAIGHCTEDCEENQYELLKSNGLPLMIQALTEFKNEELNKAAIYVLHNCKKITEKLSLSQGENSFSENEADQIKGINEKENVEEHWKSAKEIICRMKQLEREGKEEKLQSGQCKDNTSPMKVKIQNNLKHLCEDSIGSNKAENKDINQSRQLHSFKSSGVTSKACANENQMKTLKKNTNPLNPCYREKGQNKILHKATSSCTQNLNEKMTFNQKDSVSQSSDHVVEHPTHIVKNGRQQVSVTDPFTLCLDIIDKEVGFQASDNCSKMLKYRCSGCIAVRKLLNSRNFSKLLHSCAYLCDHHKVIMEAEDKYKSELRKALICGKEILLTPRRRQLSKESTASEGLKAIHLKPDSQKLPSLEEHACNTSIPEAKARRFRVPGQHGLHKKRRIRKNFTKEEVNYLFHGVKKMGNHWNSILWSFPFQQGRRAVDLAHKYHKLIRGPNCAAI", "length": 767, "header": "tr|A0A9J7JI62-1|A0A9J7JI62_CRIGR Isoform 1 of Telomere repeats-binding bouquet formation protein 1 OS=Cricetulus griseus OX=10029 GN=Terb1 PE=3 SV=1 CANONICAL=A0A9J7JI62-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K662-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62/entry#A0A9J7K662-1", "sequence": { "sequence": "MESENTKKIQEMKTDLNLLLECLKYHMGNPLSQKEVLITIHSVCQQNSDAGVYFREIGGLMFVKNLAKSSEHSMVKEAALYTLGSIAEENVYCQQTLCTSELFQDLSWFLSNDDSNTNLKRMSVYVLLVLVSNNRNGQTLVRETGCIKVLSQLFRTVLPNYELNLSDNNVFQSYLLWASVCSTLCVCVNNPQNDENQMLCCLLFPYANEWLMNCMKPEIIRPLCSFIGLTLANNTHVQNCFVSSGGLDVLSQVLVQLESDSHNTSSSAKLAVVVTKTVDACITNNSTFSLILSKYHIVSKLLALLLHESLDSGEKFSIILAIGHCTEDCEENQYELLKSNGLPLMIQALTEFKNEELNKAAIYVLHNCKKITEKLSLSQGENSFSENEADQIKGINEKENVEEHWKSAKEIICRMKQLEREGKEEKLQSGQCKDNTSPMKVKIQNNLKHLCEDSIGSNKAENKDINQSRQLHSFKSSGVTSKACANENQMKTLKKNTNPLNPCYREKGQNKILHKATSSCTQNLNEKMTFNQKDSVSQSSDHVVEHPTHIVKNGRQQVSVTDPFTLCLDIIDKEVGFQASDNCSKMLKYRCSGCIAVRKLLNSRNFSKLLHSCAYLCDHHKVIMEAEDKYKSELRKALICGKEILLTPRRRQLSKESTASEGLKKRRIRKNFTKEEVNYLFHGVKKMGNHWNSILWSFPFQQGRRAVDLAHKYHKLIRGPNCAAI", "length": 725, "header": "tr|A0A9J7K662-1|A0A9J7K662_CRIGR Computationally mapped isoform of Telomere repeats-binding bouquet formation protein 1 OS=Cricetulus griseus OX=10029 GN=Terb1 PE=3 SV=1 CANONICAL=A0A9J7JI62-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767836", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767836", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "meiotic attachment of telomere to nuclear envelope", "id": "GO:0070197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070197", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 713, "end_pos": 715, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI62" }, { "id": "SM00717", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00717" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb-like", "eco_id": "ECO_0000259", "start_pos": 710, "end_pos": 761, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 467, "end_pos": 469 }, { "start_pos": 583, "end_pos": 585 }, { "start_pos": 606, "end_pos": 608 }, { "start_pos": 685, "end_pos": 687 }, { "start_pos": 713, "end_pos": 715 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JI68-1", "uniprot_ac": "A0A9J7JI68", "uniprot_id": "A0A9J7JI68_CRIGR", "mass": { "chemical_mass": 75078.0, "monoisotopic_mass": 75078.0 }, "refseq": { "ac": "XP_003501754", "name": "zinc finger protein 605 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501754" }, "gene_names": [ { "name": "Znf605", "type": "recommended", "evidence": [ { "id": "A0A9J7JI68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ] }, { "name": "Znf605", "type": "synonym", "evidence": [ { "id": "XP_003501754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501754" } ] } ], "protein_names": [ { "name": "Zinc finger protein 12", "type": "recommended", "evidence": [ { "id": "A0A9J7JI68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 605 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003501754", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501754" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613859.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003501754.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501754" } ] }, { "annotation": "Transcriptional repressor which suppresses activation protein 1 (AP-1)- and serum response element (SRE)-mediated transcriptional activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68#function" }, { "database": "UniProtKB", "id": "ARBA00055685", "url": "https://www.uniprot.org/uniprotkb/ARBA00055685#function" }, { "database": "UniProtKB", "id": "A0A9J7JQZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf605", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68", "locus": {} } ], "crossref": [ { "id": "A0A9J7JI68", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JI68", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767561", "url": "https://www.ncbi.nlm.nih.gov/gene/100767561", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767561", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767561", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JI68", "url": "https://www.orthodb.org/?gene=A0A9J7JI68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JQZ9", "url": "https://www.orthodb.org/?gene=A0A9J7JQZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24376:SF233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24376:SF233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501754", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501754", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JI68-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTESKISFEDVVVDFSWEEWQLLNPTQKSLYRDVVLENCSSLVFLGYQTIKPDVAFKLDQQEASLINEGILNQNFLEIWLDTSEVRSQNKQDKLKRKERGNGNDVSEKTSQSNMNSVRLEMIMHKCGKCEKSLKHPFDVKSNDGRKKIKASKKLLFYLKSDRPCGKVKYHGYKKCTKTSSKESRRFKNHLTKSGVYLCLECGKVFNQKSQITSHQKKHIKKKPYQYIRCGESFAQKSLLTIHQKTHSVEKPYGCNQCHRVFRSKSMYIQHQKIHTGEKPNTSSMGGKAFSKKPQQTGHEATHKINKPYVCSDCGKAFSQKLKLIIHQRKHTGEKPHKCSDCGKTFFWHSHLIIHQRSHTGKKPYECSECKKTFDENSLLIRHQRIHRGEKLYACRKCDETFIRKAQLIEHKMTHKREKKYQCCDCEETFFKKSELVRHQKSHLKEKPFRCDECGKRFFGKSQLLTHQRTHTGEKPYKCNECGKAFSQKSSVISHRRTHTGEKPYKCTECEKTFSEKSSLIHHQRTHTGEKPFECNDCGKAFAWKTQLLRHQRIHTGEKPFECNECGKAFVQKVQLIKHQKNHTGEKTYKCSDCGKAFFEKTQLMVHQRIHTGERPYNCGECGKSFTRKSHLLRHQAIHTRDK", "length": 642, "header": "tr|A0A9J7JI68-1|A0A9J7JI68_CRIGR Isoform 1 of Zinc finger protein 12 OS=Cricetulus griseus OX=10029 GN=Znf605 PE=3 SV=1 CANONICAL=A0A9J7JI68-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JI68-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68/entry#A0A9J7JI68-1", "sequence": { "sequence": "MTESKISFEDVVVDFSWEEWQLLNPTQKSLYRDVVLENCSSLVFLGYQTIKPDVAFKLDQQEASLINEGILNQNFLEIWLDTSEVRSQNKQDKLKRKERGNGNDVSEKTSQSNMNSVRLEMIMHKCGKCEKSLKHPFDVKSNDGRKKIKASKKLLFYLKSDRPCGKVKYHGYKKCTKTSSKESRRFKNHLTKSGVYLCLECGKVFNQKSQITSHQKKHIKKKPYQYIRCGESFAQKSLLTIHQKTHSVEKPYGCNQCHRVFRSKSMYIQHQKIHTGEKPNTSSMGGKAFSKKPQQTGHEATHKINKPYVCSDCGKAFSQKLKLIIHQRKHTGEKPHKCSDCGKTFFWHSHLIIHQRSHTGKKPYECSECKKTFDENSLLIRHQRIHRGEKLYACRKCDETFIRKAQLIEHKMTHKREKKYQCCDCEETFFKKSELVRHQKSHLKEKPFRCDECGKRFFGKSQLLTHQRTHTGEKPYKCNECGKAFSQKSSVISHRRTHTGEKPYKCTECEKTFSEKSSLIHHQRTHTGEKPFECNDCGKAFAWKTQLLRHQRIHTGEKPFECNECGKAFVQKVQLIKHQKNHTGEKTYKCSDCGKAFFEKTQLMVHQRIHTGERPYNCGECGKSFTRKSHLLRHQAIHTRDK", "length": 642, "header": "tr|A0A9J7JI68-1|A0A9J7JI68_CRIGR Isoform 1 of Zinc finger protein 12 OS=Cricetulus griseus OX=10029 GN=Znf605 PE=3 SV=1 CANONICAL=A0A9J7JI68-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68/entry#A0A9J7JQZ9-1", "sequence": { "sequence": "MNSVRLEMIMHKCGKCEKSLKHPFDVKSNDGRKKIKASKKLLFYLKSDRPCGKVKYHGYKKCTKTSSKESRRFKNHLTKSGVYLCLECGKVFNQKSQITSHQKKHIKKKPYQYIRCGESFAQKSLLTIHQKTHSVEKPYGCNQCHRVFRSKSMYIQHQKIHTGEKPNTSSMGGKAFSKKPQQTGHEATHKINKPYVCSDCGKAFSQKLKLIIHQRKHTGEKPHKCSDCGKTFFWHSHLIIHQRSHTGKKPYECSECKKTFDENSLLIRHQRIHRGEKLYACRKCDETFIRKAQLIEHKMTHKREKKYQCCDCEETFFKKSELVRHQKSHLKEKPFRCDECGKRFFGKSQLLTHQRTHTGEKPYKCNECGKAFSQKSSVISHRRTHTGEKPYKCTECEKTFSEKSSLIHHQRTHTGEKPFECNDCGKAFAWKTQLLRHQRIHTGEKPFECNECGKAFVQKVQLIKHQKNHTGEKTYKCSDCGKAFFEKTQLMVHQRIHTGERPYNCGECGKSFTRKSHLLRHQAIHTRDK", "length": 529, "header": "tr|A0A9J7JQZ9-1|A0A9J7JQZ9_CRIGR Computationally mapped isoform of Zinc finger protein 12 OS=Cricetulus griseus OX=10029 GN=Znf605 PE=3 SV=1 CANONICAL=A0A9J7JI68-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767561", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767561", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JI68", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JI68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 196, "end_pos": 223, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7JI68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JI68" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 77, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 280, "end_pos": 282 }, { "start_pos": 38, "end_pos": 40 }, { "start_pos": 581, "end_pos": 583 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JID1-1", "uniprot_ac": "A0A9J7JID1", "uniprot_id": "A0A9J7JID1_CRIGR", "mass": { "chemical_mass": 121477.0, "monoisotopic_mass": 121477.0 }, "refseq": { "ac": "XP_027271979", "name": "nuclear envelope pore membrane protein POM 121C isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271979" }, "gene_names": [ { "name": "Pom121c", "type": "recommended", "evidence": [ { "id": "A0A9J7JID1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1" } ] }, { "name": "Pom121c", "type": "synonym", "evidence": [ { "id": "XP_027271979", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271979" } ] } ], "protein_names": [ { "name": "Nuclear envelope pore membrane protein POM 121C isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7JID1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1/entry#names_and_taxonomy" } ] }, { "name": "nuclear envelope pore membrane protein POM 121C isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027271979", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271979" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027271979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271979" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JID1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pom121c", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1", "locus": {} } ], "crossref": [ { "id": "A0A9J7JID1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JID1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100762026", "url": "https://www.ncbi.nlm.nih.gov/gene/100762026", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762026", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762026", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JID1", "url": "https://www.orthodb.org/?gene=A0A9J7JID1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23193", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23193", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23193:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23193:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027271979", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027271979", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JID1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JID1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JR81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JR81-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPAAAVAGGVERRRPPLGVREGRGRTRGCGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRASRGLSSFVRDSRRQPRPALTASPPPAKPTVNGSVCEPRSPLGGPDPAELLLMGSYLGKPGPPQPALAQDPRDRPGRRPPSRSPPPTSAAQRVHHVYPALPTPLLRASRRLPHRDCGSLSNRFVITPRRRYPIQQAQYSLLGSLPTVCWNGGHKKAVLSARNSRMVCSPVTVRIAPPDSKLLRSPGPEQILNTTLSSPSSNAPDPCAKETVLSALKEKKKRTVEEEDQLHLDGQENKRRRHDSSGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLTSTCTGGIPSSSRNAITSSYSSTRGLSQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCPHSCSSAPLVTDKESPGEKVTDTATGKQQNSWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERKASLQWFNKVLEDKIDDASTSATETPPAANPPFTFTLPAAVGPAASPASLPVPMPSSNPLLESLKKMQDSPSPAPPSSEPTAAATTAAPSPLKTPSLLTPLVSPLTGPLASTSSDSKPTATFLGLAPASSATPLTDTKSPGVPQAEQAVSTPASTAPSPTPKPSMLFGMLNPPATSSLATTGPACSPMFKPIFMTTPKSETDSPLPSSSPATTTTTSPSTTLPTTASTTAPTFKPIFDSVEPITSMPLSAPFSLKQTTATATTTATPGPLFTGLATATSTVASGTTASASKLVFGFGVTTVASTANSTMTSTSQPLLFGGGPSVTTAGSAPPLSSIFQFGKPSATAASAASTSFTQSLASSAQTAASSSSSTGGFSGFGGTLATSTSAPSTTSQPTLTFSSTVTPAFNIPFSSGAKPALPTYPGANPQPTFGATEGATKPALAPSFGSSFTFGNSVAAAPSAAPAPATFGSAAQPAFGGLKATVSTFGTPASTQPAFGSTTSVFSFGSATTSGFGATTQTTHSGSSSSLFGSSTPSPFTFGGSAAPGSGGFGLGATPGTSSTSGTFSFGSGQSGATGTTTSFGGSLNTLGTSNQSSPFAFNVGSTPESKPVFGGTPTPTFGQSAPAPGVGTAGSSLSFGASSTPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK", "length": 1201, "header": "tr|A0A9J7JID1-1|A0A9J7JID1_CRIGR Isoform 1 of Nuclear envelope pore membrane protein POM 121C isoform X3 OS=Cricetulus griseus OX=10029 GN=Pom121c PE=4 SV=1 CANONICAL=A0A9J7JID1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JID1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1/entry#A0A9J7JID1-1", "sequence": { "sequence": "MSPAAAVAGGVERRRPPLGVREGRGRTRGCGGPAGAAALGLALLGLALYLVPAAAALAWLAVGASAAWWGLSREPRASRGLSSFVRDSRRQPRPALTASPPPAKPTVNGSVCEPRSPLGGPDPAELLLMGSYLGKPGPPQPALAQDPRDRPGRRPPSRSPPPTSAAQRVHHVYPALPTPLLRASRRLPHRDCGSLSNRFVITPRRRYPIQQAQYSLLGSLPTVCWNGGHKKAVLSARNSRMVCSPVTVRIAPPDSKLLRSPGPEQILNTTLSSPSSNAPDPCAKETVLSALKEKKKRTVEEEDQLHLDGQENKRRRHDSSGSGHSAFEPLVANGVPAAFVPKPGSLKRSLASQSSDDHLNKRSRTSSVSSLTSTCTGGIPSSSRNAITSSYSSTRGLSQLWKRSGPTSSPFSSPASSRSQTPERPAKKTREEEPCPHSCSSAPLVTDKESPGEKVTDTATGKQQNSWTSPPTPGSSGQRKRKIQLLPSRRGDQLTLPPPPELGYSITAEDLDMERKASLQWFNKVLEDKIDDASTSATETPPAANPPFTFTLPAAVGPAASPASLPVPMPSSNPLLESLKKMQDSPSPAPPSSEPTAAATTAAPSPLKTPSLLTPLVSPLTGPLASTSSDSKPTATFLGLAPASSATPLTDTKSPGVPQAEQAVSTPASTAPSPTPKPSMLFGMLNPPATSSLATTGPACSPMFKPIFMTTPKSETDSPLPSSSPATTTTTSPSTTLPTTASTTAPTFKPIFDSVEPITSMPLSAPFSLKQTTATATTTATPGPLFTGLATATSTVASGTTASASKLVFGFGVTTVASTANSTMTSTSQPLLFGGGPSVTTAGSAPPLSSIFQFGKPSATAASAASTSFTQSLASSAQTAASSSSSTGGFSGFGGTLATSTSAPSTTSQPTLTFSSTVTPAFNIPFSSGAKPALPTYPGANPQPTFGATEGATKPALAPSFGSSFTFGNSVAAAPSAAPAPATFGSAAQPAFGGLKATVSTFGTPASTQPAFGSTTSVFSFGSATTSGFGATTQTTHSGSSSSLFGSSTPSPFTFGGSAAPGSGGFGLGATPGTSSTSGTFSFGSGQSGATGTTTSFGGSLNTLGTSNQSSPFAFNVGSTPESKPVFGGTPTPTFGQSAPAPGVGTAGSSLSFGASSTPAQGFVGVGPFGSAAPSFSIGAGSKTPGARQRLQARRQHTRKK", "length": 1201, "header": "tr|A0A9J7JID1-1|A0A9J7JID1_CRIGR Isoform 1 of Nuclear envelope pore membrane protein POM 121C isoform X3 OS=Cricetulus griseus OX=10029 GN=Pom121c PE=4 SV=1 CANONICAL=A0A9J7JID1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JR81-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1/entry#A0A9J7JR81-1", "sequence": { "sequence": 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"length": 1160, "header": "tr|A0A9J7JR81-1|A0A9J7JR81_CRIGR Computationally mapped isoform of Nuclear envelope pore membrane protein POM 121C isoform X4 OS=Cricetulus griseus OX=10029 GN=Pom121c PE=4 SV=1 CANONICAL=A0A9J7JID1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1071, "start_aa": "Thr", "end_pos": 1071, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1071", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], 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"", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 407, "start_aa": "Thr", "end_pos": 407, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr407", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 472, "start_aa": "Thr", "end_pos": 472, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr472", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 675, "start_aa": "Thr", "end_pos": 675, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr675", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 781, "start_aa": "Thr", "end_pos": 781, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr781", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 919, "start_aa": "Thr", "end_pos": 919, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr919", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JID1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JID1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762026", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762026", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JID1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JID1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JID1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JID1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JID1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JID1" } ], "pmid": "" 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 129 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614921.1) and transcript sequence (IACG01032517.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016835261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835261" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Agfg2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9", "locus": {} } ], "crossref": [ { "id": "A0A9J7JIE9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JIE9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17903", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17903", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755409", "url": "https://www.ncbi.nlm.nih.gov/gene/100755409", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038508", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038508", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755409", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755409", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JIE9", "url": "https://www.orthodb.org/?gene=A0A9J7JIE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JRA1", "url": "https://www.orthodb.org/?gene=A0A9J7JRA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46134:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46134:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016835261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835261", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GY79", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRA1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JRA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRA1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVMAAKKGPGPGGGVGGSKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVLFLQSRGNEVCRKIWLGLFDARTSLIPDSRDPQKVKEFLQEKYEKKRWYVPPEQVKGPSYSRGGASTPVQGSVPEGKPVRTLLGDPVPSLSDAASSSSQSANQSQARTAQARSSQPSNKKASTDLLADIGGDPFAAPQVAPAFAAFPAFGGQTPSHGGFANFDAFSSNPGTSAFGSLPPSAQAPFQAQPPPAANRMLTGSYSFGTSRMSAFGVAPLAAATQPNSLTDVGGLLGPRVPAGGLSGSVFGMPSQVPALQSAVPGVSGNAGLTFGAFTNPFTTPAQPQLPSTNPFQPNGLASGPGFGMSSVGPGLLQPVPPTGVFASPFSAPMFPTQAALSEQQNGSCFGDLGTSKLGQRPLSQAPGISTNPFMTGASTFASKPPTTNPFL", "length": 483, "header": "tr|A0A9J7JIE9-1|A0A9J7JIE9_CRIGR Isoform 1 of Arf-GAP domain and FG repeat-containing protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Agfg2 PE=4 SV=1 CANONICAL=A0A9J7JIE9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GY79-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9/entry#A0A9J7GY79-1", "sequence": { "sequence": "MPPLLGHPSCPSVSRRGLNPPHRVKSISMTTFTEPEVLFLQSRGNEVCRKIWLGLFDARTSLIPDSRDPQKVKEFLQEKYEKKRWYVPPEQVKGPSYSRGGASTPVQGSVPEGKPVRTLLGDPVPSLSDAASSSSQSANQSQARTAQARSSQPSNKKASTDLLADIGGDPFAAPQVAPAFAAFPAFGGQTPSHGGFANFDAFSSNPGTSAFGSLPPSAQAPFQAQPPPAANRMLTGSYSFGTSRMSAFGVAPLAAATQPNSLTDVGGLLGPRVPAGGLSGSVFGMPSQVPALQSAVPGVSGNAGLTFGAFTNPFTTPAQPQLPSTNPFQPNGLASGPGFGMSSVGPGLLQPVPPTGVFASPFSAPMFPTQAALSEQQNGSCFGDLGTSKLGQRPLSQAPGISTNPFMTGASTFASKPPTTNPFL", "length": 424, "header": "tr|A0A9J7GY79-1|A0A9J7GY79_CRIGR Computationally mapped isoform of Arf-GAP domain and FG repeat-containing protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Agfg2 PE=4 SV=1 CANONICAL=A0A9J7JIE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9/entry#A0A9J7JIE9-1", "sequence": { "sequence": "MVMAAKKGPGPGGGVGGSKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVLFLQSRGNEVCRKIWLGLFDARTSLIPDSRDPQKVKEFLQEKYEKKRWYVPPEQVKGPSYSRGGASTPVQGSVPEGKPVRTLLGDPVPSLSDAASSSSQSANQSQARTAQARSSQPSNKKASTDLLADIGGDPFAAPQVAPAFAAFPAFGGQTPSHGGFANFDAFSSNPGTSAFGSLPPSAQAPFQAQPPPAANRMLTGSYSFGTSRMSAFGVAPLAAATQPNSLTDVGGLLGPRVPAGGLSGSVFGMPSQVPALQSAVPGVSGNAGLTFGAFTNPFTTPAQPQLPSTNPFQPNGLASGPGFGMSSVGPGLLQPVPPTGVFASPFSAPMFPTQAALSEQQNGSCFGDLGTSKLGQRPLSQAPGISTNPFMTGASTFASKPPTTNPFL", "length": 483, "header": "tr|A0A9J7JIE9-1|A0A9J7JIE9_CRIGR Isoform 1 of Arf-GAP domain and FG repeat-containing protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Agfg2 PE=4 SV=1 CANONICAL=A0A9J7JIE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JRA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9/entry#A0A9J7JRA1-1", "sequence": { "sequence": "MVMAAKKGPGPGGGVGGSKAEAEAASEVWCRRVRELGGCSQAGNRHCFECAQRGVTYVDITVGSFVCTTCSGLLRGLNPPHRVKSISMTTFTEPEVLFLQSRGNEVCRKIWLGLFDARTSLIPDSRDPQKVKEFLQEKYEKKRWYVPPEQVKGPSYSRGGASTPVQGSVPEGKPVRTLLGDPVPSLSDAASSSSQSANQSQARTAQARSSQPSNKKASTDLLADIGGDPFAAPQVAPAFAAFPAFGGQTPSHGGFANFDAFSSNPGTSAFGSLPPSAQAPFQAQPPPAGTSRMSAFGVAPLAAATQPNSLTDVGGLLGPRVPAGGLSGSVFGMPSQVPALQSAVPGVSGNAGLTFGAFTNPFTTPAQPQLPSTNPFQPNGLASGPGFGMSSVGPGLLQPVPPTGVFASPFSAPMFPTQAALSEQQNGSCFGDLGTSKLGQRPLSQAPGISTNPFMTGASTFASKPPTTNPFL", "length": 472, "header": "tr|A0A9J7JRA1-1|A0A9J7JRA1_CRIGR Computationally mapped isoform of Arf-GAP domain and FG repeat-containing protein 2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Agfg2 PE=4 SV=1 CANONICAL=A0A9J7JIE9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755409", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755409", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "acrosome assembly", "id": "GO:0001675", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001675", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" } ], "pmid": "" }, { "name": "spermatid nucleus differentiation", "id": "GO:0007289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007289", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7JIE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIE9" }, { "id": "PS50115", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arf-GAP", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 153, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 198, "end_pos": 200 }, { "start_pos": 437, "end_pos": 439 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7JIF4-1", "uniprot_ac": "A0A9J7JIF4", "uniprot_id": "A0A9J7JIF4_CRIGR", "mass": { "chemical_mass": 28487.0, "monoisotopic_mass": 28487.0 }, "refseq": { "ac": "XP_027272066", "name": "protein phosphatase 1 regulatory subunit 35-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272066" }, "gene_names": [ { "name": "LOC113835691", "type": "recommended", "evidence": [ { "id": "A0A9J7JIF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF4" } ] }, { "name": "LOC113835691", "type": "synonym", "evidence": [ { "id": "XP_027272066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272066" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 35-like isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7JIF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF4/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 35-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027272066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272066" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027272066.1. 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF4" }, { "id": "PF15503", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15503" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein phosphatase 1 regulatory subunit 35 C-terminal", "eco_id": "ECO_0000259", "start_pos": 112, "end_pos": 260, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 17% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027261934.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027261934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261934" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIF9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rnf150", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF9", "locus": {} } ], "crossref": [ { "id": "A0A9J7JIF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JIF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02122", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02122", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16805", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16805", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774190", "url": "https://www.ncbi.nlm.nih.gov/gene/100774190", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003137", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774190", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774190", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7JIF9", "url": "https://www.orthodb.org/?gene=A0A9J7JIF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46539", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46539", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46539:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46539:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027261934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261934", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7JIF9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREGDAEPRSRTPGSPTPPQARGARSVSPPLSPGKPDASAARRLRGDRAGFARSPGIRSPQRLRVPAGAPPAREKDGAGGGRRGRGGDPGERREVAMSLIQACRSLALSTWLLSFCFVHLLCLDFTVAEKEEWYTAFVNITYAEPEPGAAVAGGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDPNTKFAAPAHGKHWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNTNETITMPHAGVEDIVAIMIPEPKGKEIVSLLERNITVTMHITIGTRNLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQVRTIRKGDKETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPIDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVGALQVVQDPDPVPQEGEAIFTTNSDQEPAVSSGSDISLIMALDVGLSDVELSTDQDYEEVKS", "length": 531, "header": "tr|A0A9J7JIF9-1|A0A9J7JIF9_CRIGR Isoform 1 of RING finger protein 150 OS=Cricetulus griseus OX=10029 GN=Rnf150 PE=4 SV=1 CANONICAL=A0A9J7JIF9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7JIF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF9/entry#A0A9J7JIF9-1", "sequence": { "sequence": "MREGDAEPRSRTPGSPTPPQARGARSVSPPLSPGKPDASAARRLRGDRAGFARSPGIRSPQRLRVPAGAPPAREKDGAGGGRRGRGGDPGERREVAMSLIQACRSLALSTWLLSFCFVHLLCLDFTVAEKEEWYTAFVNITYAEPEPGAAVAGGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLACDPNTKFAAPAHGKHWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNTNETITMPHAGVEDIVAIMIPEPKGKEIVSLLERNITVTMHITIGTRNLQKYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQVRTIRKGDKETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPIDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVGALQVVQDPDPVPQEGEAIFTTNSDQEPAVSSGSDISLIMALDVGLSDVELSTDQDYEEVKS", "length": 531, "header": "tr|A0A9J7JIF9-1|A0A9J7JIF9_CRIGR Isoform 1 of RING finger protein 150 OS=Cricetulus griseus OX=10029 GN=Rnf150 PE=4 SV=1 CANONICAL=A0A9J7JIF9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIJ4" } ] }, { "name": "Clmn", "type": "synonym", "evidence": [ { "id": "XP_027272269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272269" } ] } ], "protein_names": [ { "name": "Calmin", "type": "recommended", "evidence": [ { "id": "A0A9J7JIJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIJ4/entry#names_and_taxonomy" } ] }, { "name": "Calponin-like transmembrane domain protein", "type": "synonym", "evidence": [ { "id": "A0A9J7JIJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIJ4/entry#names_and_taxonomy" } ] }, { "name": "calmin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027272269", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272269" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027272269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272269" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIJ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Clmn", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIJ4", "locus": {} } ], "crossref": [ { "id": "A0A9J7JIJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7JIJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21245", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21245", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768555", "url": "https://www.ncbi.nlm.nih.gov/gene/100768555", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036872", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036872", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047827", "database": "InterPro", 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"length": 1009, "header": "tr|A0A8C2MQE6-1|A0A8C2MQE6_CRIGR Computationally mapped isoform of Calmin OS=Cricetulus griseus OX=10029 GN=Clmn PE=4 SV=1 CANONICAL=A0A9J7JIJ4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIJ4/entry#A0A9J7JIJ4-1", "sequence": { "sequence": "MAAQEWDWFQREELIGQISDIRVQNLQVERENVQKRTFTRWINLHLEKCDPPLEVTDLFIDIQDGKILMALLEVLSGRNLLHEYKSSSHRIFRLNNIAKALKFLEDSNVKLVSIDAAEIADGNPSLVLGLIWNIILFFQIKELTGNLSRGSPSSSLSPGSGGTDSDSSYPPTPTTERNVAVSVKDQRKAIKTMLAWVQRKTRKYGVAVQDFAGSWRSGLAFLAVIKAIDPSLVDMKQALEDSTRENLEKAFSIAHDTLHIPRLLEPEDIMVDMPDEQSIVTYVAQFLERFPELEPEEFVNLDREAPIESTFVRIKESPSEQESRVLLLSENGERAYTVNHETSHPPPAKVFVCDEPENEKGFCLGTVPSHKLSDSATEIMHQIIDQVLQGSPGRTGPTNEPAPESSILSTRKDGRRSNSLPIKKSVHFEADLHRDASCSKDPFYSSDFRFEGSPKVAKELSKQDVPVSLVEVAKEKKTEQEARPTASEKGPGDIVGVDGMPYHGQPPQDPSFCNGTVESLASHGEKGPSPPSPGVHTILATSTELKVPLLTVEPMDKDDYFEGIPLKASKFNRDLADFASTSQACGEDTSTHEKTPGEEEGFENYAEKLGKRKSKSPHAETEAPESQEEPDSHEPPPKGPEQEDPEHPLPPEETPADKKPEVYEKAKRKSTRHRSEEGEAEGLSGVSGEMPSNPPSTSVSLETLRSHSEEGLDFKPSPPLSKISVIPHDLFYYPHYEVPLAAVLEAYAEGGEDLKGEDIELEEVEEGFLQDSREEEEEAHSSQSSCSFSLPVDNGQPSVGDQESHVDGNSEGPTTASGPGSPSSHENHQQRETKENGPVESQQPQEPLNPELPTKPLQEKSMGASTSSKKKEKRKHVDQVENSLFIAPGTVRSSDDLEENPCEHKIPSRNSHSDSSIYIRRHANRSLELDHFSYVQLRNAADLDERRNRVLNRYNSQKLTELILQFYGIRADMKREFKHARLSMNGTNSSGEAVPLGSQSPASDSLTQFVQQPDVFYFILFLWLLVYCLLLFPQLDVSRL", "length": 1040, "header": "tr|A0A9J7JIJ4-1|A0A9J7JIJ4_CRIGR Isoform 1 of Calmin OS=Cricetulus griseus OX=10029 GN=Clmn PE=4 SV=1 CANONICAL=A0A9J7JIJ4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 172, "start_aa": "Thr", "end_pos": 172, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr172", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 814, "start_aa": "Thr", "end_pos": 814, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr814", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIJ4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIJ4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768555", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768555", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIJ4" } ], "pmid": "" }, { "name": "nuclear outer membrane", "id": "GO:0005640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005640", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7JIJ4", "url": 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